21820-51-9,MFCD00002603
Catalog No.:AA003TEW

21820-51-9 | O-Phospho-l-tyrosine

Pack Size
Purity
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250mg
95%
in stock  
$42.00   $29.00
- +
1g
95%
in stock  
$75.00   $53.00
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5g
95%
in stock  
$270.00   $189.00
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25g
95%
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$1,080.00   $756.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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Technical Information
Catalog Number:
AA003TEW
Chemical Name:
O-Phospho-l-tyrosine
CAS Number:
21820-51-9
Molecular Formula:
C9H12NO6P
Molecular Weight:
261.1684
MDL Number:
MFCD00002603
SMILES:
OC(=O)[C@H](Cc1ccc(cc1)OP(=O)(O)O)N
Properties
Properties
 
BP:
590.1°C at 760 mmHg  
Form:
Solid  
MP:
226-227°C  
Storage:
Keep in dry area;-20 ℃;  

Computed Properties
 
Complexity:
309  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-2.8  

Downstream Synthesis Route

[1]HelveticaChimicaActa,1945,vol.28,p.1258,1266

105-43-1    1119-62-6    57260-73-8    21820-51-9   
Phosphoricacidmono-(4-{(S)-2-(3-mercapto-propionylamino)-2-2-(3-methyl-pentanoylamino)-ethylcarbamoyl-ethyl}-phenyl)ester 

[1]JournalofMedicinalChemistry,2000,vol.43,p.1173-1179

105-43-1    1119-62-6    21820-51-9    75178-96-0   
Phosphoricacidmono-(4-{(S)-2-(3-mercapto-propionylamino)-2-3-(3-methyl-pentanoylamino)-propylcarbamoyl-ethyl}-phenyl)ester 

[1]JournalofMedicinalChemistry,2000,vol.43,p.1173-1179

105-43-1    1119-62-6    21820-51-9    51644-96-3   
Phosphoricacidmono-(4-{(S)-2-(3-mercapto-propionylamino)-2-5-(3-methyl-pentanoylamino)-pentylcarbamoyl-ethyl}-phenyl)ester 

[1]JournalofMedicinalChemistry,2000,vol.43,p.1173-1179

105-43-1    1119-62-6    21820-51-9    108467-99-8   
Phosphoricacidmono-4-((S)-2-(3-mercapto-propionylamino)-2-{3-(3-methyl-pentanoylamino)-methyl-benzylcarbamoyl}-ethyl)-phenylester 

[1]JournalofMedicinalChemistry,2000,vol.43,p.1173-1179

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Title: RhoA/ROCK-dependent moesin phosphorylation regulates AGE-induced endothelial cellular response.

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Journal: PLoS computational biology 20120101

Title: Genetic evidence for an indispensable role of somatic embryogenesis receptor kinases in brassinosteroid signaling.

Journal: PLoS genetics 20120101

Title: Dynamic ligand modulation of EPO receptor pools, and dysregulation by polycythemia-associated EPOR alleles.

Journal: PloS one 20120101

Title: Novel nonphosphorylated peptides with conserved sequences selectively bind to Grb7 SH2 domain with affinity comparable to its phosphorylated ligand.

Journal: PloS one 20120101

Title: Wnt4 participates in the formation of vertebrate neuromuscular junction.

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Title: Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury.

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Title: Identifying mechanisms by which Escherichia coli O157:H7 subverts interferon-γ mediated signal transducer and activator of transcription-1 activation.

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Title: Critical roles of the WASP N-terminal domain and Btk in LPS-induced inflammatory response in macrophages.

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Title: Evaluating translocation gene fusions by SNP array data.

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Journal: PloS one 20120101

Title: Decreased autocrine EGFR signaling in metastatic breast cancer cells inhibits tumor growth in bone and mammary fat pad.

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Title: 14-3-3ζ interacts with stat3 and regulates its constitutive activation in multiple myeloma cells.

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Title: High-resolution whole-mount in situ hybridization using Quantum Dot nanocrystals.

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Title: The Drosophila TRPP cation channel, PKD2 and Dmel/Ced-12 act in genetically distinct pathways during apoptotic cell clearance.

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Title: ALK-activating homologous mutations in LTK induce cellular transformation.

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Title: Post-Translational Modifications of Kaposi's Sarcoma-Associated Herpesvirus Regulatory Proteins - SUMO and KSHV.

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Title: Over-expression of PDGFR-β promotes PDGF-induced proliferation, migration, and angiogenesis of EPCs through PI3K/Akt signaling pathway.

Journal: PloS one 20120101

Title: RET PLCγ phosphotyrosine binding domain regulates Ca2+ signaling and neocortical neuronal migration.

Journal: PloS one 20120101

Title: Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migration.

Journal: Scientific reports 20120101

Title: HMGA1 is a novel downstream nuclear target of the insulin receptor signaling pathway.

Journal: Scientific reports 20120101

Title: Glucose enhances leptin signaling through modulation of AMPK activity.

Journal: PloS one 20120101

Title: Finding the smoking gun: protein tyrosine phosphatases as tools and targets of unicellular microorganisms and viruses.

Journal: Current medicinal chemistry 20120101

Title: Integrin β3 crosstalk with VEGFR accommodating tyrosine phosphorylation as a regulatory switch.

Journal: PloS one 20120101

Title: Identification of CMTM7 as a transmembrane linker of BLNK and the B-cell receptor.

Journal: PloS one 20120101

Title: A novel classification of lung cancer into molecular subtypes.

Journal: PloS one 20120101

Title: Ephrin-A1-mediated dopaminergic neurogenesis and angiogenesis in a rat model of Parkinson's disease.

Journal: PloS one 20120101

Title: Effects of halogenation on tyrosine phosphorylation and peptide binding to the SRC homology 2 domain of lymphocyte-specific protein tyrosine kinase.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Genetic susceptibility on CagA-interacting molecules and gene-environment interaction with phytoestrogens: a putative risk factor for gastric cancer.

Journal: PloS one 20120101

Title: Sprouty4 is an endogenous negative modulator of TrkA signaling and neuronal differentiation induced by NGF.

Journal: PloS one 20120101

Title: Spleen tyrosine kinase regulates AP-1 dependent transcriptional response to minimally oxidized LDL.

Journal: PloS one 20120101

Title: Ligand mobility modulates immunological synapse formation and T cell activation.

Journal: PloS one 20120101

Title: Transforming and tumorigenic activity of JAK2 by fusion to BCR: molecular mechanisms of action of a novel BCR-JAK2 tyrosine-kinase.

Journal: PloS one 20120101

Title: Actin-dependent activation of serum response factor in T cells by the viral oncoprotein tip.

Journal: Cell communication and signaling : CCS 20120101

Title: Structural stability of human protein tyrosine phosphatase ρ catalytic domain: effect of point mutations.

Journal: PloS one 20120101

Title: KAI1 suppresses HIF-1α and VEGF expression by blocking CDCP1-enhanced Src activation in prostate cancer.

Journal: BMC cancer 20120101

Title: Nef alleles from all major HIV-1 clades activate Src-family kinases and enhance HIV-1 replication in an inhibitor-sensitive manner.

Journal: PloS one 20120101

Title: A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblasts.

Journal: Skeletal muscle 20120101

Title: Modeling and simulation of aggregation of membrane protein LAT with molecular variability in the number of binding sites for cytosolic Grb2-SOS1-Grb2.

Journal: PloS one 20120101

Title: New model of macrophage acquisition of the lymphatic endothelial phenotype.

Journal: PloS one 20120101

Title: Toxin-based targeted therapy for malignant brain tumors.

Journal: Clinical & developmental immunology 20120101

Title: Characterization of magnesium requirement of human 5'-tyrosyl DNA phosphodiesterase mediated reaction.

Journal: BMC research notes 20120101

Title: Reduced serotonin reuptake transporter (SERT) function causes insulin resistance and hepatic steatosis independent of food intake.

Journal: PloS one 20120101

Title: Oxidative stress induced interleukin-32 mRNA expression in human bronchial epithelial cells.

Journal: Respiratory research 20120101

Title: Signaling-mediated control of ubiquitin ligases in endocytosis.

Journal: BMC biology 20120101

Title: In silico profiling of deleterious amino acid substitutions of potential pathological importance in haemophlia A and haemophlia B.

Journal: Journal of biomedical science 20120101

Title: Characterization of the effects of cross-linking of macrophage CD44 associated with increased phagocytosis of apoptotic PMN.

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Title: Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab.

Journal: BMC medicine 20120101

Title: N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity.

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Title: The adaptor molecule Nck localizes the WAVE complex to promote actin polymerization during CEACAM3-mediated phagocytosis of bacteria.

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Title: The role of C2 domains in PKC signaling.

Journal: Advances in experimental medicine and biology 20120101

Title: Inhibition of protein tyrosine phosphatase improves angiogenesis via enhancing Ang-1/Tie-2 signaling in diabetes.

Journal: Experimental diabetes research 20120101

Title: The malnutrition of obesity: micronutrient deficiencies that promote diabetes.

Journal: ISRN endocrinology 20120101

Title: Genetic variations in APPL2 are associated with overweight and obesity in a Chinese population with normal glucose tolerance.

Journal: BMC medical genetics 20120101

Title: Short-term treatment with bisphenol-A leads to metabolic abnormalities in adult male mice.

Journal: PloS one 20120101

Title: Sequence variations of latent membrane protein 2A in Epstein-Barr virus-associated gastric carcinomas from Guangzhou, southern China.

Journal: PloS one 20120101

Title: Epstein-Barr virus LMP2A signaling in statu nascendi mimics a B cell antigen receptor-like activation signal.

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Title: Confining domains lead to reaction bursts: reaction kinetics in the plasma membrane.

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Title: The tyrosine kinase c-Src directly mediates growth factor-induced Notch-1 and Furin interaction and Notch-1 activation in pancreatic cancer cells.

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Title: Internalization and down-regulation of the ALK receptor in neuroblastoma cell lines upon monoclonal antibodies treatment.

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Title: Cortactin tyrosine phosphorylation promotes its deacetylation and inhibits cell spreading.

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Title: Tyrosine phosphorylation of the E3 ubiquitin ligase TRIM21 positively regulates interaction with IRF3 and hence TRIM21 activity.

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Title: Skin regeneration in adult axolotls: a blueprint for scar-free healing in vertebrates.

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Title: Characterisation of bovine leukocyte Ig-like receptors.

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Title: Computational identification and modeling of crosstalk between phosphorylation, O-β-glycosylation and methylation of FoxO3 and implications for cancer therapeutics.

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Title: CagI is an essential component of the Helicobacter pylori Cag type IV secretion system and forms a complex with CagL.

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Title: Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling.

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Title: Distribution of cytoskeletal components in endothelial cells in the Guinea pig renal artery.

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Title: Insulin in central nervous system: more than just a peripheral hormone.

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Title: Macrophage Migration and Its Regulation by CSF-1.

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Title: IQGAP Family Members in Yeast, Dictyostelium, and Mammalian Cells.

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Title: The amyloid precursor protein intracellular domain-fe65 multiprotein complexes: a challenge to the amyloid hypothesis for Alzheimer's disease?

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Title: A molecular model for the differential activation of STAT3 and STAT6 by the herpesviral oncoprotein tip.

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Title: Protein tyrosine phosphatase 1B deficiency potentiates PERK/eIF2α signaling in brown adipocytes.

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Title: Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model.

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Title: Identification of JAK2 as a mediator of FIP1L1-PDGFRA-induced eosinophil growth and function in CEL.

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Title: The Concept of Divergent Targeting through the Activation and Inhibition of Receptors as a Novel Chemotherapeutic Strategy: Signaling Responses to Strong DNA-Reactive Combinatorial Mimicries.

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Title: Protein Kinase A Subunit α Catalytic and A Kinase Anchoring Protein 79 in Human Placental Mitochondria.

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Title: Vimentin and PSF act in concert to regulate IbeA+ E. coli K1 induced activation and nuclear translocation of NF-κB in human brain endothelial cells.

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Title: The EYA tyrosine phosphatase activity is pro-angiogenic and is inhibited by benzbromarone.

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Title: Drosophila eyes absent is a novel mRNA target of the tristetraprolin (TTP) protein DTIS11.

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Title: YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation.

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Title: Intra-aortic clusters undergo endothelial to hematopoietic phenotypic transition during early embryogenesis.

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Title: Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

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Title: The insulin receptor substrate 1 (IRS1) in intestinal epithelial differentiation and in colorectal cancer.

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Title: RAB-7 antagonizes LET-23 EGFR signaling during vulva development in Caenorhabditis elegans.

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Title: Protocadherin-18 is a novel differentiation marker and an inhibitory signaling receptor for CD8+ effector memory T cells.

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Title: Integrin signaling in cancer cell survival and chemoresistance.

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Title: Human cataract mutations in EPHA2 SAM domain alter receptor stability and function.

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Title: A simple matter of life and death-the trials of postnatal Beta-cell mass regulation.

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Title: The Fyn-STAT5 Pathway: A New Frontier in IgE- and IgG-Mediated Mast Cell Signaling.

Journal: Frontiers in immunology 20120101

Title: Modeling the interactions of Alzheimer-related genes from the whole brain microarray data and diffusion tensor images of human brain.

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Title: Cross-phosphorylation, signaling and proliferative functions of the Tyro3 and Axl receptors in Rat2 cells.

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Title: VENNTURE--a novel Venn diagram investigational tool for multiple pharmacological dataset analysis.

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Title: GIT2 acts as a potential keystone protein in functional hypothalamic networks associated with age-related phenotypic changes in rats.

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Title: Vitronectin increases vascular permeability by promoting VE-cadherin internalization at cell junctions.

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Title: Chemical inhibition of bacterial protein tyrosine phosphatase suppresses capsule production.

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Title: Fibroblast growth factor signaling potentiates VE-cadherin stability at adherens junctions by regulating SHP2.

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Title: Activation of human neutrophils by the anti-inflammatory mediator Esenbeckia leiocarpa leads to atypical apoptosis.

Journal: Mediators of inflammation 20120101

Title: Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advances.

Journal: Frontiers in endocrinology 20120101

Title: In Vivo Consequences of Disrupting SH3-Mediated Interactions of the Inducible T-Cell Kinase.

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Title: The Role of Elongin BC-Containing Ubiquitin Ligases.

Journal: Frontiers in oncology 20120101

Title: Role of STAT3 in Transformation and Drug Resistance in CML.

Journal: Frontiers in oncology 20120101

Title: ALK Signaling and Target Therapy in Anaplastic Large Cell Lymphoma.

Journal: Frontiers in oncology 20120101

Title: Cytoskeleton in mast cell signaling.

Journal: Frontiers in immunology 20120101

Title: The Role of Insulin and Insulin-Like Growth Factor-1/FoxO-Mediated Transcription for the Pathogenesis of Obesity-Associated Dementia.

Journal: Current gerontology and geriatrics research 20120101

Title: Regulation of signaling at regions of cell-cell contact by endoplasmic reticulum-bound protein-tyrosine phosphatase 1B.

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Title: Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration.

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Title: ALK Inhibitors, a Pharmaceutical Perspective.

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Title: A Screening Method for the ALK Fusion Gene in NSCLC.

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Title: ROR1 and ROR2 in Human Malignancies: Potentials for Targeted Therapy.

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Title: Radiation induces acute alterations in neuronal function.

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Title: Role of phosphatidylinositol-3-kinase pathway in head and neck squamous cell carcinoma.

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Title: Intranasal 'painless' human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice.

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Title: Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease.

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Title: All in the Family: How the APPs Regulate Neurogenesis.

Journal: Frontiers in neuroscience 20120101

Title: Tyrosine phosphorylation of botulinum neurotoxin protease domains.

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Title: p38MAPK, ERK and PI3K signaling pathways are involved in C5a-primed neutrophils for ANCA-mediated activation.

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Title: Cycling of Etk and Etp phosphorylation states is involved in formation of group 4 capsule by Escherichia coli.

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Title: RGS Proteins in Heart: Brakes on the Vagus.

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Title: Antihyperglycemic effect of Annona squamosa hexane extract in type 2 diabetes animal model: PTP1B inhibition, a possible mechanism of action?

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Title: A highly scalable peptide-based assay system for proteomics.

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Title: GEP100/Arf6 is required for epidermal growth factor-induced ERK/Rac1 signaling and cell migration in human hepatoma HepG2 cells.

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Title: Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death.

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Title: Signaling for death: tyrosine phosphorylation in the response to glucose deprivation.

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Title: Cortactin is involved in the entry of Coxiella burnetii into non-phagocytic cells.

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Title: Cell invasion by Neisseria meningitidis requires a functional interplay between the focal adhesion kinase, Src and cortactin.

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Title: Podosomes in migrating microglia: components and matrix degradation.

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Title: Carboxyamidotriazole-orotate inhibits the growth of imatinib-resistant chronic myeloid leukaemia cells and modulates exosomes-stimulated angiogenesis.

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Title: Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation.

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Title: Tyrosine Phosphorylation of the BRI1 Receptor Kinase Occurs via a Post-Translational Modification and is Activated by the Juxtamembrane Domain.

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Title: Fc gamma receptor CD64 modulates the inhibitory activity of infliximab.

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Title: Cortactin as a target for FAK in the regulation of focal adhesion dynamics.

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Title: Cortactin is a substrate of activated Cdc42-associated kinase 1 (ACK1) during ligand-induced epidermal growth factor receptor downregulation.

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Title: Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors.

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Title: HCV NS5A protein containing potential ligands for both Src homology 2 and 3 domains enhances autophosphorylation of Src family kinase Fyn in B cells.

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Title: EphrinA1-EphA2 signal induces compaction and polarization of Madin-Darby canine kidney cells by inactivating Ezrin through negative regulation of RhoA.

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Title: Comparative proteomics and phosphoproteomics analyses of DHEA-induced on hepatic lipid metabolism in broiler chickens.

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Title: Interleukin-2 signaling pathway analysis by quantitative phosphoproteomics.

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Title: MAPKKK-independent regulation of the Hog1 stress-activated protein kinase in Candida albicans.

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Title: Comparison of three quantitative phosphoproteomic strategies to study receptor tyrosine kinase signaling.

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Title: Impaired Rho GTPase activation abrogates cell polarization and migration in macrophages with defective lipolysis.

Journal: Cellular and molecular life sciences : CMLS 20111201

Title: Synthetic osteogenic growth peptide promotes differentiation of human bone marrow mesenchymal stem cells to osteoblasts via RhoA/ROCK pathway.

Journal: Molecular and cellular biochemistry 20111201

Title: Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiation.

Journal: The Journal of investigative dermatology 20111201

Title: MICALs in control of the cytoskeleton, exocytosis, and cell death.

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Title: Recent patents related to phosphorylation signaling pathway on cancer.

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Title: PKCβ-dependent phosphorylation of the glycine transporter 1.

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Title: Mediators of the Jak/STAT signaling pathway in human spermatozoa.

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Title: Neuronal Shc: a gene of longevity in the brain?

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Title: Evaluation of HCD- and CID-type fragmentation within their respective detection platforms for murine phosphoproteomics.

Journal: Molecular & cellular proteomics : MCP 20111201

Title: Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa.

Journal: Human reproduction (Oxford, England) 20111201

Title: Discrimination between peptide O-sulfo- and O-phosphotyrosine residues by negative ion mode electrospray tandem mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry 20111201

Title: SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20111201

Title: Lyn is a redox sensor that mediates leukocyte wound attraction in vivo.

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Title: Pillars article: Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science. 1992. 257: 809-813.

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Title: Intraspecific and interspecific interactions among proteins regulating exopolysaccharide synthesis in Streptococcus thermophilus, Streptococcus iniae, and Lactococcus lactis subsp. cremoris and the assessment of potential lateral gene transfer.

Journal: Canadian journal of microbiology 20111201

Title: The human cytomegalovirus UL11 protein interacts with the receptor tyrosine phosphatase CD45, resulting in functional paralysis of T cells.

Journal: PLoS pathogens 20111201

Title: PIM kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer cells.

Journal: Oncotarget 20111201

Title: Phosphatase inhibitor, sodium stibogluconate, in combination with interferon (IFN) alpha 2b: phase I trials to identify pharmacodynamic and clinical effects.

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Title: Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin.

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Title: Identification of MET and SRC activation in melanoma cell lines showing primary resistance to PLX4032.

Journal: Neoplasia (New York, N.Y.) 20111201

Title: Duox, Flotillin-2, and Src42A are required to activate or delimit the spread of the transcriptional response to epidermal wounds in Drosophila.

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Title: AHI-1: a novel signaling protein and potential therapeutic target in human leukemia and brain disorders.

Journal: Oncotarget 20111201

Title: [Regulation of hepatic lipid metabolism by adiponectin via IRS-2 phosphorylation in OLETF rats].

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Title: Tyrosine phosphorylation as a conformational switch: a case study of integrin β3 cytoplasmic tail.

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Title: Dynamic substrate enhancement for the identification of specific, second-site-binding fragments targeting a set of protein tyrosine phosphatases.

Journal: Chembiochem : a European journal of chemical biology 20111125

Title: Conformational basis for substrate recruitment in protein tyrosine phosphatase 10D.

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Title: Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling.

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Title: Form of dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A nonphosphorylated at tyrosine 145 and 147 is enriched in the nuclei of astroglial cells, adult hippocampal progenitors, and some cholinergic axon terminals.

Journal: Neuroscience 20111110

Title: Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma through upregulation of FAK and Src.

Journal: The Journal of investigative dermatology 20111101

Title: Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways.

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Title: IgA1 immune complexes from pediatric patients with IgA nephropathy activate cultured human mesangial cells.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111101

Title: RF1 knockout allows ribosomal incorporation of unnatural amino acids at multiple sites.

Journal: Nature chemical biology 20111101

Title: Simultaneous identification of tyrosine phosphorylation and sulfation sites utilizing tyrosine-specific bromination.

Journal: Journal of the American Society for Mass Spectrometry 20111101

Title: The JAK-STAT pathway controls Plasmodium vivax load in early stages of Anopheles aquasalis infection.

Journal: PLoS neglected tropical diseases 20111101

Title: Murid herpesvirus-4 exploits dendritic cells to infect B cells.

Journal: PLoS pathogens 20111101

Title: Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells.

Journal: Oncotarget 20111101

Title: Mutations of TFAP2B in congenital heart disease patients in Mysore, South India.

Journal: The Indian journal of medical research 20111101

Title: Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations.

Journal: Open biology 20111101

Title: Consensus substrate sequence for protein-tyrosine phosphatase receptor type Z.

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Title: A self-immobilizing and fluorogenic unnatural amino acid that mimics phosphotyrosine.

Journal: Chemical communications (Cambridge, England) 20111021

Title: Impact of epididymal maturation, ejaculation and in vitro capacitation on tyrosine phosphorylation patterns exhibited of boar (Sus domesticus) spermatozoa.

Journal: Theriogenology 20111015

Title: Rapid and reproducible single-stage phosphopeptide enrichment of complex peptide mixtures: application to general and phosphotyrosine-specific phosphoproteomics experiments.

Journal: Analytical chemistry 20111015

Title: Myeloid differentiation factor-2 interacts with Lyn kinase and is tyrosine phosphorylated following lipopolysaccharide-induced activation of the TLR4 signaling pathway.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20111015

Title: Structure and substrate recognition of the Staphylococcus aureus protein tyrosine phosphatase PtpA.

Journal: Journal of molecular biology 20111014

Title: Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis.

Journal: Cell 20111014

Title: Comparative properties of caveolar and noncaveolar preparations of kidney Na+/K+-ATPase.

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Title: A phosphoarginine containing peptide as an artificial SH2 ligand.

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Title: Phosphoproteomic mass spectrometry profiling links Src family kinases to escape from HER2 tyrosine kinase inhibition.

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Title: Functional and molecular interactions between Rac1 and FE65.

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Title: 1H, 13C and 15N backbone and side-chain chemical shift assignment of the Fyn SH2 domain and its complex with a phosphotyrosine peptide.

Journal: Biomolecular NMR assignments 20111001

Title: The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling.

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Title: Mapping protein interactions by combining antibody affinity maturation and mass spectrometry.

Journal: Analytical biochemistry 20111001

Title: Attachment of HeLa cells during early G1 phase.

Journal: Histochemistry and cell biology 20111001

Title: APPL1 mediates adiponectin-induced LKB1 cytosolic localization through the PP2A-PKCzeta signaling pathway.

Journal: Molecular endocrinology (Baltimore, Md.) 20111001

Title: Pleiotropic functions of EAPII/TTRAP/TDP2: cancer development, chemoresistance and beyond.

Journal: Cell cycle (Georgetown, Tex.) 20111001

Title: Chlamydia trachomatis co-opts the FGF2 signaling pathway to enhance infection.

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Title: Potentiation of Helicobacter pylori CagA protein virulence through homodimerization.

Journal: The Journal of biological chemistry 20110923

Title: Focal adhesion kinase promotes integrin adhesion dynamics necessary for chemotropic turning of nerve growth cones.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110921

Title: NADPH-oxidase-dependent reactive oxygen species mediate EGFR transactivation by FPRL1 in WKYMVm-stimulated human lung cancer cells.

Journal: Free radical biology & medicine 20110915

Title: Diagnostic cyclisation reactions which follow phosphate transfer to carboxylate anion centres for energised [M-H]- anions of pTyr-containing peptides.

Journal: Rapid communications in mass spectrometry : RCM 20110915

Title: Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain.

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Title: Secretome compartment is a valuable source of biomarkers for cancer-relevant pathways.

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Title: MEMO associated with an ErbB2 receptor phosphopeptide reveals a new phosphotyrosine motif.

Journal: FEBS letters 20110902

Title: Rapid phospho-turnover by receptor tyrosine kinases impacts downstream signaling and drug binding.

Journal: Molecular cell 20110902

Title: Integrin-associated tyrosine kinase FAK affects Cbfa1 expression.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20110901

Title: Dual-specificity phosphatase DUSP6 has tumor-promoting properties in human glioblastomas.

Journal: Oncogene 20110901

Title: Influence of insulin on glutamine synthetase in the Müller glial cells of retina.

Journal: Metabolic brain disease 20110901

Title: Progesterone synthesis by human placental mitochondria is sensitive to PKA inhibition by H89.

Journal: The international journal of biochemistry & cell biology 20110901

Title: PAK1-Nck regulates cyclin D1 promoter activity in response to prolactin.

Journal: Molecular endocrinology (Baltimore, Md.) 20110901

Title: IGF-I stimulates cooperative interaction between the IGF-I receptor and CSK homologous kinase that regulates SHPS-1 phosphorylation in vascular smooth muscle cells.

Journal: Molecular endocrinology (Baltimore, Md.) 20110901

Title: The p75 receptor mediates axon growth inhibition through an association with PIR-B.

Journal: Cell death & disease 20110901

Title: Helicobacter pylori exploits a unique repertoire of type IV secretion system components for pilus assembly at the bacteria-host cell interface.

Journal: PLoS pathogens 20110901

Title: Restoration of IFNγR subunit assembly, IFNγ signaling and parasite clearance in Leishmania donovani infected macrophages: role of membrane cholesterol.

Journal: PLoS pathogens 20110901

Title: Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control.

Journal: PLoS pathogens 20110901

Title: ESRRA-C11orf20 is a recurrent gene fusion in serous ovarian carcinoma.

Journal: PLoS biology 20110901

Title: Quantitative in vivo analyses reveal calcium-dependent phosphorylation sites and identifies a novel component of the Toxoplasma invasion motor complex.

Journal: PLoS pathogens 20110901

Title: Epidermal growth factor receptor signalling contributes to osteoblastic stromal cell proliferation, osteoclastogenesis and disease progression in giant cell tumour of bone.

Journal: Histopathology 20110901

Title: The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85.

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Title: Correlation between the destruction of tight junction by patulin treatment and increase of phosphorylation of ZO-1 in Caco-2 human colon cancer cells.

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Title: Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding.

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Title: Cyclin-dependent kinase 1 (CDK1)-mediated phosphorylation of enhancer of zeste 2 (Ezh2) regulates its stability.

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Title: Discrimination between 5-hydroxymethylcytosine and 5-methylcytosine by a chemically designed peptide.

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Title: Excitation-transcription coupling in skeletal muscle: the molecular pathways of exercise.

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Title: Characterization of a TiO₂ enrichment method for label-free quantitative phosphoproteomics.

Journal: Methods (San Diego, Calif.) 20110801

Title: Toward a comprehensive characterization of the phosphotyrosine proteome.

Journal: Cellular signalling 20110801

Title: SH2B1β regulates N-cadherin levels, cell-cell adhesion and nerve growth factor-induced neurite initiation.

Journal: Journal of cellular physiology 20110801

Title: Increased abundance of the adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif (APPL1) in patients with obesity and type 2 diabetes: evidence for altered adiponectin signalling.

Journal: Diabetologia 20110801

Title: Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice.

Journal: Diabetologia 20110801

Title: Antagonism of the Stat3-Stat3 protein dimer with salicylic acid based small molecules.

Journal: ChemMedChem 20110801

Title: TLRs innate immunereceptors and Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) CIDR1α-driven human polyclonal B-cell activation.

Journal: Acta tropica 20110801

Title: Nucleocytoplasmic transfer of cyclin dependent kinase 5 and its binding to puromycin-sensitive aminopeptidase in Dictyostelium discoideum.

Journal: Histochemistry and cell biology 20110801

Title: Cytoskeletal polarity mediates localized induction of the heart progenitor lineage.

Journal: Nature cell biology 20110801

Title: Integrating signals from the T-cell receptor and the interleukin-2 receptor.

Journal: PLoS computational biology 20110801

Title: A transient increase in total head phosphotyrosine levels is observed upon the emergence of Aedes aegypti from the pupal stage.

Journal: Memorias do Instituto Oswaldo Cruz 20110801

Title: Focal adhesion proteins talin-1 and vinculin negatively affect paxillin phosphorylation and limit retroviral infection.

Journal: Journal of molecular biology 20110729

Title: Protein interactions among Fe65, the low-density lipoprotein receptor-related protein, and the amyloid precursor protein.

Journal: Biochemistry 20110719

Title: ADP-ribosylation of arginine.

Journal: Amino acids 20110701

Title: Phosphoproteomics perspective on plant signal transduction and tyrosine phosphorylation.

Journal: Phytochemistry 20110701

Title: Tyrosine phosphorylation of actin during microcyst formation and germination in Polysphondylium pallidum.

Journal: Protist 20110701

Title: Acetylome and phosphoproteome modifications in imatinib resistant chronic myeloid leukaemia cells treated with valproic acid.

Journal: Leukemia research 20110701

Title: Thrombospondin-1 opens the paracellular pathway in pulmonary microvascular endothelia through EGFR/ErbB2 activation.

Journal: American journal of physiology. Lung cellular and molecular physiology 20110701

Title: Specificity of HCPTP variants toward EphA2 tyrosines by quantitative selected reaction monitoring.

Journal: Protein science : a publication of the Protein Society 20110701

Title: TTBK2 kinase substrate specificity and the impact of spinocerebellar-ataxia-causing mutations on expression, activity, localization and development.

Journal: The Biochemical journal 20110701

Title: Quantitative phospho-proteomic profiling of hepatocyte growth factor (HGF)-MET signaling in colorectal cancer.

Journal: Journal of proteome research 20110701

Title: Vav1 is a crucial molecule in monocytic/macrophagic differentiation of myeloid leukemia-derived cells.

Journal: Cell and tissue research 20110701

Title: Targeting invadopodia to block breast cancer metastasis.

Journal: Oncotarget 20110701

Title: Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148.

Journal: The Journal of biological chemistry 20110624

Title: Phospholipase C-β3 regulates FcɛRI-mediated mast cell activation by recruiting the protein phosphatase SHP-1.

Journal: Immunity 20110624

Title: Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110620

Title: Particle stimulation dephosphorylates glutathione S-transferase π1 of epithelial cells.

Journal: Toxicology 20110618

Title: PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer.

Journal: Oncogene 20110602

Title: Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation.

Journal: Blood 20110602

Title: Analysis of dynamic tyrosine phosphoproteome in LFA-1 triggered migrating T-cells.

Journal: Journal of cellular physiology 20110601

Title: Antibody-free peptide substrate screening of serine/threonine kinase (protein kinase A) with a biotinylated detection probe.

Journal: Analytical biochemistry 20110601

Title: Identification of Dermcidin as a novel binding protein of Nck1 and characterization of its role in promoting cell migration.

Journal: Biochimica et biophysica acta 20110601

Title: Rin-like, a novel regulator of endocytosis, acts as guanine nucleotide exchange factor for Rab5a and Rab22.

Journal: Biochimica et biophysica acta 20110601

Title: Protein tyrosine phosphorylation and zona binding ability of in vitro capacitated and cryopreserved buffalo spermatozoa.

Journal: Theriogenology 20110601

Title: Characterization and role of NUMB in the human extravillous trophopblast.

Journal: Placenta 20110601

Title: Tensin2 is a novel mediator in thrombopoietin (TPO)-induced cellular proliferation by promoting Akt signaling.

Journal: Cell cycle (Georgetown, Tex.) 20110601

Title: Eukaryotic-like Ser/Thr protein kinases SpkC/F/K are involved in phosphorylation of GroES in the Cyanobacterium synechocystis.

Journal: DNA research : an international journal for rapid publication of reports on genes and genomes 20110601

Title: Urban PM2.5 induces ROS generation and RBC damage in COPD patients.

Journal: Frontiers in bioscience (Elite edition) 20110601

Title: Metabolism and brain cancer.

Journal: Clinics (Sao Paulo, Brazil) 20110601

Title: Identification of nitrotyrosine containing peptides using combined fractional diagonal chromatography (COFRADIC) and off-line nano-LC-MALDI.

Journal: Journal of the American Society for Mass Spectrometry 20110601

Title: The strictly conserved Arg-321 residue in the active site of Escherichia coli topoisomerase I plays a critical role in DNA rejoining.

Journal: The Journal of biological chemistry 20110527

Title: Potent and selective phosphopeptide mimetic prodrugs targeted to the Src homology 2 (SH2) domain of signal transducer and activator of transcription 3.

Journal: Journal of medicinal chemistry 20110526

Title: Role of β-Pix in corneal epithelial cell migration on fibronectin.

Journal: Investigative ophthalmology & visual science 20110516

Title: A Dictyostelium SH2 adaptor protein required for correct DIF-1 signaling and pattern formation.

Journal: Developmental biology 20110515

Title: Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain.

Journal: Journal of molecular biology 20110513

Title: Structure analysis of the Staphylococcus aureus UDP-N-acetyl-mannosamine dehydrogenase Cap5O involved in capsular polysaccharide biosynthesis.

Journal: The Journal of biological chemistry 20110513

Title: AS160 phosphotyrosine-binding domain constructs inhibit insulin-stimulated GLUT4 vesicle fusion with the plasma membrane.

Journal: The Journal of biological chemistry 20110513

Title: Focal adhesion kinase (FAK) binds RET kinase via its FERM domain, priming a direct and reciprocal RET-FAK transactivation mechanism.

Journal: The Journal of biological chemistry 20110513

Title: hTID-1 defines a novel regulator of c-Met Receptor signaling in renal cell carcinomas.

Journal: Oncogene 20110512

Title: Physiopathological function of hematoside (GM3 ganglioside).

Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110511

Title: A role for nucleotides in support of breast cancer angiogenesis: heterologous receptor signalling.

Journal: British journal of cancer 20110510

Title: Optimization of immunoaffinity enrichment and detection: toward a comprehensive characterization of the phosphotyrosine proteome of K562 cells by liquid chromatography-mass spectrometry.

Journal: The Analyst 20110507

Title: Mitogen-activated protein kinase (MAPK) phosphatase 3-mediated cross-talk between MAPKs ERK2 and p38alpha.

Journal: The Journal of biological chemistry 20110506

Title: The metalloprotease, NN-PF3 from Naja naja venom inhibits platelet aggregation primarily by affecting α2β1 integrin.

Journal: Annals of hematology 20110501

Title: Accreta complicating complete placenta previa is characterized by reduced systemic levels of vascular endothelial growth factor and by epithelial-to-mesenchymal transition of the invasive trophoblast.

Journal: American journal of obstetrics and gynecology 20110501

Title: The integrin-binding motif RGDS induces protein tyrosine phosphorylation without activation in Bufo arenarum (Amphibia) oocytes.

Journal: Reproduction (Cambridge, England) 20110501

Title: Density of human bone marrow stromal cells regulates commitment to vascular lineages.

Journal: Stem cell research 20110501

Title: Ablation of PI3K p110-α prevents high-fat diet-induced liver steatosis.

Journal: Diabetes 20110501

Title: Genetic ablation of cGMP-dependent protein kinase type I causes liver inflammation and fasting hyperglycemia.

Journal: Diabetes 20110501

Title: Nobiletin attenuates VLDL overproduction, dyslipidemia, and atherosclerosis in mice with diet-induced insulin resistance.

Journal: Diabetes 20110501

Title: Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity.

Journal: Oncotarget 20110501

Title: [Adiponectin decreases insulin receptor substrate-1 phosphorylation in the liver of OLETF rats possibly through nuclear factor-κB signaling pathway].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110501

Title: Phosphopeptides designed for 5-methylcytosine recognition.

Journal: Biochemistry 20110426

Title: Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia.

Journal: The Journal of biological chemistry 20110422

Title: Separation of phosphorylated peptides utilizing dual pH- and temperature-responsive chromatography.

Journal: Journal of chromatography. A 20110415

Title: Disassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosis.

Journal: Experimental cell research 20110415

Title: Interactions between GIPC-APPL and GIPC-TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes.

Journal: Archives of biochemistry and biophysics 20110415

Title: Trask phosphorylation defines the reverse mode of a phosphotyrosine signaling switch that underlies cell anchorage state.

Journal: Cell cycle (Georgetown, Tex.) 20110415

Title: Tyrosine phosphorylation modulates store-operated calcium entry in cultured rat epididymal basal cells.

Journal: Journal of cellular physiology 20110401

Title: Differential G-protein-coupled receptor phosphorylation provides evidence for a signaling bar code.

Journal: The Journal of biological chemistry 20110401

Title: Effects of the plasmid-encoded toxin of enteroaggregative Escherichia coli on focal adhesion complexes.

Journal: FEMS immunology and medical microbiology 20110401

Title: Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment.

Journal: Biochimica et biophysica acta 20110401

Title: The adapter protein APPL1 links FSH receptor to inositol 1,4,5-trisphosphate production and is implicated in intracellular Ca(2+) mobilization.

Journal: Endocrinology 20110401

Title: Novel fat depot-specific mechanisms underlie resistance to visceral obesity and inflammation in 11 β-hydroxysteroid dehydrogenase type 1-deficient mice.

Journal: Diabetes 20110401

Title: Intracellular trafficking considerations in the development of natural ligand-drug molecular conjugates for cancer.

Journal: Annals of biomedical engineering 20110401

Title: Focal adhesion remodeling is crucial for glucose-stimulated insulin secretion and involves activation of focal adhesion kinase and paxillin.

Journal: Diabetes 20110401

Title: Phosphoproteome analysis of the pathogenic bacterium Helicobacter pylori reveals over-representation of tyrosine phosphorylation and multiply phosphorylated proteins.

Journal: Proteomics 20110401

Title: Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling.

Journal: Cellular oncology (Dordrecht) 20110401

Title: Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

Journal: Nature cell biology 20110401

Title: Protein tyrosine phosphatase assays.

Journal: Current protocols in immunology 20110401

Title: Association of PTPN22 1858T/T genotype with type 1 diabetes, Graves' disease but not with rheumatoid arthritis in Russian population.

Journal: Aging 20110401

Title: Reversing B cell aging.

Journal: Aging 20110401

Title: The MARCH family E3 ubiquitin ligase K5 alters monocyte metabolism and proliferation through receptor tyrosine kinase modulation.

Journal: PLoS pathogens 20110401

Title: Phosphorylation-dependent differential regulation of plant growth, cell death, and innate immunity by the regulatory receptor-like kinase BAK1.

Journal: PLoS genetics 20110401

Title: Substrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2.

Journal: Biochemistry 20110329

Title: ARAP3 inhibits peritoneal dissemination of scirrhous gastric carcinoma cells by regulating cell adhesion and invasion.

Journal: Oncogene 20110324

Title: Identification and functional analysis of a new phosphorylation site (Y398) in the SH3 domain of Abi-1.

Journal: FEBS letters 20110323

Title: Antitumor activity of BIBF 1120, a triple angiokinase inhibitor, and use of VEGFR2+pTyr+ peripheral blood leukocytes as a pharmacodynamic biomarker in vivo.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110315

Title: T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component.

Journal: The Journal of biological chemistry 20110304

Title: The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions.

Journal: The Journal of biological chemistry 20110304

Title: Analysis of phosphotyrosine signaling in glioblastoma identifies STAT5 as a novel downstream target of ΔEGFR.

Journal: Journal of proteome research 20110304

Title: Identification of phosphoproteins associated with human neutrophil granules following chemotactic peptide stimulation.

Journal: Molecular & cellular proteomics : MCP 20110301

Title: Integration of proteomic analyses to monitor the activity status of phosphorylation signaling.

Journal: Journal of proteomics 20110301

Title: Globular and full-length adiponectin induce NO-dependent vasodilation in resistance arteries of Zucker lean but not Zucker diabetic fatty rats.

Journal: American journal of hypertension 20110301

Title: Proteomic analysis of HIV-infected macrophages.

Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20110301

Title: Protein-protein interactions among the components of the biosynthetic machinery responsible for exopolysaccharide production in Streptococcus thermophilus MR-1C.

Journal: Journal of applied microbiology 20110301

Title: Suppressor of cytokine signaling 1 interacts with oncogenic lymphocyte-specific protein tyrosine kinase.

Journal: Oncology reports 20110301

Title: Rapid analysis of phosphoamino acids from phosvitin by near-infrared cyanine 1-(ε-succinimydyl-hexanoate)-1'-methyl-3,3,3',3'-tetramethyl-indocarbocyanine-5,5'-disulfonate potassium derivatization and polyacrylamide-coated CE with LIF detection.

Journal: Electrophoresis 20110301

Title: CAERUS: predicting CAncER oUtcomeS using relationship between protein structural information, protein networks, gene expression data, and mutation data.

Journal: PLoS computational biology 20110301

Title: Identifying changes in the synaptic proteome of cirrhotic alcoholic superior frontal gyrus.

Journal: Current neuropharmacology 20110301

Title: Dyrk1A Positively Stimulates ASK1-JNK Signaling Pathway during Apoptotic Cell Death.

Journal: Experimental neurobiology 20110301

Title: Syk-dependent phosphorylation of CLEC-2: a novel mechanism of hem-immunoreceptor tyrosine-based activation motif signaling.

Journal: The Journal of biological chemistry 20110211

Title: Identification of new substrates of the protein-tyrosine phosphatase PTP1B by Bayesian integration of proteome evidence.

Journal: The Journal of biological chemistry 20110211

Title: Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells.

Journal: The Journal of biological chemistry 20110211

Title: Proteomic characterization of plasma membrane-proximal T cell activation responses.

Journal: The Journal of biological chemistry 20110211

Title: Mechanistic studies of Ser/Thr dehydration catalyzed by a member of the LanL lanthionine synthetase family.

Journal: Biochemistry 20110208

Title: Cross-correlated fluctuation analysis reveals phosphorylation-regulated paxillin-FAK complexes in nascent adhesions.

Journal: Biophysical journal 20110202

Title: mTOR partly mediates insulin resistance by phosphorylation of insulin receptor substrate-1 on serine(307) residues after burn.

Journal: Burns : journal of the International Society for Burn Injuries 20110201

Title: Beta-carotene affects gene expression in lungs of male and female Bcmo1 (-/-) mice in opposite directions.

Journal: Cellular and molecular life sciences : CMLS 20110201

Title: In-silico characterization of the effects of phosphorylated tyrosines 86 and 106 on structure and binding of MAL: insight into hyperinflammatory response to infection by the human malaria parasites.

Journal: Journal of receptor and signal transduction research 20110201

Title: Arsenic stress activates MAP kinase in rice roots and leaves.

Journal: Archives of biochemistry and biophysics 20110201

Title: Molecular pharmacology in a simple model system: implicating MAP kinase and phosphoinositide signalling in bipolar disorder.

Journal: Seminars in cell & developmental biology 20110201

Title: ABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1.

Journal: Leukemia 20110201

Title: Receptor tyrosine phosphatase PTPγ is a regulator of spinal cord neurogenesis.

Journal: Molecular and cellular neurosciences 20110201

Title: A systems view of epithelial-mesenchymal transition signaling states.

Journal: Clinical & experimental metastasis 20110201

Title: Parallel evolution of a type IV secretion system in radiating lineages of the host-restricted bacterial pathogen Bartonella.

Journal: PLoS genetics 20110201

Title: Autoimmune hypoglycemia in a patient with characterization of insulin receptor autoantibodies.

Journal: Diabetes & metabolism journal 20110201

Title: Andrographolide attenuates tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes.

Journal: Molecular and cellular endocrinology 20110130

Title: Leptin receptor activation increases Sam68 tyrosine phosphorylation and expression in human trophoblastic cells.

Journal: Molecular and cellular endocrinology 20110130

Title: The ShcA phosphotyrosine docking protein uses distinct mechanisms to regulate myocyte and global heart function.

Journal: Circulation research 20110121

Title: An adjacent arginine, and the phosphorylated tyrosine in the c-Met receptor target sequence, dictates the orientation of c-Cbl binding.

Journal: FEBS letters 20110121

Title: Shp2 protein tyrosine phosphatase inhibitor activity of estramustine phosphate and its triterpenoid analogs.

Journal: Bioorganic & medicinal chemistry letters 20110115

Title: A CSF-1 receptor phosphotyrosine 559 signaling pathway regulates receptor ubiquitination and tyrosine phosphorylation.

Journal: The Journal of biological chemistry 20110114

Title: Regulated phosphorylation of a major UDP-glucuronosyltransferase isozyme by tyrosine kinases dictates endogenous substrate selection for detoxification.

Journal: The Journal of biological chemistry 20110114

Title: Primary tumor xenografts of human lung adeno and squamous cell carcinoma express distinct proteomic signatures.

Journal: Journal of proteome research 20110107

Title: Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration.

Journal: The Journal of biological chemistry 20110107

Title: Negative regulation of TGFβ signaling by the kinase LKB1 and the scaffolding protein LIP1.

Journal: The Journal of biological chemistry 20110107

Title: TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage.

Journal: The Journal of biological chemistry 20110107

Title: Proteomic analysis of native hepatocyte nuclear factor-4α (HNF4α) isoforms, phosphorylation status, and interactive cofactors.

Journal: The Journal of biological chemistry 20110107

Title: α-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways.

Journal: British journal of cancer 20110104

Title: Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo.

Journal: British journal of cancer 20110104

Title: A Chinese Herbal Decoction, Dang Gui Bu Xue Tang, Prepared from Radix Astragali and Radix Angelicae sinensis, Ameliorates Insulin Resistance Induced by A High-Fructose Diet in Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Suppression of Heregulin-β1/HER2-Modulated Invasive and Aggressive Phenotype of Breast Carcinoma by Pterostilbene via Inhibition of Matrix Metalloproteinase-9, p38 Kinase Cascade and Akt Activation.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: The interaction of Jagged-1 cytoplasmic tail with afadin PDZ domain is local, folding-independent, and tuned by phosphorylation.

Journal: Journal of molecular recognition : JMR 20110101

Title: Grb7 binds to Hax-1 and undergoes an intramolecular domain association that offers a model for Grb7 regulation.

Journal: Journal of molecular recognition : JMR 20110101

Title: Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes.

Journal: Molecular & cellular proteomics : MCP 20110101

Title: Prep1 controls insulin glucoregulatory function in liver by transcriptional targeting of SHP1 tyrosine phosphatase.

Journal: Diabetes 20110101

Title: Cloning, sequence identification, and tissue expression analysis of novel chicken NYGGF4 gene.

Journal: Molecular and cellular biochemistry 20110101

Title: Serine residues in the LAT adaptor are essential for TCR-dependent signal transduction.

Journal: Journal of leukocyte biology 20110101

Title: Ciona intestinalis Noto4 contains a phosphotyrosine interaction domain and is involved in the midline intercalation of notochord cells.

Journal: The International journal of developmental biology 20110101

Title: Collagen binding specificity of the discoidin domain receptors: binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1.

Journal: Matrix biology : journal of the International Society for Matrix Biology 20110101

Title: Osmotic stress stimulates phosphorylation and cellular expression of heat shock proteins in rhesus macaque sperm.

Journal: Journal of andrology 20110101

Title: Light-induced phosphorylation of crystallins in the retinal pigment epithelium.

Journal: International journal of biological macromolecules 20110101

Title: Design and NMR studies of cyclic peptides targeting the N-terminal domain of the protein tyrosine phosphatase YopH.

Journal: Chemical biology & drug design 20110101

Title: A fluorescence lifetime-based assay for abelson kinase.

Journal: Journal of biomolecular screening 20110101

Title: EGFR activation monitored by SW-FCCS in live cells.

Journal: Frontiers in bioscience (Elite edition) 20110101

Title: Inhibition of Epidermal Growth Factor Receptor and PI3K/Akt Signaling Suppresses Cell Proliferation and Survival through Regulation of Stat3 Activation in Human Cutaneous Squamous Cell Carcinoma.

Journal: Journal of skin cancer 20110101

Title: Loss of function of e-cadherin in embryonic stem cells and the relevance to models of tumorigenesis.

Journal: Journal of oncology 20110101

Title: APP processing in Alzheimer's disease.

Journal: Molecular brain 20110101

Title: Shb deficient mice display an augmented TH2 response in peripheral CD4+ T cells.

Journal: BMC immunology 20110101

Title: Optimization of peptide density on microarray surface for quantitative phosphoproteomics.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20110101

Title: Proteomic snapshot of the EGF-induced ubiquitin network.

Journal: Molecular systems biology 20110101

Title: Radiation rescue: mesenchymal stromal cells protect from lethal irradiation.

Journal: PloS one 20110101

Title: Irreversible AE1 tyrosine phosphorylation leads to membrane vesiculation in G6PD deficient red cells.

Journal: PloS one 20110101

Title: Bim and Mcl-1 exert key roles in regulating JAK2V617F cell survival.

Journal: BMC cancer 20110101

Title: Escharectomy and allografting during shock stage reduces insulin resistance induced by major burn.

Journal: Journal of burn care & research : official publication of the American Burn Association 20110101

Title: Biofilm development on Caenorhabditis elegans by Yersinia is facilitated by quorum sensing-dependent repression of type III secretion.

Journal: PLoS pathogens 20110101

Title: Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma.

Journal: PloS one 20110101

Title: Morphological and molecular alterations in 1,2 dimethylhydrazine and azoxymethane induced colon carcinogenesis in rats.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Reverse transcription of the pFOXC mitochondrial retroplasmids of Fusarium oxysporum is protein primed.

Journal: Mobile DNA 20110101

Title: Repetitive peroxide exposure reveals pleiotropic mitogen-activated protein kinase signaling mechanisms.

Journal: Journal of signal transduction 20110101

Title: Issues associated with the use of phosphospecific antibodies to localise active and inactive pools of GSK-3 in cells.

Journal: Biology direct 20110101

Title: Phosphoproteomics characterization of novel phosphorylated sites of lens proteins from normal and cataractous human eye lenses.

Journal: Molecular vision 20110101

Title: High- and low-affinity epidermal growth factor receptor-ligand interactions activate distinct signaling pathways.

Journal: PloS one 20110101

Title: Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system.

Journal: PLoS biology 20110101

Title: Tyrosine phosphorylation of tau by the SRC family kinases lck and fyn.

Journal: Molecular neurodegeneration 20110101

Title: Identification of ligand binding sites of proteins using the Gaussian Network Model.

Journal: PloS one 20110101

Title: Activation of MyD88 signaling upon staphylococcal enterotoxin binding to MHC class II molecules.

Journal: PloS one 20110101

Title: Hierarchical graphs for rule-based modeling of biochemical systems.

Journal: BMC bioinformatics 20110101

Title: Differential gene expression in liver and small intestine from lactating rats compared to age-matched virgin controls detects increased mRNA of cholesterol biosynthetic genes.

Journal: BMC genomics 20110101

Title: Protein S blocks the extrinsic apoptotic cascade in tissue plasminogen activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1 signaling pathway.

Journal: Molecular neurodegeneration 20110101

Title: Inhibition of RhoA GTPase and the subsequent activation of PTP1B protects cultured hippocampal neurons against amyloid β toxicity.

Journal: Molecular neurodegeneration 20110101

Title: Identification of alternatively spliced Dab1 and Fyn isoforms in pig.

Journal: BMC neuroscience 20110101

Title: Maternal genome-wide DNA methylation patterns and congenital heart defects.

Journal: PloS one 20110101

Title: Profiling the HER3/PI3K pathway in breast tumors using proximity-directed assays identifies correlations between protein complexes and phosphoproteins.

Journal: PloS one 20110101

Title: A novel soluble immune-type receptor (SITR) in teleost fish: carp SITR is involved in the nitric oxide-mediated response to a protozoan parasite.

Journal: PloS one 20110101

Title: Regulation of brown fat adipogenesis by protein tyrosine phosphatase 1B.

Journal: PloS one 20110101

Title: Epidermal growth factor receptor mutation in combination with expression of MIG6 alters gefitinib sensitivity.

Journal: BMC systems biology 20110101

Title: Interplay between kinase domain autophosphorylation and F-actin binding domain in regulating imatinib sensitivity and nuclear import of BCR-ABL.

Journal: PloS one 20110101

Title: Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation.

Journal: PloS one 20110101

Title: The RACK1 signaling scaffold protein selectively interacts with Yersinia pseudotuberculosis virulence function.

Journal: PloS one 20110101

Title: Two TPX2-dependent switches control the activity of Aurora A.

Journal: PloS one 20110101

Title: Jak2 is a negative regulator of ubiquitin-dependent endocytosis of the growth hormone receptor.

Journal: PloS one 20110101

Title: Changes in expression of VE-cadherin and MMPs in endothelial cells: Implications for angiogenesis.

Journal: Vascular cell 20110101

Title: Biosynthesis of Silver Nanoparticles from Desmodium triflorum: A Novel Approach Towards Weed Utilization.

Journal: Biotechnology research international 20110101

Title: A Boolean-based systems biology approach to predict novel genes associated with cancer: Application to colorectal cancer.

Journal: BMC systems biology 20110101

Title: δ-Tocotrienol and quercetin reduce serum levels of nitric oxide and lipid parameters in female chickens.

Journal: Lipids in health and disease 20110101

Title: An unexpected role for the clock protein timeless in developmental apoptosis.

Journal: PloS one 20110101

Title: Exploring the evolutionary relationship of insulin receptor substrate family using computational biology.

Journal: PloS one 20110101

Title: Sprouty2 and Spred1-2 proteins inhibit the activation of the ERK pathway elicited by cyclopentenone prostanoids.

Journal: PloS one 20110101

Title: Functional characterization of human cancer-derived TRKB mutations.

Journal: PloS one 20110101

Title: Difluoromethylornithine is a novel inhibitor of Helicobacter pylori growth, CagA translocation, and interleukin-8 induction.

Journal: PloS one 20110101

Title: Changes in gene expression and cellular architecture in an ovarian cancer progression model.

Journal: PloS one 20110101

Title: Specific oncogenic activity of the Src-family tyrosine kinase c-Yes in colon carcinoma cells.

Journal: PloS one 20110101

Title: EGFR Signaling in Colorectal Carcinoma.

Journal: Pathology research international 20110101

Title: A functional polymorphism in B and T lymphocyte attenuator is associated with susceptibility to rheumatoid arthritis.

Journal: Clinical & developmental immunology 20110101

Title: A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion.

Journal: PloS one 20110101

Title: TACE/ADAM-17 phosphorylation by PKC-epsilon mediates premalignant changes in tobacco smoke-exposed lung cells.

Journal: PloS one 20110101

Title: Diverse requirements for SRC-family tyrosine kinases distinguish chlamydial species.

Journal: mBio 20110101

Title: Oncogene activation induces metabolic transformation resulting in insulin-independence in human breast cancer cells.

Journal: PloS one 20110101

Title: Tyrosine phosphorylation profiling in FGF-2 stimulated human embryonic stem cells.

Journal: PloS one 20110101

Title: A practical guide for the setup of a 1H-31P-13C double cross-polarization (DCP) experiment.

Journal: Solid state nuclear magnetic resonance 20110101

Title: Post-translational modification biology of glutamate receptors and drug addiction.

Journal: Frontiers in neuroanatomy 20110101

Title: Numb protects renal proximal tubular cells from puromycin aminonucleoside-induced apoptosis through inhibiting Notch signaling pathway.

Journal: International journal of biological sciences 20110101

Title: Unexpected long-term protection of adult offspring born to high-fat fed dams against obesity induced by a sucrose-rich diet.

Journal: PloS one 20110101

Title: The alternative splice variant of protein tyrosine kinase 6 negatively regulates growth and enhances PTK6-mediated inhibition of β-catenin.

Journal: PloS one 20110101

Title: Complex interactions between GSK3 and aPKC in Drosophila embryonic epithelial morphogenesis.

Journal: PloS one 20110101

Title: A STAT3-decoy oligonucleotide induces cell death in a human colorectal carcinoma cell line by blocking nuclear transfer of STAT3 and STAT3-bound NF-κB.

Journal: BMC cell biology 20110101

Title: Phylogenetic analysis of kindlins suggests subfunctionalization of an ancestral unduplicated kindlin into three paralogs in vertebrates.

Journal: Evolutionary bioinformatics online 20110101

Title: High-fat diet feeding alters metabolic response to fasting/non fasting conditions. Effect on caveolin expression and insulin signalling.

Journal: Lipids in health and disease 20110101

Title: Cbl enforces Vav1 dependence and a restricted pathway of T cell development.

Journal: PloS one 20110101

Title: Quantitative assays for the measurement of HER1-HER2 heterodimerization and phosphorylation in cell lines and breast tumors: applications for diagnostics and targeted drug mechanism of action.

Journal: Breast cancer research : BCR 20110101

Title: Transcriptional activation of the Axl and PDGFR-α by c-Met through a ras- and Src-independent mechanism in human bladder cancer.

Journal: BMC cancer 20110101

Title: Host plant effects on alkaline phosphatase activity in the whiteflies, Bemisia tabaci Biotype B and Trialeurodes vaporariorum.

Journal: Journal of insect science (Online) 20110101

Title: Proline-rich tyrosine kinase 2 (Pyk2) promotes cell motility of hepatocellular carcinoma through induction of epithelial to mesenchymal transition.

Journal: PloS one 20110101

Title: Vascular endothelial growth factor receptor-2 couples cyclo-oxygenase-2 with pro-angiogenic actions of leptin on human endothelial cells.

Journal: PloS one 20110101

Title: Analysis of Jak2 catalytic function by peptide microarrays: the role of the JH2 domain and V617F mutation.

Journal: PloS one 20110101

Title: Identification of receptor tyrosine kinase, discoidin domain receptor 1 (DDR1), as a potential biomarker for serous ovarian cancer.

Journal: International journal of molecular sciences 20110101

Title: PTB domain-directed substrate targeting in a tyrosine kinase from the unicellular choanoflagellate Monosiga brevicollis.

Journal: PloS one 20110101

Title: Simultaneous siRNA targeting of Src and downstream signaling molecules inhibit tumor formation and metastasis of a human model breast cancer cell line.

Journal: PloS one 20110101

Title: Dual specificity phosphatase 1 regulates human inducible nitric oxide synthase expression by p38 MAP kinase.

Journal: Mediators of inflammation 20110101

Title: Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4.

Journal: BMC biochemistry 20110101

Title: Survey of activated FLT3 signaling in leukemia.

Journal: PloS one 20110101

Title: The structural features of Trask that mediate its anti-adhesive functions.

Journal: PloS one 20110101

Title: Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection.

Journal: Journal of biomedical science 20110101

Title: Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.

Journal: PloS one 20110101

Title: Role of surface chemistry in protein remodeling at the cell-material interface.

Journal: PloS one 20110101

Title: Induction of TLR-2 and TLR-5 expression by Helicobacter pylori switches cagPAI-dependent signalling leading to the secretion of IL-8 and TNF-α.

Journal: PloS one 20110101

Title: A functional nuclear epidermal growth factor receptor, SRC and Stat3 heteromeric complex in pancreatic cancer cells.

Journal: PloS one 20110101

Title: Identification of phosphoproteins as possible differentiation markers in all-trans-retinoic acid-treated neuroblastoma cells.

Journal: PloS one 20110101

Title: Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274.

Journal: Journal of translational medicine 20110101

Title: Insulin resistance in non-obese subjects is associated with activation of the JNK pathway and impaired insulin signaling in skeletal muscle.

Journal: PloS one 20110101

Title: Possible roles of ectophosphatases in host-parasite interactions.

Journal: Journal of parasitology research 20110101

Title: Genistein increases epidermal growth factor receptor signaling and promotes tumor progression in advanced human prostate cancer.

Journal: PloS one 20110101

Title: Mechanism of PhosphoThreonine/Serine Recognition and Specificity for Modular Domains from All-atom Molecular Dynamics.

Journal: BMC biophysics 20110101

Title: Adaptor protein Shc acts as an immune-regulator for the LPS-stimulated maturation of bone marrow-derived dendritic cells.

Journal: BMC immunology 20110101

Title: Ribosomal protein S6 kinase (RSK)-2 as a central effector molecule in RON receptor tyrosine kinase mediated epithelial to mesenchymal transition induced by macrophage-stimulating protein.

Journal: Molecular cancer 20110101

Title: A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample.

Journal: PloS one 20110101

Title: Dynamics of the STAT3 transcription factor: nuclear import dependent on Ran and importin-β1.

Journal: PloS one 20110101

Title: P130Cas attenuates epidermal growth factor (EGF) receptor internalization by modulating EGF-triggered dynamin phosphorylation.

Journal: PloS one 20110101

Title: Deconstructing GSK-3: The Fine Regulation of Its Activity.

Journal: International journal of Alzheimer's disease 20110101

Title: Clinical and technical phosphoproteomic research.

Journal: Proteome science 20110101

Title: Receptor tyrosine kinases in kidney development.

Journal: Journal of signal transduction 20110101

Title: The Dynamical Systems Properties of the HOG Signaling Cascade.

Journal: Journal of signal transduction 20110101

Title: Parasite mitogen-activated protein kinases as drug discovery targets to treat human protozoan pathogens.

Journal: Journal of signal transduction 20110101

Title: Tyrosine Phosphorylation in the C-Terminal Nuclear Localization and Retention Signal (C-NLS) of the EWS Protein.

Journal: Sarcoma 20110101

Title: BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cells.

Journal: PloS one 20110101

Title: PLCβ1-SHP-2 complex, PLCβ1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling?

Journal: Journal of biomedical science 20110101

Title: Antidepressant drugs transactivate TrkB neurotrophin receptors in the adult rodent brain independently of BDNF and monoamine transporter blockade.

Journal: PloS one 20110101

Title: Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer.

Journal: PloS one 20110101

Title: Negative regulation of interferon-β gene expression during acute and persistent virus infections.

Journal: PloS one 20110101

Title: Sunitinib inhibits lymphatic endothelial cell functions and lymph node metastasis in a breast cancer model through inhibition of vascular endothelial growth factor receptor 3.

Journal: Breast cancer research : BCR 20110101

Title: LyGDI, a novel SHIP-interacting protein, is a negative regulator of FcγR-mediated phagocytosis.

Journal: PloS one 20110101

Title: Murine missing in metastasis (MIM) mediates cell polarity and regulates the motility response to growth factors.

Journal: PloS one 20110101

Title: Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages.

Journal: Retrovirology 20110101

Title: Anchored design of protein-protein interfaces.

Journal: PloS one 20110101

Title: PlantPhos: using maximal dependence decomposition to identify plant phosphorylation sites with substrate site specificity.

Journal: BMC bioinformatics 20110101

Title: Analysis of EGFR signaling pathway in nasopharyngeal carcinoma cells by quantitative phosphoproteomics.

Journal: Proteome science 20110101

Title: The complete genome sequence and genetic analysis of ΦCA82 a novel uncultured microphage from the turkey gastrointestinal system.

Journal: Virology journal 20110101

Title: Phosphoproteins regulated by heat stress in rice leaves.

Journal: Proteome science 20110101

Title: Targeting insulin-like growth factor axis in hepatocellular carcinoma.

Journal: Journal of hematology & oncology 20110101

Title: Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism.

Journal: PloS one 20110101

Title: Radioactive phosphorylation of alcohols to monitor biocatalytic Diels-Alder reactions.

Journal: PloS one 20110101

Title: Proteomic analysis of pathways involved in estrogen-induced growth and apoptosis of breast cancer cells.

Journal: PloS one 20110101

Title: Phasic phosphorylation of caldesmon and ERK 1/2 during contractions in human myometrium.

Journal: PloS one 20110101

Title: GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness.

Journal: PloS one 20110101

Title: Amitriptyline-mediated cognitive enhancement in aged 3×Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity.

Journal: PloS one 20110101

Title: Phosphoproteomic profiling of in vivo signaling in liver by the mammalian target of rapamycin complex 1 (mTORC1).

Journal: PloS one 20110101

Title: Overexpression of SIRT1 in mouse forebrain impairs lipid/glucose metabolism and motor function.

Journal: PloS one 20110101

Title: Control of host cell phosphorylation by legionella pneumophila.

Journal: Frontiers in microbiology 20110101

Title: Insulin receptor substrate 2 expression and involvement in neuronal insulin resistance in diabetic neuropathy.

Journal: Experimental diabetes research 20110101

Title: Identification of novel therapeutic targets in microdissected clear cell ovarian cancers.

Journal: PloS one 20110101

Title: Determinants for Substrate Specificity of Protein Phosphatase 2A.

Journal: Enzyme research 20110101

Title: Solution structure of tensin2 SH2 domain and its phosphotyrosine-independent interaction with DLC-1.

Journal: PloS one 20110101

Title: A novel role of protein tyrosine kinase2 in mediating chloride secretion in human airway epithelial cells.

Journal: PloS one 20110101

Title: Association of acid phosphatase locus 1*C allele with the risk of cardiovascular events in rheumatoid arthritis patients.

Journal: Arthritis research & therapy 20110101

Title: Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range.

Journal: Molecular systems biology 20110101

Title: Regulation and function of syk tyrosine kinase in mast cell signaling and beyond.

Journal: Journal of signal transduction 20110101

Title: Functional Diversity of the Schistosoma mansoni Tyrosine Kinases.

Journal: Journal of signal transduction 20110101

Title: Regulation of SRC family kinases in human cancers.

Journal: Journal of signal transduction 20110101

Title: Tyrosine phosphorylation-mediated signaling pathways in dictyostelium.

Journal: Journal of signal transduction 20110101

Title: USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response.

Journal: PloS one 20110101

Title: E7080, a multi-targeted tyrosine kinase inhibitor suppresses tumor cell migration and invasion.

Journal: BMC cancer 20110101

Title: Myricetin Ameliorates Defective Post-Receptor Insulin Signaling via β-Endorphin Signaling in the Skeletal Muscles of Fructose-Fed Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: From the bench to bedside: biological and methodology considerations for the future of companion diagnostics in nonsmall cell lung cancer.

Journal: Pathology research international 20110101

Title: The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology.

Journal: Genome biology 20110101

Title: Administration of chinpi, a component of the herbal medicine ninjin-youei-to, reverses age-induced demyelination.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria.

Journal: PloS one 20110101

Title: The hepatitis E virus ORF3 protein regulates the expression of liver-specific genes by modulating localization of hepatocyte nuclear factor 4.

Journal: PloS one 20110101

Title: A Src-Tks5 pathway is required for neural crest cell migration during embryonic development.

Journal: PloS one 20110101

Title: Protein Tyrosine Phosphatase SHP-2 (PTPN11) in Hematopoiesis and Leukemogenesis.

Journal: Journal of signal transduction 20110101

Title: Tyrosine kinase inhibitor, genistein, reduces renal inflammation and injury in streptozotocin-induced diabetic mice.

Journal: Vascular pharmacology 20110101

Title: The Role of BDNF/TrkB Signaling in Acute Amphetamine-Induced Locomotor Activity and Opioid Peptide Gene Expression in the Rat Dorsal Striatum.

Journal: Frontiers in systems neuroscience 20110101

Title: Intracellular trafficking of the amyloid β-protein precursor (APP) regulated by novel function of X11-like.

Journal: PloS one 20110101

Title: Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway.

Journal: PloS one 20110101

Title: Molecular evolution of the LNX gene family.

Journal: BMC evolutionary biology 20110101

Title: Redox-induced Src kinase and caveolin-1 signaling in TGF-β1-initiated SMAD2/3 activation and PAI-1 expression.

Journal: PloS one 20110101

Title: Quantitative analysis of protein phosphorylations and interactions by multi-colour IP-FCM as an input for kinetic modelling of signalling networks.

Journal: PloS one 20110101

Title: Highly efficient production of soluble proteins from insoluble inclusion bodies by a two-step-denaturing and refolding method.

Journal: PloS one 20110101

Title: Characterization of Leishmania donovani MCM4: expression patterns and interaction with PCNA.

Journal: PloS one 20110101

Title: Simulating EGFR-ERK signaling control by scaffold proteins KSR and MP1 reveals differential ligand-sensitivity co-regulated by Cbl-CIN85 and endophilin.

Journal: PloS one 20110101

Title: Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes.

Journal: Arthritis research & therapy 20110101

Title: Downregulation of TFPI in breast cancer cells induces tyrosine phosphorylation signaling and increases metastatic growth by stimulating cell motility.

Journal: BMC cancer 20110101

Title: Evolutionary versatility of eukaryotic protein domains revealed by their bigram networks.

Journal: BMC evolutionary biology 20110101

Title: PTPBR7 binding proteins in myelinating neurons of the mouse brain.

Journal: International journal of biological sciences 20110101

Title: RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation.

Journal: PloS one 20110101

Title: Evaluating experimental bias and completeness in comparative phosphoproteomics analysis.

Journal: PloS one 20110101

Title: LIP expression is regulated by IGF-1R signaling and participates in suppression of anoikis.

Journal: Molecular cancer 20110101

Title: The Role of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) in Cognition.

Journal: Frontiers in neuroanatomy 20110101

Title: TC-PTP dephosphorylates the guanine nucleotide exchange factor C3G (RapGEF1) and negatively regulates differentiation of human neuroblastoma cells.

Journal: PloS one 20110101

Title: Discovering and validating unknown phospho-sites from p38 and HuR protein kinases in vitro by Phosphoproteomic and Bioinformatic tools.

Journal: Journal of clinical bioinformatics 20110101

Title: HIV-1 Nef induces proinflammatory state in macrophages through its acidic cluster domain: involvement of TNF alpha receptor associated factor 2.

Journal: PloS one 20110101

Title: Spatial association of signaling proteins and F-actin effects on cluster assembly analyzed via photoactivation localization microscopy in T cells.

Journal: PloS one 20110101

Title: Laforin, a dual specificity phosphatase involved in Lafora disease, is present mainly as monomeric form with full phosphatase activity.

Journal: PloS one 20110101

Title: C-KIT signaling depends on microphthalmia-associated transcription factor for effects on cell proliferation.

Journal: PloS one 20110101

Title: Structural and Functional Consequences Induced by Post-Translational Modifications in α-Defensins.

Journal: International journal of peptides 20110101

Title: Protein kinases and phosphatases in the control of cell fate.

Journal: Enzyme research 20110101

Title: SOD3 decreases ischemic injury derived apoptosis through phosphorylation of Erk1/2, Akt, and FoxO3a.

Journal: PloS one 20110101

Title: Phosphoprotein associated with glycosphingolipid-enriched microdomains differentially modulates SRC kinase activity in brain maturation.

Journal: PloS one 20110101

Title: A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death.

Journal: PloS one 20110101

Title: Plasma and cellular fibronectin: distinct and independent functions during tissue repair.

Journal: Fibrogenesis & tissue repair 20110101

Title: FRS2α is essential for the fibroblast growth factor to regulate the mTOR pathway and autophagy in mouse embryonic fibroblasts.

Journal: International journal of biological sciences 20110101

Title: SITC/iSBTc Cancer Immunotherapy Biomarkers Resource Document: online resources and useful tools - a compass in the land of biomarker discovery.

Journal: Journal of translational medicine 20110101

Title: EphA4 blockers promote axonal regeneration and functional recovery following spinal cord injury in mice.

Journal: PloS one 20110101

Title: Modulation of catalytic activity in multi-domain protein tyrosine phosphatases.

Journal: PloS one 20110101

Title: The long noncoding RNA Six3OS acts in trans to regulate retinal development by modulating Six3 activity.

Journal: Neural development 20110101

Title: Abolished adherence alters signaling pathways in phorbol ester-induced human U937 cells.

Journal: Cell communication and signaling : CCS 20110101

Title: erbB3 recruitment of insulin receptor substrate 1 modulates insulin-like growth factor receptor signalling in oestrogen receptor-positive breast cancer cell lines.

Journal: Breast cancer research : BCR 20110101

Title: Decreased expression of dual-specificity phosphatase 9 is associated with poor prognosis in clear cell renal cell carcinoma.

Journal: BMC cancer 20110101

Title: Transcriptome profiling of immune responses to cardiomyopathy syndrome (CMS) in Atlantic salmon.

Journal: BMC genomics 20110101

Title: The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR.

Journal: PloS one 20110101

Title: The functioning of the Drosophila CPEB protein Orb is regulated by phosphorylation and requires casein kinase 2 activity.

Journal: PloS one 20110101

Title: Quantitative phosphoproteomics of CXCL12 (SDF-1) signaling.

Journal: PloS one 20110101

Title: Ankyrin repeat and SOCS box containing protein 4 (Asb-4) colocalizes with insulin receptor substrate 4 (IRS4) in the hypothalamic neurons and mediates IRS4 degradation.

Journal: BMC neuroscience 20110101

Title: Effects of nutritional cues on the duration of the winter anovulatory phase and on associated hormone levels in adult female Welsh pony horses (Equus caballus).

Journal: Reproductive biology and endocrinology : RB&E 20110101

Title: Comparative transcriptome sequencing of germline and somatic tissues of the Ascaris suum gonad.

Journal: BMC genomics 20110101

Title: Targeting HSP90 in ovarian cancers with multiple receptor tyrosine kinase coactivation.

Journal: Molecular cancer 20110101

Title: Profiling the Trypanosoma cruzi phosphoproteome.

Journal: PloS one 20110101

Title: Technical phosphoproteomic and bioinformatic tools useful in cancer research.

Journal: Journal of clinical bioinformatics 20110101

Title: Prenatal cocaine exposure increases synaptic localization of a neuronal RasGEF, GRASP-1 via hyperphosphorylation of AMPAR anchoring protein, GRIP.

Journal: PloS one 20110101

Title: The SOCS2 ubiquitin ligase complex regulates growth hormone receptor levels.

Journal: PloS one 20110101

Title: Nano-stenciled RGD-gold patterns that inhibit focal contact maturation induce lamellipodia formation in fibroblasts.

Journal: PloS one 20110101

Title: Constitutive expression of insulin receptor substrate (IRS)-1 inhibits myogenic differentiation through nuclear exclusion of Foxo1 in L6 myoblasts.

Journal: PloS one 20110101

Title: Nck2 promotes human melanoma cell proliferation, migration and invasion in vitro and primary melanoma-derived tumor growth in vivo.

Journal: BMC cancer 20110101

Title: Gene expression of human lung cancer cell line CL1-5 in response to a direct current electric field.

Journal: PloS one 20110101

Title: Syk protein tyrosine kinase involves PECAM-1 signaling through tandem immunotyrosine inhibitory motifs in human THP-1 macrophages.

Journal: Cellular immunology 20110101

Title: DomPep--a general method for predicting modular domain-mediated protein-protein interactions.

Journal: PloS one 20110101

Title: Modulation of GSK-3 as a Therapeutic Strategy on Tau Pathologies.

Journal: Frontiers in molecular neuroscience 20110101

Title: Structure-activity relationship of halophenols as a new class of protein tyrosine kinase inhibitors.

Journal: International journal of molecular sciences 20110101

Title: Association of reactive oxygen species-mediated signal transduction with in vitro apoptosis sensitivity in chronic lymphocytic leukemia B cells.

Journal: PloS one 20110101

Title: Signal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer.

Journal: Breast cancer research : BCR 20110101

Title: Critical amino acid residues in proteins: a BioMart integration of Reactome protein annotations with PRIDE mass spectrometry data and COSMIC somatic mutations.

Journal: Database : the journal of biological databases and curation 20110101

Title: The role of atypical protein kinase C in CSF-1-dependent Erk activation and proliferation in myeloid progenitors and macrophages.

Journal: PloS one 20110101

Title: The adaptor protein SH2B3 (Lnk) negatively regulates neurite outgrowth of PC12 cells and cortical neurons.

Journal: PloS one 20110101

Title: β-Adrenergic receptor-PI3K signaling crosstalk in mouse heart: elucidation of immediate downstream signaling cascades.

Journal: PloS one 20110101

Title: Hypoxic pulmonary hypertension in mice with constitutively active platelet-derived growth factor receptor-β.

Journal: Pulmonary circulation 20110101

Title: Inferring pleiotropy by network analysis: linked diseases in the human PPI network.

Journal: BMC systems biology 20110101

Title: The secret life of kinases: functions beyond catalysis.

Journal: Cell communication and signaling : CCS 20110101

Title: The synthetic tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis.

Journal: Critical care (London, England) 20110101

Title: BID-F1 and BID-F2 domains of Bartonella henselae effector protein BepF trigger together with BepC the formation of invasome structures.

Journal: PloS one 20110101

Title: Mechanism of acetylcholine receptor cluster formation induced by DC electric field.

Journal: PloS one 20110101

Title: Methanosarcina acetivorans C2A topoisomerase IIIα, an archaeal enzyme with promiscuity in divalent cation dependence.

Journal: PloS one 20110101

Title: Palmitate-activated macrophages confer insulin resistance to muscle cells by a mechanism involving protein kinase C θ and ε.

Journal: PloS one 20110101

Title: Erythropoietin enhances nerve repair in anti-ganglioside antibody-mediated models of immune neuropathy.

Journal: PloS one 20110101

Title: Crystal structure of thrombin in complex with S-variegin: insights of a novel mechanism of inhibition and design of tunable thrombin inhibitors.

Journal: PloS one 20110101

Title: Molecular markers to characterize the hermaphroditic reproductive system of the planarian Schmidtea mediterranea.

Journal: BMC developmental biology 20110101

Title: ALK and NSCLC: Targeted therapy with ALK inhibitors.

Journal: F1000 medicine reports 20110101

Title: Role and expression of FRS2 and FRS3 in prostate cancer.

Journal: BMC cancer 20110101

Title: Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility.

Journal: BMC cell biology 20110101

Title: Biochemical and computational analysis of LNX1 interacting proteins.

Journal: PloS one 20110101

Title: DNA damage stress and inhibition of Jak2-V617F cause its degradation and synergistically induce apoptosis through activation of GSK3β.

Journal: PloS one 20110101

Title: Evasion of Host Defence by Leishmania donovani: Subversion of Signaling Pathways.

Journal: Molecular biology international 20110101

Title: Use of antimony in the treatment of leishmaniasis: current status and future directions.

Journal: Molecular biology international 20110101

Title: Activation of neutrophils by nanoparticles.

Journal: TheScientificWorldJournal 20110101

Title: Suppressor of cytokine signalling-6 promotes neurite outgrowth via JAK2/STAT5-mediated signalling pathway, involving negative feedback inhibition.

Journal: PloS one 20110101

Title: Bidirectional remodeling of β1-integrin adhesions during chemotropic regulation of nerve growth.

Journal: BMC biology 20110101

Title: Insulin receptor-mediated signaling via phospholipase C-γ regulates growth and differentiation in Drosophila.

Journal: PloS one 20110101

Title: Mutations in the catalytic loop HRD motif alter the activity and function of Drosophila Src64.

Journal: PloS one 20110101

Title: Regulation of suppressors of cytokine signaling as a therapeutic approach in autoimmune diseases, with an emphasis on multiple sclerosis.

Journal: Journal of signal transduction 20110101

Title: Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II.

Journal: PloS one 20110101

Title: Stat3 mediates expression of autotaxin in breast cancer.

Journal: PloS one 20110101

Title: Spectrum of oncogenic driver mutations in lung adenocarcinomas from East Asian never smokers.

Journal: PloS one 20110101

Title: MUC1-C oncoprotein regulates glycolysis and pyruvate kinase M2 activity in cancer cells.

Journal: PloS one 20110101

Title: Regulation of hTERT by BCR-ABL at multiple levels in K562 cells.

Journal: BMC cancer 20110101

Title: The SH2 domain-containing proteins in 21 species establish the provenance and scope of phosphotyrosine signaling in eukaryotes.

Journal: Science signaling 20110101

Title: Crizotinib: a novel and first-in-class multitargeted tyrosine kinase inhibitor for the treatment of anaplastic lymphoma kinase rearranged non-small cell lung cancer and beyond.

Journal: Drug design, development and therapy 20110101

Title: Disabled-1 alternative splicing in human fetal retina and neural tumors.

Journal: PloS one 20110101

Title: Tyrosine phosphorylation of Rac1: a role in regulation of cell spreading.

Journal: PloS one 20110101

Title: Inhibition of interferon induction and action by the nairovirus Nairobi sheep disease virus/Ganjam virus.

Journal: PloS one 20110101

Title: The tyrosine kinase inhibitor dasatinib induces a marked adipogenic differentiation of human multipotent mesenchymal stromal cells.

Journal: PloS one 20110101

Title: Development of derivatives of 3, 3'-diindolylmethane as potent Leishmania donovani bi-subunit topoisomerase IB poisons.

Journal: PloS one 20110101

Title: Phosphorylation of Akt and ERK1/2 is required for VEGF-A/VEGFR2-induced proliferation and migration of lymphatic endothelium.

Journal: PloS one 20110101

Title: Continuous requirement of ErbB2 kinase activity for loss of cell polarity and lumen formation in a novel ErbB2/Neu-driven murine cell line model of metastatic breast cancer.

Journal: Journal of carcinogenesis 20110101

Title: PEGylation potentiates the effectiveness of an antagonistic peptide that targets the EphB4 receptor with nanomolar affinity.

Journal: PloS one 20110101

Title: Nephrin regulates lamellipodia formation by assembling a protein complex that includes Ship2, filamin and lamellipodin.

Journal: PloS one 20110101

Title: Systems biology modeling reveals a possible mechanism of the tumor cell death upon oncogene inactivation in EGFR addicted cancers.

Journal: PloS one 20110101

Title: Cyclic stress at mHz frequencies aligns fibroblasts in direction of zero strain.

Journal: PloS one 20110101

Title: Curative effect of 18β-glycyrrhetinic acid in experimental visceral leishmaniasis depends on phosphatase-dependent modulation of cellular MAP kinases.

Journal: PloS one 20110101

Title: Polarized endocytosis of the keratinocyte growth factor receptor in migrating cells: role of SRC-signaling and cortactin.

Journal: PloS one 20110101

Title: Fish Suppressors of Cytokine Signaling (SOCS): Gene Discovery, Modulation of Expression and Function.

Journal: Journal of signal transduction 20110101

Title: Tyrosine kinase chromosomal translocations mediate distinct and overlapping gene regulation events.

Journal: BMC cancer 20110101

Title: Mechanism and regulation of nucleocytoplasmic trafficking of smad.

Journal: Cell & bioscience 20110101

Title: A cell-based protein-protein interaction method using a permuted luciferase reporter.

Journal: Current chemical genomics 20110101

Title: A crucial role of activin A-mediated growth hormone suppression in mouse and human heart failure.

Journal: PloS one 20110101

Title: Deep-sequencing analysis of the mouse transcriptome response to infection with Brucella melitensis strains of differing virulence.

Journal: PloS one 20110101

Title: Lapatinib induces autophagy, apoptosis and megakaryocytic differentiation in chronic myelogenous leukemia K562 cells.

Journal: PloS one 20110101

Title: Role of palladin phosphorylation by extracellular signal-regulated kinase in cell migration.

Journal: PloS one 20110101

Title: Novel insights into the role of caveolin-2 in cell- and tissue-specific signaling and function.

Journal: Biochemistry research international 20110101

Title: The Shc family protein adaptor, Rai, negatively regulates T cell antigen receptor signaling by inhibiting ZAP-70 recruitment and activation.

Journal: PloS one 20110101

Title: Fast disintegrating tablets: Opportunity in drug delivery system.

Journal: Journal of advanced pharmaceutical technology & research 20110101

Title: Advances in carcinogenic metal toxicity and potential molecular markers.

Journal: International journal of molecular sciences 20110101

Title: Phosphoproteomics-based systems analysis of signal transduction networks.

Journal: Frontiers in physiology 20110101

Title: Tuning the orchestra: transcriptional pathways controlling axon regeneration.

Journal: Frontiers in molecular neuroscience 20110101

Title: Signal protein-derived peptides as functional probes and regulators of intracellular signaling.

Journal: Journal of amino acids 20110101

Title: Mechanisms of brain aging regulation by insulin: implications for neurodegeneration in late-onset Alzheimer's disease.

Journal: ISRN neurology 20110101

Title: Initiation of TCR phosphorylation and signal transduction.

Journal: Frontiers in immunology 20110101

Title: Adiponectin action: a combination of endocrine and autocrine/paracrine effects.

Journal: Frontiers in endocrinology 20110101

Title: Landmarks in insulin research.

Journal: Frontiers in endocrinology 20110101

Title: The insulin receptor: a new target for cancer therapy.

Journal: Frontiers in endocrinology 20110101

Title: PI3K Pathway in NSCLC.

Journal: Frontiers in oncology 20110101

Title: Allosteric regulation of glycogen synthase kinase 3β: a theoretical study.

Journal: Biochemistry 20101228

Title: A protected l-bromophosphonomethylphenylalanine amino acid derivative (BrPmp) for synthesis of irreversible protein tyrosine phosphatase inhibitors.

Journal: Bioorganic & medicinal chemistry 20101215

Title: CEACAM1: a key regulator of vascular permeability.

Journal: Journal of cell science 20101215

Title: Silencing of the PP2A catalytic subunit causes HER-2/neu positive breast cancer cells to undergo apoptosis.

Journal: Experimental cell research 20101210

Title: Is there an association with phosphorylation and dephosphorylation of Src kinase at tyrosine 530 and breast cancer patient disease-specific survival.

Journal: British journal of cancer 20101207

Title: Identification of tyrosine phosphoproteins in signaling pathway triggered TGF-a by using functional proteomics technology.

Journal: Medical oncology (Northwood, London, England) 20101201

Title: Phosphate ester hydrolysis of biologically relevant molecules by cerium oxide nanoparticles.

Journal: Nanomedicine : nanotechnology, biology, and medicine 20101201

Title: Comprehensive analysis of phosphorylation sites in Tensin1 reveals regulation by p38MAPK.

Journal: Molecular & cellular proteomics : MCP 20101201

Title: Pseudokinases-remnants of evolution or key allosteric regulators?

Journal: Current opinion in structural biology 20101201

Title: AZ960, a novel Jak2 inhibitor, induces growth arrest and apoptosis in adult T-cell leukemia cells.

Journal: Molecular cancer therapeutics 20101201

Title: Interaction of c-Cbl with myosin IIA regulates Bleb associated macropinocytosis of Kaposi's sarcoma-associated herpesvirus.

Journal: PLoS pathogens 20101201

Title: Modulation of protein tyrosine phosphorylation in gastric mucosa during re-epithelization processes.

Journal: World journal of biological chemistry 20101126

Title: Rate enhancement of an interfacial biochemical reaction through localization of substrate and enzyme by an adaptor domain.

Journal: The journal of physical chemistry. B 20101125

Title: The streptococcal collagen-binding protein CNE specifically interferes with alphaVbeta3-mediated cellular interactions with triple helical collagen.

Journal: The Journal of biological chemistry 20101112

Title: Integrin {beta}3 phosphorylation dictates its complex with the Shc phosphotyrosine-binding (PTB) domain.

Journal: The Journal of biological chemistry 20101105

Title: Expression of oncogenic K-ras and loss of Smad4 cooperate to induce the expression of EGFR and to promote invasion of immortalized human pancreas ductal cells.

Journal: International journal of cancer 20101101

Title: Protein kinase substrate profiling with a high-density peptide microarray.

Journal: Combinatorial chemistry & high throughput screening 20101101

Title: SH2 domains recognize contextual peptide sequence information to determine selectivity.

Journal: Molecular & cellular proteomics : MCP 20101101

Title: EphA3 functions are regulated by collaborating phosphotyrosine residues.

Journal: Cell research 20101101

Title: A cell-based screen for inhibitors of protein folding and degradation.

Journal: Cell stress & chaperones 20101101

Title: Platelet endothelial cell adhesion molecule-1 regulates collagen-stimulated platelet function by modulating the association of phosphatidylinositol 3-kinase with Grb-2-associated binding protein-1 and linker for activation of T cells.

Journal: Journal of thrombosis and haemostasis : JTH 20101101

Title: Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia.

Journal: Journal of cell science 20101101

Title: The Caenorhabditis elegans Kinesin-3 motor UNC-104/KIF1A is degraded upon loss of specific binding to cargo.

Journal: PLoS genetics 20101101

Title: Tyrosine phosphorylation enrichment and subsequent analysis by MALDI-TOF/TOF MS/MS and LC-ESI-IT-MS/MS.

Journal: Current protocols in protein science 20101101

Title: Fcγ receptor I alpha chain (CD64) expression in macrophages is critical for the onset of meningitis by Escherichia coli K1.

Journal: PLoS pathogens 20101101

Title: A computational approach to analyze the mechanism of action of the kinase inhibitor bafetinib.

Journal: PLoS computational biology 20101101

Title: Functional phosphoproteomic analysis reveals cold-shock domain protein A to be a Bcr-Abl effector-regulating proliferation and transformation in chronic myeloid leukemia.

Journal: Cell death & disease 20101101

Title: Clinical, Molecular, and Genetic Characteristics of PAPA Syndrome: A Review.

Journal: Current genomics 20101101

Title: Lipid rafts and redox regulation of cellular signaling in cholesterol induced atherosclerosis.

Journal: Current cardiology reviews 20101101

Title: Detection of tyrosine phosphorylated proteins by combination of immunoaffinity enrichment, two-dimensional difference gel electrophoresis and fluorescent Western blotting.

Journal: Biochemical and biophysical research communications 20101029

Title: Mycobacterium tuberculosis tyrosine phosphatase A (PtpA) activity is modulated by S-nitrosylation.

Journal: Chemical communications (Cambridge, England) 20101028

Title: Early response to ErbB2 over-expression in polarized Caco-2 cells involves partial segregation from ErbB3 by relocalization to the apical surface and initiation of survival signaling.

Journal: Journal of cellular biochemistry 20101015

Title: The Structure of the talin head reveals a novel extended conformation of the FERM domain.

Journal: Structure (London, England : 1993) 20101013

Title: Evaluation of erythrocyte band 3 phosphotyrosine level, glutathione content, CA-125, and human epididymal secretory protein E4 as combined parameters in endometriosis.

Journal: Fertility and sterility 20101001

Title: Trypanosomatid protein phosphatases.

Journal: Molecular and biochemical parasitology 20101001

Title: Infrequent methylation of the DUSP6 phosphatase in endometrial cancer.

Journal: Gynecologic oncology 20101001

Title: Disabled-2 is required for mesoderm differentiation of murine embryonic stem cells.

Journal: Journal of cellular physiology 20101001

Title: CLE14/CLE20 peptides may interact with CLAVATA2/CORYNE receptor-like kinases to irreversibly inhibit cell division in the root meristem of Arabidopsis.

Journal: Planta 20101001

Title: Wnt5a/Ror2-induced upregulation of xPAPC requires xShcA.

Journal: Biochemical and biophysical research communications 20101001

Title: Analysis of changes in tyrosine and serine phosphorylation of red cell membrane proteins induced by P. falciparum growth.

Journal: Proteomics 20101001

Title: A dynamic immunological synapse mediates homeostatic TCR-dependent and -independent signaling.

Journal: European journal of immunology 20101001

Title: Integrated data management and validation platform for phosphorylated tandem mass spectrometry data.

Journal: Proteomics 20101001

Title: Binding of flexible and constrained ligands to the Grb2 SH2 domain: structural effects of ligand preorganization.

Journal: Acta crystallographica. Section D, Biological crystallography 20101001

Title: Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63.

Journal: PLoS pathogens 20101001

Title: Genotoxicity and cytotoxicity of zinc oxide and titanium dioxide in HEp-2 cells.

Journal: Nanomedicine (London, England) 20101001

Title: Phosphotyrosine signaling: evolving a new cellular communication system.

Journal: Cell 20100903

Title: DUSP26 negatively affects the proliferation of epithelial cells, an effect not mediated by dephosphorylation of MAPKs.

Journal: Biochimica et biophysica acta 20100901

Title: The human megakaryocytic cell line UT-7/TPO expresses functional platelet agonist signals mediated through GPVI and thromboxane receptor.

Journal: Cell biology international 20100901

Title: The structure of invadopodia in a complex 3D environment.

Journal: European journal of cell biology 20100901

Title: Elimination of negative feedback control mechanisms along the insulin signaling pathway improves beta-cell function under stress.

Journal: Diabetes 20100901

Title: Role of glycerol-3-phosphate dehydrogenase 2 in mouse sperm capacitation.

Journal: Molecular reproduction and development 20100901

Title: Somatostatin receptor activation (sst(1) -sst(5) ) differentially influences human retinal pigment epithelium cell viability.

Journal: Acta ophthalmologica 20100901

Title: Prophossi: automating expert validation of phosphopeptide-spectrum matches from tandem mass spectrometry.

Journal: Bioinformatics (Oxford, England) 20100901

Title: Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development.

Journal: Genesis (New York, N.Y. : 2000) 20100901

Title: Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20100901

Title: Lineage-specific expansion of DNA-binding transcription factor families.

Journal: Trends in genetics : TIG 20100901

Title: The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis.

Journal: Angiogenesis 20100901

Title: Constraining binding hot spots: NMR and molecular dynamics simulations provide a structural explanation for enthalpy-entropy compensation in SH2-ligand binding.

Journal: Journal of the American Chemical Society 20100818

Title: Mechanism of tyrosine phosphorylation of procaspase-9 and Apaf-1 in cytosolic fractions of the cerebral cortex of newborn piglets during hypoxia.

Journal: Neuroscience letters 20100809

Title: Identification of phosphorylation-dependent interaction partners of the adapter protein ADAP using quantitative mass spectrometry: SILAC vs (18)O-labeling.

Journal: Journal of proteome research 20100806

Title: An X11alpha/FSBP complex represses transcription of the GSK3beta gene promoter.

Journal: Neuroreport 20100804

Title: Syndecan- and integrin-binding peptides synergistically accelerate cell adhesion.

Journal: FEBS letters 20100804

Title: Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.

Journal: FEBS letters 20100804

Title: Involvement of receptor tyrosine phosphatase DEP-1 mediated PI3K-cofilin signaling pathway in sorafenib-induced cytoskeletal rearrangement in hepatoma cells.

Journal: Journal of cellular physiology 20100801

Title: Multiplex analysis of Src family kinase signaling by microbead suspension arrays.

Journal: Assay and drug development technologies 20100801

Title: Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women.

Journal: Diabetes 20100801

Title: Syntheses and activities of backbone-side chain cyclic octapeptide ligands with N-functionalized phosphotyrosine for the N-terminal SH2-domain of the protein tyrosine phosphatase SHP-1.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20100801

Title: Sorafenib activates CD95 and promotes autophagy and cell death via Src family kinases in gastrointestinal tumor cells.

Journal: Molecular cancer therapeutics 20100801

Title: Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements.

Journal: PLoS biology 20100801

Title: IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition.

Journal: PLoS biology 20100801

Title: Investigation of mechanism of p38 MAPK activation in renal epithelial cell from distal tubules triggered by cardiotonic steroids.

Journal: Biochemistry. Biokhimiia 20100801

Title: Estrogen receptor alpha phosphorylated at tyrosine 537 is associated with poor clinical outcome in breast cancer patients treated with tamoxifen.

Journal: Hormones & cancer 20100801

Title: PTP1B targets the endosomal sorting machinery: dephosphorylation of regulatory sites on the endosomal sorting complex required for transport component STAM2.

Journal: The Journal of biological chemistry 20100730

Title: Two novel Src homology 2 domain proteins interact to regulate dictyostelium gene expression during growth and early development.

Journal: The Journal of biological chemistry 20100723

Title: A small fibronectin-mimicking protein from bacteria induces cell spreading and focal adhesion formation.

Journal: The Journal of biological chemistry 20100723

Title: The Trypanosoma brucei life cycle switch TbPTP1 is structurally conserved and dephosphorylates the nucleolar protein NOPP44/46.

Journal: The Journal of biological chemistry 20100716

Title: Ectodomain shedding of interleukin-2 receptor beta and generation of an intracellular functional fragment.

Journal: The Journal of biological chemistry 20100716

Title: Vascular endothelial growth factors and vascular permeability.

Journal: Cardiovascular research 20100715

Title: Laforin, the most common protein mutated in Lafora disease, regulates autophagy.

Journal: Human molecular genetics 20100715

Title: Increased circulating cell signalling phosphoproteins in sera are useful for the detection of pancreatic cancer.

Journal: British journal of cancer 20100713

Title: Neuromedin B receptors regulate EGF receptor tyrosine phosphorylation in lung cancer cells.

Journal: European journal of pharmacology 20100710

Title: The cytoplasmic adaptor protein Dok7 activates the receptor tyrosine kinase MuSK via dimerization.

Journal: Molecular cell 20100709

Title: Development of a two-part strategy to identify a therapeutic human bispecific antibody that inhibits IgE receptor signaling.

Journal: The Journal of biological chemistry 20100702

Title: Synthetic strategies to a backbone-side chain cyclic SHP-1 N-SH2 ligand containing N-functionalized alkyl phosphotyrosine.

Journal: Protein and peptide letters 20100701

Title: Elucidation of the signaling pathways that underpin capacitation-associated surface phosphotyrosine expression in mouse spermatozoa.

Journal: Journal of cellular physiology 20100701

Title: Polychlorinated biphenyls disrupt intestinal integrity via NADPH oxidase-induced alterations of tight junction protein expression.

Journal: Environmental health perspectives 20100701

Title: Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009.

Journal: Diabetologia 20100701

Title: Proteomics study of oxidative stress and Src kinase inhibition in H9C2 cardiomyocytes: a cell model of heart ischemia-reperfusion injury and treatment.

Journal: Free radical biology & medicine 20100701

Title: EZYprep LC-coupled MALDI-TOF/TOF MS: an improved matrix spray application for phosphopeptide characterisation.

Journal: Proteomics 20100701

Title: NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH.

Journal: Chemical biology & drug design 20100701

Title: Phosphotyrosine signaling analysis of site-specific mutations on EGFRvIII identifies determinants governing glioblastoma cell growth.

Journal: Molecular bioSystems 20100701

Title: Thermodynamics of phosphotyrosine peptide-peptoid hybrids binding to the p56lck SH2 domain.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20100701

Title: Plasmodium falciparum adhesion on human brain microvascular endothelial cells involves transmigration-like cup formation and induces opening of intercellular junctions.

Journal: PLoS pathogens 20100701

Title: Protein kinase C activation has distinct effects on the localization, phosphorylation and detergent solubility of the claudin protein family in tight and leaky epithelial cells.

Journal: The Journal of membrane biology 20100701

Title: Src activates Abl to augment Robo1 expression in order to promote tumor cell migration.

Journal: Oncotarget 20100701

Title: PEAK1, a novel kinase target in the fight against cancer.

Journal: Oncotarget 20100701

Title: Phosphorylation of Puma modulates its apoptotic function by regulating protein stability.

Journal: Cell death & disease 20100701

Title: Uncoupling of T cell receptor zeta chain function during the induction of anergy by the superantigen, staphylococcal enterotoxin A.

Journal: Toxins 20100701

Title: Mutations in MUSK causing congenital myasthenic syndrome impair MuSK-Dok-7 interaction.

Journal: Human molecular genetics 20100615

Title: T-cell receptor early signalling complex activation in response to interferon-alpha receptor stimulation.

Journal: The Biochemical journal 20100615

Title: Probing protein kinase (CK2) and alkaline phosphatase with CdSe/ZnS quantum dots.

Journal: Nano letters 20100609

Title: Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology.

Journal: Journal of proteome research 20100604

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling in diabetes prone and resistant mice.

Journal: Journal of proteome research 20100604

Title: Genomic Analysis Highlights the Role of the JAK-STAT Signaling in the Anti-proliferative Effects of Dietary Flavonoid-'Ashwagandha' in Prostate Cancer Cells.

Journal: Evidence-based complementary and alternative medicine : eCAM 20100601

Title: I-BAR domains, IRSp53 and filopodium formation.

Journal: Seminars in cell & developmental biology 20100601

Title: Glomerular proteins related to slit diaphragm and matrix adhesion in the foot processes are highly tyrosine phosphorylated in the normal rat kidney.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100601

Title: Phosphorylation of thymidylate synthase from various sources by human protein kinase CK2 and its catalytic subunits.

Journal: Bioorganic chemistry 20100601

Title: Trafficking defects and loss of ligand binding are the underlying causes of all reported DDR2 missense mutations found in SMED-SL patients.

Journal: Human molecular genetics 20100601

Title: TBC1D1 regulates insulin- and contraction-induced glucose transport in mouse skeletal muscle.

Journal: Diabetes 20100601

Title: Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue.

Journal: Diabetes 20100601

Title: Proteins from human oviductal tissue-conditioned medium modulate sperm capacitation.

Journal: Human reproduction (Oxford, England) 20100601

Title: A novel bile acid-activated vitamin D receptor signaling in human hepatocytes.

Journal: Molecular endocrinology (Baltimore, Md.) 20100601

Title: Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2.

Journal: Journal of structural and functional genomics 20100601

Title: Cytoskeleton-modulating effectors of enteropathogenic and enterohaemorrhagic Escherichia coli: Tir, EspFU and actin pedestal assembly.

Journal: The FEBS journal 20100601

Title: RBC membrane damage and decreased band 3 phospho-tyrosine phosphatase activity are markers of COPD progression.

Journal: Frontiers in bioscience (Elite edition) 20100601

Title: Molecular mechanism of insulin resistance in obesity and type 2 diabetes.

Journal: The Korean journal of internal medicine 20100601

Title: Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis.

Journal: The FEBS journal 20100601

Title: Whole-genome sequencing of a single proband together with linkage analysis identifies a Mendelian disease gene.

Journal: PLoS genetics 20100601

Title: Plato's cave algorithm: inferring functional signaling networks from early gene expression shadows.

Journal: PLoS computational biology 20100601

Title: A novel small-molecule disrupts Stat3 SH2 domain-phosphotyrosine interactions and Stat3-dependent tumor processes.

Journal: Biochemical pharmacology 20100515

Title: The heterohexameric complex structure, a component in the non-classical pathway for fibroblast growth factor 1 (FGF1) secretion.

Journal: The Journal of biological chemistry 20100514

Title: Insulin-like growth factor-binding protein 7 alters the sensitivity to interferon-based anticancer therapy in hepatocellular carcinoma cells.

Journal: British journal of cancer 20100511

Title: c-Abl, Lamellipodin, and Ena/VASP proteins cooperate in dorsal ruffling of fibroblasts and axonal morphogenesis.

Journal: Current biology : CB 20100511

Title: Heparan sulfate chain valency controls syndecan-4 function in cell adhesion.

Journal: The Journal of biological chemistry 20100507

Title: Quantitative analysis of HGF and EGF-dependent phosphotyrosine signaling networks.

Journal: Journal of proteome research 20100507

Title: Differential phosphoproteomics of fibroblast growth factor signaling: identification of Src family kinase-mediated phosphorylation events.

Journal: Journal of proteome research 20100507

Title: An unnatural amino acid that mimics phosphotyrosine.

Journal: Chemical communications (Cambridge, England) 20100507

Title: Analysis of novel phospho-ITAM specific antibodies in a S2 reconstitution system for TCR-CD3 signalling.

Journal: Immunology letters 20100504

Title: Loops govern SH2 domain specificity by controlling access to binding pockets.

Journal: Science signaling 20100504

Title: A robust error model for iTRAQ quantification reveals divergent signaling between oncogenic FLT3 mutants in acute myeloid leukemia.

Journal: Molecular & cellular proteomics : MCP 20100501

Title: High glucose induces suppression of insulin signalling and apoptosis via upregulation of endogenous IL-1beta and suppressor of cytokine signalling-1 in mouse pancreatic beta cells.

Journal: Cellular signalling 20100501

Title: The Bcr-Abl kinase regulates the actin cytoskeleton via a GADS/Slp-76/Nck1 adaptor protein pathway.

Journal: Cellular signalling 20100501

Title: Protein tyrosine phosphatase SHP-1 positively regulates TLR-induced IL-12p40 production in macrophages through inhibition of phosphatidylinositol 3-kinase.

Journal: Journal of leukocyte biology 20100501

Title: The pseudophosphatase MK-STYX interacts with G3BP and decreases stress granule formation.

Journal: The Biochemical journal 20100501

Title: Regulation of hyperactivation by PPP2 in hamster spermatozoa.

Journal: Reproduction (Cambridge, England) 20100501

Title: Tyrosine phosphorylation of SHIP promotes its proteasomal degradation.

Journal: Experimental hematology 20100501

Title: Inhibition of c-Met with the specific small molecule tyrosine kinase inhibitor SU11274 decreases growth and metastasis formation of experimental human melanoma.

Journal: Current cancer drug targets 20100501

Title: New Cdc2 Tyr 4 phosphorylation by dsRNA-activated protein kinase triggers Cdc2 polyubiquitination and G2 arrest under genotoxic stresses.

Journal: EMBO reports 20100501

Title: Asymmetric tyrosine kinase arrangements in activation or autophosphorylation of receptor tyrosine kinases.

Journal: Molecules and cells 20100501

Title: Leishmania donovani isolates with antimony-resistant but not -sensitive phenotype inhibit sodium antimony gluconate-induced dendritic cell activation.

Journal: PLoS pathogens 20100501

Title: Protein kinase Cθ is required for cardiomyocyte survival and cardiac remodeling.

Journal: Cell death & disease 20100501

Title: VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts.

Journal: The EMBO journal 20100421

Title: Deoxygenation affects tyrosine phosphoproteome of red cell membrane from patients with sickle cell disease.

Journal: Blood cells, molecules & diseases 20100415

Title: Regulation of vascular endothelial function by procyanidin-rich foods and beverages.

Journal: Journal of agricultural and food chemistry 20100414

Title: Novel monoclonal antibodies recognizing the active conformation of epidermal growth factor receptor.

Journal: Biochemical and biophysical research communications 20100409

Title: Insulin receptor substrate-3, interacting with Bcl-3, enhances p50 NF-kappaB activity.

Journal: Biochemical and biophysical research communications 20100409

Title: The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion.

Journal: The Journal of biological chemistry 20100402

Title: Effects of micrometric titanium particles on osteoblast attachment and cytoskeleton architecture.

Journal: Acta biomaterialia 20100401

Title: Increased CYP2J3 expression reduces insulin resistance in fructose-treated rats and db/db mice.

Journal: Diabetes 20100401

Title: FcepsilonRI beta-chain ITAM amplifies PI3K-signaling to ensure synergistic degranulation response via FcepsilonRI and adenosine receptors.

Journal: European journal of immunology 20100401

Title: Differential phosphorylation of functional tyrosines in CD19 modulates B-lymphocyte activation.

Journal: European journal of immunology 20100401

Title: Impact of rs361072 in the phosphoinositide 3-kinase p110beta gene on whole-body glucose metabolism and subunit protein expression in skeletal muscle.

Journal: Diabetes 20100401

Title: Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance.

Journal: Journal of biochemistry 20100401

Title: Screening kinase inhibitors with a microarray-based fluorescent and resonance light scattering assay.

Journal: Analytical chemistry 20100401

Title: Anergic CD4+ T cells form mature immunological synapses with enhanced accumulation of c-Cbl and Cbl-b.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20100401

Title: A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain.

Journal: Nature structural & molecular biology 20100401

Title: Metabolic network topology reveals transcriptional regulatory signatures of type 2 diabetes.

Journal: PLoS computational biology 20100401

Title: Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3.

Journal: Molecular cancer therapeutics 20100401

Title: [New functional proteins identified by proteomic analysis in the epidermal growth factor receptor-mediated signaling pathway and application for practical use].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20100401

Title: Detecting tyrosine-phosphorylated proteins by Western blot analysis.

Journal: Current protocols in immunology 20100401

Title: Role of the osmotic stress regulatory pathway in morphogenesis and secondary metabolism in filamentous fungi.

Journal: Toxins 20100401

Title: A double point mutation in PCL-gamma1 (Y509A/F510A) enhances Y783 phosphorylation and inositol phospholipid-hydrolyzing activity upon EGF stimulation.

Journal: Experimental & molecular medicine 20100331

Title: NOS1AP associates with Scribble and regulates dendritic spine development.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100331

Title: Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survival.

Journal: The Journal of biological chemistry 20100326

Title: Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm.

Journal: The Journal of biological chemistry 20100326

Title: CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development.

Journal: Immunity 20100326

Title: Quantitative reconstitution of mitotic CDK1 activation in somatic cell extracts.

Journal: Molecular cell 20100326

Title: Functional interaction of the Ras effector RASSF5 with the tyrosine kinase Lck: critical role in nucleocytoplasmic transport and cell cycle regulation.

Journal: Journal of molecular biology 20100319

Title: Regulation of actin polymerization and adhesion-dependent cell edge protrusion by the Abl-related gene (Arg) tyrosine kinase and N-WASp.

Journal: Biochemistry 20100316

Title: A new Dictyostelium prestalk cell sub-type.

Journal: Developmental biology 20100315

Title: Insufficient deactivation of the protein tyrosine kinase lck amplifies T-cell responsiveness in acute coronary syndrome.

Journal: Circulation research 20100305

Title: p66shc inhibits insulin-like growth factor-I signaling via direct binding to Src through its polyproline and Src homology 2 domains, resulting in impairment of Src kinase activation.

Journal: The Journal of biological chemistry 20100305

Title: The PTB domain of ShcA couples receptor activation to the cytoskeletal regulator IQGAP1.

Journal: The EMBO journal 20100303

Title: AMP N(1)-oxide, a unique compound of royal jelly, induces neurite outgrowth from PC12 cells via signaling by protein kinase A independent of that by mitogen-activated protein kinase.

Journal: Evidence-based complementary and alternative medicine : eCAM 20100301

Title: Fabrication and characterization of a recombinant fibronectin/cadherin bio-inspired ceramic surface and its influence on adhesion and ossification in vitro.

Journal: Acta biomaterialia 20100301

Title: Orexins/hypocretins and orexin receptors in apoptosis: a mini-review.

Journal: Acta physiologica (Oxford, England) 20100301

Title: Regulation of tyrosine kinase activity during capacitation in goat sperm.

Journal: Molecular and cellular biochemistry 20100301

Title: Human IL6 enhances leptin action in mice.

Journal: Diabetologia 20100301

Title: Effects of angiopoietins-1 and -2 on the receptor tyrosine kinase Tie2 are differentially regulated at the endothelial cell surface.

Journal: Cellular signalling 20100301

Title: IGF-1 receptors in Xenopus laevis ovarian follicle cells support the oocyte maturation response.

Journal: Biology of reproduction 20100301

Title: Cell membrane extensions, generated by mechanical constraint, are associated with a sustained lipid raft patching and an increased cell signaling.

Journal: Biochimica et biophysica acta 20100301

Title: Role of protein tyrosine phosphatase SHP2 in barrier function of pulmonary endothelium.

Journal: American journal of physiology. Lung cellular and molecular physiology 20100301

Title: Prolactin exerts a prosurvival effect on human spermatozoa via mechanisms that involve the stimulation of Akt phosphorylation and suppression of caspase activation and capacitation.

Journal: Endocrinology 20100301

Title: Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation.

Journal: Journal of thrombosis and haemostasis : JTH 20100301

Title: Global phosphoproteomic effects of natural tyrosine kinase inhibitor, genistein, on signaling pathways.

Journal: Proteomics 20100301

Title: Prepubertal genistein exposure affects erbB2/Akt signal and reduces rat mammary tumorigenesis.

Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20100301

Title: TIMP-2 modulates VEGFR-2 phosphorylation and enhances phosphodiesterase activity in endothelial cells.

Journal: Laboratory investigation; a journal of technical methods and pathology 20100301

Title: APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis.

Journal: Brain structure & function 20100301

Title: Effect of paraquat-induced oxidative stress on insulin regulation of insulin-like growth factor-binding protein-1 gene expression.

Journal: Journal of clinical biochemistry and nutrition 20100301

Title: Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response.

Journal: PLoS biology 20100301

Title: Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk.

Journal: PLoS genetics 20100301

Title: Helicobacter pylori lipopolysaccharide is synthesized via a novel pathway with an evolutionary connection to protein N-glycosylation.

Journal: PLoS pathogens 20100301

Title: Appl1 is dispensable for mouse development, and loss of Appl1 has growth factor-selective effects on Akt signaling in murine embryonic fibroblasts.

Journal: The Journal of biological chemistry 20100226

Title: Alpha2,6-sialic acid on platelet endothelial cell adhesion molecule (PECAM) regulates its homophilic interactions and downstream antiapoptotic signaling.

Journal: The Journal of biological chemistry 20100226

Title: A novel Thr56Met mutation of the autosomal recessive hypercholesterolemia gene associated with hypercholesterolemia.

Journal: Journal of atherosclerosis and thrombosis 20100226

Title: Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation.

Journal: Molecular cell 20100226

Title: Roles of the intramolecular regions of FE65 in its trans-accumulation and in p53 stabilization in the nuclear matrix of osmotically stressed cells.

Journal: FEBS letters 20100219

Title: Bacterial pleckstrin homology domains: a prokaryotic origin for the PH domain.

Journal: Journal of molecular biology 20100212

Title: Major role of epidermal growth factor receptor and Src kinases in promoting oxidative stress-dependent loss of adhesion and apoptosis in epithelial cells.

Journal: The Journal of biological chemistry 20100212

Title: Phosphotyrosine confers client specificity to Hsp90.

Journal: Molecular cell 20100212

Title: Activity and cellular localization of an oncogenic glioblastoma multiforme-associated EGF receptor mutant possessing a duplicated kinase domain.

Journal: Oncogene 20100211

Title: Proteomic analysis of Src family kinases signaling complexes in Golgi/endosomal fractions using a site-selective anti-phosphotyrosine antibody: identification of LRP1-insulin receptor complexes.

Journal: Journal of proteome research 20100205

Title: Induction of myeloproliferative disorder and myelofibrosis by thrombopoietin receptor W515 mutants is mediated by cytosolic tyrosine 112 of the receptor.

Journal: Blood 20100204

Title: Na+/K+ATPase regulates sperm capacitation through a mechanism involving kinases and redistribution of its testis-specific isoform.

Journal: Molecular reproduction and development 20100201

Title: Performance metrics for liquid chromatography-tandem mass spectrometry systems in proteomics analyses.

Journal: Molecular & cellular proteomics : MCP 20100201

Title: Protein tyrosine phosphatases in glioma biology.

Journal: Acta neuropathologica 20100201

Title: Quantifying oncogenic phosphotyrosine signaling networks through systems biology.

Journal: Current opinion in genetics & development 20100201

Title: The Wnt pathway controls cell death engulfment, spindle orientation, and migration through CED-10/Rac.

Journal: PLoS biology 20100201

Title: The Syk kinase SmTK4 of Schistosoma mansoni is involved in the regulation of spermatogenesis and oogenesis.

Journal: PLoS pathogens 20100201

Title: A novel pseudopodial component of the dendritic cell anti-fungal response: the fungipod.

Journal: PLoS pathogens 20100201

Title: Dual specificity phosphatase16 is a negative regulator of c-Jun NH2-terminal kinase activity in T cells.

Journal: Microbiology and immunology 20100201

Title: Peptide-based activity-based probes (ABPs) for target-specific profiling of protein tyrosine phosphatases (PTPs).

Journal: Chemical communications (Cambridge, England) 20100128

Title: Amlodipine, a Ca2+ channel blocker, suppresses phosphorylation of epidermal growth factor receptor in human epidermoid carcinoma A431 cells.

Journal: Life sciences 20100116

Title: Identification of beta-catenin as a target of the intracellular tyrosine kinase PTK6.

Journal: Journal of cell science 20100115

Title: The somatostatin analogue octreotide confers sensitivity to rapamycin treatment on pituitary tumor cells.

Journal: Cancer research 20100115

Title: Prognostic effect of activated EGFR expression in human colon carcinomas: comparison with EGFR status.

Journal: British journal of cancer 20100105

Title: The involvement of suppressors of cytokine signaling 2 (SOCS2) in immune defense responses of Chinese mitten crab Eriocheir sinensis.

Journal: Developmental and comparative immunology 20100101

Title: Individual domains of Tensin2 exhibit distinct subcellular localisations and migratory effects.

Journal: The international journal of biochemistry & cell biology 20100101

Title: The effect of anti-eppin antibodies on ionophore A23187-induced calcium influx and acrosome reaction of human spermatozoa.

Journal: Human reproduction (Oxford, England) 20100101

Title: Apoptosis induction in BEFV-infected Vero and MDBK cells through Src-dependent JNK activation regulates caspase-3 and mitochondria pathways.

Journal: Veterinary research 20100101

Title: Cancer systems biology: a network modeling perspective.

Journal: Carcinogenesis 20100101

Title: Reactive oxygen species are signalling molecules for skeletal muscle adaptation.

Journal: Experimental physiology 20100101

Title: Functional characterization of the kinase activation loop in nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) using tandem affinity purification and liquid chromatography-mass spectrometry.

Journal: The Journal of biological chemistry 20100101

Title: Alpha5beta1 integrin engagement increases large conductance, Ca2+-activated K+ channel current and Ca2+ sensitivity through c-src-mediated channel phosphorylation.

Journal: The Journal of biological chemistry 20100101

Title: Antioxidant-induced phosphorylation of tyrosine 486 leads to rapid nuclear export of Bach1 that allows Nrf2 to bind to the antioxidant response element and activate defensive gene expression.

Journal: The Journal of biological chemistry 20100101

Title: Functional and structural characterization of the talin F0F1 domain.

Journal: Biochemical and biophysical research communications 20100101

Title: Targeting the epidermal growth factor receptor in epithelial ovarian cancer: current knowledge and future challenges.

Journal: Journal of oncology 20100101

Title: Toxicological disruption of signaling homeostasis: tyrosine phosphatases as targets.

Journal: Annual review of pharmacology and toxicology 20100101

Title: Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase.

Journal: BMC cancer 20100101

Title: Mechanism of attenuation of leptin signaling under chronic ligand stimulation.

Journal: BMC biochemistry 20100101

Title: Transcriptomic profiling of bovine IVF embryos revealed candidate genes and pathways involved in early embryonic development.

Journal: BMC genomics 20100101

Title: Novel role of phosphorylation-dependent interaction between FtsZ and FipA in mycobacterial cell division.

Journal: PloS one 20100101

Title: Cell aggregation induces phosphorylation of PECAM-1 and Pyk2 and promotes tumor cell anchorage-independent growth.

Journal: Molecular cancer 20100101

Title: Differential requirement of the epidermal growth factor receptor for G protein-mediated activation of transcription factors by lysophosphatidic acid.

Journal: Molecular cancer 20100101

Title: Identification of calcium-binding proteins associated with the human sperm plasma membrane.

Journal: Reproductive biology and endocrinology : RB&E 20100101

Title: Identification of possible targets of the Aspergillus fumigatus CRZ1 homologue, CrzA.

Journal: BMC microbiology 20100101

Title: Marburg virus evades interferon responses by a mechanism distinct from ebola virus.

Journal: PLoS pathogens 20100101

Title: Cooperativity within proximal phosphorylation sites is revealed from large-scale proteomics data.

Journal: Biology direct 20100101

Title: Protein tyrosine phosphatase 1B gene polymorphisms and essential hypertension: a case-control study in Chinese population.

Journal: Journal of endocrinological investigation 20100101

Title: Lineage-specific co-evolution of the Egf receptor/ligand signaling system.

Journal: BMC evolutionary biology 20100101

Title: CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases.

Journal: PloS one 20100101

Title: Vertebrate Lrig3-ErbB interactions occur in vitro but are unlikely to play a role in Lrig3-dependent inner ear morphogenesis.

Journal: PloS one 20100101

Title: Biochemical profiling of histone binding selectivity of the yeast bromodomain family.

Journal: PloS one 20100101

Title: Site-directed mutagenesis reveals a unique requirement for tyrosine residues in IL-7Ralpha and TSLPR cytoplasmic domains in TSLP-dependent cell proliferation.

Journal: BMC immunology 20100101

Title: Posttranslational modifications, localization, and protein interactions of optineurin, the product of a glaucoma gene.

Journal: PloS one 20100101

Title: Dystroglycan versatility in cell adhesion: a tale of multiple motifs.

Journal: Cell communication and signaling : CCS 20100101

Title: Exposure of beta-tubulin regions defined by antibodies on an Arabidopsis thaliana microtubule protofilament model and in the cells.

Journal: BMC plant biology 20100101

Title: IL-9 induces CCL11 expression via STAT3 signalling in human airway smooth muscle cells.

Journal: PloS one 20100101

Title: Angiotensin II type 2 receptor signaling significantly attenuates growth of murine pancreatic carcinoma grafts in syngeneic mice.

Journal: BMC cancer 20100101

Title: Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease.

Journal: Molecular neurodegeneration 20100101

Title: The structural insights of stem cell factor receptor (c-Kit) interaction with tyrosine phosphatase-2 (Shp-2): an in silico analysis.

Journal: BMC research notes 20100101

Title: Mass spectrometric analysis of Ehrlichia chaffeensis tandem repeat proteins reveals evidence of phosphorylation and absence of glycosylation.

Journal: PloS one 20100101

Title: Masitinib combined with standard gemcitabine chemotherapy: in vitro and in vivo studies in human pancreatic tumour cell lines and ectopic mouse model.

Journal: PloS one 20100101

Title: Developmental and oncogenic effects of insulin-like growth factor-I in Ptc1+/- mouse cerebellum.

Journal: Molecular cancer 20100101

Title: High-throughput kinase assay based on surface plasmon resonance.

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Phosphotyrosine phosphatases in cancer diagnostic and treatment.

Journal: Recent patents on DNA & gene sequences 20100101

Title: Comparative genomics and proteomics of Helicobacter mustelae, an ulcerogenic and carcinogenic gastric pathogen.

Journal: BMC genomics 20100101

Title: Role of prostaglandin E receptor subtypes EP2 and EP4 in autocrine and paracrine functions of vascular endothelial growth factor in the inner ear.

Journal: BMC neuroscience 20100101

Title: The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathways.

Journal: PloS one 20100101

Title: Insulin receptor signaling in the development of neuronal structure and function.

Journal: Neural development 20100101

Title: Stoichiometry and intracellular fate of TRIM-containing TCR complexes.

Journal: Cell communication and signaling : CCS 20100101

Title: Adhesion of monocytes to type I collagen stimulates an APP-dependent proinflammatory signaling response and release of Abeta1-40.

Journal: Journal of neuroinflammation 20100101

Title: T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.

Journal: PloS one 20100101

Title: Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation.

Journal: PloS one 20100101

Title: Tiam1 as a signaling mediator of nerve growth factor-dependent neurite outgrowth.

Journal: PloS one 20100101

Title: Hepatitis B virus X protein impairs hepatic insulin signaling through degradation of IRS1 and induction of SOCS3.

Journal: PloS one 20100101

Title: In the absence of frazzled over-expression of Abelson tyrosine kinase disrupts commissure formation and causes axons to leave the embryonic CNS.

Journal: PloS one 20100101

Title: Structural and functional studies of STAT1 from Atlantic salmon (Salmo salar).

Journal: BMC immunology 20100101

Title: Quantifying protein-protein interactions in high throughput using protein domain microarrays.

Journal: Nature protocols 20100101

Title: Arabidopsis thaliana GYRB3 does not encode a DNA gyrase subunit.

Journal: PloS one 20100101

Title: Characterization of trophoblast and extraembryonic endoderm cell lineages derived from rat preimplantation embryos.

Journal: PloS one 20100101

Title: Applying mass spectrometry based proteomic technology to advance the understanding of multiple myeloma.

Journal: Journal of hematology & oncology 20100101

Title: Effects of (-)-epigallocatechin gallate on RPE cell migration and adhesion.

Journal: Molecular vision 20100101

Title: Vasectomy affects cysteine-rich secretory protein expression along the human epididymis and its association with ejaculated spermatozoa following vasectomy surgical reversal.

Journal: Journal of andrology 20100101

Title: Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy.

Journal: Molecular cancer 20100101

Title: Leishmania interferes with host cell signaling to devise a survival strategy.

Journal: Journal of biomedicine & biotechnology 20100101

Title: Key signalling nodes in mammary gland development and cancer. Signalling downstream of PI3 kinase in mammary epithelium: a play in 3 Akts.

Journal: Breast cancer research : BCR 20100101

Title: Binding-site assessment by virtual fragment screening.

Journal: PloS one 20100101

Title: PI3Kp110-, Src-, FAK-dependent and DOCK2-independent migration and invasion of CXCL13-stimulated prostate cancer cells.

Journal: Molecular cancer 20100101

Title: Hypoxia induces differential translation of enolase/MBP-1.

Journal: BMC cancer 20100101

Title: Critical role of FLRT1 phosphorylation in the interdependent regulation of FLRT1 function and FGF receptor signalling.

Journal: PloS one 20100101

Title: Extracellular SOD-derived H2O2 promotes VEGF signaling in caveolae/lipid rafts and post-ischemic angiogenesis in mice.

Journal: PloS one 20100101

Title: A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist.

Journal: PloS one 20100101

Title: PhosphoGRID: a database of experimentally verified in vivo protein phosphorylation sites from the budding yeast Saccharomyces cerevisiae.

Journal: Database : the journal of biological databases and curation 20100101

Title: In vivo tumor cell adhesion in the pulmonary microvasculature is exclusively mediated by tumor cell--endothelial cell interaction.

Journal: BMC cancer 20100101

Title: Spatio-temporal modeling of signaling protein recruitment to EGFR.

Journal: BMC systems biology 20100101

Title: A novel synthetic analog of 5, 8-disubstituted quinazolines blocks mitosis and induces apoptosis of tumor cells by inhibiting microtubule polymerization.

Journal: PloS one 20100101

Title: Stat3: linking inflammation to epithelial cancer - more than a 'gut' feeling?

Journal: Cell division 20100101

Title: Fluoride effects: the two faces of janus.

Journal: Current medicinal chemistry 20100101

Title: The dawn of a new era in cell signalling research.

Journal: Cell communication and signaling : CCS 20100101

Title: Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition.

Journal: Molecular cancer 20100101

Title: Prolonged activation of S6K1 does not suppress IRS or PI-3 kinase signaling during muscle cell differentiation.

Journal: BMC cell biology 20100101

Title: Arecoline induces HA22T/VGH hepatoma cells to undergo anoikis - involvement of STAT3 and RhoA activation.

Journal: Molecular cancer 20100101

Title: PDZ domains and their binding partners: structure, specificity, and modification.

Journal: Cell communication and signaling : CCS 20100101

Title: Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics.

Journal: Molecular cancer 20100101

Title: Understanding the role of PknJ in Mycobacterium tuberculosis: biochemical characterization and identification of novel substrate pyruvate kinase A.

Journal: PloS one 20100101

Title: Vicrostatin - an anti-invasive multi-integrin targeting chimeric disintegrin with tumor anti-angiogenic and pro-apoptotic activities.

Journal: PloS one 20100101

Title: Structural and dynamical effects induced by the anticancer drug topotecan on the human topoisomerase I - DNA complex.

Journal: PloS one 20100101

Title: Factors that may impact on immunosenescence: an appraisal.

Journal: Immunity & ageing : I & A 20100101

Title: Phosphorylation State-Dependent High Throughput Screening of the c-Met Kinase.

Journal: Current chemical genomics 20100101

Title: Etk/Bmx regulates proteinase-activated-receptor1 (PAR1) in breast cancer invasion: signaling partners, hierarchy and physiological significance.

Journal: PloS one 20100101

Title: YopH inhibits early pro-inflammatory cytokine responses during plague pneumonia.

Journal: BMC immunology 20100101

Title: The phosphatomes of the multicellular myxobacteria Myxococcus xanthus and Sorangium cellulosum in comparison with other prokaryotic genomes.

Journal: PloS one 20100101

Title: Conformational determinants of phosphotyrosine peptides complexed with the Src SH2 domain.

Journal: PloS one 20100101

Title: Low doses of ionizing radiation promote tumor growth and metastasis by enhancing angiogenesis.

Journal: PloS one 20100101

Title: The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor.

Journal: Cell communication and signaling : CCS 20100101

Title: A novel mechanism of cell growth regulation by Cell Cycle and Apoptosis Regulatory Protein (CARP)-1.

Journal: Journal of molecular signaling 20100101

Title: A new approach to comparing anti-CD20 antibodies: importance of the lipid rafts in their lytic efficiency.

Journal: OncoTargets and therapy 20100101

Title: Nm23-H1 suppresses hepatocarcinoma cell adhesion and migration on fibronectin by modulating glycosylation of integrin beta1.

Journal: Journal of experimental & clinical cancer research : CR 20100101

Title: Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression.

Journal: Molecular cancer 20100101

Title: Gonadotropin-releasing hormone type II antagonist induces apoptosis in MCF-7 and triple-negative MDA-MB-231 human breast cancer cells in vitro and in vivo.

Journal: Breast cancer research : BCR 20100101

Title: Motesanib inhibits Kit mutations associated with gastrointestinal stromal tumors.

Journal: Journal of experimental & clinical cancer research : CR 20100101

Title: Protein phosphatase complement in rice: genome-wide identification and transcriptional analysis under abiotic stress conditions and reproductive development.

Journal: BMC genomics 20100101

Title: Neural membrane signaling platforms.

Journal: International journal of molecular sciences 20100101

Title: Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production.

Journal: PloS one 20100101

Title: Thy-1 attenuates TNF-alpha-activated gene expression in mouse embryonic fibroblasts via Src family kinase.

Journal: PloS one 20100101

Title: Transactivation of PDGFRbeta by dopamine D4 receptor does not require PDGFRbeta dimerization.

Journal: Molecular brain 20100101

Title: A limited role for PI(3,4,5)P3 regulation in controlling skeletal muscle mass in response to resistance exercise.

Journal: PloS one 20100101

Title: Adhesion and degranulation promoting adapter protein (ADAP) is a central hub for phosphotyrosine-mediated interactions in T cells.

Journal: PloS one 20100101

Title: Gene expression analysis after receptor tyrosine kinase activation reveals new potential melanoma proteins.

Journal: BMC cancer 20100101

Title: Gene expression profile of epithelial cells and mesenchymal cells derived from limbal explant culture.

Journal: Molecular vision 20100101

Title: A genetic screen for anchorage-independent proliferation in mammalian cells identifies a membrane-bound neuregulin.

Journal: PloS one 20100101

Title: Personalized therapies in the cancer 'omics' era.

Journal: Molecular cancer 20100101

Title: A new family of phosphoinositide phosphatases in microorganisms: identification and biochemical analysis.

Journal: BMC genomics 20100101

Title: Peptidomimetic competitive inhibitors of protein tyrosine phosphatases.

Journal: Current pharmaceutical design 20100101

Title: EPO receptor gain-of-function causes hereditary polycythemia, alters CD34 cell differentiation and increases circulating endothelial precursors.

Journal: PloS one 20100101

Title: Fluidization and resolidification of the human bladder smooth muscle cell in response to transient stretch.

Journal: PloS one 20100101

Title: Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death.

Journal: Experimental & translational stroke medicine 20100101

Title: Interleukin-27 acts on hepatic stellate cells and induces signal transducer and activator of transcription 1-dependent responses.

Journal: Cell communication and signaling : CCS 20100101

Title: Microglial immunoreceptor tyrosine-based activation and inhibition motif signaling in neuroinflammation.

Journal: International journal of Alzheimer's disease 20100101

Title: The activation of Proteinase-Activated Receptor-1 (PAR1) mediates gastric cancer cell proliferation and invasion.

Journal: BMC cancer 20100101

Title: Suppression of uPA and uPAR attenuates angiogenin mediated angiogenesis in endothelial and glioblastoma cell lines.

Journal: PloS one 20100101

Title: Dasatinib synergizes with JSI-124 to inhibit growth and migration and induce apoptosis of malignant human glioma cells.

Journal: Journal of carcinogenesis 20100101

Title: Partitioning of minimotifs based on function with improved prediction accuracy.

Journal: PloS one 20100101

Title: Molecular mechanistic associations of human diseases.

Journal: BMC systems biology 20100101

Title: Ephrin-A5 and EphA5 interaction induces synaptogenesis during early hippocampal development.

Journal: PloS one 20100101

Title: Menin and RNF20 recruitment is associated with dynamic histone modifications that regulate signal transducer and activator of transcription 1 (STAT1)-activated transcription of the interferon regulatory factor 1 gene (IRF1).

Journal: Epigenetics & chromatin 20100101

Title: Experimental assessment of pro-lymphangiogenic growth factors in the treatment of post-surgical lymphedema following lymphadenectomy.

Journal: Breast cancer research : BCR 20100101

Title: The role of the JAK2-STAT3 pathway in pro-inflammatory responses of EMF-stimulated N9 microglial cells.

Journal: Journal of neuroinflammation 20100101

Title: Calcium regulation of EGF-induced ERK5 activation: role of Lad1-MEKK2 interaction.

Journal: PloS one 20100101

Title: Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain.

Journal: Molecular neurodegeneration 20100101

Title: CXCL10 can inhibit endothelial cell proliferation independently of CXCR3.

Journal: PloS one 20100101

Title: Isolation of detergent resistant microdomains from cultured neurons: detergent dependent alterations in protein composition.

Journal: BMC neuroscience 20100101

Title: PeptideMine--a webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactomes.

Journal: BMC bioinformatics 20100101

Title: Additional serine/threonine phosphorylation reduces binding affinity but preserves interface topography of substrate proteins to the c-Cbl TKB domain.

Journal: PloS one 20100101

Title: Integrated ligand-receptor bioinformatic and in vitro functional analysis identifies active TGFA/EGFR signaling loop in papillary thyroid carcinomas.

Journal: PloS one 20100101

Title: Quantitative phosphoproteomic analysis of prion-infected neuronal cells.

Journal: Cell communication and signaling : CCS 20100101

Title: The DNA relaxation activity and covalent complex accumulation of Mycobacterium tuberculosis topoisomerase I can be assayed in Escherichia coli: application for identification of potential FRET-dye labeling sites.

Journal: BMC biochemistry 20100101

Title: Mechanical stress activates Smad pathway through PKCδ to enhance interleukin-11 gene transcription in osteoblasts.

Journal: PloS one 20100101

Title: Quantitative phosphoproteomics of proteasome inhibition in multiple myeloma cells.

Journal: PloS one 20100101

Title: The role of the focal adhesion protein PINCH1 for the radiosensitivity of adhesion and suspension cell cultures.

Journal: PloS one 20100101

Title: Epigenetic regulation of CpG promoter methylation in invasive prostate cancer cells.

Journal: Molecular cancer 20100101

Title: Interaction of human dipeptidyl peptidase IV and human immunodeficiency virus type-1 transcription transactivator in Sf9 cells.

Journal: Virology journal 20100101

Title: Differential genetic regulation of canine hip dysplasia and osteoarthritis.

Journal: PloS one 20100101

Title: SH2 modified STAT1 induces HLA-I expression and improves IFN-γ signaling in IFN-α resistant HCV replicon cells.

Journal: PloS one 20100101

Title: Dasatinib reduces FAK phosphorylation increasing the effects of RPI-1 inhibition in a RET/PTC1-expressing cell line.

Journal: Molecular cancer 20100101

Title: Identification of tetranectin as a potential biomarker for metastatic oral cancer.

Journal: International journal of molecular sciences 20100101

Title: Chimeric design, synthesis, and biological assays of a new nonpeptide insulin-mimetic vanadium compound to inhibit protein tyrosine phosphatase 1B.

Journal: Drug design, development and therapy 20100101

Title: Tyrosine phosphorylation of Grb14 by Tie2.

Journal: Cell communication and signaling : CCS 20100101

Title: Characterizing tyrosine phosphorylation signaling in lung cancer using SH2 profiling.

Journal: PloS one 20100101

Title: Hypercholesterolemia impaired sperm functionality in rabbits.

Journal: PloS one 20100101

Title: Proteins involved in platelet signaling are differentially regulated in acute coronary syndrome: a proteomic study.

Journal: PloS one 20100101

Title: Growth factor regulation of proliferation and survival of multipotential stromal cells.

Journal: Stem cell research & therapy 20100101

Title: A Toll-like receptor-responsive kinase, protein kinase R, is inactivated in endotoxin tolerance through differential K63/K48 ubiquitination.

Journal: mBio 20100101

Title: Regulation of Ack1 localization and activity by the amino-terminal SAM domain.

Journal: BMC biochemistry 20100101

Title: Z-360, a novel therapeutic agent for pancreatic cancer, prevents up-regulation of ephrin B1 gene expression and phosphorylation of NR2B via suppression of interleukin-1 β production in a cancer-induced pain model in mice.

Journal: Molecular pain 20100101

Title: Genistein attenuates retinal inflammation associated with diabetes by targeting of microglial activation.

Journal: Molecular vision 20100101

Title: Profiling Y561-dependent and -independent substrates of CSF-1R in epithelial cells.

Journal: PloS one 20100101

Title: Characterization of in vivo keratin 19 phosphorylation on tyrosine-391.

Journal: PloS one 20100101

Title: Palmitate and insulin synergistically induce IL-6 expression in human monocytes.

Journal: Cardiovascular diabetology 20100101

Title: Characterization of human platelet binding of recombinant T cell receptor ligand.

Journal: Journal of neuroinflammation 20100101

Title: Role of the VEGF-Flt-1-FAK pathway in the pathogenesis of osteoclastic bone destruction of giant cell tumors of bone.

Journal: Journal of orthopaedic surgery and research 20100101

Title: FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy.

Journal: PloS one 20100101

Title: Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects.

Journal: PloS one 20100101

Title: Mitochondrial tyrosine phosphoproteome: new insights from an up-to-date analysis.

Journal: BioFactors (Oxford, England) 20100101

Title: Versican G3 promotes mouse mammary tumor cell growth, migration, and metastasis by influencing EGF receptor signaling.

Journal: PloS one 20100101

Title: Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells.

Journal: Breast cancer research : BCR 20100101

Title: Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling.

Journal: PloS one 20100101

Title: Clinical application for the preservation of phospho-proteins through in-situ tissue stabilization.

Journal: Proteome science 20100101

Title: RhoH regulates subcellular localization of ZAP-70 and Lck in T cell receptor signaling.

Journal: PloS one 20100101

Title: Reactive oxygen species are required for maintenance and differentiation of primary lung fibroblasts in idiopathic pulmonary fibrosis.

Journal: PloS one 20100101

Title: Deletion or insertion in the first immunoglobulin-plexin-transcription (IPT) domain differentially regulates expression and tumorigenic activities of RON receptor Tyrosine Kinase.

Journal: Molecular cancer 20100101

Title: Two novel human NUMB isoforms provide a potential link between development and cancer.

Journal: Neural development 20100101

Title: The Fer tyrosine kinase regulates interactions of Rho GDP-Dissociation Inhibitor α with the small GTPase Rac.

Journal: BMC biochemistry 20100101

Title: The kinome of Phytophthora infestans reveals oomycete-specific innovations and links to other taxonomic groups.

Journal: BMC genomics 20100101

Title: XAF1 expression and regulatory effects of somatostatin on XAF1 in prostate cancer cells.

Journal: Journal of experimental & clinical cancer research : CR 20100101

Title: Cdk1 and SUMO regulate Swe1 stability.

Journal: PloS one 20100101

Title: Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src.

Journal: PloS one 20100101

Title: T cell receptor signal initiation induced by low-grade stimulation requires the cooperation of LAT in human T cells.

Journal: PloS one 20100101

Title: Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression.

Journal: PloS one 20100101

Title: Trace elements in glucometabolic disorders: an update.

Journal: Diabetology & metabolic syndrome 20100101

Title: CSPG is a secreted factor that stimulates neural stem cell survival possibly by enhanced EGFR signaling.

Journal: PloS one 20100101

Title: Matched sizes of activating and inhibitory receptor/ligand pairs are required for optimal signal integration by human natural killer cells.

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Title: Phosphorylation meets nuclear import: a review.

Journal: Cell communication and signaling : CCS 20100101

Title: A serum factor induces insulin-independent translocation of GLUT4 to the cell surface which is maintained in insulin resistance.

Journal: PloS one 20100101

Title: Role of lapatinib in the first-line treatment of patients with metastatic breast cancer.

Journal: Cancer management and research 20100101

Title: Role of erlotinib in first-line and maintenance treatment of advanced non-small-cell lung cancer.

Journal: Cancer management and research 20100101

Title: Ligand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cells.

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Title: Endotoxin mediated-iNOS induction causes insulin resistance via ONOO⁻ induced tyrosine nitration of IRS-1 in skeletal muscle.

Journal: PloS one 20100101

Title: Glycolipid-Dependent, Protease Sensitive Internalization of Pseudomonas aeruginosa Into Cultured Human Respiratory Epithelial Cells.

Journal: The open microbiology journal 20100101

Title: c-Abl phosphorylation of ΔNp63α is critical for cell viability.

Journal: Cell death & disease 20100101

Title: c-Abl downregulates the slow phase of double-strand break repair.

Journal: Cell death & disease 20100101

Title: Protein microarrays and biomarkers of infectious disease.

Journal: International journal of molecular sciences 20100101

Title: Exploitation of host cell biology and evasion of immunity by francisella tularensis.

Journal: Frontiers in microbiology 20100101

Title: Adherence to and invasion of host cells by spotted Fever group rickettsia species.

Journal: Frontiers in microbiology 20100101

Title: The role of somatostatin in 67 consecutive pancreatectomies: a randomized clinical trial.

Journal: Clinical and experimental gastroenterology 20100101

Title: Studies of Antimicrobial Activities of some 4-Thiazolidinone Fused Pyrimidines, [1,5]-Benzodiazepines and their Oxygen Substituted Hydroxylamine Derivatives.

Journal: Indian journal of pharmaceutical sciences 20100101

Title: QSAR studies of benzofuran/benzothiophene biphenyl derivatives as inhibitors of PTPase-1B.

Journal: Journal of pharmacy & bioallied sciences 20100101

Title: Proteasomal Degradation of Indoleamine 2,3-Dioxygenase in CD8 Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3).

Journal: International journal of tryptophan research : IJTR 20100101

Title: Design strategies of fluorescent biosensors based on biological macromolecular receptors.

Journal: Sensors (Basel, Switzerland) 20100101

Title: Secondary metabolites as DNA topoisomerase inhibitors: A new era towards designing of anticancer drugs.

Journal: Pharmacognosy reviews 20100101

Title: Stress sensors and signal transducers in cyanobacteria.

Journal: Sensors (Basel, Switzerland) 20100101

Title: Environmentally sensitive fluorescent sensors based on synthetic peptides.

Journal: Sensors (Basel, Switzerland) 20100101

Title: Molecular basis of Mammalian embryonic stem cell pluripotency and self-renewal.

Journal: Acta naturae 20100101

Title: Proteases that can distinguish among different post-translational forms of tyrosine engineered using multicolor flow cytometry.

Journal: Journal of the American Chemical Society 20091223

Title: Epidermal growth factor receptor expression escapes androgen regulation in prostate cancer: a potential molecular switch for tumour growth.

Journal: British journal of cancer 20091215

Title: Cell-specific information processing in segregating populations of Eph receptor ephrin-expressing cells.

Journal: Science (New York, N.Y.) 20091211

Title: Crystallographic insight into collagen recognition by discoidin domain receptor 2.

Journal: Structure (London, England : 1993) 20091209

Title: Modulation of human gingival fibroblast adhesion, morphology, tyrosine phosphorylation, and ERK 1/2 localization on polished, grooved and SLA substratum topographies.

Journal: Journal of biomedical materials research. Part A 20091201

Title: Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics.

Journal: Molecular & cellular proteomics : MCP 20091201

Title: Phosphoproteomics of Klebsiella pneumoniae NTUH-K2044 reveals a tight link between tyrosine phosphorylation and virulence.

Journal: Molecular & cellular proteomics : MCP 20091201

Title: EGFR tyrosine kinase inhibitor (PD153035) improves glucose tolerance and insulin action in high-fat diet-fed mice.

Journal: Diabetes 20091201

Title: Sphingosine-1-phosphate effects on the inner wall of Schlemm's canal and outflow facility in perfused human eyes.

Journal: Experimental eye research 20091201

Title: Phosphotyrosine protein dynamics in cell membrane rafts of sphingosine-1-phosphate-stimulated human endothelium: role in barrier enhancement.

Journal: Cellular signalling 20091201

Title: Urotensin II induces rat cardiomyocyte hypertrophy via the transient oxidization of Src homology 2-containing tyrosine phosphatase and transactivation of epidermal growth factor receptor.

Journal: Molecular pharmacology 20091201

Title: Protein tyrosine kinase involvement in learning-produced changes in Hermissenda type B photoreceptors.

Journal: Journal of neurophysiology 20091201

Title: Time-resolved observation of product ions generated by 157 nm photodissociation of singly protonated phosphopeptides.

Journal: Journal of the American Society for Mass Spectrometry 20091201

Title: Molecular imaging of gefitinib activity in an epidermal growth factor receptor (EGFR)-bearing xenograft model.

Journal: Cancer biology & therapy 20091201

Title: Endosomal proteolysis of internalised [ArgA0]-human insulin at neutral pH generates the mature insulin peptide in rat liver in vivo.

Journal: Diabetologia 20091201

Title: Involvement of the c-jun N-terminal kinases JNK1 and JNK2 in complement-mediated cell death.

Journal: Molecular immunology 20091201

Title: Comparison of protein expression in two prostate cancer cell-lines, LNCaP and DU145, after treatment with somatostatin.

Journal: Oncology reports 20091201

Title: Ultraviolet photodissociation at 266 nm of phosphorylated peptide cations.

Journal: Rapid communications in mass spectrometry : RCM 20091201

Title: Beryllium alters lipopolysaccharide-mediated intracellular phosphorylation and cytokine release in human peripheral blood mononuclear cells.

Journal: Journal of occupational and environmental hygiene 20091201

Title: Inhibiton of RET and JAK2 signals and upregulation of VEGFR3 phosphorylation in vitro by galectin-1 in trophoblast tumor cells BeWo.

Journal: Placenta 20091201

Title: SH2 domains: modulators of nonreceptor tyrosine kinase activity.

Journal: Current opinion in structural biology 20091201

Title: Helicobacter pylori type IV secretion apparatus exploits beta1 integrin in a novel RGD-independent manner.

Journal: PLoS pathogens 20091201

Title: Biology of urothelial tumorigenesis: insights from genetically engineered mice.

Journal: Cancer metastasis reviews 20091201

Title: Swiprosin-1 Regulates Cytokine Expression of Human Mast Cell Line HMC-1 through Actin Remodeling.

Journal: Immune network 20091201

Title: Incorporating support vector machine for identifying protein tyrosine sulfation sites.

Journal: Journal of computational chemistry 20091130

Title: Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity.

Journal: Blood 20091126

Title: PECAM-1 expression and activity negatively regulate multiple platelet signaling pathways.

Journal: FEBS letters 20091119

Title: Amyloid precursor protein mediates a tyrosine kinase-dependent activation response in endothelial cells.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20091118

Title: Activity of the multikinase inhibitor dasatinib against ovarian cancer cells.

Journal: British journal of cancer 20091117

Title: A reciprocal interdependence between Nck and PI(4,5)P(2) promotes localized N-WASp-mediated actin polymerization in living cells.

Journal: Molecular cell 20091113

Title: Characterization of a novel focal adhesion kinase inhibitor in human platelets.

Journal: Biochemical and biophysical research communications 20091106

Title: Embryogenesis: Degenerate phosphatases control the oocyte-to-embryo transition.

Journal: Current biology : CB 20091103

Title: Recombinant human epidermal growth factor treatment of radiation-induced severe oral mucositis in patients with head and neck malignancies.

Journal: European journal of cancer care 20091101

Title: The interaction of estrogen receptor alpha and caveolin-3 regulates connexin43 phosphorylation in metabolic inhibition-treated rat cardiomyocytes.

Journal: The international journal of biochemistry & cell biology 20091101

Title: Differential 14-3-3 affinity capture reveals new downstream targets of phosphatidylinositol 3-kinase signaling.

Journal: Molecular & cellular proteomics : MCP 20091101

Title: Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex.

Journal: The Biochemical journal 20091101

Title: Nutrient stress activates inflammation and reduces glucose metabolism by suppressing AMP-activated protein kinase in the heart.

Journal: Diabetes 20091101

Title: Proteomic, functional and motif-based analysis of C-terminal Src kinase-interacting proteins.

Journal: Proteomics 20091101

Title: Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3.

Journal: Carcinogenesis 20091101

Title: STEAP4 regulates focal adhesion kinase activation and CpG motifs within STEAP4 promoter region are frequently methylated in DU145, human androgen-independent prostate cancer cells.

Journal: International journal of molecular medicine 20091101

Title: Impaired fibroblast growth factor receptor 1 signaling as a cause of normosmic idiopathic hypogonadotropic hypogonadism.

Journal: The Journal of clinical endocrinology and metabolism 20091101

Title: FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20091101

Title: Phosphoinositide 3-kinase-regulated adapters in lymphocyte activation.

Journal: Immunological reviews 20091101

Title: Differential expression of CD3zeta message and protein in tumor infiltrating lymphocytes from solid tumor specimens and malignant ascites from patients with ovarian carcinoma.

Journal: Anticancer research 20091101

Title: Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts.

Journal: Blood 20091029

Title: PTEN and SHIP2 regulates PI3K/Akt pathway through focal adhesion kinase.

Journal: Molecular and cellular endocrinology 20091015

Title: Sam68 and ERKs regulate leptin-induced expression of OB-Rb mRNA in C2C12 myotubes.

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Title: fps/fes knockout mice display a lactation defect and the fps/fes tyrosine kinase is a component of E-cadherin-based adherens junctions in breast epithelial cells during lactation.

Journal: Experimental cell research 20091015

Title: Developmental switch in NF-kappaB signalling required for neurite growth.

Journal: Development (Cambridge, England) 20091015

Title: Tyrosine phosphorylation of nuclear-membrane protein emerin by Src, Abl and other kinases.

Journal: Journal of cell science 20091015

Title: A nuclear localization signal at the SAM-SAM domain interface of AIDA-1 suggests a requirement for domain uncoupling prior to nuclear import.

Journal: Journal of molecular biology 20091009

Title: Effects of VEGFR-3 phosphorylation inhibitor on lymph node metastasis in an orthotopic diffuse-type gastric carcinoma model.

Journal: British journal of cancer 20091006

Title: Tyrosine phosphorylation of neuronal nitric oxide synthase (nNOS) during hypoxia in the cerebral cortex of newborn piglets: the role of nitric oxide.

Journal: Neuroscience letters 20091002

Title: Semaphorin3A signaling mediated by Fyn-dependent tyrosine phosphorylation of collapsin response mediator protein 2 at tyrosine 32.

Journal: The Journal of biological chemistry 20091002

Title: A new role of anandamide in human sperm: focus on metabolism.

Journal: Journal of cellular physiology 20091001

Title: Atypical protein kinase C activity is required for extracellular matrix degradation and invasion by Src-transformed cells.

Journal: Journal of cellular physiology 20091001

Title: Increased MAPK activation and impaired insulin signaling in subcutaneous microvascular endothelial cells in type 2 diabetes: the role of endothelin-1.

Journal: Diabetes 20091001

Title: Proteomic analysis of integrin alphaIIbbeta3 outside-in signaling reveals Src-kinase-independent phosphorylation of Dok-1 and Dok-3 leading to SHIP-1 interactions.

Journal: Journal of thrombosis and haemostasis : JTH 20091001

Title: Essential involvement of the NMDA receptor in ethanol preconditioning-dependent neuroprotection from amyloid-betain vitro.

Journal: Journal of neurochemistry 20091001

Title: Involvement of protein kinase C and Src tyrosine kinase in acute tolerance to ethanol inhibition of spinal NMDA-induced pressor responses in rats.

Journal: British journal of pharmacology 20091001

Title: Amyloid precursor family proteins are expressed by thymic and lymph node stromal cells but are not required for lymphocyte development.

Journal: International immunology 20091001

Title: Brassinosteroid signal transduction from cell-surface receptor kinases to nuclear transcription factors.

Journal: Nature cell biology 20091001

Title: Is expression or activation of Src kinase associated with cancer-specific survival in ER-, PR- and HER2-negative breast cancer patients?

Journal: The American journal of pathology 20091001

Title: Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells.

Journal: PLoS pathogens 20091001

Title: Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM10.

Journal: PLoS biology 20091001

Title: Positive selection of tyrosine loss in metazoan evolution.

Journal: Science (New York, N.Y.) 20090925

Title: Crystal structures of Wzb of Escherichia coli and CpsB of Streptococcus pneumoniae, representatives of two families of tyrosine phosphatases that regulate capsule assembly.

Journal: Journal of molecular biology 20090925

Title: New activation modus of STAT3: a tyrosine-less region of the interleukin-22 receptor recruits STAT3 by interacting with its coiled-coil domain.

Journal: The Journal of biological chemistry 20090925

Title: Peptide-major histocompatibility complex dimensions control proximal kinase-phosphatase balance during T cell activation.

Journal: The Journal of biological chemistry 20090918

Title: Dopamine regulates phosphorylation of VEGF receptor 2 by engaging Src-homology-2-domain-containing protein tyrosine phosphatase 2.

Journal: Journal of cell science 20090915

Title: VEGFR2-PLCgamma1 axis is essential for endothelial specification of VEGFR2+ vascular progenitor cells.

Journal: Journal of cell science 20090915

Title: Increased protein stability of FGF1 can compensate for its reduced affinity for heparin.

Journal: The Journal of biological chemistry 20090911

Title: Lithium suppresses motility and invasivity of v-src-transformed cells by glutathione-dependent activation of phosphotyrosine phosphatases.

Journal: Oncogene 20090910

Title: CCM2 mediates death signaling by the TrkA receptor tyrosine kinase.

Journal: Neuron 20090910

Title: Post-transcriptional regulation of chemokine receptor CXCR4 by estrogen in HER2 overexpressing, estrogen receptor-positive breast cancer cells.

Journal: Breast cancer research and treatment 20090901

Title: Enhanced ex vivo expansion of human adipose tissue-derived mesenchymal stromal cells by fibroblast growth factor-2 and dexamethasone.

Journal: Tissue engineering. Part A 20090901

Title: Detection and analysis of protein histidine phosphorylation.

Journal: Molecular and cellular biochemistry 20090901

Title: Novel phosphotyrosine targets of FGFR2IIIb signaling.

Journal: Cellular signalling 20090901

Title: Expression of full-length and truncated Fyn tyrosine kinase transcripts and encoded proteins during spermatogenesis and localization during acrosome biogenesis and fertilization.

Journal: Molecular reproduction and development 20090901

Title: Growth hormone deficiency and antipituitary antibodies in a patient with common variable immunodeficiency.

Journal: Journal of endocrinological investigation 20090901

Title: Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041.

Journal: Molecular & cellular proteomics : MCP 20090901

Title: SH2B1 enhances insulin sensitivity by both stimulating the insulin receptor and inhibiting tyrosine dephosphorylation of insulin receptor substrate proteins.

Journal: Diabetes 20090901

Title: Phosphorylation and consequent stimulation of the tyrosine kinase c-Abl by PKA in mouse spermatozoa; its implications during capacitation.

Journal: Developmental biology 20090901

Title: Mirk/Dyrk1B, a novel therapeutic target, mediates cell survival in non-small cell lung cancer cells.

Journal: Cancer biology & therapy 20090901

Title: Tyrosine-phosphorylation of the 12th armadillo-repeat of beta-catenin is associated with cadherin dysfunction in human cancer.

Journal: International journal of oncology 20090901

Title: Group B Streptococcus induces tyrosine phosphorylation of annexin V and glutathione S-transferase in human umbilical vein endothelial cells.

Journal: International journal of molecular medicine 20090901

Title: CD137 ligand-mediated reverse signals increase cell viability and cytokine expression in murine myeloid cells: involvement of mTOR/p70S6 kinase and Akt.

Journal: European journal of immunology 20090901

Title: Differential regulation of type I interferon and epidermal growth factor pathways by a human Respirovirus virulence factor.

Journal: PLoS pathogens 20090901

Title: Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20090825

Title: Solid-phase synthesis of amino- and carboxyl-functionalized unnatural alpha-amino acid amides.

Journal: Organic letters 20090820

Title: Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signalling.

Journal: The EMBO journal 20090819

Title: Out of the box binding determines specificity of SH2 domain interaction.

Journal: Structure (London, England : 1993) 20090812

Title: The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site.

Journal: Cell 20090807

Title: Synthesis of phosphatase-stable, cell-permeable peptidomimetic prodrugs that target the SH2 domain of Stat3.

Journal: Organic letters 20090806

Title: Determination of AMP-activated protein kinase phosphorylation sites in recombinant protein expressed using the pET28a vector: a cautionary tale.

Journal: Protein expression and purification 20090801

Title: Oleoylethanolamide, a natural ligand for PPAR-alpha, inhibits insulin receptor signalling in HTC rat hepatoma cells.

Journal: Biochimica et biophysica acta 20090801

Title: Vaccinia-induced epidermal growth factor receptor-MEK signalling and the anti-apoptotic protein F1L synergize to suppress cell death during infection.

Journal: Cellular microbiology 20090801

Title: The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast cancer invasion and metastasis.

Journal: Traffic (Copenhagen, Denmark) 20090801

Title: Systems-wide analysis of a phosphatase knock-down by quantitative proteomics and phosphoproteomics.

Journal: Molecular & cellular proteomics : MCP 20090801

Title: Early effects of high glucose in retinal tissue cultures Renin-Angiotensin system-dependent and -independent signaling.

Journal: Neurobiology of disease 20090801

Title: Defects in cell spreading and ERK1/2 activation in fibroblasts with lamin A/C mutations.

Journal: Biochimica et biophysica acta 20090801

Title: Differential effects of EGFR ligands on endocytic sorting of the receptor.

Journal: Traffic (Copenhagen, Denmark) 20090801

Title: An extensive survey of tyrosine phosphorylation revealing new sites in human mammary epithelial cells.

Journal: Journal of proteome research 20090801

Title: Fibroblast growth factor receptor-1 phosphorylation requirement for cardiomyocyte differentiation in murine embryonic stem cells.

Journal: Journal of cellular and molecular medicine 20090801

Title: Bidirectional regulation of insulin receptor autophosphorylation and kinase activity by peroxynitrite.

Journal: Archives of biochemistry and biophysics 20090801

Title: pY-STAT3 and p53 expression predict outcome for poor prognosis diffuse large B-cell lymphoma treated with high dose chemotherapy and autologous stem cell transplantation.

Journal: Leukemia & lymphoma 20090801

Title: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle.

Journal: The FEBS journal 20090801

Title: Phosphorylation of the SSBP2 and ABL proteins by the ZNF198-FGFR1 fusion kinase seen in atypical myeloproliferative disorders as revealed by phosphopeptide-specific MS.

Journal: Proteomics 20090801

Title: Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination.

Journal: Molecular cancer research : MCR 20090801

Title: Cadherin-cadherin engagement promotes cell survival via Rac1/Cdc42 and signal transducer and activator of transcription-3.

Journal: Molecular cancer research : MCR 20090801

Title: The Drosophila SH2B family adaptor Lnk acts in parallel to chico in the insulin signaling pathway.

Journal: PLoS genetics 20090801

Title: Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.

Journal: PLoS pathogens 20090801

Title: [Detection of phosphotyrosine in chronic myeloid leukemia cells with PY20 antibody and its clinical applications].

Journal: Zhongguo shi yan xue ye xue za zhi 20090801

Title: Hierarchical modeling of activation mechanisms in the ABL and EGFR kinase domains: thermodynamic and mechanistic catalysts of kinase activation by cancer mutations.

Journal: PLoS computational biology 20090801

Title: Identification of pY19-caveolin-2 as a positive regulator of insulin-stimulated actin cytoskeleton-dependent mitogenesis.

Journal: Journal of cellular and molecular medicine 20090801

Title: Protein-tyrosine phosphatase-alpha and Src functionally link focal adhesions to the endoplasmic reticulum to mediate interleukin-1-induced Ca2+ signaling.

Journal: The Journal of biological chemistry 20090731

Title: Regulation of the innate immune response by threonine-phosphatase of Eyes absent.

Journal: Nature 20090723

Title: In vitro enzymatic characterization of near full length EGFR in activated and inhibited states.

Journal: Biochemistry 20090721

Title: Selective detection of phosphotyrosine in the presence of various phosphate-containing biomolecules with the aid of a terbium(III) complex.

Journal: Chembiochem : a European journal of chemical biology 20090720

Title: Dephosphorylation of major sperm protein (MSP) fiber protein 3 by protein phosphatase 2A during cell body retraction in the MSP-based amoeboid motility of Ascaris sperm.

Journal: Molecular biology of the cell 20090715

Title: Regulation of process retraction and cell migration by EphA3 is mediated by the adaptor protein Nck1.

Journal: Biochemistry 20090714

Title: Dasatinib synergizes with doxorubicin to block growth, migration, and invasion of breast cancer cells.

Journal: British journal of cancer 20090707

Title: Quantitative immunohistochemical expression of c Kit in breast carcinomas is predictive of patients' outcome.

Journal: British journal of cancer 20090707

Title: Prolectin, a glycan-binding receptor on dividing B cells in germinal centers.

Journal: The Journal of biological chemistry 20090703

Title: Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/TCF-mediated transcription.

Journal: The Journal of biological chemistry 20090703

Title: The importance of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kilodaltons sterile-alpha motif domain in thymic selection and T-cell activation.

Journal: Blood 20090702

Title: Protein kinase C-Fyn kinase cascade mediates the oleic acid-induced disassembly of neonatal rat cardiomyocyte adherens junctions.

Journal: The international journal of biochemistry & cell biology 20090701

Title: Signal transduction by CD58: the transmembrane isoform transmits signals outside lipid rafts independently of the GPI-anchored isoform.

Journal: Cellular signalling 20090701

Title: Reciprocal regulation of Abl and receptor tyrosine kinases.

Journal: Cellular signalling 20090701

Title: Phosphorylation of the activation loop tyrosines is required for sustained Syk signaling and growth factor-independent B-cell proliferation.

Journal: Cellular signalling 20090701

Title: The phosphoproteome of bloodstream form Trypanosoma brucei, causative agent of African sleeping sickness.

Journal: Molecular & cellular proteomics : MCP 20090701

Title: Purple acid phosphatase-like sequences in prokaryotic genomes and the characterization of an atypical purple alkaline phosphatase from Burkholderia cenocepacia J2315.

Journal: Gene 20090701

Title: Regulation of colonic apical potassium (BK) channels by cAMP and somatostatin.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20090701

Title: Anthrax infection inhibits the AKT signaling involved in the E-cadherin-mediated adhesion of lung epithelial cells.

Journal: FEMS immunology and medical microbiology 20090701

Title: Caveolin-2 regulation of STAT3 transcriptional activation in response to insulin.

Journal: Biochimica et biophysica acta 20090701

Title: Fibrinogen binding to ICAM-1 promotes EGFR-dependent mucin production in human airway epithelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20090701

Title: Quenched ligand-directed tosylate reagents for one-step construction of turn-on fluorescent biosensors.

Journal: Journal of the American Chemical Society 20090701

Title: Setaria cervi dual specific phosphatase: characterization and its effect on eosinophil degranulation.

Journal: Parasitology 20090701

Title: Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease.

Journal: Cancer research 20090701

Title: Chemical genetics reveals bacterial and host cell functions critical for type IV effector translocation by Legionella pneumophila.

Journal: PLoS pathogens 20090701

Title: Response prediction to a multitargeted kinase inhibitor in cancer cell lines and xenograft tumors using high-content tyrosine peptide arrays with a kinetic readout.

Journal: Molecular cancer therapeutics 20090701

Title: Spectroscopic characterization of the SH2- and active site-directed peptide sequences of a bivalent Src kinase inhibitor.

Journal: Applied spectroscopy 20090701

Title: Large-scale proteomic analysis of tyrosine-phosphorylation induced by T-cell receptor or B-cell receptor activation reveals new signaling pathways.

Journal: Proteomics 20090701

Title: The Y's that bind: negative regulators of Src family kinase activity in platelets.

Journal: Journal of thrombosis and haemostasis : JTH 20090701

Title: Numb-mediated neurite outgrowth is isoform-dependent, and requires activation of voltage-dependent calcium channels.

Journal: Neuroscience 20090630

Title: Role of the IRS-1 and/or -2 in the pathogenesis of insulin resistance in Dahl salt-sensitive (S) rats.

Journal: Heart international 20090630

Title: Ligand switching in cell-permeable peptides: manipulation of the alpha-integrin signature motif.

Journal: ACS chemical biology 20090619

Title: Identification of a novel negative regulator of activin/nodal signaling in mesendodermal formation of Xenopus embryos.

Journal: The Journal of biological chemistry 20090619

Title: Sennoside B inhibits PDGF receptor signaling and cell proliferation induced by PDGF-BB in human osteosarcoma cells.

Journal: Life sciences 20090619

Title: Phosphoproteomic analysis of Syk kinase signaling in human cancer cells reveals its role in cell-cell adhesion.

Journal: Oncogene 20090618

Title: Evidence for convergent evolution in the signaling properties of a choanoflagellate tyrosine kinase.

Journal: Biochemistry 20090616

Title: Oxidative stress induces lipid-raft-mediated activation of Src homology 2 domain-containing protein-tyrosine phosphatase 2 in astrocytes.

Journal: Free radical biology & medicine 20090615

Title: Anaplastic lymphoma kinase: signalling in development and disease.

Journal: The Biochemical journal 20090615

Title: Steel factor enhances supraoptimal antigen-induced IL-6 production from mast cells via activation of protein kinase C-beta.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20090615

Title: PTPRR protein tyrosine phosphatase isoforms and locomotion of vesicles and mice.

Journal: Cerebellum (London, England) 20090601

Title: Angiotensin-(1-7) activates a tyrosine phosphatase and inhibits glucose-induced signalling in proximal tubular cells.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090601

Title: Connective tissue growth factor(CCN2), a pathogenic factor in diabetic nephropathy. What does it do? How does it do it?

Journal: Journal of cell communication and signaling 20090601

Title: Glycogen synthase kinase-3 promotes the synergistic action of interferon-gamma on lipopolysaccharide-induced IL-6 production in RAW264.7 cells.

Journal: Cellular signalling 20090601

Title: Inhibition of insulin-stimulated hydrogen peroxide production prevents stimulation of sodium transport in A6 cell monolayers.

Journal: American journal of physiology. Renal physiology 20090601

Title: Inhibition of Src activity decreases tyrosine phosphorylation of occludin in brain capillaries and attenuates increase in permeability of the blood-brain barrier after transient focal cerebral ischemia.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090601

Title: Gas-phase intramolecular phosphate shift in phosphotyrosine-containing peptide monoanions.

Journal: Analytical chemistry 20090601

Title: Negative ion fragmentations of deprotonated peptides containing post-translational modifications. An unusual cyclisation/rearrangement involving phosphotyrosine; a joint experimental and theoretical study.

Journal: Rapid communications in mass spectrometry : RCM 20090601

Title: Revisiting histidine-dependent acid phosphatases: a distinct group of tyrosine phosphatases.

Journal: Trends in biochemical sciences 20090601

Title: [In vitro capacitation].

Journal: Gynecologie, obstetrique & fertilite 20090601

Title: Dok-4 is a novel negative regulator of T cell activation.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20090601

Title: Cross-talk between TLR4 and FcgammaReceptorIII (CD16) pathways.

Journal: PLoS pathogens 20090601

Title: Direct binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesis.

Journal: PLoS biology 20090601

Title: A sensitive magnetic bead method for the detection and identification of tyrosine phosphorylation in proteins by MALDI-TOF/TOF MS.

Journal: Proteomics 20090601

Title: Connecting quorum sensing, c-di-GMP, pel polysaccharide, and biofilm formation in Pseudomonas aeruginosa through tyrosine phosphatase TpbA (PA3885).

Journal: PLoS pathogens 20090601

Title: P66Shc signals to age.

Journal: Aging 20090601

Title: The structure of an interdomain complex that regulates talin activity.

Journal: The Journal of biological chemistry 20090529

Title: Density-enhanced phosphatase 1 regulates phosphorylation of tight junction proteins and enhances barrier function of epithelial cells.

Journal: The Journal of biological chemistry 20090529

Title: Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria.

Journal: The Journal of biological chemistry 20090529

Title: Phospholipase D-mediated activation of IQGAP1 through Rac1 regulates hyperoxia-induced p47phox translocation and reactive oxygen species generation in lung endothelial cells.

Journal: The Journal of biological chemistry 20090529

Title: Structure and in vivo requirement of the yeast Spt6 SH2 domain.

Journal: Journal of molecular biology 20090529

Title: Cucurbitane-type triterpenoids from the stems of Cucumis melo.

Journal: Journal of natural products 20090522

Title: Src supports UDP-glucuronosyltransferase-2B7 detoxification of catechol estrogens associated with breast cancer.

Journal: Biochemical and biophysical research communications 20090515

Title: Discovery of thioether-bridged cyclic pentapeptides binding to Grb2-SH2 domain with high affinity.

Journal: Bioorganic & medicinal chemistry letters 20090515

Title: The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis.

Journal: Blood 20090514

Title: FAK mediates the inhibition of glioma cell migration by truncated 24 kDa FGF-2.

Journal: Biochemical and biophysical research communications 20090508

Title: Purinergic regulation of vascular endothelial growth factor signaling in angiogenesis.

Journal: British journal of cancer 20090505

Title: Regulation of macrophage nitric oxide production by the protein tyrosine phosphatase Src homology 2 domain phosphotyrosine phosphatase 1 (SHP-1).

Journal: Immunology 20090501

Title: Enhanced clonogenic survival induced by protein tyrosine phosphatase (PTP) inhibition after Cr(VI) exposure is mediated by c-Raf and Ras activity.

Journal: Cellular signalling 20090501

Title: In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation.

Journal: DNA repair 20090501

Title: 14-3-3:Shc scaffolds integrate phosphoserine and phosphotyrosine signaling to regulate phosphatidylinositol 3-kinase activation and cell survival.

Journal: The Journal of biological chemistry 20090501

Title: Interaction of Mint2 with TrkA is involved in regulation of nerve growth factor-induced neurite outgrowth.

Journal: The Journal of biological chemistry 20090501

Title: Targeted disruption of ROCK1 causes insulin resistance in vivo.

Journal: The Journal of biological chemistry 20090501

Title: Systematic LC-MS analysis of labile post-translational modifications in complex mixtures.

Journal: Journal of proteome research 20090501

Title: Bacteria-induced uroplakin signaling mediates bladder response to infection.

Journal: PLoS pathogens 20090501

Title: A structure-based approach for detection of thiol oxidoreductases and their catalytic redox-active cysteine residues.

Journal: PLoS computational biology 20090501

Title: Peroxynitrite signaling in human erythrocytes: synergistic role of hemoglobin oxidation and band 3 tyrosine phosphorylation.

Journal: Archives of biochemistry and biophysics 20090415

Title: Visualizing immune system complexity.

Journal: Science signaling 20090414

Title: Presenilin 1 affects focal adhesion site formation and cell force generation via c-Src transcriptional and posttranslational regulation.

Journal: The Journal of biological chemistry 20090410

Title: Annexin 2 has a dual role as regulator and effector of v-Src in cell transformation.

Journal: The Journal of biological chemistry 20090410

Title: Aggregation of membrane proteins by cytosolic cross-linkers: theory and simulation of the LAT-Grb2-SOS1 system.

Journal: Biophysical journal 20090408

Title: Inappropriate activation of cyclin-dependent kinases by the phosphatase Cdc25b results in premature mitotic entry and triggers a p53-dependent checkpoint.

Journal: The Journal of biological chemistry 20090403

Title: Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain.

Journal: Journal of molecular biology 20090403

Title: Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions.

Journal: Nature 20090402

Title: DNA repair: New tales of an old tail.

Journal: Nature 20090402

Title: Epidermal growth factor receptors: function modulation by phosphorylation and glycosylation interplay.

Journal: Molecular biology reports 20090401

Title: From immune response to cancer: a spot on the low molecular weight protein tyrosine phosphatase.

Journal: Cellular and molecular life sciences : CMLS 20090401

Title: Cloning, expression, purification and functional characterization of the oligomerization domain of Bcr-Abl oncoprotein fused to the cytoplasmic transduction peptide.

Journal: Protein expression and purification 20090401

Title: Identification and characterization of neuronal mitogen-activated protein kinase substrates using a specific phosphomotif antibody.

Journal: Molecular & cellular proteomics : MCP 20090401

Title: Phosphotyrosine-dependent in vitro reconstitution of recombinant LAT-nucleated multiprotein signalling complexes on liposomes.

Journal: Molecular membrane biology 20090401

Title: Beta-Cell hyperplasia induced by hepatic insulin resistance: role of a liver-pancreas endocrine axis through insulin receptor A isoform.

Journal: Diabetes 20090401

Title: The mixed-lineage kinase DLK undergoes Src-dependent tyrosine phosphorylation and activation in cells exposed to vanadate or platelet-derived growth factor (PDGF).

Journal: Cellular signalling 20090401

Title: Identification and specific localization of tyrosine-phosphorylated proteins in Trypanosoma brucei.

Journal: Eukaryotic cell 20090401

Title: Phosphorylation of the amino-terminal region of X11L regulates its interaction with APP.

Journal: Journal of neurochemistry 20090401

Title: Mitochondrial diacylglycerol initiates protein-kinase D1-mediated ROS signaling.

Journal: Journal of cell science 20090401

Title: Endocytosis of flotillin-1 and flotillin-2 is regulated by Fyn kinase.

Journal: Journal of cell science 20090401

Title: Kinome signaling through regulated protein-protein interactions in normal and cancer cells.

Journal: Current opinion in cell biology 20090401

Title: Tyrosine phosphoproteome of hamster spermatozoa: role of glycerol-3-phosphate dehydrogenase 2 in sperm capacitation.

Journal: Proteomics 20090401

Title: Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling.

Journal: PLoS computational biology 20090401

Title: Role of H(2)O(2)-activated TRPM2 calcium channel in oxidant-induced endothelial injury.

Journal: Thrombosis and haemostasis 20090401

Title: A bipolar clamp mechanism for activation of Jak-family protein tyrosine kinases.

Journal: PLoS computational biology 20090401

Title: Current Screens Based on the AlphaScreen Technology for Deciphering Cell Signalling Pathways.

Journal: Current genomics 20090401

Title: Association of constitutively activated hepatocyte growth factor receptor (Met) with resistance to a dual EGFR/Her2 inhibitor in non-small-cell lung cancer cells.

Journal: British journal of cancer 20090324

Title: Time-dependent effects of imatinib in human leukaemia cells: a kinetic NMR-profiling study.

Journal: British journal of cancer 20090324

Title: Radiosensitisation of U87MG brain tumours by anti-epidermal growth factor receptor monoclonal antibodies.

Journal: British journal of cancer 20090324

Title: The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL.

Journal: Blood 20090319

Title: The Salmonella effector SptP dephosphorylates host AAA+ ATPase VCP to promote development of its intracellular replicative niche.

Journal: Cell host & microbe 20090319

Title: Molecular dynamics simulations reveal that Tyr-317 phosphorylation reduces Shc binding affinity for phosphotyrosyl residues of epidermal growth factor receptor.

Journal: Biophysical journal 20090318

Title: Automated metal-free multiple-column nanoLC for improved phosphopeptide analysis sensitivity and throughput.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090315

Title: Dual-specificity phosphatases: critical regulators with diverse cellular targets.

Journal: The Biochemical journal 20090315

Title: T-independent antibody responses to T-dependent antigens: a novel follicular dendritic cell-dependent activity.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20090315

Title: S100A13-C2A binary complex structure-a key component in the acidic fibroblast growth factor for the non-classical pathway.

Journal: Biochemical and biophysical research communications 20090313

Title: Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation.

Journal: Structure (London, England : 1993) 20090311

Title: Growth factors outside of the platelet-derived growth factor (PDGF) family employ reactive oxygen species/Src family kinases to activate PDGF receptor alpha and thereby promote proliferation and survival of cells.

Journal: The Journal of biological chemistry 20090306

Title: Protein and lipid kinase inhibitors as targeted anticancer agents of the Ras/Raf/MEK and PI3K/PKB pathways.

Journal: Purinergic signalling 20090301

Title: Proteomics study of medullary thyroid carcinomas expressing RET germ-line mutations: identification of new signaling elements.

Journal: Molecular carcinogenesis 20090301

Title: Binding specificity of SH2 domains: insight from free energy simulations.

Journal: Proteins 20090301

Title: The phosphotyrosine interactome of the insulin receptor family and its substrates IRS-1 and IRS-2.

Journal: Molecular & cellular proteomics : MCP 20090301

Title: Leptin but not ciliary neurotrophic factor (CNTF) induces phosphotyrosine phosphatase-1B expression in human neuronal cells (SH-SY5Y): putative explanation of CNTF efficacy in leptin-resistant state.

Journal: Endocrinology 20090301

Title: Diabetes reduces autophosphorylation of retinal insulin receptor and increases protein-tyrosine phosphatase-1B activity.

Journal: Investigative ophthalmology & visual science 20090301

Title: A PPM-family protein phosphatase from the thermoacidophile Thermoplasma volcanium hydrolyzes protein-bound phosphotyrosine.

Journal: Extremophiles : life under extreme conditions 20090301

Title: Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress.

Journal: Diabetes 20090301

Title: The current state of proteomics in GI oncology.

Journal: Digestive diseases and sciences 20090301

Title: Two related cases of type A insulin resistance with compound heterozygous mutations of the insulin receptor gene.

Journal: Diabetes research and clinical practice 20090301

Title: Role of nonreceptor protein tyrosine kinases during phospholipase C-gamma 1-related uterine contractions in the rat.

Journal: Reproductive sciences (Thousand Oaks, Calif.) 20090301

Title: The beta-catenin axis integrates multiple signals downstream from RET/papillary thyroid carcinoma leading to cell proliferation.

Journal: Cancer research 20090301

Title: Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms.

Journal: Molecular bioSystems 20090301

Title: Molecular imaging of Bcr-Abl phosphokinase in a xenograft model.

Journal: Molecular cancer therapeutics 20090301

Title: The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T cell antigen receptor signaling.

Journal: PLoS pathogens 20090301

Title: Regulation of embryonic cell adhesion by the prion protein.

Journal: PLoS biology 20090301

Title: Regulation of focal adhesion turnover by ErbB signalling in invasive breast cancer cells.

Journal: British journal of cancer 20090224

Title: Neurotrophin receptor activation and expression in human postmortem brain: effect of suicide.

Journal: Biological psychiatry 20090215

Title: A HIF-1alpha-dependent autocrine feedback loop promotes survival of serum-deprived prostate cancer cells.

Journal: The Prostate 20090215

Title: Transcription factor TFII-I causes transcriptional upregulation of GRP78 synthesis in prostate cancer cells.

Journal: Journal of cellular biochemistry 20090215

Title: Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation.

Journal: The Journal of biological chemistry 20090213

Title: Cross-linking of FcepsilonRI causes Ca2+ mobilization via a sphingosine kinase pathway in a clathrin-dependent manner.

Journal: Cell calcium 20090201

Title: Temporal perturbation of tyrosine phosphoproteome dynamics reveals the system-wide regulatory networks.

Journal: Molecular & cellular proteomics : MCP 20090201

Title: Grp94 is Tyr-phosphorylated by Fyn in the lumen of the endoplasmic reticulum and translocates to Golgi in differentiating myoblasts.

Journal: Biochimica et biophysica acta 20090201

Title: Structural insights into the inhibited states of the Mer receptor tyrosine kinase.

Journal: Journal of structural biology 20090201

Title: Role of initial protein phosphorylation events and localized release-activated calcium influx in B cell antigen receptor signaling.

Journal: Journal of leukocyte biology 20090201

Title: PKCdelta-dependent functional switch of rpS3 between translation and DNA repair.

Journal: Biochimica et biophysica acta 20090201

Title: Signal transducer and activator of transcription 5 tyrosine phosphorylation for the diagnosis and monitoring of patients with severe combined immunodeficiency.

Journal: The Journal of allergy and clinical immunology 20090201

Title: Differential ligand binding to a human cytomegalovirus chemokine receptor determines cell type-specific motility.

Journal: PLoS pathogens 20090201

Title: Src kinase Hck association with the WASp and mDia1 cytoskeletal regulators promotes chemoattractant-induced Hck membrane targeting and activation in neutrophils.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20090201

Title: [Expression and kinetic analysis of catalytic domain of protein tyrosine phosphatases SHP-1/SHP-2].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20090201

Title: PKD2 interacts with Lck and regulates NFAT activity in T cells.

Journal: BMB reports 20090131

Title: Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin.

Journal: British journal of cancer 20090127

Title: Restriction of Src activity by Cullin-5.

Journal: Current biology : CB 20090127

Title: Large-scale structural analysis of the classical human protein tyrosine phosphatome.

Journal: Cell 20090123

Title: The junctional integrity of epithelial cells is modulated by Pseudomonas aeruginosa quorum sensing molecule through phosphorylation-dependent mechanisms.

Journal: Experimental cell research 20090115

Title: Glutamate acting on N-methyl-D-aspartate receptors attenuates insulin-like growth factor-1 receptor tyrosine phosphorylation and its survival signaling properties in rat hippocampal neurons.

Journal: The Journal of biological chemistry 20090109

Title: Involvement of Src tyrosine kinases (SFKs) and of focal adhesion kinase (FAK) in the injurious mechanism in rat primary neuronal cultures exposed to chemical ischemia.

Journal: Journal of molecular neuroscience : MN 20090101

Title: ERK1/2 mediate wounding- and G-protein-coupled receptor ligands-induced EGFR activation via regulating ADAM17 and HB-EGF shedding.

Journal: Investigative ophthalmology & visual science 20090101

Title: Tyrosine phosphorylation of insulin receptor substrates during ischemia/reperfusion-induced apoptosis in rat liver.

Journal: Langenbeck's archives of surgery 20090101

Title: Flow cytometric assay of phosphotyrosine levels in Bcr-Abl-positive chronic myelogenous leukemias: a potential prognostic marker.

Journal: Annals of hematology 20090101

Title: Enhancement of sperm-zona pellucida (ZP) binding capacity by activation of protein kinase A and C pathways in certain infertile men with defective sperm-ZP binding.

Journal: Human reproduction (Oxford, England) 20090101

Title: Peroxynitrite-dependent activation of protein phosphatase type 2A mediates microvascular endothelial barrier dysfunction.

Journal: Cardiovascular research 20090101

Title: Giardia lamblia: Characterization of ecto-phosphatase activities.

Journal: Experimental parasitology 20090101

Title: APPL1: role in adiponectin signaling and beyond.

Journal: American journal of physiology. Endocrinology and metabolism 20090101

Title: Dissociation of tau toxicity and phosphorylation: role of GSK-3beta, MARK and Cdk5 in a Drosophila model.

Journal: Human molecular genetics 20090101

Title: Positively regulated glycerol/G3P-dependent Bacillus subtilis gene expression system based on anti-termination.

Journal: Journal of molecular microbiology and biotechnology 20090101

Title: The counteradhesive proteins, thrombospondin 1 and SPARC/osteonectin, open the tyrosine phosphorylation-responsive paracellular pathway in pulmonary vascular endothelia.

Journal: Microvascular research 20090101

Title: Hypoxia decreases insulin signaling pathways in adipocytes.

Journal: Diabetes 20090101

Title: Detection of homo- or hetero-association of Doks by fluorescence resonance energy transfer in living cells.

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20090101

Title: Antiplatelet activity of beta-carboline alkaloids from Perganum harmala: a possible mechanism through inhibiting PLCgamma2 phosphorylation.

Journal: Vascular pharmacology 20090101

Title: WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity.

Journal: Nature 20090101

Title: Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance.

Journal: BMC systems biology 20090101

Title: Beta amyloid oligomers and fibrils stimulate differential activation of primary microglia.

Journal: Journal of neuroinflammation 20090101

Title: Norrin attenuates protease-mediated death of transformed retinal ganglion cells.

Journal: Molecular vision 20090101

Title: Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion.

Journal: BMC cancer 20090101

Title: Identification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assay.

Journal: Molecular cancer therapeutics 20090101

Title: Linear combinations of docking affinities explain quantitative differences in RTK signaling.

Journal: Molecular systems biology 20090101

Title: The IpaC carboxyterminal effector domain mediates Src-dependent actin polymerization during Shigella invasion of epithelial cells.

Journal: PLoS pathogens 20090101

Title: Brain-derived neurotrophic factor modulation of Kv1.3 channel is disregulated by adaptor proteins Grb10 and nShc.

Journal: BMC neuroscience 20090101

Title: Preparation and Characterization of a Polyclonal Antibody against Brominated Protein.

Journal: Journal of clinical biochemistry and nutrition 20090101

Title: Nck adapter proteins: functional versatility in T cells.

Journal: Cell communication and signaling : CCS 20090101

Title: Olive tree wood phenolic compounds with human platelet antiaggregant properties.

Journal: Blood cells, molecules & diseases 20090101

Title: The effect of the dual Src/Abl kinase inhibitor AZD0530 on Philadelphia positive leukaemia cell lines.

Journal: BMC cancer 20090101

Title: Phosphorylation of a tyrosine in the amyloid-beta protein precursor intracellular domain inhibits Fe65 binding and signaling.

Journal: Journal of Alzheimer's disease : JAD 20090101

Title: Characterization of new substrates targeted by Yersinia tyrosine phosphatase YopH.

Journal: PloS one 20090101

Title: Sequence-based feature prediction and annotation of proteins.

Journal: Genome biology 20090101

Title: Antigen receptor signaling in the rheumatic diseases.

Journal: Arthritis research & therapy 20090101

Title: Interaction between O-GlcNAc modification and tyrosine phosphorylation of prohibitin: implication for a novel binary switch.

Journal: PloS one 20090101

Title: Taurine and guanidinoethanesulfonic acid (GES) differentially affects the expression and phosphorylation of cellular proteins in C6 glial cells.

Journal: Advances in experimental medicine and biology 20090101

Title: Identification of oxidative stress-induced tyrosine phosphorylated proteins by immunoprecipitation and mass spectrometry.

Journal: Methods in molecular biology (Clifton, N.J.) 20090101

Title: Use of stable isotope labeling by amino acids in cell culture (SILAC) for phosphotyrosine protein identification and quantitation.

Journal: Methods in molecular biology (Clifton, N.J.) 20090101

Title: SH2 domain binding to phosphopeptide ligands: potential for drug targeting.

Journal: Frontiers in bioscience (Landmark edition) 20090101

Title: Ser/Thr/Tyr protein phosphorylation in the archaeon Halobacterium salinarum--a representative of the third domain of life.

Journal: PloS one 20090101

Title: Chemical probes that competitively and selectively inhibit Stat3 activation.

Journal: PloS one 20090101

Title: Early cellular signaling responses to axonal injury.

Journal: Cell communication and signaling : CCS 20090101

Title: A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase.

Journal: PloS one 20090101

Title: Impact of anti-inflammatory agents on the gene expression profile of stimulated human neutrophils: unraveling endogenous resolution pathways.

Journal: PloS one 20090101

Title: The Drosophila cell adhesion molecule Neuroglian regulates Lissencephaly-1 localisation in circulating immunosurveillance cells.

Journal: BMC immunology 20090101

Title: Proteomic analysis of phosphoproteins sensitive to a phosphatidylinositol 3-kinase inhibitor, ZSTK474, by using SELDI-TOF MS.

Journal: Proteome science 20090101

Title: A DNA sequence directed mutual transcription regulation of HSF1 and NFIX involves novel heat sensitive protein interactions.

Journal: PloS one 20090101

Title: HD-PTP is a catalytically inactive tyrosine phosphatase due to a conserved divergence in its phosphatase domain.

Journal: PloS one 20090101

Title: FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4.

Journal: PloS one 20090101

Title: Inflammation and tumor progression: a lesson from TNF-alpha-dependent FAK signaling in cholangiocarcinoma.

Journal: Methods in molecular biology (Clifton, N.J.) 20090101

Title: Systems pharmacology and genome medicine: a future perspective.

Journal: Genome medicine 20090101

Title: Systems-level interactions between insulin-EGF networks amplify mitogenic signaling.

Journal: Molecular systems biology 20090101

Title: Rapid assessment of the effect of ciprofloxacin on chromosomal DNA from Escherichia coli using an in situ DNA fragmentation assay.

Journal: BMC microbiology 20090101

Title: Tumoral prostate shows different expression pattern of somatostatin receptor 2 (SSTR2) and phosphotyrosine phosphatase SHP-1 (PTPN6) according to tumor progression.

Journal: Advances in urology 20090101

Title: Analysis of the functional role of Toll-like receptor-4 tyrosine phosphorylation.

Journal: Methods in molecular biology (Clifton, N.J.) 20090101

Title: Unc119 protects from Shigella infection by inhibiting the Abl family kinases.

Journal: PloS one 20090101

Title: Activity-based protein profiling of protein tyrosine phosphatases.

Journal: Methods in molecular biology (Clifton, N.J.) 20090101

Title: Modulation of bovine sperm signalling pathways: correlation between intracellular parameters and sperm capacitation and acrosome exocytosis.

Journal: Reproduction, fertility, and development 20090101

Title: Cryopreservation affects bovine sperm intracellular parameters associated with capacitation and acrosome exocytosis.

Journal: Reproduction, fertility, and development 20090101

Title: The calcium-sensing receptor regulates parathyroid hormone gene expression in transfected HEK293 cells.

Journal: BMC biology 20090101

Title: Indirect recruitment of a CD40 signaling pathway in dendritic cells by B7-DC cross-linking antibody modulates T cell functions.

Journal: PloS one 20090101

Title: Src, PKCalpha, and PKCdelta are required for alphavbeta3 integrin-mediated metastatic melanoma invasion.

Journal: Cell communication and signaling : CCS 20090101

Title: Distinct phosphorylation requirements regulate cortactin activation by TirEPEC and its binding to N-WASP.

Journal: Cell communication and signaling : CCS 20090101

Title: Interface analysis of the complex between ERK2 and PTP-SL.

Journal: PloS one 20090101

Title: Interplay between the heterotrimeric G-protein subunits Galphaq and Galphai2 sets the threshold for chemotaxis and TCR activation.

Journal: BMC immunology 20090101

Title: Crk and CrkL adaptor proteins: networks for physiological and pathological signaling.

Journal: Cell communication and signaling : CCS 20090101

Title: Selective enrichment in phosphopeptides for the identification of phosphorylated mitochondrial proteins.

Journal: Methods in enzymology 20090101

Title: Distinguishing mitochondrial inner membrane orientation of dual specific phosphatase 18 and 21.

Journal: Methods in enzymology 20090101

Title: Revised Mimivirus major capsid protein sequence reveals intron-containing gene structure and extra domain.

Journal: BMC molecular biology 20090101

Title: MP470, a novel receptor tyrosine kinase inhibitor, in combination with Erlotinib inhibits the HER family/PI3K/Akt pathway and tumor growth in prostate cancer.

Journal: BMC cancer 20090101

Title: The -271 G>A polymorphism of kinase insert domain-containing receptor gene regulates its transcription level in patients with non-small cell lung cancer.

Journal: BMC cancer 20090101

Title: Helicobacter pylori induces cancer cell motility independent of the c-Met receptor.

Journal: Journal of carcinogenesis 20090101

Title: Avicin D: a protein reactive plant isoprenoid dephosphorylates Stat 3 by regulating both kinase and phosphatase activities.

Journal: PloS one 20090101

Title: Deleted in liver cancer 1 (DLC1) utilizes a novel binding site for Tensin2 PTB domain interaction and is required for tumor-suppressive function.

Journal: PloS one 20090101

Title: Replication of porcine circoviruses.

Journal: Virology journal 20090101

Title: Erythropoietin down-regulates stem cell factor receptor (Kit) expression in the leukemic proerythroblast: role of Lyn kinase.

Journal: PloS one 20090101

Title: Somatostatin and opioid receptors do not regulate proliferation or apoptosis of the human multiple myeloma U266 cells.

Journal: Journal of experimental & clinical cancer research : CR 20090101

Title: Analysis of DNA relaxation and cleavage activities of recombinant Mycobacterium tuberculosis DNA topoisomerase I from a new expression and purification protocol.

Journal: BMC biochemistry 20090101

Title: Fluorine-18 labeling of phosphopeptides: a potential approach for the evaluation of phosphopeptide metabolism in vivo.

Journal: Biopolymers 20090101

Title: Molecular characterization of lung dysplasia induced by c-Raf-1.

Journal: PloS one 20090101

Title: Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention.

Journal: BMC cancer 20090101

Title: Expression and function of the insulin receptor substrate proteins in cancer.

Journal: Cell communication and signaling : CCS 20090101

Title: Rapid insulin-dependent endocytosis of the insulin receptor by caveolae in primary adipocytes.

Journal: PloS one 20090101

Title: Disassembly of shank and homer synaptic clusters is driven by soluble beta-amyloid(1-40) through divergent NMDAR-dependent signalling pathways.

Journal: PloS one 20090101

Title: ERK2, but not ERK1, mediates acquired and 'de novo' resistance to imatinib mesylate: implication for CML therapy.

Journal: PloS one 20090101

Title: Structure-function analysis of nucleolin and ErbB receptors interactions.

Journal: PloS one 20090101

Title: Regulation of the physiological function and metabolism of AbetaPP by AbetaPP binding proteins.

Journal: Journal of Alzheimer's disease : JAD 20090101

Title: Yersinia outer protein YopE affects the actin cytoskeleton in Dictyostelium discoideum through targeting of multiple Rho family GTPases.

Journal: BMC microbiology 20090101

Title: The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains.

Journal: Molecular neurodegeneration 20090101

Title: Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein.

Journal: BMC cell biology 20090101

Title: PPAR-γ agonists and their effects on IGF-I receptor signaling: Implications for cancer.

Journal: PPAR research 20090101

Title: Identification of pediatric septic shock subclasses based on genome-wide expression profiling.

Journal: BMC medicine 20090101

Title: Structural models of human eEF1A1 and eEF1A2 reveal two distinct surface clusters of sequence variation and potential differences in phosphorylation.

Journal: PloS one 20090101

Title: Cytosolic SYT/SS18 isoforms are actin-associated proteins that function in matrix-specific adhesion.

Journal: PloS one 20090101

Title: Gonadotropin-releasing hormone (GnRH)-I and GnRH-II induce cell growth inhibition in human endometrial cancer cells: involvement of integrin beta3 and focal adhesion kinase.

Journal: Reproductive biology and endocrinology : RB&E 20090101

Title: Vav links the T cell antigen receptor to the actin cytoskeleton and T cell activation independently of intrinsic Guanine nucleotide exchange activity.

Journal: PloS one 20090101

Title: Are small GTPases signal hubs in sugar-mediated induction of fructan biosynthesis?

Journal: PloS one 20090101

Title: Tyrosine phosphorylation in immune cells: direct and indirect effects on toll-like receptor-induced proinflammatory cytokine production.

Journal: Critical reviews in immunology 20090101

Title: Fibronectin-replating experiment: procedure and analysis.

Journal: Folia biologica 20090101

Title: Imatinib induces apoptosis by inhibiting PDGF- but not insulin-induced PI 3-kinase/Akt survival signaling in RGC-5 retinal ganglion cells.

Journal: Molecular vision 20090101

Title: Prolactin signaling through the short isoform of the mouse prolactin receptor regulates DNA binding of specific transcription factors, often with opposite effects in different reproductive issues.

Journal: Reproductive biology and endocrinology : RB&E 20090101

Title: Current available therapies and future directions in the treatment of malignant gliomas.

Journal: Biologics : targets & therapy 20090101

Title: Maximum entropy reconstructions of dynamic signaling networks from quantitative proteomics data.

Journal: PloS one 20090101

Title: STAT5 regulation of BCL10 parallels constitutive NFkappaB activation in lymphoid tumor cells.

Journal: Molecular cancer 20090101

Title: Proteomic characterization of HIV-modulated membrane receptors, kinases and signaling proteins involved in novel angiogenic pathways.

Journal: Journal of translational medicine 20090101

Title: Talking to chromatin: post-translational modulation of polycomb group function.

Journal: Epigenetics & chromatin 20090101

Title: ApoE isoform-dependent changes in hippocampal synaptic function.

Journal: Molecular neurodegeneration 20090101

Title: Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis.

Journal: Journal of molecular signaling 20090101

Title: Function, regulation and pathological roles of the Gab/DOS docking proteins.

Journal: Cell communication and signaling : CCS 20090101

Title: LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation.

Journal: PloS one 20090101

Title: 2D proteome analysis initiates new insights on the Salmonella Typhimurium LuxS protein.

Journal: BMC microbiology 20090101

Title: PSSA-2, a membrane-spanning phosphoprotein of Trypanosoma brucei, is required for efficient maturation of infection.

Journal: PloS one 20090101

Title: Barrier-to-autointegration factor proteome reveals chromatin-regulatory partners.

Journal: PloS one 20090101

Title: High sequence homology between protein tyrosine acid phosphatase from boar seminal vesicles and human prostatic acid phosphatase.

Journal: Acta biochimica Polonica 20090101

Title: Gene expression profiling in cells with enhanced gamma-secretase activity.

Journal: PloS one 20090101

Title: VEGFR1 activity modulates myeloid cell infiltration in growing lung metastases but is not required for spontaneous metastasis formation.

Journal: PloS one 20090101

Title: SOCS2 influences LPS induced human monocyte-derived dendritic cell maturation.

Journal: PloS one 20090101

Title: Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT.

Journal: PloS one 20090101

Title: Locomotion guidance by extracellular matrix is adaptive and can be restored by a transient change in Ca2+ level.

Journal: PloS one 20090101

Title: Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region.

Journal: PloS one 20090101

Title: Tumor-shed PGE(2) impairs IL2Rgammac-signaling to inhibit CD4 T cell survival: regulation by theaflavins.

Journal: PloS one 20090101

Title: Eps15: a multifunctional adaptor protein regulating intracellular trafficking.

Journal: Cell communication and signaling : CCS 20090101

Title: A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice.

Journal: PloS one 20090101

Title: Empirical Bayes analysis of quantitative proteomics experiments.

Journal: PloS one 20090101

Title: Stretch activates human myometrium via ERK, caldesmon and focal adhesion signaling.

Journal: PloS one 20090101

Title: Identification of tyrosine-phosphorylated proteins associated with metastasis and functional analysis of FER in human hepatocellular carcinoma cells.

Journal: BMC cancer 20090101

Title: Molecular machines or pleiomorphic ensembles: signaling complexes revisited.

Journal: Journal of biology 20090101

Title: Partially-supervised protein subclass discovery with simultaneous annotation of functional residues.

Journal: BMC structural biology 20090101

Title: Rab11 helps maintain apical crumbs and adherens junctions in the Drosophila embryonic ectoderm.

Journal: PloS one 20090101

Title: multiplierz: an extensible API based desktop environment for proteomics data analysis.

Journal: BMC bioinformatics 20090101

Title: Hepatic gene expression profiling reveals protective responses in Atlantic salmon vaccinated against furunculosis.

Journal: BMC genomics 20090101

Title: Gas6 and the receptor tyrosine kinase Axl in clear cell renal cell carcinoma.

Journal: PloS one 20090101

Title: Fyn mediates leptin actions in the thymus of rodents.

Journal: PloS one 20090101

Title: A concerted kinase interplay identifies PPARgamma as a molecular target of ghrelin signaling in macrophages.

Journal: PloS one 20090101

Title: MALDI profiling of human lung cancer subtypes.

Journal: PloS one 20090101

Title: Azithromycin suppresses interleukin-12p40 expression in lipopolysaccharide and interferon-gamma stimulated macrophages.

Journal: International journal of biological sciences 20090101

Title: The presence of alpha-catenin in the VE-cadherin complex is required for efficient transendothelial migration of leukocytes.

Journal: International journal of biological sciences 20090101

Title: Impact of biospecimens handling on biomarker research in breast cancer.

Journal: BMC cancer 20090101

Title: Antiproliferative effect of exemestane in lung cancer cells.

Journal: Molecular cancer 20090101

Title: PRL-3 promotes the motility, invasion, and metastasis of LoVo colon cancer cells through PRL-3-integrin beta1-ERK1/2 and-MMP2 signaling.

Journal: Molecular cancer 20090101

Title: ERalpha increases expression and interacts with TERT in cataractous canine lens epithelial cells.

Journal: Molecular vision 20090101

Title: Fluorescence resonance energy transfer (FRET)-based subcellular visualization of pathogen-induced host receptor signaling.

Journal: BMC biology 20090101

Title: Insulin signaling pathways in a patient with insulin resistance of difficult management - a case report.

Journal: Diabetology & metabolic syndrome 20090101

Title: A predictive phosphorylation signature of lung cancer.

Journal: PloS one 20090101

Title: Aberrant trafficking of NSCLC-associated EGFR mutants through the endocytic recycling pathway promotes interaction with Src.

Journal: BMC cell biology 20090101

Title: Transcriptomic response of the mycoparasitic fungus Trichoderma atroviride to the presence of a fungal prey.

Journal: BMC genomics 20090101

Title: Sulfatides partition disabled-2 in response to platelet activation.

Journal: PloS one 20090101

Title: Expression-based network biology identifies alteration in key regulatory pathways of type 2 diabetes and associated risk/complications.

Journal: PloS one 20090101

Title: Molecular mechanism for human sperm chemotaxis mediated by progesterone.

Journal: PloS one 20090101

Title: Integrating complex genomic datasets and tumour cell sensitivity profiles to address a 'simple' question: which patients should get this drug?

Journal: BMC medicine 20090101

Title: Evidence that phosphatidylinositol 3-kinase is involved in sperm-induced tyrosine kinase signaling in Xenopus egg fertilization.

Journal: BMC developmental biology 20090101

Title: Soluble iron modulates iron oxide particle-induced inflammatory responses via prostaglandin E(2 )synthesis: In vitro and in vivo studies.

Journal: Particle and fibre toxicology 20090101

Title: Computational modeling of the EGFR network elucidates control mechanisms regulating signal dynamics.

Journal: BMC systems biology 20090101

Title: Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions.

Journal: Molecular systems biology 20090101

Title: An optimal protocol to analyze the rat spinal cord proteome.

Journal: Biomarker insights 20090101

Title: The function of cortactin in the clustering of acetylcholine receptors at the vertebrate neuromuscular junction.

Journal: PloS one 20090101

Title: Anomalous constitutive Src kinase activity promotes B lymphoma survival and growth.

Journal: Molecular cancer 20090101

Title: Identification of four novel phosphorylation sites in estrogen receptor alpha: impact on receptor-dependent gene expression and phosphorylation by protein kinase CK2.

Journal: BMC biochemistry 20090101

Title: Detection of R576 interleukin-4 receptor an allele gene, serum interleukin-4, and eosinophilic cationic protein in atopic dermatitis patients.

Journal: Indian journal of dermatology 20090101

Title: Determinants Present in the Receptor Carboxy Tail Are Responsible for Differences in Subtype-Specific Coupling of beta-Adrenergic Receptors to Phosphoinositide 3-Kinase.

Journal: International journal of cell biology 20090101

Title: Application of mass spectrometry-based proteomics for biomarker discovery in neurological disorders.

Journal: Annals of Indian Academy of Neurology 20090101

Title: TOM1L is involved in a novel signaling pathway important for the IL-2 production in Jurkat T cells stimulated by CD3/CD28 co-ligation.

Journal: Mediators of inflammation 20090101

Title: Multiple roles and therapeutic implications of Akt signaling in cancer.

Journal: OncoTargets and therapy 20090101

Title: Role of tyrosine phosphorylation in the antioxidant effects of the p75 neurotrophin receptor.

Journal: Oxidative medicine and cellular longevity 20090101

Title: Gene Expression and Serum Cytokine Profiling of Low Stage CLL Identify WNT/PCP, Flt-3L/Flt-3 and CXCL9/CXCR3 as Regulators of Cell Proliferation, Survival and Migration.

Journal: Human genomics and proteomics : HGP 20090101

Title: Caspase 8 promotes peripheral localization and activation of Rab5.

Journal: The Journal of biological chemistry 20081226

Title: Differential subcellular localization of insulin receptor substrates depends on C-terminal regions and importin beta.

Journal: Biochemical and biophysical research communications 20081219

Title: G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2.

Journal: The Journal of biological chemistry 20081219

Title: Remote changes in the dynamics of the phosphotyrosine-binding domain of insulin receptor substrate-1 induced by phosphopeptide binding.

Journal: Biochemistry 20081216

Title: CH/pi hydrogen bonds determine the selectivity of the Src homology 2 domain to tyrosine phosphotyrosyl peptides: an ab initio fragment molecular orbital study.

Journal: Journal of computational chemistry 20081201

Title: Structure, dynamics, and binding thermodynamics of the v-Src SH2 domain: implications for drug design.

Journal: Proteins 20081201

Title: E-cadherin core fucosylation regulates nuclear beta-catenin accumulation in lung cancer cells.

Journal: Glycoconjugate journal 20081201

Title: Parathyroid hormone-related protein (107-139) increases human osteoblastic cell survival by activation of vascular endothelial growth factor receptor-2.

Journal: Journal of cellular physiology 20081201

Title: Role of src-family kinases in hypoxic vasoconstriction of rat pulmonary artery.

Journal: Cardiovascular research 20081201

Title: Internalization of EGF receptor following lipid rafts disruption in keratinocytes is delayed and dependent on p38 MAPK activation.

Journal: Journal of cellular physiology 20081201

Title: A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion.

Journal: Blood 20081201

Title: A 32-kDa tyrosine-phosphorylated protein shows a protease-dependent increase in dead boar spermatozoa.

Journal: The Journal of reproduction and development 20081201

Title: Differential roles for the adapters Gads and LAT in platelet activation by GPVI and CLEC-2.

Journal: Journal of thrombosis and haemostasis : JTH 20081201

Title: Resistance to high-fat diet-induced obesity but exacerbated insulin resistance in mice overexpressing preadipocyte factor-1 (Pref-1): a new model of partial lipodystrophy.

Journal: Diabetes 20081201

Title: Expression of Fer testis (FerT) tyrosine kinase transcript variants and distribution sites of FerT during the development of the acrosome-acroplaxome-manchette complex in rat spermatids.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20081201

Title: Endothelial Src kinase regulates membrane recycling from the lateral border recycling compartment during leukocyte transendothelial migration.

Journal: European journal of immunology 20081201

Title: The fission yeast meiotic checkpoint kinase Mek1 regulates nuclear localization of Cdc25 by phosphorylation.

Journal: Cell cycle (Georgetown, Tex.) 20081201

Title: Specific blockade of VEGF and HER2 pathways results in greater growth inhibition of breast cancer xenografts that overexpress HER2.

Journal: Cell cycle (Georgetown, Tex.) 20081201

Title: Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction.

Journal: PLoS genetics 20081201

Title: Leishmania-induced IRAK-1 inactivation is mediated by SHP-1 interacting with an evolutionarily conserved KTIM motif.

Journal: PLoS neglected tropical diseases 20081201

Title: Role of stress fibers and focal adhesions as a mediator for mechano-signal transduction in endothelial cells in situ.

Journal: Vascular health and risk management 20081201

Title: Structural and functional characterization of the c-terminal domain of the ecdysteroid phosphate phosphatase from bombyx mori reveals a new enzymatic activity.

Journal: Biochemistry 20081118

Title: Negative regulation of TCR signaling by linker for activation of X cells via phosphotyrosine-dependent and -independent mechanisms.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20081115

Title: Genistein stimulates myocardial contractility in guinea pigs by different subcellular mechanisms.

Journal: European journal of pharmacology 20081112

Title: Inhibitory effect of HGF on invasiveness of aggressive MDA-MB231 breast carcinoma cells, and role of HDACs.

Journal: British journal of cancer 20081104

Title: Extracellular alkaline phosphatase is a sensitive marker for cellular stimulation and exocytosis in heterotroph cell cultures of Chenopodium rubrum.

Journal: Journal of plant physiology 20081101

Title: Insulin growth factor 1 receptor/PI3K/AKT survival pathway in outer segment membranes of rod photoreceptors.

Journal: Investigative ophthalmology & visual science 20081101

Title: Protein kinase CK2 catalyzes tyrosine phosphorylation in mammalian cells.

Journal: Cellular signalling 20081101

Title: Negative regulation of Jak2 by its auto-phosphorylation at tyrosine 913 via the Epo signaling pathway.

Journal: Cellular signalling 20081101

Title: JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin.

Journal: Cellular signalling 20081101

Title: Prostacyclin receptor-induced STAT3 phosphorylation in human erythroleukemia cells is mediated via Galpha(s) and Galpha(16) hybrid signaling.

Journal: Cellular signalling 20081101

Title: ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling.

Journal: Cellular signalling 20081101

Title: Protein tyrosine kinases and protein tyrosine phosphatases are involved in abscisic acid-dependent processes in Arabidopsis seeds and suspension cells.

Journal: Plant physiology 20081101

Title: The RACK1 signal anchor protein from Trypanosoma brucei associates with eukaryotic elongation factor 1A: a role for translational control in cytokinesis.

Journal: Molecular microbiology 20081101

Title: Hyaluronan-mediated leukocyte adhesion and dextran sulfate sodium-induced colitis are attenuated in the absence of signal transducer and activator of transcription 1.

Journal: The American journal of pathology 20081101

Title: Quantitative phosphoproteomics--an emerging key technology in signal-transduction research.

Journal: Proteomics 20081101

Title: Relationships between urinary inositol excretions and whole-body glucose tolerance and skeletal muscle insulin receptor phosphorylation.

Journal: Metabolism: clinical and experimental 20081101

Title: Multiplex detection and identification of proteins on a PVDF membrane blocked with a synthetic polymer-based reagent.

Journal: Electrophoresis 20081101

Title: A genetically hard-wired metabolic transcriptome in Plasmodium falciparum fails to mount protective responses to lethal antifolates.

Journal: PLoS pathogens 20081101

Title: Contribution of natural inhibitors to the understanding of the PI3K/PDK1/PKB pathway in the insulin-mediated intracellular signaling cascade.

Journal: International journal of molecular sciences 20081101

Title: Synthesis and utilization of chiral alpha-methylated alpha-amino acids with a carboxyalkyl side chain in the design of novel Grb2-SH2 peptide inhibitors free of phosphotyrosine.

Journal: Journal of medicinal chemistry 20081023

Title: Adaptor protein Lnk associates with Tyr(568) in c-Kit.

Journal: The Biochemical journal 20081015

Title: Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer.

Journal: British journal of cancer 20081007

Title: Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor alpha (WSX-1).

Journal: Annals of the rheumatic diseases 20081001

Title: Momordica charantia (bitter melon) reduces plasma apolipoprotein B-100 and increases hepatic insulin receptor substrate and phosphoinositide-3 kinase interactions.

Journal: The British journal of nutrition 20081001

Title: Sex-steroid hormones and EGF signalling in breast and prostate cancer cells: targeting the association of Src with steroid receptors.

Journal: Steroids 20081001

Title: Emerging roles for protein histidine phosphorylation in cellular signal transduction: lessons from the islet beta-cell.

Journal: Journal of cellular and molecular medicine 20081001

Title: Structural and functional characterization of a novel phosphatase from the Arabidopsis thaliana gene locus At1g05000.

Journal: Proteins 20081001

Title: Regulation of insulin receptor substrate-1 expression levels by caveolin-1.

Journal: Journal of cellular physiology 20081001

Title: Tyrosine phosphorylation and Ras activation is required for hydrogen peroxide-mediated Raf-1 kinase activation.

Journal: Molecular and cellular biochemistry 20081001

Title: Increased activity of the human sperm tyrosine kinase SRC by the cAMP-dependent pathway in the presence of calcium.

Journal: Biology of reproduction 20081001

Title: Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes.

Journal: Blood 20081001

Title: Both EGFR kinase and Src-related tyrosine kinases regulate human ether-à-go-go-related gene potassium channels.

Journal: Cellular signalling 20081001

Title: Identification of a functional interaction between Kv4.3 channels and c-Src tyrosine kinase.

Journal: Biochimica et biophysica acta 20081001

Title: Erythropoietin receptor-mediated Egr-1 activation: structural requirements and functional implications.

Journal: Cellular signalling 20081001

Title: Integrin-associated protein association with SRC homology 2 domain containing tyrosine phosphatase substrate 1 regulates igf-I signaling in vivo.

Journal: Diabetes 20081001

Title: Muscle-specific IRS-1 Ser->Ala transgenic mice are protected from fat-induced insulin resistance in skeletal muscle.

Journal: Diabetes 20081001

Title: Analysis of the calcium-dependent regulation of proline-rich tyrosine kinase 2 by gonadotropin-releasing hormone.

Journal: Molecular endocrinology (Baltimore, Md.) 20081001

Title: G-CSF stimulates Jak2-dependent Gab2 phosphorylation leading to Erk1/2 activation and cell proliferation.

Journal: Cellular signalling 20081001

Title: Critical role of Lck in L-selectin signaling induced by sulfatides engagement.

Journal: Journal of leukocyte biology 20081001

Title: The role of phosphorylated residues in peptide-peptide noncovalent complexes formation.

Journal: Journal of the American Society for Mass Spectrometry 20081001

Title: Involvement of heparan sulfate proteoglycan in sensing hypotonic stress in bovine aortic endothelial cells.

Journal: Biochimica et biophysica acta 20081001

Title: Effect of cryopreservation on phosphorylation state of proteins involved in sperm motility initiation in sea bream.

Journal: Cryobiology 20081001

Title: N-Glycans in cancer progression.

Journal: Glycobiology 20081001

Title: Stat3 contributes to resistance toward BCR-ABL inhibitors in a bone marrow microenvironment model of drug resistance.

Journal: Molecular cancer therapeutics 20081001

Title: [Effect of a novel tyrosine kinase inhibitor HHGV678 on growth inhibition of Bcr-Abl wild type and IM-resistant cell lines in vitro].

Journal: Zhongguo shi yan xue ye xue za zhi 20081001

Title: Organization of physical interactomes as uncovered by network schemas.

Journal: PLoS computational biology 20081001

Title: Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism.

Journal: PLoS biology 20081001

Title: Repetitive N-WASP-binding elements of the enterohemorrhagic Escherichia coli effector EspF(U) synergistically activate actin assembly.

Journal: PLoS pathogens 20081001

Title: Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37.

Journal: Molecular cell 20080926

Title: EphrinB2 induces tyrosine phosphorylation of NR2B via Src-family kinases during inflammatory hyperalgesia.

Journal: Neuroscience 20080922

Title: Eyes absent proteins: characterization of substrate specificity and phosphatase activity of mutants associated with branchial, otic and renal anomalies.

Journal: Chembiochem : a European journal of chemical biology 20080922

Title: The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality.

Journal: Immunity 20080919

Title: Platelet-derived growth factor-alpha receptor activation is required for human cytomegalovirus infection.

Journal: Nature 20080918

Title: Dual MET-EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer.

Journal: British journal of cancer 20080916

Title: Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis.

Journal: The Journal of biological chemistry 20080912

Title: Inadequate activation of the GTPase RhoA contributes to the lack of fibronectin matrix assembly in von Hippel-Lindau protein-defective renal cancer cells.

Journal: The Journal of biological chemistry 20080905

Title: Identification of c-Src tyrosine kinase substrates using mass spectrometry and peptide microarrays.

Journal: Journal of proteome research 20080905

Title: Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation.

Journal: Cell 20080905

Title: Detection of circulating tumour cells in peripheral blood with an automated scanning fluorescence microscope.

Journal: British journal of cancer 20080902

Title: Linear motif atlas for phosphorylation-dependent signaling.

Journal: Science signaling 20080902

Title: Feto-maternal ACP1 activity ratio and intrauterine survival.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20080901

Title: Insights from the energetics of water binding at the domain-ligand interface of the Src SH2 domain.

Journal: Proteins 20080901

Title: The equatorial subsegment in mammalian spermatozoa is enriched in tyrosine phosphorylated proteins.

Journal: Biology of reproduction 20080901

Title: Abi1 gene silencing by short hairpin RNA impairs Bcr-Abl-induced cell adhesion and migration in vitro and leukemogenesis in vivo.

Journal: Carcinogenesis 20080901

Title: Expression and tyrosine phosphorylation of Crk-associated substrate lymphocyte type (Cas-L) protein in human neutrophils.

Journal: Journal of cellular biochemistry 20080901

Title: Cleavage of disulfide bonds in mouse spermatogenic cell-specific type 1 hexokinase isozyme is associated with increased hexokinase activity and initiation of sperm motility.

Journal: Biology of reproduction 20080901

Title: Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics.

Journal: Molecular & cellular proteomics : MCP 20080901

Title: Phosphorylation and kinetics of mammalian cytochrome c oxidase.

Journal: Molecular & cellular proteomics : MCP 20080901

Title: Carcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolism.

Journal: Diabetes 20080901

Title: A subset of signal transduction pathways is required for hippocampal growth cone collapse induced by ephrin-A5.

Journal: Developmental neurobiology 20080901

Title: Somatostatin receptors 1, 2, and 5 cooperate in the somatostatin inhibition of C6 glioma cell proliferation in vitro via a phosphotyrosine phosphatase-eta-dependent inhibition of extracellularly regulated kinase-1/2.

Journal: Endocrinology 20080901

Title: The effect of phosphorylation on the electron capture dissociation of peptide ions.

Journal: Journal of the American Society for Mass Spectrometry 20080901

Title: Immunohistochemical assessment of protein phosphorylation state: the dream and the reality.

Journal: Histochemistry and cell biology 20080901

Title: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver.

Journal: The FEBS journal 20080901

Title: Pigment epithelium-derived factor (PEDF) ameliorates advanced glycation end product (AGE)-induced hepatic insulin resistance in vitro by suppressing Rac-1 activation.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20080901

Title: Rats with monosodium glutamate-induced obesity and insulin resistance exhibit low expression of Galpha(i2) G-protein.

Journal: General physiology and biophysics 20080901

Title: Talin depletion reveals independence of initial cell spreading from integrin activation and traction.

Journal: Nature cell biology 20080901

Title: Therapeutic options in the management of acromegaly: focus on lanreotide Autogel.

Journal: Biologics : targets & therapy 20080901

Title: Kinetic characterization of O-phospho-L-tyrosine phosphohydrolase activity of two fungal phytases.

Journal: Journal of agricultural and food chemistry 20080827

Title: System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties.

Journal: Chemistry & biology 20080825

Title: Phosphorylation of the Arp2/3 complex is necessary to nucleate actin filaments.

Journal: The Journal of cell biology 20080825

Title: Crystal structure of the human Fe65-PTB1 domain.

Journal: The Journal of biological chemistry 20080822

Title: Prosaposin is an AR-target gene and its neurotrophic domain upregulates AR expression and activity in prostate stromal cells.

Journal: Journal of cellular biochemistry 20080815

Title: Tyrosine phosphorylation modifies protein kinase C delta-dependent phosphorylation of cardiac troponin I.

Journal: The Journal of biological chemistry 20080815

Title: The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVH genes.

Journal: Blood 20080815

Title: Genome wide analysis of pathogenic SH2 domain mutations.

Journal: Proteins 20080801

Title: Regulation of phosphate homeostasis by the phosphatonins and other novel mediators.

Journal: Pediatric nephrology (Berlin, Germany) 20080801

Title: TGF-beta inhibits prolactin-induced expression of beta-casein by a Smad3-dependent mechanism.

Journal: Journal of cellular biochemistry 20080801

Title: Integrin activation in bovine placentomes and in caruncular epithelial cells isolated from pregnant cows.

Journal: Biology of reproduction 20080801

Title: Protein tyrosine phosphatase receptor type Z dephosphorylates TrkA receptors and attenuates NGF-dependent neurite outgrowth of PC12 cells.

Journal: Journal of biochemistry 20080801

Title: Impact of oxidative stress and peroxisome proliferator-activated receptor gamma coactivator-1alpha in hepatic insulin resistance.

Journal: Diabetes 20080801

Title: JAK2, but not Src family kinases, is required for STAT, ERK, and Akt signaling in response to growth hormone in preadipocytes and hepatoma cells.

Journal: Molecular endocrinology (Baltimore, Md.) 20080801

Title: Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells.

Journal: Molecular endocrinology (Baltimore, Md.) 20080801

Title: Global impact of oncogenic Src on a phosphotyrosine proteome.

Journal: Journal of proteome research 20080801

Title: TiO(2)-based phosphoproteomic analysis of the plasma membrane and the effects of phosphatase inhibitor treatment.

Journal: Journal of proteome research 20080801

Title: The receptor phosphatase HmLAR2 collaborates with focal adhesion proteins in filopodial tips to control growth cone morphology.

Journal: Developmental biology 20080801

Title: New roles for pyruvate kinase M2: working out the Warburg effect.

Journal: Trends in biochemical sciences 20080801

Title: CaMK-II promotes focal adhesion turnover and cell motility by inducing tyrosine dephosphorylation of FAK and paxillin.

Journal: Cell motility and the cytoskeleton 20080801

Title: Impaired tyrosine phosphorylation of membrane type 1-matrix metalloproteinase reduces tumor cell proliferation in three-dimensional matrices and abrogates tumor growth in mice.

Journal: Carcinogenesis 20080801

Title: An enriching phosphotyrosine experience for Src substrates.

Journal: Journal of proteome research 20080801

Title: The NDR/LATS family kinase Cbk1 directly controls transcriptional asymmetry.

Journal: PLoS biology 20080801

Title: Phosphoinositide-3 kinase-Akt pathway controls cellular entry of Ebola virus.

Journal: PLoS pathogens 20080801

Title: [Regulatory effects of Shc-related phosphotyrosine adaptor proteins on aging].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080801

Title: The renin-angiotensin system and diabetes: an update.

Journal: Vascular health and risk management 20080801

Title: Can systems biology understand pathway activation? Gene expression signatures as surrogate markers for understanding the complexity of pathway activation.

Journal: Current genomics 20080801

Title: The PPLA motif of glycogen synthase kinase 3beta is required for interaction with Fe65.

Journal: Molecules and cells 20080731

Title: A DFT study on the formation of a phosphohistidine intermediate in prostatic acid phosphatase.

Journal: Journal of the American Chemical Society 20080730

Title: Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis.

Journal: Biochemistry 20080729

Title: A high affinity hepatocyte growth factor-binding site in the immunoglobulin-like region of Met.

Journal: The Journal of biological chemistry 20080725

Title: Mitogen-activated protein kinase phosphatase-1 represses c-Jun NH2-terminal kinase-mediated apoptosis via NF-kappaB regulation.

Journal: The Journal of biological chemistry 20080725

Title: Capture of phosphopeptides using alpha-zirconium phosphate nanoplatelets.

Journal: Analytical chemistry 20080715

Title: A re-examination of the difluoromethylenesulfonic acid group as a phosphotyrosine mimic for PTP1B inhibition.

Journal: Bioorganic & medicinal chemistry 20080715

Title: A wide-ranging cellular response to UV damage of DNA.

Journal: Cell cycle (Georgetown, Tex.) 20080715

Title: Context-dependent fluorescence detection of a phosphorylated tyrosine residue by a ribonucleopeptide.

Journal: Journal of the American Chemical Society 20080709

Title: TLR-independent induction of human monocyte IL-1 by phosphoglycolipids from thermophilic bacteria.

Journal: Glycoconjugate journal 20080701

Title: Organization of multiprotein complexes at cell-cell junctions.

Journal: Histochemistry and cell biology 20080701

Title: CD44 mobilization in allogeneic dendritic cell-T cell immunological synapse plays a key role in T cell activation.

Journal: Journal of leukocyte biology 20080701

Title: Glypican-3-mediated oncogenesis involves the Insulin-like growth factor-signaling pathway.

Journal: Carcinogenesis 20080701

Title: Hyperglycemia-induced reactive oxygen species toxicity to endothelial cells is dependent on paracrine mediators.

Journal: Diabetes 20080701

Title: SHPS-1/SIRP1alpha contributes to interleukin-6 signalling.

Journal: Cellular signalling 20080701

Title: Focal adhesion kinase and beta1 integrin regulation of Na+, K+, 2Cl- cotransporter in osmosensing ion transporting cells of killifish, Fundulus heteroclitus.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20080701

Title: The adaptor 3BP2 activates CD244-mediated cytotoxicity in PKC- and SAP-dependent mechanisms.

Journal: Molecular immunology 20080701

Title: Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo.

Journal: American journal of physiology. Renal physiology 20080701

Title: Phosphoprotein profiling by PA-GeLC-MS/MS.

Journal: Journal of proteome research 20080701

Title: Role of the C-terminal SH3 domain and N-terminal tyrosine phosphorylation in regulation of Tim and related Dbl-family proteins.

Journal: Biochemistry 20080701

Title: Immunoaffinity enrichments followed by mass spectrometric detection for studying global protein tyrosine phosphorylation.

Journal: Journal of proteome research 20080701

Title: MEK1/2 induces STAT5-mediated germline transcription of the TCRgamma locus in response to IL-7R signaling.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20080701

Title: Tumor-induced suppressor of cytokine signaling 3 inhibits toll-like receptor 3 signaling in dendritic cells via binding to tyrosine kinase 2.

Journal: Cancer research 20080701

Title: Insulin resistance associated to obesity: the link TNF-alpha.

Journal: Archives of physiology and biochemistry 20080701

Title: Gain-of-function mutations in the extracellular domain of KIT are common in canine mast cell tumors.

Journal: Molecular cancer research : MCR 20080701

Title: Intracellular signaling by Akt: bound to be specific.

Journal: Science signaling 20080617

Title: CLEC9A is a novel activation C-type lectin-like receptor expressed on BDCA3+ dendritic cells and a subset of monocytes.

Journal: The Journal of biological chemistry 20080613

Title: Post-translational regulation of the ERK phosphatase DUSP6/MKP3 by the mTOR pathway.

Journal: Oncogene 20080612

Title: FGFR4 and its novel splice form in myogenic cells: Interplay of glycosylation and tyrosine phosphorylation.

Journal: Journal of cellular physiology 20080601

Title: Src-Tyrosine kinases are major agents in mitochondrial tyrosine phosphorylation.

Journal: Journal of cellular biochemistry 20080601

Title: Stable isotopic labeling by amino acids in cultured primary neurons: application to brain-derived neurotrophic factor-dependent phosphotyrosine-associated signaling.

Journal: Molecular & cellular proteomics : MCP 20080601

Title: Identification of the molecular chaperone, heat shock protein 1 (chaperonin 10), in the reproductive tract and in capacitating spermatozoa in the male mouse.

Journal: Biology of reproduction 20080601

Title: Characterization of the RET protooncogene transmembrane domain mutation S649L associated with nonaggressive medullary thyroid carcinoma.

Journal: European journal of endocrinology 20080601

Title: GTP avoidance in Tetrahymena thermophila requires tyrosine kinase activity, intracellular calcium, NOS, and guanylyl cyclase.

Journal: Purinergic signalling 20080601

Title: Impact of the FcgammaII-receptor on quartz uptake and inflammatory response by alveolar macrophages.

Journal: American journal of physiology. Lung cellular and molecular physiology 20080601

Title: TCR-induced downregulation of protein tyrosine phosphatase PEST augments secondary T cell responses.

Journal: Molecular immunology 20080601

Title: A quantitative study of the recruitment potential of all intracellular tyrosine residues on EGFR, FGFR1 and IGF1R.

Journal: Molecular bioSystems 20080601

Title: The virus-like particles of a braconid endoparasitoid wasp, Meteorus pulchricornis, inhibit hemocyte spreading in its noctuid host, Pseudaletia separata.

Journal: Journal of insect physiology 20080601

Title: Stem cell factor and its receptor, c-kit, are important for hepatocyte proliferation in wild-type and tumor necrosis factor receptor-1 knockout mice after 70% hepatectomy.

Journal: Surgery 20080601

Title: Model-based hypothesis testing of key mechanisms in initial phase of insulin signaling.

Journal: PLoS computational biology 20080601

Title: Inhibition of ZAP-70 kinase activity via an analog-sensitive allele blocks T cell receptor and CD28 superagonist signaling.

Journal: The Journal of biological chemistry 20080530

Title: Activation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65.

Journal: The Journal of biological chemistry 20080523

Title: Roles of Necl-5/poliovirus receptor and Rho-associated kinase (ROCK) in the regulation of transformation of integrin alpha(V)beta(3)-based focal complexes into focal adhesions.

Journal: The Journal of biological chemistry 20080523

Title: Development of electrochemical calcium sensors by using silicon nanowires modified with phosphotyrosine.

Journal: Biosensors & bioelectronics 20080515

Title: Somatostatin/somatostatin receptor signalling: phosphotyrosine phosphatases.

Journal: Molecular and cellular endocrinology 20080514

Title: Substitution of pseudokinase domain residue Val-617 by large non-polar amino acids causes activation of JAK2.

Journal: The Journal of biological chemistry 20080509

Title: TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia.

Journal: The Journal of biological chemistry 20080509

Title: EML4-ALK fusion transcript is not found in gastrointestinal and breast cancers.

Journal: British journal of cancer 20080506

Title: Identification of disulfide-linked dimers of the receptor tyrosine kinase DDR1.

Journal: The Journal of biological chemistry 20080502

Title: LC/MS identification of 12 intracellular cytoskeletal and inflammatory proteins from monocytes adherent on surface-adsorbed fibronectin-derived peptides.

Journal: Journal of biomedical materials research. Part A 20080501

Title: Insulin growth factor signaling mediates neuron-like differentiation of adipose-tissue-derived stem cells.

Journal: Differentiation; research in biological diversity 20080501

Title: Targets of tyrosine nitration in diabetic rat retina.

Journal: Molecular & cellular proteomics : MCP 20080501

Title: Ex vivo induction of mRNA in human whole blood as a new platform of drug and dietary supplement development.

Journal: Pharmaceutical research 20080501

Title: Glycosylation of IgG B cell receptor (IgG BCR) in multiple myeloma: relationship between sialylation and the signal activity of IgG BCR.

Journal: Glycoconjugate journal 20080501

Title: Allosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1.

Journal: Biochimica et biophysica acta 20080501

Title: Endosomal NADPH oxidase regulates c-Src activation following hypoxia/reoxygenation injury.

Journal: The Biochemical journal 20080501

Title: Ecto-phosphatase activity on the external surface of Rhodnius prolixus salivary glands: modulation by carbohydrates and Trypanosoma rangeli.

Journal: Acta tropica 20080501

Title: Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts.

Journal: Nature cell biology 20080501

Title: Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase.

Journal: Bioorganic & medicinal chemistry letters 20080501

Title: Mercury-induced crystallization and SAD phasing of the human Fe65-PTB1 domain.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20080501

Title: Overproduction, purification, crystallization and preliminary X-ray analysis of human Fe65-PTB2 in complex with the amyloid precursor protein intracellular domain.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20080501

Title: The parasexual cycle in Candida albicans provides an alternative pathway to meiosis for the formation of recombinant strains.

Journal: PLoS biology 20080501

Title: Identification of phosphotyrosyl proteins in vitreous humours of patients with vitreoretinal diseases by sodium dodecyl sulphate-polyacrylamide gel electrophoresis/Western blotting/matrix-assisted laser desorption time-of-flight mass spectrometry.

Journal: Annals of clinical biochemistry 20080501

Title: A transgenic Drosophila model demonstrates that the Helicobacter pylori CagA protein functions as a eukaryotic Gab adaptor.

Journal: PLoS pathogens 20080501

Title: Genome analysis of the unicellular green alga Chlamydomonas reinhardtii Indicates an ancient evolutionary origin for key pattern recognition and cell-signaling protein families.

Journal: Genetics 20080501

Title: Raf activation is regulated by tyrosine 510 phosphorylation in Drosophila.

Journal: PLoS biology 20080501

Title: Interplay between acid phosphatase and cysteine proteases in mediating vitellin degradation during early embryogenesis of Periplaneta americana.

Journal: Journal of insect physiology 20080501

Title: The Bro1-related protein HD-PTP/PTPN23 is required for endosomal cargo sorting and multivesicular body morphogenesis.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20080429

Title: The mechanism of anti-platelet activity of davallialactone: involvement of intracellular calcium ions, extracellular signal-regulated kinase 2 and p38 mitogen-activated protein kinase.

Journal: European journal of pharmacology 20080428

Title: Smad4-dependent TGF-beta signaling suppresses RON receptor tyrosine kinase-dependent motility and invasion of pancreatic cancer cells.

Journal: The Journal of biological chemistry 20080425

Title: N-->O-Acyl shift in Fmoc-based synthesis of phosphopeptides.

Journal: Organic & biomolecular chemistry 20080421

Title: Requirement of adaptor protein GULP during stabilin-2-mediated cell corpse engulfment.

Journal: The Journal of biological chemistry 20080418

Title: Evaluation of protein kinase activities of cell lysates using peptide microarrays based on surface plasmon resonance imaging.

Journal: Analytical biochemistry 20080415

Title: Subcellular receptor redistribution and enhanced microspike formation by a Ret receptor preferentially recruiting Dok.

Journal: Neuroscience letters 20080411

Title: Synthesis, characterization and Stat3 inhibitory properties of the prototypical platinum(IV) anticancer drug, [PtCl3(NO2)(NH3)2] (CPA-7).

Journal: Inorganic chemistry 20080407

Title: Identification of new tyrosine phosphorylated proteins in rat brain mitochondria.

Journal: FEBS letters 20080402

Title: Effects of carboxyamidotriazole on in vitro models of imatinib-resistant chronic myeloid leukemia.

Journal: Journal of cellular physiology 20080401

Title: Prostatic-like acid phosphatase in human endometrial glands and its cyclic activity.

Journal: Journal of molecular histology 20080401

Title: Insulin resistance induced by tumor necrosis factor-alpha in myocytes and brown adipocytes.

Journal: Journal of animal science 20080401

Title: Morphoregulation by acetylcholinesterase in fibroblasts and astrocytes.

Journal: Journal of cellular physiology 20080401

Title: Defining the specificity space of the human SRC homology 2 domain.

Journal: Molecular & cellular proteomics : MCP 20080401

Title: Cysteine-rich protein 61 and connective tissue growth factor induce deadhesion and anoikis of retinal pericytes.

Journal: Endocrinology 20080401

Title: Impaired intercellular adhesion and immature adherens junctions in merlin-deficient human primary schwannoma cells.

Journal: Glia 20080401

Title: FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival.

Journal: Cancer research 20080401

Title: FGF19 exhibits neuroprotective effects on adult mammalian photoreceptors in vitro.

Journal: Investigative ophthalmology & visual science 20080401

Title: Genome-wide prediction of SH2 domain targets using structural information and the FoldX algorithm.

Journal: PLoS computational biology 20080401

Title: Hyperphosphorylated cortactin in cancer cells plays an inhibitory role in cell motility.

Journal: Molecular cancer research : MCR 20080401

Title: Tac-beta1 inhibits FAK activation and Src signaling.

Journal: Biochemical and biophysical research communications 20080328

Title: Regulation of adaptor protein GIT1 in platelets, leading to the interaction between GIT1 and integrin alpha(IIb)beta3.

Journal: Biochemical and biophysical research communications 20080328

Title: The highly repetitive region of the Helicobacter pylori CagY protein comprises tandem arrays of an alpha-helical repeat module.

Journal: Journal of molecular biology 20080328

Title: Activity of lapatinib a novel HER2 and EGFR dual kinase inhibitor in human endometrial cancer cells.

Journal: British journal of cancer 20080325

Title: The inhibitory receptor LILRB1 modulates the differentiation and regulatory potential of human dendritic cells.

Journal: Blood 20080315

Title: Ezrin is a target for oncogenic Kit mutants in murine erythroleukemia.

Journal: Blood 20080315

Title: Modulation of gold(III) porphyrin 1a-induced apoptosis by mitogen-activated protein kinase signaling pathways.

Journal: Biochemical pharmacology 20080315

Title: Pyruvate kinase M2 is a phosphotyrosine-binding protein.

Journal: Nature 20080313

Title: Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates.

Journal: The EMBO journal 20080305

Title: Insulin signaling stimulates insulin transport by bovine aortic endothelial cells.

Journal: Diabetes 20080301

Title: GM1-induced activation of phosphatidylinositol 3-kinase: involvement of Trk receptors.

Journal: Journal of neurochemistry 20080301

Title: Activation of protein kinase Cepsilon stimulates DNA-repair via epidermal growth factor receptor nuclear accumulation.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20080301

Title: Focal adhesion kinase as well as p130Cas and paxillin is crucially involved in the enhanced malignant properties under expression of ganglioside GD3 in melanoma cells.

Journal: Biochimica et biophysica acta 20080301

Title: Mitochondrial H2O2 limits U937 cell survival to peroxynitrite by promoting ERK1/2 dephosphorylation.

Journal: Biochimica et biophysica acta 20080301

Title: Initiation of human myoblast differentiation via dephosphorylation of Kir2.1 K+ channels at tyrosine 242.

Journal: Development (Cambridge, England) 20080301

Title: Analysis of the cell adhesion molecule sticks-and-stones reveals multiple redundant functional domains, protein-interaction motifs and phosphorylated tyrosines that direct myoblast fusion in Drosophila melanogaster.

Journal: Genetics 20080301

Title: Tandem immunoprecipitation of phosphotyrosine-mass spectrometry (TIPY-MS) indicates C19ORF19 becomes tyrosine-phosphorylated and associated with activated epidermal growth factor receptor.

Journal: Journal of proteome research 20080301

Title: Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2.

Journal: Nature structural & molecular biology 20080301

Title: SpvC is a Salmonella effector with phosphothreonine lyase activity on host mitogen-activated protein kinases.

Journal: Molecular microbiology 20080301

Title: Immunohistochemical analysis of phosphotyrosine signal transducer and activator of transcription 3 and epidermal growth factor receptor autocrine signaling pathways in head and neck cancers and metastatic lymph nodes.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080301

Title: When a domain is not a domain.

Journal: Nature structural & molecular biology 20080301

Title: A label-free quantification method by MS/MS TIC compared to SILAC and spectral counting in a proteomics screen.

Journal: Proteomics 20080301

Title: RNA interference screen identifies Abl kinase and PDGFR signaling in Chlamydia trachomatis entry.

Journal: PLoS pathogens 20080301

Title: Chlamydial entry involves TARP binding of guanine nucleotide exchange factors.

Journal: PLoS pathogens 20080301

Title: Genomic organization and control of the grb7 gene family.

Journal: Current genomics 20080301

Title: Protein kinase assay on peptide-conjugated gold nanoparticles.

Journal: Biosensors & bioelectronics 20080227

Title: An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on Dok1 and talin binding.

Journal: The Journal of biological chemistry 20080227

Title: Mutations causing DOK7 congenital myasthenia ablate functional motifs in Dok-7.

Journal: The Journal of biological chemistry 20080227

Title: A critical role for Lyn in acute myeloid leukemia.

Journal: Blood 20080215

Title: Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts.

Journal: Blood 20080215

Title: The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans.

Journal: Nature 20080214

Title: The JIP1 scaffold protein regulates axonal development in cortical neurons.

Journal: Current biology : CB 20080212

Title: Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene.

Journal: Molecular psychiatry 20080201

Title: Constitutive nuclear import of latent and activated STAT5a by its coiled coil domain.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080201

Title: Involvement of cortactin and phosphotyrosine proteins in cell-cell contact formation in cultured bovine corneal endothelial cells.

Journal: Histochemistry and cell biology 20080201

Title: Suppression of FUT1/FUT4 expression by siRNA inhibits tumor growth.

Journal: Biochimica et biophysica acta 20080201

Title: A photoswitchable ITAM peptidomimetic: synthesis and real time surface plasmon resonance (SPR) analysis of the effects of cis-trans isomerization on binding.

Journal: Bioorganic & medicinal chemistry 20080201

Title: Membrane targeting by APPL1 and APPL2: dynamic scaffolds that oligomerize and bind phosphoinositides.

Journal: Traffic (Copenhagen, Denmark) 20080201

Title: Memo is homologous to nonheme iron dioxygenases and binds an ErbB2-derived phosphopeptide in its vestigial active site.

Journal: The Journal of biological chemistry 20080201

Title: Regulation of FynT function by dual domain docking on PAG/Cbp.

Journal: The Journal of biological chemistry 20080201

Title: The microtubule-associated protein tau is phosphorylated by Syk.

Journal: Biochimica et biophysica acta 20080201

Title: Breast tumor kinase BRK requires kinesin-2 subunit KAP3A in modulation of cell migration.

Journal: Cellular signalling 20080201

Title: Ezrin is a specific and direct target of protein tyrosine phosphatase PRL-3.

Journal: Biochimica et biophysica acta 20080201

Title: Topology of molecular machines of the endoplasmic reticulum: a compilation of proteomics and cytological data.

Journal: Histochemistry and cell biology 20080201

Title: Overexpression of EPHA2 receptor destabilizes adherens junctions via a RhoA-dependent mechanism.

Journal: Journal of cell science 20080201

Title: Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors.

Journal: European journal of immunology 20080201

Title: Phosphorylation and nuclear translocation of STAT3 regulated by the Epstein-Barr virus latent membrane protein 1 in nasopharyngeal carcinoma.

Journal: International journal of molecular medicine 20080201

Title: Extracellular acidic environments induce phosphorylation of ZAP-70 in Jurkat T cells.

Journal: Immunology letters 20080129

Title: Regulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) by Src involves tyrosine phosphorylation of PDK1 and Src homology 2 domain binding.

Journal: The Journal of biological chemistry 20080118

Title: Minimal role for STAT1 in interleukin-6 signaling and actions in the murine brain.

Journal: Glia 20080115

Title: A highly efficient route to enantiomerically pure l-N-Bz-Pmp(t-Bu)2-OH and incorporation into a peptide-based protein tyrosine phosphatase inhibitor.

Journal: Bioorganic & medicinal chemistry letters 20080115

Title: Siah proteins induce the epidermal growth factor-dependent degradation of phospholipase Cepsilon.

Journal: The Journal of biological chemistry 20080111

Title: Structure of the human protein kinase MPSK1 reveals an atypical activation loop architecture.

Journal: Structure (London, England : 1993) 20080108

Title: Phosphorylation, desensitization and internalization of human alpha1B-adrenoceptors induced by insulin-like growth factor-I.

Journal: European journal of pharmacology 20080106

Title: Skin testing correlates negatively with high-activity ACP1 *B/*C genotype.

Journal: International archives of allergy and immunology 20080101

Title: Phorbol ester and hydrogen peroxide synergistically induce the interaction of diacylglycerol kinase gamma with the Src homology 2 and C1 domains of beta2-chimaerin.

Journal: The Biochemical journal 20080101

Title: An enhanced association of RACK1 with Abl in cells transfected with oncogenic ras.

Journal: The international journal of biochemistry & cell biology 20080101

Title: Inhibition of tyrosine kinase activity prevents the adhesive and cohesive properties of platelets and the expression of procoagulant activity in response to collagen.

Journal: Thrombosis research 20080101

Title: Src family kinases: regulation of their activities, levels and identification of new pathways.

Journal: Biochimica et biophysica acta 20080101

Title: The impact of delay in cryo-fixation on biomarkers of Src tyrosine kinase activity in human breast and bladder cancers.

Journal: Cancer chemotherapy and pharmacology 20080101

Title: The PTB domain of tensin: NMR solution structure and phosphoinositides binding studies.

Journal: Biopolymers 20080101

Title: A2 isoform of mammalian translation factor eEF1A displays increased tyrosine phosphorylation and ability to interact with different signalling molecules.

Journal: The international journal of biochemistry & cell biology 20080101

Title: Motif decomposition of the phosphotyrosine proteome reveals a new N-terminal binding motif for SHIP2.

Journal: Molecular & cellular proteomics : MCP 20080101

Title: Increase of doxorubicin-induced apoptosis after knock-down of gonadotropin-releasing hormone receptor expression in human endometrial, ovarian and breast cancer cells.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20080101

Title: Molecular mechanisms of the antiproliferative activity of somatostatin receptors (SSTRs) in neuroendocrine tumors.

Journal: Frontiers in bioscience : a journal and virtual library 20080101

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

Journal: Journal of proteome research 20080101

Title: Structural basis for the binding of high affinity phosphopeptides to Stat3.

Journal: Biopolymers 20080101

Title: Mass spectrometric detection of tyrosine sulfation in human pancreatic trypsinogens, but not in tumor-associated trypsinogen.

Journal: The FEBS journal 20080101

Title: Molecular events involved in the increased expression of matrix metalloproteinase-9 by T lymphocytes of mammary tumor-bearing mice.

Journal: International journal of molecular medicine 20080101

Title: Multiple paxillin binding sites regulate FAK function.

Journal: Journal of molecular signaling 20080101

Title: SCOWLP classification: structural comparison and analysis of protein binding regions.

Journal: BMC bioinformatics 20080101

Title: CD47 associates with alpha 5 integrin and regulates responses of human articular chondrocytes to mechanical stimulation in an in vitro model.

Journal: Arthritis research & therapy 20080101

Title: Host-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transduction.

Journal: BMC systems biology 20080101

Title: Drosophila cbl is essential for control of cell death and cell differentiation during eye development.

Journal: PloS one 20080101

Title: PI-3K/Akt pathway-dependent cyclin D1 expression is responsible for arsenite-induced human keratinocyte transformation.

Journal: Environmental health perspectives 20080101

Title: Cytosolic extract induces Tir translocation and pedestals in EPEC-infected red blood cells.

Journal: PLoS pathogens 20080101

Title: Serotonin (5-HT) transport in human platelets is modulated by Src-catalysed Tyr-phosphorylation of the plasma membrane transporter SERT.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

Title: Taurolithocholic acid-3 sulfate impairs insulin signaling in cultured rat hepatocytes and perfused rat liver.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

Title: A novel ZAP-70 dependent FRET based biosensor reveals kinase activity at both the immunological synapse and the antisynapse.

Journal: PloS one 20080101

Title: Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting.

Journal: PLoS medicine 20080101

Title: Transcription-dependent epidermal growth factor receptor activation by hepatocyte growth factor.

Journal: Molecular cancer research : MCR 20080101

Title: Redundancy and compensation in axon guidance: genetic analysis of the Drosophila Ptp10D/Ptp4E receptor tyrosine phosphatase subfamily.

Journal: Neural development 20080101

Title: Protein tyrosine phosphatase-1B (PTP1B) helps regulate EGF-induced stimulation of S-phase entry in human corneal endothelial cells.

Journal: Molecular vision 20080101

Title: Prolactin receptor signaling is essential for perinatal brown adipocyte function: a role for insulin-like growth factor-2.

Journal: PloS one 20080101

Title: Differential effects of age on circulating and splenic leukocyte populations in C57BL/6 and BALB/c male mice.

Journal: Immunity & ageing : I & A 20080101

Title: HLA-DR alpha 2 mediates negative signalling via binding to Tirc7 leading to anti-inflammatory and apoptotic effects in lymphocytes in vitro and in vivo.

Journal: PloS one 20080101

Title: Prevention of hypovolemic circulatory collapse by IL-6 activated Stat3.

Journal: PloS one 20080101

Title: The differentiation/retrodifferentiation program of human U937 leukemia cells is accompanied by changes of VCP/p97.

Journal: BMC cell biology 20080101

Title: Proteomic analysis of the secretome of Leishmania donovani.

Journal: Genome biology 20080101

Title: A cross-talk between TrkB and Ret tyrosine kinases receptors mediates neuroblastoma cells differentiation.

Journal: PloS one 20080101

Title: Dramatic inhibition of osteoclast sealing ring formation and bone resorption in vitro by a WASP-peptide containing pTyr294 amino acid.

Journal: Journal of molecular signaling 20080101

Title: The Gammaherpesvirus m2 protein manipulates the Fyn/Vav pathway through a multidocking mechanism of assembly.

Journal: PloS one 20080101

Title: Protein tyrosine phosphatases: new markers and targets in oncology?

Journal: Current oncology (Toronto, Ont.) 20080101

Title: S100A7-downregulation inhibits epidermal growth factor-induced signaling in breast cancer cells and blocks osteoclast formation.

Journal: PloS one 20080101

Title: Topological analysis of MAPK cascade for kinetic ErbB signaling.

Journal: PloS one 20080101

Title: The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of Src.

Journal: PloS one 20080101

Title: Charge environments around phosphorylation sites in proteins.

Journal: BMC structural biology 20080101

Title: Quantitative multicolor compositional imaging resolves molecular domains in cell-matrix adhesions.

Journal: PloS one 20080101

Title: Characterization and site-directed mutagenesis of Wzb, an O-phosphatase from Lactobacillus rhamnosus.

Journal: BMC biochemistry 20080101

Title: Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cgamma at the centrosome.

Journal: Molecular cancer 20080101

Title: Erwin Schroedinger, Francis Crick and epigenetic stability.

Journal: Biology direct 20080101

Title: The IBR5 phosphatase promotes Arabidopsis auxin responses through a novel mechanism distinct from TIR1-mediated repressor degradation.

Journal: BMC plant biology 20080101

Title: A systems biology approach to analyse amplification in the JAK2-STAT5 signalling pathway.

Journal: BMC systems biology 20080101

Title: Calculation of absolute protein-ligand binding constants with the molecular dynamics free energy perturbation method.

Journal: Methods in molecular biology (Clifton, N.J.) 20080101

Title: Large-scale phosphorylation mapping reveals the extent of tyrosine phosphorylation in Arabidopsis.

Journal: Molecular systems biology 20080101

Title: The clathrin-binding motif and the J-domain of Drosophila Auxilin are essential for facilitating Notch ligand endocytosis.

Journal: BMC developmental biology 20080101

Title: Mammalian liver cytochrome c is tyrosine-48 phosphorylated in vivo, inhibiting mitochondrial respiration.

Journal: Biochimica et biophysica acta 20080101

Title: CD45RB is a novel molecular therapeutic target to inhibit Abeta peptide-induced microglial MAPK activation.

Journal: PloS one 20080101

Title: Reduced paxillin expression contributes to the antimetastatic effect of 4-hydroxycoumarin on B16-F10 melanoma cells.

Journal: Cancer cell international 20080101

Title: Modulatory role of phospholipase D in the activation of signal transducer and activator of transcription (STAT)-3 by thyroid oncogenic kinase RET/PTC.

Journal: BMC cancer 20080101

Title: Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated database of phosphorylation sites.

Journal: BMC bioinformatics 20080101

Title: Modulation of erythrocyte deformability by PKC activity.

Journal: Clinical hemorheology and microcirculation 20080101

Title: SOCS3 inhibiting migration of A549 cells correlates with PYK2 signaling in vitro.

Journal: BMC cancer 20080101

Title: Altered splicing of CEACAM1 in breast cancer: identification of regulatory sequences that control splicing of CEACAM1 into long or short cytoplasmic domain isoforms.

Journal: Molecular cancer 20080101

Title: Functional implications of plasma membrane condensation for T cell activation.

Journal: PloS one 20080101

Title: Expression of the epidermal growth factor receptor (EGFR) and the phosphorylated EGFR in invasive breast carcinomas.

Journal: Breast cancer research : BCR 20080101

Title: Formin 1-isoform IV deficient cells exhibit defects in cell spreading and focal adhesion formation.

Journal: PloS one 20080101

Title: Important genetic checkpoints for insulin resistance in salt-sensitive (S) Dahl rats.

Journal: Cardiovascular diabetology 20080101

Title: Role of X11 and ubiquilin as in vivo regulators of the amyloid precursor protein in Drosophila.

Journal: PloS one 20080101

Title: Reelin induces a radial glial phenotype in human neural progenitor cells by activation of Notch-1.

Journal: BMC developmental biology 20080101

Title: Targeted disruption of the PME-1 gene causes loss of demethylated PP2A and perinatal lethality in mice.

Journal: PloS one 20080101

Title: STAT3 activation in pressure-overloaded feline myocardium: role for integrins and the tyrosine kinase BMX.

Journal: International journal of biological sciences 20080101

Title: Susceptibility to glaucoma: differential comparison of the astrocyte transcriptome from glaucomatous African American and Caucasian American donors.

Journal: Genome biology 20080101

Title: Immunity related genes in dipterans share common enrichment of AT-rich motifs in their 5' regulatory regions that are potentially involved in nucleosome formation.

Journal: BMC genomics 20080101

Title: PPARgamma and Apoptosis in Cancer.

Journal: PPAR research 20080101

Title: Implications of tyrosine phosphoproteomics in cervical carcinogenesis.

Journal: Journal of carcinogenesis 20080101

Title: Expression of clottable protein of tiger shrimp (Penaeus monodon) in gonads and its possible role as nutrient source for the embryo.

Journal: Developmental and comparative immunology 20080101

Title: The central proline rich region of POB1/REPS2 plays a regulatory role in epidermal growth factor receptor endocytosis by binding to 14-3-3 and SH3 domain-containing proteins.

Journal: BMC biochemistry 20080101

Title: The function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters.

Journal: BMC neuroscience 20080101

Title: Skeletal muscle munc18c and syntaxin 4 in human obesity.

Journal: Nutrition & metabolism 20080101

Title: The neurotransmitter dopamine modulates vascular permeability in the endothelium.

Journal: Journal of molecular signaling 20080101

Title: Dynamic expression of Dab2 in the mouse embryonic central nervous system.

Journal: BMC developmental biology 20080101

Title: Germline EPHB2 receptor variants in familial colorectal cancer.

Journal: PloS one 20080101

Title: Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice.

Journal: PloS one 20080101

Title: A RasGAP SH3 peptide aptamer inhibits RasGAP-Aurora interaction and induces caspase-independent tumor cell death.

Journal: PloS one 20080101

Title: HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells.

Journal: PloS one 20080101

Title: Differential expression of Cathepsin S and X in the spinal cord of a rat neuropathic pain model.

Journal: BMC neuroscience 20080101

Title: Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3.

Journal: Breast cancer research : BCR 20080101

Title: Tyrosine phosphorylation of the UDP-glucose dehydrogenase of Escherichia coli is at the crossroads of colanic acid synthesis and polymyxin resistance.

Journal: PloS one 20080101

Title: Overexpression of partner of numb induces asymmetric distribution of the PI4P 5-Kinase Skittles in mitotic sensory organ precursor cells in Drosophila.

Journal: PloS one 20080101

Title: The genetics of feto-placental development: a study of acid phosphatase locus 1 and adenosine deaminase polymorphisms in a consecutive series of newborn infants.

Journal: Reproductive biology and endocrinology : RB&E 20080101

Title: Phosphorylation sites on Tyr28 and the C-terminus of Rad9 are required for inhibition of premature chromosomal condensation across the entire S phase.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

Title: Selective recognition of a tetra-amino-acid motif containing phosphorylated tyrosine residue by ribonucleopeptide.

Journal: Nucleic acids symposium series (2004) 20080101

Title: Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK.

Journal: Molecular cancer 20080101

Title: The protein-phosphatome of the human malaria parasite Plasmodium falciparum.

Journal: BMC genomics 20080101

Title: Phosphorylation of p130Cas initiates Rac activation and membrane ruffling.

Journal: BMC cell biology 20080101

Title: Magic-factor 1, a partial agonist of Met, induces muscle hypertrophy by protecting myogenic progenitors from apoptosis.

Journal: PloS one 20080101

Title: Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines.

Journal: Journal of translational medicine 20080101

Title: P38 MAP kinase signaling is required for the conversion of CD4+CD25- T cells into iTreg.

Journal: PloS one 20080101

Title: The conservation pattern of short linear motifs is highly correlated with the function of interacting protein domains.

Journal: BMC genomics 20080101

Title: Non-opsonic phagocytosis of Legionella pneumophila by macrophages is mediated by phosphatidylinositol 3-kinase.

Journal: PloS one 20080101

Title: Short Linear Motifs recognized by SH2, SH3 and Ser/Thr Kinase domains are conserved in disordered protein regions.

Journal: BMC genomics 20080101

Title: The cell signaling adaptor protein EPS-8 is essential for C. elegans epidermal elongation and interacts with the ankyrin repeat protein VAB-19.

Journal: PloS one 20080101

Title: Quantifying information transfer by protein domains: analysis of the Fyn SH2 domain structure.

Journal: BMC structural biology 20080101

Title: Odin (ANKS1A) is a Src family kinase target in colorectal cancer cells.

Journal: Cell communication and signaling : CCS 20080101

Title: Varicose: a MAGUK required for the maturation and function of Drosophila septate junctions.

Journal: BMC developmental biology 20080101

Title: A phosphotyrosine-imprinted polymer receptor for the recognition of tyrosine phosphorylated peptides.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Title: beta1-integrin mediates myelin-associated glycoprotein signaling in neuronal growth cones.

Journal: Molecular brain 20080101

Title: Fak56 functions downstream of integrin alphaPS3betanu and suppresses MAPK activation in neuromuscular junction growth.

Journal: Neural development 20080101

Title: Signal transduction of fertilization in frog eggs and anti-apoptotic mechanism in human cancer cells: common and specific functions of membrane microdomains.

Journal: The open biochemistry journal 20080101

Title: Gamma-secretase inhibition combined with platinum compounds enhances cell death in a large subset of colorectal cancer cells.

Journal: Cell communication and signaling : CCS 20080101

Title: Significance of the entire C-terminus in biological activities mediated by the RON receptor tyrosine kinase and its oncogenic variant RON160.

Journal: Journal of experimental & clinical cancer research : CR 20080101

Title: Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors.

Journal: PloS one 20080101

Title: Dystroglycan, Tks5 and Src mediated assembly of podosomes in myoblasts.

Journal: PloS one 20080101

Title: The UPS in diabetes and obesity.

Journal: BMC biochemistry 20080101

Title: The marine-derived oligosaccharide sulfate (MdOS), a novel multiple tyrosine kinase inhibitor, combats tumor angiogenesis both in vitro and in vivo.

Journal: PloS one 20080101

Title: Comprehensive dissection of PDGF-PDGFR signaling pathways in PDGFR genetically defined cells.

Journal: PloS one 20080101

Title: Crystal structures of the FAK kinase in complex with TAE226 and related bis-anilino pyrimidine inhibitors reveal a helical DFG conformation.

Journal: PloS one 20080101

Title: Differential roles of the PKC novel isoforms, PKCdelta and PKCepsilon, in mouse and human platelets.

Journal: PloS one 20080101

Title: Induction of galectin-1 expression by HTLV-I Tax and its impact on HTLV-I infectivity.

Journal: Retrovirology 20080101

Title: Cell surface sialylation and fucosylation are regulated by L1 via phospholipase Cgamma and cooperate to modulate neurite outgrowth, cell survival and migration.

Journal: PloS one 20080101

Title: IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis.

Journal: PloS one 20080101

Title: Membrane androgen receptor activation triggers down-regulation of PI-3K/Akt/NF-kappaB activity and induces apoptotic responses via Bad, FasL and caspase-3 in DU145 prostate cancer cells.

Journal: Molecular cancer 20080101

Title: Abelson tyrosine kinase links PDGFbeta receptor activation to cytoskeletal regulation of NMDA receptors in CA1 hippocampal neurons.

Journal: Molecular brain 20080101

Title: Modulation of Src activity by low molecular weight protein tyrosine phosphatase during osteoblast differentiation.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

Title: An incoherent magnetic field inhibited EGF receptor clustering and phosphorylation induced by a 50-Hz magnetic field in cultured FL cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

Title: Pleiotropic effects in Eya3 knockout mice.

Journal: BMC developmental biology 20080101

Title: Phosphorylation regulates SIRT1 function.

Journal: PloS one 20080101

Title: Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.

Journal: Breast cancer research : BCR 20080101

Title: Synergism of EGFR and c-Met pathways, cross-talk and inhibition, in non-small cell lung cancer.

Journal: Journal of carcinogenesis 20080101

Title: [Functioning of tyrosine protein kinases and phosphatases in gastric mucosa cells under conditions of oxidative and nitrosative stress in gastric lesions].

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20080101

Title: Pervanadate stabilizes desmosomes.

Journal: Cell adhesion & migration 20080101

Title: In vitro effects of budesonide on eosinophil-basophil lineage commitment.

Journal: The open respiratory medicine journal 20080101

Title: Antidiabetic Bis-Maltolato-OxoVanadium(IV): conversion of inactive trans- to bioactive cis-BMOV for possible binding to target PTP-1B.

Journal: Drug design, development and therapy 20080101

Title: Development of a HTRF kinase assay for determination of Syk activity.

Journal: Current chemical genomics 20080101

Title: Podosomes and Invadopodia: Related structures with Common Protein Components that May Promote Breast Cancer Cellular Invasion.

Journal: Breast cancer : basic and clinical research 20080101

Title: Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis.

Journal: Clinical and experimental gastroenterology 20080101

Title: Molecular Mechanisms that Regulate Epidermal Growth Factor Receptor Inactivation.

Journal: Clinical medicine. Oncology 20080101

Title: The effect of docetaxel (taxotere) on human gastric cancer cells exhibiting low-dose radiation hypersensitivity.

Journal: Clinical medicine. Oncology 20080101

Title: 53BP2S, interacting with insulin receptor substrates, modulates insulin signaling.

Journal: The Journal of biological chemistry 20071228

Title: Laminin-induced activation of Rac1 and JNKp46 is initiated by Src family kinases and mimics the effects of skeletal muscle contraction.

Journal: Biochemistry 20071225

Title: Chemical DNA damage activates p21 WAF1/CIP1-dependent intra-S checkpoint.

Journal: FEBS letters 20071222

Title: Structural insights into the enzymatic mechanism of the pathogenic MAPK phosphothreonine lyase.

Journal: Molecular cell 20071214

Title: Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.

Journal: Cell 20071214

Title: Endogenous phosphotyrosine signaling in zebrafish embryos.

Journal: Molecular & cellular proteomics : MCP 20071201

Title: Signaling status of IgG B cell receptor (IgG BCR) is indicative for an activated state of circulating B cells in multiple myeloma.

Journal: Annals of hematology 20071201

Title: Role of mitogen-activated protein kinase phosphatases (MKPs) in cancer.

Journal: Cancer metastasis reviews 20071201

Title: Modulation of CD1d-restricted NKT cell responses by CD4.

Journal: Journal of leukocyte biology 20071201

Title: FLT3 regulates beta-catenin tyrosine phosphorylation, nuclear localization, and transcriptional activity in acute myeloid leukemia cells.

Journal: Leukemia 20071201

Title: hTRPC1-associated alpha-actinin, and not hTRPC1 itself, is tyrosine phosphorylated during human platelet activation.

Journal: Journal of thrombosis and haemostasis : JTH 20071201

Title: Synaptic differentiation is defective in mice lacking acetylcholine receptor beta-subunit tyrosine phosphorylation.

Journal: Development (Cambridge, England) 20071201

Title: 3D structure of Syk kinase determined by single-particle electron microscopy.

Journal: Biochimica et biophysica acta 20071201

Title: [Specific recognition and detection of phosphorylated proteins using characteristics of metal ion].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20071201

Title: Inhibition of tyrosine phosphorylation of vascular endothelial growth factor receptors in human umbilical vein endothelial cells: a potent anti-angiogenic lipid-rich extract from shark.

Journal: Journal of medicinal food 20071201

Title: Phosphopeptide elution times in reversed-phase liquid chromatography.

Journal: Journal of chromatography. A 20071116

Title: Oxygen isotopic substitution of peptidyl phosphates for modification-specific mass spectrometry.

Journal: Analytical chemistry 20071115

Title: Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation.

Journal: Structure (London, England : 1993) 20071113

Title: Activation of nonreceptor tyrosine kinase Bmx/Etk mediated by phosphoinositide 3-kinase, epidermal growth factor receptor, and ErbB3 in prostate cancer cells.

Journal: The Journal of biological chemistry 20071109

Title: Platelet-derived growth factor-induced stabilization of cyclooxygenase 2 mRNA in rat smooth muscle cells requires the c-Src family of protein-tyrosine kinases.

Journal: The Journal of biological chemistry 20071109

Title: Role of MAPK phosphatase-1 in sustained activation of JNK during ethanol-induced apoptosis in hepatocyte-like VL-17A cells.

Journal: The Journal of biological chemistry 20071102

Title: Bisperoxovanadium, a phospho-tyrosine phosphatase inhibitor, reprograms myogenic cells to acquire a pluripotent, circulating phenotype.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20071101

Title: Nerve growth factor receptor TrkA signaling in breast cancer cells involves Ku70 to prevent apoptosis.

Journal: Molecular & cellular proteomics : MCP 20071101

Title: Src family tyrosine kinases phosphorylate Flt3 on juxtamembrane tyrosines and interfere with receptor maturation in a kinase-dependent manner.

Journal: Annals of hematology 20071101

Title: Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin.

Journal: Cellular signalling 20071101

Title: Preformed STAT3 transducer complexes in human HepG2 cells and rat hepatocytes.

Journal: Cellular signalling 20071101

Title: Proteomic identification of the cerebral cavernous malformation signaling complex.

Journal: Journal of proteome research 20071101

Title: Proteomic approach for caudal trauma-induced acute phase proteins reveals that creatine kinase is a key acute phase protein in amphioxus humoral fluid.

Journal: Journal of proteome research 20071101

Title: Capillary electrophoresis of phosphorylated amino acids with fluorescence detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071101

Title: Mammalian diaphanous-related formin Dia1 controls the organization of E-cadherin-mediated cell-cell junctions.

Journal: Journal of cell science 20071101

Title: HVEM signaling in monocytes is mediated by intracellular calcium mobilization.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20071101

Title: PTPsigma binds and dephosphorylates neurotrophin receptors and can suppress NGF-dependent neurite outgrowth from sensory neurons.

Journal: Biochimica et biophysica acta 20071101

Title: Progressive loss of epidermal growth factor receptor in a subpopulation of breast cancers: implications in target-directed therapeutics.

Journal: Molecular cancer therapeutics 20071101

Title: Inhibition of estradiol receptor/Src association and cell growth by an estradiol receptor alpha tyrosine-phosphorylated peptide.

Journal: Molecular cancer research : MCR 20071101

Title: Synergistic effect of D-glucose and epidermal growth factor display on dynamic behaviors of human epithelial cells.

Journal: Journal of bioscience and bioengineering 20071101

Title: Tyrosine phosphorylation-dependence of caveolae-mediated endocytosis.

Journal: Journal of cellular and molecular medicine 20071101

Title: Phosphoproteomics.

Journal: Current protocols in protein science 20071101

Title: The control of phosphatidylinositol 3,4-bisphosphate concentrations by activation of the Src homology 2 domain containing inositol polyphosphate 5-phosphatase 2, SHIP2.

Journal: The Biochemical journal 20071015

Title: Regulation of arginine methylation in endothelial cells: role in premature senescence and apoptosis.

Journal: Cell cycle (Georgetown, Tex.) 20071015

Title: alpha-Tocopherol modifies tyrosine phosphorylation and capacitation-like state of cryopreserved porcine sperm.

Journal: Theriogenology 20071015

Title: Liquid chromatographic analysis of phosphoamino acids at femtomole level using chemical derivatization with N-hydroxysuccinimidyl fluorescein-O-acetate.

Journal: Analytica chimica acta 20071003

Title: NPM/ALK binds and phosphorylates the RNA/DNA-binding protein PSF in anaplastic large-cell lymphoma.

Journal: Blood 20071001

Title: Expression, generation, and purification of unphosphorylated and phospho-Ser-380/Thr-382/Thr-383 form of recombinant PTEN phosphatase.

Journal: Protein expression and purification 20071001

Title: Transforming growth factor-beta1 effects on endothelial monolayer permeability involve focal adhesion kinase/Src.

Journal: American journal of respiratory cell and molecular biology 20071001

Title: Suberoylanilide hydroxamic acid (SAHA; vorinostat) suppresses translation of cyclin D1 in mantle cell lymphoma cells.

Journal: Blood 20071001

Title: Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling.

Journal: Blood 20071001

Title: PECAM-1 engagement counteracts ICAM-1-induced signaling in brain vascular endothelial cells.

Journal: Journal of neurochemistry 20071001

Title: Expression of Hsp60 and Grp78 in the human endometrium and oviduct, and their effect on sperm functions.

Journal: Human reproduction (Oxford, England) 20071001

Title: Src regulates phorbol 12-myristate 13-acetate-activated PKC-induced migration via Cas/Crk/Rac1 signaling pathway in glioblastoma cells.

Journal: International journal of molecular medicine 20071001

Title: BDCA2/Fc epsilon RI gamma complex signals through a novel BCR-like pathway in human plasmacytoid dendritic cells.

Journal: PLoS biology 20071001

Title: Natural phosphorylation of CD5 in chronic lymphocytic leukemia B cells and analysis of CD5-regulated genes in a B cell line suggest a role for CD5 in malignant phenotype.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20071001

Title: Fyn regulates the duration of TCR engagement needed for commitment to effector function.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20071001

Title: Role of tyrosine phosphorylation in U46619-induced vasoconstriction of pulmonary vasculature and its modulation by genistein, daidzein, and equol.

Journal: Journal of cardiovascular pharmacology 20071001

Title: A remodelled protease that cleaves phosphotyrosine substrates.

Journal: Journal of the American Chemical Society 20070926

Title: The activation and inhibition of cyclin-dependent kinase-5 by phosphorylation.

Journal: Biochemistry 20070925

Title: Stat5 activation inhibits prolactin-induced AP-1 activity: distinct prolactin-initiated signals in tumorigenesis dependent on cell context.

Journal: Oncogene 20070920

Title: Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding site.

Journal: Journal of medicinal chemistry 20070920

Title: Polymers with tunable toxicity: a reference scale for cytotoxicity testing of biomaterial surfaces.

Journal: Journal of biomedical materials research. Part A 20070915

Title: The low-molecular-weight phosphotyrosine phosphatase is a negative regulator of FcgammaRIIA-mediated cell activation.

Journal: Blood 20070915

Title: Structural basis for UBA-mediated dimerization of c-Cbl ubiquitin ligase.

Journal: The Journal of biological chemistry 20070914

Title: Using measurements of anchoring energies of liquid crystals on surfaces to quantify proteins captured by immobilized ligands.

Journal: Journal of the American Chemical Society 20070912

Title: Role of c-Abl in directing metabolic versus mitogenic effects in insulin receptor signaling.

Journal: The Journal of biological chemistry 20070907

Title: A double tyrosine phosphorylation of P68 RNA helicase confers resistance to TRAIL-induced apoptosis.

Journal: Oncogene 20070906

Title: Antiaggregant effects of Arbutus unedo extracts in human platelets.

Journal: Journal of ethnopharmacology 20070905

Title: L-NAME reverses quinolinic acid-induced toxicity in rat corticostriatal slices: Involvement of src family kinases.

Journal: Journal of neuroscience research 20070901

Title: Protein kinase Cepsilon may act as EGF-inducible scaffold protein for phospholipase Cgamma1.

Journal: Cellular signalling 20070901

Title: Analysis of chaperone proteins associated with human spermatozoa during capacitation.

Journal: Molecular human reproduction 20070901

Title: High tidal volume mechanical ventilation with hyperoxia alters alveolar type II cell adhesion.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070901

Title: Regulation of airway goblet cell mucin secretion by tyrosine phosphorylation signaling pathways.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070901

Title: Kinetics and mechanism of protein tyrosine phosphatase 1B inactivation by acrolein.

Journal: Chemical research in toxicology 20070901

Title: Molecular mechanisms underlying the synergistic induction of CXCL10 by LPS and IFN-gamma in human neutrophils.

Journal: European journal of immunology 20070901

Title: Label-free electrical sensing of small-molecule inhibition on tyrosine phosphorylation.

Journal: Analytical chemistry 20070901

Title: Hypophosphorylated TCR/CD3zeta signals through a Grb2-SOS1-Ras pathway in Lck knockdown cells.

Journal: European journal of immunology 20070901

Title: The radioprotector O-phospho-tyrosine stimulates DNA-repair via epidermal growth factor receptor- and DNA-dependent kinase phosphorylation.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20070901

Title: Higher-energy C-trap dissociation for peptide modification analysis.

Journal: Nature methods 20070901

Title: Signal transduction mechanisms of CD137 ligand in human monocytes.

Journal: Cellular signalling 20070901

Title: Apoptotic killing of HIV-1-infected macrophages is subverted by the viral envelope glycoprotein.

Journal: PLoS pathogens 20070901

Title: Connective tissue progenitor cell growth characteristics on textured substrates.

Journal: International journal of nanomedicine 20070901

Title: PTPL1/FAP-1 negatively regulates TRIP6 function in lysophosphatidic acid-induced cell migration.

Journal: The Journal of biological chemistry 20070817

Title: The commonality of protein interaction networks determined in neurodegenerative disorders (NDDs).

Journal: Bioinformatics (Oxford, England) 20070815

Title: An ultrasensitive high-throughput electrochemiluminescence immunoassay for the Cdc42-associated protein tyrosine kinase ACK1.

Journal: Analytical biochemistry 20070815

Title: Mapping ErbB receptors on breast cancer cell membranes during signal transduction.

Journal: Journal of cell science 20070815

Title: ZRP-1 controls Rho GTPase-mediated actin reorganization by localizing at cell-matrix and cell-cell adhesions.

Journal: Journal of cell science 20070815

Title: Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion.

Journal: British journal of cancer 20070806

Title: Tyk2 mediates effects of urokinase on human vascular smooth muscle cell growth.

Journal: Biochemical and biophysical research communications 20070803

Title: Microtubules regulate PI-3K activity and recruitment to the phagocytic cup during Fcgamma receptor-mediated phagocytosis in nonelicited macrophages.

Journal: Journal of leukocyte biology 20070801

Title: Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life.

Journal: Molecular and cellular biology 20070801

Title: Protein tyrosine dephosphorylation during copper-induced cell death in rice roots.

Journal: Chemosphere 20070801

Title: Systemic analysis of tyrosine phosphorylated proteins in angiopoietin-1 induced signaling pathway of endothelial cells.

Journal: Journal of proteome research 20070801

Title: Sensitivity of breast cancer cells to erlotinib depends on cyclin-dependent kinase 2 activity.

Journal: Molecular cancer therapeutics 20070801

Title: c-Src/histone deacetylase 3 interaction is crucial for hepatocyte growth factor dependent decrease of CXCR4 expression in highly invasive breast tumor cells.

Journal: Molecular cancer research : MCR 20070801

Title: Acute pharmacodynamic and antivascular effects of the vascular endothelial growth factor signaling inhibitor AZD2171 in Calu-6 human lung tumor xenografts.

Journal: Molecular cancer therapeutics 20070801

Title: Therapeutic targeting of nuclear receptor corepressor misfolding in acute promyelocytic leukemia cells with genistein.

Journal: Molecular cancer therapeutics 20070801

Title: A logical model provides insights into T cell receptor signaling.

Journal: PLoS computational biology 20070801

Title: The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications.

Journal: Current genomics 20070801

Title: Synthesis and evaluation of tripodal peptide analogues for cellular delivery of phosphopeptides.

Journal: Journal of medicinal chemistry 20070726

Title: A genetically encoded metabolically stable analogue of phosphotyrosine in Escherichia coli.

Journal: ACS chemical biology 20070720

Title: A lock on phosphotyrosine signaling.

Journal: ACS chemical biology 20070720

Title: Inhibition of epidermal growth factor receptor signalling reduces hypercalcaemia induced by human lung squamous-cell carcinoma in athymic mice.

Journal: British journal of cancer 20070716

Title: Palladin interacts with SH3 domains of SPIN90 and Src and is required for Src-induced cytoskeletal remodeling.

Journal: Experimental cell research 20070715

Title: Cholesterol depletion alters detergent-specific solubility profiles of selected tight junction proteins and the phosphorylation of occludin.

Journal: Experimental cell research 20070715

Title: RACK1 regulates Src activity and modulates paxillin dynamics during cell migration.

Journal: Experimental cell research 20070715

Title: Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1.

Journal: The EMBO journal 20070711

Title: alpha-Tomatine, the major saponin in tomato, induces programmed cell death mediated by reactive oxygen species in the fungal pathogen Fusarium oxysporum.

Journal: FEBS letters 20070710

Title: Full CD3/TCR activation through cholesterol-depleted lipid rafts.

Journal: Cellular signalling 20070701

Title: A transmembrane osteoclastic protein-tyrosine phosphatase regulates osteoclast activity in part by promoting osteoclast survival through c-Src-dependent activation of NFkappaB and JNK2.

Journal: Archives of biochemistry and biophysics 20070701

Title: Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinase.

Journal: Molecular and cellular biology 20070701

Title: Ganglioside GM(3) is stably associated to tyrosine-phosphorylated ErbB2/EGFR receptor complexes and EGFR monomers, but not to ErbB2.

Journal: Biochimica et biophysica acta 20070701

Title: Quantitation of multisite EGF receptor phosphorylation using mass spectrometry and a novel normalization approach.

Journal: Journal of proteome research 20070701

Title: Redox-dependent and ligand-independent trans-activation of insulin receptor by globular adiponectin.

Journal: Hepatology (Baltimore, Md.) 20070701

Title: Defining SH2 domain and PTP specificity by screening combinatorial peptide libraries.

Journal: Methods (San Diego, Calif.) 20070701

Title: Analyzing protein tyrosine phosphatases by phosphotyrosine analog integration.

Journal: Methods (San Diego, Calif.) 20070701

Title: Generation of inhibitor-sensitive protein tyrosine phosphatases via active-site mutations.

Journal: Methods (San Diego, Calif.) 20070701

Title: L-type calcium channels mediate acetylcholine receptor aggregation on cultured muscle.

Journal: Developmental neurobiology 20070701

Title: A role for acetylcholine receptors in their own aggregation on muscle cells.

Journal: Developmental neurobiology 20070701

Title: Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells.

Journal: Proteomics 20070701

Title: Sensitivity analysis of intracellular signaling pathway kinetics predicts targets for stem cell fate control.

Journal: PLoS computational biology 20070701

Title: Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity.

Journal: Molecular cancer therapeutics 20070701

Title: Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli.

Journal: PLoS pathogens 20070701

Title: Study on the mechanisms of an extract of Salvia miltiorrhiza on the regulation of permeability of endothelial cells exposed to tumour necrosis factor-alpha.

Journal: The Journal of pharmacy and pharmacology 20070701

Title: Relaxin signalling in THP-1 cells uses a novel phosphotyrosine-dependent pathway.

Journal: Molecular and cellular endocrinology 20070630

Title: Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro.

Journal: Biochemistry 20070626

Title: High-throughput phosphotyrosine profiling using SH2 domains.

Journal: Molecular cell 20070622

Title: Acquired resistance to erlotinib in A-431 epidermoid cancer cells requires down-regulation of MMAC1/PTEN and up-regulation of phosphorylated Akt.

Journal: Cancer research 20070615

Title: Specific Grb2-mediated interactions regulate clathrin-dependent endocytosis of the cMet-tyrosine kinase.

Journal: The Journal of biological chemistry 20070608

Title: Protein kinase Calpha mediates feedback inhibition of EGF receptor transactivation induced by Gq-coupled receptor agonists.

Journal: Cellular signalling 20070601

Title: Identification of novel fragment compounds targeted against the pY pocket of v-Src SH2 by computational and NMR screening and thermodynamic evaluation.

Journal: Proteins 20070601

Title: Mechanisms of tumour cell invasion and metastasis.

Journal: Journal of molecular medicine (Berlin, Germany) 20070601

Title: The structure-activity relationship of the series of non-peptide small antagonists for p56lck SH2 domain.

Journal: Bioorganic & medicinal chemistry 20070601

Title: An ectophosphatase activity in Candida parapsilosis influences the interaction of fungi with epithelial cells.

Journal: FEMS yeast research 20070601

Title: Not so simple: the complexity of phosphotyrosine signaling at cadherin adhesive contacts.

Journal: Journal of molecular medicine (Berlin, Germany) 20070601

Title: Localized activation of Src-family protein kinases in the mouse egg.

Journal: Developmental biology 20070601

Title: Structural and energetic aspects of Grb2-SH2 domain-swapping.

Journal: Archives of biochemistry and biophysics 20070601

Title: Structure of the PTB domain of tensin1 and a model for its recruitment to fibrillar adhesions.

Journal: Protein science : a publication of the Protein Society 20070601

Title: TccP2-mediated subversion of actin dynamics by EPEC 2 - a distinct evolutionary lineage of enteropathogenic Escherichia coli.

Journal: Microbiology (Reading, England) 20070601

Title: Cell surface receptors for signal transduction and ligand transport: a design principles study.

Journal: PLoS computational biology 20070601

Title: Effects of PPAR-gamma knock-down and hyperglycemia on insulin signaling in vascular smooth muscle cells from hypertensive rats.

Journal: Journal of cardiovascular pharmacology 20070601

Title: Is the c-Cbl proto-oncogene involved in chronic lymphocytic leukemia?

Journal: Annals of the New York Academy of Sciences 20070601

Title: Cetuximab in the management of colorectal cancer.

Journal: Biologics : targets & therapy 20070601

Title: A multiplexed protein kinase assay.

Journal: Chembiochem : a European journal of chemical biology 20070525

Title: Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases.

Journal: Nature 20070524

Title: A molecular dynamics study of WPD-loop flexibility in PTP1B.

Journal: Biochemical and biophysical research communications 20070518

Title: TCRzetadim lymphocytes define populations of circulating effector cells that migrate to inflamed tissues.

Journal: Blood 20070515

Title: A remote substrate docking mechanism for the tec family tyrosine kinases.

Journal: Biochemistry 20070508

Title: Development of molecular probes for second-site screening and design of protein tyrosine phosphatase inhibitors.

Journal: Journal of medicinal chemistry 20070503

Title: The role of ghrelin and some intracellular mechanisms in controlling the secretory activity of chicken ovarian cells.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20070501

Title: Identification and distribution of a novel platelet-derived growth factor receptor beta variant: effect of retinoic acid and involvement in cell differentiation.

Journal: Endocrinology 20070501

Title: Domains necessary for Galpha12 binding and stimulation of protein phosphatase-2A (PP2A): Is Galpha12 a novel regulatory subunit of PP2A?

Journal: Molecular pharmacology 20070501

Title: Localization and regulation of plasma membrane Ca(2+)-ATPase in bovine spermatozoa.

Journal: European journal of cell biology 20070501

Title: Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region.

Journal: European journal of immunology 20070501

Title: Molecular mechanisms of the diabetogenic effects of arsenic: inhibition of insulin signaling by arsenite and methylarsonous acid.

Journal: Environmental health perspectives 20070501

Title: CD99 activates T cells via a costimulatory function that promotes raft association of TCR complex and tyrosine phosphorylation of TCR zeta.

Journal: Experimental & molecular medicine 20070430

Title: Hierarchical disabled-1 tyrosine phosphorylation in Src family kinase activation and neurite formation.

Journal: Journal of molecular biology 20070427

Title: Structural studies of E. coli topoisomerase III-DNA complexes reveal a novel type IA topoisomerase-DNA conformational intermediate.

Journal: Journal of molecular biology 20070420

Title: Examination of acylated 4-aminopiperidine-4-carboxylic acid residues in the phosphotyrosyl+1 position of Grb2 SH2 domain-binding tripeptides.

Journal: Journal of medicinal chemistry 20070419

Title: Regulation of Arf6 and ACAP1 signaling by the PTB-domain-containing adaptor protein GULP.

Journal: Current biology : CB 20070417

Title: Paxillin family members function as Csk-binding proteins that regulate Lyn activity in human and murine platelets.

Journal: The Biochemical journal 20070415

Title: Imatinib increases the intracellular concentration of nilotinib, which may explain the observed synergy between these drugs.

Journal: Blood 20070415

Title: The receptor tyrosine kinase EphB4 is overexpressed in ovarian cancer, provides survival signals and predicts poor outcome.

Journal: British journal of cancer 20070410

Title: The role of presenilin and its interacting proteins in the biogenesis of Alzheimer's beta amyloid.

Journal: Neurochemical research 20070401

Title: Association of protein kinase C-delta with the B cell antigen receptor complex.

Journal: Cellular signalling 20070401

Title: Entamoeba histolytica: an ecto-phosphatase activity regulated by oxidation-reduction reactions.

Journal: Experimental parasitology 20070401

Title: A proteomic approach to the investigation of early events involved in vascular smooth muscle cell activation.

Journal: Cell and tissue research 20070401

Title: CCK causes PKD1 activation in pancreatic acini by signaling through PKC-delta and PKC-independent pathways.

Journal: Biochimica et biophysica acta 20070401

Title: FGFR3 intracellular mutations induce tyrosine phosphorylation in the Golgi and defective glycosylation.

Journal: Biochimica et biophysica acta 20070401

Title: Cdk5 is involved in BDNF-stimulated dendritic growth in hippocampal neurons.

Journal: PLoS biology 20070401

Title: Regulation of B-lymphocyte activation by the PH domain adaptor protein Bam32/DAPP1.

Journal: Biochemical Society transactions 20070401

Title: Phosphotyrosine/phosphoserine binary switches: a new paradigm for the regulation of PI3K signalling and growth factor pleiotropy?

Journal: Biochemical Society transactions 20070401

Title: High expression of several tyrosine kinases and activation of the PI3K/AKT pathway in mediastinal large B cell lymphoma reveals further similarities to Hodgkin lymphoma.

Journal: Leukemia 20070401

Title: Evaluation of enrichment techniques for mass spectrometry: identification of tyrosine phosphoproteins in cancer cells.

Journal: The Journal of molecular diagnostics : JMD 20070401

Title: Dasatinib (BMS-354825) inhibits Stat5 signaling associated with apoptosis in chronic myelogenous leukemia cells.

Journal: Molecular cancer therapeutics 20070401

Title: Structural basis for selective inhibition of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB.

Journal: Structure (London, England : 1993) 20070401

Title: Asymmetric synthesis of the (S)-1,1-dioxido-isothiazolidin-3-one phosphotyrosine mimetic via reduction of a homochiral (R)-oxido-isothiazolidin-3-one.

Journal: Organic letters 20070329

Title: Src family kinases mediate neutrophil adhesion to adherent platelets.

Journal: Blood 20070315

Title: c-Src activates endonuclease-mediated mRNA decay.

Journal: Molecular cell 20070309

Title: Cordycepin (3'-deoxyadenosine) inhibits human platelet aggregation in a cyclic AMP- and cyclic GMP-dependent manner.

Journal: European journal of pharmacology 20070308

Title: ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells.

Journal: Blood 20070301

Title: Beneficial effects of combining nilotinib and imatinib in preclinical models of BCR-ABL+ leukemias.

Journal: Blood 20070301

Title: Acute impairment of insulin signalling by dexamethasone in primary cultured rat skeletal myocytes.

Journal: Molecular and cellular biochemistry 20070301

Title: Cr(VI)-stimulated STAT3 tyrosine phosphorylation and nuclear translocation in human airway epithelial cells requires Lck.

Journal: The Biochemical journal 20070301

Title: Acetaldehyde dissociates the PTP1B-E-cadherin-beta-catenin complex in Caco-2 cell monolayers by a phosphorylation-dependent mechanism.

Journal: The Biochemical journal 20070301

Title: Suppression effect of seminal vesicle autoantigen on platelet-activating factor-induced mouse sperm capacitation.

Journal: Journal of cellular biochemistry 20070301

Title: Enzyme-substrate interactions revealed by the crystal structures of the archaeal Sulfolobus PTP-fold phosphatase and its phosphopeptide complexes.

Journal: Proteins 20070301

Title: Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells.

Journal: Molecular immunology 20070301

Title: Two axes in platelet-derived growth factor signaling: tyrosine phosphorylation and reactive oxygen species.

Journal: Cellular and molecular life sciences : CMLS 20070301

Title: Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD.

Journal: Leukemia 20070301

Title: Semisynthesis of unnatural amino acid mutants of paxillin: protein probes for cell migration studies.

Journal: Protein science : a publication of the Protein Society 20070301

Title: Phosphoproteomic analysis identifies the M0-91 cell line as a cellular model for the study of TEL-TRKC fusion-associated leukemia.

Journal: Leukemia 20070301

Title: Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility.

Journal: Nature structural & molecular biology 20070301

Title: MAPK phosphatases--regulating the immune response.

Journal: Nature reviews. Immunology 20070301

Title: Exploring DNA topoisomerases as targets of novel therapeutic agents in the treatment of infectious diseases.

Journal: Infectious disorders drug targets 20070301

Title: Src family kinase activity regulates adhesion, spreading and migration of pancreatic endocrine tumour cells.

Journal: Endocrine-related cancer 20070301

Title: Gefitinib-sensitive EGFR lacking residues 746-750 exhibits hypophosphorylation at tyrosine residue 1045, hypoubiquitination, and impaired endocytosis.

Journal: DNA and cell biology 20070301

Title: Immunological outcomes of exercise in older adults.

Journal: Clinical interventions in aging 20070301

Title: Immunosupportive therapies in aging.

Journal: Clinical interventions in aging 20070301

Title: Cell death and cytotoxic effects in YAC-1 lymphoma cells following exposure to various forms of mercury.

Journal: Toxicology 20070227

Title: PMA activates Stat3 in the Jak/Stat pathway and induces SOCS5 in rat brain astrocytes.

Journal: Molecules and cells 20070227

Title: Src signaling regulates completion of abscission in cytokinesis through ERK/MAPK activation at the midbody.

Journal: The Journal of biological chemistry 20070223

Title: ALK activation induces Shc and FRS2 recruitment: Signaling and phenotypic outcomes in PC12 cells differentiation.

Journal: FEBS letters 20070220

Title: Reverse interactomics: from peptides to proteins and to functions.

Journal: ACS chemical biology 20070220

Title: The phosphothreonine lyase activity of a bacterial type III effector family.

Journal: Science (New York, N.Y.) 20070216

Title: Direct on-membrane peptide mass fingerprinting with MALDI-MS of tyrosine-phosphorylated proteins detected by immunostaining.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070215

Title: Gonadotropin-releasing hormone type II antagonists induce apoptotic cell death in human endometrial and ovarian cancer cells in vitro and in vivo.

Journal: Cancer research 20070215

Title: The structure of the minimal relaxase domain of MobA at 2.1 A resolution.

Journal: Journal of molecular biology 20070209

Title: Two tyrosine residues of Toll-like receptor 3 trigger different steps of NF-kappa B activation.

Journal: The Journal of biological chemistry 20070209

Title: Homogeneous time-resolved fluorescence assays for the detection of activity and inhibition of phosphatase enzymes employing phosphorescently labeled peptide substrates.

Journal: Analytica chimica acta 20070205

Title: How tyrosine 15 phosphorylation inhibits the activity of cyclin-dependent kinase 2-cyclin A.

Journal: The Journal of biological chemistry 20070202

Title: Src-family tyrosine kinase fyn phosphorylates phosphatidylinositol 3-kinase enhancer-activating Akt, preventing its apoptotic cleavage and promoting cell survival.

Journal: Cell death and differentiation 20070201

Title: BCL-2 expression is mainly regulated by JAK/STAT3 pathway in human CD34+ hematopoietic cells.

Journal: Cell death and differentiation 20070201

Title: c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070201

Title: Trophoblast adhesion of the peri-implantation mouse blastocyst is regulated by integrin signaling that targets phospholipase C.

Journal: Developmental biology 20070201

Title: Late signaling in the activated platelets upregulates tyrosine phosphatase SHP1 and impairs platelet adhesive functions: Regulation by calcium and Src kinase.

Journal: Biochimica et biophysica acta 20070201

Title: Activation of human T lymphocytes via integrin signaling induced by RGD-disintegrins.

Journal: Biochimica et biophysica acta 20070201

Title: Phosphorylation-dependent metal binding by alpha-synuclein peptide fragments.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070201

Title: Identification of the ligands of protein interaction domains through a functional approach.

Journal: Molecular & cellular proteomics : MCP 20070201

Title: Apoptosis induced by crocidolite asbestos in human lung epithelial cells involves inactivation of Akt and MAPK pathways.

Journal: Apoptosis : an international journal on programmed cell death 20070201

Title: Lysophosphatidic acid promoting corneal epithelial wound healing by transactivation of epidermal growth factor receptor.

Journal: Investigative ophthalmology & visual science 20070201

Title: Proteomic analysis of tyrosine phosphorylations in vascular endothelial growth factor- and reactive oxygen species-mediated signaling pathway.

Journal: Journal of proteome research 20070201

Title: Quantitative proteomic approaches for studying phosphotyrosine signaling.

Journal: Expert review of proteomics 20070201

Title: Interaction between krit1 and malcavernin: implications for the pathogenesis of cerebral cavernous malformations.

Journal: Neurosurgery 20070201

Title: Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function.

Journal: PLoS biology 20070201

Title: Identification of a potential general acid/base in the reversible phosphoryl transfer reactions catalyzed by tyrosine recombinases: Flp H305.

Journal: Chemistry & biology 20070201

Title: AP20187-mediated activation of a chimeric insulin receptor results in insulin-like actions in skeletal muscle and liver of diabetic mice.

Journal: Human gene therapy 20070201

Title: Platelets possess functional TGF-beta receptors and Smad2 protein.

Journal: Platelets 20070201

Title: PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration.

Journal: Current biology : CB 20070123

Title: Utilization of achiral alkenyl amines for the preparation of high affinity Grb2 SH2 domain-binding macrocycles by ring-closing metathesis.

Journal: Organic & biomolecular chemistry 20070121

Title: Candidate gene polymorphisms in the serotonergic pathway: influence on depression symptomatology in an elderly population.

Journal: Biological psychiatry 20070115

Title: Redundancy in B cell developmental pathways: c-Cbl inactivation rescues early B cell development through a B cell linker protein-independent pathway.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20070115

Title: Identification of CXCL11 as a STAT3-dependent gene induced by IFN.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20070115

Title: The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export.

Journal: Genes & development 20070115

Title: Proliferation and apoptosis in PhIP-induced rat mammary gland carcinomas with elevated phosphotyrosine-STAT5a.

Journal: FEBS letters 20070109

Title: Halothane affects focal adhesion proteins in the A 549 cells.

Journal: Molecular and cellular biochemistry 20070101

Title: UNC-51-like kinase regulation of fibroblast growth factor receptor substrate 2/3.

Journal: Cellular signalling 20070101

Title: Focal adhesion signaling is required for myometrial ERK activation and contractile phenotype switch before labor.

Journal: Journal of cellular biochemistry 20070101

Title: Role of protein phosphatase 2A in calcium-dependent chloride secretion by human colonic epithelial cells.

Journal: American journal of physiology. Cell physiology 20070101

Title: Staurosporine induces tyrosine phosphorylation in Dictyostelium discoideum proteins.

Journal: Cell biochemistry and function 20070101

Title: An intracellular multi-effector complex mediates somatostatin receptor 1 activation of phospho-tyrosine phosphatase eta.

Journal: Molecular endocrinology (Baltimore, Md.) 20070101

Title: Crystal structure of human TMDP, a testis-specific dual specificity protein phosphatase: implications for substrate specificity.

Journal: Proteins 20070101

Title: Involvement of Src kinases and PLCgamma2 in clot retraction.

Journal: Thrombosis research 20070101

Title: Uteroglobin induces the development and cellular proliferation of the mouse early embryo.

Journal: Journal of experimental zoology. Part A, Ecological genetics and physiology 20070101

Title: Focus on phosphohistidine.

Journal: Amino acids 20070101

Title: Measurement of the formation of complexes in tyrosine kinase-mediated signal transduction.

Journal: Acta crystallographica. Section D, Biological crystallography 20070101

Title: The use of biophysical methods increases success in obtaining liganded crystal structures.

Journal: Acta crystallographica. Section D, Biological crystallography 20070101

Title: Enrichment of phosphotyrosine proteome of human platelets by immunoprecipitation.

Journal: Methods in molecular biology (Clifton, N.J.) 20070101

Title: The effects of lidocaine and bupivacaine on protein expression of cleaved caspase 3 and tyrosine phosphorylation in the rat hippocampal slice.

Journal: Anesthesia and analgesia 20070101

Title: Involvement of apolipoprotein E in excess fat accumulation and insulin resistance.

Journal: Diabetes 20070101

Title: Effects of seminal plasma on cooling-induced capacitative changes in boar sperm.

Journal: Journal of andrology 20070101

Title: Proteomic analysis of tyrosine phosphorylation during human liver transplantation.

Journal: Proteome science 20070101

Title: Modeling HER2 effects on cell behavior from mass spectrometry phosphotyrosine data.

Journal: PLoS computational biology 20070101

Title: Grb2-associated binder 1 polymorphism was associated with the risk of Helicobactor pylori infection and gastric atrophy.

Journal: International journal of medical sciences 20070101

Title: AYUMS: an algorithm for completely automatic quantitation based on LC-MS/MS proteome data and its application to the analysis of signal transduction.

Journal: BMC bioinformatics 20070101

Title: Sensitivity to pertuzumab (2C4) in ovarian cancer models: cross-talk with estrogen receptor signaling.

Journal: Molecular cancer therapeutics 20070101

Title: Quantitating peptide-protein interactions.

Journal: Journal of proteome research 20070101

Title: ArhGAP9, a novel MAP kinase docking protein, inhibits Erk and p38 activation through WW domain binding.

Journal: Journal of molecular signaling 20070101

Title: Caspase-dependent proteolytic cleavage of STAT3alpha in ES cells, in mammary glands undergoing forced involution and in breast cancer cell lines.

Journal: BMC cancer 20070101

Title: Cytokine responses of human lung cells (BEAS-2B) treated with micron-sized and nanoparticles of metal oxides compared to soil dusts.

Journal: Particle and fibre toxicology 20070101

Title: Role for non-proteolytic control of M-phase-promoting factor activity at M-phase exit.

Journal: PloS one 20070101

Title: The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription.

Journal: Annual review of biochemistry 20070101

Title: Differential response of lymphatic, venous and arterial endothelial cells to angiopoietin-1 and angiopoietin-2.

Journal: BMC cell biology 20070101

Title: Analysis of proteins binding to the ITAM motif of the beta-subunit of the high-affinity receptor for IgE (FcepsilonRI).

Journal: Journal of receptor and signal transduction research 20070101

Title: Breakage-reunion domain of Streptococcus pneumoniae topoisomerase IV: crystal structure of a gram-positive quinolone target.

Journal: PloS one 20070101

Title: Tyr66 acts as a conformational switch in the closed-to-open transition of the SHP-2 N-SH2-domain phosphotyrosine-peptide binding cleft.

Journal: BMC structural biology 20070101

Title: Control of PDGF-induced reactive oxygen species (ROS) generation and signal transduction in human lens epithelial cells.

Journal: Molecular vision 20070101

Title: [Role of c-Jun NH (2)-terminal kinase in insulin resistance after burn].

Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20070101

Title: Role of ubiquitination in IGF-1 receptor signaling and degradation.

Journal: PloS one 20070101

Title: Flexible mapping of homology onto structure with homolmapper.

Journal: BMC bioinformatics 20070101

Title: An insight into the sialome of the oriental rat flea, Xenopsylla cheopis (Rots).

Journal: BMC genomics 20070101

Title: Reversible protein tyrosine phosphorylation affects pollen germination and pollen tube growth via the actin cytoskeleton.

Journal: Protoplasma 20070101

Title: Genomic analysis of human lung fibroblasts exposed to vanadium pentoxide to identify candidate genes for occupational bronchitis.

Journal: Respiratory research 20070101

Title: Quantitative proteomic analysis of phosphotyrosine-mediated cellular signaling networks.

Journal: Methods in molecular biology (Clifton, N.J.) 20070101

Title: Chemoenzymatic enrichment of phosphotyrosine-containing peptides.

Journal: Angewandte Chemie (International ed. in English) 20070101

Title: STATc is a key regulator of the transcriptional response to hyperosmotic shock.

Journal: BMC genomics 20070101

Title: Functional and biological properties of the nuclear receptor coregulator PELP1/MNAR.

Journal: Nuclear receptor signaling 20070101

Title: Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer.

Journal: Breast cancer research : BCR 20070101

Title: Regulation of p73 by Hck through kinase-dependent and independent mechanisms.

Journal: BMC molecular biology 20070101

Title: Malarial pigment haemozoin, IFN-gamma, TNF-alpha, IL-1beta and LPS do not stimulate expression of inducible nitric oxide synthase and production of nitric oxide in immuno-purified human monocytes.

Journal: Malaria journal 20070101

Title: Mammalian sperm capacitation: role of phosphotyrosine proteins.

Journal: Society of Reproduction and Fertility supplement 20070101

Title: Cyclic AMP signalling pathways in the regulation of uterine relaxation.

Journal: BMC pregnancy and childbirth 20070101

Title: Evolutionary history and functional implications of protein domains and their combinations in eukaryotes.

Journal: Genome biology 20070101

Title: Neurite outgrowth on a fibronectin isoform expressed during peripheral nerve regeneration is mediated by the interaction of paxillin with alpha4beta1 integrins.

Journal: BMC neuroscience 20070101

Title: Tyrosine phosphatases such as SHP-2 act in a balance with Src-family kinases in stabilization of postsynaptic clusters of acetylcholine receptors.

Journal: BMC neuroscience 20070101

Title: B and T lymphocyte attenuator interacts with CD3zeta and inhibits tyrosine phosphorylation of TCRzeta complex during T-cell activation.

Journal: Immunology and cell biology 20070101

Title: Protein-tyrosine kinase activity profiling in knock down zebrafish embryos.

Journal: PloS one 20070101

Title: Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival.

Journal: Retrovirology 20070101

Title: Role of IRS and PHIP on insulin-induced tyrosine phosphorylation and distribution of IRS proteins.

Journal: Cell structure and function 20070101

Title: Altered T-cell function in schizophrenia: a cellular model to investigate molecular disease mechanisms.

Journal: PloS one 20070101

Title: Analysis of the Rana catesbeiana tadpole tail fin proteome and phosphoproteome during T3-induced apoptosis: identification of a novel type I keratin.

Journal: BMC developmental biology 20070101

Title: Heregulin beta1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells.

Journal: Breast cancer research : BCR 20070101

Title: UDP-acetyl-mannosamine dehydrogenase is an endogenous protein substrate of Staphylococcus aureus protein-tyrosine kinase activity.

Journal: Journal of molecular microbiology and biotechnology 20070101

Title: MOZ-TIF2 repression of nuclear receptor-mediated transcription requires multiple domains in MOZ and in the CID domain of TIF2.

Journal: Molecular cancer 20070101

Title: Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein.

Journal: BMC cancer 20070101

Title: Microbial proteomics: a mass spectrometry primer for biologists.

Journal: Microbial cell factories 20070101

Title: Multiple domain insertions and losses in the evolution of the Rab prenylation complex.

Journal: BMC evolutionary biology 20070101

Title: A microarray strategy for mapping the substrate specificity of protein tyrosine phosphatase.

Journal: Angewandte Chemie (International ed. in English) 20070101

Title: Fc gamma RII activation induces cell surface ceramide production which participates in the assembly of the receptor signaling complex.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

Title: Neuregulin3 alters cell fate in the epidermis and mammary gland.

Journal: BMC developmental biology 20070101

Title: Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation.

Journal: BMC structural biology 20070101

Title: Developmental expression and differentiation-related neuron-specific splicing of metastasis suppressor 1 (Mtss1) in normal and transformed cerebellar cells.

Journal: BMC developmental biology 20070101

Title: Nilotinib treatment in mouse models of P190 Bcr/Abl lymphoblastic leukemia.

Journal: Molecular cancer 20070101

Title: Increased T-cell reactivity and elevated levels of CD8+ memory T-cells in Alzheimer's disease-patients and T-cell hyporeactivity in an Alzheimer's disease-mouse model: implications for immunotherapy.

Journal: Neuromolecular medicine 20070101

Title: [Growth factors of the EGF family and their receptors].

Journal: Bulletin du cancer 20070101

Title: Mechanism of homocysteine-induced Rac1/NADPH oxidase activation in mesangial cells: role of guanine nucleotide exchange factor Vav2.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

Title: Activation of FAK/PI3K/Rac1 signaling controls actin reorganization and inhibits cell motility in human cancer cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

Title: Syk-mediated translocation of PI3Kdelta to the leading edge controls lamellipodium formation and migration of leukocytes.

Journal: PloS one 20070101

Title: Dermal fibroblasts derived from fetal and postnatal humans exhibit distinct responses to insulin like growth factors.

Journal: BMC developmental biology 20070101

Title: UV-B-induced signaling events leading to enhanced-production of catharanthine in Catharanthus roseus cell suspension cultures.

Journal: BMC plant biology 20070101

Title: Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6.

Journal: Breast cancer research : BCR 20070101

Title: Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses.

Journal: Molecular systems biology 20070101

Title: Inhibition of cell motility by troglitazone in human ovarian carcinoma cell line.

Journal: BMC cancer 20070101

Title: HIV-1 Nef employs two distinct mechanisms to modulate Lck subcellular localization and TCR induced actin remodeling.

Journal: PloS one 20070101

Title: PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites.

Journal: Genome biology 20070101

Title: The TriTryp phosphatome: analysis of the protein phosphatase catalytic domains.

Journal: BMC genomics 20070101

Title: The Fer tyrosine kinase regulates an axon retraction response to Semaphorin 3A in dorsal root ganglion neurons.

Journal: BMC developmental biology 20070101

Title: Diversity and evolution of phycobilisomes in marine Synechococcus spp.: a comparative genomics study.

Journal: Genome biology 20070101

Title: Glutathione-S-transferase protects against oxidative injury of endothelial cell tight junctions.

Journal: Endothelium : journal of endothelial cell research 20070101

Title: Infection of mature dendritic cells with herpes simplex virus type 1 interferes with the interferon signaling pathway.

Journal: Immunobiology 20070101

Title: Stress preconditioning of spreading depression in the locust CNS.

Journal: PloS one 20070101

Title: Lipid rafts and caveolae in signaling by growth factor receptors.

Journal: The open biochemistry journal 20070101

Title: Protein Tyrosine Phosphatase Gamma (PTPgamma) is a Novel Leukocyte Marker Highly Expressed by CD34 Precursors.

Journal: Biomarker insights 20070101

Title: Computational systems biology in cancer: modeling methods and applications.

Journal: Gene regulation and systems biology 20070101

Title: Tyrosine phosphatase and cytochrome P450 activity are critical in regulating store-operated calcium channels in human fibroblasts.

Journal: Experimental & molecular medicine 20061231

Title: Using enzymatic reactions to enhance the photodynamic therapy effect of porphyrin dityrosine phosphates.

Journal: Chemical communications (Cambridge, England) 20061228

Title: Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia.

Journal: Blood 20061215

Title: Nuclear localization of PTEN is regulated by Ca(2+) through a tyrosil phosphorylation-independent conformational modification in major vault protein.

Journal: Cancer research 20061215

Title: Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain.

Journal: Genes & development 20061215

Title: p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration.

Journal: The EMBO journal 20061213

Title: Extracellular heat shock protein 70 mediates heat stress-induced epidermal growth factor receptor transactivation in A431 carcinoma cells.

Journal: FEBS letters 20061211

Title: Regulation of catalysis by the smallpox virus topoisomerase.

Journal: The Journal of biological chemistry 20061208

Title: Improvement of peripheral endothelial dysfunction by protein tyrosine phosphatase inhibitors in heart failure.

Journal: Circulation 20061205

Title: Leishmania amazonensis: characterization of an ecto-phosphatase activity.

Journal: Experimental parasitology 20061201

Title: RET oncoproteins induce tyrosine phosphorylation changes of proteins involved in RNA metabolism.

Journal: Cellular signalling 20061201

Title: TNF-alpha increases tyrosine phosphorylation of vascular endothelial cadherin and opens the paracellular pathway through fyn activation in human lung endothelia.

Journal: American journal of physiology. Lung cellular and molecular physiology 20061201

Title: Decreased protein tyrosine phosphorylation and membrane fluidity in spermatozoa from infertile men with varicocele.

Journal: Molecular reproduction and development 20061201

Title: Isolation and biochemical characteristics of a molecular form of epididymal acid phosphatase of boar seminal plasma.

Journal: Theriogenology 20061201

Title: Activated c-Fms recruits Vav and Rac during CSF-1-induced cytoskeletal remodeling and spreading in osteoclasts.

Journal: Bone 20061201

Title: Avian reovirus activates a novel proapoptotic signal by linking Src to p53.

Journal: Apoptosis : an international journal on programmed cell death 20061201

Title: Control of neuronal excitability by phosphorylation and dephosphorylation of sodium channels.

Journal: Biochemical Society transactions 20061201

Title: Identification and functional characterization of an Src homology domain 3 domain-binding site on Cbl.

Journal: The FEBS journal 20061201

Title: Hypoglycemic effects of vanadium on alloxan monohydrate induced diabetic dogs.

Journal: Journal of veterinary science 20061201

Title: Tyrosine phosphorylation controls PCNA function through protein stability.

Journal: Nature cell biology 20061201

Title: A role for p130Cas in mechanotransduction.

Journal: Cell 20061201

Title: Force sensing by mechanical extension of the Src family kinase substrate p130Cas.

Journal: Cell 20061201

Title: Activation of T lymphocytes and the role of the adapter LAT.

Journal: Transplant immunology 20061201

Title: Effect of glucocorticoid-induced osteoporotic-like conditions on osteoblast cell attachment to implant surface microtopographies.

Journal: Implant dentistry 20061201

Title: Alterations in protein tyrosine kinase pathways in rat liver following normothermic ischemia-reperfusion.

Journal: Transplantation proceedings 20061201

Title: Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.

Journal: PLoS medicine 20061201

Title: A new fragmentation rearrangement of the N-terminal protected amino acids using ESI-MS/MS.

Journal: Indian journal of biochemistry & biophysics 20061201

Title: [Amelioration of insulin resistance after scald by c-Jun N-terminal kinase inhibitor in rat].

Journal: Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20061201

Title: Role of erlotinib in the management of pancreatic cancer.

Journal: Therapeutics and clinical risk management 20061201

Title: Oxyhemoglobin-induced suppression of voltage-dependent K+ channels in cerebral arteries by enhanced tyrosine kinase activity.

Journal: Circulation research 20061124

Title: Brain-derived neurotrophic factor rapidly increases NMDA receptor channel activity through Fyn-mediated phosphorylation.

Journal: Brain research 20061122

Title: DAB1 and Reelin effects on amyloid precursor protein and ApoE receptor 2 trafficking and processing.

Journal: The Journal of biological chemistry 20061117

Title: SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20061115

Title: Conditional deletion of Shp2 in the mammary gland leads to impaired lobulo-alveolar outgrowth and attenuated Stat5 activation.

Journal: The Journal of biological chemistry 20061110

Title: Shift syndecan-2 from RACK1 to caveolin-2 upon transformation with oncogenic ras.

Journal: Biochemical and biophysical research communications 20061110

Title: Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells.

Journal: British journal of cancer 20061106

Title: Elevated activity of STAT3C due to higher DNA binding affinity of phosphotyrosine dimer rather than covalent dimer formation.

Journal: The Journal of biological chemistry 20061103

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

Journal: Cell 20061103

Title: Clinically relevant doses of fluoxetine and reboxetine induce changes in the TrkB content of central excitatory synapses.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20061101

Title: Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells.

Journal: American journal of physiology. Endocrinology and metabolism 20061101

Title: Insulin-like growth factor-I induces alpha(1B)-adrenergic receptor phosphorylation through G beta gamma and epidermal growth factor receptor transactivation.

Journal: Molecular endocrinology (Baltimore, Md.) 20061101

Title: Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis.

Journal: American journal of physiology. Cell physiology 20061101

Title: Impaired neutrophil chemotaxis in sepsis associates with GRK expression and inhibition of actin assembly and tyrosine phosphorylation.

Journal: Blood 20061101

Title: A new marine-derived sulfated polysaccharide from brown alga suppresses tumor metastasis both in vitro and in vivo.

Journal: Cancer biology & therapy 20061101

Title: Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils.

Journal: Nature cell biology 20061101

Title: Characterization of ecto-phosphatase activities of Trypanosoma cruzi: a comparative study between Colombiana and Y strains.

Journal: Acta tropica 20061101

Title: Receptor cross-linking on human plasmacytoid dendritic cells leads to the regulation of IFN-alpha production.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20061101

Title: Cbl-b is a negative regulator of inflammatory cytokines produced by IgE-activated mast cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20061101

Title: Optimization of the cellular import of functionally active SH2-domain-interacting phosphopeptides.

Journal: Cellular and molecular life sciences : CMLS 20061101

Title: Human cationic trypsinogen is sulfated on Tyr154.

Journal: The FEBS journal 20061101

Title: Cardiovascular effects of nickel in ambient air.

Journal: Environmental health perspectives 20061101

Title: Enhancement of insulin signaling pathway in adipocytes by oxovanadium(IV) complexes.

Journal: Biochemical and biophysical research communications 20061027

Title: Csk-binding protein mediates sequential enzymatic down-regulation and degradation of Lyn in erythropoietin-stimulated cells.

Journal: The Journal of biological chemistry 20061020

Title: Structure-based design of potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics.

Journal: Biochemical and biophysical research communications 20061020

Title: Unique role of SNT-2/FRS2beta/FRS3 docking/adaptor protein for negative regulation in EGF receptor tyrosine kinase signaling pathways.

Journal: Oncogene 20061019

Title: High-throughput kinase assay based on surface plasmon resonance suitable for native protein substrates.

Journal: Analytical biochemistry 20061015

Title: In situ phosphorylation of immobilized receptors on biosensor surfaces: application to E-cadherin/beta-catenin interactions.

Journal: Analytical biochemistry 20061015

Title: ReSETting PP2A tumour suppressor activity in blast crisis and imatinib-resistant chronic myelogenous leukaemia.

Journal: British journal of cancer 20061009

Title: Engineering the recruitment of phosphotyrosine binding domain-containing adaptor proteins reveals distinct roles for RET receptor-mediated cell survival.

Journal: The Journal of biological chemistry 20061006

Title: The tyrosine kinase c-Abl protects c-Jun from ubiquitination-mediated degradation in T cells.

Journal: The Journal of biological chemistry 20061006

Title: Action of TFII-I outside the nucleus as an inhibitor of agonist-induced calcium entry.

Journal: Science (New York, N.Y.) 20061006

Title: Ligand-independent and EGF receptor-supported transactivation: lessons from beta2-adrenergic receptor signalling.

Journal: Cellular signalling 20061001

Title: Cell surface beta 1, 4-galactosyltransferase 1 promotes apoptosis by inhibiting epidermal growth factor receptor pathway.

Journal: Molecular and cellular biochemistry 20061001

Title: Focal adhesion and actin organization by a cross-talk of TM4SF5 with integrin alpha2 are regulated by serum treatment.

Journal: Experimental cell research 20061001

Title: Fibroblast growth factor-2 induces the activation of Src through Fes, which regulates focal adhesion disassembly.

Journal: Experimental cell research 20061001

Title: A global proteomics approach identifies novel phosphorylated signaling proteins in GPVI-activated platelets: involvement of G6f, a novel platelet Grb2-binding membrane adapter.

Journal: Proteomics 20061001

Title: Focal adhesion kinase signaling at sites of integrin-mediated adhesion controls axon pathfinding.

Journal: Nature neuroscience 20061001

Title: Hypophosphorylation of residue Y1045 leads to defective downregulation of EGFRvIII.

Journal: Cancer biology & therapy 20061001

Title: Dynamic quantification of the tyrosine phosphorylation of the sperm surface proteins during capacitation.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20061001

Title: Thrombin induces GPIb-IX-mediated fibrin binding to alphaIIbbeta3 in a reconstituted Chinese hamster ovary cell model.

Journal: Journal of thrombosis and haemostasis : JTH 20061001

Title: Role of Rac1 in fibronectin-induced adhesion and motility of human corneal epithelial cells.

Journal: Investigative ophthalmology & visual science 20061001

Title: Effect of five triterpenoid compounds from the buds of Aralia elata on stimulus-induced superoxide generation, tyrosyl phosphorylation and translocation of cytosolic compounds to the cell membrane in human neutrophils.

Journal: Planta medica 20061001

Title: Phosphotyrosine signaling in platelets: lessons for vascular thrombosis.

Journal: Current drug targets 20061001

Title: CD45 isoform expression in microglia and inflammatory cells in HIV-1 encephalitis.

Journal: Brain pathology (Zurich, Switzerland) 20061001

Title: Expression of the SNT-1/FRS2 phosphotyrosine binding domain inhibits activation of MAP kinase and PI3-kinase pathways and antiestrogen resistant growth induced by FGF-1 in human breast carcinoma cells.

Journal: Oncogene 20060928

Title: Involvement of insulin-like growth factor type 1 receptor and protein kinase Cdelta in bis(maltolato)oxovanadium(IV)-induced phosphorylation of protein kinase B in HepG2 cells.

Journal: Biochemistry 20060926

Title: Synthetic D-amino acid peptide inhibits tumor cell motility on laminin-5.

Journal: Carcinogenesis 20060901

Title: Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane.

Journal: Journal of cellular physiology 20060901

Title: Isothiazolidinone heterocycles as inhibitors of protein tyrosine phosphatases: synthesis and structure-activity relationships of a peptide scaffold.

Journal: Bioorganic & medicinal chemistry 20060901

Title: Hexose-specificity of hexokinase and ADP-dependence of pyruvate kinase play important roles in the control of monosaccharide utilization in freshly diluted boar spermatozoa.

Journal: Molecular reproduction and development 20060901

Title: Identification and characterization of NYGGF4, a novel gene containing a phosphotyrosine-binding (PTB) domain that stimulates 3T3-L1 preadipocytes proliferation.

Journal: Gene 20060901

Title: Chromium and vanadate combination increases insulin-induced glucose uptake by 3T3-L1 adipocytes.

Journal: Biochemical and biophysical research communications 20060901

Title: Binding of sialyl Lewis X antigen to lectin-like receptors on NK cells induces cytotoxicity and tyrosine phosphorylation of a 17-kDa protein.

Journal: Biochimica et biophysica acta 20060901

Title: Photoreceptor morphogenesis in the Drosophila compound eye: R1-R6 rhabdomeres become twisted just before eclosion.

Journal: The Journal of comparative neurology 20060901

Title: Sodium orthovanadate induced tyrosine phosphorylation of platelet nitric oxide synthase negatively regulates enzyme activity.

Journal: Biochimica et biophysica acta 20060901

Title: Identification of a tyrosine-phosphorylated CCCTC-binding nuclear factor in capacitated mouse spermatozoa.

Journal: Proteomics 20060901

Title: Cool-1 functions as an essential regulatory node for EGF receptor- and Src-mediated cell growth.

Journal: Nature cell biology 20060901

Title: Molecular and functional characterization of CD300b, a new activating immunoglobulin receptor able to transduce signals through two different pathways.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20060901

Title: Mutational analysis of the mechanism of negative regulation by SRC homology 2 domain-containing protein tyrosine phosphatase substrate-1 of phagocytosis in macrophages.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20060901

Title: Characterization of a tyrosine phosphatase activity in the oogenesis of Periplaneta americana.

Journal: Archives of insect biochemistry and physiology 20060901

Title: Identification of radiation-induced cross-linking between thymine and tryptophan by electrospray ionization-mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20060901

Title: Quantitative multiplexed profiling of cellular signaling networks using phosphotyrosine-specific DNA-tagged SH2 domains.

Journal: Nature methods 20060901

Title: Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote.

Journal: PLoS biology 20060901

Title: Crystallization and preliminary X-ray diffraction analysis of rat protein tyrosine phosphatase eta.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20060901

Title: Solution structure and phosphopeptide binding of the SH2 domain from the human Bruton's tyrosine kinase.

Journal: Journal of biomolecular NMR 20060901

Title: Integration of P2Y receptor-activated signal transduction pathways in G protein-dependent signalling networks.

Journal: Purinergic signalling 20060901

Title: A cationic lanthanide complex binds selectively to phosphorylated tyrosine sites, aiding NMR analysis of the phosphorylated insulin receptor peptide fragment.

Journal: Organic & biomolecular chemistry 20060821

Title: Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.

Journal: Bioorganic & medicinal chemistry letters 20060815

Title: Structural basis for phosphotyrosine recognition by the Src homology-2 domains of the adapter proteins SH2-B and APS.

Journal: Journal of molecular biology 20060804

Title: Lck couples Shc to TCR signaling.

Journal: Cellular signalling 20060801

Title: Activation of Epstein-Barr virus/C3d receptor (gp140, CR2, CD21) on human B lymphoma cell surface triggers Cbl tyrosine phosphorylation, its association with p85 subunit, Crk-L and Syk and its dissociation with Vav.

Journal: Cellular signalling 20060801

Title: Regulation of Stat3 nuclear import by importin alpha5 and importin alpha7 via two different functional sequence elements.

Journal: Cellular signalling 20060801

Title: Phosphoregulation of signal transduction pathways in ischemia and reperfusion.

Journal: The Journal of surgical research 20060801

Title: Bifunctional role of the leishmanial antimonate reductase LmACR2 as a protein tyrosine phosphatase.

Journal: Molecular and biochemical parasitology 20060801

Title: Functional proteomics identifies protein-tyrosine phosphatase 1B as a target of RhoA signaling.

Journal: Molecular & cellular proteomics : MCP 20060801

Title: Dynamics of the WPD loop of the Yersinia protein tyrosine phosphatase.

Journal: Biophysical journal 20060801

Title: 15-Deoxy-delta12,14-prostaglandin J2 regulates leukemia inhibitory factor signaling through JAK-STAT pathway in mouse embryonic stem cells.

Journal: Experimental cell research 20060801

Title: Angiotensin II type 2 receptor-bradykinin B2 receptor functional heterodimerization.

Journal: Hypertension (Dallas, Tex. : 1979) 20060801

Title: Signal transduction in endothelial cells by the angiogenesis inhibitor histidine-rich glycoprotein targets focal adhesions.

Journal: Experimental cell research 20060801

Title: Downregulation of the PI3K/Akt survival pathway in cells with deregulated expression of c-Myc.

Journal: Apoptosis : an international journal on programmed cell death 20060801

Title: Membrane and juxtamembrane targeting by PH and PTB domains.

Journal: Biochimica et biophysica acta 20060801

Title: Low-molecular-weight chromium-binding substance from chicken liver and American alligator liver.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20060801

Title: The Rap GTPases mediate CXCL13- and sphingosine1-phosphate-induced chemotaxis, adhesion, and Pyk2 tyrosine phosphorylation in B lymphocytes.

Journal: European journal of immunology 20060801

Title: Profilin tyrosine phosphorylation in poly-L-proline-binding regions inhibits binding to phosphoinositide 3-kinase in Phaseolus vulgaris.

Journal: The Plant journal : for cell and molecular biology 20060801

Title: Negative regulation of ERK activity by VRK3-mediated activation of VHR phosphatase.

Journal: Nature cell biology 20060801

Title: New prospects for an old enzyme: mammalian cytochrome c is tyrosine-phosphorylated in vivo.

Journal: Biochemistry 20060801

Title: Temporal dynamics of tyrosine phosphorylation in insulin signaling.

Journal: Diabetes 20060801

Title: A pseudosymmetric cell adhesion regulatory domain in the beta7 tail of the integrin alpha4beta7 that interacts with focal adhesion kinase and src.

Journal: European journal of immunology 20060801

Title: Phosphopeptide ligands of the SHP-1 N-SH2 domain: effects on binding and stimulation of phosphatase activity.

Journal: ChemMedChem 20060801

Title: Structural basis for phosphotyrosine recognition by suppressor of cytokine signaling-3.

Journal: Structure (London, England : 1993) 20060801

Title: Structure and mechanism of the phosphotyrosyl phosphatase activator.

Journal: Molecular cell 20060801

Title: CXCR4 physically associates with the T cell receptor to signal in T cells.

Journal: Immunity 20060801

Title: Endogenously generated reactive oxygen species reduce PMCA activity in platelets from patients with non-insulin-dependent diabetes mellitus.

Journal: Platelets 20060801

Title: Nucleoside diphosphate kinase A as a controller of AMP-kinase in airway epithelia.

Journal: Journal of bioenergetics and biomembranes 20060801

Title: Differential effects of flavonoids on bovine kidney low molecular mass protein tyrosine phosphatase.

Journal: Journal of enzyme inhibition and medicinal chemistry 20060801

Title: Defective T cell receptor-mediated signal transduction in memory CD4 T lymphocytes exposed to superantigen or anti-T cell receptor antibodies.

Journal: Cellular immunology 20060801

Title: Blue native polyacrylamide gel electrophoresis (BN-PAGE) for the identification and analysis of multiprotein complexes.

Journal: Science's STKE : signal transduction knowledge environment 20060725

Title: Facile synthesis and application of uniformly 13C, 15N-labeled phosphotyrosine for ligand binding studies.

Journal: Bioorganic & medicinal chemistry letters 20060715

Title: Involvement of the N-terminal unique domain of Chk tyrosine kinase in Chk-induced tyrosine phosphorylation in the nucleus.

Journal: Experimental cell research 20060715

Title: Association of Grb-2 and PI3K p85 with phosphotyrosile peptides derived from BTLA.

Journal: Biochemical and biophysical research communications 20060714

Title: Identification of phosphoproteins associated with maintenance of transformed state in temperature-sensitive Rous sarcoma-virus infected cells by proteomic analysis.

Journal: Biochemical and biophysical research communications 20060707

Title: Src family tyrosine kinases differentially modulate exocytosis from rat brain nerve terminals.

Journal: Neurochemistry international 20060701

Title: Continuous assay of protein tyrosine phosphatases based on fluorescence resonance energy transfer.

Journal: Biochimie 20060701

Title: B cell antigen receptor signaling and internalization are mutually exclusive events.

Journal: PLoS biology 20060701

Title: Tyrosine phosphorylated proteins in the reproductive tract of the viviparous lizard Eulamprus tympanum and the oviparous lizard Lampropholis guichenoti.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20060701

Title: SRC-family tyrosine kinases in wound- and ligand-induced epidermal growth factor receptor activation in human corneal epithelial cells.

Journal: Investigative ophthalmology & visual science 20060701

Title: VEGF expression and receptor activation in the choroid during development and in the adult.

Journal: Investigative ophthalmology & visual science 20060701

Title: Two membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signaling.

Journal: PLoS genetics 20060701

Title: Macrophage pro-inflammatory response to Francisella novicida infection is regulated by SHIP.

Journal: PLoS pathogens 20060701

Title: [Detection of phosphotyrosine in bcr-abl-positive cells with PY20 antibody and its clinical applications].

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20060701

Title: The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.

Journal: The Journal of biological chemistry 20060630

Title: Potent benzimidazole sulfonamide protein tyrosine phosphatase 1B inhibitors containing the heterocyclic (S)-isothiazolidinone phosphotyrosine mimetic.

Journal: Journal of medicinal chemistry 20060629

Title: The human and mouse complement of SH2 domain proteins-establishing the boundaries of phosphotyrosine signaling.

Journal: Molecular cell 20060623

Title: NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity.

Journal: The EMBO journal 20060621

Title: Conformational analysis of gamma' peptide (410-427) interactions with thrombin anion binding exosite II.

Journal: Biochemistry 20060620

Title: A loss of c-kit expression is associated with an advanced stage and poor prognosis in breast cancer.

Journal: British journal of cancer 20060619

Title: A common phosphotyrosine signature for the Bcr-Abl kinase.

Journal: Blood 20060615

Title: Crotoxin induces actin reorganization and inhibits tyrosine phosphorylation and activity of small GTPases in rat macrophages.

Journal: Toxicon : official journal of the International Society on Toxinology 20060615

Title: The relation between survival and expression of HER1 and HER2 depends on the expression of HER3 and HER4: a study in bladder cancer patients.

Journal: British journal of cancer 20060605

Title: Vascular endothelial growth factor receptor-1 mediates migration of human colorectal carcinoma cells by activation of Src family kinases.

Journal: British journal of cancer 20060605

Title: Collagen type I selectively activates ectodomain shedding of the discoidin domain receptor 1: involvement of Src tyrosine kinase.

Journal: Journal of cellular biochemistry 20060601

Title: Adhesion and proliferation of fibroblasts on RF plasma-deposited nanostructured fluorocarbon coatings: evidence of FAK activation.

Journal: Journal of cellular physiology 20060601

Title: Effects of seawater pollutants on protein tyrosine phosphorylation in mussel tissues.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20060601

Title: Quinolinic acid modulates the activity of src family kinases in rat striatum: in vivo and in vitro studies.

Journal: Journal of neurochemistry 20060601

Title: Eph receptors are negatively controlled by protein tyrosine phosphatase receptor type O.

Journal: Nature neuroscience 20060601

Title: The enteropathogenic Escherichia coli EspF effector molecule inhibits PI-3 kinase-mediated uptake independently of mitochondrial targeting.

Journal: Cellular microbiology 20060601

Title: Activation of p38 mitogen-activated protein kinase promotes epidermal growth factor receptor internalization.

Journal: Traffic (Copenhagen, Denmark) 20060601

Title: Structure of human DSP18, a member of the dual-specificity protein tyrosine phosphatase family.

Journal: Acta crystallographica. Section D, Biological crystallography 20060601

Title: B and T lymphocyte attenuator-mediated signal transduction provides a potent inhibitory signal to primary human CD4 T cells that can be initiated by multiple phosphotyrosine motifs.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20060601

Title: Design and synthesis of phosphotyrosine peptidomimetic prodrugs.

Journal: Journal of medicinal chemistry 20060601

Title: The larval development of the telotrophic meroistic ovary in the bug Dysdercus intermedius (Heteroptera, Pyrrhocoridae).

Journal: Arthropod structure & development 20060601

Title: Structural basis for the phosphorylation-regulated focal adhesion targeting of type Igamma phosphatidylinositol phosphate kinase (PIPKIgamma) by talin.

Journal: Journal of molecular biology 20060526

Title: The elucidation of novel SH2 binding sites on PLD2.

Journal: Oncogene 20060518

Title: A kinase independent function for Tec kinase ITK in regulating antigen receptor induced serum response factor activation.

Journal: FEBS letters 20060515

Title: Increased Src kinase level results in increased protein tyrosine phosphorylation in scrapie-infected neuronal cell lines.

Journal: FEBS letters 20060515

Title: Major groove interactions of vaccinia Topo I provide specificity by optimally positioning the covalent phosphotyrosine linkage.

Journal: Biochemistry 20060509

Title: Tyrosine phosphorylation is required for functional activation of disulfide-containing constitutively active STAT mutants.

Journal: Biochemistry 20060502

Title: Lysophosphatidic acid-induced effects in human colon carcinoma DLD1 cells are partially dependent on transactivation of epidermal growth factor receptor.

Journal: The Journal of surgical research 20060501

Title: Sialylation regulates peripheral tolerance in CD4+ T cells.

Journal: International immunology 20060501

Title: Quantitative kinetic analysis of gene expression during human osteoblastic adhesion on orthopaedic materials.

Journal: Biomaterials 20060501

Title: Co-localization of cortactin and phosphotyrosine identifies active invadopodia in human breast cancer cells.

Journal: Experimental cell research 20060501

Title: Src homology 2 domain-based high throughput assays for profiling downstream molecules in receptor tyrosine kinase pathways.

Journal: Molecular & cellular proteomics : MCP 20060501

Title: The protein tyrosine phosphatase, Shp2, is required for the complete activation of the RAS/MAPK pathway by brain-derived neurotrophic factor.

Journal: Journal of neurochemistry 20060501

Title: Microfabricated discontinuous-edge surface topographies influence osteoblast adhesion, migration, cytoskeletal organization, and proliferation and enhance matrix and mineral deposition in vitro.

Journal: Calcified tissue international 20060501

Title: APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function.

Journal: Nature cell biology 20060501

Title: Doxycycline alters vascular smooth muscle cell adhesion, migration, and reorganization of fibrillar collagen matrices.

Journal: The American journal of pathology 20060501

Title: 2-D DIGE analysis of butyrate-treated HCT-116 cells after enrichment with heparin affinity chromatography.

Journal: Journal of proteome research 20060501

Title: Grasp a pTyr-peptide by its SOCS.

Journal: Developmental cell 20060501

Title: Formation of focal adhesion-like structures in circulating human neutrophils after severe injury: triggering of a tissue-phase response in the vascular space.

Journal: Shock (Augusta, Ga.) 20060501

Title: The leukocyte receptor complex in chicken is characterized by massive expansion and diversification of immunoglobulin-like Loci.

Journal: PLoS genetics 20060501

Title: Co expression of SCF and KIT in gastrointestinal stromal tumours (GISTs) suggests an autocrine/paracrine mechanism.

Journal: British journal of cancer 20060424

Title: Climbing the Greatwall to mitosis.

Journal: Molecular cell 20060421

Title: The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.

Journal: Molecular cell 20060421

Title: Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes.

Journal: Nature 20060406

Title: Dependence of tryptophan emission wavelength on conformation in cyclic hexapeptides.

Journal: The journal of physical chemistry. B 20060406

Title: Negative regulation of a protein tyrosine phosphatase by tyrosine phosphorylation.

Journal: Journal of the American Chemical Society 20060405

Title: Albumin induces cellular fibrosis by upregulating transforming growth factor-beta ligand and its receptors in renal distal tubule cells.

Journal: Journal of cellular biochemistry 20060401

Title: Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors.

Journal: Bioorganic & medicinal chemistry 20060401

Title: Oncogenic Met receptor induces cell-cycle progression in Xenopus oocytes independent of direct Grb2 and Shc binding or Mos synthesis, but requires phosphatidylinositol 3-kinase and Raf signaling.

Journal: Journal of cellular physiology 20060401

Title: Core erythropoietin receptor signals for late erythroblast development.

Journal: Blood 20060401

Title: Nitric oxide attenuates IGF-I-induced aortic smooth muscle cell motility by decreasing Rac1 activity: essential role of PTP-PEST and p130cas.

Journal: American journal of physiology. Cell physiology 20060401

Title: The molecular dynamics of osteoclast adhesions.

Journal: European journal of cell biology 20060401

Title: Blockade of interleukin-13-mediated cell activation by a novel inhibitory antibody to human IL-13 receptor alpha1.

Journal: Molecular immunology 20060401

Title: Reactive oxygen species generation is involved in epidermal growth factor receptor transactivation through the transient oxidization of Src homology 2-containing tyrosine phosphatase in endothelin-1 signaling pathway in rat cardiac fibroblasts.

Journal: Molecular pharmacology 20060401

Title: Tyrosine phosphorylation on capacitated human sperm tail detected by immunofluorescence correlates strongly with sperm-zona pellucida (ZP) binding but not with the ZP-induced acrosome reaction.

Journal: Human reproduction (Oxford, England) 20060401

Title: Prenatal MgSO4 treatment modifies the erythrocyte band 3 in preterm neonates.

Journal: Pharmacological research 20060401

Title: Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways.

Journal: Trends in cell biology 20060401

Title: Proteomic analysis reveals novel molecules involved in insulin signaling pathway.

Journal: Journal of proteome research 20060401

Title: Inhibition of phosphotyrosine phosphatase 1B causes resistance in BCR-ABL-positive leukemia cells to the ABL kinase inhibitor STI571.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060401

Title: Effect of brassinolide on tyrosine phosphorylation of pea leaf proteins.

Journal: Biochemistry. Biokhimiia 20060401

Title: Subcellular fractionation reveals proteins involved in insulin signaling.

Journal: Journal of proteome research 20060401

Title: Metallothionein antagonizes aging-induced cardiac contractile dysfunction: role of PTP1B, insulin receptor tyrosine phosphorylation and Akt.

Journal: Aging cell 20060401

Title: Altered expression, localization, and phosphorylation of epithelial junctional proteins in celiac disease.

Journal: American journal of clinical pathology 20060401

Title: Conformational changes in protein loops and helices induced by post-translational phosphorylation.

Journal: PLoS computational biology 20060401

Title: Evolution of cytokine responses: IL-1beta directly affects intracellular Ca2+ concentration of teleost fish leukocytes through a receptor-mediated mechanism.

Journal: Cytokine 20060401

Title: Identification of integrin alpha1 as an interacting protein of protein tyrosine phosphatase PRL-3.

Journal: Biochemical and biophysical research communications 20060331

Title: Alterations in intracellular calcium homeostasis and platelet aggregation induced by ethanol.

Journal: Biochemical and biophysical research communications 20060324

Title: Dimerization is required for SH3PX1 tyrosine phosphorylation in response to epidermal growth factor signalling and interaction with ACK2.

Journal: The Biochemical journal 20060315

Title: 1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20060315

Title: Pancreatitis-associated protein I suppresses NF-kappa B activation through a JAK/STAT-mediated mechanism in epithelial cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20060315

Title: JAK/STAT signal transduction: regulators and implication in hematological malignancies.

Journal: Biochemical pharmacology 20060314

Title: Crystal structure of the human B-form low molecular weight phosphotyrosyl phosphatase at 1.6-A resolution.

Journal: The Journal of biological chemistry 20060310

Title: A peroxisome proliferator-activated receptor-gamma agonist, troglitazone, facilitates caspase-8 and -9 activities by increasing the enzymatic activity of protein-tyrosine phosphatase-1B on human glioma cells.

Journal: The Journal of biological chemistry 20060310

Title: Structural basis for the requirement of two phosphotyrosine residues in signaling mediated by Syk tyrosine kinase.

Journal: Journal of molecular biology 20060310

Title: Discovery of a novel nonphosphorylated pentapeptide motif displaying high affinity for Grb2-SH2 domain by the utilization of 3'-substituted tyrosine derivatives.

Journal: Journal of medicinal chemistry 20060309

Title: Using a kinase/phosphatase switch to regulate a supramolecular hydrogel and forming the supramolecular hydrogel in vivo.

Journal: Journal of the American Chemical Society 20060308

Title: SOCS1 inhibits tumor necrosis factor-induced activation of ASK1-JNK inflammatory signaling by mediating ASK1 degradation.

Journal: The Journal of biological chemistry 20060303

Title: Chemical rescue of a mutant enzyme in living cells.

Journal: Science (New York, N.Y.) 20060303

Title: Her-2/neu and EGFR tyrosine kinase activation predict the efficacy of trastuzumab-based therapy in patients with metastatic breast cancer.

Journal: International journal of cancer 20060301

Title: Hyper-osmotic condition enhances protein tyrosine phosphorylation and zona pellucida binding capacity of human sperm.

Journal: Human reproduction (Oxford, England) 20060301

Title: In Saccharomyces cerevisiae an unbalanced level of tyrosine phosphorylation down-regulates the Ras/PKA pathway.

Journal: The international journal of biochemistry & cell biology 20060301

Title: Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans.

Journal: PLoS medicine 20060301

Title: The role of VEGF receptors in angiogenesis; complex partnerships.

Journal: Cellular and molecular life sciences : CMLS 20060301

Title: Molecular mapping of tyrosine-phosphorylated proteins in focal adhesions using fluorescence resonance energy transfer.

Journal: Journal of cell science 20060301

Title: Sprouty proteins are in vivo targets of Corkscrew/SHP-2 tyrosine phosphatases.

Journal: Development (Cambridge, England) 20060301

Title: Quantitative analysis of phosphotyrosine signaling networks triggered by CD3 and CD28 costimulation in Jurkat cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20060301

Title: Unique structural determinants for Stat3 recruitment and activation by the granulocyte colony-stimulating factor receptor at phosphotyrosine ligands 704 and 744.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20060301

Title: Tick vitellin is dephosphorylated by a protein tyrosine phosphatase during egg development: effect of dephosphorylation on VT proteolysis.

Journal: Insect biochemistry and molecular biology 20060301

Title: Correlation of in vitro cytokine responses with the chemical composition of soil-derived particulate matter.

Journal: Environmental health perspectives 20060301

Title: Signals for stress erythropoiesis are integrated via an erythropoietin receptor-phosphotyrosine-343-Stat5 axis.

Journal: The Journal of clinical investigation 20060301

Title: Quantitative phosphotyrosine proteomics of EphB2 signaling by stable isotope labeling with amino acids in cell culture (SILAC).

Journal: Journal of proteome research 20060301

Title: Dissection of a functional interaction between the DNA translocase, FtsK, and the XerD recombinase.

Journal: Molecular microbiology 20060301

Title: The dictyostelium kinome--analysis of the protein kinases from a simple model organism.

Journal: PLoS genetics 20060301

Title: Phosphoinositide, phosphopeptide and pyridone interactions of the Abl SH2 domain.

Journal: Chemical biology & drug design 20060301

Title: [Difference in methylation of genomic DNA between gastric primary cancer and lymph nodes with metastatic gastric cancer].

Journal: Zhonghua yi xue za zhi 20060227

Title: Binding of laminin alpha1-chain LG4-5 domain to alpha-dystroglycan causes tyrosine phosphorylation of syntrophin to initiate Rac1 signaling.

Journal: Biochemistry 20060221

Title: Scaffolding adapter Grb2-associated binder 2 requires Syk to transmit signals from FcepsilonRI.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20060215

Title: Functional hierarchy of the N-terminal tyrosines of SLP-76.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20060215

Title: Activation of the JAK-STAT signaling pathway in the rat basilar artery after subarachnoid hemorrhage.

Journal: Brain research 20060209

Title: HGF induction of postsynaptic specializations at the neuromuscular junction.

Journal: Journal of neurobiology 20060205

Title: Tryptase activates phosphatidylinositol 3-kinases proteolytically independently from proteinase-activated receptor-2 in cultured dog airway smooth muscle cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20060201

Title: Similarities and differences between the E5 oncoproteins of bovine papillomaviruses type 1 and type 4: cytoskeleton, motility and invasiveness in E5-transformed bovine and mouse cells.

Journal: Virus research 20060201

Title: Rapid single tube genotyping of ACP1 by FRET based amplification and dual color melting curve analysis.

Journal: Molecular and cellular probes 20060201

Title: AMBER force-field parameters for phosphorylated amino acids in different protonation states: phosphoserine, phosphothreonine, phosphotyrosine, and phosphohistidine.

Journal: Journal of molecular modeling 20060201

Title: Insulin receptor kinase-associated phosphotyrosine phosphatases in hepatic endosomes: assessing the role of phosphotyrosine phosphatase-1B.

Journal: Endocrinology 20060201

Title: Type II phosphatidylinositol 4-kinase beta associates with TCR-CD3 zeta chain in Jurkat cells.

Journal: Molecular immunology 20060201

Title: Endocytic pathways and biological effects induced by UVB-dependent or ligand-dependent activation of the keratinocyte growth factor receptor.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060201

Title: Differential steady-state tyrosine phosphorylation of two oligomeric forms of mitochondrial F0F1ATPsynthase: a structural proteomic analysis.

Journal: Proteomics 20060201

Title: Altered subcellular distribution of IRS-1 and IRS-3 is associated with defective Akt activation and GLUT4 translocation in insulin-resistant old rat adipocytes.

Journal: Biochimica et biophysica acta 20060201

Title: Differential phosphoprotein mapping in cancer cells using protein microarrays produced from 2-D liquid fractionation.

Journal: Analytical chemistry 20060201

Title: Effect of docosahexaenoic acid on interleukin-2 receptor signaling pathway in lipid rafts.

Journal: Science in China. Series C, Life sciences 20060201

Title: Inhibition of immune responses by ITAM-bearing receptors.

Journal: Science's STKE : signal transduction knowledge environment 20060131

Title: Minimal features of paxillin that are required for the tyrosine phosphorylation of focal adhesion kinase.

Journal: The Biochemical journal 20060115

Title: A quantitative protein interaction network for the ErbB receptors using protein microarrays.

Journal: Nature 20060112

Title: Pinpointing phosphotyrosine-dependent interactions downstream of the collagen receptor DDR1.

Journal: FEBS letters 20060109

Title: The dependence of fibrillar adhesions in human fibroblasts on substratum chemistry.

Journal: Biomaterials 20060101

Title: Hyperphosphorylation of JNK-interacting protein 1, a protein associated with Alzheimer disease.

Journal: Molecular & cellular proteomics : MCP 20060101

Title: Molecular basis for regulation of Src by the docking protein p130Cas.

Journal: Journal of molecular recognition : JMR 20060101

Title: Src activation of NF-kappaB augments IL-1beta-induced nitric oxide production in mesangial cells.

Journal: Journal of the American Society of Nephrology : JASN 20060101

Title: Use of detergents to increase selectivity of immunoprecipitation of tyrosine phosphorylated peptides prior to identification by MALDI quadrupole-TOF MS.

Journal: Proteomics 20060101

Title: RACK1 recruits STAT3 specifically to insulin and insulin-like growth factor 1 receptors for activation, which is important for regulating anchorage-independent growth.

Journal: Molecular and cellular biology 20060101

Title: A preliminary investigation into the action of anagrelide: thrombopoietin-c-Mpl receptor interactions.

Journal: Experimental hematology 20060101

Title: Genome-wide analysis and experimentation of plant serine/ threonine/tyrosine-specific protein kinases.

Journal: Plant molecular biology 20060101

Title: Protein kinases associated with the yeast phosphoproteome.

Journal: BMC bioinformatics 20060101

Title: The role of tyrosine phosphorylation in regulation of signal transduction pathways in unicellular eukaryotes.

Journal: Current issues in molecular biology 20060101

Title: The role of water in computational and experimental derivation of binding thermodynamics in SH2 domains.

Journal: Chemical biology & drug design 20060101

Title: Exploring supervised and unsupervised methods to detect topics in biomedical text.

Journal: BMC bioinformatics 20060101

Title: The p38 mitogen-activated protein kinase signaling cascade in CD4 T cells.

Journal: Arthritis research & therapy 20060101

Title: PPSP: prediction of PK-specific phosphorylation site with Bayesian decision theory.

Journal: BMC bioinformatics 20060101

Title: Changes in membrane lipid order with capacitation in rhesus macaque (Macaca mulatta) spermatozoa.

Journal: Journal of andrology 20060101

Title: Matrix metalloproteinase and tissue inhibitor of metalloproteinase in serum and synovial fluid of osteoarthritic dogs.

Journal: Veterinary and comparative orthopaedics and traumatology : V.C.O.T 20060101

Title: Abnormal glucose tolerance and insulin resistance in polycystic ovary syndrome amongst the Taiwanese population- not correlated with insulin receptor substrate-1 Gly972Arg/Ala513Pro polymorphism.

Journal: BMC medical genetics 20060101

Title: Different roles for non-receptor tyrosine kinases in arachidonate release induced by zymosan and Staphylococcus aureus in macrophages.

Journal: Journal of inflammation (London, England) 20060101

Title: Cancer and kinases: reports from the front line.

Journal: Genome biology 20060101

Title: The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium.

Journal: Breast cancer research : BCR 20060101

Title: NMR assignment of the phosphotyrosine binding (PTB) domain of tensin.

Journal: Journal of biomolecular NMR 20060101

Title: An active form of Vav1 induces migration of mammary epithelial cells by stimulating secretion of an epidermal growth factor receptor ligand.

Journal: Cell communication and signaling : CCS 20060101

Title: Nitric oxide agents impair insulin-mediated signal transduction in rat skeletal muscle.

Journal: BMC biochemistry 20060101

Title: The interactome of human EGF/ErbB receptors.

Journal: Molecular systems biology 20060101

Title: The proteomes of neurotransmitter receptor complexes form modular networks with distributed functionality underlying plasticity and behaviour.

Journal: Molecular systems biology 20060101

Title: Molecular profiling of signalling proteins for effects induced by the anti-cancer compound GSAO with 400 antibodies.

Journal: BMC cancer 20060101

Title: Insulin-like growth factor-1 (IGF-1) induces the activation/phosphorylation of Akt kinase and cAMP response element-binding protein (CREB) by activating different signaling pathways in PC12 cells.

Journal: BMC neuroscience 20060101

Title: Structure function analysis of SH2D2A isoforms expressed in T cells reveals a crucial role for the proline rich region encoded by SH2D2A exon 7.

Journal: BMC immunology 20060101

Title: Phosphoprotein analysis: from proteins to proteomes.

Journal: Proteome science 20060101

Title: Beta3 integrin and Src facilitate transforming growth factor-beta mediated induction of epithelial-mesenchymal transition in mammary epithelial cells.

Journal: Breast cancer research : BCR 20060101

Title: Redox-mediated bypass of restriction point via skipping of G1pm.

Journal: Theoretical biology & medical modelling 20060101

Title: Met-Independent Hepatocyte Growth Factor-mediated regulation of cell adhesion in human prostate cancer cells.

Journal: BMC cancer 20060101

Title: Detection of protein tyrosine phosphorylation by open sandwich fluoroimmunoassay.

Journal: Biotechnology progress 20060101

Title: Genome-wide gene expression profiling of human mast cells stimulated by IgE or FcepsilonRI-aggregation reveals a complex network of genes involved in inflammatory responses.

Journal: BMC genomics 20060101

Title: Design and synthesis of phosphonodifluoromethyl phenylalanine (F2Pmp): a useful phosphotyrosyl mimetic.

Journal: Current topics in medicinal chemistry 20060101

Title: Modulation of beta-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family.

Journal: Molecular neurodegeneration 20060101

Title: EGF-induced activation of Akt results in mTOR-dependent p70S6 kinase phosphorylation and inhibition of HC11 cell lactogenic differentiation.

Journal: BMC cell biology 20060101

Title: Effects of HER2 overexpression on cell signaling networks governing proliferation and migration.

Journal: Molecular systems biology 20060101

Title: Towards comprehensive characterization of HER2 overexpression.

Journal: Molecular systems biology 20060101

Title: Induction of acid phosphatase activity during germination of maize (Zea mays) seeds.

Journal: Plant physiology and biochemistry : PPB 20060101

Title: Tumor suppressor gene methylation in follicular lymphoma: a comprehensive review.

Journal: Molecular cancer 20060101

Title: Singlet oxygen inactivates protein tyrosine phosphatase-1B by oxidation of the active site cysteine.

Journal: Biological chemistry 20060101

Title: A statistical score for assessing the quality of multiple sequence alignments.

Journal: BMC bioinformatics 20060101

Title: Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription.

Journal: Retrovirology 20060101

Title: Induction of multiple matrix metalloproteinases in human dermal and synovial fibroblasts by Staphylococcus aureus: implications in the pathogenesis of septic arthritis and other soft tissue infections.

Journal: Arthritis research & therapy 20060101

Title: Abnormal insulin-like growth factor 1 signaling in human osteoarthritic subchondral bone osteoblasts.

Journal: Arthritis research & therapy 20060101

Title: Greenbottle (Lucilia sericata) larval secretions delivered from a prototype hydrogel wound dressing accelerate the closure of model wounds.

Journal: Biotechnology progress 20060101

Title: The expression and action of decay-accelerating factor (CD55) in human malignancies and cancer therapy.

Journal: Cellular oncology : the official journal of the International Society for Cellular Oncology 20060101

Title: Xenopus Dab2 is required for embryonic angiogenesis.

Journal: BMC developmental biology 20060101

Title: Cooperation between engulfment receptors: the case of ABCA1 and MEGF10.

Journal: PloS one 20060101

Title: Tyrosine-specific MAPK phosphatases and the control of ERK signaling in PC12 cells.

Journal: Journal of molecular signaling 20060101

Title: Amino terminal tyrosine phosphorylation of human MIXL1.

Journal: Journal of molecular signaling 20060101

Title: [Peculiarities of dephosphorylation reaction catalyzed by purified protein tyrosine phosphatase CD45 from thymocytes of intact and exposed to ionising radiation rats].

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20060101

Title: [Global gene expression analysis and novel signalling pathways in Hodgkin lymphoma].

Journal: Verhandlungen der Deutschen Gesellschaft fur Pathologie 20060101

Title: Role of 14-3-3gamma in FE65-dependent gene transactivation mediated by the amyloid beta-protein precursor cytoplasmic fragment.

Journal: The Journal of biological chemistry 20051223

Title: Signals of seminal vesicle autoantigen suppresses bovine serum albumin-induced capacitation in mouse sperm.

Journal: Biochemical and biophysical research communications 20051223

Title: SLAM-associated protein as a potential negative regulator in Trk signaling.

Journal: The Journal of biological chemistry 20051216

Title: The modular adaptor protein autosomal recessive hypercholesterolemia (ARH) promotes low density lipoprotein receptor clustering into clathrin-coated pits.

Journal: The Journal of biological chemistry 20051209

Title: Leptin potentiates ADP-induced [Ca(2+)](i) increase via JAK2 and tyrosine kinases in a megakaryoblast cell line.

Journal: Diabetes research and clinical practice 20051201

Title: Muscle contractions, AICAR, and insulin cause phosphorylation of an AMPK-related kinase.

Journal: American journal of physiology. Endocrinology and metabolism 20051201

Title: Genistein-induced neuronal differentiation is associated with activation of extracellular signal-regulated kinases and upregulation of p21 and N-cadherin.

Journal: Journal of cellular biochemistry 20051201

Title: Highly sensitive peptide-based probes for protein tyrosine phosphatase activity utilizing a fluorogenic mimic of phosphotyrosine.

Journal: Bioorganic & medicinal chemistry letters 20051201

Title: The integrin alpha6beta1 modulation of PI3K and Cdc42 activities induces dynamic filopodium formation in human platelets.

Journal: Journal of biomedical science 20051201

Title: Intrabacterial proton-dependent CagA transport system in Helicobacter pylori.

Journal: Journal of medical microbiology 20051201

Title: Systematic discovery of new recognition peptides mediating protein interaction networks.

Journal: PLoS biology 20051201

Title: Secondary structure assignment of mouse SOCS3 by NMR defines the domain boundaries and identifies an unstructured insertion in the SH2 domain.

Journal: The FEBS journal 20051201

Title: Cellular prostatic acid phosphatase: a protein tyrosine phosphatase involved in androgen-independent proliferation of prostate cancer.

Journal: Endocrine-related cancer 20051201

Title: Helicobacter pylori CagA: a new paradigm for bacterial carcinogenesis.

Journal: Cancer science 20051201

Title: Probing the secondary structure of a recombinant neuronal adaptor protein and its phosphotyrosine binding domains.

Journal: Bioscience, biotechnology, and biochemistry 20051201

Title: Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor.

Journal: Biochemical and biophysical research communications 20051111

Title: Epidermal growth factor induces tyrosine phosphorylation, membrane insertion, and activation of transient receptor potential channel 4.

Journal: The Journal of biological chemistry 20051111

Title: MHC class II/CD38/CD9: a lipid-raft-dependent signaling complex in human monocytes.

Journal: Blood 20051101

Title: CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy.

Journal: Blood 20051101

Title: Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling.

Journal: Blood 20051101

Title: EGF receptor activity is essential for adhesion-induced stress fiber formation and cofilin phosphorylation.

Journal: Cellular signalling 20051101

Title: Phosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform.

Journal: Molecular and cellular biology 20051101

Title: Modeling T cell antigen discrimination based on feedback control of digital ERK responses.

Journal: PLoS biology 20051101

Title: The synaptic muscle-specific kinase (MuSK) complex: new partners, new functions.

Journal: BioEssays : news and reviews in molecular, cellular and developmental biology 20051101

Title: Helicobacter pylori-stimulated interleukin-8 (IL-8) promotes cell proliferation through transactivation of epidermal growth factor receptor (EGFR) by disintegrin and metalloproteinase (ADAM) activation.

Journal: Digestive diseases and sciences 20051101

Title: Expression patterns of purple acid phosphatase genes in Arabidopsis organs and functional analysis of AtPAP23 predominantly transcribed in flower.

Journal: Plant molecular biology 20051101

Title: Regulation of the wild-type and Y1235D mutant Met kinase activation.

Journal: Biochemistry 20051101

Title: Effects of dexmedetomidine on hippocampal focal adhesion kinase tyrosine phosphorylation in physiologic and ischemic conditions.

Journal: Anesthesiology 20051101

Title: Crystal structure of a complex between protein tyrosine phosphatase 1B and the insulin receptor tyrosine kinase.

Journal: Structure (London, England : 1993) 20051101

Title: Integrin alpha1beta1 mediates collagen induction of MMP-13 expression in MC615 chondrocytes.

Journal: Biochimica et biophysica acta 20051030

Title: Human Tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages.

Journal: The Journal of biological chemistry 20051028

Title: Concise approach to novel isothiazolidinone phosphotyrosine mimetics: microwave-assisted addition of bisulfite to activated olefins.

Journal: Organic letters 20051027

Title: Structure-based design and discovery of protein tyrosine phosphatase inhibitors incorporating novel isothiazolidinone heterocyclic phosphotyrosine mimetics.

Journal: Journal of medicinal chemistry 20051020

Title: Differential response to gefitinib of cells expressing normal EGFR and the mutant EGFRvIII.

Journal: British journal of cancer 20051017

Title: Evidence for the involvement of PECAM-1 in a receptor mediated signal-transduction pathway regulating capacitation-associated tyrosine phosphorylation in human spermatozoa.

Journal: Journal of cell science 20051015

Title: Insulin receptor substrate is a mediator of phosphoinositide 3-kinase activation in quiescent pancreatic cancer cells.

Journal: Cancer research 20051015

Title: Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain.

Journal: Journal of molecular biology 20051014

Title: CD40 ligand-dependent tyrosine nitration of prostacyclin synthase in vivo.

Journal: Circulation 20051004

Title: Disruption of Sertoli-germ cell adhesion function in the seminiferous epithelium of the rat testis can be limited to adherens junctions without affecting the blood-testis barrier integrity: an in vivo study using an androgen suppression model.

Journal: Journal of cellular physiology 20051001

Title: Simultaneous activation of JAK1 and JAK2 confers IL-3 independent growth on Ba/F3 pro-B cells.

Journal: Journal of cellular biochemistry 20051001

Title: Grb2 negatively regulates epidermal growth factor-induced phospholipase C-gamma1 activity through the direct interaction with tyrosine-phosphorylated phospholipase C-gamma1.

Journal: Cellular signalling 20051001

Title: Tyrosine phosphatases as regulators of skeletal development and metabolism.

Journal: Journal of cellular biochemistry 20051001

Title: Vitamin D receptor agonists induce prostatic acid phosphatase to reduce cell growth and HER-2 signaling in LNCaP-derived human prostate cancer cells.

Journal: The Journal of steroid biochemistry and molecular biology 20051001

Title: Insulin, glucagon and fatty acid treatment of hepatocytes does not result in phosphorylation or changes in activity of triacylglycerol hydrolase.

Journal: Biochimica et biophysica acta 20051001

Title: Phosphotyrosine binding-mediated oligomerization of downstream of tyrosine kinase (Dok)-1 and Dok-2 is involved in CD2-induced Dok phosphorylation.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20051001

Title: Hypoxia-induced post-translational changes in red blood cell protein map of newborns.

Journal: Pediatric research 20051001

Title: Combined Abl inhibitor therapy for minimizing drug resistance in chronic myeloid leukemia: Src/Abl inhibitors are compatible with imatinib.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20051001

Title: Increased tyrosine phosphorylation of platelet proteins including pp125(FAK) suggests endogenous activation and aggregation in pulmonary hypertension.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20051001

Title: [Negative regulation of the JAK/STAT: pathway implication in tumorigenesis].

Journal: Bulletin du cancer 20051001

Title: Actin cytoskeleton remodelling in the anterior pituitary folliculostellate cell line TtT/GF: participation of the actin-binding protein cortactin.

Journal: Journal of molecular histology 20051001

Title: Neuro-apoptogenic and blood platelet targeting toxins in benthic marine cyanobacteria from the Portuguese coast.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20050930

Title: Phase II trial of tamoxifen and goserelin in recurrent epithelial ovarian cancer.

Journal: British journal of cancer 20050919

Title: Pleiotrophin stimulates tyrosine phosphorylation of beta-adducin through inactivation of the transmembrane receptor protein tyrosine phosphatase beta/zeta.

Journal: Biochemical and biophysical research communications 20050916

Title: Alternative mode of binding to phosphotyrosyl peptides by Src homology-2 domains.

Journal: Biochemistry 20050913

Title: Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation. Contributions of Src- and receptor-tyrosine kinases.

Journal: The Journal of biological chemistry 20050909

Title: Lessons from nature: On the molecular recognition elements of the phosphoprotein binding-domains.

Journal: Biotechnology and bioengineering 20050905

Title: SarCNU-induced G2/M arrest in hepatoma cells is mediated by a p53-independent phosphorylation of cdc-2 at Tyr15.

Journal: Journal of cellular physiology 20050901

Title: Docosahexaenoic acid induces apoptosis in proliferating human endothelial cells.

Journal: Journal of cellular physiology 20050901

Title: Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.

Journal: Molecular & cellular proteomics : MCP 20050901

Title: CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis.

Journal: Human molecular genetics 20050901

Title: Sam68 is tyrosine phosphorylated and recruited to signalling in peripheral blood mononuclear cells from HIV infected patients.

Journal: Clinical and experimental immunology 20050901

Title: Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin.

Journal: Development (Cambridge, England) 20050901

Title: FAS associated phosphatase (FAP-1) blocks apoptosis of astrocytomas through dephosphorylation of FAS.

Journal: Journal of neuro-oncology 20050901

Title: Association/dissociation of a channel-kinase complex underlies state-dependent modulation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050831

Title: Tumor cell pseudopodial protrusions. Localized signaling domains coordinating cytoskeleton remodeling, cell adhesion, glycolysis, RNA translocation, and protein translation.

Journal: The Journal of biological chemistry 20050826

Title: Activation of the neuregulin-1/ErbB signaling pathway promotes the proliferation of neoplastic Schwann cells in human malignant peripheral nerve sheath tumors.

Journal: Oncogene 20050825

Title: Cooperation between artificial receptors and supramolecular hydrogels for sensing and discriminating phosphate derivatives.

Journal: Journal of the American Chemical Society 20050824

Title: Flow activates ERK1/2 and endothelial nitric oxide synthase via a pathway involving PECAM1, SHP2, and Tie2.

Journal: The Journal of biological chemistry 20050819

Title: Src-dependent tyrosine phosphorylation at the tips of growth cone filopodia promotes extension.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050817

Title: Effector-induced Syk-mediated phosphorylation in human erythrocytes.

Journal: Biochimica et biophysica acta 20050815

Title: Design and synthesis of 4-(alpha-hydroxymalonyl)phenylalanine as a new phosphotyrosyl mimetic and its use in growth factor receptor bound 2 src-homology 2 (Grb2 SH2) domain-binding peptides.

Journal: Journal of medicinal chemistry 20050811

Title: EGF-induced EGF-receptor and MAP kinase phosphorylation in goat cumulus cells during in vitro maturation.

Journal: Molecular reproduction and development 20050801

Title: Systematic analysis of the epidermal growth factor receptor by mass spectrometry reveals stimulation-dependent multisite phosphorylation.

Journal: Molecular & cellular proteomics : MCP 20050801

Title: 17 beta-estradiol transiently disrupts adherens junctions in endothelial cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050801

Title: Loss of Zap-70 and low molecular weight phosphotyrosine phosphatase occurs after therapy in a patient with B-chronic lymphocytic leukemia.

Journal: Leukemia 20050801

Title: FcepsilonRI cross-linking activates a type II phosphatidylinositol 4-kinase in RBL 2H3 cells.

Journal: Molecular immunology 20050801

Title: Activation of the lysosome-associated p61Hck isoform triggers the biogenesis of podosomes.

Journal: Traffic (Copenhagen, Denmark) 20050801

Title: Phospho-specific antibodies: more valuable than originally thought.

Journal: American journal of physiology. Renal physiology 20050801

Title: Integrin activation by talin.

Journal: Journal of thrombosis and haemostasis : JTH 20050801

Title: Okadaic acid induces tyrosine phosphorylation of IkappaBalpha that mediated by PKR pathway in human osteoblastic MG63 cells.

Journal: Molecular and cellular biochemistry 20050801

Title: Imaging epidermal growth factor receptor phosphorylation in human colorectal cancer cells and human tissues.

Journal: The Journal of biological chemistry 20050729

Title: Mitochondrial Dok-4 recruits Src kinase and regulates NF-kappaB activation in endothelial cells.

Journal: The Journal of biological chemistry 20050715

Title: Subconfluent endothelial cells form podosomes downstream of cytokine and RhoGTPase signaling.

Journal: Experimental cell research 20050715

Title: PTPN11 mutations play a minor role in isolated congenital heart disease.

Journal: American journal of medical genetics. Part A 20050715

Title: Tyrosine phosphorylation of paxillin affects the metastatic potential of human osteosarcoma.

Journal: Oncogene 20050714

Title: Phosphorylation of an alpha-synuclein peptide fragment enhances metal binding.

Journal: Journal of the American Chemical Society 20050713

Title: Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050713

Title: Orientations of nematic liquid crystals on surfaces presenting controlled densities of peptides: amplification of protein-peptide binding events.

Journal: Langmuir : the ACS journal of surfaces and colloids 20050705

Title: Transmembrane homodimerization of receptor-like protein tyrosine phosphatases.

Journal: FEBS letters 20050704

Title: Synthesis of linear and cyclic phosphopeptides as ligands for the N-terminal SH2-domain of protein tyrosine phosphatase SHP-1.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20050701

Title: The role of protein-tyrosine phosphatase 1B in integrin signaling.

Journal: The Journal of biological chemistry 20050701

Title: Synthesis of a C-terminally biotinylated macrocyclic peptide mimetic exhibiting high Grb2 SH2 domain-binding affinity.

Journal: Bioorganic & medicinal chemistry 20050701

Title: Binding of a diphosphorylated-ITAM peptide to spleen tyrosine kinase (Syk) induces distal conformational changes: a hydrogen exchange mass spectrometry study.

Journal: Journal of the American Society for Mass Spectrometry 20050701

Title: Atypical regulation of a green lineage-specific B-type cyclin-dependent kinase.

Journal: Plant physiology 20050701

Title: Redox-regulated affinity of the third PDZ domain in the phosphotyrosine phosphatase PTP-BL for cysteine-containing target peptides.

Journal: The FEBS journal 20050701

Title: Detection and quantification of on-chip phosphorylated peptides by surface plasmon resonance imaging techniques using a phosphate capture molecule.

Journal: Analytical chemistry 20050701

Title: [Identification of proteins interacting with adaptor protein Bam32].

Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20050701

Title: Induction of apoptosis in the lung tissue from rats exposed to cigarette smoke involves p38/JNK MAPK pathway.

Journal: Chemico-biological interactions 20050630

Title: Phosphatidylinositol phosphate kinase type Igamma directly associates with and regulates Shp-1 tyrosine phosphatase.

Journal: The Journal of biological chemistry 20050624

Title: CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells.

Journal: Oncogene 20050623

Title: Inhibitors of protein tyrosine phosphatases: next-generation drugs?

Journal: Angewandte Chemie (International ed. in English) 20050620

Title: Analysis of total phosphotyrosine levels in CD34+ cells from CML patients to predict the response to imatinib mesylate treatment.

Journal: Blood 20050615

Title: In situ photoactivation of a caged phosphotyrosine peptide derived from focal adhesion kinase temporarily halts lamellar extension of single migrating tumor cells.

Journal: The Journal of biological chemistry 20050610

Title: Identification of a NPXY motif in growth factor receptor-bound protein 14 (Grb14) and its interaction with the phosphotyrosine-binding (PTB) domain of IRS-1.

Journal: Biochemistry 20050607

Title: Identification of B cell adaptor for PI3-kinase (BCAP) as an Abl interactor 1-regulated substrate of Abl kinases.

Journal: FEBS letters 20050606

Title: Phosphorylation of a tyrosine at the N-terminus regulates the surface expression of GIRK5 homomultimers.

Journal: FEBS letters 20050606

Title: Knock-down of LAR protein tyrosine phosphatase induces insulin resistance.

Journal: FEBS letters 20050606

Title: SOCS-1 inhibits expression of the antiviral proteins 2',5'-OAS and MxA induced by the novel interferon-lambdas IL-28A and IL-29.

Journal: Biochemical and biophysical research communications 20050603

Title: Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography.

Journal: Molecular & cellular proteomics : MCP 20050601

Title: Hydrogen peroxide and epidermal growth factor activate phosphatidylinositol 3-kinase and increase sodium transport in A6 cell monolayers.

Journal: American journal of physiology. Renal physiology 20050601

Title: Genomic organization of the channel catfish CD45 functional gene and CD45 pseudogenes.

Journal: Immunogenetics 20050601

Title: Two-stage affinity purification for inducibly phosphorylated membrane proteins.

Journal: Proteomics 20050601

Title: A beta4 integrin-like protein co-localises with a phosphotyrosine containing protein in the oomycete Achlya bisexualis: inhibition of tyrosine phosphorylation slows tip growth.

Journal: Fungal genetics and biology : FG & B 20050601

Title: Phosphorylation-driven protein-protein interactions: a protein kinase sensing system.

Journal: Journal of the American Chemical Society 20050601

Title: Studies of tyrosine phosphorylation and Src family tyrosine kinases in the lens epithelium.

Journal: Investigative ophthalmology & visual science 20050601

Title: Association testing of the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes in 7,883 people.

Journal: Diabetes 20050601

Title: Capacitation-associated protein tyrosine phosphorylation and membrane fluidity changes are impaired in the spermatozoa of asthenozoospermic patients.

Journal: Reproduction (Cambridge, England) 20050601

Title: Altered protein tyrosine phosphorylation in asthmatic bronchial epithelium.

Journal: The European respiratory journal 20050601

Title: Protein phosphorylation in signaling--50 years and counting.

Journal: Trends in biochemical sciences 20050601

Title: The effect of simvastatin on the proliferation and differentiation of human bone marrow stromal cells.

Journal: Journal of Korean medical science 20050601

Title: Frequent KIT and epidermal growth factor receptor overexpressions in undifferentiated-type breast carcinomas with 'stem-cell-like' features.

Journal: Cancer science 20050601

Title: [Differential analysis of tyrosine-phosphorylated proteins in human hepatocellular carcinoma cell lines with different metastasis potentials].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20050601

Title: Inhibitory activity on matrix metalloproteinases and cell-proliferating activity of tissue inhibitor of metalloproteinases-1 (TIMP-1)-contrastive difference between human and bovine TIMP-1s on mouse cell proliferation.

Journal: Growth factors (Chur, Switzerland) 20050601

Title: Src-mediated tyrosine phosphorylation of p47phox in hyperoxia-induced activation of NADPH oxidase and generation of reactive oxygen species in lung endothelial cells.

Journal: The Journal of biological chemistry 20050527

Title: Src kinase regulation by phosphorylation and dephosphorylation.

Journal: Biochemical and biophysical research communications 20050527

Title: Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II.

Journal: Nature 20050519

Title: PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia.

Journal: Blood 20050515

Title: Autocrine- and paracrine-activated receptor tyrosine kinases in classic Hodgkin lymphoma.

Journal: Blood 20050515

Title: Transmembrane CEACAM1 affects integrin-dependent signaling and regulates extracellular matrix protein-specific morphology and migration of endothelial cells.

Journal: Blood 20050515

Title: Rapid ubiquitination of Syk following GPVI activation in platelets.

Journal: Blood 20050515

Title: c-Abl tyrosine kinase regulates c-fos gene expression via phosphorylating RNA polymerase II.

Journal: Archives of biochemistry and biophysics 20050515

Title: Anti-IgM induces up-regulation and tyrosine-phosphorylation of heterogeneous nuclear ribonucleoprotein K proteins (hnRNP K) in a Ramos B cell line.

Journal: Immunology letters 20050515

Title: Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteins.

Journal: The Journal of biological chemistry 20050513

Title: Extracellular signal-dependent nuclear import of STAT3 is mediated by various importin alphas.

Journal: Biochemical and biophysical research communications 20050513

Title: The SH2-domian-containing inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via tyrosine residue 1356 and involves hepatocyte growth factor (HGF)-induced lamellipodium formation, cell scattering and cell spreading.

Journal: Oncogene 20050512

Title: Cucurbitacin Q: a selective STAT3 activation inhibitor with potent antitumor activity.

Journal: Oncogene 20050505

Title: Impact of SRC homology 2-containing inositol 5'-phosphatase 2 gene polymorphisms detected in a Japanese population on insulin signaling.

Journal: The Journal of clinical endocrinology and metabolism 20050501

Title: Changes in tyrosine phosphorylation associated with true capacitation and capacitation-like state in boar spermatozoa.

Journal: Molecular reproduction and development 20050501

Title: A new approach for sequencing human IRS1 phosphotyrosine-containing peptides using CapLC-Q-TOF(micro).

Journal: Journal of mass spectrometry : JMS 20050501

Title: Expression, purification, and characterization of rat protein tyrosine phosphatase eta catalytic domain.

Journal: Protein expression and purification 20050501

Title: Magnesium sulfate effect on erythrocyte membranes of asphyxiated newborns.

Journal: Clinical biochemistry 20050501

Title: EphrinB-EphB signalling regulates clathrin-mediated endocytosis through tyrosine phosphorylation of synaptojanin 1.

Journal: Nature cell biology 20050501

Title: Insulin-like growth factor-1 controls type 2 T cell-independent B cell response.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20050501

Title: Apolipoprotein J (clusterin) activates rodent microglia in vivo and in vitro.

Journal: Journal of neurochemistry 20050501

Title: Ephrin tempers two-faced synaptojanin 1.

Journal: Nature cell biology 20050501

Title: Localisation of high acid phosphotyrosine phosphatase activity in afferent arterioles and glomeruli of human kidney.

Journal: Journal of molecular histology 20050501

Title: Domain-specific function of ShcC docking protein in neuroblastoma cells.

Journal: Oncogene 20050428

Title: The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue.

Journal: Oncogene 20050428

Title: CTLA-4 is important in maintaining long-term survival of cardiac allografts.

Journal: Transplantation 20050427

Title: Somatostatin receptors 2 and 5 are preferentially expressed in proliferating endothelium.

Journal: British journal of cancer 20050425

Title: Fyn binding protein, Fyb, interacts with mammalian actin binding protein, mAbp1.

Journal: FEBS letters 20050425

Title: C2 can do it, too.

Journal: Cell 20050422

Title: The C2 domain of PKCdelta is a phosphotyrosine binding domain.

Journal: Cell 20050422

Title: Size-selected (2-10 nm) gold nanoparticles for matrix assisted laser desorption ionization of peptides.

Journal: Journal of the American Chemical Society 20050420

Title: Rapid enrichment and analysis of yeast phosphoproteins using affinity chromatography, 2D-PAGE and peptide mass fingerprinting.

Journal: Yeast (Chichester, England) 20050415

Title: Unexpected relative aqueous solubilities of a phosphotyrosine analogue and two phosphonate derivatives.

Journal: Journal of the American Chemical Society 20050406

Title: Somatostatin-induced activation and up-regulation of N-methyl-D-aspartate receptor function: mediation through calmodulin-dependent protein kinase II, phospholipase C, protein kinase C, and tyrosine kinase in hippocampal noradrenergic nerve endings.

Journal: The Journal of pharmacology and experimental therapeutics 20050401

Title: The sulfogalactose moiety of sulfoglycosphingolipids serves as a mimic of tyrosine phosphate in many recognition processes. Prediction and demonstration of Src homology 2 domain/sulfogalactose binding.

Journal: The Journal of biological chemistry 20050401

Title: Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells.

Journal: Molecular & cellular proteomics : MCP 20050401

Title: Ring-closing metathesis of C-terminal allylglycine residues with an N-terminal beta-vinyl-substituted phosphotyrosyl mimetic as an approach to novel Grb2 SH2 domain-binding macrocycles.

Journal: Chembiochem : a European journal of chemical biology 20050401

Title: Characterization of endocytic vesicles using magnetic microbeads coated with signalling ligands.

Journal: Traffic (Copenhagen, Denmark) 20050401

Title: Evaluation of macrocyclic Grb2 SH2 domain-binding peptide mimetics prepared by ring-closing metathesis of C-terminal allylglycines with an N-terminal beta-vinyl-substituted phosphotyrosyl mimetic.

Journal: Bioorganic & medicinal chemistry 20050401

Title: Using proteomics to identify potential therapeutic targets in platelets.

Journal: Biochemical Society transactions 20050401

Title: Nck-independent actin assembly is mediated by two phosphorylated tyrosines within enteropathogenic Escherichia coli Tir.

Journal: Molecular microbiology 20050401

Title: PrpZ, a Salmonella enterica serovar Typhi serine/threonine protein phosphatase 2C with dual substrate specificity.

Journal: Microbiology (Reading, England) 20050401

Title: Protein tyrosine phosphatases and signalling.

Journal: The Journal of endocrinology 20050401

Title: Syndecan-4 is a signaling molecule for stromal cell-derived factor-1 (SDF-1)/ CXCL12.

Journal: The FEBS journal 20050401

Title: The amyloid precursor protein and its network of interacting proteins: physiological and pathological implications.

Journal: Brain research. Brain research reviews 20050401

Title: Somatostatin: a hormone for the heart?

Journal: Current vascular pharmacology 20050401

Title: Matrix metalloproteinase 19 processes the laminin 5 gamma 2 chain and induces epithelial cell migration.

Journal: Cellular and molecular life sciences : CMLS 20050401

Title: Solution structure of the Src homology 2 domain from the human feline sarcoma oncogene Fes.

Journal: Journal of biomolecular NMR 20050401

Title: Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis.

Journal: Oncogene 20050317

Title: Cbl-mediated ubiquitination of alpha5 integrin subunit mediates fibronectin-dependent osteoblast detachment and apoptosis induced by FGFR2 activation.

Journal: Journal of cell science 20050315

Title: The p95-100 kDa ligand of the T cell-specific adaptor (TSAd) protein Src-homology-2 (SH2) domain implicated in TSAd nuclear import is p97 Valosin-containing protein (VCP).

Journal: Immunology letters 20050315

Title: Phosphorylation of carboxyl-terminal tyrosines modulates the specificity of Sprouty-2 inhibition of different signaling pathways.

Journal: The Journal of biological chemistry 20050311

Title: Design and biological evaluation of linear and cyclic phosphopeptide ligands of the N-terminal SH2 domain of protein tyrosine phosphatase SHP-1.

Journal: Journal of medicinal chemistry 20050310

Title: Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket.

Journal: The Journal of biological chemistry 20050304

Title: Regulation of connexin43-protein binding in astrocytes in response to chemical ischemia/hypoxia.

Journal: The Journal of biological chemistry 20050304

Title: Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions.

Journal: The Journal of biological chemistry 20050304

Title: Intracellular protein phosphorylation in adherent U937 monocytes mediated by various culture conditions and fibronectin-derived surface ligands.

Journal: Biomaterials 20050301

Title: T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells.

Journal: Journal of cellular biochemistry 20050301

Title: beta-Phenylethyl isothiocyanate mediated apoptosis: a proteomic investigation of early apoptotic protein changes.

Journal: Proteomics 20050301

Title: Zedoariae rhizoma and curcumin inhibits platelet-derived growth factor-induced proliferation of human hepatic myofibroblasts.

Journal: International immunopharmacology 20050301

Title: Mutation of chicken anemia virus VP2 differentially affects serine/threonine and tyrosine protein phosphatase activities.

Journal: The Journal of general virology 20050301

Title: A nonspecific phosphotyrosine phosphatase inhibitor, bis(maltolato)oxovanadium(IV), improves glucose tolerance and prevents diabetes in Zucker diabetic fatty rats.

Journal: Experimental biology and medicine (Maywood, N.J.) 20050301

Title: Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain.

Journal: PLoS medicine 20050301

Title: G-protein signaling: back to the future.

Journal: Cellular and molecular life sciences : CMLS 20050301

Title: Transient activation of Ras-dependent signalling at the early stages of Herbimycin A induced erythroid differentiation of human K562 cells.

Journal: Experimental oncology 20050301

Title: Comparative status of activated ERK1/2 and PARP cleavage in human gliomas.

Journal: Neuropathology : official journal of the Japanese Society of Neuropathology 20050301

Title: Site-specific pseudophosphorylation modulates the rate of tau filament dissociation.

Journal: FEBS letters 20050227

Title: A newly synthetic chromium complex--chromium(phenylalanine)3 improves insulin responsiveness and reduces whole body glucose tolerance.

Journal: FEBS letters 20050227

Title: Angiotensin II induces focal adhesion kinase/paxillin phosphorylation and cell migration in human umbilical vein endothelial cells.

Journal: Biochemical and biophysical research communications 20050225

Title: Amlodipine ameliorates myocardial hypertrophy by inhibiting EGFR phosphorylation.

Journal: Biochemical and biophysical research communications 20050225

Title: cAMP-dependent tyrosine phosphorylation of subunit I inhibits cytochrome c oxidase activity.

Journal: The Journal of biological chemistry 20050218

Title: FLT3/ITD mutation signaling includes suppression of SHP-1.

Journal: The Journal of biological chemistry 20050218

Title: Srcasm modulates EGF and Src-kinase signaling in keratinocytes.

Journal: The Journal of biological chemistry 20050218

Title: Identification of a molecular recognition role for the activation loop phosphotyrosine of the SRC tyrosine kinase.

Journal: Journal of the American Chemical Society 20050216

Title: Hippocampal synaptic modulation by the phosphotyrosine adapter protein ShcC/N-Shc via interaction with the NMDA receptor.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050216

Title: Regulation of Src kinase activity during Xenopus oocyte maturation.

Journal: Developmental biology 20050215

Title: Defective proximal TCR signaling inhibits CD8+ tumor-infiltrating lymphocyte lytic function.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20050215

Title: Cross-linking of 4-1BB activates TCR-signaling pathways in CD8+ T lymphocytes.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20050215

Title: The SH2 domain: versatile signaling module and pharmaceutical target.

Journal: Biochimica et biophysica acta 20050214

Title: Tyrosine kinase inhibitors attenuate Japanese encephalitis virus-induced neurotoxicity.

Journal: Biochemical and biophysical research communications 20050211

Title: Tyrosine 769 of the keratinocyte growth factor receptor is required for receptor signaling but not endocytosis.

Journal: Biochemical and biophysical research communications 20050211

Title: Comparative analysis of the signaling capabilities of the insulin receptor-related receptor.

Journal: Biochemical and biophysical research communications 20050211

Title: Surface plasmon resonance thermodynamic and kinetic analysis as a strategic tool in drug design. Distinct ways for phosphopeptides to plug into Src- and Grb2 SH2 domains.

Journal: Journal of medicinal chemistry 20050210

Title: Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics.

Journal: Journal of medicinal chemistry 20050210

Title: Probing the communication between the regulatory and catalytic domains of a protein tyrosine kinase, Csk.

Journal: Biochemistry 20050208

Title: Peptidomics, current status.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050205

Title: Photophysics and biological applications of the environment-sensitive fluorophore 6-N,N-dimethylamino-2,3-naphthalimide.

Journal: Journal of the American Chemical Society 20050202

Title: Involvement of adenylate cyclase and tyrosine kinase signaling pathways in response of crayfish stretch receptor neuron and satellite glia cell to photodynamic treatment.

Journal: Glia 20050201

Title: Theoretical investigations of prostatic acid phosphatase.

Journal: Proteins 20050201

Title: Right time, right place: the organization of membrane proximal signaling.

Journal: Seminars in immunology 20050201

Title: Connective tissue growth factor CCN2 interacts with and activates the tyrosine kinase receptor TrkA.

Journal: Journal of the American Society of Nephrology : JASN 20050201

Title: Application of metal-chelate affinity chromatography to the study of the phosphoproteome.

Journal: Amino acids 20050201

Title: The respiratory syncytial virus small hydrophobic protein is phosphorylated via a mitogen-activated protein kinase p38-dependent tyrosine kinase activity during virus infection.

Journal: The Journal of general virology 20050201

Title: Molecular and cellular pathogenesis of X-linked lymphoproliferative disease.

Journal: Immunological reviews 20050201

Title: Vascular endothelial-cadherin tyrosine phosphorylation in angiogenic and quiescent adult tissues.

Journal: Circulation research 20050201

Title: Onychin inhibits proliferation of vascular smooth muscle cells by regulating cell cycle.

Journal: Acta pharmacologica Sinica 20050201

Title: Induction of human sperm capacitation and protein tyrosine phosphorylation by endometrial cells and interleukin-6.

Journal: Molecular human reproduction 20050201

Title: Phosphodiesterase 4 inhibition decreases MUC5AC expression induced by epidermal growth factor in human airway epithelial cells.

Journal: Thorax 20050201

Title: Focal adhesion kinase regulates metastatic adhesion of carcinoma cells within liver sinusoids.

Journal: The American journal of pathology 20050201

Title: TINS, target immobilized NMR screening: an efficient and sensitive method for ligand discovery.

Journal: Chemistry & biology 20050201

Title: Distinct Grb10 domain requirements for effects on glucose uptake and insulin signaling.

Journal: Molecular and cellular endocrinology 20050131

Title: Regulation of upstream binding factor 1 activity by insulin-like growth factor I receptor signaling.

Journal: The Journal of biological chemistry 20050128

Title: Prion-associated increases in Src-family kinases.

Journal: The Journal of biological chemistry 20050128

Title: T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.

Journal: Science (New York, N.Y.) 20050121

Title: NMR dynamics-derived insights into the binding properties of a peptide interacting with an SH2 domain.

Journal: Biochemistry 20050118

Title: Characterization of a plant, tyrosine-specific phosphatase of the aspartyl class.

Journal: Biochemistry 20050118

Title: Use of phosphoproteomics to study tyrosine kinase activity in capacitating boar sperm. Kinase activity and capacitation.

Journal: Theriogenology 20050115

Title: Diazinon alters sperm chromatin structure in mice by phosphorylating nuclear protamines.

Journal: Toxicology and applied pharmacology 20050115

Title: The Notch regulator Numb links the Notch and TCR signaling pathways.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20050115

Title: The conserved immunoglobulin domain controls the subcellular localization of the homophilic adhesion receptor protein-tyrosine phosphatase mu.

Journal: The Journal of biological chemistry 20050114

Title: Novel mechanism of interaction of p85 subunit of phosphatidylinositol 3-kinase and ErbB3 receptor-derived phosphotyrosyl peptides.

Journal: The Journal of biological chemistry 20050114

Title: Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinase.

Journal: The Journal of biological chemistry 20050114

Title: RGS12 interacts with the SNARE-binding region of the Cav2.2 calcium channel.

Journal: The Journal of biological chemistry 20050114

Title: Neurotrophin-dependent tyrosine phosphorylation of Ras guanine-releasing factor 1 and associated neurite outgrowth is dependent on the HIKE domain of TrkA.

Journal: The Journal of biological chemistry 20050107

Title: Structural and evolutionary division of phosphotyrosine binding (PTB) domains.

Journal: Journal of molecular biology 20050107

Title: Proteomic analysis of phosphotyrosyl proteins in morphine-dependent rat brains.

Journal: Brain research. Molecular brain research 20050105

Title: Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors.

Journal: The Journal of clinical investigation 20050103

Title: Nongenomic effects of 17beta-estradiol in human platelets: potentiation of thrombin-induced aggregation through estrogen receptor beta and Src kinase.

Journal: Blood 20050101

Title: TNFalpha-induced insulin resistance in adipocytes as a membrane microdomain disorder: involvement of ganglioside GM3.

Journal: Glycobiology 20050101

Title: Tumor suppressor function of Bruton tyrosine kinase is independent of its catalytic activity.

Journal: Blood 20050101

Title: Identification of a novel activating mutation (Y842C) within the activation loop of FLT3 in patients with acute myeloid leukemia (AML).

Journal: Blood 20050101

Title: Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412.

Journal: Blood 20050101

Title: Bombesin and angiotensin II rapidly stimulate Src phosphorylation at Tyr-418 in fibroblasts and intestinal epithelial cells through a PP2-insensitive pathway.

Journal: Cellular signalling 20050101

Title: The protein kinase C inhibitor Go6976 [12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole] potentiates agonist-induced mitogen-activated protein kinase activation through tyrosine phosphorylation of the epidermal growth factor receptor.

Journal: Molecular pharmacology 20050101

Title: Listeria monocytogenes produces a pro-invasive factor that signals via ErbB2/ErbB3 heterodimers.

Journal: Journal of cancer research and clinical oncology 20050101

Title: Automated immobilized metal affinity chromatography/nano-liquid chromatography/electrospray ionization mass spectrometry platform for profiling protein phosphorylation sites.

Journal: Rapid communications in mass spectrometry : RCM 20050101

Title: Measurement of protein tyrosine phosphorylation in cell adhesion.

Journal: Methods in molecular biology (Clifton, N.J.) 20050101

Title: Risk of type 1 diabetes in childhood and maternal age at delivery, interaction with ACP1 and sex.

Journal: Diabetes/metabolism research and reviews 20050101

Title: Regulation of receptor protein-tyrosine phosphatase dimerization.

Journal: Methods (San Diego, Calif.) 20050101

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

Journal: Nature biotechnology 20050101

Title: Peptide-specific intercellular transfer of MHC class II to CD4+ T cells directly from the immunological synapse upon cellular dissociation.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20050101

Title: Fully automated synthesis of (phospho)peptide arrays in microtiter plate wells provides efficient access to protein tyrosine kinase characterization.

Journal: BMC immunology 20050101

Title: Inflammation and carnitine in hemodialysis patients.

Journal: Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20050101

Title: Phosphoprotein profiling of erythropoietin receptor- dependent pathways using different proteomic strategies.

Journal: Proteomics 20050101

Title: Novel hepatocyte growth factor (HGF) binding domains on fibronectin and vitronectin coordinate a distinct and amplified Met-integrin induced signalling pathway in endothelial cells.

Journal: BMC cell biology 20050101

Title: Phosphoproteomic analysis using immobilized metal ion affinity chromatography on the basis of cellulose powder.

Journal: Proteomics 20050101

Title: Tyrosine phosphorylation of myosin heavy chain during skeletal muscle differentiation: an integrated bioinformatics approach.

Journal: Theoretical biology & medical modelling 20050101

Title: Local delivery of soluble interleukin-6 receptors to improve the outcome of alpha-toxin producing Staphylococcus aureus infection in mice.

Journal: Immunobiology 20050101

Title: Action of fenretinide (4-HPR) on ovarian cancer and endothelial cells.

Journal: Anticancer research 20050101

Title: A novel EB-1/AIDA-1 isoform, AIDA-1c, interacts with the Cajal body protein coilin.

Journal: BMC cell biology 20050101

Title: Hyperglycemia potentiates H(2)O(2) production in adipocytes and enhances insulin signal transduction: potential role for oxidative inhibition of thiol-sensitive protein-tyrosine phosphatases.

Journal: Antioxidants & redox signaling 20050101

Title: Anchorage-dependent cell growth: tyrosine kinases and phosphatases meet redox regulation.

Journal: Antioxidants & redox signaling 20050101

Title: The integrins of the urochordate Ciona intestinalis provide novel insights into the molecular evolution of the vertebrate integrin family.

Journal: BMC evolutionary biology 20050101

Title: Possible active origin of replication in the double stranded extended form of the left terminus of LuIII and its implication on the replication model of the parvovirus.

Journal: Virology journal 20050101

Title: 14-3-3 protein signaling in development and growth factor responses.

Journal: Current topics in developmental biology 20050101

Title: The proacrosin binding protein, sp32, is tyrosine phosphorylated during capacitation of pig sperm.

Journal: Journal of andrology 20050101

Title: Regulation of mouse hepatic genes in response to diet induced obesity, insulin resistance and fasting induced weight reduction.

Journal: Nutrition & metabolism 20050101

Title: H2O2-induced phosphorylation of ERK1/2 and PKB requires tyrosine kinase activity of insulin receptor and c-Src.

Journal: Antioxidants & redox signaling 20050101

Title: Role of insulin-induced reactive oxygen species in the insulin signaling pathway.

Journal: Antioxidants & redox signaling 20050101

Title: Global gene expression analysis in time series following N-acetyl L-cysteine induced epithelial differentiation of human normal and cancer cells in vitro.

Journal: BMC cancer 20050101

Title: Relative quantification of erythropoietin receptor-dependent phosphoproteins using in-gel 18O-labeling and tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20050101

Title: Early-stage folding in proteins (in silico) sequence-to-structure relation.

Journal: Journal of biomedicine & biotechnology 20050101

Title: Spinal cord NR1 serine phosphorylation and NR2B subunit suppression following peripheral inflammation.

Journal: Molecular pain 20050101

Title: Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi.

Journal: BMC genomics 20050101

Title: Phosphoproteomics: new insights into cellular signaling.

Journal: Genome biology 20050101

Title: Differential responses to doxorubicin-induced phosphorylation and activation of Akt in human breast cancer cells.

Journal: Breast cancer research : BCR 20050101

Title: Construction and validation of a Bovine Innate Immune Microarray.

Journal: BMC genomics 20050101

Title: Activation of focal adhesion kinase enhances the adhesion and invasion of pancreatic cancer cells via extracellular signal-regulated kinase-1/2 signaling pathway activation.

Journal: Molecular cancer 20050101

Title: The novel protein KBP regulates mitochondria localization by interaction with a kinesin-like protein.

Journal: BMC cell biology 20050101

Title: Mapping and characterization of the amplicon near APOA2 in 1q23 in human sarcomas by FISH and array CGH.

Journal: Molecular cancer 20050101

Title: E3 ubiquitin ligases and their control of T cell autoreactivity.

Journal: Arthritis research & therapy 20050101

Title: Peroxynitrite-dependent upregulation of SRC kinases in red blood cells: strategies to study the activation mechanisms.

Journal: Methods in enzymology 20050101

Title: FGF receptor phosphotyrosine 766 is a target for Grb14 to inhibit MDA-MB-231 human breast cancer cell signaling.

Journal: Anticancer research 20050101

Title: Protein kinase activity is associated with CD63 in melanoma cells.

Journal: Journal of translational medicine 20050101

Title: A neural strategy for the inference of SH3 domain-peptide interaction specificity.

Journal: BMC bioinformatics 20050101

Title: C/EBPbeta-2 confers EGF-independent growth and disrupts the normal acinar architecture of human mammary epithelial cells.

Journal: Molecular cancer 20050101

Title: Phosphate isosteres in medicinal chemistry.

Journal: Current medicinal chemistry 20050101

Title: A new tyrosine phosphorylation mechanism involved in signal transduction in Bacillus subtilis.

Journal: Journal of molecular microbiology and biotechnology 20050101

Title: Protein-tyrosine phosphorylation in Bacillus subtilis.

Journal: Journal of molecular microbiology and biotechnology 20050101

Title: Interaction between the Yersinia tyrosine phosphatase YopH and its macrophage substrate, Fyn-binding protein, Fyb.

Journal: Journal of molecular microbiology and biotechnology 20050101

Title: Inhibition of CCN6 (WISP3) expression promotes neoplastic progression and enhances the effects of insulin-like growth factor-1 on breast epithelial cells.

Journal: Breast cancer research : BCR 20050101

Title: Tyrosine phosphorylation of Rab proteins.

Journal: Methods in enzymology 20050101

Title: During muscle ageing the activation of the mitogenic signalling is not sufficient to guarantee cellular duplication.

Journal: The Italian journal of biochemistry 20050101

Title: Phosphotyrosine interactome of the ErbB-receptor kinase family.

Journal: Molecular systems biology 20050101

Title: A comprehensive pathway map of epidermal growth factor receptor signaling.

Journal: Molecular systems biology 20050101

Title: Ribonucleopeptides recognize the phosphotyrosine residue.

Journal: Nucleic acids symposium series (2004) 20050101

Title: Ubiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitment.

Journal: The Journal of biological chemistry 20041231

Title: Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen.

Journal: The Journal of biological chemistry 20041224

Title: Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of toll-like receptor signaling.

Journal: The Journal of biological chemistry 20041224

Title: Phospholipase D1 regulates high-affinity IgE receptor-induced mast cell degranulation.

Journal: Blood 20041215

Title: Distinctive activation mechanisms and functions for protein kinase Cdelta.

Journal: The Biochemical journal 20041215

Title: dPak is required for integrity of the leading edge cytoskeleton during Drosophila dorsal closure but does not signal through the JNK cascade.

Journal: Developmental biology 20041215

Title: Retinoids arrest breast cancer cell proliferation: retinoic acid selectively reduces the duration of receptor tyrosine kinase signaling.

Journal: Experimental cell research 20041210

Title: A nonhydrolyzable analogue of phosphotyrosine, and related aryloxymethano- and aryloxyethano-phosphonic acids as motifs for inhibition of phosphatases.

Journal: Bioorganic & medicinal chemistry letters 20041206

Title: Implication of cAMP during porcine sperm capacitation and protein tyrosine phosphorylation.

Journal: Molecular reproduction and development 20041201

Title: A cyclic adenosine 3',5'-monophosphate-induced tyrosine phosphorylation of Syk protein tyrosine kinase in the flagella of boar spermatozoa.

Journal: Molecular reproduction and development 20041201

Title: Immunohistochemical analysis of tyrosine phosphorylation and AP-1 transcription factors c-Jun, Jun D, and Fos family during early ovarian follicle development in the mouse.

Journal: Applied immunohistochemistry & molecular morphology : AIMM 20041201

Title: Correlation between tyrosine phosphorylation intensity of a 107 kDa protein band and A23187-induced acrosome reaction in human spermatozoa.

Journal: Andrologia 20041201

Title: IREM-1 is a novel inhibitory receptor expressed by myeloid cells.

Journal: European journal of immunology 20041201

Title: Role of ErbB2 in Corneal Epithelial Wound Healing.

Journal: Investigative ophthalmology & visual science 20041201

Title: Nitric oxide block of outward-rectifying K+ channels indicates direct control by protein nitrosylation in guard cells.

Journal: Plant physiology 20041201

Title: Mapping netrin receptor binding reveals domains of Unc5 regulating its tyrosine phosphorylation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041201

Title: Mechanisms of resistance to Erbitux (anti-epidermal growth factor receptor) combination therapy in pancreatic adenocarcinoma cells.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20041201

Title: Thrombopoietin regulates proliferation, apoptosis, secretory activity and intracellular messengers in porcine ovarian follicular cells: involvement of protein kinase A.

Journal: The Journal of endocrinology 20041201

Title: The phosphotyrosine phosphatase eta mediates somatostatin inhibition of glioma proliferation via the dephosphorylation of ERK1/2.

Journal: Annals of the New York Academy of Sciences 20041201

Title: Activation of signal transducer and activator of transcription 5 (STAT5) in splenocyte proliferation of asthma mice induced by ovalbumin.

Journal: Cellular & molecular immunology 20041201

Title: Characterization of Lck-binding elements in the herpesviral regulatory Tip protein.

Journal: Biochemistry 20041130

Title: Src protein-tyrosine kinase structure and regulation.

Journal: Biochemical and biophysical research communications 20041126

Title: TMF/ARA160 is a BC-box-containing protein that mediates the degradation of Stat3.

Journal: Oncogene 20041125

Title: Mechanisms involved in the blood-brain barrier increased permeability induced by Phoneutria nigriventer spider venom in rats.

Journal: Brain research 20041119

Title: Tyrosine phosphorylation of caveolin-2 at residue 27: differences in the spatial and temporal behavior of phospho-Cav-2 (pY19 and pY27).

Journal: Biochemistry 20041102

Title: IL-6-induced survival of colorectal carcinoma cells is inhibited by butyrate through down-regulation of the IL-6 receptor.

Journal: Carcinogenesis 20041101

Title: Deletion of the pleckstrin and phosphotyrosine binding domains of insulin receptor substrate-2 does not impair its ability to regulate cell proliferation in myeloid cells.

Journal: Endocrinology 20041101

Title: A prototype antibody microarray platform to monitor changes in protein tyrosine phosphorylation.

Journal: Molecular & cellular proteomics : MCP 20041101

Title: Rapid detection of phosphotyrosine proteins by flow cytometric analysis in Bcr-Abl-positive cells.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20041101

Title: Modulation of Erbb2 signaling during development: a threshold level of Erbb2 signaling is required for development.

Journal: Development (Cambridge, England) 20041101

Title: From modulator to mediator: rapid effects of BDNF on ion channels.

Journal: BioEssays : news and reviews in molecular, cellular and developmental biology 20041101

Title: Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes.

Journal: Diabetes 20041101

Title: Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study.

Journal: Diabetes 20041101

Title: Expression of FGF-2 alters focal adhesion dynamics in migration-restricted MDA-MB-231 breast cancer cells.

Journal: Breast cancer research and treatment 20041101

Title: Development of a polyvalent assay system for lead identification.

Journal: Bioorganic & medicinal chemistry letters 20041018

Title: Structure and regulation of Src family kinases.

Journal: Oncogene 20041018

Title: Inhibition of wild-type and mutant Bcr-Abl by AP23464, a potent ATP-based oncogenic protein kinase inhibitor: implications for CML.

Journal: Blood 20041015

Title: Loss of SHIP and CIS recruitment to the granulocyte colony-stimulating factor receptor contribute to hyperproliferative responses in severe congenital neutropenia/acute myelogenous leukemia.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20041015

Title: The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway.

Journal: Oncogene 20041014

Title: Alpha2-chimaerin, cyclin-dependent Kinase 5/p35, and its target collapsin response mediator protein-2 are essential components in semaphorin 3A-induced growth-cone collapse.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041013

Title: X-ray crystal structure of the hypothetical phosphotyrosine phosphatase MDP-1 of the haloacid dehalogenase superfamily.

Journal: Biochemistry 20041012

Title: Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes.

Journal: American journal of respiratory cell and molecular biology 20041001

Title: Characterization of two distinct dual specificity phosphatases encoded in alternative open reading frames of a single gene located on human chromosome 10q22.2.

Journal: The Journal of biological chemistry 20041001

Title: Alternative activation of STAT1 and STAT3 in response to interferon-gamma.

Journal: The Journal of biological chemistry 20041001

Title: SRC mediates a switch from microtubule- to actin-based motility of vaccinia virus.

Journal: Science (New York, N.Y.) 20041001

Title: The efficiency of mispaired ligations by lambda integrase is extremely sensitive to context.

Journal: Journal of molecular biology 20041001

Title: Inhibition of serum-stimulated mitogen activated protein kinase by 1alpha,25(OH)2-vitamin D3 in MCF-7 breast cancer cells.

Journal: Journal of cellular biochemistry 20041001

Title: Enhanced expression of adaptor molecule p46 Shc in nuclei of hepatocellular carcinoma cells: study of LEC rats.

Journal: International journal of oncology 20041001

Title: Insulin resistance in thermally-injured rats is associated with post-receptor alterations in skeletal muscle, liver and adipose tissue.

Journal: International journal of molecular medicine 20041001

Title: Enhancement of insulin signaling through inhibition of tissue lipid accumulation by activation of peroxisome proliferator-activated receptor (PPAR) alpha in obese mice.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20041001

Title: Cytoplasmic tail adaptors of Alzheimer's amyloid-beta protein precursor.

Journal: Molecular neurobiology 20041001

Title: Increased expression of focal adhesion kinase in thyroid cancer: immunohistochemical study.

Journal: Journal of Korean medical science 20041001

Title: An improved method for utilization of peptide substrates for antibody characterization and enzymatic assays.

Journal: Journal of immunological methods 20041001

Title: Inhibitors for proteins endowed with catalytic and non-catalytic activity which recognize pTyr.

Journal: Current medicinal chemistry 20041001

Title: Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.

Journal: The Journal of biological chemistry 20040924

Title: CAS promotes invasiveness of Src-transformed cells.

Journal: Oncogene 20040923

Title: Hypotonicity-induced exocytosis of the skate anion exchanger skAE1: role of lipid raft regions.

Journal: The Journal of biological chemistry 20040917

Title: Mild impairment of motor nerve repair in mice lacking PTP-BL tyrosine phosphatase activity.

Journal: Physiological genomics 20040916

Title: Proteomic analysis of phosphotyrosyl proteins in the rat brain: effect of butorphanol dependence.

Journal: Journal of neuroscience research 20040915

Title: Long-lasting rescue of age-associated deficits in cognition and the CNS cholinergic phenotype by a partial agonist peptidomimetic ligand of TrkA.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040915

Title: Recombinant humanised anti-HER2/neu antibody (Herceptin) induces cellular death of glioblastomas.

Journal: British journal of cancer 20040913

Title: Sustained antiproliferative mechanisms by RB24, a targeted precursor of multiple inhibitors of epidermal growth factor receptor and a DNA alkylating agent in the A431 epidermal carcinoma of the vulva cell line.

Journal: British journal of cancer 20040913

Title: Tyrosine phosphorylation, thiol status, and protein tyrosine phosphatase in rat epididymal spermatozoa.

Journal: Biology of reproduction 20040901

Title: IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells.

Journal: The Journal of pharmacology and experimental therapeutics 20040901

Title: Characterization of protein tyrosine phosphatase activity in rat liver microsomes: suppressive effect of endogenous regucalcin in transgenic rats.

Journal: International journal of molecular medicine 20040901

Title: Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics.

Journal: Nature biotechnology 20040901

Title: Solution structure of the human Grb14-SH2 domain and comparison with the structures of the human Grb7-SH2/erbB2 peptide complex and human Grb10-SH2 domain.

Journal: Protein science : a publication of the Protein Society 20040901

Title: Control of vesicle fusion by a tyrosine phosphatase.

Journal: Nature cell biology 20040901

Title: The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanisms.

Journal: PLoS biology 20040901

Title: Water-molecule network and active-site flexibility of apo protein tyrosine phosphatase 1B.

Journal: Acta crystallographica. Section D, Biological crystallography 20040901

Title: Phosphoproteomics finds its timing.

Journal: Nature biotechnology 20040901

Title: Apoptotic cell death influences the signaling activity of the amyloid precursor protein through ShcA and Grb2 adaptor proteins in neuroblastoma SH-SY5Y cells.

Journal: Journal of neurochemistry 20040901

Title: The identification of Dictyostelium phosphoproteins altered in response to the activation of RasG.

Journal: Proteomics 20040901

Title: Reduced plasma membrane Ca2+-ATPase function in platelets from patients with non-insulin-dependent diabetes mellitus.

Journal: Haematologica 20040901

Title: The dual-function disabled-1 PTB domain exhibits site independence in binding phosphoinositide and peptide ligands.

Journal: Biochemistry 20040831

Title: Mouse embryonic fibroblasts derived from Odin deficient mice display a hyperproliiferative phenotype.

Journal: DNA research : an international journal for rapid publication of reports on genes and genomes 20040831

Title: Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiation.

Journal: The Journal of biological chemistry 20040827

Title: Imaging phosphorylation dynamics of the epidermal growth factor receptor.

Journal: The Journal of biological chemistry 20040827

Title: Sustained stimulation of platelet thrombin receptor is associated with tyrosine dephosphorylation of a novel p67 peptide in a manner regulated by extracellular calcium.

Journal: Biochimica et biophysica acta 20040823

Title: The in vivo tyrosine phosphorylation level of yeast immunophilin Fpr3 is influenced by the LMW-PTP Ltp1.

Journal: Biochemical and biophysical research communications 20040820

Title: MUC1 tyrosine phosphorylation activates the extracellular signal-regulated kinase.

Journal: Biochemical and biophysical research communications 20040820

Title: LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation.

Journal: The EMBO journal 20040818

Title: Dual blockade of EGFR and ERK1/2 phosphorylation potentiates growth inhibition of breast cancer cells.

Journal: British journal of cancer 20040816

Title: Upregulation of the transcript level of GTPase activating protein KIAA0603 in T cells from patients with atopic dermatitis.

Journal: FEBS letters 20040813

Title: Molecular cloning and characterization of a novel dual-specificity phosphatase 23 gene from human fetal brain.

Journal: The international journal of biochemistry & cell biology 20040801

Title: Prosaposin: a new player in cell death prevention of U937 monocytic cells.

Journal: Experimental cell research 20040801

Title: Complexes of gamma-tubulin with nonreceptor protein tyrosine kinases Src and Fyn in differentiating P19 embryonal carcinoma cells.

Journal: Experimental cell research 20040801

Title: Analysis of Chlamydia caviae entry sites and involvement of Cdc42 and Rac activity.

Journal: Journal of cell science 20040801

Title: Role of EGFR transactivation in preventing apoptosis in Pseudomonas aeruginosa-infected human corneal epithelial cells.

Journal: Investigative ophthalmology & visual science 20040801

Title: EspFU is a translocated EHEC effector that interacts with Tir and N-WASP and promotes Nck-independent actin assembly.

Journal: Developmental cell 20040801

Title: Finding functional sites in structural genomics proteins.

Journal: Structure (London, England : 1993) 20040801

Title: Characterization of dynamic and steady-state protein phosphorylation using a fluorescent phosphoprotein gel stain and mass spectrometry.

Journal: Electrophoresis 20040801

Title: IFN-alpha5 mediates stronger Tyk2-stat-dependent activation and higher expression of 2',5'-oligoadenylate synthetase than IFN-alpha2 in liver cells.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20040801

Title: Development of a quantitative, high-throughput cell-based enzyme-linked immunosorbent assay for detection of colony-stimulating factor-1 receptor tyrosine kinase inhibitors.

Journal: Journal of biochemical and biophysical methods 20040730

Title: Tracing kinetic intermediates during ligand binding.

Journal: Journal of the American Chemical Society 20040728

Title: Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation.

Journal: The Journal of biological chemistry 20040716

Title: Tyrosine phosphorylation activates surface chaperones facilitating sperm-zona recognition.

Journal: Journal of cell science 20040715

Title: Probing the transition-state structure of dual-specificity protein phosphatases using a physiological substrate mimic.

Journal: Biochemistry 20040713

Title: The expression of the phosphotyrosine phosphatase DEP-1/PTPeta dictates the responsivity of glioma cells to somatostatin inhibition of cell proliferation.

Journal: The Journal of biological chemistry 20040709

Title: Identification of the linker-SH2 domain of STAT as the origin of the SH2 domain using two-dimensional structural alignment.

Journal: Molecular & cellular proteomics : MCP 20040701

Title: Cross-linking of MHC class I molecules on human NK cells inhibits NK cell function, segregates MHC I from the NK cell synapse, and induces intracellular phosphotyrosines.

Journal: Journal of leukocyte biology 20040701

Title: Early molecular events in the assembly of the focal adhesion-stress fiber complex during fibroblast spreading.

Journal: Cell motility and the cytoskeleton 20040701

Title: A method for simultaneous alignment of multiple protein structures.

Journal: Proteins 20040701

Title: Epidermal growth factor stimulation of RPE cell survival: contribution of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways.

Journal: Experimental eye research 20040701

Title: A high-throughput fluorescence polarization assay for signal transducer and activator of transcription 3.

Journal: Analytical biochemistry 20040701

Title: TFIIH contains a PH domain involved in DNA nucleotide excision repair.

Journal: Nature structural & molecular biology 20040701

Title: Tyrosine phosphorylation of calponins. Inhibition of the interaction with F-actin.

Journal: European journal of biochemistry 20040701

Title: Changes in structural dynamics of the Grb2 adaptor protein upon binding of phosphotyrosine ligand to its SH2 domain.

Journal: Biochimica et biophysica acta 20040701

Title: Identification of non-phosphate-containing small molecular weight inhibitors of the tyrosine kinase p56 Lck SH2 domain via in silico screening against the pY + 3 binding site.

Journal: Journal of medicinal chemistry 20040701

Title: Singlet oxygen-induced attenuation of growth factor signaling: possible role of ceramides.

Journal: Free radical research 20040701

Title: Development of l-3-aminotyrosine suitably protected for the synthesis of a novel nonphosphorylated hexapeptide with low-nanomolar Grb2-SH2 domain-binding affinity.

Journal: Bioorganic & medicinal chemistry letters 20040621

Title: Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors.

Journal: Blood 20040615

Title: Human marrow stromal cells activate monocytes to secrete osteopontin, which down-regulates Notch1 gene expression in CD34+ cells.

Journal: Blood 20040615

Title: p120 Ras GTPase-activating protein associates with fibroblast growth factor receptors in Drosophila.

Journal: The Biochemical journal 20040615

Title: The ErbB signaling network is coordinately expressed and activated in the mouse prostate.

Journal: The Prostate 20040615

Title: A proteomic approach to identify phosphoproteins encoded by cDNA libraries.

Journal: Analytical biochemistry 20040615

Title: Gene expression profiles in an hepatitis B virus transfected hepatoblastoma cell line and differentially regulated gene expression by interferon-alpha.

Journal: World journal of gastroenterology 20040615

Title: Selective tyrosine hyperphosphorylation of cytoskeletal and stress proteins in primary human breast cancers: implications for adjuvant use of kinase-inhibitory drugs.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040615

Title: Growth factor receptor-bound protein 2 interaction with the tyrosine-phosphorylated tail of amyloid beta precursor protein is mediated by its Src homology 2 domain.

Journal: The Journal of biological chemistry 20040611

Title: Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action.

Journal: The Journal of biological chemistry 20040604

Title: Actin depolymerization-induced tyrosine phosphorylation of cortactin: the role of Fer kinase.

Journal: The Biochemical journal 20040601

Title: Isolation and partial characterisation of acid phosphatase isozymes from dormant oilseed of Corylus avellana L.

Journal: Planta 20040601

Title: Activation and inhibition of cyclin-dependent kinase-2 by phosphorylation; a molecular dynamics study reveals the functional importance of the glycine-rich loop.

Journal: Protein science : a publication of the Protein Society 20040601

Title: Exacerbated graft-versus-host disease in Pirb-/- mice.

Journal: Nature immunology 20040601

Title: Ca(2+)-sensitive tyrosine kinase Pyk2/CAK beta-dependent signaling is essential for G-protein-coupled receptor agonist-induced hypertrophy.

Journal: Journal of molecular and cellular cardiology 20040601

Title: Cytoplasmic p120ctn regulates the invasive phenotypes of E-cadherin-deficient breast cancer.

Journal: The American journal of pathology 20040601

Title: Regulation of haematopoiesis by growth factors - emerging insights and therapies.

Journal: Expert opinion on biological therapy 20040601

Title: Growth hormone (GH) receptors in prostate cancer: gene expression in human tissues and cell lines and characterization, GH signaling and androgen receptor regulation in LNCaP cells.

Journal: Molecular and cellular endocrinology 20040531

Title: Temporal dissection of beta1-integrin signaling indicates a role for p130Cas-Crk in filopodia formation.

Journal: The Journal of biological chemistry 20040528

Title: The low density lipoprotein receptor-related protein is a motogenic receptor for plasminogen activator inhibitor-1.

Journal: The Journal of biological chemistry 20040521

Title: The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration.

Journal: The Journal of biological chemistry 20040521

Title: The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65/amyloid precursor protein nuclear signaling.

Journal: The Journal of biological chemistry 20040521

Title: Tyrosine phosphorylated Disabled 1 recruits Crk family adapter proteins.

Journal: Biochemical and biophysical research communications 20040521

Title: SRC-dependent outside-in signalling is a key step in the process of autoregulation of beta2 integrins in polymorphonuclear cells.

Journal: The Biochemical journal 20040515

Title: A novel 110 kDa form of myosin XVIIIA (MysPDZ) is tyrosine-phosphorylated after colony-stimulating factor-1 receptor signalling.

Journal: The Biochemical journal 20040515

Title: The aryl hydrocarbon receptor (AhR) tyrosine 9, a residue that is essential for AhR DNA binding activity, is not a phosphoresidue but augments AhR phosphorylation.

Journal: The Journal of biological chemistry 20040514

Title: Critical role for hematopoietic cell kinase (Hck)-mediated phosphorylation of Gab1 and Gab2 docking proteins in interleukin 6-induced proliferation and survival of multiple myeloma cells.

Journal: The Journal of biological chemistry 20040514

Title: Primary and essential role of the adaptor protein APS for recruitment of both c-Cbl and its associated protein CAP in insulin signaling.

Journal: The Journal of biological chemistry 20040514

Title: Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells.

Journal: Circulation research 20040514

Title: SH3P2 in complex with Cbl and Src.

Journal: FEBS letters 20040507

Title: Electrochemistry/mass spectrometry (EC/MS)--a new tool to study drug metabolism and reaction mechanisms.

Journal: Angewandte Chemie (International ed. in English) 20040503

Title: Regulation and localization of CAS substrate domain tyrosine phosphorylation.

Journal: Cellular signalling 20040501

Title: Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.

Journal: The Biochemical journal 20040501

Title: Characterization of the interactions of estrogen receptor and MNAR in the activation of cSrc.

Journal: Molecular endocrinology (Baltimore, Md.) 20040501

Title: Alterations of cell signaling pathways in pancreatic cancer.

Journal: Frontiers in bioscience : a journal and virtual library 20040501

Title: Phosphotyrosine phosphatases acting on band 3 in human erythrocytes of different age: PTP1B processing during cell ageing.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20040501

Title: Identification of p46 Shc expressed in the nuclei of hepatocytes with high proliferating activity: Study of regenerating rat liver.

Journal: International journal of molecular medicine 20040501

Title: Tyrosine phosphorylation of NOS3 in a breast cancer cell line and Src-transformed cells.

Journal: Oncology reports 20040501

Title: A quantum mechanical study on phosphotyrosyl peptide binding to the SH2 domain of p56lck tyrosine kinase with insights into the biochemistry of intracellular signal transduction events.

Journal: Biophysical chemistry 20040501

Title: MERTK arginine-844-cysteine in a patient with severe rod-cone dystrophy: loss of mutant protein function in transfected cells.

Journal: Investigative ophthalmology & visual science 20040501

Title: Angiotensin II stimulates cAMP production and protein tyrosine phosphorylation in mouse spermatozoa.

Journal: Reproduction (Cambridge, England) 20040501

Title: Focal adhesion and actin dynamics: a place where kinases and proteases meet to promote invasion.

Journal: Trends in cell biology 20040501

Title: Increasing neutrophil F-actin corrects CD11b exposure in Type 2 diabetes.

Journal: European journal of clinical investigation 20040501

Title: American Chemical Society--227th annual meeting. Diabetes. 28 March - 1 April 2004, Anaheim, CA, USA.

Journal: IDrugs : the investigational drugs journal 20040501

Title: Dietary branched-chain amino acids suppress the expression of pancreatic amylase mRNA in rats.

Journal: Bioscience, biotechnology, and biochemistry 20040501

Title: Proteomic approach to the identification of voltage-dependent anion channel protein isoforms in guinea pig brain synaptosomes.

Journal: Proteomics 20040501

Title: Pleckstrin homology and phosphotyrosine-binding domain-dependent membrane association and tyrosine phosphorylation of Dok-4, an inhibitory adapter molecule expressed in epithelial cells.

Journal: The Journal of biological chemistry 20040430

Title: Structural requirements for signal transducer and activator of transcription 3 binding to phosphotyrosine ligands containing the YXXQ motif.

Journal: The Journal of biological chemistry 20040430

Title: A single residue modulates tyrosine dephosphorylation, oligomerization, and nuclear accumulation of stat transcription factors.

Journal: The Journal of biological chemistry 20040430

Title: Alternative splicing modulates Disabled-1 (Dab1) function in the developing chick retina.

Journal: The EMBO journal 20040421

Title: Adhesion-dependent regulation of p190RhoGAP in the developing brain by the Abl-related gene tyrosine kinase.

Journal: Current biology : CB 20040420

Title: Phosphotyrosyl peptides and analogues as substrates and inhibitors of purple acid phosphatases.

Journal: Archives of biochemistry and biophysics 20040415

Title: Tyrosine phosphorylation of the Janus kinase 2 activation loop is essential for a high-activity catalytic state but dispensable for a basal catalytic state.

Journal: Biochemistry 20040413

Title: Catalytic inactivation of protein tyrosine phosphatase CD45 and protein tyrosine phosphatase 1B by polyaromatic quinones.

Journal: Biochemistry 20040413

Title: Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia.

Journal: The Journal of biological chemistry 20040409

Title: Identification of RET autophosphorylation sites by mass spectrometry.

Journal: The Journal of biological chemistry 20040402

Title: Galectin-1 induces astrocyte differentiation, which leads to production of brain-derived neurotrophic factor.

Journal: Glycobiology 20040401

Title: Protein kinase C modulates negatively the hepatocyte growth factor-induced migration, integrin expression and phosphatidylinositol 3-kinase activation.

Journal: Cellular signalling 20040401

Title: Leptin increases cardiomyocyte hyperplasia via extracellular signal-regulated kinase- and phosphatidylinositol 3-kinase-dependent signaling pathways.

Journal: Endocrinology 20040401

Title: The first green lineage cdc25 dual-specificity phosphatase.

Journal: Cell cycle (Georgetown, Tex.) 20040401

Title: Laminin-2 stimulates the proliferation of epithelial cells in a conjunctival epithelial cell line.

Journal: Cell proliferation 20040401

Title: The development of signal transduction pathways during epididymal maturation is calcium dependent.

Journal: Developmental biology 20040401

Title: Identification of apoptotic tyrosine-phosphorylated proteins after etoposide or retinoic acid treatment.

Journal: Proteomics 20040401

Title: Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects.

Journal: Cancer research 20040401

Title: SH2 domains in plants imply new signalling scenarios.

Journal: Trends in plant science 20040401

Title: The role of calcium, calcium-activated K+ channels, and tyrosine/kinase in psoralen-evoked responses in human melanoma cells.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040401

Title: A homogeneous, nonradioactive high-throughput fluorogenic protein phosphatase assay.

Journal: Journal of biomolecular screening 20040401

Title: Epidermal growth factor modulates tyrosine phosphorylation of a novel tensin family member, tensin3.

Journal: Molecular cancer research : MCR 20040401

Title: [Phosphotyrosine phosphatase SHP-1, somatostatin and prostate cancer].

Journal: Actas urologicas espanolas 20040401

Title: Vascular endothelial cadherin and beta-catenin in human fetoplacental vessels of pregnancies complicated by Type 1 diabetes: associations with angiogenesis and perturbed barrier function.

Journal: Diabetologia 20040401

Title: Two-dimensional diversity: screening human cDNA phage display libraries with a random diversity probe for the display cloning of phosphotyrosine binding domains.

Journal: Journal of the American Chemical Society 20040331

Title: Effective dephosphorylation of Src substrates by SHP-1.

Journal: The Journal of biological chemistry 20040319

Title: Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases.

Journal: Oncogene 20040315

Title: Participation of p97Eps8 in Src-mediated transformation.

Journal: The Journal of biological chemistry 20040312

Title: Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD.

Journal: The EMBO journal 20040310

Title: Localization of Tec29 to ring canals is mediated by Src64 and PtdIns(3,4,5)P3-dependent mechanisms.

Journal: The EMBO journal 20040310

Title: Mechanism of platelet-derived growth factor-dependent caveolin-1 phosphorylation: relationship to sterol binding and the role of serine-80.

Journal: Biochemistry 20040309

Title: Regulation of the neuronal nicotinic acetylcholine receptor by SRC family tyrosine kinases.

Journal: The Journal of biological chemistry 20040305

Title: Cbl-c suppresses v-Src-induced transformation through ubiquitin-dependent protein degradation.

Journal: Oncogene 20040304

Title: Residue 182 influences the second step of protein-tyrosine phosphatase-mediated catalysis.

Journal: The Biochemical journal 20040301

Title: Upregulation of mRNA in MAPK signaling: transcriptional activation or mRNA stabilization?

Journal: Cell cycle (Georgetown, Tex.) 20040301

Title: Wound-induced HB-EGF ectodomain shedding and EGFR activation in corneal epithelial cells.

Journal: Investigative ophthalmology & visual science 20040301

Title: Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity.

Journal: Molecular cancer therapeutics 20040301

Title: Tensin stabilizes integrin adhesive contacts in Drosophila.

Journal: Developmental cell 20040301

Title: AlphaScreen kinase HTS platforms.

Journal: Current medicinal chemistry 20040301

Title: Use of high affinity insulin analogues to assess the functional relationships between insulin receptor trafficking, mitogenic signaling and mRNA expression in rat liver.

Journal: Biochimie 20040301

Title: The adaptor disabled-2 binds to the third psi xNPxY sequence on the cytoplasmic tail of megalin.

Journal: Biochimie 20040301

Title: A boy with autosomal recessive hypercholesterolaemia.

Journal: The Netherlands journal of medicine 20040301

Title: Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor.

Journal: The Journal of biological chemistry 20040227

Title: Structure-activity relationships of small phosphopeptides, inhibitors of Grb2 SH2 domain, and their prodrugs.

Journal: Journal of medicinal chemistry 20040226

Title: A highly conserved NTRK3 C-terminal sequence in the ETV6-NTRK3 oncoprotein binds the phosphotyrosine binding domain of insulin receptor substrate-1: an essential interaction for transformation.

Journal: The Journal of biological chemistry 20040220

Title: Structural basis for the specific recognition of RET by the Dok1 phosphotyrosine binding domain.

Journal: The Journal of biological chemistry 20040206

Title: Improved biocompatibility of small intestinal submucosa (SIS) following conditioning by human endothelial cells.

Journal: Biomaterials 20040201

Title: IL-7 induces tyrosine phosphorylation of clathrin heavy chain.

Journal: Cellular signalling 20040201

Title: S1P3-mediated Akt activation and cross-talk with platelet-derived growth factor receptor (PDGFR).

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040201

Title: Overexpression of profilin reduces the migration of invasive breast cancer cells.

Journal: Cell motility and the cytoskeleton 20040201

Title: A zinc-binding dual-specificity YVH1 phosphatase in the malaria parasite, Plasmodium falciparum, and its interaction with the nuclear protein, pescadillo.

Journal: Molecular and biochemical parasitology 20040201

Title: Phosphotyrosine phosphoepitopes can be rapidly analyzed by coexpression of a tyrosine kinase in bacteria with a T7 bacteriophage display library.

Journal: Analytical biochemistry 20040201

Title: Suppressive effect of regucalcin on protein phosphatase activity in the heart cytosol of normal and regucalcin transgenic rats.

Journal: International journal of molecular medicine 20040201

Title: Cyclic AMP-dependent tyrosine phosphorylation in tammar wallaby (Macropus eugenii) spermatozoa.

Journal: Journal of experimental zoology. Part A, Comparative experimental biology 20040201

Title: X11alpha impairs gamma- but not beta-cleavage of amyloid precursor protein.

Journal: Journal of neurochemistry 20040201

Title: Inactivation of Stat3 in tumor cells: releasing a brake on immune responses against cancer?

Journal: Cancer cell 20040201

Title: Antipsoriatic drug anthralin induces EGF receptor phosphorylation in keratinocytes: requirement for H(2)O(2) generation.

Journal: Experimental dermatology 20040201

Title: Effect of a Korean traditional formulation, Hwaotang, on superoxide generation in human neutrophils, platelet aggregation in human blood, and nitric oxide, prostaglandin E2 production and paw oedema induced by carrageenan in mice.

Journal: Immunopharmacology and immunotoxicology 20040201

Title: Preparation and application of polyclonal and monoclonal sequence-specific anti-phosphoamino acid antibodies.

Journal: Current protocols in protein science 20040201

Title: Subdomain X of the kinase domain of Lck binds CD45 and facilitates dephosphorylation.

Journal: The Journal of biological chemistry 20040130

Title: Negative regulation of ErbB family receptor tyrosine kinases.

Journal: British journal of cancer 20040126

Title: Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems.

Journal: Cell 20040123

Title: A cryptic targeting signal induces isoform-specific localization of p46Shc to mitochondria.

Journal: The Journal of biological chemistry 20040116

Title: Tyrosine phosphorylation of BIT on photic stimulation in the rat retina.

Journal: FEBS letters 20040116

Title: Differential sorting of tyrosine kinases and phosphotyrosine phosphatases acting on band 3 during vesiculation of human erythrocytes.

Journal: The Biochemical journal 20040115

Title: Analysis of the mechanism by which calcium negatively regulates the tyrosine phosphorylation cascade associated with sperm capacitation.

Journal: Journal of cell science 20040115

Title: Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38.

Journal: Oncogene 20040115

Title: Regulation of the dual specificity protein phosphatase, DsPTP1, through interactions with calmodulin.

Journal: The Journal of biological chemistry 20040109

Title: Contribution of the membrane-distal tyrosine in intracellular signaling by the granulocyte colony-stimulating factor receptor.

Journal: The Journal of biological chemistry 20040102

Title: Probing protein-tyrosine phosphatase substrate specificity using a phosphotyrosine-containing phage library.

Journal: The Journal of biological chemistry 20040102

Title: Tensin.

Journal: The international journal of biochemistry & cell biology 20040101

Title: Regulation of mechanical interactions between fibroblasts and the substratum by stretch-activated Ca2+ entry.

Journal: Journal of cell science 20040101

Title: Distribution of caveolin-1 in bovine lens and redistribution in cultured bovine lens epithelial cells upon confluence.

Journal: Experimental eye research 20040101

Title: Green tea polyphenol epigallocatechin-3-gallate inhibits platelet-derived growth factor-induced proliferation of human hepatic stellate cell line LI90.

Journal: Journal of hepatology 20040101

Title: Graphical representation and multicomponent analysis of single-frequency fluorescence lifetime imaging microscopy data.

Journal: Journal of microscopy 20040101

Title: Trafficking the NGF signal: implications for normal and degenerating neurons.

Journal: Progress in brain research 20040101

Title: Dd-STATb, a Dictyostelium STAT protein with a highly aberrant SH2 domain, functions as a regulator of gene expression during growth and early development.

Journal: Development (Cambridge, England) 20040101

Title: Coexistence of phosphotyrosine-dependent and -independent interactions between Cbl and Bcr-Abl.

Journal: Experimental hematology 20040101

Title: Cloning of a novel signaling molecule, AMSH-2, that potentiates transforming growth factor beta signaling.

Journal: BMC cell biology 20040101

Title: Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth.

Journal: Cancer research 20040101

Title: Insulin receptor activation and down-regulation by cationic lipid transfection reagents.

Journal: BMC cell biology 20040101

Title: Interaction of estrogen receptor alpha with protein kinase C alpha and c-Src in osteoblasts during differentiation.

Journal: Bone 20040101

Title: The protein tyrosine phosphatase CD45 is required for interleukin 6 signaling in U266 myeloma cells.

Journal: International journal of hematology 20040101

Title: Motility response to insulin-like growth factor-I (IGF-I) in MCF-7 cells is associated with IRS-2 activation and integrin expression.

Journal: Breast cancer research and treatment 20040101

Title: A flow cytometric assay for global estimation of tyrosine phosphorylation associated with capacitation of spermatozoa from two marsupial species, the tammar wallaby (Macropus eugenii) and the brushtail possum (Trichosurus vulpecula).

Journal: Reproduction (Cambridge, England) 20040101

Title: Acid phosphatase activities during the germination of Glycine max seeds.

Journal: Plant physiology and biochemistry : PPB 20040101

Title: Essential function for ErbB3 in breast cancer proliferation.

Journal: Breast cancer research : BCR 20040101

Title: Altered signalling thresholds in T lymphocytes cause autoimmune arthritis.

Journal: Arthritis research & therapy 20040101

Title: PI3 kinase is important for Ras, MEK and Erk activation of Epo-stimulated human erythroid progenitors.

Journal: BMC biology 20040101

Title: A cell-permeable phospholipase Cgamma1-binding peptide transduces neurons and impairs long-term spatial memory.

Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20040101

Title: Expression and functional effects of Eph receptor tyrosine kinase A family members on Langerhans like dendritic cells.

Journal: BMC immunology 20040101

Title: Proteomic method for identification of tyrosine-nitrated proteins.

Journal: Methods in molecular biology (Clifton, N.J.) 20040101

Title: Predicting N-terminal myristoylation sites in plant proteins.

Journal: BMC genomics 20040101

Title: Regulation of ErbB4 phosphorylation and cleavage by a novel histidine acid phosphatase.

Journal: Neuroscience 20040101

Title: The active metabolite of leflunomide, A771726, inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage.

Journal: Journal of bone and mineral metabolism 20040101

Title: Signaling by STATs.

Journal: Arthritis research & therapy 20040101

Title: Regulation of restitution after superficial injury in isolated guinea pig gastric mucosa.

Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20040101

Title: Formin homology 2 domains occur in multiple contexts in angiosperms.

Journal: BMC genomics 20040101

Title: Comprehensive de novo structure prediction in a systems-biology context for the archaea Halobacterium sp. NRC-1.

Journal: Genome biology 20040101

Title: Investigation of three new mouse mammary tumor cell lines as models for transforming growth factor (TGF)-beta and Neu pathway signaling studies: identification of a novel model for TGF-beta-induced epithelial-to-mesenchymal transition.

Journal: Breast cancer research : BCR 20040101

Title: Phosphorylated guanine nucleotide exchange factor C3G, induced by pervanadate and Src family kinases localizes to the Golgi and subcortical actin cytoskeleton.

Journal: BMC cell biology 20040101

Title: New approach for analysis of the phosphotyrosine proteome and its application to the chicken B cell line, DT40.

Journal: Journal of proteome research 20040101

Title: Reconstruction of ancestral protein sequences and its applications.

Journal: BMC evolutionary biology 20040101

Title: Modulation of Rho GTPases by type III secretion system translocated effectors of Yersinia.

Journal: Reviews of physiology, biochemistry and pharmacology 20040101

Title: Profiling of generic anti-phosphopeptide antibodies and kinases with peptide microarrays using radioactive and fluorescence-based assays.

Journal: Molecular diversity 20040101

Title: Characterization of dual specificity protein kinase from maize seedlings.

Journal: Acta biochimica Polonica 20040101

Title: Modeling of cell signaling pathways in macrophages by semantic networks.

Journal: BMC bioinformatics 20040101

Title: Comparisons of the M1 genome segments and encoded mu2 proteins of different reovirus isolates.

Journal: Virology journal 20040101

Title: Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation.

Journal: BMC biology 20040101

Title: Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction.

Journal: Reproductive biology and endocrinology : RB&E 20040101

Title: The docking protein Gab1 is the primary mediator of EGF-stimulated activation of the PI-3K/Akt cell survival pathway.

Journal: BMC biology 20040101

Title: Protein phosphatase-2A maintains focal adhesion complexes in keratinocytes and the loss of this regulation in squamous cell carcinomas.

Journal: Clinical & experimental metastasis 20040101

Title: Regulation of acetylcholine-induced phosphorylation of PLD1 in porcine tracheal smooth muscle.

Journal: Journal of biomedical science 20040101

Title: Phospholipids reduce gastric cancer cell adhesion to extracellular matrix in vitro.

Journal: BMC gastroenterology 20040101

Title: Ischemia induced focal adhesion kinase cleavage in rat lung.

Journal: Proceedings of the Western Pharmacology Society 20040101

Title: Nonspecific association of 2',3'-cyclic nucleotide 3'-phosphodiesterase with the rat forebrain postsynaptic density fraction.

Journal: Experimental & molecular medicine 20031231

Title: Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of B and T lymphocyte attenuator required for association with protein tyrosine phosphatases SHP-1 and SHP-2.

Journal: Biochemical and biophysical research communications 20031226

Title: Tyrosine phosphorylation of the Rab24 GTPase in cultured mammalian cells.

Journal: Biochemical and biophysical research communications 20031219

Title: LMW-PTP associates and dephosphorylates STAT5 interacting with its C-terminal domain.

Journal: Biochemical and biophysical research communications 20031212

Title: Hepatocyte growth factor activates several transduction pathways in rat pancreatic acini.

Journal: Biochimica et biophysica acta 20031207

Title: Tyrosine phosphorylation of HSP-90 during mammalian sperm capacitation.

Journal: Biology of reproduction 20031201

Title: Effect of hyperglycemia on signal transduction in skeletal muscle from diabetic Goto-Kakizaki rats.

Journal: Endocrinology 20031201

Title: Phosphatases in concert with kinases set the gain for signal transduction through the T cell receptor.

Journal: Molecular immunology 20031201

Title: PTTH-stimulated ecdysone secretion is dependent upon tyrosine phosphorylation in the prothoracic glands of Manduca sexta.

Journal: Insect biochemistry and molecular biology 20031201

Title: Cholecystokinin rapidly stimulates CrkII function in vivo in rat pancreatic acini. Formation of CrkII-protein complexes.

Journal: European journal of biochemistry 20031201

Title: Fc epsilon RI signaling of mast cells activates intracellular production of hydrogen peroxide: role in the regulation of calcium signals.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20031201

Title: Alternagin-C, a nonRGD-disintegrin, induces neutrophil migration via integrin signaling.

Journal: European journal of biochemistry 20031201

Title: Angiotensin II mediates Tyr-dephosphorylation in rat fetal kidney membranes.

Journal: Molecular and cellular biochemistry 20031201

Title: A novel competitive ELISA for both free and protein-bound nitrotyrosine.

Journal: Hybridoma and hybridomics 20031201

Title: Down-regulation of platelet-derived growth factor receptor signaling during myogenesis.

Journal: Cellular and molecular life sciences : CMLS 20031201

Title: Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.

Journal: Molecular cell 20031201

Title: The cholecystokinin system in the rat retina: receptor expression and in vivo activation of tyrosine phosphorylation pathways.

Journal: Neuropeptides 20031201

Title: Src-dependent phosphorylation of the EGF receptor Tyr-845 mediates Stat-p21waf1 pathway in A431 cells.

Journal: Genes to cells : devoted to molecular & cellular mechanisms 20031201

Title: Identification of PSD-93 as a substrate for the Src family tyrosine kinase Fyn.

Journal: The Journal of biological chemistry 20031128

Title: Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.

Journal: Journal of medicinal chemistry 20031120

Title: High-resolution structure of the Yersinia pestis protein tyrosine phosphatase YopH in complex with a phosphotyrosyl mimetic-containing hexapeptide.

Journal: Biochemistry 20031118

Title: Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells.

Journal: Journal of cell science 20031115

Title: Uncoupling between immunological synapse formation and functional outcome in human gamma delta T lymphocytes.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20031115

Title: Xenopus autosomal recessive hypercholesterolemia protein couples lipoprotein receptors with the AP-2 complex in oocytes and embryos and is required for vitellogenesis.

Journal: The Journal of biological chemistry 20031107

Title: Phosphoprotein phosphatase of Mycobacterium tuberculosis dephosphorylates serine-threonine kinases PknA and PknB.

Journal: Biochemical and biophysical research communications 20031107

Title: Attenuated signaling by a phosphotyrosine-null Epo receptor form in primary erythroid progenitor cells.

Journal: Blood 20031101

Title: Src mediates prolactin-dependent proliferation of T47D and MCF7 cells via the activation of focal adhesion kinase/Erk1/2 and phosphatidylinositol 3-kinase pathways.

Journal: Molecular endocrinology (Baltimore, Md.) 20031101

Title: Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor.

Journal: Molecular endocrinology (Baltimore, Md.) 20031101

Title: Janus kinase 2 determinants for growth hormone receptor association, surface assembly, and signaling.

Journal: Molecular endocrinology (Baltimore, Md.) 20031101

Title: Proteomic approaches to the analysis of early events in colony-stimulating factor-1 signal transduction.

Journal: Molecular & cellular proteomics : MCP 20031101

Title: Transactivation of epidermal growth factor receptor after heparin-binding epidermal growth factor-like growth factor shedding in the migration of prostate cancer cells promoted by bombesin.

Journal: The Prostate 20031101

Title: Oxygen radical production in neutrophils interacting with platelets and surface-immobilized plasma proteins: role of tyrosine phosphorylation.

Journal: Journal of biomedical materials research. Part A 20031101

Title: Apoptosis of lymphocytes induced by chromium(VI/V) is through ROS-mediated activation of Src-family kinases and caspase-3.

Journal: Free radical biology & medicine 20031101

Title: Tyrosine 116 of the herpes simplex virus type 1 IEalpha22 protein is an ocular virulence determinant and potential phosphorylation site.

Journal: Investigative ophthalmology & visual science 20031101

Title: Potent and selective inhibitors of the Met [hepatocyte growth factor/scatter factor (HGF/SF) receptor] tyrosine kinase block HGF/SF-induced tumor cell growth and invasion.

Journal: Molecular cancer therapeutics 20031101

Title: Involvement of oligosaccharide changes in alpha5beta1 integrin in a cisplatin-resistant human squamous cell carcinoma cell line.

Journal: Molecular cancer therapeutics 20031101

Title: Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development.

Journal: PLoS biology 20031101

Title: T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression.

Journal: PLoS biology 20031101

Title: Differences and similarities in tyrosine phosphorylation of proteins in platelets from human and pig species.

Journal: Journal of thrombosis and haemostasis : JTH 20031101

Title: Combinatorial chemistry.

Journal: Drug discovery today 20031101

Title: Amyloid beta peptide specifically promotes phosphorylation and nuclear translocation of the extracellular signal-regulated kinase in cultured rat cortical astrocytes.

Journal: Journal of pharmacological sciences 20031101

Title: The antidiabetic agent sodium tungstate activates glycogen synthesis through an insulin receptor-independent pathway.

Journal: The Journal of biological chemistry 20031031

Title: Hypoxia activates signal transducers and activators of transcription 5 (STAT5) and increases its binding activity to the GAS element in mammary epithelial cells.

Journal: Experimental & molecular medicine 20031031

Title: FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies.

Journal: Neuron 20031030

Title: [p120(ctn) tyrosine phosphorylation are involved in the biologic behavior changes of hepatocellular carcinoma cells].

Journal: Zhonghua yi xue za zhi 20031025

Title: An SH2 domain-dependent, phosphotyrosine-independent interaction between Vav1 and the Mer receptor tyrosine kinase: a mechanism for localizing guanine nucleotide-exchange factor action.

Journal: The Journal of biological chemistry 20031024

Title: Design and synthesis of small chemical inhibitors containing different scaffolds for lck SH2 domain.

Journal: Bioorganic & medicinal chemistry letters 20031020

Title: Nuclear shift of hnRNP K protein in neoplasms and other states of enhanced cell proliferation.

Journal: British journal of cancer 20031020

Title: Roles for an Epo receptor Tyr-343 Stat5 pathway in proliferative co-signaling with kit.

Journal: The Journal of biological chemistry 20031017

Title: The UIM domain of Hrs couples receptor sorting to vesicle formation.

Journal: Journal of cell science 20031015

Title: A cleanup step maximizes the immunoprecipitation of tyrosine-phosphorylated peptides by a conventional antiphosphotyrosine antibody.

Journal: Analytical biochemistry 20031015

Title: Reactive oxygen species promote tyrosine phosphorylation and capacitation in equine spermatozoa.

Journal: Theriogenology 20031015

Title: The hemopoietic Rho/Rac guanine nucleotide exchange factor Vav1 regulates N-formyl-methionyl-leucyl-phenylalanine-activated neutrophil functions.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20031015

Title: Antitumor effects of epidermal growth factor receptor antisense oligonucleotides in combination with docetaxel in squamous cell carcinoma of the head and neck.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20031015

Title: The phosphotyrosine phosphatase SHP2 is a critical mediator of transformation induced by the oncogenic fibroblast growth factor receptor 3.

Journal: Oncogene 20031009

Title: FGFR3IIIS: a novel soluble FGFR3 spliced variant that modulates growth is frequently expressed in tumour cells.

Journal: British journal of cancer 20031006

Title: Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1.

Journal: The Journal of biological chemistry 20031003

Title: Effects of deficiencies of STAMs and Hrs, mammalian class E Vps proteins, on receptor downregulation.

Journal: Biochemical and biophysical research communications 20031003

Title: Grb2 regulation of the actin-based cytoskeleton is required for ligand-independent EGF receptor-mediated oncogenesis.

Journal: Oncogene 20031002

Title: Characterization of insulin signaling in rat retina in vivo and ex vivo.

Journal: American journal of physiology. Endocrinology and metabolism 20031001

Title: Recruitment of endothelial caveolae into mechanotransduction pathways by flow conditioning in vitro.

Journal: American journal of physiology. Heart and circulatory physiology 20031001

Title: STAT1 plays an essential role in LPS/D-galactosamine-induced liver apoptosis and injury.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20031001

Title: Aging-related attenuation of EGF receptor signaling is mediated in part by increased protein tyrosine phosphatase activity.

Journal: Experimental cell research 20031001

Title: Keap1 in adhesion complexes.

Journal: Cell motility and the cytoskeleton 20031001

Title: Basic fibroblast and epidermal growth factors stimulate survival in adult porcine photoreceptor cell cultures.

Journal: Investigative ophthalmology & visual science 20031001

Title: Rapid and sensitive identification of epitope-containing peptides by direct matrix-assisted laser desorption/ionization tandem mass spectrometry of peptides affinity-bound to antibody beads.

Journal: Journal of the American Society for Mass Spectrometry 20031001

Title: Light regulation of the insulin receptor in the retina.

Journal: Molecular neurobiology 20031001

Title: Aged mice exhibit distinct B cell precursor phenotypes differing in activation, proliferation and apoptosis.

Journal: Experimental gerontology 20031001

Title: Relationship between phosphatase activity and cytotoxic effect of two protein phosphatase inhibitors, okadaic acid and pervanadate, on human myeloid leukemia cell line.

Journal: Journal of enzyme inhibition and medicinal chemistry 20031001

Title: Plasma membrane phospholipid scramblase 1 promotes EGF-dependent activation of c-Src through the epidermal growth factor receptor.

Journal: The Journal of biological chemistry 20030926

Title: Fragment screening and assembly: a highly efficient approach to a selective and cell active protein tyrosine phosphatase 1B inhibitor.

Journal: Journal of medicinal chemistry 20030925

Title: Lymphocyte function-associated antigen-1-mediated T cell adhesion is impaired by low molecular weight phosphotyrosine phosphatase-dependent inhibition of FAK activity.

Journal: The Journal of biological chemistry 20030919

Title: Her-2/neu-triggered intracellular tyrosine kinase activation: in vivo relevance of ligand-independent activation mechanisms and impact upon the efficacy of trastuzumab-based treatment.

Journal: British journal of cancer 20030915

Title: Transmembrane modulator-dependent bacterial tyrosine kinase activates UDP-glucose dehydrogenases.

Journal: The EMBO journal 20030915

Title: p130Cas Couples the tyrosine kinase Bmx/Etk with regulation of the actin cytoskeleton and cell migration.

Journal: The Journal of biological chemistry 20030912

Title: Integrin alpha 4 beta 1-dependent T cell migration requires both phosphorylation and dephosphorylation of the alpha 4 cytoplasmic domain to regulate the reversible binding of paxillin.

Journal: The Journal of biological chemistry 20030912

Title: Cholecystokinin-stimulated protein kinase C-delta kinase activation, tyrosine phosphorylation, and translocation are mediated by Src tyrosine kinases in pancreatic acinar cells.

Journal: The Journal of biological chemistry 20030912

Title: PAR-2 modulates pepsinogen secretion from gastric-isolated chief cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030901

Title: dDYRK2: a novel dual-specificity tyrosine-phosphorylation-regulated kinase in Drosophila.

Journal: The Biochemical journal 20030901

Title: Low molecular weight phosphotyrosine protein phosphatase from PC12 cells. Purification, some properties and expression during neurogenesis in vitro and in vivo.

Journal: The international journal of biochemistry & cell biology 20030901

Title: Cholesterol dependence of vascular ERK1/2 activation and growth in response to stretch: role of endothelin-1.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20030901

Title: Tyrosine kinase mediated phosphorylation of the hexamerin receptor in the rice moth Corcyra cephalonica by ecdysteroids.

Journal: Insect biochemistry and molecular biology 20030901

Title: Vascular endothelial growth factor expression and signaling in the lens.

Journal: Investigative ophthalmology & visual science 20030901

Title: Helicobacter pylori CagA as a potential bacterial oncoprotein in gastric carcinogenesis.

Journal: Pathologie-biologie 20030901

Title: Studies of ligand-induced site-specific phosphorylation of epidermal growth factor receptor.

Journal: Journal of the American Society for Mass Spectrometry 20030901

Title: Identification and functional assessment of novel and known insulin receptor mutations in five patients with syndromes of severe insulin resistance.

Journal: The Journal of clinical endocrinology and metabolism 20030901

Title: Mouse lipocalin as an enhancer of spermatozoa motility.

Journal: Molecular biology reports 20030901

Title: Redox regulation of protein tyrosine phosphatases during receptor tyrosine kinase signal transduction.

Journal: Trends in biochemical sciences 20030901

Title: Inhibition of interferon gamma signaling by the short chain fatty acid butyrate.

Journal: Molecular cancer research : MCR 20030901

Title: Ionizing radiation modules of the expression and tyrosine phosphorylation of the focal adhesion-associated proteins focal adhesion kinase (FAK) and its substrates p130cas and paxillin in A549 human lung carcinoma cells in vitro.

Journal: International journal of radiation biology 20030901

Title: 2', 3'-cyclic nucleotide 3'-phosphodiesterase is expressed in dissociated rat cerebellar cells and included in the postsynaptic density fraction.

Journal: Molecules and cells 20030831

Title: Flagellar adhesion between mating type plus and mating type minus gametes activates a flagellar protein-tyrosine kinase during fertilization in Chlamydomonas.

Journal: The Journal of biological chemistry 20030829

Title: Sensitivity of rabbit aorta and mesenteric artery to norepinephrine: role of tyrosine kinases.

Journal: European journal of pharmacology 20030829

Title: Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck.

Journal: The Journal of biological chemistry 20030822

Title: Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling.

Journal: The Journal of biological chemistry 20030822

Title: Concise and enantioselective synthesis of Fmoc-Pmp(But)2-OH and design of potent Pmp-containing Grb2-SH2 domain antagonists.

Journal: Organic letters 20030821

Title: The noncatalytic domains of Lck regulate its dephosphorylation by CD45.

Journal: Biochimica et biophysica acta 20030821

Title: Feedback regulation of MAPK signalling by an RNA-binding protein.

Journal: Nature 20030821

Title: 4-Hydroxycoumarin disorganizes the actin cytoskeleton in B16-F10 melanoma cells but not in B82 fibroblasts, decreasing their adhesion to extracellular matrix proteins and motility.

Journal: Cancer letters 20030820

Title: Selective inhibition of T cell activation via CD147 through novel modulation of lipid rafts.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030815

Title: Intracellular domain of brain endothelial intercellular adhesion molecule-1 is essential for T lymphocyte-mediated signaling and migration.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030815

Title: Grb2-independent recruitment of Gab1 requires the C-terminal lobe and structural integrity of the Met receptor kinase domain.

Journal: The Journal of biological chemistry 20030808

Title: Structural basis for a non-phosphorus-containing cyclic peptide binding to Grb2-SH2 domain with high affinity.

Journal: Biochemical and biophysical research communications 20030808

Title: Nitric oxide-induced inhibition of aortic smooth muscle cell motility: role of PTP-PEST and adaptor proteins p130cas and Crk.

Journal: American journal of physiology. Heart and circulatory physiology 20030801

Title: Focal adhesion kinase is required for endothelin-induced cell cycle progression of cultured astrocytes.

Journal: Glia 20030801

Title: Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation.

Journal: Traffic (Copenhagen, Denmark) 20030801

Title: Functional characterization of W147A: a high-affinity interleukin-11 antagonist.

Journal: Endocrinology 20030801

Title: Protein tyrosine phosphatase 1B inhibition: opportunities and challenges.

Journal: Current medicinal chemistry 20030801

Title: Differential analysis of phosphorylated proteins in resting and thrombin-stimulated human platelets.

Journal: Analytical and bioanalytical chemistry 20030801

Title: Coupling of folding and binding in the PTB domain of the signaling protein Shc.

Journal: Structure (London, England : 1993) 20030801

Title: Parathyroid hormone-related peptide modulates signal pathways in skin and hair follicle cells.

Journal: Experimental dermatology 20030801

Title: Tyrosine phosphate in melanoma progression.

Journal: The British journal of dermatology 20030801

Title: Staining proteins in gels.

Journal: Current protocols in molecular biology 20030801

Title: Selective protein tyrosine phosphatase 1B inhibitors: targeting the second phosphotyrosine binding site with non-carboxylic acid-containing ligands.

Journal: Journal of medicinal chemistry 20030731

Title: Cell shape provides global control of focal adhesion assembly.

Journal: Biochemical and biophysical research communications 20030725

Title: Relevance of Akt phosphorylation in cell transformation induced by Jaagsiekte sheep retrovirus.

Journal: Virology 20030720

Title: Evolution of key cell signaling and adhesion protein families predates animal origins.

Journal: Science (New York, N.Y.) 20030718

Title: PTPRQ is a novel phosphatidylinositol phosphatase that can be expressed as a cytoplasmic protein or as a subcellularly localized receptor-like protein.

Journal: Experimental cell research 20030715

Title: SH2 and PTB domains in tyrosine kinase signaling.

Journal: Science's STKE : signal transduction knowledge environment 20030715

Title: Identification and characterization of signal transducer and activator of transcription 3 recruitment sites within the epidermal growth factor receptor.

Journal: Cancer research 20030715

Title: Changes in L1 and NCAM expression in the rat suprachiasmatic nucleus during growth and after orbital enucleation.

Journal: Brain research. Developmental brain research 20030712

Title: The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region.

Journal: Biochemistry 20030708

Title: Engineering a 'methionine clamp' into Src family kinases enhances specificity toward unnatural ATP analogues.

Journal: Biochemistry 20030708

Title: Potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics.

Journal: Bioorganic & medicinal chemistry letters 20030707

Title: Directed evolution of a yeast arsenate reductase into a protein-tyrosine phosphatase.

Journal: The Journal of biological chemistry 20030704

Title: A differential mechanism is involved during heparin- and cryopreservation-induced capacitation of bovine spermatozoa.

Journal: Biology of reproduction 20030701

Title: Protein tyrosine phosphatase activity regulates endothelial cell-cell interactions, the paracellular pathway, and capillary tube stability.

Journal: American journal of physiology. Lung cellular and molecular physiology 20030701

Title: Correlation of P-cadherin and beta-catenin expression and phosphorylation with carcinogenesis in rat tongue cancer induced with 4-nitroquinoline 1-oxide.

Journal: Oral oncology 20030701

Title: Novel stimulatory actions of the phytoestrogen genistein: effects on the gain of cardiac excitation-contraction coupling.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030701

Title: EGF receptor-mediated, c-Src-dependent, activation of Stat5b is downregulated in mitogenically responsive hepatocytes.

Journal: Journal of cellular physiology 20030701

Title: Differential regulation of junctional complex assembly in renal epithelial cell lines.

Journal: American journal of physiology. Cell physiology 20030701

Title: An ecto-protein tyrosine phosphatase of Entamoeba histolytica induces cellular detachment by disruption of actin filaments in HeLa cells.

Journal: International journal for parasitology 20030701

Title: Copper-homocysteine complexes and potential physiological actions.

Journal: Journal of inorganic biochemistry 20030701

Title: Effect of phosphotyrosine proteins on phorbol myristate acetate-induced NADPH oxidase activation in guinea pig peritoneal polymorphonuclear leukocytes.

Journal: Biological & pharmaceutical bulletin 20030701

Title: Interleukin-10 activation of the interleukin-10E1 pathway and tissue inhibitor of metalloproteinase-1 expression is enhanced by proteasome inhibitors in primary prostate tumor lines.

Journal: Molecular cancer research : MCR 20030701

Title: Platelet proteomics.

Journal: Journal of thrombosis and haemostasis : JTH 20030701

Title: A conformational switch controls the DNA cleavage activity of lambda integrase.

Journal: Molecular cell 20030701

Title: Protein phosphorylation during the process of interaction of Toxoplasma gondii with host cells.

Journal: Journal of submicroscopic cytology and pathology 20030701

Title: Utilization of a beta-aminophosphotyrosyl mimetic in the design and synthesis of macrocyclic Grb2 SH2 domain-binding peptides.

Journal: Journal of medicinal chemistry 20030619

Title: Design and synthesis of phosphotyrosine mimetics.

Journal: Bioorganic & medicinal chemistry letters 20030616

Title: Alternative splicing variants of dual specificity tyrosine phosphorylated and regulated kinase 1B exhibit distinct patterns of expression and functional properties.

Journal: The Biochemical journal 20030615

Title: Polyvalent antigens stabilize B cell antigen receptor surface signaling microdomains.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030615

Title: c-Cbl is a critical modulator of the Ron tyrosine kinase receptor.

Journal: Oncogene 20030612

Title: IL-10 signaling via IL-10E1 is dependent on tyrosine phosphorylation in the IL-10R alpha chain in human primary prostate cancer cell lines.

Journal: Oncogene 20030612

Title: Dynamics and DNA substrate recognition by the catalytic domain of lambda integrase.

Journal: Journal of molecular biology 20030606

Title: Interleukin-4 and interleukin-13 signaling connections maps.

Journal: Science (New York, N.Y.) 20030606

Title: Potent, selective inhibitors of protein tyrosine phosphatase 1B.

Journal: Bioorganic & medicinal chemistry letters 20030602

Title: A cholesterol-regulated PP2A/HePTP complex with dual specificity ERK1/2 phosphatase activity.

Journal: The EMBO journal 20030602

Title: Post-mortem interval effects on the phosphorylation of signaling proteins.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030601

Title: Commentary: effect of flavonoids on normal and leukemic cells.

Journal: Leukemia research 20030601

Title: Cyclic phosphatidic acid inhibits RhoA-mediated autophosphorylation of FAK at Tyr-397 and subsequent tumor-cell invasion.

Journal: International journal of oncology 20030601

Title: IL-21 in synergy with IL-15 or IL-18 enhances IFN-gamma production in human NK and T cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030601

Title: Thiol-modifying phenylarsine oxide inhibits guanine nucleotide binding of Rho but not of Rac GTPases.

Journal: Molecular pharmacology 20030601

Title: Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes.

Journal: Diabetes 20030601

Title: Insulin receptor substrate-4 signaling in quiescent rat hepatocytes and in regenerating rat liver.

Journal: Hepatology (Baltimore, Md.) 20030601

Title: The FRK/RAK-SHB signaling cascade: a versatile signal-transduction pathway that regulates cell survival, differentiation and proliferation.

Journal: Current molecular medicine 20030601

Title: Fragmentation of cationized phosphotyrosine containing peptides by atmospheric pressure MALDI/Ion trap mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry 20030601

Title: Phosphotyrosyl mimetics in the development of signal transduction inhibitors.

Journal: Accounts of chemical research 20030601

Title: Analysis of protein tyrosine phosphorylation by nanoelectrospray ionization high-resolution tandem mass spectrometry and tyrosine-targeted product ion scanning.

Journal: Analytical chemistry 20030601

Title: The EphA8 receptor phosphorylates and activates low molecular weight phosphotyrosine protein phosphatase in vitro.

Journal: Journal of biochemistry and molecular biology 20030531

Title: Receptor tyrosine kinase Axl modulates the osteogenic differentiation of pericytes.

Journal: Circulation research 20030530

Title: Naringenin inhibits phosphoinositide 3-kinase activity and glucose uptake in 3T3-L1 adipocytes.

Journal: Biochemical and biophysical research communications 20030530

Title: Thymidine phosphorylase and 2-deoxyribose stimulate human endothelial cell migration by specific activation of the integrins alpha 5 beta 1 and alpha V beta 3.

Journal: The Journal of biological chemistry 20030523

Title: Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells. Modulation of EGF-induced trafficking and signaling.

Journal: The Journal of biological chemistry 20030523

Title: Matrix-independent activation of phosphatidylinositol 3-kinase, Stat3, and cyclin A-associated Cdk2 Is essential for anchorage-independent growth of v-Ros-transformed chicken embryo fibroblasts.

Journal: The Journal of biological chemistry 20030523

Title: Phosphospecific site tyrosine phosphorylation of p125FAK and proline-rich kinase 2 is differentially regulated by cholecystokinin receptor type A activation in pancreatic acini.

Journal: The Journal of biological chemistry 20030523

Title: Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B.

Journal: Journal of medicinal chemistry 20030522

Title: Filopodial calcium transients regulate growth cone motility and guidance through local activation of calpain.

Journal: Neuron 20030522

Title: L-type voltage-gated calcium channel attends regulation of tyrosine phosphorylation of NMDA receptor subunit 2A induced by transient brain ischemia.

Journal: Brain research 20030516

Title: Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase.

Journal: Oncogene 20030515

Title: Focal adhesions and associated proteins in medullary thyroid carcinoma cells.

Journal: The Journal of surgical research 20030515

Title: Smooth muscle cell migration stimulated by interleukin 6 is associated with cytoskeletal reorganization.

Journal: The Journal of surgical research 20030515

Title: Discovery of a new phosphotyrosine mimetic for PTP1B using breakaway tethering.

Journal: Journal of the American Chemical Society 20030514

Title: Molecular dynamics, free energy, and SPR analyses of the interactions between the SH2 domain of Grb2 and ErbB phosphotyrosyl peptides.

Journal: Biochemistry 20030513

Title: Analysis of the leukemia inhibitory factor receptor functional domains by chimeric receptors and cytokines.

Journal: Biochemistry 20030513

Title: Chemical dissection of the effects of tyrosine phosphorylation of SHP-2.

Journal: Biochemistry 20030513

Title: Peptidyl aldehydes as reversible covalent inhibitors of SRC homology 2 domains.

Journal: Biochemistry 20030506

Title: Characterization of phosphopeptide motifs specific for the Src homology 2 domains of signal transducer and activator of transcription 1 (STAT1) and STAT3.

Journal: The Journal of biological chemistry 20030502

Title: Phosphoinositide 3-kinase-mediated reduction of insulin receptor substrate-1/2 protein expression via different mechanisms contributes to the insulin-induced desensitization of its signaling pathways in L6 muscle cells.

Journal: The Journal of biological chemistry 20030502

Title: The mRNA transcription/processing factor Ssu72 is a potential tyrosine phosphatase.

Journal: The Journal of biological chemistry 20030502

Title: Structural and thermodynamic basis for the interaction of the Src SH2 domain with the activated form of the PDGF beta-receptor.

Journal: Journal of molecular biology 20030502

Title: Radiation stimulates HGF receptor/c-Met expression that leads to amplifying cellular response to HGF stimulation via upregulated receptor tyrosine phosphorylation and MAP kinase activity in pancreatic cancer cells.

Journal: International journal of cancer 20030501

Title: Platelet derived growth factor (PDGF) responsive epidermis formed from human keratinocytes transduced with the PDGF beta receptor gene.

Journal: The Journal of investigative dermatology 20030501

Title: Effect of in vivo administered hexachlorobenzene on epidermal growth factor receptor levels, protein tyrosine kinase activity, and phosphotyrosine content in rat liver.

Journal: Biochemical pharmacology 20030501

Title: Examining both sides of a Janus PTB domain.

Journal: Structure (London, England : 1993) 20030501

Title: Increased ubiquitination and reduced expression of LCK in T lymphocytes from patients with systemic lupus erythematosus.

Journal: Arthritis and rheumatism 20030501

Title: SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer.

Journal: Molecular cancer therapeutics 20030501

Title: Selective adhesion of osteoblastic cells to different integrin ligands induces osteopontin gene expression.

Journal: Matrix biology : journal of the International Society for Matrix Biology 20030501

Title: Fibroblast growth factor-2-induced signaling through lipid raft-associated fibroblast growth factor receptor substrate 2 (FRS2).

Journal: The Journal of biological chemistry 20030418

Title: Development of an efficient 'substrate-trapping' mutant of Src homology phosphotyrosine phosphatase 2 and identification of the epidermal growth factor receptor, Gab1, and three other proteins as target substrates.

Journal: The Journal of biological chemistry 20030418

Title: RhoA and ROCK promote migration by limiting membrane protrusions.

Journal: The Journal of biological chemistry 20030411

Title: Ethanol feeding induces insulin resistance with enhanced PI 3-kinase activation.

Journal: Biochemical and biophysical research communications 20030411

Title: An experimental and theoretical study of the 13C and 31P chemical shielding tensors in solid O-phosphorylated amino acids.

Journal: Journal of the American Chemical Society 20030409

Title: Activation of phospholipase D is not mediated by direct phosphorylation on tyrosine residues.

Journal: Biochimica et biophysica acta 20030408

Title: Redox modulation of protein kinase/phosphatase balance in melanoma cells: the role of endogenous and gamma-glutamyltransferase-dependent H2O2 production.

Journal: Biochimica et biophysica acta 20030407

Title: The antiinflammatory endothelial tyrosine kinase Tie2 interacts with a novel nuclear factor-kappaB inhibitor ABIN-2.

Journal: Circulation research 20030404

Title: TMC-264, a novel antiallergic heptaketide produced by the fungus Phoma sp. TC 1674.

Journal: Organic letters 20030403

Title: Genetic identification of effectors downstream of Neu (ErbB-2) autophosphorylation sites in a Drosophila model.

Journal: Oncogene 20030403

Title: Positive and negative regulation of T-cell activation through kinases and phosphatases.

Journal: The Biochemical journal 20030401

Title: Development of the signalling pathways associated with sperm capacitation during epididymal maturation.

Journal: Molecular reproduction and development 20030401

Title: Localization of tyrosine phosphorylated proteins in human sperm and relation to capacitation and zona pellucida binding.

Journal: Biology of reproduction 20030401

Title: Molecular mechanisms of autosomal recessive hypercholesterolemia.

Journal: Current opinion in lipidology 20030401

Title: Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance.

Journal: Diabetes 20030401

Title: Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 activity exerts an antidiabetic action in Goto-Kakizaki rats.

Journal: Diabetes 20030401

Title: Sensitivity to imatinib but low frequency of the TEL/PDGFRbeta fusion protein in chronic myelomonocytic leukemia.

Journal: Haematologica 20030401

Title: A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030401

Title: Constitutive activation of Jak2 contributes to proliferation and resistance to apoptosis in NPM/ALK-transformed cells.

Journal: Experimental hematology 20030401

Title: Nitric oxide-induced epidermal growth factor-dependent phosphorylations in A431 tumour cells.

Journal: European journal of biochemistry 20030401

Title: Hyperoxia alters phorbol ester-induced phospholipase D activation in bovine lung microvascular endothelial cells.

Journal: Antioxidants & redox signaling 20030401

Title: Relationship between cardiac protein tyrosine phosphorylation and myofibrillogenesis during axolotl heart development.

Journal: Tissue & cell 20030401

Title: Profiling the global tyrosine phosphorylation state.

Journal: Molecular & cellular proteomics : MCP 20030401

Title: Incidence of sperm-tail tyrosine phosphorylation and hyperactivated motility in normozoospermic and asthenozoospermic human sperm samples.

Journal: Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al 20030401

Title: Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation.

Journal: The Journal of biological chemistry 20030328

Title: Tyrosine dephosphorylation and ethanol inhibition of N-Methyl-D-aspartate receptor function.

Journal: The Journal of biological chemistry 20030328

Title: Phosphatase activity characterization on the surface of intact bloodstream forms of Trypanosoma brucei.

Journal: FEMS microbiology letters 20030328

Title: Early intracellular events induced by in vivo leptin treatment in mouse skeletal muscle.

Journal: Molecular and cellular endocrinology 20030328

Title: Mechanism of inhibition of site-specific recombination by the Holliday junction-trapping peptide WKHYNY: insights into phage lambda integrase-mediated strand exchange.

Journal: Journal of molecular biology 20030321

Title: A myristoyl/phosphotyrosine switch regulates c-Abl.

Journal: Cell 20030321

Title: Structural basis for the autoinhibition of c-Abl tyrosine kinase.

Journal: Cell 20030321

Title: A constitutively active ErbB4 mutant inhibits drug-resistant colony formation by the DU-145 and PC-3 human prostate tumor cell lines.

Journal: Cancer letters 20030320

Title: Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption.

Journal: Journal of cell science 20030315

Title: MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models.

Journal: Blood 20030315

Title: Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030315

Title: Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice.

Journal: Cancer research 20030315

Title: The function of the protein tyrosine phosphatase SHP-1 in cancer.

Journal: Gene 20030313

Title: Structure-based design of thioether-bridged cyclic phosphopeptides binding to Grb2-SH2 domain.

Journal: Bioorganic & medicinal chemistry letters 20030310

Title: Loss of ligand-binding specificity of fibroblast growth factor receptor 2 by RNA splicing in human chondrosarcoma cells.

Journal: Cancer letters 20030310

Title: Cysteine residues in the C-terminal lobe of Src: their role in the suppression of the Src kinase.

Journal: Oncogene 20030306

Title: The Polycomb-group protein ENX-2 interacts with ZAP-70.

Journal: Immunology letters 20030303

Title: c-Abl is required for oxidative stress-induced phosphorylation of caveolin-1 on tyrosine 14.

Journal: Cellular signalling 20030301

Title: The adaptor function of SHP-2 downstream of the prolactin receptor is required for the recruitment of p29, a substrate of SHP-2.

Journal: Cellular signalling 20030301

Title: Interaction of the growth hormone receptor with cytokine-induced Src homology domain 2 protein in rat adipocytes.

Journal: Endocrinology 20030301

Title: WW domain sequence activity relationships identified using ligand recognition propensities of 42 WW domains.

Journal: Protein science : a publication of the Protein Society 20030301

Title: Soy-derived isoflavones exert opposing actions on Guinea pig ventricular myocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20030301

Title: Role of protein tyrosine phosphorylation in the thapsigargin-induced intracellular Ca(2+) store depletion during human sperm acrosome reaction.

Journal: Molecular human reproduction 20030301

Title: The extracellular portion of the insulin receptor beta-subunit regulates the cellular trafficking of the insulin-insulin receptor complex. Studies on Chinese hamster ovary cells carrying the Cys 860-->Ser insulin receptor mutation.

Journal: European journal of endocrinology 20030301

Title: Analysis of tyrosine phosphorylation in resident peritoneal cells during diet restriction by laser scanning cytometry.

Journal: Shock (Augusta, Ga.) 20030301

Title: Phosphotyrosine mapping in Bcr/Abl oncoprotein using phosphotyrosine-specific immonium ion scanning.

Journal: Molecular & cellular proteomics : MCP 20030301

Title: Detection of tyrosine phosphorylated peptides via skimmer collision-induced dissociation/ion trap mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20030301

Title: Evidence for a direct effect of captopril on early steps of insulin action in BC3H-1 myocytes.

Journal: Metabolism: clinical and experimental 20030301

Title: 1H, 15N and 13C resonance assignments for the PTB domain of the signaling protein Shc.

Journal: Journal of biomolecular NMR 20030301

Title: Membrane-bound acid phosphatase (MAP) from Entamoeba histolytica has phosphotyrosine phosphatase activity and disrupts the actin cytoskeleton of host cells.

Journal: Parasitology 20030301

Title: Diversity in the SH2 domain family phosphotyrosyl peptide binding site.

Journal: Protein engineering 20030301

Title: Involvement of the tyrosine phosphorylation on GSH transport in NIH3T3 fibroblasts.

Journal: IUBMB life 20030301

Title: Follicle-stimulating hormone activates extracellular signal-regulated kinase but not extracellular signal-regulated kinase kinase through a 100-kDa phosphotyrosine phosphatase.

Journal: The Journal of biological chemistry 20030227

Title: The pp60c-Src inhibitor PP1 is non-competitive against ATP.

Journal: FEBS letters 20030227

Title: Hepatocyte growth factor receptor tyrosine kinase met is a substrate of the receptor protein-tyrosine phosphatase DEP-1.

Journal: The Journal of biological chemistry 20030221

Title: Syk, a protein-tyrosine kinase, suppresses the cell motility and nuclear factor kappa B-mediated secretion of urokinase type plasminogen activator by inhibiting the phosphatidylinositol 3'-kinase activity in breast cancer cells.

Journal: The Journal of biological chemistry 20030221

Title: Crystal structure of human protein-tyrosine phosphatase SHP-1.

Journal: The Journal of biological chemistry 20030221

Title: The role of C-terminal tyrosine phosphorylation in the regulation of SHP-1 explored via expressed protein ligation.

Journal: The Journal of biological chemistry 20030214

Title: Structural plasticity of the Flp-Holliday junction complex.

Journal: Journal of molecular biology 20030214

Title: The Shb adaptor protein causes Src-dependent cell spreading and activation of focal adhesion kinase in murine brain endothelial cells.

Journal: Cellular signalling 20030201

Title: Angiotensin II effects on STAT3 phosphorylation in cardiomyocytes: evidence for Erk-dependent Tyr705 dephosphorylation.

Journal: Basic research in cardiology 20030201

Title: Purification and characterization of a protein tyrosine acid phosphatase from boar seminal vesicle glands.

Journal: Theriogenology 20030201

Title: Suppressive effect of endogenous regucalcin on protein tyrosine phosphatase activity in the nucleus of rat brain: attenuation with increasing age.

Journal: International journal of molecular medicine 20030201

Title: Low free energy cost of very long loop insertions in proteins.

Journal: Protein science : a publication of the Protein Society 20030201

Title: Prediction of secondary ionization of the phosphate group in phosphotyrosine peptides.

Journal: Biophysical journal 20030201

Title: Invasion of retinal pigment epithelial cells: N-cadherin, hepatocyte growth factor, and focal adhesion kinase.

Journal: Investigative ophthalmology & visual science 20030201

Title: Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030201

Title: Effect of exogenously administered HGF activator in liver regeneration.

Journal: Transplantation proceedings 20030201

Title: Involvement of linker for activation of T cells in the costimulatory signaling pathways.

Journal: Transplantation proceedings 20030201

Title: The HIV protease inhibitor indinavir impairs glycogen synthesis in HepG2 hepatoma cells.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20030201

Title: Kinetic and site-directed mutagenesis studies of prevotella intermedia acid phosphatase.

Journal: Protein and peptide letters 20030201

Title: JAK/STAT but not ERK1/ERK2 pathway mediates interleukin (IL)-6/soluble IL-6R down-regulation of Type II collagen, aggrecan core, and link protein transcription in articular chondrocytes. Association with a down-regulation of SOX9 expression.

Journal: The Journal of biological chemistry 20030131

Title: The requirement of specific membrane domains for Raf-1 phosphorylation and activation.

Journal: The Journal of biological chemistry 20030131

Title: Platelet-endothelial cell adhesion molecule-1 modulates endothelial migration through its immunoreceptor tyrosine-based inhibitory motif.

Journal: Biochemical and biophysical research communications 20030131

Title: Ezrin is a substrate for Lck in T cells.

Journal: FEBS letters 20030130

Title: Macrocyclization in the design of Grb2 SH2 domain-binding ligands exhibiting high potency in whole-cell systems.

Journal: Journal of medicinal chemistry 20030116

Title: A synthetic heparin-mimicking polyanionic compound inhibits central nervous system inflammation.

Journal: Journal of the neurological sciences 20030115

Title: Effect of a novel somatostatin analogue combined with cytotoxic drugs on human tumour xenografts and metastasis of B16 melanoma.

Journal: British journal of cancer 20030113

Title: Mutation of the protein tyrosine kinase consensus site in the herpes simplex virus 1 alpha22 gene alters ICP22 posttranslational modification.

Journal: Virology 20030105

Title: Stromal cell-derived factor-1alpha induces tube-like structure formation of endothelial cells through phosphoinositide 3-kinase.

Journal: The Journal of biological chemistry 20030103

Title: Protein kinase D mediates a stress-induced NF-kappaB activation and survival pathway.

Journal: The EMBO journal 20030102

Title: Protein-tyrosine-phosphatase 1B activation is regulated developmentally in muscle of neonatal pigs.

Journal: American journal of physiology. Endocrinology and metabolism 20030101

Title: Protein phosphatase-2A restricts migration of Lewis lung carcinoma cells by modulating the phosphorylation of focal adhesion proteins.

Journal: International journal of cancer 20030101

Title: Receptor protein tyrosine phosphatases as mediators of cellular adhesion.

Journal: Frontiers in bioscience : a journal and virtual library 20030101

Title: Porcine sperm capacitation and tyrosine kinase activity are dependent on bicarbonate and calcium but protein tyrosine phosphorylation is only associated with calcium.

Journal: Biology of reproduction 20030101

Title: The combi-targeting concept: a novel 3,3-disubstituted nitrosourea with EGFR tyrosine kinase inhibitory properties.

Journal: Cancer chemotherapy and pharmacology 20030101

Title: Subunit-specific modulation of KCNQ potassium channels by Src tyrosine kinase.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030101

Title: H1-A extracted from Cordyceps sinensis suppresses the proliferation of human mesangial cells and promotes apoptosis, probably by inhibiting the tyrosine phosphorylation of Bcl-2 and Bcl-XL.

Journal: The Journal of laboratory and clinical medicine 20030101

Title: HGF, MET, and matrix-related proteases in hepatocellular carcinoma, fibrolamellar variant, cirrhotic and normal liver.

Journal: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20030101

Title: FLT3 mutations in acute myeloid leukemia cell lines.

Journal: Leukemia 20030101

Title: Structural determinants of integrin recognition by talin.

Journal: Molecular cell 20030101

Title: Simultaneous detection of ACP1 and GC genotypes using PCR/SSCP.

Journal: Annals of human genetics 20030101

Title: The role of the ubiquitination-proteasome pathway in breast cancer: ubiquitin mediated degradation of growth factor receptors in the pathogenesis and treatment of cancer.

Journal: Breast cancer research : BCR 20030101

Title: Isolation of novel substrates using a tyrosine kinase overlay/in situ assay.

Journal: Methods in molecular biology (Clifton, N.J.) 20030101

Title: Assaying tyrosine phosphorylation of insulin receptor and insulin receptor substrates.

Journal: Methods in molecular medicine 20030101

Title: Measuring insulin-stimulated phosphatidyl-inositol 3-kinase activity.

Journal: Methods in molecular medicine 20030101

Title: [The role of tyrosine phosphorylation in the regulation of cell proliferation and differentiation in lower eukaryotes].

Journal: Tsitologiia 20030101

Title: A novel Leishmania infantum nuclear phosphoprotein Lepp12 which stimulates IL1-beta synthesis in THP-1 transfectants.

Journal: BMC microbiology 20030101

Title: Plasma levels of HER-2/neu, tumor type M2 pyruvate kinase and its tyrosine-phosphorylated metabolite in advanced breast cancer.

Journal: Anticancer research 20030101

Title: The 35 kDa acid metallophosphatase of the frog Rana esculenta liver: studies on its cellular localization and protein phosphatase activity.

Journal: Acta biochimica Polonica 20030101

Title: Protein phosphatase-2A regulates protein tyrosine phosphatase activity in Lewis lung carcinoma tumor variants.

Journal: Clinical & experimental metastasis 20030101

Title: Adhesion of endothelial cells to NOV is mediated by the integrins alphavbeta3 and alpha5beta1.

Journal: Journal of vascular research 20030101

Title: Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells.

Journal: BMC cancer 20030101

Title: The influence of the extracellular matrix on the morphology and intracellular pH of cultured astrocytes exposed to media lacking bicarbonate.

Journal: Neuroscience 20030101

Title: Role of gonadotropin-releasing hormone (GnRH) in ovarian cancer.

Journal: Reproductive biology and endocrinology : RB&E 20030101

Title: Changes in sperm phosphotyrosine proteins by human follicular fluid in mice.

Journal: Archives of andrology 20030101

Title: Gonadotropin releasing hormone analogue (GnRHa) alters the expression and activation of Smad in human endometrial epithelial and stromal cells.

Journal: Reproductive biology and endocrinology : RB&E 20030101

Title: FK506 attenuates the post-ischemic perturbation of protein kinases and tyrosine phosphorylation in the gerbil hippocampal CA1 sectors.

Journal: Acta neurochirurgica. Supplement 20030101

Title: Structure-based design of novel nonpeptide inhibitors of the Src SH2 domain:phosphotyrosine mimetics exploiting multifunctional group replacement chemistry.

Journal: Biopolymers 20030101

Title: Inhibition of lactate dehydrogenase C4 (LDH-C4) blocks capacitation of mouse sperm in vitro.

Journal: Cytogenetic and genome research 20030101

Title: T cell receptor-mediated signalling in T cells from multiple myeloma patients.

Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20030101

Title: Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle.

Journal: The Journal of biological chemistry 20021227

Title: Protein kinase C delta associates with the interleukin-6 receptor subunit glycoprotein (gp) 130 via Stat3 and enhances Stat3-gp130 interaction.

Journal: The Journal of biological chemistry 20021220

Title: Phosphoinositide binding by the pleckstrin homology domains of Ipl and Tih1.

Journal: The Journal of biological chemistry 20021220

Title: Lyn and Syk kinases are sequentially engaged in phagocytosis mediated by Fc gamma R.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20021215

Title: Autocrine activation of the hepatocyte growth factor receptor/met tyrosine kinase induces tumor cell motility by regulating pseudopodial protrusion.

Journal: The Journal of biological chemistry 20021213

Title: Design and use of a mammalian protein-protein interaction trap (MAPPIT).

Journal: Science's STKE : signal transduction knowledge environment 20021210

Title: Crystal structure and NMR studies of the apo SH2 domains of ZAP-70: two bikes rather than a tandem.

Journal: Biochemistry 20021203

Title: Internalization of inactive EGF receptor into endosomes and the subsequent activation of endosome-associated EGF receptors. Epidermal growth factor.

Journal: Science's STKE : signal transduction knowledge environment 20021203

Title: Design and synthesis of a beta-amino phosphotyrosyl mimetic suitably protected for peptide synthesis.

Journal: Bioorganic & medicinal chemistry letters 20021202

Title: Lipopolysaccharide-induced reductions in cellular coupling correlate with tyrosine phosphorylation of connexin 43.

Journal: Journal of cellular physiology 20021201

Title: Mechanism by which cAMP activates PI3-kinase and increases bile acid secretion in WIF-B9 cells.

Journal: American journal of physiology. Cell physiology 20021201

Title: Restoration of synapse formation in Musk mutant mice expressing a Musk/Trk chimeric receptor.

Journal: Development (Cambridge, England) 20021201

Title: Stimulated tyrosine phosphorylation of phosphatidylinositol 3-kinase causes acidic pH-induced contraction in spontaneously hypertensive rat aorta.

Journal: The Journal of pharmacology and experimental therapeutics 20021201

Title: A role for Grb2-associated binder-1 in growth hormone signaling.

Journal: Endocrinology 20021201

Title: Expression patterns of focal adhesion associated proteins in the developing retina.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20021201

Title: Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development.

Journal: Molecular endocrinology (Baltimore, Md.) 20021201

Title: Dual mechanism of signal transducer and activator of transcription 5 activation by the insulin receptor.

Journal: Molecular endocrinology (Baltimore, Md.) 20021201

Title: Characterization of morphological and cytoskeletal changes in trophoblast cells induced by insulin-like growth factor-I.

Journal: The Journal of clinical endocrinology and metabolism 20021201

Title: IgG-mediated signal transduction in canine mastocytoma-derived cells.

Journal: International archives of allergy and immunology 20021201

Title: Cellular signaling during the macrophage invasion by Trypanosoma cruzi.

Journal: Histochemistry and cell biology 20021201

Title: EDTA inhibits collagen-induced ATP+ADP secretion and tyrosine phosphorylation in platelets independently of Mg2+ chelation and decrease in pH.

Journal: Platelets 20021201

Title: Absence of functional insulin receptor substrate-3 (IRS-3) gene in humans.

Journal: Diabetologia 20021201

Title: Lyn kinase is activated following thrombopoietin stimulation of the megakaryocytic cell line B1647.

Journal: Haematologica 20021201

Title: Tyrosine kinase activity of nerve growth factor and estrogen in embryonic septal neurons cultured from the rat.

Journal: Neurochemical research 20021201

Title: Convulsive disorder and the genetics of signal transduction; a study of a low molecular weight protein tyrosine phosphatase in a pediatric sample.

Journal: Neuroscience letters 20021129

Title: SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells.

Journal: Cytokine 20021124

Title: Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis.

Journal: Oncogene 20021121

Title: The roles of phosphotyrosines-294, -404, and -451 in RET/PTC1-induced thyroid tumor formation.

Journal: Oncogene 20021121

Title: Ca2+ promotes erythrocyte band 3 tyrosine phosphorylation via dissociation of phosphotyrosine phosphatase from band 3.

Journal: The Biochemical journal 20021115

Title: ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2.

Journal: The Journal of biological chemistry 20021115

Title: PACAP-27 tyrosine phosphorylates mitogen activated protein kinase and increases VEGF mRNAs in human lung cancer cells.

Journal: Regulatory peptides 20021115

Title: Cloning of a novel phosphotyrosine binding domain containing molecule, Odin, involved in signaling by receptor tyrosine kinases.

Journal: Oncogene 20021114

Title: In vivo regulation of phosphoinositide 3-kinase in retina through light-induced tyrosine phosphorylation of the insulin receptor beta-subunit.

Journal: The Journal of biological chemistry 20021108

Title: Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras.

Journal: The Journal of biological chemistry 20021108

Title: Identification and characterization of two novel low-molecular-weight dual specificity phosphatases.

Journal: Biochemical and biophysical research communications 20021108

Title: Elevated c-Src is linked to altered cell-matrix adhesion rather than proliferation in KM12C human colorectal cancer cells.

Journal: British journal of cancer 20021104

Title: Low Mr phosphotyrosine protein phosphatase associates and dephosphorylates p125 focal adhesion kinase, interfering with cell motility and spreading.

Journal: The Journal of biological chemistry 20021101

Title: Valosine containing protein is a substrate of cAMP-activated boar sperm tyrosine kinase.

Journal: Molecular reproduction and development 20021101

Title: Redistribution of ERK/MAP kinase to uropod-like structures in interleukin-3-induced cell shape changes.

Journal: Immunology letters 20021101

Title: Characterization of an ecto-phosphatase activity in the human parasite Trichomonas vaginalis.

Journal: Parasitology research 20021101

Title: Evolution of catalytic antibody repertoire in autoimmune mice.

Journal: Journal of immunological methods 20021101

Title: The Src homology 2 domain-containing inositol 5-phosphatase negatively regulates Fcgamma receptor-mediated phagocytosis through immunoreceptor tyrosine-based activation motif-bearing phagocytic receptors.

Journal: Blood 20021101

Title: A new and recurrent activating length mutation in exon 20 of the FLT3 gene in acute myeloid leukemia.

Journal: Blood 20021101

Title: Insulin stimulates spreading of skeletal muscle cells involving the activation of focal adhesion kinase, phosphatidylinositol 3-kinase and extracellular signal regulated kinases.

Journal: Journal of cellular physiology 20021101

Title: Imaging antigen-induced PI3K activation in T cells.

Journal: Nature immunology 20021101

Title: Regulation of the phosphotyrosine content of human sperm proteins by intracellular Ca2+: role of Ca2+-adenosine triphosphatases.

Journal: Biology of reproduction 20021101

Title: The increased bone mass in deltaFosB transgenic mice is independent of circulating leptin levels.

Journal: Endocrinology 20021101

Title: Comparative proteome bioinformatics: identification of a whole complement of putative protein tyrosine kinases in the model flowering plant Arabidopsis thaliana.

Journal: Proteomics 20021101

Title: Characterization of YM-90709 as a novel antagonist which inhibits the binding of interleukin-5 to interleukin-5 receptor.

Journal: International immunopharmacology 20021101

Title: [Changes of protein tyrosine phosphorylation in erythrocyte band 3 glucose-6-phosphate dehydrogenase deficiency].

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20021101

Title: Signal transduction through tyrosine-phosphorylated carboxy-terminal fragments of APP via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain.

Journal: Annals of the New York Academy of Sciences 20021101

Title: Secretory activity of boar seminal vesicle glands.

Journal: Reproductive biology 20021101

Title: Production of antibodies that recognize specific tyrosine-phosphorylated peptides.

Journal: Current protocols in immunology 20021101

Title: Substrate conformational restriction and CD45-catalyzed dephosphorylation of tail tyrosine-phosphorylated Src protein.

Journal: The Journal of biological chemistry 20021025

Title: Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces specific phosphorylation of ErbB2 and enhances expression of p27(kip), but does not activate mitogen-activated kinase or protein kinaseB/Akt pathways.

Journal: Oncogene 20021024

Title: Chicken anemia virus VP2 is a novel dual specificity protein phosphatase.

Journal: The Journal of biological chemistry 20021018

Title: Regulation of the EphA2 kinase by the low molecular weight tyrosine phosphatase induces transformation.

Journal: The Journal of biological chemistry 20021018

Title: The N-terminal SH2 domains of Syk and ZAP-70 mediate phosphotyrosine-independent binding to integrin beta cytoplasmic domains.

Journal: The Journal of biological chemistry 20021018

Title: Capacitation-like alterations in cooled boar spermatozoa: assessment by the chlortetracycline staining assay and immunodetection of tyrosine-phosphorylated sperm proteins.

Journal: Animal reproduction science 20021016

Title: Analysis of tyrosine phosphorylation sites in signaling molecules by a phosphotyrosine-specific immonium ion scanning method.

Journal: Science's STKE : signal transduction knowledge environment 20021015

Title: Negative regulation of urokinase-type plasminogen activator production through FGF-2-mediated activation of phosphoinositide 3-kinase.

Journal: Oncogene 20021010

Title: Design and characterization of non-phosphopeptide inhibitors for Src family SH2 domains.

Journal: Bioorganic & medicinal chemistry letters 20021007

Title: Development of a phosphatase-stable phosphotyrosyl mimetic suitably protected for the synthesis of high-affinity Grb2 SH2 domain-binding ligands.

Journal: Bioorganic & medicinal chemistry letters 20021007

Title: Altered biological activity associated with C-terminal modifications of IL-7.

Journal: Cytokine 20021007

Title: Insight into the role of low molecular weight phosphotyrosine phosphatase (LMW-PTP) on platelet-derived growth factor receptor (PDGF-r) signaling. LMW-PTP controls PDGF-r kinase activity through TYR-857 dephosphorylation.

Journal: The Journal of biological chemistry 20021004

Title: Secretin regulates paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20021001

Title: Interferon-gamma activates EGF receptor and increases TGF-alpha in T84 cells: implications for chloride secretion.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20021001

Title: The SPOT technique as a tool for studying protein tyrosine phosphatase substrate specificities.

Journal: Protein science : a publication of the Protein Society 20021001

Title: Myelin proteolipid protein, basic protein, the small isoform of myelin-associated glycoprotein, and p42MAPK are associated in the Triton X-100 extract of central nervous system myelin.

Journal: Journal of neuroscience research 20021001

Title: Soy isoflavone genistein modulates cell cycle progression and induces apoptosis in HER-2/neu oncogene expressing human breast epithelial cells.

Journal: International journal of oncology 20021001

Title: IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20021001

Title: c-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitination.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20021001

Title: Staging and resetting T cell activation in SMACs.

Journal: Nature immunology 20021001

Title: Probing Src homology 2 domain ligand interactions by differential line broadening.

Journal: Biochemistry 20021001

Title: Two distinct phosphoinositide 3-kinases mediate polypeptide growth factor-stimulated PKB activation.

Journal: The EMBO journal 20021001

Title: A tumor suppressor homolog, AtPTEN1, is essential for pollen development in Arabidopsis.

Journal: The Plant cell 20021001

Title: SRC homology-2 inhibitors: peptidomimetic and nonpeptide.

Journal: Mini reviews in medicinal chemistry 20021001

Title: Development of a time-resolved fluorescent assay for measuring tyrosine-phosphorylated proteins in cells.

Journal: Analytical biochemistry 20021001

Title: Transforming growth factor-beta(1) augments granulocyte-macrophage colony-stimulating factor-induced proliferation of umbilical cord blood CD34(+) cells with an associated tyrosine phosphorylation of STAT5.

Journal: Experimental hematology 20021001

Title: Molecular mechanism involved in matrix dependent upregulation of matrix metalloproteinases in monocyte/macrophage.

Journal: Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) 20021001

Title: The docking protein FRS2alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors.

Journal: Molecular cell 20021001

Title: Grb2 is a key mediator of helicobacter pylori CagA protein activities.

Journal: Molecular cell 20021001

Title: Arsenate reductases in prokaryotes and eukaryotes.

Journal: Environmental health perspectives 20021001

Title: Expression of epidermal growth factor receptor and related phosphorylation proteins in hypertrophic scars and normal skin.

Journal: Chinese medical journal 20021001

Title: Inhibition of bovine kidney low molecular mass phosphotyrosine protein phosphatase by uric acid.

Journal: Journal of enzyme inhibition and medicinal chemistry 20021001

Title: SHP1 protein-tyrosine phosphatase regulates HoxA10 DNA binding and transcriptional repression activity in undifferentiated myeloid cells.

Journal: The Journal of biological chemistry 20020927

Title: Side-chain dynamics of the SAP SH2 domain correlate with a binding hot spot and a region with conformational plasticity.

Journal: Journal of molecular biology 20020920

Title: Tyrosine phosphorylation of clathrin heavy chain under oxidative stress.

Journal: Biochemical and biophysical research communications 20020920

Title: PrpE, a PPP protein phosphatase from Bacillus subtilis with unusual substrate specificity.

Journal: The Biochemical journal 20020915

Title: Peroxynitrite signaling: receptor tyrosine kinases and activation of stress-responsive pathways.

Journal: Free radical biology & medicine 20020915

Title: Regulation of phosphatidylinositol 3-kinase activity and phosphatidylinositol 3,4,5-trisphosphate accumulation by neutrophil priming agents.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020915

Title: Sck is expressed in endothelial cells and participates in vascular endothelial growth factor-induced signaling.

Journal: Oncogene 20020912

Title: Antagonistic and agonistic effects of quinazoline tyrosine kinase inhibitors on mutant EGF receptor function.

Journal: International journal of cancer 20020910

Title: CD4 is active as a signaling molecule on the human monocytic cell line Thp-1.

Journal: Experimental cell research 20020910

Title: Enumeration, phenotyping, and identification of activation events in conjugates between T cells and antigen-presenting cells by flow cytometry.

Journal: Science's STKE : signal transduction knowledge environment 20020910

Title: Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc.

Journal: British journal of cancer 20020909

Title: Oxidant-induced vascular endothelial growth factor expression in human keratinocytes and cutaneous wound healing.

Journal: The Journal of biological chemistry 20020906

Title: Nitration of PECAM-1 ITIM tyrosines abrogates phosphorylation and SHP-2 binding.

Journal: Biochemical and biophysical research communications 20020906

Title: Proteasome inhibitors regulate tyrosine phosphorylation of IRS-1 and insulin signaling in adipocytes.

Journal: Biochemical and biophysical research communications 20020906

Title: Nitric oxide-induced motility in aortic smooth muscle cells: role of protein tyrosine phosphatase SHP-2 and GTP-binding protein Rho.

Journal: Circulation research 20020906

Title: Stimulation of hepatic signal transducer and activator of transcription 5b by GH is not altered by 3-methylcholanthrene.

Journal: Endocrinology 20020901

Title: c-Cbl is a negative regulator of GH-stimulated STAT5-mediated transcription.

Journal: Endocrinology 20020901

Title: Differential expression of multiple isoforms of the ELKS mRNAs involved in a papillary thyroid carcinoma.

Journal: Genes, chromosomes & cancer 20020901

Title: Suppression of IL-4- and CD40-induced B-lymphocyte activation by intravenous immunoglobulin is not mediated through the inhibitory IgG receptor FcgammaRIIb.

Journal: The Journal of allergy and clinical immunology 20020901

Title: Novel peptide inhibitors for Grb2 SH2 domain and their detection by surface plasmon resonance.

Journal: The journal of peptide research : official journal of the American Peptide Society 20020901

Title: pp60(c-src) is a negative regulator of laminin-1-mediated neurite outgrowth in chick sensory neurons.

Journal: Molecular and cellular neurosciences 20020901

Title: Regulation and targets of receptor tyrosine kinases.

Journal: European journal of cancer (Oxford, England : 1990) 20020901

Title: Involvement of cell-cell interactions in the rapid stimulation of Cas tyrosine phosphorylation and Src kinase activity by transforming growth factor-beta 1.

Journal: The Journal of biological chemistry 20020830

Title: Regulation of signaling in B cells through the phosphorylation of Syk on linker region tyrosines. A mechanism for negative signaling by the Lyn tyrosine kinase.

Journal: The Journal of biological chemistry 20020830

Title: Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines.

Journal: Oncogene 20020829

Title: Density functional study of the mechanism of a tyrosine phosphatase: I. Intermediate formation.

Journal: Journal of the American Chemical Society 20020828

Title: Signal transduction through the T cell receptor is dynamically regulated by balancing kinase and phosphatase activities.

Journal: Biochemical and biophysical research communications 20020823

Title: The SH3 domain of Src can downregulate its kinase activity in the absence of the SH2 domain-pY527 interaction.

Journal: Biochemical and biophysical research communications 20020823

Title: General method for the synthesis of caged phosphopeptides: tools for the exploration of signal transduction pathways.

Journal: Organic letters 20020822

Title: Antibody-based fluorescence detection of kinase activity on a peptide array.

Journal: Bioorganic & medicinal chemistry letters 20020819

Title: Rational design of 4,5-disubstituted-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-ones as a novel class of inhibitors of epidermal growth factor receptor (EGF-R) and Her2(p185(erbB)) tyrosine kinases.

Journal: Bioorganic & medicinal chemistry letters 20020819

Title: Phosphotyrosine-specific phosphatase PTP-SL regulates the ERK5 signaling pathway.

Journal: The Journal of biological chemistry 20020816

Title: Functional interleukin-7 receptors (IL-7Rs) are expressed by marrow stromal cells: binding of IL-7 increases levels of IL-6 mRNA and secreted protein.

Journal: Blood 20020815

Title: TEL-JAK2 constitutively activates the extracellular signal-regulated kinase (ERK), stress-activated protein/Jun kinase (SAPK/JNK), and p38 signaling pathways.

Journal: Blood 20020815

Title: Constitutive activation of Jak/STAT proteins in Epstein-Barr virus-infected B-cell lines from patients with posttransplant lymphoproliferative disorder.

Journal: Transplantation 20020815

Title: Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking.

Journal: Biochemistry 20020813

Title: Intramolecular quenching of tryptophan fluorescence by the peptide bond in cyclic hexapeptides.

Journal: Journal of the American Chemical Society 20020807

Title: The Src-cortactin pathway is required for clustering of E-selectin and ICAM-1 in endothelial cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020801

Title: SH3 domain-mediated binding of the Drk protein to Dos is an important step in signaling of Drosophila receptor tyrosine kinases.

Journal: Mechanisms of development 20020801

Title: Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020801

Title: Phosphotyrosine - a novel marker for H1 horizontal cells in normal human retinas.

Journal: Experimental eye research 20020801

Title: Potentiation of insulin signaling in tissues of Zucker obese rats after acute and long-term treatment with PPARgamma agonists.

Journal: Diabetes 20020801

Title: Laminin alpha5 chain adhesion and signaling in conjunctival epithelial cells.

Journal: Investigative ophthalmology & visual science 20020801

Title: Phosphorylation of Hrs downstream of the epidermal growth factor receptor.

Journal: European journal of biochemistry 20020801

Title: Expression of junction-associated proteins differentiates mouse intestinal M cells from enterocytes.

Journal: Histochemistry and cell biology 20020801

Title: Phosphorylation by protein kinase CK2: a signaling switch for the caspase-inhibiting protein ARC.

Journal: Molecular cell 20020801

Title: Comparison of red wine extract and polyphenol constituents on endothelin-1 synthesis by cultured endothelial cells.

Journal: Clinical science (London, England : 1979) 20020801

Title: Tyrosine phosphorylation of the metabotropic glutamate receptor mGluR5 in striatal neurons.

Journal: Neuropharmacology 20020801

Title: Probing the phosphopeptide specificities of protein tyrosine phosphatases, SH2 and PTB domains with combinatorial library methods.

Journal: Current protein & peptide science 20020801

Title: Structural basis for inhibition of protein tyrosine phosphatases by Keggin compounds phosphomolybdate and phosphotungstate.

Journal: Experimental & molecular medicine 20020731

Title: Structural requirements for interaction of sodium channel beta 1 subunits with ankyrin.

Journal: The Journal of biological chemistry 20020719

Title: Mediation of the DCC apoptotic signal by DIP13 alpha.

Journal: The Journal of biological chemistry 20020719

Title: Mitogen-induced, FAK-dependent tyrosine phosphorylation of the SSeCKS scaffolding protein.

Journal: Experimental cell research 20020715

Title: Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord during the development and maintenance of inflammatory hyperalgesia.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020715

Title: Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP.

Journal: Biochemical and biophysical research communications 20020712

Title: Tk-PTP, protein tyrosine/serine phosphatase from hyperthermophilic archaeon Thermococcus kodakaraensis KOD1: enzymatic characteristics and identification of its substrate proteins.

Journal: Biochemical and biophysical research communications 20020712

Title: The common gamma chain (gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3.

Journal: Biochemistry 20020709

Title: Activation of ZAP-70 through specific dephosphorylation at the inhibitory Tyr-292 by the low molecular weight phosphotyrosine phosphatase (LMPTP).

Journal: The Journal of biological chemistry 20020705

Title: Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420.

Journal: The Journal of biological chemistry 20020705

Title: Src-dependent phosphorylation of the epidermal growth factor receptor on tyrosine 845 is required for zinc-induced Ras activation.

Journal: The Journal of biological chemistry 20020705

Title: The lipid peroxidation product 4-hydroxynonenal facilitates opening of voltage-dependent Ca2+ channels in neurons by increasing protein tyrosine phosphorylation.

Journal: The Journal of biological chemistry 20020705

Title: Determination of active concentrations and association and dissociation rate constants of interacting biomolecules: an analytical solution to the theory for kinetic and mass transport limitations in biosensor technology and its experimental verification.

Journal: Biochemistry 20020702

Title: Cellular signalling in arteriolar myogenic constriction: involvement of tyrosine phosphorylation pathways.

Journal: Clinical and experimental pharmacology & physiology 20020701

Title: Endothelin-induced myoplasmic Ca2+ responses and tyrosine phosphorylation in coronary smooth muscle.

Journal: Journal of cardiovascular pharmacology 20020701

Title: PTEN is a negative regulator of STAT3 activation in human papillomavirus-infected cells.

Journal: The Journal of general virology 20020701

Title: Regulation of the human sperm tyrosine kinase c-yes. Activation by cyclic adenosine 3',5'-monophosphate and inhibition by Ca(2+).

Journal: Biology of reproduction 20020701

Title: Localisation of somatostatin and somatostatin receptors in benign and malignant ovarian tumours.

Journal: British journal of cancer 20020701

Title: G(1)/S CDK is inhibited to restrain mitotic onset when DNA replication is blocked in fission yeast.

Journal: The EMBO journal 20020701

Title: SRC-1 and Wnt signaling act together to specify endoderm and to control cleavage orientation in early C. elegans embryos.

Journal: Developmental cell 20020701

Title: Juvenile hormone stimulated tyrosine kinase-mediated protein phosphorylation in the CNS of the silk worm, Bombyx mori.

Journal: Archives of insect biochemistry and physiology 20020701

Title: A new type of antimetastatic peptide derived from fibronectin.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020701

Title: Expression and functional analysis of the anaplastic lymphoma kinase (ALK) gene in tumor cell lines.

Journal: International journal of cancer 20020701

Title: NO attenuates insulin signaling and motility in aortic smooth muscle cells via protein tyrosine phosphatase 1B-mediated mechanism.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20020701

Title: Subproteomics analysis of phosphorylated proteins: application to the study of B-lymphoblasts from a patient with Scott syndrome.

Journal: Proteomics 20020701

Title: Hypothermic reperfusion after cardiac arrest augments brain-derived neurotrophic factor activation.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020701

Title: A novel precursor ion discovery method on a hybrid quadrupole orthogonal acceleration time-of-flight (Q-TOF) mass spectrometer for studying protein phosphorylation.

Journal: Journal of the American Society for Mass Spectrometry 20020701

Title: Dynamic characterization of the molecular events during in vitro epidermal wound healing.

Journal: The Journal of investigative dermatology 20020701

Title: A mass spectrometry-based proteomic approach for identification of serine/threonine-phosphorylated proteins by enrichment with phospho-specific antibodies: identification of a novel protein, Frigg, as a protein kinase A substrate.

Journal: Molecular & cellular proteomics : MCP 20020701

Title: Proteomic analysis of protein phosphorylations in heat shock response and thermotolerance.

Journal: The Journal of biological chemistry 20020628

Title: Thrombin-stimulated Pyk2 phosphorylation in human endothelium is dependent on intracellular calcium and independent of protein kinase C and Src kinases.

Journal: Biochemical and biophysical research communications 20020628

Title: G120K-PEG, a human GH antagonist, decreases GH signal transduction in the liver of mice.

Journal: Molecular and cellular endocrinology 20020628

Title: Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation.

Journal: Cell 20020628

Title: Transformation of Ba/F3 cells and Rat-1 cells by ETV6/ARG.

Journal: Oncogene 20020627

Title: Phosphorylated tyrosine-containing proteins in primary lung cancer correlates with proliferation and prognosis.

Journal: British journal of cancer 20020617

Title: Differential role of glycolipid-enriched membrane domains in glycoprotein VI- and integrin-mediated phospholipase Cgamma2 regulation in platelets.

Journal: The Biochemical journal 20020615

Title: Comparative expression profiles of Trk receptors and Shc-related phosphotyrosine adapters during retinal development: potential roles of N-Shc/ShcC in brain-derived neurotrophic factor signal transduction and modulation.

Journal: Journal of neuroscience research 20020615

Title: Mitotic activation of protein-tyrosine phosphatase alpha and regulation of its Src-mediated transforming activity by its sites of protein kinase C phosphorylation.

Journal: The Journal of biological chemistry 20020614

Title: The phosphotyrosine binding-like domain of talin activates integrins.

Journal: The Journal of biological chemistry 20020614

Title: SAR and X-ray. A new approach combining fragment-based screening and rational drug design: application to the discovery of nanomolar inhibitors of Src SH2.

Journal: Journal of medicinal chemistry 20020606

Title: First artificial receptors and chemosensors toward phosphorylated peptide in aqueous solution.

Journal: Journal of the American Chemical Society 20020605

Title: Clustering the mast cell function-associated antigen (MAFA) leads to tyrosine phosphorylation of p62Dok and SHIP and affects RBL-2H3 cell cycle.

Journal: Immunology letters 20020603

Title: Receptor tyrosine phosphatase, CD45 binds galectin-1 but does not mediate its apoptotic signal in T cell lines.

Journal: Immunology letters 20020603

Title: Different proteins are phosphorylated under acidic environments in Jurkat cells.

Journal: Immunology letters 20020603

Title: Effect of hyperglycemia on the basal cytosolic free calcium level, calcium signal and tyrosine-phosphorylation in human T-cells.

Journal: Immunology letters 20020603

Title: Developmental differences in B cell receptor-induced signal transduction.

Journal: Cellular signalling 20020601

Title: Focal adhesion kinase tyrosine phosphorylation is associated with myogenesis and modulated by insulin.

Journal: Cell proliferation 20020601

Title: Phosphotyrosine proteins in platelets from patients with storage pool disease: direct relation between granule defects and defective signal transduction.

Journal: Haematologica 20020601

Title: Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and glucokinase genes in rat hepatocytes.

Journal: Diabetes 20020601

Title: Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans.

Journal: Diabetes 20020601

Title: Female rats do not exhibit free fatty acid-induced insulin resistance.

Journal: Diabetes 20020601

Title: Differential effects of tumor necrosis factor-alpha on protein kinase C isoforms alpha and delta mediate inhibition of insulin receptor signaling.

Journal: Diabetes 20020601

Title: Ganglioside GM3 activates ERKs in human lymphocytic cells.

Journal: Journal of lipid research 20020601

Title: Rho and basic fibroblast growth factor involvement in centrosome redistribution and actin microfilament remodeling during early endothelial wound repair.

Journal: Journal of vascular surgery 20020601

Title: Expression and characterization of the Drosophila X11-like/Mint protein during neural development.

Journal: Journal of neurochemistry 20020601

Title: Altered arachidonic acid biosynthesis and antioxidant protection mechanisms in Schwann cells grown in elevated glucose.

Journal: Journal of neurochemistry 20020601

Title: Phosphorylation of the movement protein of cucumber mosaic virus in transgenic tobacco plants.

Journal: Virus genes 20020601

Title: Identification of the phosphotyrosine proteome from thrombin activated platelets.

Journal: Proteomics 20020601

Title: Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation.

Journal: Immunity 20020601

Title: Basic fibroblast growth factor: effects on matrix remodeling, receptor expression, and transduction pathway in human periosteal fibroblasts with FGFR2 gene mutation.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20020601

Title: Regulation of IRS-1/SHP2 interaction and AKT phosphorylation in animal models of insulin resistance.

Journal: Endocrine 20020601

Title: Tyrosine phosphatase CD45 regulates hydrogen peroxide-induced calcium mobilization in B cells.

Journal: Antioxidants & redox signaling 20020601

Title: Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade.

Journal: The Journal of biological chemistry 20020531

Title: Insulin-like growth factor-binding protein-3 activates a phosphotyrosine phosphatase. Effects on the insulin-like growth factor signaling pathway.

Journal: The Journal of biological chemistry 20020531

Title: Phosphatidylinositol 3-kinase is required for insulin-stimulated tyrosine phosphorylation of Shc in 3T3-L1 adipocytes.

Journal: The Journal of biological chemistry 20020524

Title: Amyloid precursor protein processing is separately regulated by protein kinase C and tyrosine kinase in human astrocytes.

Journal: Neuroscience letters 20020524

Title: Molecular docking and high-throughput screening for novel inhibitors of protein tyrosine phosphatase-1B.

Journal: Journal of medicinal chemistry 20020523

Title: Opposite effects of different doses of MCSF on ERK phosphorylation and cell proliferation in macrophages.

Journal: Oncogene 20020523

Title: Phosphoinositide 3-kinases in lysophosphatidic acid signaling: regulation and cross-talk with the Ras/mitogen-activated protein kinase pathway.

Journal: Biochimica et biophysica acta 20020523

Title: Plasma membrane phospholipid scramblase 1 is enriched in lipid rafts and interacts with the epidermal growth factor receptor.

Journal: Biochemistry 20020521

Title: Drac1 and Crumbs participate in amnioserosa morphogenesis during dorsal closure in Drosophila.

Journal: Journal of cell science 20020515

Title: New perspectives in PDGF receptor downregulation: the main role of phosphotyrosine phosphatases.

Journal: Journal of cell science 20020515

Title: SHP-1- and phosphotyrosine-independent inhibitory signaling by a killer cell Ig-like receptor cytoplasmic domain in human NK cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020515

Title: Localized exocytosis of primary (lysosomal) granules during phagocytosis: role of Ca2+-dependent tyrosine phosphorylation and microtubules.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020515

Title: Labeling of antibodies by in situ modification of thiol groups generated from selenol-catalyzed reduction of native disulfide bonds.

Journal: Analytical biochemistry 20020515

Title: Cleavage properties of an archaeal site-specific recombinase, the SSV1 integrase.

Journal: The Journal of biological chemistry 20020510

Title: FRS2 PTB domain conformation regulates interactions with divergent neurotrophic receptors.

Journal: The Journal of biological chemistry 20020510

Title: Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc.

Journal: The Journal of biological chemistry 20020510

Title: E-selectin modulates the malignant properties of T84 colon carcinoma cells.

Journal: Biochemical and biophysical research communications 20020510

Title: Discovery of highly potent Src SH2 binders: structure-activity studies and X-ray structures.

Journal: Bioorganic & medicinal chemistry letters 20020506

Title: Small ligands interacting with the phosphotyrosine binding pocket of the Src SH2 protein.

Journal: Bioorganic & medicinal chemistry letters 20020506

Title: Protein mapping in rat basophilic leukaemia cells.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020505

Title: Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation.

Journal: The Journal of biological chemistry 20020503

Title: Platelet-derived growth factor (PDGF)-induced tyrosine phosphorylation of the low density lipoprotein receptor-related protein (LRP). Evidence for integrated co-receptor function betwenn LRP and the PDGF.

Journal: The Journal of biological chemistry 20020503

Title: Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolae.

Journal: The Journal of biological chemistry 20020503

Title: Experimental and calculated shift in pK(a) upon binding of phosphotyrosine peptide to the SH2 domain of p56(lck).

Journal: Bioorganic & medicinal chemistry 20020501

Title: Ammonia induces MK-801-sensitive nitration and phosphorylation of protein tyrosine residues in rat astrocytes.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020501

Title: Cr supplementation decreases tyrosine phosphorylation of the CreaT in skeletal muscle during sepsis.

Journal: American journal of physiology. Endocrinology and metabolism 20020501

Title: Lymphocyte binding to MAdCAM-1 via alpha4beta7 integrin activates a signal transduction pathway involving tyrosine phosphorylation of paxillin and p105(Cas-L).

Journal: Immunology letters 20020501

Title: Adrenocorticotropin/cyclic adenosine 3',5'-monophosphate-mediated transcription of the human CYP17 gene in the adrenal cortex is dependent on phosphatase activity.

Journal: Endocrinology 20020501

Title: CTLA-4 suppresses proximal TCR signaling in resting human CD4(+) T cells by inhibiting ZAP-70 Tyr(319) phosphorylation: a potential role for tyrosine phosphatases.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020501

Title: Downstream of kinase, p62(dok), is a mediator of Fc gamma IIB inhibition of Fc epsilon RI signaling.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020501

Title: Stat5B shuttles between cytoplasm and nucleus in a cytokine-dependent and -independent manner.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020501

Title: The adapter molecule Gab2 regulates Fc epsilon RI-mediated signal transduction in mast cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020501

Title: SH3-dependent stimulation of Src-family kinase autophosphorylation without tail release from the SH2 domain in vivo.

Journal: Nature structural biology 20020501

Title: Advanced glycation end product precursors impair epidermal growth factor receptor signaling.

Journal: Diabetes 20020501

Title: Heterologous expression and catalytic properties of the C-terminal domain of starfish cdc25 dual-specificity phosphatase, a cell cycle regulator.

Journal: Journal of biochemistry 20020501

Title: Persistent defect in transmitter release and synapsin phosphorylation in cerebral cortex after transient moderate ischemic injury.

Journal: Stroke 20020501

Title: Expression of c-kit protein in proliferative lesions of human breast: sexual difference and close association with phosphotyrosine status.

Journal: Journal of cancer research and clinical oncology 20020501

Title: A rapid extraction procedure of human hair proteins and identification of phosphorylated species.

Journal: Biological & pharmaceutical bulletin 20020501

Title: Methods of analysis for chemicals that promote/disrupt cellular signaling.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20020501

Title: Expression and localization of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.

Journal: Research in microbiology 20020501

Title: Retinoic acid-induced growth arrest and differentiation: retinoic acid up-regulates CD32 (Fc gammaRII) expression, the ectopic expression of which retards the cell cycle.

Journal: Molecular cancer therapeutics 20020501

Title: c-Cbl associates directly with the C-terminal tail of the receptor for the macrophage colony-stimulating factor, c-Fms, and down-modulates this receptor but not the viral oncogene v-Fms.

Journal: The Journal of biological chemistry 20020426

Title: The fate of biodegradable microspheres injected into rat brain.

Journal: Neuroscience letters 20020426

Title: Investigation of potential bioisosteric replacements for the carboxyl groups of peptidomimetic inhibitors of protein tyrosine phosphatase 1B: identification of a tetrazole-containing inhibitor with cellular activity.

Journal: Journal of medicinal chemistry 20020425

Title: Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling.

Journal: The Journal of biological chemistry 20020419

Title: Local actin polymerization and dynamin recruitment in SV40-induced internalization of caveolae.

Journal: Science (New York, N.Y.) 20020419

Title: Repair by Src kinase of function-impaired RET with multiple endocrine neoplasia type 2A mutation with substitutions of tyrosines in the COOH-terminal kinase domain for phenylalanine.

Journal: Cancer research 20020415

Title: STAT3 deficiency in keratinocytes leads to compromised cell migration through hyperphosphorylation of p130(cas).

Journal: The Journal of biological chemistry 20020412

Title: Dominant negative knockout of p53 abolishes ErbB2-dependent apoptosis and permits growth acceleration in human breast cancer cells.

Journal: British journal of cancer 20020408

Title: Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP).

Journal: The Journal of biological chemistry 20020405

Title: Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathway.

Journal: The Journal of biological chemistry 20020405

Title: Motif analysis of the tumor suppressor gene MMAC/PTEN identifies tyrosines critical for tumor suppression and lipid phosphatase activity.

Journal: Oncogene 20020404

Title: Characterization and location of Src-dependent tyrosine phosphorylation in rat brain mitochondria.

Journal: Biochimica et biophysica acta 20020403

Title: Differential involvement of Src family kinases in pervanadate-mediated responses in rat myometrial cells.

Journal: Cellular signalling 20020401

Title: Decrease in growth factor receptors after treatment with serine protease inhibitor ONO-3403.

Journal: International journal of oncology 20020401

Title: Human CD38 and CD16 are functionally dependent and physically associated in natural killer cells.

Journal: Blood 20020401

Title: Protein tyrosine phosphorylation in T cell signaling.

Journal: Frontiers in bioscience : a journal and virtual library 20020401

Title: Soluble fibrinogen modulates neutrophil functionality through the activation of an extracellular signal-regulated kinase-dependent pathway.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020401

Title: Inhibitors of receptor tyrosine kinases do not suppress progesterone-induced [Ca2+]i signalling in human spermatozoa.

Journal: Molecular human reproduction 20020401

Title: Insulin resistance, defective insulin receptor substrate 2-associated phosphatidylinositol-3' kinase activation, and impaired atypical protein kinase C (zeta/lambda) activation in myotubes from obese patients with impaired glucose tolerance.

Journal: Diabetes 20020401

Title: Cell density and N-cadherin interactions regulate cell proliferation in the sensory epithelia of the inner ear.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020401

Title: PAF-stimulated protein tyrosine phosphorylation in hippocampus: involvement of NO synthase.

Journal: Neurochemical research 20020401

Title: Cyclin G recruits PP2A to dephosphorylate Mdm2.

Journal: Molecular cell 20020401

Title: Comparison of alterations in insulin signalling pathway in adipocytes from Type II diabetic pregnant women and women with gestational diabetes mellitus.

Journal: Diabetologia 20020401

Title: Overexpression of ganglioside GM1 results in the dispersion of platelet-derived growth factor receptor from glycolipid-enriched microdomains and in the suppression of cell growth signals.

Journal: The Journal of biological chemistry 20020329

Title: The catalytic mechanism of Cdc25A phosphatase.

Journal: The Journal of biological chemistry 20020329

Title: Constitutive activation of Stat3alpha in brain tumors: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2).

Journal: Oncogene 20020327

Title: Design and characterization of an improved protein tyrosine phosphatase substrate-trapping mutant.

Journal: Biochemistry 20020326

Title: Identification of a new segment involved in cagA 3' region variation of Helicobacter pylori.

Journal: FEMS immunology and medical microbiology 20020325

Title: Coexpression of oncostatin M and its receptors and evidence for STAT3 activation in human ovarian carcinomas.

Journal: Cytokine 20020321

Title: Endosomal proteolysis of internalized insulin at the C-terminal region of the B chain by cathepsin D.

Journal: The Journal of biological chemistry 20020315

Title: Fibroblast growth factor receptor 1 phosphotyrosine 766: molecular target for prevention of progression of prostate tumors to malignancy.

Journal: Cancer research 20020315

Title: SHP-2 is involved in heterodimer specific loss of phosphorylation of Tyr771 in the PDGF beta-receptor.

Journal: Oncogene 20020314

Title: Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin.

Journal: The Journal of biological chemistry 20020308

Title: Specificity of interleukin-2 receptor gamma chain superfamily cytokines is mediated by insulin receptor substrate-dependent pathway.

Journal: The Journal of biological chemistry 20020308

Title: Overexpression of protein-tyrosine phosphatase PTP sigma is linked to impaired glucose-induced insulin secretion in hereditary diabetic Goto-Kakizaki rats.

Journal: Biochemical and biophysical research communications 20020308

Title: Activation of STAT5 triggers proliferation and contributes to anti-apoptotic signalling mediated by the oncogenic Xmrk kinase.

Journal: Oncogene 20020307

Title: Membrane-anchored Cbl suppresses Hck protein-tyrosine kinase mediated cellular transformation.

Journal: Oncogene 20020307

Title: Structural basis for the recognition of a bisphosphorylated MAP kinase peptide by human VHR protein Phosphatase.

Journal: Biochemistry 20020305

Title: Insulin receptor substrate-3 functions as transcriptional activator in the nucleus.

Journal: The Journal of biological chemistry 20020301

Title: Growth inhibition and apoptosis of myeloma cells by the CDK inhibitor flavopiridol.

Journal: Leukemia research 20020301

Title: Changes in membrane microenvironment and signal transduction in platelets from NIDDM patients-a pilot study.

Journal: Clinica chimica acta; international journal of clinical chemistry 20020301

Title: N-3 polyunsaturated fatty acids prevent the defect of insulin receptor signaling in muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20020301

Title: From structure to function: YrbI from Haemophilus influenzae (HI1679) is a phosphatase.

Journal: Proteins 20020301

Title: Fermented wheat germ extract induces apoptosis and downregulation of major histocompatibility complex class I proteins in tumor T and B cell lines.

Journal: International journal of oncology 20020301

Title: An immunohistochemical approach to monitor the prolactin-induced activation of the JAK2/STAT5 pathway in pancreatic islets of Langerhans.

Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20020301

Title: Ecdysone-inducible expression of oncogenic Ha-Ras in NIH 3T3 cells leads to transient nuclear localization of activated extracellular signal-regulated kinase regulated by mitogen-activated protein kinase phosphatase-1.

Journal: The Biochemical journal 20020301

Title: Phosphorylation of the N-terminal and C-terminal CD3-epsilon-ITAM tyrosines is differentially regulated in T cells.

Journal: Biochemical and biophysical research communications 20020301

Title: Regulation of angiopoietin and Tie-2 receptor expression in non-reproductive tissues by estrogen.

Journal: Steroids 20020301

Title: Receptor-facilitated antigen presentation requires the recruitment of B cell linker protein to Igalpha.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020301

Title: Lipid raft heterogeneity in human peripheral blood T lymphoblasts: a mechanism for regulating the initiation of TCR signal transduction.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020301

Title: Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes.

Journal: Diabetes 20020301

Title: Interdependence of steroidogenesis and shape changes in Y1 adrenocortical cells: studies with inhibitors of phosphoprotein phosphatases.

Journal: The Journal of endocrinology 20020301

Title: 14-3-3 facilitates insulin-stimulated intracellular trafficking of insulin receptor substrate 1.

Journal: Molecular endocrinology (Baltimore, Md.) 20020301

Title: Retinoic acid increases proliferation rate of GL-15 glioma cells, involving activation of STAT-3 transcription factor.

Journal: Journal of neuroscience research 20020301

Title: Fragmentation of phosphopeptides by atmospheric pressure MALDI and ESI/Ion trap mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry 20020301

Title: A tyrosine-phosphorylated 12-amino-acid sequence of enteropathogenic Escherichia coli Tir binds the host adaptor protein Nck and is required for Nck localization to actin pedestals.

Journal: Molecular microbiology 20020301

Title: Protein kinases activities in erythrocyte membranes of asphyxiated newborns.

Journal: Clinical biochemistry 20020301

Title: Phosphotyrosine-binding domains in signal transduction.

Journal: Nature reviews. Molecular cell biology 20020301

Title: Inhibition of lymphocyte kinase Lck and phosphatidylinositol 3-kinase by a novel immunosuppressant, lymphostin.

Journal: Bioscience, biotechnology, and biochemistry 20020301

Title: Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2.

Journal: The Journal of biological chemistry 20020222

Title: Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells.

Journal: Oncogene 20020221

Title: PTEN regulates tumor cell adhesion of colon carcinoma cells under dynamic conditions of fluid flow.

Journal: Oncogene 20020221

Title: Can we infer peptide recognition specificity mediated by SH3 domains?

Journal: FEBS letters 20020220

Title: PTB or not PTB -- that is the question.

Journal: FEBS letters 20020220

Title: WaaP of Pseudomonas aeruginosa is a novel eukaryotic type protein-tyrosine kinase as well as a sugar kinase essential for the biosynthesis of core lipopolysaccharide.

Journal: The Journal of biological chemistry 20020215

Title: Lyn tyrosine kinase is important for IL-5-stimulated eosinophil differentiation.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020215

Title: Regulation of postaggregation events induced by protease-activated receptor 1 ligation in human platelets: evidence of differential signaling pathways.

Journal: Archives of biochemistry and biophysics 20020215

Title: Dissection of the energetic coupling across the Src SH2 domain-tyrosyl phosphopeptide interface.

Journal: Journal of molecular biology 20020215

Title: Dephosphorylation failure of tyrosine-phosphorylated STAT1 in IFN-stimulated Sendai virus C protein-expressing cells.

Journal: Virology 20020215

Title: The kinase-null EphB6 receptor undergoes transphosphorylation in a complex with EphB1.

Journal: The Journal of biological chemistry 20020208

Title: Human endothelial Pyk2 is expressed in two isoforms and associates with paxillin and p130Cas.

Journal: Biochemical and biophysical research communications 20020208

Title: C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus.

Journal: Oncogene 20020207

Title: Calcium-dependent activation of Pyk2 by hypoxia.

Journal: Cellular signalling 20020201

Title: Regulation of phospholipase C-gamma 2 via phosphatidylinositol 3-kinase in macrophages.

Journal: Cellular signalling 20020201

Title: Erythropoietin receptor-dependent erythroid colony-forming unit development: capacities of Y343 and phosphotyrosine-null receptor forms.

Journal: Blood 20020201

Title: Autoinhibitory mechanisms in receptor tyrosine kinases.

Journal: Frontiers in bioscience : a journal and virtual library 20020201

Title: Requirement of Ca(2+) and PKCdelta for Janus kinase 2 activation by angiotensin II: involvement of PYK2.

Journal: Molecular endocrinology (Baltimore, Md.) 20020201

Title: Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele.

Journal: Cancer research 20020201

Title: Tumor necrosis factor alpha stimulates invasion of Src-activated intestinal cells.

Journal: Gastroenterology 20020201

Title: Identification of an IGF-1R kinase regulatory phosphatase using the fission yeast Schizosaccharomyces pombe and a GFP tagged IGF-1R in mammalian cells.

Journal: Molecular pathology : MP 20020201

Title: Detection of dual TEL-ABL transcripts and a Tel-Abl protein containing phosphotyrosine in a chronic myeloid leukemia patient.

Journal: Leukemia 20020201

Title: Phosphorylation and dephosphorylation of histidine residues in proteins.

Journal: European journal of biochemistry 20020201

Title: Phosphopeptide detection and sequencing by matrix-assisted laser desorption/ionization quadrupole time-of-flight tandem mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20020201

Title: Low density detergent-insoluble membrane of Xenopus eggs: subcellular microdomain for tyrosine kinase signaling in fertilization.

Journal: Development (Cambridge, England) 20020201

Title: Induction of chondrocyte growth arrest by FGF: transcriptional and cytoskeletal alterations.

Journal: Journal of cell science 20020201

Title: Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family.

Journal: Immunogenetics 20020201

Title: Targeting the EGF receptor in ovarian cancer with the tyrosine kinase inhibitor ZD 1839 ('Iressa').

Journal: British journal of cancer 20020201

Title: Endothelin-1--induced enhancement of coronary smooth muscle contraction via MAPK-dependent and MAPK-independent [Ca(2+)](i) sensitization pathways.

Journal: Hypertension (Dallas, Tex. : 1979) 20020201

Title: Overview of rationale and clinical trials with signal transduction inhibitors in lung cancer.

Journal: Seminars in oncology 20020201

Title: Analysis of genetic and epigenetic alterations of the PTEN gene in gastric cancer.

Journal: Virchows Archiv : an international journal of pathology 20020201

Title: Assay and screening methods for bioactive substances based on cellular signaling pathways.

Journal: Journal of biotechnology 20020201

Title: Role of KCNQ1 in the cell swelling-induced enhancement of the slowly activating delayed rectifier K(+) current.

Journal: The Japanese journal of physiology 20020201

Title: Enriched levels of erythropoietin in human umbilical cord blood stimulate hematopoietic progenitor cells.

Journal: Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) 20020201

Title: Production of antibodies that recognize specific tyrosine-phosphorylated peptides.

Journal: Current protocols in cell biology 20020201

Title: Regulation of p73 by c-Abl through the p38 MAP kinase pathway.

Journal: Oncogene 20020131

Title: Sendai virus C protein impairs both phosphorylation and dephosphorylation processes of Stat1.

Journal: FEBS letters 20020130

Title: Reduced expression of EphrinA1 (EFNA1) inhibits three-dimensional growth of HT29 colon carcinoma cells.

Journal: Cancer letters 20020125

Title: SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein.

Journal: Science (New York, N.Y.) 20020125

Title: The upper cytokine-binding module and the Ig-like domain of the leukaemia inhibitory factor (LIF) receptor are sufficient for a functional LIF receptor complex.

Journal: Journal of molecular biology 20020125

Title: Involvement of phosphorylation of Tyr-31 and Tyr-118 of paxillin in MM1 cancer cell migration.

Journal: International journal of cancer 20020120

Title: Significance of phosphotyrosine proteins, Bcl-2 and p53 for apoptosis in resting B-chronic lymphocytic leukemia (CLL) cells.

Journal: International journal of cancer 20020120

Title: Replacement of N-terminal portions of TGF-alpha with corresponding heregulin sequences affects ligand-induced receptor signaling and intoxication of tumor cells by chimeric growth-factor toxins.

Journal: International journal of cancer 20020120

Title: Coordinated activation of autophosphorylation sites in the RET receptor tyrosine kinase: importance of tyrosine 1062 for GDNF mediated neuronal differentiation and survival.

Journal: The Journal of biological chemistry 20020118

Title: Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors.

Journal: Science (New York, N.Y.) 20020118

Title: Calorimetric and structural studies of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide inhibitors of Src SH2 domain binding.

Journal: Journal of the American Chemical Society 20020116

Title: Meeting at mitosis: cell cycle-specific regulation of c-Src by RPTPalpha.

Journal: Science's STKE : signal transduction knowledge environment 20020115

Title: Inhibition of the Bcr-Abl oncoprotein by Bcr requires phosphoserine 354.

Journal: Cancer research 20020115

Title: Tyrosine phosphorylation mapping of the epidermal growth factor receptor signaling pathway.

Journal: The Journal of biological chemistry 20020111

Title: Light-dependent association of Src with photoreceptor rod outer segment membrane proteins in vivo.

Journal: The Journal of biological chemistry 20020111

Title: Temperature dependence of the epidermal growth factor receptor signaling network can be accounted for by a kinetic model.

Journal: Biochemistry 20020108

Title: 19F NMR studies of vaccinia type IB topoisomerase. Conformational dynamics of the bound DNA substrate.

Journal: The Journal of biological chemistry 20020104

Title: Discrimination between phosphotyrosine-mediated signaling properties of conventional and neuronal Shc adapter molecules.

Journal: Oncogene 20020103

Title: Paxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase.

Journal: Oncogene 20020103

Title: Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d.

Journal: Nature immunology 20020101

Title: Isolation and characterization of a protein-tyrosine kinase and a phosphotyrosine-protein phosphatase from Klebsiella pneumoniae.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020101

Title: Effect of autophosphorylation on the catalytic and regulatory properties of protein tyrosine kinase Src.

Journal: Archives of biochemistry and biophysics 20020101

Title: Dockers at the crossroads.

Journal: Cellular signalling 20020101

Title: Biology of the gonadotropin-releasing hormone system in gynecological cancers.

Journal: European journal of endocrinology 20020101

Title: Fyn tyrosine kinase in Sertoli cells is involved in mouse spermatogenesis.

Journal: Biology of reproduction 20020101

Title: CD5-negative regulation of B cell receptor signaling pathways originates from tyrosine residue Y429 outside an immunoreceptor tyrosine-based inhibitory motif.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020101

Title: Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020101

Title: Platelet endothelial cell adhesion molecule-1 signaling inhibits the activation of human platelets.

Journal: Blood 20020101

Title: Human T-cell leukemia virus type 2 induces survival and proliferation of CD34(+) TF-1 cells through activation of STAT1 and STAT5 by secretion of interferon-gamma and granulocyte macrophage-colony-stimulating factor.

Journal: Blood 20020101

Title: Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-beta peptide exposure: involvement of Src family protein kinases.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020101

Title: A XerD recombinase with unusual active site motifs in Streptococcus pneumoniae.

Journal: Journal of molecular microbiology and biotechnology 20020101

Title: Linkage of rapid estrogen action to MAPK activation by ERalpha-Shc association and Shc pathway activation.

Journal: Molecular endocrinology (Baltimore, Md.) 20020101

Title: Impaired insulin signaling in the liver of transgenic rats with low circulating growth hormone levels.

Journal: The Journal of endocrinology 20020101

Title: Role for adapter proteins in costimulatory signals of CD2 and IL-2 on NK cell activation.

Journal: Molecular immunology 20020101

Title: Evidence for the epidermal growth factor receptor as a target for lung cancer prevention.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020101

Title: MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.

Journal: BMC cell biology 20020101

Title: Characterization of a phosphorylated peptide and peptoid and peptoid-peptide hybrids by mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20020101

Title: Electrophoretic analysis of phosphorylation of the yeast 20S proteasome.

Journal: Electrophoresis 20020101

Title: Kinetics and active site dynamics of Staphylococcus aureus arsenate reductase.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20020101

Title: Delta opioid activation of the mitogen-activated protein kinase cascade does not require transphosphorylation of receptor tyrosine kinases.

Journal: BMC pharmacology 20020101

Title: Activation of human somatostatin receptor 2 promotes apoptosis through a mechanism that is independent from induction of p53.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20020101

Title: Bis(maltolato)oxovanadium(IV) inhibits the activity of PTP1B in Zucker rat skeletal muscle in vivo.

Journal: Molecular and cellular biochemistry 20020101

Title: Endogenous regucalcin suppresses the enhancement of protein phosphatase activity in the cytosol and nucleus of kidney cortex in calcium-administered rats.

Journal: Journal of cellular biochemistry 20020101

Title: Hisactophilin is involved in osmoprotection in Dictyostelium.

Journal: BMC biochemistry 20020101

Title: Glucocorticoids: do we know how they work?

Journal: Arthritis research 20020101

Title: Wheat functional genomics and engineering crop improvement.

Journal: Genome biology 20020101

Title: The role of the Zn(II) binding domain in the mechanism of E. coli DNA topoisomerase I.

Journal: BMC biochemistry 20020101

Title: Evaluation of L-selectin expression and assessment of protein tyrosine phosphorylation in bovine polymorphonuclear neutrophil leukocytes around parturition.

Journal: Veterinary research 20020101

Title: Characterisation and expression of a PP1 serine/threonine protein phosphatase (PfPP1) from the malaria parasite, Plasmodium falciparum: demonstration of its essential role using RNA interference.

Journal: Malaria journal 20020101

Title: Retroviral expression of a kinase-defective IGF-I receptor suppresses growth and causes apoptosis of CHO and U87 cells in-vivo.

Journal: BMC cancer 20020101

Title: Effect of anti-IL-2Ralpha antibody on IL-2-induced Jak/STAT signaling.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20020101

Title: The paradigm of IL-6: from basic science to medicine.

Journal: Arthritis research 20020101

Title: Purification and characterization of protein tyrosine phosphatase PTP-MEG2.

Journal: Journal of cellular biochemistry 20020101

Title: Sam68 associates with the SH3 domains of Grb2 recruiting GAP to the Grb2-SOS complex in insulin receptor signaling.

Journal: Journal of cellular biochemistry 20020101

Title: A p130Cas tyrosine phosphorylated substrate domain decoy disrupts v-crk signaling.

Journal: BMC cell biology 20020101

Title: Ecto-phosphatase activity on the cell surface of Crithidia deanei.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101

Title: MAP kinase phosphatases.

Journal: Genome biology 20020101

Title: Protein phosphatase-2A modulates the serine and tyrosine phosphorylation of paxillin in Lewis lung carcinoma tumor variants.

Journal: Clinical & experimental metastasis 20020101

Title: alpha2-Heremans Schmid glycoprotein, a putative inhibitor of tyrosine kinase, prevents glucose toxicity associated with cardiomyocyte dysfunction.

Journal: Diabetes/metabolism research and reviews 20020101

Title: Alpha2-HS glycoprotein: a protein in search of a function.

Journal: Diabetes/metabolism research and reviews 20020101

Title: Distinct signal transduction processes by IL-4 and IL-13 and influences from the Q551R variant of the human IL-4 receptor alpha chain.

Journal: Respiratory research 20020101

Title: Expression of a releasable form of annexin II by human keratinocytes.

Journal: Journal of cellular biochemistry 20020101

Title: Expression of the Fe65 adapter protein in adult and developing mouse brain.

Journal: Neuroscience 20020101

Title: Molecular recognition by SH2 domains.

Journal: Advances in protein chemistry 20020101

Title: Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes.

Journal: BMC immunology 20020101

Title: Tyrosine phosphorylation of eukaryotic proteins and translocated intimin receptor by enteropathogenic Escherichia coli.

Journal: Methods in enzymology 20020101

Title: Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells.

Journal: BMC biochemistry 20020101

Title: Inhibition of shear-stress-induced platelet aggregation and phosphotyrosine signaling by GPIIb-IIIa antagonists.

Journal: Annals of biomedical engineering 20020101

Title: Cytotoxic activity of a new lipid formulation of doxorubicin in cell lines and primary tumor cells.

Journal: Anticancer research 20020101

Title: Tyrosine phosphorylation in human lymphomas.

Journal: The Histochemical journal 20020101

Title: Abstracts of the Fourth International Symposium on Molecular Insect Science. May 28-June 2, 2002. Tucson, Arizona, USA.

Journal: Journal of insect science (Online) 20020101

Title: Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics.

Journal: Journal of medicinal chemistry 20011220

Title: Design and synthesis of non-peptidic inhibitors for the Syk C-terminal SH2 domain based on structure-based in-silico screening.

Journal: Journal of medicinal chemistry 20011220

Title: Role of tyrosine kinase activity in alpha-adrenergic inhibition of the beta-adrenergically regulated L-type Ca(2+) current in guinea-pig ventricular myocytes.

Journal: The Journal of physiology 20011215

Title: Intracellular distribution of lysosomal sialidase is controlled by the internalization signal in its cytoplasmic tail.

Journal: The Journal of biological chemistry 20011207

Title: The human protein HSPC021 interacts with Int-6 and is associated with eukaryotic translation initiation factor 3.

Journal: The Journal of biological chemistry 20011207

Title: Phosphorylation and structure-based functional studies reveal a positive and a negative role for the activation loop of the c-Abl tyrosine kinase.

Journal: Oncogene 20011206

Title: H(2)O(2)-mediated permeability II: importance of tyrosine phosphatase and kinase activity.

Journal: American journal of physiology. Cell physiology 20011201

Title: Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome.

Journal: Nature genetics 20011201

Title: Regulation of Id2 gene expression by the type 1 IGF receptor and the insulin receptor substrate-1.

Journal: Endocrinology 20011201

Title: Tyrosine phosphorylation-dependent and -independent role of Shc in the regulation of IGF-1-induced mitogenesis and glycogen synthesis.

Journal: Endocrinology 20011201

Title: C-terminal peptide of thrombospondin-1 induces platelet aggregation through the Fc receptor gamma-chain-associated signaling pathway and by agglutination.

Journal: Blood 20011201

Title: The TEL/PDGFbetaR fusion in chronic myelomonocytic leukemia signals through STAT5-dependent and STAT5-independent pathways.

Journal: Blood 20011201

Title: Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart.

Journal: Diabetes 20011201

Title: Insulin signal transduction in skeletal muscle from glucose-intolerant relatives of type 2 diabetic patients [corrected].

Journal: Diabetes 20011201

Title: Activation of JAK2 by the oxidative stress generated with oxidized low-density lipoprotein.

Journal: Free radical biology & medicine 20011201

Title: Nitric oxide increases albumin permeability of isolated rat glomeruli via a phosphorylation-dependent mechanism.

Journal: Journal of the American Society of Nephrology : JASN 20011201

Title: Systemic biochemical effects of inhaled NO in rats: increased expressions of NOS III, nitrotyrosine-, and phosphotyrosine-immunoreactive proteins in liver and kidney tissues.

Journal: Nitric oxide : biology and chemistry 20011201

Title: Role of tyrosine kinases and the tyrosine phosphatase SptP in the interaction of Salmonella with host cells.

Journal: Cellular microbiology 20011201

Title: The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation.

Journal: Structure (London, England : 1993) 20011201

Title: Hierarchy of simulation models in predicting molecular recognition mechanisms from the binding energy landscapes: structural analysis of the peptide complexes with SH2 domains.

Journal: Proteins 20011201

Title: CD28 as a molecular amplifier extending TCR ligation and signaling capabilities.

Journal: Immunity 20011201

Title: Tyrosine kinase activation in breast carcinoma with correlation to HER-2/neu gene amplification and receptor overexpression.

Journal: Human pathology 20011201

Title: Design and application of a cytokine-receptor-based interaction trap.

Journal: Nature cell biology 20011201

Title: [The activation of the phosphotyrosine phosphatase eta is responsible for the somatostatin inhibition of PCCl3 thyroid cell proliferation].

Journal: Minerva endocrinologica 20011201

Title: Alpha-tocopherol modulates tyrosine phosphorylation in human neutrophils by inhibition of protein kinase C activity and activation of tyrosine phosphatases.

Journal: Free radical research 20011201

Title: Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways.

Journal: Molecular medicine (Cambridge, Mass.) 20011201

Title: Basal keratinocytes from uninvolved psoriatic skin exhibit accelerated spreading and focal adhesion kinase responsiveness to fibronectin.

Journal: The Journal of investigative dermatology 20011201

Title: Effects of age on elements of insulin-signaling pathway in central nervous system of rats.

Journal: Endocrine 20011201

Title: Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation.

Journal: The Journal of biological chemistry 20011130

Title: Voltage-independent inhibition of P/Q-type Ca2+ channels in adrenal chromaffin cells via a neuronal Ca2+ sensor-1-dependent pathway involves Src family tyrosine kinase.

Journal: The Journal of biological chemistry 20011130

Title: A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth.

Journal: Cell 20011130

Title: S-Adenosyl-L-homocysteine hydrolase is sequestered into actin rods in Dictyostelium discoideum spores.

Journal: FEBS letters 20011123

Title: Src family kinases mediate receptor-stimulated, phosphoinositide 3-kinase-dependent, tyrosine phosphorylation of dual adaptor for phosphotyrosine and 3-phosphoinositides-1 in endothelial and B cell lines.

Journal: The Journal of biological chemistry 20011116

Title: HSH2: a novel SH2 domain-containing adapter protein involved in tyrosine kinase signaling in hematopoietic cells.

Journal: Biochemical and biophysical research communications 20011116

Title: Multiple stimuli induce tyrosine phosphorylation of the Crk-binding sites of paxillin.

Journal: The Biochemical journal 20011115

Title: C-terminal heparin-binding domain of fibronectin regulates integrin-mediated cell spreading but not the activation of mitogen-activated protein kinase.

Journal: The Biochemical journal 20011115

Title: Association of FcgammaRII with low-density detergent-resistant membranes is important for cross-linking-dependent initiation of the tyrosine phosphorylation pathway and superoxide generation.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20011115

Title: Activation of Syk protein tyrosine kinase through interaction with integrin beta cytoplasmic domains.

Journal: Current biology : CB 20011113

Title: Tyrosine phosphorylation of the catalytic subunit p110 of phosphatidylinositol-3 kinase induced by HMG-CoA reductase inhibitor inhibits its kinase activity in L6 myoblasts.

Journal: FEBS letters 20011109

Title: Insulin receptor substrate-1 pleckstrin homology and phosphotyrosine-binding domains are both involved in plasma membrane targeting.

Journal: The Journal of biological chemistry 20011102

Title: The roles of phosphatidylinositol 3-kinase and protein kinase Czeta for thrombopoietin-induced mitogen-activated protein kinase activation in primary murine megakaryocytes.

Journal: The Journal of biological chemistry 20011102

Title: Modulation of nicotinic acetylcholine receptor turnover by tyrosine phosphorylation in rat myotubes.

Journal: Neuroscience letters 20011102

Title: Signal transduction by VEGF receptor-1 wild type and mutant proteins.

Journal: Cellular signalling 20011101

Title: Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A.

Journal: The Biochemical journal 20011101

Title: SH2 and SH3 domains as targets for anti-proliferative agents.

Journal: Critical reviews in oncology/hematology 20011101

Title: Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells.

Journal: The EMBO journal 20011101

Title: Two mechanisms activate PTPalpha during mitosis.

Journal: The EMBO journal 20011101

Title: The genetics of signal transduction and the outcome of diagnostic tests in growth retardation.

Journal: The Journal of endocrinology 20011101

Title: Chemokine receptor dimerization: two are better than one.

Journal: Trends in immunology 20011101

Title: Enhanced expression of Fc alpha receptor I on blood phagocytes of patients with gram-negative bacteremia is associated with tyrosine phosphorylation of the FcR-gamma subunit.

Journal: Shock (Augusta, Ga.) 20011101

Title: Protein tyrosine phosphatase genes downregulated in melanoma.

Journal: The Journal of investigative dermatology 20011101

Title: Protein kinase C-independent stimulation of activator protein-1 and c-Jun N-terminal kinase activity in human endometrial cancer cells by the LHRH agonist triptorelin.

Journal: European journal of endocrinology 20011101

Title: Phosphorylation of tyrosine 972 of the Helicobacter pylori CagA protein is essential for induction of a scattering phenotype in gastric epithelial cells.

Journal: Molecular microbiology 20011101

Title: Alterations of phospholipase C isozymes in rat cerebral cortex through hyperoxia.

Journal: Biological & pharmaceutical bulletin 20011101

Title: Structure of the type III secretion and substrate-binding domain of Yersinia YopH phosphatase.

Journal: Molecular microbiology 20011101

Title: Role of host phosphotyrosine phosphatase SHP-1 in the development of murine leishmaniasis.

Journal: European journal of immunology 20011101

Title: Topographic changes of focal adhesion components and modulation of p125FAK activation in stretched human periodontal ligament fibroblasts.

Journal: Journal of dental research 20011101

Title: Early cell adhesion events differ between osteoporotic and non-osteoporotic osteoblasts.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20011101

Title: [A variety of functions of conventional and neuronal Shc adapter molecules in phosphotyrosine-mediated signalings].

Journal: Seikagaku. The Journal of Japanese Biochemical Society 20011101

Title: Loss of phosphotyrosine phosphatase activity and changes in the tyrosine phosphorylation state of proteins after storage of sheep platelets in plasma or Seto solution at 4 degrees C.

Journal: Vox sanguinis 20011101

Title: Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid.

Journal: The Journal of biological chemistry 20011026

Title: Regulation of IRS-2 tyrosine phosphorylation in fasting and diabetes.

Journal: Molecular and cellular endocrinology 20011025

Title: Adhesion via CD43 induces Syk activation and cell proliferation in TF-1 cells.

Journal: Biochemical and biophysical research communications 20011019

Title: Phosphorylation of human N-myristoyltransferase by N-myristoylated SRC family tyrosine kinase members.

Journal: Biochemical and biophysical research communications 20011019

Title: Involvement of tyrosine phosphatase PTP1D in the inhibition of interleukin-6-induced Stat3 signaling by alpha-thrombin.

Journal: Biochemical and biophysical research communications 20011019

Title: Integrated src kinase and costimulatory activity enhances signal transduction through single-chain chimeric receptors in T lymphocytes.

Journal: Blood 20011015

Title: The intrinsic ability of AFAP-110 to alter actin filament integrity is linked with its ability to also activate cellular tyrosine kinases.

Journal: Oncogene 20011004

Title: Src directly tyrosine-phosphorylates STAT5 on its activation site and is involved in erythropoietin-induced signaling pathway.

Journal: Oncogene 20011004

Title: Integrin tyrosine phosphorylation in platelet signaling.

Journal: Current opinion in cell biology 20011001

Title: PRL, placental lactogen, and GH induce NA(+)/taurocholate-cotransporting polypeptide gene expression by activating signal transducer and activator of transcription-5 in liver cells.

Journal: Endocrinology 20011001

Title: Hypochlorous acid stimulation of the mitogen-activated protein kinase pathway enhances cell survival.

Journal: Archives of biochemistry and biophysics 20011001

Title: The activation of the phosphotyrosine phosphatase eta (r-PTP eta) is responsible for the somatostatin inhibition of PC Cl3 thyroid cell proliferation.

Journal: Molecular endocrinology (Baltimore, Md.) 20011001

Title: Glial cell-derived neurotrophic factor (GDNF)-induced migration and signal transduction in corneal epithelial cells.

Journal: Investigative ophthalmology & visual science 20011001

Title: Lovastatin-induced cytoskeletal reorganization in lens epithelial cells: role of Rho GTPases.

Journal: Investigative ophthalmology & visual science 20011001

Title: Histological and functional analysis of vascular smooth muscle cells in a novel culture system with honeycomb-like structure.

Journal: Atherosclerosis 20011001

Title: Regulation of epidermal growth factor receptor expression in human melanocytes.

Journal: Experimental dermatology 20011001

Title: Crystal-induced neutrophil activation. VII. Involvement of Syk in the responses to monosodium urate crystals.

Journal: Journal of leukocyte biology 20011001

Title: Integrin-mediated differentiation of a pancreatic carcinoma cell line is independent of FAK or MAPK activation levels.

Journal: Pancreas 20011001

Title: Promegapoietin, a family of chimeric growth factors, supports megakaryocyte development through activation of IL-3 and c-Mpl ligand signaling pathways.

Journal: Experimental hematology 20011001

Title: 14-3-3 proteins; bringing new definitions to scaffolding.

Journal: Oncogene 20011001

Title: Expression of pyrimidine 5'-nucleotidase subclass I during erythrocyte maturation in rats.

Journal: Journal of hematotherapy & stem cell research 20011001

Title: Site-specific incorporation of a phosphotyrosine mimetic reveals a role for tyrosine phosphorylation of SHP-2 in cell signaling.

Journal: Molecular cell 20011001

Title: Molecular basis for the insulinomimetic effects of C-peptide.

Journal: Diabetologia 20011001

Title: SH2-containing inositol phosphatase 2 negatively regulates insulin-induced glycogen synthesis in L6 myotubes.

Journal: Diabetologia 20011001

Title: Differential regulation of T cell receptor-mediated Th1 cell IFN-gamma production and proliferation by divergent cAMP-mediated redox pathways.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20011001

Title: Evidence that increased tyrosine phosphorylation causes disassembly of adherens junctions but does not perturb paracellular permeability in Caco-2 cells.

Journal: Tissue & cell 20011001

Title: EphB/syndecan-2 signaling in dendritic spine morphogenesis.

Journal: Neuron 20010927

Title: G2 phase cell cycle arrest in human skin following UV irradiation.

Journal: Oncogene 20010927

Title: Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation.

Journal: Oncogene 20010927

Title: Enhanced sensitivity of insulin-resistant adipocytes to vanadate is associated with oxidative stress and decreased reduction of vanadate (+5) to vanadyl (+4).

Journal: The Journal of biological chemistry 20010921

Title: Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region.

Journal: Cell 20010921

Title: Tissue-specific regulation of early steps in insulin action in septic rats.

Journal: Life sciences 20010921

Title: Beta-arrestin- and c-Src-dependent degradation of G-protein-coupled receptor kinase 2.

Journal: The EMBO journal 20010917

Title: Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: possible role of Sam68.

Journal: Cellular immunology 20010915

Title: Palmitoylation of caveolin-1 at a single site (Cys-156) controls its coupling to the c-Src tyrosine kinase: targeting of dually acylated molecules (GPI-linked, transmembrane, or cytoplasmic) to caveolae effectively uncouples c-Src and caveolin-1 (TYR-14).

Journal: The Journal of biological chemistry 20010914

Title: The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals.

Journal: Nature 20010913

Title: Phosphorylation-induced activation of tilapia nonspecific cytotoxic cells by serum cytokines.

Journal: Diseases of aquatic organisms 20010912

Title: 14-3-3 protein-activated and autoinhibited forms of plasma membrane H(+)-ATPase.

Journal: Biochemical and biophysical research communications 20010907

Title: Mammary glands reconstituted with Neu/ErbB2 transformed HC11 cells provide a novel orthotopic tumor model for testing anti-cancer agents.

Journal: Oncogene 20010906

Title: A novel phosphotyrosine mimetic 4'-carboxymethyloxy-3'-phosphonophenylalanine (Cpp): exploitation in the design of nonpeptide inhibitors of pp60(Src) SH2 domain.

Journal: Bioorganic & medicinal chemistry letters 20010903

Title: The interaction of dystrophin with beta-dystroglycan is regulated by tyrosine phosphorylation.

Journal: Cellular signalling 20010901

Title: Activation of the transcription factor NF-kappaB by the erythropoietin receptor: structural requirements and biological significance.

Journal: Cellular signalling 20010901

Title: Cell cycling determines integrin-mediated adhesion in osteoblastic ROS 17/2.8 cells exposed to space-related conditions.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010901

Title: Crystal structure of the phosphatidylinositol 3,4-bisphosphate-binding pleckstrin homology (PH) domain of tandem PH-domain-containing protein 1 (TAPP1): molecular basis of lipid specificity.

Journal: The Biochemical journal 20010901

Title: Colony-stimulating factor-1 (CSF-1) receptor-mediated macrophage differentiation in myeloid cells: a role for tyrosine 559-dependent protein phosphatase 2A (PP2A) activity.

Journal: The Biochemical journal 20010901

Title: Direct identification of a major autophosphorylation site on vascular endothelial growth factor receptor Flt-1 that mediates phosphatidylinositol 3'-kinase binding.

Journal: The Biochemical journal 20010901

Title: Tyrosine phosphorylation following alterations in arteriolar intraluminal pressure and wall tension.

Journal: American journal of physiology. Heart and circulatory physiology 20010901

Title: Capacitation is associated with tyrosine phosphorylation and tyrosine kinase-like activity of pig sperm proteins.

Journal: Biology of reproduction 20010901

Title: Cyclic AMP and acidic fibroblast growth factor have opposing effects on tight and adherens junctions in microvascular endothelial cells in vitro.

Journal: Microvascular research 20010901

Title: c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010901

Title: Relaxin signalling links tyrosine phosphorylation to phosphodiesterase and adenylyl cyclase activity.

Journal: Molecular human reproduction 20010901

Title: Inhibition of tyrosine kinase activity induces caspase-dependent apoptosis in anaplastic large cell lymphoma with NPM-ALK (p80) fusion protein.

Journal: Experimental hematology 20010901

Title: Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells.

Journal: Nature cell biology 20010901

Title: Capacitation dependent activation of tyrosine phosphorylation generates two sperm head plasma membrane proteins with high primary binding affinity for the zona pellucida.

Journal: Molecular reproduction and development 20010901

Title: Identifying substrates for endothelium-specific Tie-2 receptor tyrosine kinase from phage-displayed peptide libraries for high throughput screening.

Journal: Combinatorial chemistry & high throughput screening 20010901

Title: Angiotensin II type 2 receptor inhibits epidermal growth factor receptor transactivation by increasing association of SHP-1 tyrosine phosphatase.

Journal: Hypertension (Dallas, Tex. : 1979) 20010901

Title: Parallel assessment of tyrosine phosphorylation and nuclear targeting of proteins.

Journal: BioTechniques 20010901

Title: Kinetic characterization of the changes in protein tyrosine phosphorylation of membranes, cytosolic Ca2+ concentration and viability in boar sperm populations selected by binding to oviductal epithelial cells.

Journal: Reproduction (Cambridge, England) 20010901

Title: Modulation of Rho GTPases and the actin cytoskeleton by Yersinia outer proteins (Yops).

Journal: International journal of medical microbiology : IJMM 20010901

Title: Adenovirus-mediated overexpression and stimulation of the human angiotensin II type 2 receptor in porcine cardiac fibroblasts does not modulate proliferation, collagen I mRNA expression and ERK1/ERK2 activity, but inhibits protein tyrosine phosphatases.

Journal: Journal of molecular medicine (Berlin, Germany) 20010901

Title: 1H, 15N and 13C assignments of the N-terminal domain of Yersinia outer protein H in its apo form and in complex with a phosphotyrosine peptide.

Journal: Journal of biomolecular NMR 20010901

Title: Identification of a tyrosine kinase-phosphorylated protein in arachidonic acid- and prostaglandin A(2)-treated cells in vitro.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20010901

Title: Growth hormone receptor ubiquitination, endocytosis, and degradation are independent of signal transduction via Janus kinase 2.

Journal: The Journal of biological chemistry 20010831

Title: ERK regulates the hepatocyte growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase.

Journal: The Journal of biological chemistry 20010831

Title: Unique regulation of c-Jun N-terminal kinase by PYK2/CAK-beta in angiotensin II-stimulated vascular smooth muscle cells.

Journal: Biochemical and biophysical research communications 20010831

Title: Preserved phosphorylation of RET receptor protein in spinal motor neurons of patients with amyotrophic lateral sclerosis: an immunohistochemical study by a phosphorylation-specific antibody at tyrosine 1062.

Journal: Brain research 20010831

Title: Electrostatic environment surrounding the activation loop phosphotyrosine in the oncoprotein v-Fps.

Journal: Biochemistry 20010828

Title: A repertoire library that allows the selection of synthetic SH2s with altered binding specificities.

Journal: Oncogene 20010823

Title: LAD-1, the Caenorhabditis elegans L1CAM homologue, participates in embryonic and gonadal morphogenesis and is a substrate for fibroblast growth factor receptor pathway-dependent phosphotyrosine-based signaling.

Journal: The Journal of cell biology 20010820

Title: Nitrotyrosine mimics phosphotyrosine binding to the SH2 domain of the src family tyrosine kinase lyn.

Journal: FEBS letters 20010817

Title: Requirement for tyrosine kinase-ERK1/2 signaling in alpha 1 beta 1 integrin-mediated collagen matrix remodeling by rat mesangial cells.

Journal: Experimental cell research 20010815

Title: Growth-inhibitory effect of a streptococcal antitumor glycoprotein on human epidermoid carcinoma A431 cells: involvement of dephosphorylation of epidermal growth factor receptor.

Journal: Cancer research 20010815

Title: Ron-mediated cytoplasmic signaling is dispensable for viability but is required to limit inflammatory responses.

Journal: The Journal of clinical investigation 20010815

Title: Cooperative kinetics of human prostatic acid phosphatase.

Journal: Biochimica et biophysica acta 20010813

Title: Multiple phosphorylation of membrane-associated calcium-dependent protein serine/threonine kinase in Streptomyces fradiae.

Journal: FEMS microbiology letters 20010807

Title: Etk/Bmx tyrosine kinase activates Pak1 and regulates tumorigenicity of breast cancer cells.

Journal: The Journal of biological chemistry 20010803

Title: Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts.

Journal: The Journal of biological chemistry 20010803

Title: Insulin stimulates tyrosine phosphorylation and inactivation of protein-tyrosine phosphatase 1B in vivo.

Journal: The Journal of biological chemistry 20010803

Title: Angiotensin II AT(2) receptors inhibit growth responses in proximal tubule cells.

Journal: American journal of physiology. Renal physiology 20010801

Title: Platelet-derived growth factor stimulates phospholipase C-gamma 1, extracellular signal-regulated kinase, and arachidonic acid release in rat myometrial cells: contribution to cyclic 3',5'-adenosine monophosphate production and effect on cell proliferation.

Journal: Biology of reproduction 20010801

Title: SH2 domain inhibition: a problem solved?

Journal: Current opinion in chemical biology 20010801

Title: Growth hormone induces cellular insulin resistance by uncoupling phosphatidylinositol 3-kinase and its downstream signals in 3T3-L1 adipocytes.

Journal: Diabetes 20010801

Title: Interferon-alpha drives T cell-mediated immunopathology in the intestine.

Journal: European journal of immunology 20010801

Title: Cell adhesion-mediated drug resistance (CAM-DR) protects the K562 chronic myelogenous leukemia cell line from apoptosis induced by BCR/ABL inhibition, cytotoxic drugs, and gamma-irradiation.

Journal: Leukemia 20010801

Title: Erythropoietin and erythropoietin receptors in the peripheral nervous system: changes after nerve injury.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010801

Title: Growth hormone restores glucocorticoid-induced T cell suppression.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010801

Title: Normalization of retinal vascular permeability in experimental diabetes with genistein.

Journal: Investigative ophthalmology & visual science 20010801

Title: Tyrosine phosphorylation of the N-methyl-D-aspartate receptor by exogenous and postsynaptic density-associated Src-family kinases.

Journal: Journal of neurochemistry 20010801

Title: Insulin-independent and wortmannin-resistant targeting of IRS-3 to the plasma membrane via its pleckstrin homology domain mediates a different interaction with the insulin receptor from that of IRS-1.

Journal: Diabetologia 20010801

Title: Abnormal GH receptor signaling in children with idiopathic short stature.

Journal: The Journal of clinical endocrinology and metabolism 20010801

Title: Rottlerin-independent attenuation of pervanadate-induced tyrosine phosphorylation events by protein kinase C-delta in hemopoietic cells.

Journal: Laboratory investigation; a journal of technical methods and pathology 20010801

Title: De novo formation of focal complex-like structures in host cells by invading Streptococci.

Journal: Molecular microbiology 20010801

Title: Induction of tyrosine phosphorylated proteins in THP-1 cells by Salmonella typhimurium, Pasteurella haemolytica and Haemophilus influenzae porins.

Journal: FEMS immunology and medical microbiology 20010801

Title: Effect of increased intracellular melanin concentration on survival of human melanoma cells exposed to different wavelengths of UV radiation.

Journal: International journal of radiation biology 20010801

Title: Utilization of a receptor reserve for effective amplification of mitogenic signaling by an epidermal growth factor mutant deficient in receptor activation.

Journal: Journal of cellular biochemistry 20010801

Title: Podosomes in osteoclast-like cells: structural analysis and cooperative roles of paxillin, proline-rich tyrosine kinase 2 (Pyk2) and integrin alphaVbeta3.

Journal: Journal of cell science 20010801

Title: Altered membrane fluidity and signal transduction in the platelets from patients of thrombotic stroke.

Journal: Molecular and cellular biochemistry 20010801

Title: Integrin activation is required for VEGF and FGF receptor protein presence on human microvascular endothelial cells.

Journal: Molecular and cellular biochemistry 20010801

Title: [The role of beta-catenin in the repair of the damaged airway epithelium in smoking mice].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20010801

Title: Biochemical differences between SUDHL-1 and KARPAS 299 cells derived from t(2;5)-positive anaplastic large cell lymphoma are responsible for the different sensitivity to the antiproliferative effect of p27(Kip1).

Journal: Oncogene 20010727

Title: alpha-Ketocarboxylic acid-based inhibitors of protein tyrosine phosphatases.

Journal: Bioorganic & medicinal chemistry letters 20010723

Title: Role for c-Abl and p73 in the radiation response of male germ cells.

Journal: Oncogene 20010719

Title: The functional interactions between CD98, beta1-integrins, and CD147 in the induction of U937 homotypic aggregation.

Journal: Blood 20010715

Title: Autocatalytic tyrosine-phosphorylation of protein kinase CK2 alpha and alpha' subunits: implication of Tyr182.

Journal: The Biochemical journal 20010715

Title: Differential phosphorylation of paxillin in response to surface-bound serum proteins during early osteoblast adhesion.

Journal: Biochemical and biophysical research communications 20010713

Title: Thy-1 binds to integrin beta(3) on astrocytes and triggers formation of focal contact sites.

Journal: Current biology : CB 20010710

Title: Human leptin signaling in human peripheral blood mononuclear cells: activation of the JAK-STAT pathway.

Journal: Cellular immunology 20010710

Title: Selective insulin-induced activation of class I(A) phosphoinositide 3-kinase in PIKfyve immune complexes from 3T3-L1 adipocytes.

Journal: Molecular and cellular endocrinology 20010705

Title: Alterations of the insulin-like growth factor system in patients with polycythemia vera.

Journal: Molecular and cellular endocrinology 20010705

Title: Calyculin-A induces focal adhesion assembly and tyrosine phosphorylation of p125(Fak), p130(Cas), and paxillin in Swiss 3T3 cells.

Journal: Journal of cellular physiology 20010701

Title: Insulin and IGF-I inhibit calcium-dependent chloride secretion by T84 human colonic epithelial cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010701

Title: Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family.

Journal: Clinical immunology (Orlando, Fla.) 20010701

Title: SHP-1 expression by malignant small B-cell lymphomas reflects the maturation stage of their normal B-cell counterparts.

Journal: The American journal of surgical pathology 20010701

Title: 18 kDa protein tyrosine phosphatase in the ocular lens.

Journal: Experimental eye research 20010701

Title: The integrin, alpha6beta1, is necessary for the matrix-dependent activation of FAK and MAP kinase and the migration of human hepatocarcinoma cells.

Journal: Hepatology (Baltimore, Md.) 20010701

Title: Analysis of tyrosine phosphorylation-dependent protein-protein interactions in TrkB-mediated intracellular signaling using modified yeast two-hybrid system.

Journal: Journal of biochemistry 20010701

Title: PEAZ-1: a new human prostate neoplastic epithelial cell line.

Journal: The Prostate 20010701

Title: Overexpression of HER-2/neu enhances the sensitivity of human bladder cancer cells to urinary isoflavones.

Journal: European journal of cancer (Oxford, England : 1990) 20010701

Title: The adaptor protein shc is involved in the negative regulation of NK cell-mediated cytotoxicity.

Journal: European journal of immunology 20010701

Title: Association of SLP-65/BLNK with the B cell antigen receptor through a non-ITAM tyrosine of Ig-alpha.

Journal: European journal of immunology 20010701

Title: IFN-alpha and IL-18 synergistically enhance IFN-gamma production in human NK cells: differential regulation of Stat4 activation and IFN-gamma gene expression by IFN-alpha and IL-12.

Journal: European journal of immunology 20010701

Title: Quadrupole time-of-flight versus triple-quadrupole mass spectrometry for the determination of phosphopeptides by precursor ion scanning.

Journal: Journal of mass spectrometry : JMS 20010701

Title: Labile sulfogroup allows differentiation of sulfotyrosine and phosphotyrosine in peptides.

Journal: Journal of mass spectrometry : JMS 20010701

Title: Cross talk of the interferon-alpha/beta signalling complex with gp130 for effective interleukin-6 signalling.

Journal: Genes to cells : devoted to molecular & cellular mechanisms 20010701

Title: Membrane-targeting is critical for the phosphorylation of Vav2 by activated EGF receptor.

Journal: Cellular signalling 20010701

Title: Src family kinase involvement in muscarinic receptor-induced tyrosine phosphorylation in differentiated SH-SY5Y cells.

Journal: Neurochemical research 20010701

Title: Phosphotyrosines 627 and 659 of Gab1 constitute a bisphosphoryl tyrosine-based activation motif (BTAM) conferring binding and activation of SHP2.

Journal: The Journal of biological chemistry 20010629

Title: Inhibition of the catalytic activity of cell adhesion kinase beta by protein-tyrosine phosphatase-PEST-mediated dephosphorylation.

Journal: The Journal of biological chemistry 20010629

Title: Crystal structure of a complex of a type IA DNA topoisomerase with a single-stranded DNA molecule.

Journal: Nature 20010628

Title: Heregulin-dependent translocation and hyperphosphorylation of ErbB-2.

Journal: Oncogene 20010628

Title: Effect of H-7 on cultured human trabecular meshwork cells.

Journal: Molecular vision 20010627

Title: Suppressor of cytokine signaling 1 interacts with the macrophage colony-stimulating factor receptor and negatively regulates its proliferation signal.

Journal: The Journal of biological chemistry 20010622

Title: Genomic organization of the Shc-related phosphotyrosine adapters and characterization of the full-length Sck/ShcB: specific association of p68-Sck/ShcB with pp135.

Journal: Biochemical and biophysical research communications 20010622

Title: Soluble E-selectin induces monocyte chemotaxis through Src family tyrosine kinases.

Journal: The Journal of biological chemistry 20010615

Title: Regulation of the Src homology 2-containing inositol 5-phosphatase SHIP1 in HIP1/PDGFbeta R-transformed cells.

Journal: The Journal of biological chemistry 20010615

Title: Aggretin, a heterodimeric C-type lectin from Calloselasma rhodostoma (Malayan pit viper), stimulates platelets by binding to α2β1 integrin and glycoprotein Ib, activating Syk and phospholipase Cγ 2, but does not involve the glycoprotein VI/Fc receptor γ chain collagen receptor.

Journal: The Journal of biological chemistry 20010615

Title: Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade.

Journal: The Journal of biological chemistry 20010615

Title: Tyrosine kinase activation by the angiotensin II receptor in the absence of calcium signaling.

Journal: The Journal of biological chemistry 20010615

Title: Stat6 is necessary and sufficient for IL-4's role in Th2 differentiation and cell expansion.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010615

Title: Inhibitors to the Src SH2 domain: a lesson in structure--thermodynamic correlation in drug design.

Journal: Archives of biochemistry and biophysics 20010615

Title: Activation of sickle red blood cell adhesion via integrin-associated protein/CD47-induced signal transduction.

Journal: The Journal of clinical investigation 20010615

Title: Differential regulation of cell migration and cell cycle progression by FAK complexes with Src, PI3K, Grb7 and Grb2 in focal contacts.

Journal: FEBS letters 20010615

Title: Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition.

Journal: Cell 20010615

Title: Y-27632, an inhibitor of Rho-associated kinases, prevents tyrosine phosphorylation of focal adhesion kinase and paxillin induced by bombesin: dissociation from tyrosine phosphorylation of p130(CAS).

Journal: Experimental cell research 20010610

Title: IgE receptor type I-dependent tyrosine phosphorylation of phospholipid scramblase.

Journal: The Journal of biological chemistry 20010608

Title: Astrocyte differentiation of fetal neuroepithelial cells involving cardiotrophin-1-induced activation of STAT3.

Journal: Cytokine 20010607

Title: Tyrosine-phosphorylated low density lipoprotein receptor-related protein 1 (Lrp1) associates with the adaptor protein SHC in SRC-transformed cells.

Journal: The Journal of biological chemistry 20010601

Title: Antiproliferative signaling of luteinizing hormone-releasing hormone in human endometrial and ovarian cancer cells through G protein alpha(I)-mediated activation of phosphotyrosine phosphatase.

Journal: Endocrinology 20010601

Title: Stimulation by n6-cyclopentyladenosine of A1 adenosine receptors, coupled to galphai2 protein subunit, has a capacitative effect on human spermatozoa.

Journal: Biology of reproduction 20010601

Title: Janus kinase 2 is involved in stromal cell-derived factor-1alpha-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells.

Journal: Blood 20010601

Title: A use-dependent tyrosine dephosphorylation of NMDA receptors is independent of ion flux.

Journal: Nature neuroscience 20010601

Title: TSH-induced differentiated functions correlate with enhancement of phosphotyrosine phosphatase activity in thyroid cells. Effect of phorbol 12-myristate 13-acetate.

Journal: The Journal of endocrinology 20010601

Title: Subcellular localization of insulin receptor substrate family proteins associated with phosphatidylinositol 3-kinase activity and alterations in lipolysis in primary mouse adipocytes from IRS-1 null mice.

Journal: Diabetes 20010601

Title: Characterization of a novel serine/threonine protein phosphatase (PfPPJ) from the malaria parasite, Plasmodium falciparum.

Journal: Molecular and biochemical parasitology 20010601

Title: STAT3 is constitutively active in some patients with Polycythemia rubra vera.

Journal: Experimental hematology 20010601

Title: Peroxisomal deficiencies are associated with altered activity of endothelial NOS in human fibroblasts.

Journal: Nitric oxide : biology and chemistry 20010601

Title: The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway.

Journal: The EMBO journal 20010601

Title: Detergent-resistant membrane domains are required for mast cell activation but dispensable for tyrosine phosphorylation upon aggregation of the high affinity receptor for IgE.

Journal: Journal of biochemistry 20010601

Title: Energetic determinants of tyrosine phosphorylation of focal adhesion proteins during hypoxia/reoxygenation of kidney proximal tubules.

Journal: The American journal of pathology 20010601

Title: Functional preference of the constituent amino acid residues in a phage-library-based nonphosphorylated inhibitor of the Grb2-SH2 domain.

Journal: The journal of peptide research : official journal of the American Peptide Society 20010601

Title: Fingerprinting of signal transduction pathways using a combination of anti-phosphotyrosine immunoprecipitations and two-dimensional polyacrylamide gel electrophoresis.

Journal: Electrophoresis 20010601

Title: Detection of tyrosine phosphorylated proteins in Trichinella spiralis L1 larvae.

Journal: Parasite (Paris, France) 20010601

Title: c-Cbl ubiquitinates the EGF receptor at the plasma membrane and remains receptor associated throughout the endocytic route.

Journal: Journal of cell science 20010601

Title: SHP-2 complex formation with the SHP-2 substrate-1 during C2C12 myogenesis.

Journal: Journal of cell science 20010601

Title: pp60(c-src) and related tyrosine kinases: a role in the assembly and reorganization of matrix adhesions.

Journal: Journal of cell science 20010601

Title: Inhibitory effect of regucalcin on protein phosphatase activity in the nuclei of rat kidney cortex.

Journal: Journal of cellular biochemistry 20010601

Title: Pulling strings below the surface: hormone receptor signaling through inhibition of protein tyrosine phosphatases.

Journal: Endocrine 20010601

Title: Phosphotyrosine profiling to identify novel components of interferon and interleukin 6-family cytokine signalling.

Journal: Proteomics 20010601

Title: Tamoxifen interacts with NEU/C-ERBB-2 receptor and inhibits growth of human malignant glioma cell lines.

Journal: The Kobe journal of medical sciences 20010601

Title: Leptin stimulates rat aortic smooth muscle cell proliferation and migration.

Journal: The Kobe journal of medical sciences 20010601

Title: Pertussis toxin activates tyrosine kinase signaling cascade in myelomonocytic cells: a mechanism for cell adhesion.

Journal: Biochemical and biophysical research communications 20010525

Title: Phospho-Azatyrosine, a less effective protein-tyrosine phosphatase substrate than phosphotyrosine.

Journal: Bioorganic & medicinal chemistry letters 20010521

Title: The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases.

Journal: The Journal of biological chemistry 20010518

Title: p110beta and p110delta phosphatidylinositol 3-kinases up-regulate Fc(epsilon)RI-activated Ca2+ influx by enhancing inositol 1,4,5-trisphosphate production.

Journal: The Journal of biological chemistry 20010518

Title: Functional uncoupling of T-cell receptor engagement and Lck activation in anergic human thymic CD4+ T cells.

Journal: The Journal of biological chemistry 20010518

Title: Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein.

Journal: Science (New York, N.Y.) 20010518

Title: HC fragment (C-terminal portion of the heavy chain) of tetanus toxin activates protein kinase C isoforms and phosphoproteins involved in signal transduction.

Journal: The Biochemical journal 20010515

Title: Caveolin-1 and a 29-kDa caveolin-associated protein are phosphorylated on tyrosine in cells expressing a temperature-sensitive v-Abl kinase.

Journal: Experimental cell research 20010515

Title: Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1B and augment insulin action.

Journal: Biochemistry 20010515

Title: Phosphoinositide 3-kinase modulation of beta(3)-integrin represents an endogenous 'braking' mechanism during neutrophil transmatrix migration.

Journal: Blood 20010515

Title: Role of p190RhoGAP in beta 2 integrin regulation of RhoA in human neutrophils.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010515

Title: c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation.

Journal: The Journal of biological chemistry 20010511

Title: Identification of reelin-induced sites of tyrosyl phosphorylation on disabled 1.

Journal: The Journal of biological chemistry 20010511

Title: The ERBB2/HER2 receptor differentially interacts with ERBIN and PICK1 PSD-95/DLG/ZO-1 domain proteins.

Journal: The Journal of biological chemistry 20010504

Title: Mac-1-dependent tyrosine phosphorylation during neutrophil adhesion.

Journal: American journal of physiology. Cell physiology 20010501

Title: TNF-alpha inhibits flow and insulin signaling leading to NO production in aortic endothelial cells.

Journal: American journal of physiology. Cell physiology 20010501

Title: Protein tyrosine phosphorylation in sperm during gamete interaction in the mouse: the influence of glucose.

Journal: Biology of reproduction 20010501

Title: Impact of epididymal maturation on the tyrosine phosphorylation patterns exhibited by rat spermatozoa.

Journal: Biology of reproduction 20010501

Title: Pioglitazone ameliorates tumor necrosis factor-alpha-induced insulin resistance by a mechanism independent of adipogenic activity of peroxisome proliferator--activated receptor-gamma.

Journal: Diabetes 20010501

Title: Insulin and leptin acutely regulate cholesterol ester metabolism in macrophages by novel signaling pathways.

Journal: Diabetes 20010501

Title: Gene dosage-dependent functions for phosphotyrosine-Grb2 signaling during mammalian tissue morphogenesis.

Journal: Current biology : CB 20010501

Title: Protein phosphorylation in mitochondria from human placenta.

Journal: Placenta 20010501

Title: Vanadium(V) complexes in enzyme systems: aqueous chemistry, inhibition and molecular modeling in inhibitor design.

Journal: Journal of inorganic biochemistry 20010501

Title: Phosphorylation of LHI beta during membrane synthesis in the photosynthetic bacterium Rhodovulum sulfidophilum.

Journal: Current microbiology 20010501

Title: Histamine deficiency suppresses murine haptoglobin production and modifies hepatic protein tyrosine phosphorylation.

Journal: Cellular and molecular life sciences : CMLS 20010501

Title: FcgammaRIIA exogenously expressed in HeLa cells activates the mitogen-activated protein kinase cascade by a mechanism dependent on the endogenous expression of the protein tyrosine kinase Syk.

Journal: European journal of immunology 20010501

Title: Focal adhesion kinase regulates beta1 integrin-dependent T cell migration through an HEF1 effector pathway.

Journal: European journal of immunology 20010501

Title: Toxoplasma gondii down-regulates MHC class II gene expression and antigen presentation by murine macrophages via interference with nuclear translocation of STAT1alpha.

Journal: European journal of immunology 20010501

Title: The protein tyrosine kinase syk activity is reduced by clustering the mast cell function-associated antigen.

Journal: European journal of immunology 20010501

Title: Phosphorylation and activation of protein tyrosine phosphatase (PTP) 1B by insulin receptor.

Journal: Molecular and cellular biochemistry 20010501

Title: Phosphoamino acid analysis.

Journal: Current protocols in cell biology 20010501

Title: Phosphoamino acid analysis.

Journal: Current protocols in molecular biology 20010501

Title: Analysis of phosphorylation of unlabeled proteins.

Journal: Current protocols in molecular biology 20010501

Title: Detection of phosphorylation by enzymatic techniques.

Journal: Current protocols in molecular biology 20010501

Title: Production of antibodies that recognize specific tyrosine-phosphorylated peptides.

Journal: Current protocols in molecular biology 20010501

Title: Phosphoamino acid analysis.

Journal: Current protocols in protein science 20010501

Title: Detection of phosphorylation by immunological techniques.

Journal: Current protocols in protein science 20010501

Title: Antiphosphotyrosine blotting.

Journal: Current protocols in immunology 20010501

Title: The Src kinase p56(lck) up-regulates VLA-4 integrin affinity. Implications for rapid spontaneous and chemokine-triggered T cell adhesion to VCAM-1 and fibronectin.

Journal: The Journal of biological chemistry 20010427

Title: Agrin-induced activation of acetylcholine receptor-bound Src family kinases requires Rapsyn and correlates with acetylcholine receptor clustering.

Journal: The Journal of biological chemistry 20010427

Title: A yeast two-hybrid study of human p97/Gab2 interactions with its SH2 domain-containing binding partners.

Journal: FEBS letters 20010427

Title: Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20010424

Title: Ultraviolet radiation inhibits interleukin-2-induced tyrosine phosphorylation and the activation of STAT5 in T lymphocytes.

Journal: The Journal of biological chemistry 20010420

Title: Multiple effector domains within SNT1 coordinate ERK activation and neuronal differentiation of PC12 cells.

Journal: The Journal of biological chemistry 20010420

Title: Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland.

Journal: The Journal of biological chemistry 20010420

Title: c-Src tyrosine kinase binds the beta 2-adrenergic receptor via phospho-Tyr-350, phosphorylates G-protein-linked receptor kinase 2, and mediates agonist-induced receptor desensitization.

Journal: The Journal of biological chemistry 20010420

Title: Regulation of type II phosphatidylinositol phosphate kinase by tyrosine phosphorylation in bovine rod outer segments.

Journal: Biochemistry 20010417

Title: A common epitope is shared by activated signal transducer and activator of transcription-5 (STAT5) and the phosphorylated erythropoietin receptor: implications for the docking model of STAT activation.

Journal: Blood 20010415

Title: Molecular regulation of tumor cell vasculogenic mimicry by tyrosine phosphorylation: role of epithelial cell kinase (Eck/EphA2).

Journal: Cancer research 20010415

Title: Carbachol stimulates TYR phosphorylation and association of PKCdelta and PYK2 in pancreas.

Journal: Biochemical and biophysical research communications 20010413

Title: Electroconvulsive shock increases the phosphorylation of Pyk2 in the rat hippocampus.

Journal: Biochemical and biophysical research communications 20010413

Title: The SH2 domain containing inositol 5-phosphatase SHIP2 controls phosphatidylinositol 3,4,5-trisphosphate levels in CHO-IR cells stimulated by insulin.

Journal: Biochemical and biophysical research communications 20010406

Title: BCR gene expression blocks Bcr-Abl induced pathogenicity in a mouse model.

Journal: Oncogene 20010405

Title: Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts.

Journal: Journal of cellular physiology 20010401

Title: TNF-alpha induces protein synthesis through PI3-kinase-Akt/PKB pathway in cardiac myocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20010401

Title: The Bcr N-terminal oligomerization domain contributes to the full oncogenicity of P190 Bcr/Abl in transgenic mice.

Journal: International journal of molecular medicine 20010401

Title: Detection of insulin receptor tyrosine kinase activity using time-resolved fluorescence energy transfer technology.

Journal: Analytical biochemistry 20010401

Title: Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632.

Journal: Investigative ophthalmology & visual science 20010401

Title: The role of phosphoinositide 3-kinase in spreading osteoclasts induced by colony-stimulating factor-1.

Journal: European journal of endocrinology 20010401

Title: Tyrosine phosphorylation of insulin receptor substrate-1 (IRS-1) by oxidant stress in cerebellar granule neurons: modulation by N-methyl-D-aspartate through calcineurin activity.

Journal: Journal of neurochemistry 20010401

Title: The clustered Fcgamma receptor II is recruited to Lyn-containing membrane domains and undergoes phosphorylation in a cholesterol-dependent manner.

Journal: European journal of immunology 20010401

Title: Residues Y429 and Y463 of the human CD5 are targeted by protein tyrosine kinases.

Journal: European journal of immunology 20010401

Title: Protein kinase C delta regulates neural cell adhesion molecule polysialylation state in the rat brain.

Journal: Journal of neurochemistry 20010401

Title: Identification of mouse NMDA receptor subunit NR2A C-terminal tyrosine sites phosphorylated by coexpression with v-Src.

Journal: Journal of neurochemistry 20010401

Title: Bivalent binding and signaling characteristics of Leridistim, a novel chimeric dual agonist of interleukin-3 and granulocyte colony-stimulating factor receptors.

Journal: Experimental hematology 20010401

Title: Detection of tyrosine phosphorylated peptides by precursor ion scanning quadrupole TOF mass spectrometry in positive ion mode.

Journal: Analytical chemistry 20010401

Title: Fc-receptor dependent platelet aggregation induced by monoclonal antibodies against platelet glycoprotein Ib or von Willebrand factor.

Journal: Thrombosis and haemostasis 20010401

Title: Structural and functional hot spots in cytokine receptors.

Journal: International journal of hematology 20010401

Title: Insulin-like effect of zinc in mytilus digestive gland cells: modulation of tyrosine kinase-mediated cell signaling.

Journal: General and comparative endocrinology 20010401

Title: Engagement of endogenous ganglioside GM1a induces tyrosine phosphorylation involved in neuron-like differentiation of PC12 cells.

Journal: Glycobiology 20010401

Title: The genetics of signal transduction and the effect of smoking on intrauterine growth.

Journal: International journal of epidemiology 20010401

Title: Phosphorylation of prolidase increases the enzyme activity.

Journal: Molecular and cellular biochemistry 20010401

Title: Natural resistance to intracellular pathogens: modulation of macrophage signal transduction related to the expression of the Bcg locus.

Journal: Proteomics 20010401

Title: A novel adapter protein employs a phosphotyrosine binding domain and exceptionally basic N-terminal domains to capture and localize an atypical protein kinase C: characterization of Caenorhabditis elegans C kinase adapter 1, a protein that avidly binds protein kinase C3.

Journal: The Journal of biological chemistry 20010330

Title: Structural properties and mechanisms that govern association of C kinase adapter 1 with protein kinase C3 and the cell periphery.

Journal: The Journal of biological chemistry 20010330

Title: Activation of mitogen-activated protein kinases p42/44, p38, and stress-activated protein kinases in myelo-monocytic cells by Treponema lipoteichoic acid.

Journal: The Journal of biological chemistry 20010330

Title: The BPS domain of Grb10 inhibits the catalytic activity of the insulin and IGF1 receptors.

Journal: FEBS letters 20010330

Title: Suppression of apoptosis induced by growth factor withdrawal by an oncogenic form of c-Cbl.

Journal: The Journal of biological chemistry 20010323

Title: Comparative study of protein tyrosine phosphatase-epsilon isoforms: membrane localization confers specificity in cellular signalling.

Journal: The Biochemical journal 20010315

Title: Expression and purification of human recombinant GST-FGF receptor-1.

Journal: Journal of biotechnology 20010309

Title: Western blotting as a method for studying cell-biomaterial interactions: the role of protein collection.

Journal: Journal of biomedical materials research 20010305

Title: 17-beta estradiol elicits an autocrine leiomyoma cell proliferation: evidence for a stimulation of protein kinase-dependent pathway.

Journal: Journal of cellular physiology 20010301

Title: Microglia, astrocytes, and macrophages react differentially to central and peripheral lesions in the developing and mature rat whisker-to-barrel pathway: a study using immunohistochemistry for lipocortin1, phosphotyrosine, s100 beta, and mannose receptors.

Journal: Experimental neurology 20010301

Title: Impaired PI 3-kinase activation in adipocytes from early growth-restricted male rats.

Journal: American journal of physiology. Endocrinology and metabolism 20010301

Title: Activation of the EBV/C3d receptor (CR2, CD21) on human B lymphocyte surface triggers tyrosine phosphorylation of the 95-kDa nucleolin and its interaction with phosphatidylinositol 3 kinase.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010301

Title: Functional association of CD9 with the Fc gamma receptors in macrophages.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010301

Title: Tyrosine phosphorylation-dependent activation of NF-kappa B. Requirement for p56 LCK and ZAP-70 protein tyrosine kinases.

Journal: European journal of biochemistry 20010301

Title: Signal transduction activated by the cancer chemopreventive isothiocyanates: cleavage of BID protein, tyrosine phosphorylation and activation of JNK.

Journal: British journal of cancer 20010301

Title: Altered autophosphorylation of the insulin receptor in the ovary of a woman with polycystic ovary syndrome.

Journal: Fertility and sterility 20010301

Title: Insulin resistance with enhanced insulin signaling in high-salt diet-fed rats.

Journal: Diabetes 20010301

Title: Multisite phosphotyping of the ErbB-2 oncoprotein in human breast cancer.

Journal: Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology 20010301

Title: X-Ray structure of citrate bound to Src SH2 leads to a high-affinity, bone-targeted Src SH2 inhibitor.

Journal: Journal of medicinal chemistry 20010301

Title: Carboxyl terminal sequence of human phospholipase Cgamma2.

Journal: Platelets 20010301

Title: Capacitation-associated changes in protein tyrosine phosphorylation, hyperactivation and acrosome reaction in hamster spermatozoa.

Journal: Andrologia 20010301

Title: Increased expression of iNOS and c-fos via regulation of protein tyrosine phosphorylation and MEK1/ERK2 proteins in terminal bronchiole lesions in the lungs of rats exposed to cigarette smoke.

Journal: Archives of toxicology 20010301

Title: Analysis of in vitro interactions of protein tyrosine phosphatase 1B with insulin receptors.

Journal: Molecular and cellular endocrinology 20010227

Title: Interleukin-4 induces two distinct GAS-binding complexes containing STAT6: evidence for DNA binding of STAT6 monomer.

Journal: Molecules and cells 20010227

Title: Dexamethasone modulates TCR zeta chain expression and antigen receptor-mediated early signaling events in human T lymphocytes.

Journal: Cellular immunology 20010225

Title: TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-alpha/beta dimers.

Journal: Science (New York, N.Y.) 20010223

Title: G(i)-mediated Cas tyrosine phosphorylation in vascular endothelial cells stimulated with sphingosine 1-phosphate: possible involvement in cell motility enhancement in cooperation with Rho-mediated pathways.

Journal: The Journal of biological chemistry 20010216

Title: The adapter type protein CMS/CD2AP binds to the proto-oncogenic protein c-Cbl through a tyrosine phosphorylation-regulated Src homology 3 domain interaction.

Journal: The Journal of biological chemistry 20010216

Title: Identification of residues in the N-terminal domain of the Yersinia tyrosine phosphatase that are critical for substrate recognition.

Journal: The Journal of biological chemistry 20010216

Title: Phosphatidic acid regulates tyrosine phosphorylating activity in human neutrophils: enhancement of Fgr activity.

Journal: The Journal of biological chemistry 20010216

Title: Mitogen-activated protein kinase p38 mediates regulation of chondrocyte differentiation by parathyroid hormone.

Journal: The Journal of biological chemistry 20010216

Title: Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development.

Journal: Blood 20010215

Title: Comparison of a T cell clone and of T cells from a TCR transgenic mouse: TCR transgenic T cells specific for self-antigen are atypical.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010215

Title: A model of activation of the protein tyrosine phosphatase SHP-2 by the human leptin receptor.

Journal: Biochimica et biophysica acta 20010209

Title: Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages.

Journal: Current biology : CB 20010206

Title: Src homology 2-containing inositol 5-phosphatase 1 binds to the multifunctional docking site of c-Met and potentiates hepatocyte growth factor-induced branching tubulogenesis.

Journal: The Journal of biological chemistry 20010202

Title: Simultaneous induction of galectin-3 phosphorylated on tyrosine residue, p21(WAF1/Cip1/Sdi1), and the proliferating cell nuclear antigen at a distinctive period of repair of hepatocytes injured by CCl4.

Journal: Biochemical and biophysical research communications 20010202

Title: Effects of phosphotyrosine phosphatase inhibition on insulin secretion and intracellular signaling events in rat pancreatic islets.

Journal: Biochemical and biophysical research communications 20010202

Title: SHP2 and cbl participate in alpha-chemokine receptor CXCR4-mediated signaling pathways.

Journal: Blood 20010201

Title: Determination of the tyrosine phosphorylation sites in the T cell transmembrane glycoprotein CD5.

Journal: International immunology 20010201

Title: Distinct functions of the two protein tyrosine phosphatase domains of LAR (leukocyte common antigen-related) on tyrosine dephosphorylation of insulin receptor.

Journal: Molecular endocrinology (Baltimore, Md.) 20010201

Title: Specificity of natural and artificial substrates for human Cdc25A.

Journal: Analytical biochemistry 20010201

Title: Amino-terminal modification and tyrosine phosphorylation of [corrected] carboxy-terminal fragments of the amyloid precursor protein in Alzheimer's disease and Down's syndrome brain.

Journal: Neurobiology of disease 20010201

Title: Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling.

Journal: The Biochemical journal 20010201

Title: Nerve growth factor inhibits PC12 cell PDE 2 phosphodiesterase activity and increases PDE 2 binding to phosphoproteins.

Journal: Journal of neurochemistry 20010201

Title: Insulin signal transduction in rat small intestine: role of MAP kinases in expression of mucosal hydrolases.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010201

Title: Regulation of MAP kinase by calcium-sensing receptor in bovine parathyroid and CaR-transfected HEK293 cells.

Journal: American journal of physiology. Renal physiology 20010201

Title: Vanadate ingestion increases the gain in wound breaking strength and leads to better organized collagen fibers in rats during healing.

Journal: Plastic and reconstructive surgery 20010201

Title: Signal transduction pathways through TRK-A and TRK-B receptors in human neuroblastoma cells.

Journal: Japanese journal of cancer research : Gann 20010201

Title: Long-term denervation impairs insulin receptor substrate-1-mediated insulin signaling in skeletal muscle.

Journal: Metabolism: clinical and experimental 20010201

Title: Expression of the small tyrosine phosphatase (Stp1) in Saccharomyces cerevisiae: a study on protein tyrosine phosphorylation.

Journal: Electrophoresis 20010201

Title: The 'early' CD4+CD8+ stage of thymocte differentiation hallmarks the end of a strong positive correlation between extracellular matrix receptor expression and protein tyrosine phosphorylation.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20010201

Title: Growth hormone induces tyrosyl phosphorylation of the transcription factors Stat5a and Stat5b in CMT-U335 canine mammary tumor cells.

Journal: Domestic animal endocrinology 20010201

Title: [Effects of ischemia/reperfusion on the phosphotyrosine proteins contents in hippocampus].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20010201

Title: Domain-dependent function of the rasGAP-binding protein p62Dok in cell signaling.

Journal: The Journal of biological chemistry 20010126

Title: Phosphorylation of Wzc, a tyrosine autokinase, is essential for assembly of group 1 capsular polysaccharides in Escherichia coli.

Journal: The Journal of biological chemistry 20010126

Title: Characterization of a prostate-specific tyrosine phosphatase by mutagenesis and expression in human prostate cancer cells.

Journal: The Journal of biological chemistry 20010126

Title: Coupling of heterotrimeric Gi proteins to the erythropoietin receptor.

Journal: The Journal of biological chemistry 20010119

Title: Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression.

Journal: The EMBO journal 20010115

Title: Rhodocytin induces platelet aggregation by interacting with glycoprotein Ia/IIa (GPIa/IIa, Integrin alpha 2beta 1). Involvement of GPIa/IIa-associated src and protein tyrosine phosphorylation.

Journal: The Journal of biological chemistry 20010112

Title: Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes.

Journal: The Journal of biological chemistry 20010112

Title: Intramolecular interactions in protein tyrosine phosphatase RPTPmu: kinetic evidence.

Journal: Biochemical and biophysical research communications 20010112

Title: Characterization of Fyn-mediated tyrosine phosphorylation sites on GluR epsilon 2 (NR2B) subunit of the N-methyl-D-aspartate receptor.

Journal: The Journal of biological chemistry 20010105

Title: The addition of bisecting N-acetylglucosamine residues to E-cadherin down-regulates the tyrosine phosphorylation of beta-catenin.

Journal: The Journal of biological chemistry 20010105

Title: Evidence for two distinct epitopes within collagen for activation of murine platelets.

Journal: The Journal of biological chemistry 20010105

Title: Cloning protein tyrosine kinases by screening cDNA libraries with antiphosphotyrosine antibodies.

Journal: Methods in molecular biology (Clifton, N.J.) 20010101

Title: Immunoprecipitation and western blotting of phosphotyrosine-containing proteins.

Journal: Methods in molecular biology (Clifton, N.J.) 20010101

Title: JAK-mediated phosphorylation and activation of STAT signaling proteins. Analysis by phosphotyrosine blotting and EMSA.

Journal: Methods in molecular biology (Clifton, N.J.) 20010101

Title: Detection of phosphorylation-dependent interactions by far-western gel overlay.

Journal: Methods in molecular biology (Clifton, N.J.) 20010101

Title: Purification of tyrosine-phosphorylated proteins by immunoaffinity chromatography and direct cloning of their cDNAs from bacterial expression libraries.

Journal: Methods in molecular biology (Clifton, N.J.) 20010101

Title: Analysis of SH2 domain--phosphopeptide interactions by isothermal titration calorimetry and surface plasmon resonance.

Journal: Methods in molecular biology (Clifton, N.J.) 20010101

Title: VCAM-1 activates phosphatidylinositol 3-kinase and induces p120Cbl phosphorylation in human airway smooth muscle cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010101

Title: Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010101

Title: Listeria monocytogenes modulates macrophage cytokine responses through STAT serine phosphorylation and the induction of suppressor of cytokine signaling 3.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010101

Title: Distinct T cell developmental consequences in humans and mice expressing identical mutations in the DLAARN motif of ZAP-70.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010101

Title: Rat seminiferous epithelium contains a unique junction (Ectoplasmic specialization) with signaling properties both of cell/cell and cell/matrix junctions.

Journal: Biology of reproduction 20010101

Title: The src homology 2 domain of Bcr/Abl is required for efficient induction of chronic myeloid leukemia-like disease in mice but not for lymphoid leukemogenesis or activation of phosphatidylinositol 3-kinase.

Journal: Blood 20010101

Title: The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation.

Journal: International immunology 20010101

Title: Involvement of a herbimycin A-sensitive protein tyrosine kinase in extracellular action of HIV-1 Nef.

Journal: Immunology letters 20010101

Title: Decreased in situ insulin receptor dephosphorylation in hyperglycemia-induced insulin resistance in rat adipocytes.

Journal: Diabetes 20010101

Title: Identification of tyrosine-phosphorylated proteins associated with the nuclear envelope.

Journal: European journal of biochemistry 20010101

Title: Biomarker analysis demonstrates a hypoxic environment in the castrated rat ventral prostate gland.

Journal: Journal of cellular biochemistry 20010101

Title: Protein kinase C-mediated tyrosine phosphorylation of paxillin and focal adhesion kinase requires cytoskeletal integrity and is uncoupled to mitogen-activated protein kinase activation in human hepatoma cells.

Journal: Journal of biomedical science 20010101

Title: Role of protein phosphorylation in the inhibition of protein synthesis caused by hypoxia in rat hepatocytes.

Journal: International journal of toxicology 20010101

Title: Osmotic stress-dependent serine phosphorylation of the histidine kinase homologue DokA.

Journal: BMC biochemistry 20010101

Title: Apoptosis-induction and phosphorylation state in human pancreatic carcinoma xenografts following octreotide treatment.

Journal: Anticancer research 20010101

Title: Peptide library screening for determination of SH2 or phosphotyrosine-binding domain sequences.

Journal: Methods in enzymology 20010101

Title: Suppressive role of endogenous regucalcin in the regulation of protein phosphatase activity in rat renal cortex cytosol.

Journal: Journal of cellular biochemistry 20010101

Title: Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk.

Journal: BMC immunology 20010101

Title: Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.

Journal: Biopolymers 20010101

Title: Designing cell-permeant phosphopeptides to modulate intracellular signaling pathways.

Journal: Biopolymers 20010101

Title: Preparation and application of antibodies to phosphoamino acid sequences.

Journal: Biopolymers 20010101

Title: Tyrosine phosphorylation translocates beta-catenin from cell-->cell interface to the cytoplasm, but does not significantly enhance the LEF-1-dependent transactivating function.

Journal: Cell biology international 20010101

Title: Dimerization of receptor protein-tyrosine phosphatase alpha in living cells.

Journal: BMC cell biology 20010101

Title: Lovastatin controls signal transduction in vascular smooth muscle cells by modulating phosphorylation levels of mevalonate-independent pathways.

Journal: Basic research in cardiology 20010101

Title: A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells.

Journal: BMC immunology 20010101

Title: Lymphocyte dysmetabolism: an immunocytochemical comparative approach in IDDM and control subjects.

Journal: European journal of histochemistry : EJH 20010101

Title: Mitogenic signaling by cyclic adenosine monophosphate in chromaffin cells involves phosphatidylinositol 3-kinase activation.

Journal: Journal of cellular biochemistry. Supplement 20010101

Title: Interferon alpha2b increases paracellular permeability of renal proximal tubular LLC-PK1 cells via a mitogen activated protein kinase signaling pathway.

Journal: Renal failure 20010101

Title: Nerve growth factor stimulates the interaction of ZIP/p62 with atypical protein kinase C and targets endosomal localization: evidence for regulation of nerve growth factor-induced differentiation.

Journal: Journal of cellular biochemistry 20010101

Title: The linkage between beta1 integrin and the actin cytoskeleton is differentially regulated by tyrosine and serine/threonine phosphorylation of beta1 integrin in normal and cancerous human breast cells.

Journal: BMC cell biology 20010101

Title: Protein tyrosine phosphatase activity in human endometrium.

Journal: Reproduction, fertility, and development 20010101

Title: Expression of erythropoietin in human female reproductive organs.

Journal: Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 20010101

Title: Update on HER-2 as a target for cancer therapy: intracellular signaling pathways of ErbB2/HER-2 and family members.

Journal: Breast cancer research : BCR 20010101

Title: Relation between the flexibility of the WPD loop and the activity of the catalytic domain of protein tyrosine phosphatase SHP-1.

Journal: Journal of cellular biochemistry 20010101

Title: Grb2 dominantly associates with dynamin II in human hepatocellular carcinoma HepG2 cells.

Journal: Journal of cellular biochemistry 20010101

Title: Effect of angiotensin II on protein phosphorylation in PC12 cell line.

Journal: Folia histochemica et cytobiologica 20010101

Title: CD19, CD21, and CD22: multifaceted response regulators of B lymphocyte signal transduction.

Journal: International reviews of immunology 20010101

Title: O-phospho-L-tyrosine protects TP53 wild-type cells against ionizing radiation.

Journal: International journal of cancer 20010101

Title: v-Src-mediated phosphorylation of connexin43 on tyrosine disrupts gap junctional communication in mammalian cells.

Journal: Cell communication & adhesion 20010101

Title: Phosphotyrosine Kinase Assays as a Prescreen for Inhibitors of EGFr.

Journal: Methods in molecular medicine 20010101

Title: Phosphotyrosine phosphatase activity in ovarian carcinoma cells : stimulation by GnRH in plasma membrane.

Journal: Methods in molecular medicine 20010101

Title: Phosphatidylinositol 4-kinase assay in ovarian carcinoma cells.

Journal: Methods in molecular medicine 20010101

Title: Substrate competitive inhibitors of IGF-1 receptor kinase.

Journal: Biochemistry 20001226

Title: Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product.

Journal: Biochemical and biophysical research communications 20000907

Title: Structure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activity.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20000815

Title: Vanadium-induced kappaB-dependent transcription depends upon peroxide-induced activation of the p38 mitogen-activated protein kinase.

Journal: American journal of respiratory cell and molecular biology 20000701

Title: Arsenic inhibits NF-kappaB-mediated gene transcription by blocking IkappaB kinase activity and IkappaBalpha phosphorylation and degradation.

Journal: Archives of biochemistry and biophysics 20000501

Title: Altered actin cytoskeleton and inhibition of matrix metalloproteinase expression by vanadate and phenylarsine oxide, inhibitors of phosphotyrosine phosphatases: modulation of migration and invasion of human malignant glioma cells.

Journal: Molecular carcinogenesis 19991201

Title: Attenuation of focal adhesion kinase signaling following depletion of agonist-sensitive pools of phosphatidylinositol 4,5-bisphosphate.

Journal: Journal of neurochemistry 19991101

Title: Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in A431 cells overexpressing epidermal growth factor receptor.

Journal: British journal of pharmacology 19991101

Title: Tyrosine phosphatases as targets in metal-induced signaling in human airway epithelial cells.

Journal: American journal of respiratory cell and molecular biology 19990901

Title: Oxidative stress triggers STAT3 tyrosine phosphorylation and nuclear translocation in human lymphocytes.

Journal: The Journal of biological chemistry 19990618

Title: The proto-oncogene p120(Cbl) is a downstream substrate of the Hck protein-tyrosine kinase.

Journal: Biochemical and biophysical research communications 19990402

Title: Study on the synthesis and characterization of peptides containing phosphorylated tyrosine.

Journal: The journal of peptide research : official journal of the American Peptide Society 19990201

Title: Association of Shc, Cbl, Grb2, and Sos following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin in primary rat hepatocytes.

Journal: Biochemical and biophysical research communications 19981230

Title: Tumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc.

Journal: Molecular and cellular biology 19980901

Title: Potent inhibition of protein-tyrosine phosphatase-1B using the phosphotyrosyl mimetic fluoro-O-malonyl tyrosine (FOMT).

Journal: Bioorganic & medicinal chemistry letters 19980818

Title: Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells.

Journal: Hepatology (Baltimore, Md.) 19980501

Title: Growth inhibitory effect of bovine lactoferrin to Toxoplasma gondii tachyzoites in murine macrophages: tyrosine phosphorylation in murine macrophages induced by bovine lactoferrin.

Journal: The Journal of veterinary medical science 19980301

Title: Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases.

Journal: The Journal of biological chemistry 19971128

Title: The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix.

Journal: Journal of virology 19970601

Title: DDT stimulates c-erbB2, c-met, and STATS tyrosine phosphorylation, Grb2-Sos association, MAPK phosphorylation, and proliferation of human breast epithelial cells.

Journal: Biochemical and biophysical research communications 19970203

Title: Activation of phospholipase D is tightly coupled to the phagocytosis of Mycobacterium tuberculosis or opsonized zymosan by human macrophages.

Journal: The Journal of experimental medicine 19960801

Title: Dexamethasone inhibits the early steps of antigen receptor signaling in activated T lymphocytes.

Journal: Journal of immunology (Baltimore, Md. : 1950) 19960615

Title: Crystal structures of the human p56lck SH2 domain in complex with two short phosphotyrosyl peptides at 1.0 A and 1.8 A resolution.

Journal: Journal of molecular biology 19960301

Title: Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19960109

Title: The catalytic subunit of phosphatidylinositol 3-kinase is a substrate for the activated platelet-derived growth factor receptor, but not for middle-T antigen-pp60c-src complexes.

Journal: The Biochemical journal 19940801

Title: Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.

Journal: Molecular and cellular biology 19940301

Title: Efficient Fmoc/solid-phase peptide synthesis of O-phosphotyrosyl-containing peptides and their use as phosphatase substrates.

Journal: International journal of peptide and protein research 19940101

Title: Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19931201

Title: Fatty acid-binding protein from rat heart is phosphorylated on Tyr19 in response to insulin stimulation.

Journal: Journal of lipid research 19930801

Title: Alterations in the subcellular distribution of p21ras-GTPase activating protein in proliferating rat acinar cells.

Journal: Biochemical and biophysical research communications 19920916

Title: Efficient solid phase synthesis of mixed Thr(P)-, Ser(P)- and Tyr(P)-containing phosphopeptides by 'global' 'phosphite-triester' phosphorylation.

Journal: International journal of peptide and protein research 19920801

Title: Fmoc/solid-phase synthesis of Tyr(P)-containing peptides through t-butyl phosphate protection.

Journal: International journal of peptide and protein research 19910601

Title: Phosphotyrosine as a specificity determinant for casein kinase-2, a growth related Ser/Thr-specific protein kinase.

Journal: FEBS letters 19910225

Title: Phosphorylation of src-phosphopeptides by casein kinases-1 and -2: favourable effect of phosphotyrosine.

Journal: Biochemical and biophysical research communications 19900731

Title: Effect of vanadate on the cellular accumulation of pp15, an apparent product of insulin receptor tyrosine kinase action.

Journal: The Journal of biological chemistry 19880925

Title: Partial purification and characterization of phosphotyrosyl-protein phosphatase(s) from human erythrocyte cytosol.

Journal: Biochemical and biophysical research communications 19860529

Title: Rapid estradiol/ERalpha signaling enhances aromatase enzymatic activity in breast cancer cells.

Journal: Molecular endocrinology (Baltimore, Md.)

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Tags:21820-51-9 Molecular Formula|21820-51-9 MDL|21820-51-9 SMILES|21820-51-9 O-Phospho-l-tyrosine
Catalog No.: AA003TEW
21820-51-9,MFCD00002603
21820-51-9 | O-Phospho-l-tyrosine
Pack Size: 250mg
Purity: 95%
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Technical Information
Catalog Number: AA003TEW
Chemical Name: O-Phospho-l-tyrosine
CAS Number: 21820-51-9
Molecular Formula: C9H12NO6P
Molecular Weight: 261.1684
MDL Number: MFCD00002603
SMILES: OC(=O)[C@H](Cc1ccc(cc1)OP(=O)(O)O)N
Properties
BP: 590.1°C at 760 mmHg  
Form: Solid  
MP: 226-227°C  
Storage: Keep in dry area;-20 ℃;  
Complexity: 309  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 17  
Hydrogen Bond Acceptor Count: 7  
Hydrogen Bond Donor Count: 4  
Isotope Atom Count: 0  
Rotatable Bond Count: 5  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -2.8  
Downstream Synthesis Route
4089-07-0    21820-51-9 

[1]HelveticaChimicaActa,1945,vol.28,p.1258,1266

105-43-1    1119-62-6    57260-73-8    21820-51-9   
Phosphoricacidmono-(4-{(S)-2-(3-mercapto-propionylamino)-2-2-(3-methyl-pentanoylamino)-ethylcarbamoyl-ethyl}-phenyl)ester 

[1]JournalofMedicinalChemistry,2000,vol.43,p.1173-1179

105-43-1    1119-62-6    21820-51-9    75178-96-0   
Phosphoricacidmono-(4-{(S)-2-(3-mercapto-propionylamino)-2-3-(3-methyl-pentanoylamino)-propylcarbamoyl-ethyl}-phenyl)ester 

[1]JournalofMedicinalChemistry,2000,vol.43,p.1173-1179

105-43-1    1119-62-6    21820-51-9    51644-96-3   
Phosphoricacidmono-(4-{(S)-2-(3-mercapto-propionylamino)-2-5-(3-methyl-pentanoylamino)-pentylcarbamoyl-ethyl}-phenyl)ester 

[1]JournalofMedicinalChemistry,2000,vol.43,p.1173-1179

105-43-1    1119-62-6    21820-51-9    108467-99-8   
Phosphoricacidmono-4-((S)-2-(3-mercapto-propionylamino)-2-{3-(3-methyl-pentanoylamino)-methyl-benzylcarbamoyl}-ethyl)-phenylester 

[1]JournalofMedicinalChemistry,2000,vol.43,p.1173-1179

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Title: Ligand mobility modulates immunological synapse formation and T cell activation.

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Title: Transforming and tumorigenic activity of JAK2 by fusion to BCR: molecular mechanisms of action of a novel BCR-JAK2 tyrosine-kinase.

Journal: PloS one20120101

Title: Actin-dependent activation of serum response factor in T cells by the viral oncoprotein tip.

Journal: Cell communication and signaling : CCS20120101

Title: Structural stability of human protein tyrosine phosphatase ρ catalytic domain: effect of point mutations.

Journal: PloS one20120101

Title: KAI1 suppresses HIF-1α and VEGF expression by blocking CDCP1-enhanced Src activation in prostate cancer.

Journal: BMC cancer20120101

Title: Nef alleles from all major HIV-1 clades activate Src-family kinases and enhance HIV-1 replication in an inhibitor-sensitive manner.

Journal: PloS one20120101

Title: A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblasts.

Journal: Skeletal muscle20120101

Title: Modeling and simulation of aggregation of membrane protein LAT with molecular variability in the number of binding sites for cytosolic Grb2-SOS1-Grb2.

Journal: PloS one20120101

Title: New model of macrophage acquisition of the lymphatic endothelial phenotype.

Journal: PloS one20120101

Title: Toxin-based targeted therapy for malignant brain tumors.

Journal: Clinical & developmental immunology20120101

Title: Characterization of magnesium requirement of human 5'-tyrosyl DNA phosphodiesterase mediated reaction.

Journal: BMC research notes20120101

Title: Reduced serotonin reuptake transporter (SERT) function causes insulin resistance and hepatic steatosis independent of food intake.

Journal: PloS one20120101

Title: Oxidative stress induced interleukin-32 mRNA expression in human bronchial epithelial cells.

Journal: Respiratory research20120101

Title: Signaling-mediated control of ubiquitin ligases in endocytosis.

Journal: BMC biology20120101

Title: In silico profiling of deleterious amino acid substitutions of potential pathological importance in haemophlia A and haemophlia B.

Journal: Journal of biomedical science20120101

Title: Characterization of the effects of cross-linking of macrophage CD44 associated with increased phagocytosis of apoptotic PMN.

Journal: PloS one20120101

Title: Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab.

Journal: BMC medicine20120101

Title: N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity.

Journal: PloS one20120101

Title: The adaptor molecule Nck localizes the WAVE complex to promote actin polymerization during CEACAM3-mediated phagocytosis of bacteria.

Journal: PloS one20120101

Title: The role of C2 domains in PKC signaling.

Journal: Advances in experimental medicine and biology20120101

Title: Inhibition of protein tyrosine phosphatase improves angiogenesis via enhancing Ang-1/Tie-2 signaling in diabetes.

Journal: Experimental diabetes research20120101

Title: The malnutrition of obesity: micronutrient deficiencies that promote diabetes.

Journal: ISRN endocrinology20120101

Title: Genetic variations in APPL2 are associated with overweight and obesity in a Chinese population with normal glucose tolerance.

Journal: BMC medical genetics20120101

Title: Short-term treatment with bisphenol-A leads to metabolic abnormalities in adult male mice.

Journal: PloS one20120101

Title: Sequence variations of latent membrane protein 2A in Epstein-Barr virus-associated gastric carcinomas from Guangzhou, southern China.

Journal: PloS one20120101

Title: Epstein-Barr virus LMP2A signaling in statu nascendi mimics a B cell antigen receptor-like activation signal.

Journal: Cell communication and signaling : CCS20120101

Title: Confining domains lead to reaction bursts: reaction kinetics in the plasma membrane.

Journal: PloS one20120101

Title: The tyrosine kinase c-Src directly mediates growth factor-induced Notch-1 and Furin interaction and Notch-1 activation in pancreatic cancer cells.

Journal: PloS one20120101

Title: Internalization and down-regulation of the ALK receptor in neuroblastoma cell lines upon monoclonal antibodies treatment.

Journal: PloS one20120101

Title: Cortactin tyrosine phosphorylation promotes its deacetylation and inhibits cell spreading.

Journal: PloS one20120101

Title: Tyrosine phosphorylation of the E3 ubiquitin ligase TRIM21 positively regulates interaction with IRF3 and hence TRIM21 activity.

Journal: PloS one20120101

Title: Skin regeneration in adult axolotls: a blueprint for scar-free healing in vertebrates.

Journal: PloS one20120101

Title: Characterisation of bovine leukocyte Ig-like receptors.

Journal: PloS one20120101

Title: Computational identification and modeling of crosstalk between phosphorylation, O-β-glycosylation and methylation of FoxO3 and implications for cancer therapeutics.

Journal: International journal of molecular sciences20120101

Title: CagI is an essential component of the Helicobacter pylori Cag type IV secretion system and forms a complex with CagL.

Journal: PloS one20120101

Title: Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling.

Journal: Journal of toxicology20120101

Title: Distribution of cytoskeletal components in endothelial cells in the Guinea pig renal artery.

Journal: International journal of cell biology20120101

Title: Insulin in central nervous system: more than just a peripheral hormone.

Journal: Journal of aging research20120101

Title: Macrophage Migration and Its Regulation by CSF-1.

Journal: International journal of cell biology20120101

Title: IQGAP Family Members in Yeast, Dictyostelium, and Mammalian Cells.

Journal: International journal of cell biology20120101

Title: The amyloid precursor protein intracellular domain-fe65 multiprotein complexes: a challenge to the amyloid hypothesis for Alzheimer's disease?

Journal: International journal of Alzheimer's disease20120101

Title: A molecular model for the differential activation of STAT3 and STAT6 by the herpesviral oncoprotein tip.

Journal: PloS one20120101

Title: Protein tyrosine phosphatase 1B deficiency potentiates PERK/eIF2α signaling in brown adipocytes.

Journal: PloS one20120101

Title: Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model.

Journal: PloS one20120101

Title: Identification of JAK2 as a mediator of FIP1L1-PDGFRA-induced eosinophil growth and function in CEL.

Journal: PloS one20120101

Title: The Concept of Divergent Targeting through the Activation and Inhibition of Receptors as a Novel Chemotherapeutic Strategy: Signaling Responses to Strong DNA-Reactive Combinatorial Mimicries.

Journal: Journal of signal transduction20120101

Title: Protein Kinase A Subunit α Catalytic and A Kinase Anchoring Protein 79 in Human Placental Mitochondria.

Journal: The open biochemistry journal20120101

Title: Vimentin and PSF act in concert to regulate IbeA+ E. coli K1 induced activation and nuclear translocation of NF-κB in human brain endothelial cells.

Journal: PloS one20120101

Title: The EYA tyrosine phosphatase activity is pro-angiogenic and is inhibited by benzbromarone.

Journal: PloS one20120101

Title: Drosophila eyes absent is a novel mRNA target of the tristetraprolin (TTP) protein DTIS11.

Journal: International journal of biological sciences20120101

Title: YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation.

Journal: PloS one20120101

Title: Intra-aortic clusters undergo endothelial to hematopoietic phenotypic transition during early embryogenesis.

Journal: PloS one20120101

Title: Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

Journal: PloS one20120101

Title: The insulin receptor substrate 1 (IRS1) in intestinal epithelial differentiation and in colorectal cancer.

Journal: PloS one20120101

Title: RAB-7 antagonizes LET-23 EGFR signaling during vulva development in Caenorhabditis elegans.

Journal: PloS one20120101

Title: Protocadherin-18 is a novel differentiation marker and an inhibitory signaling receptor for CD8+ effector memory T cells.

Journal: PloS one20120101

Title: Integrin signaling in cancer cell survival and chemoresistance.

Journal: Chemotherapy research and practice20120101

Title: Human cataract mutations in EPHA2 SAM domain alter receptor stability and function.

Journal: PloS one20120101

Title: A simple matter of life and death-the trials of postnatal Beta-cell mass regulation.

Journal: International journal of endocrinology20120101

Title: Regulation of neuronal cell death by c-Abl-Hippo/MST2 signaling pathway.

Journal: PloS one20120101

Title: Impaired degradation followed by enhanced recycling of epidermal growth factor receptor caused by hypo-phosphorylation of tyrosine 1045 in RBE cells.

Journal: BMC cancer20120101

Title: The Fyn-STAT5 Pathway: A New Frontier in IgE- and IgG-Mediated Mast Cell Signaling.

Journal: Frontiers in immunology20120101

Title: Modeling the interactions of Alzheimer-related genes from the whole brain microarray data and diffusion tensor images of human brain.

Journal: BMC bioinformatics20120101

Title: Cross-phosphorylation, signaling and proliferative functions of the Tyro3 and Axl receptors in Rat2 cells.

Journal: PloS one20120101

Title: VENNTURE--a novel Venn diagram investigational tool for multiple pharmacological dataset analysis.

Journal: PloS one20120101

Title: GIT2 acts as a potential keystone protein in functional hypothalamic networks associated with age-related phenotypic changes in rats.

Journal: PloS one20120101

Title: Vitronectin increases vascular permeability by promoting VE-cadherin internalization at cell junctions.

Journal: PloS one20120101

Title: SH3 domain tyrosine phosphorylation--sites, role and evolution.

Journal: PloS one20120101

Title: PTEN gene: a model for genetic diseases in dermatology.

Journal: TheScientificWorldJournal20120101

Title: Chemical inhibition of bacterial protein tyrosine phosphatase suppresses capsule production.

Journal: PloS one20120101

Title: Fibroblast growth factor signaling potentiates VE-cadherin stability at adherens junctions by regulating SHP2.

Journal: PloS one20120101

Title: Interleukin-2 signalling is modulated by a labile disulfide bond in the CD132 chain of its receptor.

Journal: Open biology20120101

Title: Activation of human neutrophils by the anti-inflammatory mediator Esenbeckia leiocarpa leads to atypical apoptosis.

Journal: Mediators of inflammation20120101

Title: Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advances.

Journal: Frontiers in endocrinology20120101

Title: In Vivo Consequences of Disrupting SH3-Mediated Interactions of the Inducible T-Cell Kinase.

Journal: Journal of signal transduction20120101

Title: The Role of Elongin BC-Containing Ubiquitin Ligases.

Journal: Frontiers in oncology20120101

Title: Role of STAT3 in Transformation and Drug Resistance in CML.

Journal: Frontiers in oncology20120101

Title: ALK Signaling and Target Therapy in Anaplastic Large Cell Lymphoma.

Journal: Frontiers in oncology20120101

Title: Cytoskeleton in mast cell signaling.

Journal: Frontiers in immunology20120101

Title: The Role of Insulin and Insulin-Like Growth Factor-1/FoxO-Mediated Transcription for the Pathogenesis of Obesity-Associated Dementia.

Journal: Current gerontology and geriatrics research20120101

Title: Regulation of signaling at regions of cell-cell contact by endoplasmic reticulum-bound protein-tyrosine phosphatase 1B.

Journal: PloS one20120101

Title: Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration.

Journal: PloS one20120101

Title: ALK Inhibitors, a Pharmaceutical Perspective.

Journal: Frontiers in oncology20120101

Title: A Screening Method for the ALK Fusion Gene in NSCLC.

Journal: Frontiers in oncology20120101

Title: ROR1 and ROR2 in Human Malignancies: Potentials for Targeted Therapy.

Journal: Frontiers in oncology20120101

Title: Radiation induces acute alterations in neuronal function.

Journal: PloS one20120101

Title: The molecular biology of soft-tissue sarcomas and current trends in therapy.

Journal: Sarcoma20120101

Title: Role of phosphatidylinositol-3-kinase pathway in head and neck squamous cell carcinoma.

Journal: Journal of oncology20120101

Title: Intranasal 'painless' human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice.

Journal: PloS one20120101

Title: Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease.

Journal: Journal of neuroinflammation20120101

Title: All in the Family: How the APPs Regulate Neurogenesis.

Journal: Frontiers in neuroscience20120101

Title: Tyrosine phosphorylation of botulinum neurotoxin protease domains.

Journal: Frontiers in pharmacology20120101

Title: p38MAPK, ERK and PI3K signaling pathways are involved in C5a-primed neutrophils for ANCA-mediated activation.

Journal: PloS one20120101

Title: Transactivation of EGFR by LPS induces COX-2 expression in enterocytes.

Journal: PloS one20120101

Title: Cycling of Etk and Etp phosphorylation states is involved in formation of group 4 capsule by Escherichia coli.

Journal: PloS one20120101

Title: Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics.

Journal: Journal of signal transduction20120101

Title: RGS Proteins in Heart: Brakes on the Vagus.

Journal: Frontiers in physiology20120101

Title: Antihyperglycemic effect of Annona squamosa hexane extract in type 2 diabetes animal model: PTP1B inhibition, a possible mechanism of action?

Journal: Indian journal of pharmacology20120101

Title: A highly scalable peptide-based assay system for proteomics.

Journal: PloS one20120101

Title: GEP100/Arf6 is required for epidermal growth factor-induced ERK/Rac1 signaling and cell migration in human hepatoma HepG2 cells.

Journal: PloS one20120101

Title: Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death.

Journal: Molecular systems biology20120101

Title: Signaling for death: tyrosine phosphorylation in the response to glucose deprivation.

Journal: Molecular systems biology20120101

Title: Cortactin is involved in the entry of Coxiella burnetii into non-phagocytic cells.

Journal: PloS one20120101

Title: Cell invasion by Neisseria meningitidis requires a functional interplay between the focal adhesion kinase, Src and cortactin.

Journal: PloS one20120101

Title: Podosomes in migrating microglia: components and matrix degradation.

Journal: Journal of neuroinflammation20120101

Title: Carboxyamidotriazole-orotate inhibits the growth of imatinib-resistant chronic myeloid leukaemia cells and modulates exosomes-stimulated angiogenesis.

Journal: PloS one20120101

Title: Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation.

Journal: PloS one20120101

Title: Tyrosine Phosphorylation of the BRI1 Receptor Kinase Occurs via a Post-Translational Modification and is Activated by the Juxtamembrane Domain.

Journal: Frontiers in plant science20120101

Title: Fc gamma receptor CD64 modulates the inhibitory activity of infliximab.

Journal: PloS one20120101

Title: Cortactin as a target for FAK in the regulation of focal adhesion dynamics.

Journal: PloS one20120101

Title: Cortactin is a substrate of activated Cdc42-associated kinase 1 (ACK1) during ligand-induced epidermal growth factor receptor downregulation.

Journal: PloS one20120101

Title: Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors.

Journal: PloS one20120101

Title: [Somatostatin receptors and signaling cascades coupled to them].

Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii20120101

Title: HCV NS5A protein containing potential ligands for both Src homology 2 and 3 domains enhances autophosphorylation of Src family kinase Fyn in B cells.

Journal: PloS one20120101

Title: EphrinA1-EphA2 signal induces compaction and polarization of Madin-Darby canine kidney cells by inactivating Ezrin through negative regulation of RhoA.

Journal: The Journal of biological chemistry20111223

Title: Comparative proteomics and phosphoproteomics analyses of DHEA-induced on hepatic lipid metabolism in broiler chickens.

Journal: Steroids20111220

Title: Interleukin-2 signaling pathway analysis by quantitative phosphoproteomics.

Journal: Journal of proteomics20111210

Title: MAPKKK-independent regulation of the Hog1 stress-activated protein kinase in Candida albicans.

Journal: The Journal of biological chemistry20111209

Title: Comparison of three quantitative phosphoproteomic strategies to study receptor tyrosine kinase signaling.

Journal: Journal of proteome research20111202

Title: Impaired Rho GTPase activation abrogates cell polarization and migration in macrophages with defective lipolysis.

Journal: Cellular and molecular life sciences : CMLS20111201

Title: Synthetic osteogenic growth peptide promotes differentiation of human bone marrow mesenchymal stem cells to osteoblasts via RhoA/ROCK pathway.

Journal: Molecular and cellular biochemistry20111201

Title: Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiation.

Journal: The Journal of investigative dermatology20111201

Title: MICALs in control of the cytoskeleton, exocytosis, and cell death.

Journal: Cellular and molecular life sciences : CMLS20111201

Title: Recent patents related to phosphorylation signaling pathway on cancer.

Journal: Recent patents on DNA & gene sequences20111201

Title: PKCβ-dependent phosphorylation of the glycine transporter 1.

Journal: Neurochemistry international20111201

Title: Mediators of the Jak/STAT signaling pathway in human spermatozoa.

Journal: Biology of reproduction20111201

Title: Neuronal Shc: a gene of longevity in the brain?

Journal: Medical hypotheses20111201

Title: Evaluation of HCD- and CID-type fragmentation within their respective detection platforms for murine phosphoproteomics.

Journal: Molecular & cellular proteomics : MCP20111201

Title: Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa.

Journal: Human reproduction (Oxford, England)20111201

Title: Discrimination between peptide O-sulfo- and O-phosphotyrosine residues by negative ion mode electrospray tandem mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry20111201

Title: SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling.

Journal: Journal of immunology (Baltimore, Md. : 1950)20111201

Title: Lyn is a redox sensor that mediates leukocyte wound attraction in vivo.

Journal: Nature20111201

Title: Cytokine signaling: birth of a pathway.

Journal: Journal of immunology (Baltimore, Md. : 1950)20111201

Title: Pillars article: Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science. 1992. 257: 809-813.

Journal: Journal of immunology (Baltimore, Md. : 1950)20111201

Title: Intraspecific and interspecific interactions among proteins regulating exopolysaccharide synthesis in Streptococcus thermophilus, Streptococcus iniae, and Lactococcus lactis subsp. cremoris and the assessment of potential lateral gene transfer.

Journal: Canadian journal of microbiology20111201

Title: The human cytomegalovirus UL11 protein interacts with the receptor tyrosine phosphatase CD45, resulting in functional paralysis of T cells.

Journal: PLoS pathogens20111201

Title: PIM kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer cells.

Journal: Oncotarget20111201

Title: Phosphatase inhibitor, sodium stibogluconate, in combination with interferon (IFN) alpha 2b: phase I trials to identify pharmacodynamic and clinical effects.

Journal: Oncotarget20111201

Title: Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin.

Journal: PLoS biology20111201

Title: Identification of MET and SRC activation in melanoma cell lines showing primary resistance to PLX4032.

Journal: Neoplasia (New York, N.Y.)20111201

Title: Duox, Flotillin-2, and Src42A are required to activate or delimit the spread of the transcriptional response to epidermal wounds in Drosophila.

Journal: PLoS genetics20111201

Title: AHI-1: a novel signaling protein and potential therapeutic target in human leukemia and brain disorders.

Journal: Oncotarget20111201

Title: [Regulation of hepatic lipid metabolism by adiponectin via IRS-2 phosphorylation in OLETF rats].

Journal: Zhonghua yi xue za zhi20111129

Title: Tyrosine phosphorylation as a conformational switch: a case study of integrin β3 cytoplasmic tail.

Journal: The Journal of biological chemistry20111125

Title: Dynamic substrate enhancement for the identification of specific, second-site-binding fragments targeting a set of protein tyrosine phosphatases.

Journal: Chembiochem : a European journal of chemical biology20111125

Title: Conformational basis for substrate recruitment in protein tyrosine phosphatase 10D.

Journal: Biochemistry20111122

Title: Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling.

Journal: Blood20111117

Title: Form of dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A nonphosphorylated at tyrosine 145 and 147 is enriched in the nuclei of astroglial cells, adult hippocampal progenitors, and some cholinergic axon terminals.

Journal: Neuroscience20111110

Title: Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma through upregulation of FAK and Src.

Journal: The Journal of investigative dermatology20111101

Title: Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways.

Journal: Human molecular genetics20111101

Title: IgA1 immune complexes from pediatric patients with IgA nephropathy activate cultured human mesangial cells.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20111101

Title: RF1 knockout allows ribosomal incorporation of unnatural amino acids at multiple sites.

Journal: Nature chemical biology20111101

Title: Simultaneous identification of tyrosine phosphorylation and sulfation sites utilizing tyrosine-specific bromination.

Journal: Journal of the American Society for Mass Spectrometry20111101

Title: The JAK-STAT pathway controls Plasmodium vivax load in early stages of Anopheles aquasalis infection.

Journal: PLoS neglected tropical diseases20111101

Title: Murid herpesvirus-4 exploits dendritic cells to infect B cells.

Journal: PLoS pathogens20111101

Title: Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells.

Journal: Oncotarget20111101

Title: Mutations of TFAP2B in congenital heart disease patients in Mysore, South India.

Journal: The Indian journal of medical research20111101

Title: Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations.

Journal: Open biology20111101

Title: Consensus substrate sequence for protein-tyrosine phosphatase receptor type Z.

Journal: The Journal of biological chemistry20111028

Title: A self-immobilizing and fluorogenic unnatural amino acid that mimics phosphotyrosine.

Journal: Chemical communications (Cambridge, England)20111021

Title: Impact of epididymal maturation, ejaculation and in vitro capacitation on tyrosine phosphorylation patterns exhibited of boar (Sus domesticus) spermatozoa.

Journal: Theriogenology20111015

Title: Rapid and reproducible single-stage phosphopeptide enrichment of complex peptide mixtures: application to general and phosphotyrosine-specific phosphoproteomics experiments.

Journal: Analytical chemistry20111015

Title: Myeloid differentiation factor-2 interacts with Lyn kinase and is tyrosine phosphorylated following lipopolysaccharide-induced activation of the TLR4 signaling pathway.

Journal: Journal of immunology (Baltimore, Md. : 1950)20111015

Title: Structure and substrate recognition of the Staphylococcus aureus protein tyrosine phosphatase PtpA.

Journal: Journal of molecular biology20111014

Title: Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis.

Journal: Cell20111014

Title: Comparative properties of caveolar and noncaveolar preparations of kidney Na+/K+-ATPase.

Journal: Biochemistry20111011

Title: A phosphoarginine containing peptide as an artificial SH2 ligand.

Journal: Chemical communications (Cambridge, England)20111007

Title: Phosphoproteomic mass spectrometry profiling links Src family kinases to escape from HER2 tyrosine kinase inhibition.

Journal: Oncogene20111006

Title: Functional and molecular interactions between Rac1 and FE65.

Journal: Neuroreport20111005

Title: 1H, 13C and 15N backbone and side-chain chemical shift assignment of the Fyn SH2 domain and its complex with a phosphotyrosine peptide.

Journal: Biomolecular NMR assignments20111001

Title: The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling.

Journal: Haematologica20111001

Title: Mapping protein interactions by combining antibody affinity maturation and mass spectrometry.

Journal: Analytical biochemistry20111001

Title: Attachment of HeLa cells during early G1 phase.

Journal: Histochemistry and cell biology20111001

Title: APPL1 mediates adiponectin-induced LKB1 cytosolic localization through the PP2A-PKCzeta signaling pathway.

Journal: Molecular endocrinology (Baltimore, Md.)20111001

Title: Pleiotropic functions of EAPII/TTRAP/TDP2: cancer development, chemoresistance and beyond.

Journal: Cell cycle (Georgetown, Tex.)20111001

Title: Chlamydia trachomatis co-opts the FGF2 signaling pathway to enhance infection.

Journal: PLoS pathogens20111001

Title: Potentiation of Helicobacter pylori CagA protein virulence through homodimerization.

Journal: The Journal of biological chemistry20110923

Title: Focal adhesion kinase promotes integrin adhesion dynamics necessary for chemotropic turning of nerve growth cones.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20110921

Title: NADPH-oxidase-dependent reactive oxygen species mediate EGFR transactivation by FPRL1 in WKYMVm-stimulated human lung cancer cells.

Journal: Free radical biology & medicine20110915

Title: Diagnostic cyclisation reactions which follow phosphate transfer to carboxylate anion centres for energised [M-H]- anions of pTyr-containing peptides.

Journal: Rapid communications in mass spectrometry : RCM20110915

Title: Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain.

Journal: Biochemistry20110906

Title: Secretome compartment is a valuable source of biomarkers for cancer-relevant pathways.

Journal: Journal of proteome research20110902

Title: MEMO associated with an ErbB2 receptor phosphopeptide reveals a new phosphotyrosine motif.

Journal: FEBS letters20110902

Title: Rapid phospho-turnover by receptor tyrosine kinases impacts downstream signaling and drug binding.

Journal: Molecular cell20110902

Title: Integrin-associated tyrosine kinase FAK affects Cbfa1 expression.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society20110901

Title: Dual-specificity phosphatase DUSP6 has tumor-promoting properties in human glioblastomas.

Journal: Oncogene20110901

Title: Influence of insulin on glutamine synthetase in the Müller glial cells of retina.

Journal: Metabolic brain disease20110901

Title: Progesterone synthesis by human placental mitochondria is sensitive to PKA inhibition by H89.

Journal: The international journal of biochemistry & cell biology20110901

Title: PAK1-Nck regulates cyclin D1 promoter activity in response to prolactin.

Journal: Molecular endocrinology (Baltimore, Md.)20110901

Title: IGF-I stimulates cooperative interaction between the IGF-I receptor and CSK homologous kinase that regulates SHPS-1 phosphorylation in vascular smooth muscle cells.

Journal: Molecular endocrinology (Baltimore, Md.)20110901

Title: The p75 receptor mediates axon growth inhibition through an association with PIR-B.

Journal: Cell death & disease20110901

Title: Helicobacter pylori exploits a unique repertoire of type IV secretion system components for pilus assembly at the bacteria-host cell interface.

Journal: PLoS pathogens20110901

Title: Restoration of IFNγR subunit assembly, IFNγ signaling and parasite clearance in Leishmania donovani infected macrophages: role of membrane cholesterol.

Journal: PLoS pathogens20110901

Title: Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control.

Journal: PLoS pathogens20110901

Title: ESRRA-C11orf20 is a recurrent gene fusion in serous ovarian carcinoma.

Journal: PLoS biology20110901

Title: Quantitative in vivo analyses reveal calcium-dependent phosphorylation sites and identifies a novel component of the Toxoplasma invasion motor complex.

Journal: PLoS pathogens20110901

Title: Epidermal growth factor receptor signalling contributes to osteoblastic stromal cell proliferation, osteoclastogenesis and disease progression in giant cell tumour of bone.

Journal: Histopathology20110901

Title: The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85.

Journal: The EMBO journal20110831

Title: Correlation between the destruction of tight junction by patulin treatment and increase of phosphorylation of ZO-1 in Caco-2 human colon cancer cells.

Journal: Toxicology letters20110828

Title: Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding.

Journal: The EMBO journal20110817

Title: Cyclin-dependent kinase 1 (CDK1)-mediated phosphorylation of enhancer of zeste 2 (Ezh2) regulates its stability.

Journal: The Journal of biological chemistry20110812

Title: Discrimination between 5-hydroxymethylcytosine and 5-methylcytosine by a chemically designed peptide.

Journal: Chemical communications (Cambridge, England)20110807

Title: Excitation-transcription coupling in skeletal muscle: the molecular pathways of exercise.

Journal: Biological reviews of the Cambridge Philosophical Society20110801

Title: Characterization of a TiO₂ enrichment method for label-free quantitative phosphoproteomics.

Journal: Methods (San Diego, Calif.)20110801

Title: Toward a comprehensive characterization of the phosphotyrosine proteome.

Journal: Cellular signalling20110801

Title: SH2B1β regulates N-cadherin levels, cell-cell adhesion and nerve growth factor-induced neurite initiation.

Journal: Journal of cellular physiology20110801

Title: Increased abundance of the adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif (APPL1) in patients with obesity and type 2 diabetes: evidence for altered adiponectin signalling.

Journal: Diabetologia20110801

Title: Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice.

Journal: Diabetologia20110801

Title: Antagonism of the Stat3-Stat3 protein dimer with salicylic acid based small molecules.

Journal: ChemMedChem20110801

Title: TLRs innate immunereceptors and Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) CIDR1α-driven human polyclonal B-cell activation.

Journal: Acta tropica20110801

Title: Nucleocytoplasmic transfer of cyclin dependent kinase 5 and its binding to puromycin-sensitive aminopeptidase in Dictyostelium discoideum.

Journal: Histochemistry and cell biology20110801

Title: Cytoskeletal polarity mediates localized induction of the heart progenitor lineage.

Journal: Nature cell biology20110801

Title: Integrating signals from the T-cell receptor and the interleukin-2 receptor.

Journal: PLoS computational biology20110801

Title: A transient increase in total head phosphotyrosine levels is observed upon the emergence of Aedes aegypti from the pupal stage.

Journal: Memorias do Instituto Oswaldo Cruz20110801

Title: Focal adhesion proteins talin-1 and vinculin negatively affect paxillin phosphorylation and limit retroviral infection.

Journal: Journal of molecular biology20110729

Title: Protein interactions among Fe65, the low-density lipoprotein receptor-related protein, and the amyloid precursor protein.

Journal: Biochemistry20110719

Title: ADP-ribosylation of arginine.

Journal: Amino acids20110701

Title: Phosphoproteomics perspective on plant signal transduction and tyrosine phosphorylation.

Journal: Phytochemistry20110701

Title: Tyrosine phosphorylation of actin during microcyst formation and germination in Polysphondylium pallidum.

Journal: Protist20110701

Title: Acetylome and phosphoproteome modifications in imatinib resistant chronic myeloid leukaemia cells treated with valproic acid.

Journal: Leukemia research20110701

Title: Thrombospondin-1 opens the paracellular pathway in pulmonary microvascular endothelia through EGFR/ErbB2 activation.

Journal: American journal of physiology. Lung cellular and molecular physiology20110701

Title: Specificity of HCPTP variants toward EphA2 tyrosines by quantitative selected reaction monitoring.

Journal: Protein science : a publication of the Protein Society20110701

Title: TTBK2 kinase substrate specificity and the impact of spinocerebellar-ataxia-causing mutations on expression, activity, localization and development.

Journal: The Biochemical journal20110701

Title: Quantitative phospho-proteomic profiling of hepatocyte growth factor (HGF)-MET signaling in colorectal cancer.

Journal: Journal of proteome research20110701

Title: Vav1 is a crucial molecule in monocytic/macrophagic differentiation of myeloid leukemia-derived cells.

Journal: Cell and tissue research20110701

Title: Targeting invadopodia to block breast cancer metastasis.

Journal: Oncotarget20110701

Title: Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148.

Journal: The Journal of biological chemistry20110624

Title: Phospholipase C-β3 regulates FcɛRI-mediated mast cell activation by recruiting the protein phosphatase SHP-1.

Journal: Immunity20110624

Title: Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology20110620

Title: Particle stimulation dephosphorylates glutathione S-transferase π1 of epithelial cells.

Journal: Toxicology20110618

Title: PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer.

Journal: Oncogene20110602

Title: Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation.

Journal: Blood20110602

Title: Analysis of dynamic tyrosine phosphoproteome in LFA-1 triggered migrating T-cells.

Journal: Journal of cellular physiology20110601

Title: Antibody-free peptide substrate screening of serine/threonine kinase (protein kinase A) with a biotinylated detection probe.

Journal: Analytical biochemistry20110601

Title: Identification of Dermcidin as a novel binding protein of Nck1 and characterization of its role in promoting cell migration.

Journal: Biochimica et biophysica acta20110601

Title: Rin-like, a novel regulator of endocytosis, acts as guanine nucleotide exchange factor for Rab5a and Rab22.

Journal: Biochimica et biophysica acta20110601

Title: Protein tyrosine phosphorylation and zona binding ability of in vitro capacitated and cryopreserved buffalo spermatozoa.

Journal: Theriogenology20110601

Title: Characterization and role of NUMB in the human extravillous trophopblast.

Journal: Placenta20110601

Title: Tensin2 is a novel mediator in thrombopoietin (TPO)-induced cellular proliferation by promoting Akt signaling.

Journal: Cell cycle (Georgetown, Tex.)20110601

Title: Eukaryotic-like Ser/Thr protein kinases SpkC/F/K are involved in phosphorylation of GroES in the Cyanobacterium synechocystis.

Journal: DNA research : an international journal for rapid publication of reports on genes and genomes20110601

Title: Urban PM2.5 induces ROS generation and RBC damage in COPD patients.

Journal: Frontiers in bioscience (Elite edition)20110601

Title: Metabolism and brain cancer.

Journal: Clinics (Sao Paulo, Brazil)20110601

Title: Identification of nitrotyrosine containing peptides using combined fractional diagonal chromatography (COFRADIC) and off-line nano-LC-MALDI.

Journal: Journal of the American Society for Mass Spectrometry20110601

Title: The strictly conserved Arg-321 residue in the active site of Escherichia coli topoisomerase I plays a critical role in DNA rejoining.

Journal: The Journal of biological chemistry20110527

Title: Potent and selective phosphopeptide mimetic prodrugs targeted to the Src homology 2 (SH2) domain of signal transducer and activator of transcription 3.

Journal: Journal of medicinal chemistry20110526

Title: Role of β-Pix in corneal epithelial cell migration on fibronectin.

Journal: Investigative ophthalmology & visual science20110516

Title: A Dictyostelium SH2 adaptor protein required for correct DIF-1 signaling and pattern formation.

Journal: Developmental biology20110515

Title: Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain.

Journal: Journal of molecular biology20110513

Title: Structure analysis of the Staphylococcus aureus UDP-N-acetyl-mannosamine dehydrogenase Cap5O involved in capsular polysaccharide biosynthesis.

Journal: The Journal of biological chemistry20110513

Title: AS160 phosphotyrosine-binding domain constructs inhibit insulin-stimulated GLUT4 vesicle fusion with the plasma membrane.

Journal: The Journal of biological chemistry20110513

Title: Focal adhesion kinase (FAK) binds RET kinase via its FERM domain, priming a direct and reciprocal RET-FAK transactivation mechanism.

Journal: The Journal of biological chemistry20110513

Title: hTID-1 defines a novel regulator of c-Met Receptor signaling in renal cell carcinomas.

Journal: Oncogene20110512

Title: Physiopathological function of hematoside (GM3 ganglioside).

Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences20110511

Title: A role for nucleotides in support of breast cancer angiogenesis: heterologous receptor signalling.

Journal: British journal of cancer20110510

Title: Optimization of immunoaffinity enrichment and detection: toward a comprehensive characterization of the phosphotyrosine proteome of K562 cells by liquid chromatography-mass spectrometry.

Journal: The Analyst20110507

Title: Mitogen-activated protein kinase (MAPK) phosphatase 3-mediated cross-talk between MAPKs ERK2 and p38alpha.

Journal: The Journal of biological chemistry20110506

Title: The metalloprotease, NN-PF3 from Naja naja venom inhibits platelet aggregation primarily by affecting α2β1 integrin.

Journal: Annals of hematology20110501

Title: Accreta complicating complete placenta previa is characterized by reduced systemic levels of vascular endothelial growth factor and by epithelial-to-mesenchymal transition of the invasive trophoblast.

Journal: American journal of obstetrics and gynecology20110501

Title: The integrin-binding motif RGDS induces protein tyrosine phosphorylation without activation in Bufo arenarum (Amphibia) oocytes.

Journal: Reproduction (Cambridge, England)20110501

Title: Density of human bone marrow stromal cells regulates commitment to vascular lineages.

Journal: Stem cell research20110501

Title: Ablation of PI3K p110-α prevents high-fat diet-induced liver steatosis.

Journal: Diabetes20110501

Title: Genetic ablation of cGMP-dependent protein kinase type I causes liver inflammation and fasting hyperglycemia.

Journal: Diabetes20110501

Title: Nobiletin attenuates VLDL overproduction, dyslipidemia, and atherosclerosis in mice with diet-induced insulin resistance.

Journal: Diabetes20110501

Title: Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity.

Journal: Oncotarget20110501

Title: [Adiponectin decreases insulin receptor substrate-1 phosphorylation in the liver of OLETF rats possibly through nuclear factor-κB signaling pathway].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University20110501

Title: Phosphopeptides designed for 5-methylcytosine recognition.

Journal: Biochemistry20110426

Title: Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia.

Journal: The Journal of biological chemistry20110422

Title: Separation of phosphorylated peptides utilizing dual pH- and temperature-responsive chromatography.

Journal: Journal of chromatography. A20110415

Title: Disassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosis.

Journal: Experimental cell research20110415

Title: Interactions between GIPC-APPL and GIPC-TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes.

Journal: Archives of biochemistry and biophysics20110415

Title: Trask phosphorylation defines the reverse mode of a phosphotyrosine signaling switch that underlies cell anchorage state.

Journal: Cell cycle (Georgetown, Tex.)20110415

Title: Tyrosine phosphorylation modulates store-operated calcium entry in cultured rat epididymal basal cells.

Journal: Journal of cellular physiology20110401

Title: Differential G-protein-coupled receptor phosphorylation provides evidence for a signaling bar code.

Journal: The Journal of biological chemistry20110401

Title: Effects of the plasmid-encoded toxin of enteroaggregative Escherichia coli on focal adhesion complexes.

Journal: FEMS immunology and medical microbiology20110401

Title: Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment.

Journal: Biochimica et biophysica acta20110401

Title: The adapter protein APPL1 links FSH receptor to inositol 1,4,5-trisphosphate production and is implicated in intracellular Ca(2+) mobilization.

Journal: Endocrinology20110401

Title: Novel fat depot-specific mechanisms underlie resistance to visceral obesity and inflammation in 11 β-hydroxysteroid dehydrogenase type 1-deficient mice.

Journal: Diabetes20110401

Title: Intracellular trafficking considerations in the development of natural ligand-drug molecular conjugates for cancer.

Journal: Annals of biomedical engineering20110401

Title: Focal adhesion remodeling is crucial for glucose-stimulated insulin secretion and involves activation of focal adhesion kinase and paxillin.

Journal: Diabetes20110401

Title: Phosphoproteome analysis of the pathogenic bacterium Helicobacter pylori reveals over-representation of tyrosine phosphorylation and multiply phosphorylated proteins.

Journal: Proteomics20110401

Title: Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling.

Journal: Cellular oncology (Dordrecht)20110401

Title: Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

Journal: Nature cell biology20110401

Title: Protein tyrosine phosphatase assays.

Journal: Current protocols in immunology20110401

Title: Association of PTPN22 1858T/T genotype with type 1 diabetes, Graves' disease but not with rheumatoid arthritis in Russian population.

Journal: Aging20110401

Title: Reversing B cell aging.

Journal: Aging20110401

Title: The MARCH family E3 ubiquitin ligase K5 alters monocyte metabolism and proliferation through receptor tyrosine kinase modulation.

Journal: PLoS pathogens20110401

Title: Phosphorylation-dependent differential regulation of plant growth, cell death, and innate immunity by the regulatory receptor-like kinase BAK1.

Journal: PLoS genetics20110401

Title: Substrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2.

Journal: Biochemistry20110329

Title: ARAP3 inhibits peritoneal dissemination of scirrhous gastric carcinoma cells by regulating cell adhesion and invasion.

Journal: Oncogene20110324

Title: Identification and functional analysis of a new phosphorylation site (Y398) in the SH3 domain of Abi-1.

Journal: FEBS letters20110323

Title: Antitumor activity of BIBF 1120, a triple angiokinase inhibitor, and use of VEGFR2+pTyr+ peripheral blood leukocytes as a pharmacodynamic biomarker in vivo.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20110315

Title: T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component.

Journal: The Journal of biological chemistry20110304

Title: The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions.

Journal: The Journal of biological chemistry20110304

Title: Analysis of phosphotyrosine signaling in glioblastoma identifies STAT5 as a novel downstream target of ΔEGFR.

Journal: Journal of proteome research20110304

Title: Identification of phosphoproteins associated with human neutrophil granules following chemotactic peptide stimulation.

Journal: Molecular & cellular proteomics : MCP20110301

Title: Integration of proteomic analyses to monitor the activity status of phosphorylation signaling.

Journal: Journal of proteomics20110301

Title: Globular and full-length adiponectin induce NO-dependent vasodilation in resistance arteries of Zucker lean but not Zucker diabetic fatty rats.

Journal: American journal of hypertension20110301

Title: Proteomic analysis of HIV-infected macrophages.

Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology20110301

Title: Protein-protein interactions among the components of the biosynthetic machinery responsible for exopolysaccharide production in Streptococcus thermophilus MR-1C.

Journal: Journal of applied microbiology20110301

Title: Suppressor of cytokine signaling 1 interacts with oncogenic lymphocyte-specific protein tyrosine kinase.

Journal: Oncology reports20110301

Title: Rapid analysis of phosphoamino acids from phosvitin by near-infrared cyanine 1-(ε-succinimydyl-hexanoate)-1'-methyl-3,3,3',3'-tetramethyl-indocarbocyanine-5,5'-disulfonate potassium derivatization and polyacrylamide-coated CE with LIF detection.

Journal: Electrophoresis20110301

Title: CAERUS: predicting CAncER oUtcomeS using relationship between protein structural information, protein networks, gene expression data, and mutation data.

Journal: PLoS computational biology20110301

Title: Identifying changes in the synaptic proteome of cirrhotic alcoholic superior frontal gyrus.

Journal: Current neuropharmacology20110301

Title: Dyrk1A Positively Stimulates ASK1-JNK Signaling Pathway during Apoptotic Cell Death.

Journal: Experimental neurobiology20110301

Title: Syk-dependent phosphorylation of CLEC-2: a novel mechanism of hem-immunoreceptor tyrosine-based activation motif signaling.

Journal: The Journal of biological chemistry20110211

Title: Identification of new substrates of the protein-tyrosine phosphatase PTP1B by Bayesian integration of proteome evidence.

Journal: The Journal of biological chemistry20110211

Title: Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells.

Journal: The Journal of biological chemistry20110211

Title: Proteomic characterization of plasma membrane-proximal T cell activation responses.

Journal: The Journal of biological chemistry20110211

Title: Mechanistic studies of Ser/Thr dehydration catalyzed by a member of the LanL lanthionine synthetase family.

Journal: Biochemistry20110208

Title: Cross-correlated fluctuation analysis reveals phosphorylation-regulated paxillin-FAK complexes in nascent adhesions.

Journal: Biophysical journal20110202

Title: mTOR partly mediates insulin resistance by phosphorylation of insulin receptor substrate-1 on serine(307) residues after burn.

Journal: Burns : journal of the International Society for Burn Injuries20110201

Title: Beta-carotene affects gene expression in lungs of male and female Bcmo1 (-/-) mice in opposite directions.

Journal: Cellular and molecular life sciences : CMLS20110201

Title: In-silico characterization of the effects of phosphorylated tyrosines 86 and 106 on structure and binding of MAL: insight into hyperinflammatory response to infection by the human malaria parasites.

Journal: Journal of receptor and signal transduction research20110201

Title: Arsenic stress activates MAP kinase in rice roots and leaves.

Journal: Archives of biochemistry and biophysics20110201

Title: Molecular pharmacology in a simple model system: implicating MAP kinase and phosphoinositide signalling in bipolar disorder.

Journal: Seminars in cell & developmental biology20110201

Title: ABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1.

Journal: Leukemia20110201

Title: Receptor tyrosine phosphatase PTPγ is a regulator of spinal cord neurogenesis.

Journal: Molecular and cellular neurosciences20110201

Title: A systems view of epithelial-mesenchymal transition signaling states.

Journal: Clinical & experimental metastasis20110201

Title: Parallel evolution of a type IV secretion system in radiating lineages of the host-restricted bacterial pathogen Bartonella.

Journal: PLoS genetics20110201

Title: Autoimmune hypoglycemia in a patient with characterization of insulin receptor autoantibodies.

Journal: Diabetes & metabolism journal20110201

Title: Andrographolide attenuates tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes.

Journal: Molecular and cellular endocrinology20110130

Title: Leptin receptor activation increases Sam68 tyrosine phosphorylation and expression in human trophoblastic cells.

Journal: Molecular and cellular endocrinology20110130

Title: The ShcA phosphotyrosine docking protein uses distinct mechanisms to regulate myocyte and global heart function.

Journal: Circulation research20110121

Title: An adjacent arginine, and the phosphorylated tyrosine in the c-Met receptor target sequence, dictates the orientation of c-Cbl binding.

Journal: FEBS letters20110121

Title: Shp2 protein tyrosine phosphatase inhibitor activity of estramustine phosphate and its triterpenoid analogs.

Journal: Bioorganic & medicinal chemistry letters20110115

Title: A CSF-1 receptor phosphotyrosine 559 signaling pathway regulates receptor ubiquitination and tyrosine phosphorylation.

Journal: The Journal of biological chemistry20110114

Title: Regulated phosphorylation of a major UDP-glucuronosyltransferase isozyme by tyrosine kinases dictates endogenous substrate selection for detoxification.

Journal: The Journal of biological chemistry20110114

Title: Primary tumor xenografts of human lung adeno and squamous cell carcinoma express distinct proteomic signatures.

Journal: Journal of proteome research20110107

Title: Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration.

Journal: The Journal of biological chemistry20110107

Title: Negative regulation of TGFβ signaling by the kinase LKB1 and the scaffolding protein LIP1.

Journal: The Journal of biological chemistry20110107

Title: TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage.

Journal: The Journal of biological chemistry20110107

Title: Proteomic analysis of native hepatocyte nuclear factor-4α (HNF4α) isoforms, phosphorylation status, and interactive cofactors.

Journal: The Journal of biological chemistry20110107

Title: α-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways.

Journal: British journal of cancer20110104

Title: Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo.

Journal: British journal of cancer20110104

Title: A Chinese Herbal Decoction, Dang Gui Bu Xue Tang, Prepared from Radix Astragali and Radix Angelicae sinensis, Ameliorates Insulin Resistance Induced by A High-Fructose Diet in Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM20110101

Title: Suppression of Heregulin-β1/HER2-Modulated Invasive and Aggressive Phenotype of Breast Carcinoma by Pterostilbene via Inhibition of Matrix Metalloproteinase-9, p38 Kinase Cascade and Akt Activation.

Journal: Evidence-based complementary and alternative medicine : eCAM20110101

Title: The interaction of Jagged-1 cytoplasmic tail with afadin PDZ domain is local, folding-independent, and tuned by phosphorylation.

Journal: Journal of molecular recognition : JMR20110101

Title: Grb7 binds to Hax-1 and undergoes an intramolecular domain association that offers a model for Grb7 regulation.

Journal: Journal of molecular recognition : JMR20110101

Title: Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes.

Journal: Molecular & cellular proteomics : MCP20110101

Title: Prep1 controls insulin glucoregulatory function in liver by transcriptional targeting of SHP1 tyrosine phosphatase.

Journal: Diabetes20110101

Title: Cloning, sequence identification, and tissue expression analysis of novel chicken NYGGF4 gene.

Journal: Molecular and cellular biochemistry20110101

Title: Serine residues in the LAT adaptor are essential for TCR-dependent signal transduction.

Journal: Journal of leukocyte biology20110101

Title: Ciona intestinalis Noto4 contains a phosphotyrosine interaction domain and is involved in the midline intercalation of notochord cells.

Journal: The International journal of developmental biology20110101

Title: Collagen binding specificity of the discoidin domain receptors: binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1.

Journal: Matrix biology : journal of the International Society for Matrix Biology20110101

Title: Osmotic stress stimulates phosphorylation and cellular expression of heat shock proteins in rhesus macaque sperm.

Journal: Journal of andrology20110101

Title: Light-induced phosphorylation of crystallins in the retinal pigment epithelium.

Journal: International journal of biological macromolecules20110101

Title: Design and NMR studies of cyclic peptides targeting the N-terminal domain of the protein tyrosine phosphatase YopH.

Journal: Chemical biology & drug design20110101

Title: A fluorescence lifetime-based assay for abelson kinase.

Journal: Journal of biomolecular screening20110101

Title: EGFR activation monitored by SW-FCCS in live cells.

Journal: Frontiers in bioscience (Elite edition)20110101

Title: Inhibition of Epidermal Growth Factor Receptor and PI3K/Akt Signaling Suppresses Cell Proliferation and Survival through Regulation of Stat3 Activation in Human Cutaneous Squamous Cell Carcinoma.

Journal: Journal of skin cancer20110101

Title: Loss of function of e-cadherin in embryonic stem cells and the relevance to models of tumorigenesis.

Journal: Journal of oncology20110101

Title: APP processing in Alzheimer's disease.

Journal: Molecular brain20110101

Title: Shb deficient mice display an augmented TH2 response in peripheral CD4+ T cells.

Journal: BMC immunology20110101

Title: Optimization of peptide density on microarray surface for quantitative phosphoproteomics.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry20110101

Title: Proteomic snapshot of the EGF-induced ubiquitin network.

Journal: Molecular systems biology20110101

Title: Radiation rescue: mesenchymal stromal cells protect from lethal irradiation.

Journal: PloS one20110101

Title: Irreversible AE1 tyrosine phosphorylation leads to membrane vesiculation in G6PD deficient red cells.

Journal: PloS one20110101

Title: Bim and Mcl-1 exert key roles in regulating JAK2V617F cell survival.

Journal: BMC cancer20110101

Title: Escharectomy and allografting during shock stage reduces insulin resistance induced by major burn.

Journal: Journal of burn care & research : official publication of the American Burn Association20110101

Title: Biofilm development on Caenorhabditis elegans by Yersinia is facilitated by quorum sensing-dependent repression of type III secretion.

Journal: PLoS pathogens20110101

Title: Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma.

Journal: PloS one20110101

Title: Morphological and molecular alterations in 1,2 dimethylhydrazine and azoxymethane induced colon carcinogenesis in rats.

Journal: Journal of biomedicine & biotechnology20110101

Title: Reverse transcription of the pFOXC mitochondrial retroplasmids of Fusarium oxysporum is protein primed.

Journal: Mobile DNA20110101

Title: Repetitive peroxide exposure reveals pleiotropic mitogen-activated protein kinase signaling mechanisms.

Journal: Journal of signal transduction20110101

Title: Issues associated with the use of phosphospecific antibodies to localise active and inactive pools of GSK-3 in cells.

Journal: Biology direct20110101

Title: Phosphoproteomics characterization of novel phosphorylated sites of lens proteins from normal and cataractous human eye lenses.

Journal: Molecular vision20110101

Title: High- and low-affinity epidermal growth factor receptor-ligand interactions activate distinct signaling pathways.

Journal: PloS one20110101

Title: Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system.

Journal: PLoS biology20110101

Title: Tyrosine phosphorylation of tau by the SRC family kinases lck and fyn.

Journal: Molecular neurodegeneration20110101

Title: Identification of ligand binding sites of proteins using the Gaussian Network Model.

Journal: PloS one20110101

Title: Activation of MyD88 signaling upon staphylococcal enterotoxin binding to MHC class II molecules.

Journal: PloS one20110101

Title: Hierarchical graphs for rule-based modeling of biochemical systems.

Journal: BMC bioinformatics20110101

Title: Differential gene expression in liver and small intestine from lactating rats compared to age-matched virgin controls detects increased mRNA of cholesterol biosynthetic genes.

Journal: BMC genomics20110101

Title: Protein S blocks the extrinsic apoptotic cascade in tissue plasminogen activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1 signaling pathway.

Journal: Molecular neurodegeneration20110101

Title: Inhibition of RhoA GTPase and the subsequent activation of PTP1B protects cultured hippocampal neurons against amyloid β toxicity.

Journal: Molecular neurodegeneration20110101

Title: Identification of alternatively spliced Dab1 and Fyn isoforms in pig.

Journal: BMC neuroscience20110101

Title: Maternal genome-wide DNA methylation patterns and congenital heart defects.

Journal: PloS one20110101

Title: Profiling the HER3/PI3K pathway in breast tumors using proximity-directed assays identifies correlations between protein complexes and phosphoproteins.

Journal: PloS one20110101

Title: A novel soluble immune-type receptor (SITR) in teleost fish: carp SITR is involved in the nitric oxide-mediated response to a protozoan parasite.

Journal: PloS one20110101

Title: Regulation of brown fat adipogenesis by protein tyrosine phosphatase 1B.

Journal: PloS one20110101

Title: Epidermal growth factor receptor mutation in combination with expression of MIG6 alters gefitinib sensitivity.

Journal: BMC systems biology20110101

Title: Interplay between kinase domain autophosphorylation and F-actin binding domain in regulating imatinib sensitivity and nuclear import of BCR-ABL.

Journal: PloS one20110101

Title: Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation.

Journal: PloS one20110101

Title: The RACK1 signaling scaffold protein selectively interacts with Yersinia pseudotuberculosis virulence function.

Journal: PloS one20110101

Title: Two TPX2-dependent switches control the activity of Aurora A.

Journal: PloS one20110101

Title: Jak2 is a negative regulator of ubiquitin-dependent endocytosis of the growth hormone receptor.

Journal: PloS one20110101

Title: Changes in expression of VE-cadherin and MMPs in endothelial cells: Implications for angiogenesis.

Journal: Vascular cell20110101

Title: Biosynthesis of Silver Nanoparticles from Desmodium triflorum: A Novel Approach Towards Weed Utilization.

Journal: Biotechnology research international20110101

Title: A Boolean-based systems biology approach to predict novel genes associated with cancer: Application to colorectal cancer.

Journal: BMC systems biology20110101

Title: δ-Tocotrienol and quercetin reduce serum levels of nitric oxide and lipid parameters in female chickens.

Journal: Lipids in health and disease20110101

Title: An unexpected role for the clock protein timeless in developmental apoptosis.

Journal: PloS one20110101

Title: Exploring the evolutionary relationship of insulin receptor substrate family using computational biology.

Journal: PloS one20110101

Title: Sprouty2 and Spred1-2 proteins inhibit the activation of the ERK pathway elicited by cyclopentenone prostanoids.

Journal: PloS one20110101

Title: Functional characterization of human cancer-derived TRKB mutations.

Journal: PloS one20110101

Title: Difluoromethylornithine is a novel inhibitor of Helicobacter pylori growth, CagA translocation, and interleukin-8 induction.

Journal: PloS one20110101

Title: Changes in gene expression and cellular architecture in an ovarian cancer progression model.

Journal: PloS one20110101

Title: Specific oncogenic activity of the Src-family tyrosine kinase c-Yes in colon carcinoma cells.

Journal: PloS one20110101

Title: EGFR Signaling in Colorectal Carcinoma.

Journal: Pathology research international20110101

Title: A functional polymorphism in B and T lymphocyte attenuator is associated with susceptibility to rheumatoid arthritis.

Journal: Clinical & developmental immunology20110101

Title: A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion.

Journal: PloS one20110101

Title: TACE/ADAM-17 phosphorylation by PKC-epsilon mediates premalignant changes in tobacco smoke-exposed lung cells.

Journal: PloS one20110101

Title: Diverse requirements for SRC-family tyrosine kinases distinguish chlamydial species.

Journal: mBio20110101

Title: Oncogene activation induces metabolic transformation resulting in insulin-independence in human breast cancer cells.

Journal: PloS one20110101

Title: Tyrosine phosphorylation profiling in FGF-2 stimulated human embryonic stem cells.

Journal: PloS one20110101

Title: A practical guide for the setup of a 1H-31P-13C double cross-polarization (DCP) experiment.

Journal: Solid state nuclear magnetic resonance20110101

Title: Post-translational modification biology of glutamate receptors and drug addiction.

Journal: Frontiers in neuroanatomy20110101

Title: Numb protects renal proximal tubular cells from puromycin aminonucleoside-induced apoptosis through inhibiting Notch signaling pathway.

Journal: International journal of biological sciences20110101

Title: Unexpected long-term protection of adult offspring born to high-fat fed dams against obesity induced by a sucrose-rich diet.

Journal: PloS one20110101

Title: The alternative splice variant of protein tyrosine kinase 6 negatively regulates growth and enhances PTK6-mediated inhibition of β-catenin.

Journal: PloS one20110101

Title: Complex interactions between GSK3 and aPKC in Drosophila embryonic epithelial morphogenesis.

Journal: PloS one20110101

Title: A STAT3-decoy oligonucleotide induces cell death in a human colorectal carcinoma cell line by blocking nuclear transfer of STAT3 and STAT3-bound NF-κB.

Journal: BMC cell biology20110101

Title: Phylogenetic analysis of kindlins suggests subfunctionalization of an ancestral unduplicated kindlin into three paralogs in vertebrates.

Journal: Evolutionary bioinformatics online20110101

Title: High-fat diet feeding alters metabolic response to fasting/non fasting conditions. Effect on caveolin expression and insulin signalling.

Journal: Lipids in health and disease20110101

Title: Cbl enforces Vav1 dependence and a restricted pathway of T cell development.

Journal: PloS one20110101

Title: Quantitative assays for the measurement of HER1-HER2 heterodimerization and phosphorylation in cell lines and breast tumors: applications for diagnostics and targeted drug mechanism of action.

Journal: Breast cancer research : BCR20110101

Title: Transcriptional activation of the Axl and PDGFR-α by c-Met through a ras- and Src-independent mechanism in human bladder cancer.

Journal: BMC cancer20110101

Title: Host plant effects on alkaline phosphatase activity in the whiteflies, Bemisia tabaci Biotype B and Trialeurodes vaporariorum.

Journal: Journal of insect science (Online)20110101

Title: Proline-rich tyrosine kinase 2 (Pyk2) promotes cell motility of hepatocellular carcinoma through induction of epithelial to mesenchymal transition.

Journal: PloS one20110101

Title: Vascular endothelial growth factor receptor-2 couples cyclo-oxygenase-2 with pro-angiogenic actions of leptin on human endothelial cells.

Journal: PloS one20110101

Title: Analysis of Jak2 catalytic function by peptide microarrays: the role of the JH2 domain and V617F mutation.

Journal: PloS one20110101

Title: Identification of receptor tyrosine kinase, discoidin domain receptor 1 (DDR1), as a potential biomarker for serous ovarian cancer.

Journal: International journal of molecular sciences20110101

Title: PTB domain-directed substrate targeting in a tyrosine kinase from the unicellular choanoflagellate Monosiga brevicollis.

Journal: PloS one20110101

Title: Simultaneous siRNA targeting of Src and downstream signaling molecules inhibit tumor formation and metastasis of a human model breast cancer cell line.

Journal: PloS one20110101

Title: Dual specificity phosphatase 1 regulates human inducible nitric oxide synthase expression by p38 MAP kinase.

Journal: Mediators of inflammation20110101

Title: Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4.

Journal: BMC biochemistry20110101

Title: Survey of activated FLT3 signaling in leukemia.

Journal: PloS one20110101

Title: The structural features of Trask that mediate its anti-adhesive functions.

Journal: PloS one20110101

Title: Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection.

Journal: Journal of biomedical science20110101

Title: Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.

Journal: PloS one20110101

Title: Role of surface chemistry in protein remodeling at the cell-material interface.

Journal: PloS one20110101

Title: Induction of TLR-2 and TLR-5 expression by Helicobacter pylori switches cagPAI-dependent signalling leading to the secretion of IL-8 and TNF-α.

Journal: PloS one20110101

Title: A functional nuclear epidermal growth factor receptor, SRC and Stat3 heteromeric complex in pancreatic cancer cells.

Journal: PloS one20110101

Title: Identification of phosphoproteins as possible differentiation markers in all-trans-retinoic acid-treated neuroblastoma cells.

Journal: PloS one20110101

Title: Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274.

Journal: Journal of translational medicine20110101

Title: Insulin resistance in non-obese subjects is associated with activation of the JNK pathway and impaired insulin signaling in skeletal muscle.

Journal: PloS one20110101

Title: Possible roles of ectophosphatases in host-parasite interactions.

Journal: Journal of parasitology research20110101

Title: Genistein increases epidermal growth factor receptor signaling and promotes tumor progression in advanced human prostate cancer.

Journal: PloS one20110101

Title: Mechanism of PhosphoThreonine/Serine Recognition and Specificity for Modular Domains from All-atom Molecular Dynamics.

Journal: BMC biophysics20110101

Title: Adaptor protein Shc acts as an immune-regulator for the LPS-stimulated maturation of bone marrow-derived dendritic cells.

Journal: BMC immunology20110101

Title: Ribosomal protein S6 kinase (RSK)-2 as a central effector molecule in RON receptor tyrosine kinase mediated epithelial to mesenchymal transition induced by macrophage-stimulating protein.

Journal: Molecular cancer20110101

Title: A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample.

Journal: PloS one20110101

Title: Dynamics of the STAT3 transcription factor: nuclear import dependent on Ran and importin-β1.

Journal: PloS one20110101

Title: P130Cas attenuates epidermal growth factor (EGF) receptor internalization by modulating EGF-triggered dynamin phosphorylation.

Journal: PloS one20110101

Title: Deconstructing GSK-3: The Fine Regulation of Its Activity.

Journal: International journal of Alzheimer's disease20110101

Title: Clinical and technical phosphoproteomic research.

Journal: Proteome science20110101

Title: Receptor tyrosine kinases in kidney development.

Journal: Journal of signal transduction20110101

Title: The Dynamical Systems Properties of the HOG Signaling Cascade.

Journal: Journal of signal transduction20110101

Title: Parasite mitogen-activated protein kinases as drug discovery targets to treat human protozoan pathogens.

Journal: Journal of signal transduction20110101

Title: Tyrosine Phosphorylation in the C-Terminal Nuclear Localization and Retention Signal (C-NLS) of the EWS Protein.

Journal: Sarcoma20110101

Title: BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cells.

Journal: PloS one20110101

Title: PLCβ1-SHP-2 complex, PLCβ1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling?

Journal: Journal of biomedical science20110101

Title: Antidepressant drugs transactivate TrkB neurotrophin receptors in the adult rodent brain independently of BDNF and monoamine transporter blockade.

Journal: PloS one20110101

Title: Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer.

Journal: PloS one20110101

Title: Negative regulation of interferon-β gene expression during acute and persistent virus infections.

Journal: PloS one20110101

Title: Sunitinib inhibits lymphatic endothelial cell functions and lymph node metastasis in a breast cancer model through inhibition of vascular endothelial growth factor receptor 3.

Journal: Breast cancer research : BCR20110101

Title: LyGDI, a novel SHIP-interacting protein, is a negative regulator of FcγR-mediated phagocytosis.

Journal: PloS one20110101

Title: Murine missing in metastasis (MIM) mediates cell polarity and regulates the motility response to growth factors.

Journal: PloS one20110101

Title: Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages.

Journal: Retrovirology20110101

Title: Anchored design of protein-protein interfaces.

Journal: PloS one20110101

Title: PlantPhos: using maximal dependence decomposition to identify plant phosphorylation sites with substrate site specificity.

Journal: BMC bioinformatics20110101

Title: Analysis of EGFR signaling pathway in nasopharyngeal carcinoma cells by quantitative phosphoproteomics.

Journal: Proteome science20110101

Title: The complete genome sequence and genetic analysis of ΦCA82 a novel uncultured microphage from the turkey gastrointestinal system.

Journal: Virology journal20110101

Title: Phosphoproteins regulated by heat stress in rice leaves.

Journal: Proteome science20110101

Title: Targeting insulin-like growth factor axis in hepatocellular carcinoma.

Journal: Journal of hematology & oncology20110101

Title: Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism.

Journal: PloS one20110101

Title: Radioactive phosphorylation of alcohols to monitor biocatalytic Diels-Alder reactions.

Journal: PloS one20110101

Title: Proteomic analysis of pathways involved in estrogen-induced growth and apoptosis of breast cancer cells.

Journal: PloS one20110101

Title: Phasic phosphorylation of caldesmon and ERK 1/2 during contractions in human myometrium.

Journal: PloS one20110101

Title: GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness.

Journal: PloS one20110101

Title: Amitriptyline-mediated cognitive enhancement in aged 3×Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity.

Journal: PloS one20110101

Title: Phosphoproteomic profiling of in vivo signaling in liver by the mammalian target of rapamycin complex 1 (mTORC1).

Journal: PloS one20110101

Title: Overexpression of SIRT1 in mouse forebrain impairs lipid/glucose metabolism and motor function.

Journal: PloS one20110101

Title: Control of host cell phosphorylation by legionella pneumophila.

Journal: Frontiers in microbiology20110101

Title: Insulin receptor substrate 2 expression and involvement in neuronal insulin resistance in diabetic neuropathy.

Journal: Experimental diabetes research20110101

Title: Identification of novel therapeutic targets in microdissected clear cell ovarian cancers.

Journal: PloS one20110101

Title: Determinants for Substrate Specificity of Protein Phosphatase 2A.

Journal: Enzyme research20110101

Title: Solution structure of tensin2 SH2 domain and its phosphotyrosine-independent interaction with DLC-1.

Journal: PloS one20110101

Title: A novel role of protein tyrosine kinase2 in mediating chloride secretion in human airway epithelial cells.

Journal: PloS one20110101

Title: Association of acid phosphatase locus 1*C allele with the risk of cardiovascular events in rheumatoid arthritis patients.

Journal: Arthritis research & therapy20110101

Title: Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range.

Journal: Molecular systems biology20110101

Title: Regulation and function of syk tyrosine kinase in mast cell signaling and beyond.

Journal: Journal of signal transduction20110101

Title: Functional Diversity of the Schistosoma mansoni Tyrosine Kinases.

Journal: Journal of signal transduction20110101

Title: Regulation of SRC family kinases in human cancers.

Journal: Journal of signal transduction20110101

Title: Tyrosine phosphorylation-mediated signaling pathways in dictyostelium.

Journal: Journal of signal transduction20110101

Title: USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response.

Journal: PloS one20110101

Title: E7080, a multi-targeted tyrosine kinase inhibitor suppresses tumor cell migration and invasion.

Journal: BMC cancer20110101

Title: Myricetin Ameliorates Defective Post-Receptor Insulin Signaling via β-Endorphin Signaling in the Skeletal Muscles of Fructose-Fed Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM20110101

Title: From the bench to bedside: biological and methodology considerations for the future of companion diagnostics in nonsmall cell lung cancer.

Journal: Pathology research international20110101

Title: The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology.

Journal: Genome biology20110101

Title: Administration of chinpi, a component of the herbal medicine ninjin-youei-to, reverses age-induced demyelination.

Journal: Evidence-based complementary and alternative medicine : eCAM20110101

Title: High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria.

Journal: PloS one20110101

Title: The hepatitis E virus ORF3 protein regulates the expression of liver-specific genes by modulating localization of hepatocyte nuclear factor 4.

Journal: PloS one20110101

Title: A Src-Tks5 pathway is required for neural crest cell migration during embryonic development.

Journal: PloS one20110101

Title: Protein Tyrosine Phosphatase SHP-2 (PTPN11) in Hematopoiesis and Leukemogenesis.

Journal: Journal of signal transduction20110101

Title: Tyrosine kinase inhibitor, genistein, reduces renal inflammation and injury in streptozotocin-induced diabetic mice.

Journal: Vascular pharmacology20110101

Title: The Role of BDNF/TrkB Signaling in Acute Amphetamine-Induced Locomotor Activity and Opioid Peptide Gene Expression in the Rat Dorsal Striatum.

Journal: Frontiers in systems neuroscience20110101

Title: Intracellular trafficking of the amyloid β-protein precursor (APP) regulated by novel function of X11-like.

Journal: PloS one20110101

Title: Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway.

Journal: PloS one20110101

Title: Molecular evolution of the LNX gene family.

Journal: BMC evolutionary biology20110101

Title: Redox-induced Src kinase and caveolin-1 signaling in TGF-β1-initiated SMAD2/3 activation and PAI-1 expression.

Journal: PloS one20110101

Title: Quantitative analysis of protein phosphorylations and interactions by multi-colour IP-FCM as an input for kinetic modelling of signalling networks.

Journal: PloS one20110101

Title: Highly efficient production of soluble proteins from insoluble inclusion bodies by a two-step-denaturing and refolding method.

Journal: PloS one20110101

Title: Characterization of Leishmania donovani MCM4: expression patterns and interaction with PCNA.

Journal: PloS one20110101

Title: Simulating EGFR-ERK signaling control by scaffold proteins KSR and MP1 reveals differential ligand-sensitivity co-regulated by Cbl-CIN85 and endophilin.

Journal: PloS one20110101

Title: Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes.

Journal: Arthritis research & therapy20110101

Title: Downregulation of TFPI in breast cancer cells induces tyrosine phosphorylation signaling and increases metastatic growth by stimulating cell motility.

Journal: BMC cancer20110101

Title: Evolutionary versatility of eukaryotic protein domains revealed by their bigram networks.

Journal: BMC evolutionary biology20110101

Title: PTPBR7 binding proteins in myelinating neurons of the mouse brain.

Journal: International journal of biological sciences20110101

Title: RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation.

Journal: PloS one20110101

Title: Evaluating experimental bias and completeness in comparative phosphoproteomics analysis.

Journal: PloS one20110101

Title: LIP expression is regulated by IGF-1R signaling and participates in suppression of anoikis.

Journal: Molecular cancer20110101

Title: The Role of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) in Cognition.

Journal: Frontiers in neuroanatomy20110101

Title: TC-PTP dephosphorylates the guanine nucleotide exchange factor C3G (RapGEF1) and negatively regulates differentiation of human neuroblastoma cells.

Journal: PloS one20110101

Title: Discovering and validating unknown phospho-sites from p38 and HuR protein kinases in vitro by Phosphoproteomic and Bioinformatic tools.

Journal: Journal of clinical bioinformatics20110101

Title: HIV-1 Nef induces proinflammatory state in macrophages through its acidic cluster domain: involvement of TNF alpha receptor associated factor 2.

Journal: PloS one20110101

Title: Spatial association of signaling proteins and F-actin effects on cluster assembly analyzed via photoactivation localization microscopy in T cells.

Journal: PloS one20110101

Title: Laforin, a dual specificity phosphatase involved in Lafora disease, is present mainly as monomeric form with full phosphatase activity.

Journal: PloS one20110101

Title: C-KIT signaling depends on microphthalmia-associated transcription factor for effects on cell proliferation.

Journal: PloS one20110101

Title: Structural and Functional Consequences Induced by Post-Translational Modifications in α-Defensins.

Journal: International journal of peptides20110101

Title: Protein kinases and phosphatases in the control of cell fate.

Journal: Enzyme research20110101

Title: SOD3 decreases ischemic injury derived apoptosis through phosphorylation of Erk1/2, Akt, and FoxO3a.

Journal: PloS one20110101

Title: Phosphoprotein associated with glycosphingolipid-enriched microdomains differentially modulates SRC kinase activity in brain maturation.

Journal: PloS one20110101

Title: A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death.

Journal: PloS one20110101

Title: Plasma and cellular fibronectin: distinct and independent functions during tissue repair.

Journal: Fibrogenesis & tissue repair20110101

Title: FRS2α is essential for the fibroblast growth factor to regulate the mTOR pathway and autophagy in mouse embryonic fibroblasts.

Journal: International journal of biological sciences20110101

Title: SITC/iSBTc Cancer Immunotherapy Biomarkers Resource Document: online resources and useful tools - a compass in the land of biomarker discovery.

Journal: Journal of translational medicine20110101

Title: EphA4 blockers promote axonal regeneration and functional recovery following spinal cord injury in mice.

Journal: PloS one20110101

Title: Modulation of catalytic activity in multi-domain protein tyrosine phosphatases.

Journal: PloS one20110101

Title: The long noncoding RNA Six3OS acts in trans to regulate retinal development by modulating Six3 activity.

Journal: Neural development20110101

Title: Abolished adherence alters signaling pathways in phorbol ester-induced human U937 cells.

Journal: Cell communication and signaling : CCS20110101

Title: erbB3 recruitment of insulin receptor substrate 1 modulates insulin-like growth factor receptor signalling in oestrogen receptor-positive breast cancer cell lines.

Journal: Breast cancer research : BCR20110101

Title: Decreased expression of dual-specificity phosphatase 9 is associated with poor prognosis in clear cell renal cell carcinoma.

Journal: BMC cancer20110101

Title: Transcriptome profiling of immune responses to cardiomyopathy syndrome (CMS) in Atlantic salmon.

Journal: BMC genomics20110101

Title: The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR.

Journal: PloS one20110101

Title: The functioning of the Drosophila CPEB protein Orb is regulated by phosphorylation and requires casein kinase 2 activity.

Journal: PloS one20110101

Title: Quantitative phosphoproteomics of CXCL12 (SDF-1) signaling.

Journal: PloS one20110101

Title: Ankyrin repeat and SOCS box containing protein 4 (Asb-4) colocalizes with insulin receptor substrate 4 (IRS4) in the hypothalamic neurons and mediates IRS4 degradation.

Journal: BMC neuroscience20110101

Title: Effects of nutritional cues on the duration of the winter anovulatory phase and on associated hormone levels in adult female Welsh pony horses (Equus caballus).

Journal: Reproductive biology and endocrinology : RB&E20110101

Title: Comparative transcriptome sequencing of germline and somatic tissues of the Ascaris suum gonad.

Journal: BMC genomics20110101

Title: Targeting HSP90 in ovarian cancers with multiple receptor tyrosine kinase coactivation.

Journal: Molecular cancer20110101

Title: Profiling the Trypanosoma cruzi phosphoproteome.

Journal: PloS one20110101

Title: Technical phosphoproteomic and bioinformatic tools useful in cancer research.

Journal: Journal of clinical bioinformatics20110101

Title: Prenatal cocaine exposure increases synaptic localization of a neuronal RasGEF, GRASP-1 via hyperphosphorylation of AMPAR anchoring protein, GRIP.

Journal: PloS one20110101

Title: The SOCS2 ubiquitin ligase complex regulates growth hormone receptor levels.

Journal: PloS one20110101

Title: Nano-stenciled RGD-gold patterns that inhibit focal contact maturation induce lamellipodia formation in fibroblasts.

Journal: PloS one20110101

Title: Constitutive expression of insulin receptor substrate (IRS)-1 inhibits myogenic differentiation through nuclear exclusion of Foxo1 in L6 myoblasts.

Journal: PloS one20110101

Title: Nck2 promotes human melanoma cell proliferation, migration and invasion in vitro and primary melanoma-derived tumor growth in vivo.

Journal: BMC cancer20110101

Title: Gene expression of human lung cancer cell line CL1-5 in response to a direct current electric field.

Journal: PloS one20110101

Title: Syk protein tyrosine kinase involves PECAM-1 signaling through tandem immunotyrosine inhibitory motifs in human THP-1 macrophages.

Journal: Cellular immunology20110101

Title: DomPep--a general method for predicting modular domain-mediated protein-protein interactions.

Journal: PloS one20110101

Title: Modulation of GSK-3 as a Therapeutic Strategy on Tau Pathologies.

Journal: Frontiers in molecular neuroscience20110101

Title: Structure-activity relationship of halophenols as a new class of protein tyrosine kinase inhibitors.

Journal: International journal of molecular sciences20110101

Title: Association of reactive oxygen species-mediated signal transduction with in vitro apoptosis sensitivity in chronic lymphocytic leukemia B cells.

Journal: PloS one20110101

Title: Signal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer.

Journal: Breast cancer research : BCR20110101

Title: Critical amino acid residues in proteins: a BioMart integration of Reactome protein annotations with PRIDE mass spectrometry data and COSMIC somatic mutations.

Journal: Database : the journal of biological databases and curation20110101

Title: The role of atypical protein kinase C in CSF-1-dependent Erk activation and proliferation in myeloid progenitors and macrophages.

Journal: PloS one20110101

Title: The adaptor protein SH2B3 (Lnk) negatively regulates neurite outgrowth of PC12 cells and cortical neurons.

Journal: PloS one20110101

Title: β-Adrenergic receptor-PI3K signaling crosstalk in mouse heart: elucidation of immediate downstream signaling cascades.

Journal: PloS one20110101

Title: Hypoxic pulmonary hypertension in mice with constitutively active platelet-derived growth factor receptor-β.

Journal: Pulmonary circulation20110101

Title: Inferring pleiotropy by network analysis: linked diseases in the human PPI network.

Journal: BMC systems biology20110101

Title: The secret life of kinases: functions beyond catalysis.

Journal: Cell communication and signaling : CCS20110101

Title: The synthetic tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis.

Journal: Critical care (London, England)20110101

Title: BID-F1 and BID-F2 domains of Bartonella henselae effector protein BepF trigger together with BepC the formation of invasome structures.

Journal: PloS one20110101

Title: Mechanism of acetylcholine receptor cluster formation induced by DC electric field.

Journal: PloS one20110101

Title: Methanosarcina acetivorans C2A topoisomerase IIIα, an archaeal enzyme with promiscuity in divalent cation dependence.

Journal: PloS one20110101

Title: Palmitate-activated macrophages confer insulin resistance to muscle cells by a mechanism involving protein kinase C θ and ε.

Journal: PloS one20110101

Title: Erythropoietin enhances nerve repair in anti-ganglioside antibody-mediated models of immune neuropathy.

Journal: PloS one20110101

Title: Crystal structure of thrombin in complex with S-variegin: insights of a novel mechanism of inhibition and design of tunable thrombin inhibitors.

Journal: PloS one20110101

Title: Molecular markers to characterize the hermaphroditic reproductive system of the planarian Schmidtea mediterranea.

Journal: BMC developmental biology20110101

Title: ALK and NSCLC: Targeted therapy with ALK inhibitors.

Journal: F1000 medicine reports20110101

Title: Role and expression of FRS2 and FRS3 in prostate cancer.

Journal: BMC cancer20110101

Title: Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility.

Journal: BMC cell biology20110101

Title: Biochemical and computational analysis of LNX1 interacting proteins.

Journal: PloS one20110101

Title: DNA damage stress and inhibition of Jak2-V617F cause its degradation and synergistically induce apoptosis through activation of GSK3β.

Journal: PloS one20110101

Title: Evasion of Host Defence by Leishmania donovani: Subversion of Signaling Pathways.

Journal: Molecular biology international20110101

Title: Use of antimony in the treatment of leishmaniasis: current status and future directions.

Journal: Molecular biology international20110101

Title: Activation of neutrophils by nanoparticles.

Journal: TheScientificWorldJournal20110101

Title: Suppressor of cytokine signalling-6 promotes neurite outgrowth via JAK2/STAT5-mediated signalling pathway, involving negative feedback inhibition.

Journal: PloS one20110101

Title: Bidirectional remodeling of β1-integrin adhesions during chemotropic regulation of nerve growth.

Journal: BMC biology20110101

Title: Insulin receptor-mediated signaling via phospholipase C-γ regulates growth and differentiation in Drosophila.

Journal: PloS one20110101

Title: Mutations in the catalytic loop HRD motif alter the activity and function of Drosophila Src64.

Journal: PloS one20110101

Title: Regulation of suppressors of cytokine signaling as a therapeutic approach in autoimmune diseases, with an emphasis on multiple sclerosis.

Journal: Journal of signal transduction20110101

Title: Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II.

Journal: PloS one20110101

Title: Stat3 mediates expression of autotaxin in breast cancer.

Journal: PloS one20110101

Title: Spectrum of oncogenic driver mutations in lung adenocarcinomas from East Asian never smokers.

Journal: PloS one20110101

Title: MUC1-C oncoprotein regulates glycolysis and pyruvate kinase M2 activity in cancer cells.

Journal: PloS one20110101

Title: Regulation of hTERT by BCR-ABL at multiple levels in K562 cells.

Journal: BMC cancer20110101

Title: The SH2 domain-containing proteins in 21 species establish the provenance and scope of phosphotyrosine signaling in eukaryotes.

Journal: Science signaling20110101

Title: Crizotinib: a novel and first-in-class multitargeted tyrosine kinase inhibitor for the treatment of anaplastic lymphoma kinase rearranged non-small cell lung cancer and beyond.

Journal: Drug design, development and therapy20110101

Title: Disabled-1 alternative splicing in human fetal retina and neural tumors.

Journal: PloS one20110101

Title: Tyrosine phosphorylation of Rac1: a role in regulation of cell spreading.

Journal: PloS one20110101

Title: Inhibition of interferon induction and action by the nairovirus Nairobi sheep disease virus/Ganjam virus.

Journal: PloS one20110101

Title: The tyrosine kinase inhibitor dasatinib induces a marked adipogenic differentiation of human multipotent mesenchymal stromal cells.

Journal: PloS one20110101

Title: Development of derivatives of 3, 3'-diindolylmethane as potent Leishmania donovani bi-subunit topoisomerase IB poisons.

Journal: PloS one20110101

Title: Phosphorylation of Akt and ERK1/2 is required for VEGF-A/VEGFR2-induced proliferation and migration of lymphatic endothelium.

Journal: PloS one20110101

Title: Continuous requirement of ErbB2 kinase activity for loss of cell polarity and lumen formation in a novel ErbB2/Neu-driven murine cell line model of metastatic breast cancer.

Journal: Journal of carcinogenesis20110101

Title: PEGylation potentiates the effectiveness of an antagonistic peptide that targets the EphB4 receptor with nanomolar affinity.

Journal: PloS one20110101

Title: Nephrin regulates lamellipodia formation by assembling a protein complex that includes Ship2, filamin and lamellipodin.

Journal: PloS one20110101

Title: Systems biology modeling reveals a possible mechanism of the tumor cell death upon oncogene inactivation in EGFR addicted cancers.

Journal: PloS one20110101

Title: Cyclic stress at mHz frequencies aligns fibroblasts in direction of zero strain.

Journal: PloS one20110101

Title: Curative effect of 18β-glycyrrhetinic acid in experimental visceral leishmaniasis depends on phosphatase-dependent modulation of cellular MAP kinases.

Journal: PloS one20110101

Title: Polarized endocytosis of the keratinocyte growth factor receptor in migrating cells: role of SRC-signaling and cortactin.

Journal: PloS one20110101

Title: Fish Suppressors of Cytokine Signaling (SOCS): Gene Discovery, Modulation of Expression and Function.

Journal: Journal of signal transduction20110101

Title: Tyrosine kinase chromosomal translocations mediate distinct and overlapping gene regulation events.

Journal: BMC cancer20110101

Title: Mechanism and regulation of nucleocytoplasmic trafficking of smad.

Journal: Cell & bioscience20110101

Title: A cell-based protein-protein interaction method using a permuted luciferase reporter.

Journal: Current chemical genomics20110101

Title: A crucial role of activin A-mediated growth hormone suppression in mouse and human heart failure.

Journal: PloS one20110101

Title: Deep-sequencing analysis of the mouse transcriptome response to infection with Brucella melitensis strains of differing virulence.

Journal: PloS one20110101

Title: Lapatinib induces autophagy, apoptosis and megakaryocytic differentiation in chronic myelogenous leukemia K562 cells.

Journal: PloS one20110101

Title: Role of palladin phosphorylation by extracellular signal-regulated kinase in cell migration.

Journal: PloS one20110101

Title: Novel insights into the role of caveolin-2 in cell- and tissue-specific signaling and function.

Journal: Biochemistry research international20110101

Title: The Shc family protein adaptor, Rai, negatively regulates T cell antigen receptor signaling by inhibiting ZAP-70 recruitment and activation.

Journal: PloS one20110101

Title: Fast disintegrating tablets: Opportunity in drug delivery system.

Journal: Journal of advanced pharmaceutical technology & research20110101

Title: Advances in carcinogenic metal toxicity and potential molecular markers.

Journal: International journal of molecular sciences20110101

Title: Phosphoproteomics-based systems analysis of signal transduction networks.

Journal: Frontiers in physiology20110101

Title: Tuning the orchestra: transcriptional pathways controlling axon regeneration.

Journal: Frontiers in molecular neuroscience20110101

Title: Signal protein-derived peptides as functional probes and regulators of intracellular signaling.

Journal: Journal of amino acids20110101

Title: Mechanisms of brain aging regulation by insulin: implications for neurodegeneration in late-onset Alzheimer's disease.

Journal: ISRN neurology20110101

Title: Initiation of TCR phosphorylation and signal transduction.

Journal: Frontiers in immunology20110101

Title: Adiponectin action: a combination of endocrine and autocrine/paracrine effects.

Journal: Frontiers in endocrinology20110101

Title: Landmarks in insulin research.

Journal: Frontiers in endocrinology20110101

Title: The insulin receptor: a new target for cancer therapy.

Journal: Frontiers in endocrinology20110101

Title: PI3K Pathway in NSCLC.

Journal: Frontiers in oncology20110101

Title: Allosteric regulation of glycogen synthase kinase 3β: a theoretical study.

Journal: Biochemistry20101228

Title: A protected l-bromophosphonomethylphenylalanine amino acid derivative (BrPmp) for synthesis of irreversible protein tyrosine phosphatase inhibitors.

Journal: Bioorganic & medicinal chemistry20101215

Title: CEACAM1: a key regulator of vascular permeability.

Journal: Journal of cell science20101215

Title: Silencing of the PP2A catalytic subunit causes HER-2/neu positive breast cancer cells to undergo apoptosis.

Journal: Experimental cell research20101210

Title: Is there an association with phosphorylation and dephosphorylation of Src kinase at tyrosine 530 and breast cancer patient disease-specific survival.

Journal: British journal of cancer20101207

Title: Identification of tyrosine phosphoproteins in signaling pathway triggered TGF-a by using functional proteomics technology.

Journal: Medical oncology (Northwood, London, England)20101201

Title: Phosphate ester hydrolysis of biologically relevant molecules by cerium oxide nanoparticles.

Journal: Nanomedicine : nanotechnology, biology, and medicine20101201

Title: Comprehensive analysis of phosphorylation sites in Tensin1 reveals regulation by p38MAPK.

Journal: Molecular & cellular proteomics : MCP20101201

Title: Pseudokinases-remnants of evolution or key allosteric regulators?

Journal: Current opinion in structural biology20101201

Title: AZ960, a novel Jak2 inhibitor, induces growth arrest and apoptosis in adult T-cell leukemia cells.

Journal: Molecular cancer therapeutics20101201

Title: Interaction of c-Cbl with myosin IIA regulates Bleb associated macropinocytosis of Kaposi's sarcoma-associated herpesvirus.

Journal: PLoS pathogens20101201

Title: Modulation of protein tyrosine phosphorylation in gastric mucosa during re-epithelization processes.

Journal: World journal of biological chemistry20101126

Title: Rate enhancement of an interfacial biochemical reaction through localization of substrate and enzyme by an adaptor domain.

Journal: The journal of physical chemistry. B20101125

Title: The streptococcal collagen-binding protein CNE specifically interferes with alphaVbeta3-mediated cellular interactions with triple helical collagen.

Journal: The Journal of biological chemistry20101112

Title: Integrin {beta}3 phosphorylation dictates its complex with the Shc phosphotyrosine-binding (PTB) domain.

Journal: The Journal of biological chemistry20101105

Title: Expression of oncogenic K-ras and loss of Smad4 cooperate to induce the expression of EGFR and to promote invasion of immortalized human pancreas ductal cells.

Journal: International journal of cancer20101101

Title: Protein kinase substrate profiling with a high-density peptide microarray.

Journal: Combinatorial chemistry & high throughput screening20101101

Title: SH2 domains recognize contextual peptide sequence information to determine selectivity.

Journal: Molecular & cellular proteomics : MCP20101101

Title: EphA3 functions are regulated by collaborating phosphotyrosine residues.

Journal: Cell research20101101

Title: A cell-based screen for inhibitors of protein folding and degradation.

Journal: Cell stress & chaperones20101101

Title: Platelet endothelial cell adhesion molecule-1 regulates collagen-stimulated platelet function by modulating the association of phosphatidylinositol 3-kinase with Grb-2-associated binding protein-1 and linker for activation of T cells.

Journal: Journal of thrombosis and haemostasis : JTH20101101

Title: Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia.

Journal: Journal of cell science20101101

Title: The Caenorhabditis elegans Kinesin-3 motor UNC-104/KIF1A is degraded upon loss of specific binding to cargo.

Journal: PLoS genetics20101101

Title: Tyrosine phosphorylation enrichment and subsequent analysis by MALDI-TOF/TOF MS/MS and LC-ESI-IT-MS/MS.

Journal: Current protocols in protein science20101101

Title: Fcγ receptor I alpha chain (CD64) expression in macrophages is critical for the onset of meningitis by Escherichia coli K1.

Journal: PLoS pathogens20101101

Title: A computational approach to analyze the mechanism of action of the kinase inhibitor bafetinib.

Journal: PLoS computational biology20101101

Title: Functional phosphoproteomic analysis reveals cold-shock domain protein A to be a Bcr-Abl effector-regulating proliferation and transformation in chronic myeloid leukemia.

Journal: Cell death & disease20101101

Title: Clinical, Molecular, and Genetic Characteristics of PAPA Syndrome: A Review.

Journal: Current genomics20101101

Title: Lipid rafts and redox regulation of cellular signaling in cholesterol induced atherosclerosis.

Journal: Current cardiology reviews20101101

Title: Detection of tyrosine phosphorylated proteins by combination of immunoaffinity enrichment, two-dimensional difference gel electrophoresis and fluorescent Western blotting.

Journal: Biochemical and biophysical research communications20101029

Title: Mycobacterium tuberculosis tyrosine phosphatase A (PtpA) activity is modulated by S-nitrosylation.

Journal: Chemical communications (Cambridge, England)20101028

Title: Early response to ErbB2 over-expression in polarized Caco-2 cells involves partial segregation from ErbB3 by relocalization to the apical surface and initiation of survival signaling.

Journal: Journal of cellular biochemistry20101015

Title: The Structure of the talin head reveals a novel extended conformation of the FERM domain.

Journal: Structure (London, England : 1993)20101013

Title: Evaluation of erythrocyte band 3 phosphotyrosine level, glutathione content, CA-125, and human epididymal secretory protein E4 as combined parameters in endometriosis.

Journal: Fertility and sterility20101001

Title: Trypanosomatid protein phosphatases.

Journal: Molecular and biochemical parasitology20101001

Title: Infrequent methylation of the DUSP6 phosphatase in endometrial cancer.

Journal: Gynecologic oncology20101001

Title: Disabled-2 is required for mesoderm differentiation of murine embryonic stem cells.

Journal: Journal of cellular physiology20101001

Title: CLE14/CLE20 peptides may interact with CLAVATA2/CORYNE receptor-like kinases to irreversibly inhibit cell division in the root meristem of Arabidopsis.

Journal: Planta20101001

Title: Wnt5a/Ror2-induced upregulation of xPAPC requires xShcA.

Journal: Biochemical and biophysical research communications20101001

Title: Analysis of changes in tyrosine and serine phosphorylation of red cell membrane proteins induced by P. falciparum growth.

Journal: Proteomics20101001

Title: A dynamic immunological synapse mediates homeostatic TCR-dependent and -independent signaling.

Journal: European journal of immunology20101001

Title: Integrated data management and validation platform for phosphorylated tandem mass spectrometry data.

Journal: Proteomics20101001

Title: Binding of flexible and constrained ligands to the Grb2 SH2 domain: structural effects of ligand preorganization.

Journal: Acta crystallographica. Section D, Biological crystallography20101001

Title: Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63.

Journal: PLoS pathogens20101001

Title: Genotoxicity and cytotoxicity of zinc oxide and titanium dioxide in HEp-2 cells.

Journal: Nanomedicine (London, England)20101001

Title: Phosphotyrosine signaling: evolving a new cellular communication system.

Journal: Cell20100903

Title: DUSP26 negatively affects the proliferation of epithelial cells, an effect not mediated by dephosphorylation of MAPKs.

Journal: Biochimica et biophysica acta20100901

Title: The human megakaryocytic cell line UT-7/TPO expresses functional platelet agonist signals mediated through GPVI and thromboxane receptor.

Journal: Cell biology international20100901

Title: The structure of invadopodia in a complex 3D environment.

Journal: European journal of cell biology20100901

Title: Elimination of negative feedback control mechanisms along the insulin signaling pathway improves beta-cell function under stress.

Journal: Diabetes20100901

Title: Role of glycerol-3-phosphate dehydrogenase 2 in mouse sperm capacitation.

Journal: Molecular reproduction and development20100901

Title: Somatostatin receptor activation (sst(1) -sst(5) ) differentially influences human retinal pigment epithelium cell viability.

Journal: Acta ophthalmologica20100901

Title: Prophossi: automating expert validation of phosphopeptide-spectrum matches from tandem mass spectrometry.

Journal: Bioinformatics (Oxford, England)20100901

Title: Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development.

Journal: Genesis (New York, N.Y. : 2000)20100901

Title: Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation.

Journal: Journal of immunology (Baltimore, Md. : 1950)20100901

Title: Lineage-specific expansion of DNA-binding transcription factor families.

Journal: Trends in genetics : TIG20100901

Title: The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis.

Journal: Angiogenesis20100901

Title: Constraining binding hot spots: NMR and molecular dynamics simulations provide a structural explanation for enthalpy-entropy compensation in SH2-ligand binding.

Journal: Journal of the American Chemical Society20100818

Title: Mechanism of tyrosine phosphorylation of procaspase-9 and Apaf-1 in cytosolic fractions of the cerebral cortex of newborn piglets during hypoxia.

Journal: Neuroscience letters20100809

Title: Identification of phosphorylation-dependent interaction partners of the adapter protein ADAP using quantitative mass spectrometry: SILAC vs (18)O-labeling.

Journal: Journal of proteome research20100806

Title: An X11alpha/FSBP complex represses transcription of the GSK3beta gene promoter.

Journal: Neuroreport20100804

Title: Syndecan- and integrin-binding peptides synergistically accelerate cell adhesion.

Journal: FEBS letters20100804

Title: Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.

Journal: FEBS letters20100804

Title: Involvement of receptor tyrosine phosphatase DEP-1 mediated PI3K-cofilin signaling pathway in sorafenib-induced cytoskeletal rearrangement in hepatoma cells.

Journal: Journal of cellular physiology20100801

Title: Multiplex analysis of Src family kinase signaling by microbead suspension arrays.

Journal: Assay and drug development technologies20100801

Title: Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women.

Journal: Diabetes20100801

Title: Syntheses and activities of backbone-side chain cyclic octapeptide ligands with N-functionalized phosphotyrosine for the N-terminal SH2-domain of the protein tyrosine phosphatase SHP-1.

Journal: Journal of peptide science : an official publication of the European Peptide Society20100801

Title: Sorafenib activates CD95 and promotes autophagy and cell death via Src family kinases in gastrointestinal tumor cells.

Journal: Molecular cancer therapeutics20100801

Title: Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements.

Journal: PLoS biology20100801

Title: IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition.

Journal: PLoS biology20100801

Title: Investigation of mechanism of p38 MAPK activation in renal epithelial cell from distal tubules triggered by cardiotonic steroids.

Journal: Biochemistry. Biokhimiia20100801

Title: Estrogen receptor alpha phosphorylated at tyrosine 537 is associated with poor clinical outcome in breast cancer patients treated with tamoxifen.

Journal: Hormones & cancer20100801

Title: PTP1B targets the endosomal sorting machinery: dephosphorylation of regulatory sites on the endosomal sorting complex required for transport component STAM2.

Journal: The Journal of biological chemistry20100730

Title: Two novel Src homology 2 domain proteins interact to regulate dictyostelium gene expression during growth and early development.

Journal: The Journal of biological chemistry20100723

Title: A small fibronectin-mimicking protein from bacteria induces cell spreading and focal adhesion formation.

Journal: The Journal of biological chemistry20100723

Title: The Trypanosoma brucei life cycle switch TbPTP1 is structurally conserved and dephosphorylates the nucleolar protein NOPP44/46.

Journal: The Journal of biological chemistry20100716

Title: Ectodomain shedding of interleukin-2 receptor beta and generation of an intracellular functional fragment.

Journal: The Journal of biological chemistry20100716

Title: Vascular endothelial growth factors and vascular permeability.

Journal: Cardiovascular research20100715

Title: Laforin, the most common protein mutated in Lafora disease, regulates autophagy.

Journal: Human molecular genetics20100715

Title: Increased circulating cell signalling phosphoproteins in sera are useful for the detection of pancreatic cancer.

Journal: British journal of cancer20100713

Title: Neuromedin B receptors regulate EGF receptor tyrosine phosphorylation in lung cancer cells.

Journal: European journal of pharmacology20100710

Title: The cytoplasmic adaptor protein Dok7 activates the receptor tyrosine kinase MuSK via dimerization.

Journal: Molecular cell20100709

Title: Development of a two-part strategy to identify a therapeutic human bispecific antibody that inhibits IgE receptor signaling.

Journal: The Journal of biological chemistry20100702

Title: Synthetic strategies to a backbone-side chain cyclic SHP-1 N-SH2 ligand containing N-functionalized alkyl phosphotyrosine.

Journal: Protein and peptide letters20100701

Title: Elucidation of the signaling pathways that underpin capacitation-associated surface phosphotyrosine expression in mouse spermatozoa.

Journal: Journal of cellular physiology20100701

Title: Polychlorinated biphenyls disrupt intestinal integrity via NADPH oxidase-induced alterations of tight junction protein expression.

Journal: Environmental health perspectives20100701

Title: Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009.

Journal: Diabetologia20100701

Title: Proteomics study of oxidative stress and Src kinase inhibition in H9C2 cardiomyocytes: a cell model of heart ischemia-reperfusion injury and treatment.

Journal: Free radical biology & medicine20100701

Title: EZYprep LC-coupled MALDI-TOF/TOF MS: an improved matrix spray application for phosphopeptide characterisation.

Journal: Proteomics20100701

Title: NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH.

Journal: Chemical biology & drug design20100701

Title: Phosphotyrosine signaling analysis of site-specific mutations on EGFRvIII identifies determinants governing glioblastoma cell growth.

Journal: Molecular bioSystems20100701

Title: Thermodynamics of phosphotyrosine peptide-peptoid hybrids binding to the p56lck SH2 domain.

Journal: Journal of peptide science : an official publication of the European Peptide Society20100701

Title: Plasmodium falciparum adhesion on human brain microvascular endothelial cells involves transmigration-like cup formation and induces opening of intercellular junctions.

Journal: PLoS pathogens20100701

Title: Protein kinase C activation has distinct effects on the localization, phosphorylation and detergent solubility of the claudin protein family in tight and leaky epithelial cells.

Journal: The Journal of membrane biology20100701

Title: Src activates Abl to augment Robo1 expression in order to promote tumor cell migration.

Journal: Oncotarget20100701

Title: PEAK1, a novel kinase target in the fight against cancer.

Journal: Oncotarget20100701

Title: Phosphorylation of Puma modulates its apoptotic function by regulating protein stability.

Journal: Cell death & disease20100701

Title: Uncoupling of T cell receptor zeta chain function during the induction of anergy by the superantigen, staphylococcal enterotoxin A.

Journal: Toxins20100701

Title: Mutations in MUSK causing congenital myasthenic syndrome impair MuSK-Dok-7 interaction.

Journal: Human molecular genetics20100615

Title: T-cell receptor early signalling complex activation in response to interferon-alpha receptor stimulation.

Journal: The Biochemical journal20100615

Title: Probing protein kinase (CK2) and alkaline phosphatase with CdSe/ZnS quantum dots.

Journal: Nano letters20100609

Title: Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology.

Journal: Journal of proteome research20100604

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling in diabetes prone and resistant mice.

Journal: Journal of proteome research20100604

Title: Genomic Analysis Highlights the Role of the JAK-STAT Signaling in the Anti-proliferative Effects of Dietary Flavonoid-'Ashwagandha' in Prostate Cancer Cells.

Journal: Evidence-based complementary and alternative medicine : eCAM20100601

Title: I-BAR domains, IRSp53 and filopodium formation.

Journal: Seminars in cell & developmental biology20100601

Title: Glomerular proteins related to slit diaphragm and matrix adhesion in the foot processes are highly tyrosine phosphorylated in the normal rat kidney.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20100601

Title: Phosphorylation of thymidylate synthase from various sources by human protein kinase CK2 and its catalytic subunits.

Journal: Bioorganic chemistry20100601

Title: Trafficking defects and loss of ligand binding are the underlying causes of all reported DDR2 missense mutations found in SMED-SL patients.

Journal: Human molecular genetics20100601

Title: TBC1D1 regulates insulin- and contraction-induced glucose transport in mouse skeletal muscle.

Journal: Diabetes20100601

Title: Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue.

Journal: Diabetes20100601

Title: Proteins from human oviductal tissue-conditioned medium modulate sperm capacitation.

Journal: Human reproduction (Oxford, England)20100601

Title: A novel bile acid-activated vitamin D receptor signaling in human hepatocytes.

Journal: Molecular endocrinology (Baltimore, Md.)20100601

Title: Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2.

Journal: Journal of structural and functional genomics20100601

Title: Cytoskeleton-modulating effectors of enteropathogenic and enterohaemorrhagic Escherichia coli: Tir, EspFU and actin pedestal assembly.

Journal: The FEBS journal20100601

Title: RBC membrane damage and decreased band 3 phospho-tyrosine phosphatase activity are markers of COPD progression.

Journal: Frontiers in bioscience (Elite edition)20100601

Title: Molecular mechanism of insulin resistance in obesity and type 2 diabetes.

Journal: The Korean journal of internal medicine20100601

Title: Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis.

Journal: The FEBS journal20100601

Title: Whole-genome sequencing of a single proband together with linkage analysis identifies a Mendelian disease gene.

Journal: PLoS genetics20100601

Title: Plato's cave algorithm: inferring functional signaling networks from early gene expression shadows.

Journal: PLoS computational biology20100601

Title: A novel small-molecule disrupts Stat3 SH2 domain-phosphotyrosine interactions and Stat3-dependent tumor processes.

Journal: Biochemical pharmacology20100515

Title: The heterohexameric complex structure, a component in the non-classical pathway for fibroblast growth factor 1 (FGF1) secretion.

Journal: The Journal of biological chemistry20100514

Title: Insulin-like growth factor-binding protein 7 alters the sensitivity to interferon-based anticancer therapy in hepatocellular carcinoma cells.

Journal: British journal of cancer20100511

Title: c-Abl, Lamellipodin, and Ena/VASP proteins cooperate in dorsal ruffling of fibroblasts and axonal morphogenesis.

Journal: Current biology : CB20100511

Title: Heparan sulfate chain valency controls syndecan-4 function in cell adhesion.

Journal: The Journal of biological chemistry20100507

Title: Quantitative analysis of HGF and EGF-dependent phosphotyrosine signaling networks.

Journal: Journal of proteome research20100507

Title: Differential phosphoproteomics of fibroblast growth factor signaling: identification of Src family kinase-mediated phosphorylation events.

Journal: Journal of proteome research20100507

Title: An unnatural amino acid that mimics phosphotyrosine.

Journal: Chemical communications (Cambridge, England)20100507

Title: Analysis of novel phospho-ITAM specific antibodies in a S2 reconstitution system for TCR-CD3 signalling.

Journal: Immunology letters20100504

Title: Loops govern SH2 domain specificity by controlling access to binding pockets.

Journal: Science signaling20100504

Title: A robust error model for iTRAQ quantification reveals divergent signaling between oncogenic FLT3 mutants in acute myeloid leukemia.

Journal: Molecular & cellular proteomics : MCP20100501

Title: High glucose induces suppression of insulin signalling and apoptosis via upregulation of endogenous IL-1beta and suppressor of cytokine signalling-1 in mouse pancreatic beta cells.

Journal: Cellular signalling20100501

Title: The Bcr-Abl kinase regulates the actin cytoskeleton via a GADS/Slp-76/Nck1 adaptor protein pathway.

Journal: Cellular signalling20100501

Title: Protein tyrosine phosphatase SHP-1 positively regulates TLR-induced IL-12p40 production in macrophages through inhibition of phosphatidylinositol 3-kinase.

Journal: Journal of leukocyte biology20100501

Title: The pseudophosphatase MK-STYX interacts with G3BP and decreases stress granule formation.

Journal: The Biochemical journal20100501

Title: Regulation of hyperactivation by PPP2 in hamster spermatozoa.

Journal: Reproduction (Cambridge, England)20100501

Title: Tyrosine phosphorylation of SHIP promotes its proteasomal degradation.

Journal: Experimental hematology20100501

Title: Inhibition of c-Met with the specific small molecule tyrosine kinase inhibitor SU11274 decreases growth and metastasis formation of experimental human melanoma.

Journal: Current cancer drug targets20100501

Title: New Cdc2 Tyr 4 phosphorylation by dsRNA-activated protein kinase triggers Cdc2 polyubiquitination and G2 arrest under genotoxic stresses.

Journal: EMBO reports20100501

Title: Asymmetric tyrosine kinase arrangements in activation or autophosphorylation of receptor tyrosine kinases.

Journal: Molecules and cells20100501

Title: Leishmania donovani isolates with antimony-resistant but not -sensitive phenotype inhibit sodium antimony gluconate-induced dendritic cell activation.

Journal: PLoS pathogens20100501

Title: Protein kinase Cθ is required for cardiomyocyte survival and cardiac remodeling.

Journal: Cell death & disease20100501

Title: VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts.

Journal: The EMBO journal20100421

Title: Deoxygenation affects tyrosine phosphoproteome of red cell membrane from patients with sickle cell disease.

Journal: Blood cells, molecules & diseases20100415

Title: Regulation of vascular endothelial function by procyanidin-rich foods and beverages.

Journal: Journal of agricultural and food chemistry20100414

Title: Novel monoclonal antibodies recognizing the active conformation of epidermal growth factor receptor.

Journal: Biochemical and biophysical research communications20100409

Title: Insulin receptor substrate-3, interacting with Bcl-3, enhances p50 NF-kappaB activity.

Journal: Biochemical and biophysical research communications20100409

Title: The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion.

Journal: The Journal of biological chemistry20100402

Title: Effects of micrometric titanium particles on osteoblast attachment and cytoskeleton architecture.

Journal: Acta biomaterialia20100401

Title: Increased CYP2J3 expression reduces insulin resistance in fructose-treated rats and db/db mice.

Journal: Diabetes20100401

Title: FcepsilonRI beta-chain ITAM amplifies PI3K-signaling to ensure synergistic degranulation response via FcepsilonRI and adenosine receptors.

Journal: European journal of immunology20100401

Title: Differential phosphorylation of functional tyrosines in CD19 modulates B-lymphocyte activation.

Journal: European journal of immunology20100401

Title: Impact of rs361072 in the phosphoinositide 3-kinase p110beta gene on whole-body glucose metabolism and subunit protein expression in skeletal muscle.

Journal: Diabetes20100401

Title: Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance.

Journal: Journal of biochemistry20100401

Title: Screening kinase inhibitors with a microarray-based fluorescent and resonance light scattering assay.

Journal: Analytical chemistry20100401

Title: Anergic CD4+ T cells form mature immunological synapses with enhanced accumulation of c-Cbl and Cbl-b.

Journal: Journal of immunology (Baltimore, Md. : 1950)20100401

Title: A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain.

Journal: Nature structural & molecular biology20100401

Title: Metabolic network topology reveals transcriptional regulatory signatures of type 2 diabetes.

Journal: PLoS computational biology20100401

Title: Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3.

Journal: Molecular cancer therapeutics20100401

Title: [New functional proteins identified by proteomic analysis in the epidermal growth factor receptor-mediated signaling pathway and application for practical use].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan20100401

Title: Detecting tyrosine-phosphorylated proteins by Western blot analysis.

Journal: Current protocols in immunology20100401

Title: Role of the osmotic stress regulatory pathway in morphogenesis and secondary metabolism in filamentous fungi.

Journal: Toxins20100401

Title: A double point mutation in PCL-gamma1 (Y509A/F510A) enhances Y783 phosphorylation and inositol phospholipid-hydrolyzing activity upon EGF stimulation.

Journal: Experimental & molecular medicine20100331

Title: NOS1AP associates with Scribble and regulates dendritic spine development.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20100331

Title: Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survival.

Journal: The Journal of biological chemistry20100326

Title: Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm.

Journal: The Journal of biological chemistry20100326

Title: CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development.

Journal: Immunity20100326

Title: Quantitative reconstitution of mitotic CDK1 activation in somatic cell extracts.

Journal: Molecular cell20100326

Title: Functional interaction of the Ras effector RASSF5 with the tyrosine kinase Lck: critical role in nucleocytoplasmic transport and cell cycle regulation.

Journal: Journal of molecular biology20100319

Title: Regulation of actin polymerization and adhesion-dependent cell edge protrusion by the Abl-related gene (Arg) tyrosine kinase and N-WASp.

Journal: Biochemistry20100316

Title: A new Dictyostelium prestalk cell sub-type.

Journal: Developmental biology20100315

Title: Insufficient deactivation of the protein tyrosine kinase lck amplifies T-cell responsiveness in acute coronary syndrome.

Journal: Circulation research20100305

Title: p66shc inhibits insulin-like growth factor-I signaling via direct binding to Src through its polyproline and Src homology 2 domains, resulting in impairment of Src kinase activation.

Journal: The Journal of biological chemistry20100305

Title: The PTB domain of ShcA couples receptor activation to the cytoskeletal regulator IQGAP1.

Journal: The EMBO journal20100303

Title: AMP N(1)-oxide, a unique compound of royal jelly, induces neurite outgrowth from PC12 cells via signaling by protein kinase A independent of that by mitogen-activated protein kinase.

Journal: Evidence-based complementary and alternative medicine : eCAM20100301

Title: Fabrication and characterization of a recombinant fibronectin/cadherin bio-inspired ceramic surface and its influence on adhesion and ossification in vitro.

Journal: Acta biomaterialia20100301

Title: Orexins/hypocretins and orexin receptors in apoptosis: a mini-review.

Journal: Acta physiologica (Oxford, England)20100301

Title: Regulation of tyrosine kinase activity during capacitation in goat sperm.

Journal: Molecular and cellular biochemistry20100301

Title: Human IL6 enhances leptin action in mice.

Journal: Diabetologia20100301

Title: Effects of angiopoietins-1 and -2 on the receptor tyrosine kinase Tie2 are differentially regulated at the endothelial cell surface.

Journal: Cellular signalling20100301

Title: IGF-1 receptors in Xenopus laevis ovarian follicle cells support the oocyte maturation response.

Journal: Biology of reproduction20100301

Title: Cell membrane extensions, generated by mechanical constraint, are associated with a sustained lipid raft patching and an increased cell signaling.

Journal: Biochimica et biophysica acta20100301

Title: Role of protein tyrosine phosphatase SHP2 in barrier function of pulmonary endothelium.

Journal: American journal of physiology. Lung cellular and molecular physiology20100301

Title: Prolactin exerts a prosurvival effect on human spermatozoa via mechanisms that involve the stimulation of Akt phosphorylation and suppression of caspase activation and capacitation.

Journal: Endocrinology20100301

Title: Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation.

Journal: Journal of thrombosis and haemostasis : JTH20100301

Title: Global phosphoproteomic effects of natural tyrosine kinase inhibitor, genistein, on signaling pathways.

Journal: Proteomics20100301

Title: Prepubertal genistein exposure affects erbB2/Akt signal and reduces rat mammary tumorigenesis.

Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)20100301

Title: TIMP-2 modulates VEGFR-2 phosphorylation and enhances phosphodiesterase activity in endothelial cells.

Journal: Laboratory investigation; a journal of technical methods and pathology20100301

Title: APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis.

Journal: Brain structure & function20100301

Title: Effect of paraquat-induced oxidative stress on insulin regulation of insulin-like growth factor-binding protein-1 gene expression.

Journal: Journal of clinical biochemistry and nutrition20100301

Title: Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response.

Journal: PLoS biology20100301

Title: Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk.

Journal: PLoS genetics20100301

Title: Helicobacter pylori lipopolysaccharide is synthesized via a novel pathway with an evolutionary connection to protein N-glycosylation.

Journal: PLoS pathogens20100301

Title: Appl1 is dispensable for mouse development, and loss of Appl1 has growth factor-selective effects on Akt signaling in murine embryonic fibroblasts.

Journal: The Journal of biological chemistry20100226

Title: Alpha2,6-sialic acid on platelet endothelial cell adhesion molecule (PECAM) regulates its homophilic interactions and downstream antiapoptotic signaling.

Journal: The Journal of biological chemistry20100226

Title: A novel Thr56Met mutation of the autosomal recessive hypercholesterolemia gene associated with hypercholesterolemia.

Journal: Journal of atherosclerosis and thrombosis20100226

Title: Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation.

Journal: Molecular cell20100226

Title: Roles of the intramolecular regions of FE65 in its trans-accumulation and in p53 stabilization in the nuclear matrix of osmotically stressed cells.

Journal: FEBS letters20100219

Title: Bacterial pleckstrin homology domains: a prokaryotic origin for the PH domain.

Journal: Journal of molecular biology20100212

Title: Major role of epidermal growth factor receptor and Src kinases in promoting oxidative stress-dependent loss of adhesion and apoptosis in epithelial cells.

Journal: The Journal of biological chemistry20100212

Title: Phosphotyrosine confers client specificity to Hsp90.

Journal: Molecular cell20100212

Title: Activity and cellular localization of an oncogenic glioblastoma multiforme-associated EGF receptor mutant possessing a duplicated kinase domain.

Journal: Oncogene20100211

Title: Proteomic analysis of Src family kinases signaling complexes in Golgi/endosomal fractions using a site-selective anti-phosphotyrosine antibody: identification of LRP1-insulin receptor complexes.

Journal: Journal of proteome research20100205

Title: Induction of myeloproliferative disorder and myelofibrosis by thrombopoietin receptor W515 mutants is mediated by cytosolic tyrosine 112 of the receptor.

Journal: Blood20100204

Title: Na+/K+ATPase regulates sperm capacitation through a mechanism involving kinases and redistribution of its testis-specific isoform.

Journal: Molecular reproduction and development20100201

Title: Performance metrics for liquid chromatography-tandem mass spectrometry systems in proteomics analyses.

Journal: Molecular & cellular proteomics : MCP20100201

Title: Protein tyrosine phosphatases in glioma biology.

Journal: Acta neuropathologica20100201

Title: Quantifying oncogenic phosphotyrosine signaling networks through systems biology.

Journal: Current opinion in genetics & development20100201

Title: The Wnt pathway controls cell death engulfment, spindle orientation, and migration through CED-10/Rac.

Journal: PLoS biology20100201

Title: The Syk kinase SmTK4 of Schistosoma mansoni is involved in the regulation of spermatogenesis and oogenesis.

Journal: PLoS pathogens20100201

Title: A novel pseudopodial component of the dendritic cell anti-fungal response: the fungipod.

Journal: PLoS pathogens20100201

Title: Dual specificity phosphatase16 is a negative regulator of c-Jun NH2-terminal kinase activity in T cells.

Journal: Microbiology and immunology20100201

Title: Peptide-based activity-based probes (ABPs) for target-specific profiling of protein tyrosine phosphatases (PTPs).

Journal: Chemical communications (Cambridge, England)20100128

Title: Amlodipine, a Ca2+ channel blocker, suppresses phosphorylation of epidermal growth factor receptor in human epidermoid carcinoma A431 cells.

Journal: Life sciences20100116

Title: Identification of beta-catenin as a target of the intracellular tyrosine kinase PTK6.

Journal: Journal of cell science20100115

Title: The somatostatin analogue octreotide confers sensitivity to rapamycin treatment on pituitary tumor cells.

Journal: Cancer research20100115

Title: Prognostic effect of activated EGFR expression in human colon carcinomas: comparison with EGFR status.

Journal: British journal of cancer20100105

Title: The involvement of suppressors of cytokine signaling 2 (SOCS2) in immune defense responses of Chinese mitten crab Eriocheir sinensis.

Journal: Developmental and comparative immunology20100101

Title: Individual domains of Tensin2 exhibit distinct subcellular localisations and migratory effects.

Journal: The international journal of biochemistry & cell biology20100101

Title: The effect of anti-eppin antibodies on ionophore A23187-induced calcium influx and acrosome reaction of human spermatozoa.

Journal: Human reproduction (Oxford, England)20100101

Title: Apoptosis induction in BEFV-infected Vero and MDBK cells through Src-dependent JNK activation regulates caspase-3 and mitochondria pathways.

Journal: Veterinary research20100101

Title: Cancer systems biology: a network modeling perspective.

Journal: Carcinogenesis20100101

Title: Reactive oxygen species are signalling molecules for skeletal muscle adaptation.

Journal: Experimental physiology20100101

Title: Functional characterization of the kinase activation loop in nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) using tandem affinity purification and liquid chromatography-mass spectrometry.

Journal: The Journal of biological chemistry20100101

Title: Alpha5beta1 integrin engagement increases large conductance, Ca2+-activated K+ channel current and Ca2+ sensitivity through c-src-mediated channel phosphorylation.

Journal: The Journal of biological chemistry20100101

Title: Antioxidant-induced phosphorylation of tyrosine 486 leads to rapid nuclear export of Bach1 that allows Nrf2 to bind to the antioxidant response element and activate defensive gene expression.

Journal: The Journal of biological chemistry20100101

Title: Functional and structural characterization of the talin F0F1 domain.

Journal: Biochemical and biophysical research communications20100101

Title: Targeting the epidermal growth factor receptor in epithelial ovarian cancer: current knowledge and future challenges.

Journal: Journal of oncology20100101

Title: Toxicological disruption of signaling homeostasis: tyrosine phosphatases as targets.

Journal: Annual review of pharmacology and toxicology20100101

Title: Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase.

Journal: BMC cancer20100101

Title: Mechanism of attenuation of leptin signaling under chronic ligand stimulation.

Journal: BMC biochemistry20100101

Title: Transcriptomic profiling of bovine IVF embryos revealed candidate genes and pathways involved in early embryonic development.

Journal: BMC genomics20100101

Title: Novel role of phosphorylation-dependent interaction between FtsZ and FipA in mycobacterial cell division.

Journal: PloS one20100101

Title: Cell aggregation induces phosphorylation of PECAM-1 and Pyk2 and promotes tumor cell anchorage-independent growth.

Journal: Molecular cancer20100101

Title: Differential requirement of the epidermal growth factor receptor for G protein-mediated activation of transcription factors by lysophosphatidic acid.

Journal: Molecular cancer20100101

Title: Identification of calcium-binding proteins associated with the human sperm plasma membrane.

Journal: Reproductive biology and endocrinology : RB&E20100101

Title: Identification of possible targets of the Aspergillus fumigatus CRZ1 homologue, CrzA.

Journal: BMC microbiology20100101

Title: Marburg virus evades interferon responses by a mechanism distinct from ebola virus.

Journal: PLoS pathogens20100101

Title: Cooperativity within proximal phosphorylation sites is revealed from large-scale proteomics data.

Journal: Biology direct20100101

Title: Protein tyrosine phosphatase 1B gene polymorphisms and essential hypertension: a case-control study in Chinese population.

Journal: Journal of endocrinological investigation20100101

Title: Lineage-specific co-evolution of the Egf receptor/ligand signaling system.

Journal: BMC evolutionary biology20100101

Title: CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases.

Journal: PloS one20100101

Title: Vertebrate Lrig3-ErbB interactions occur in vitro but are unlikely to play a role in Lrig3-dependent inner ear morphogenesis.

Journal: PloS one20100101

Title: Biochemical profiling of histone binding selectivity of the yeast bromodomain family.

Journal: PloS one20100101

Title: Site-directed mutagenesis reveals a unique requirement for tyrosine residues in IL-7Ralpha and TSLPR cytoplasmic domains in TSLP-dependent cell proliferation.

Journal: BMC immunology20100101

Title: Posttranslational modifications, localization, and protein interactions of optineurin, the product of a glaucoma gene.

Journal: PloS one20100101

Title: Dystroglycan versatility in cell adhesion: a tale of multiple motifs.

Journal: Cell communication and signaling : CCS20100101

Title: Exposure of beta-tubulin regions defined by antibodies on an Arabidopsis thaliana microtubule protofilament model and in the cells.

Journal: BMC plant biology20100101

Title: IL-9 induces CCL11 expression via STAT3 signalling in human airway smooth muscle cells.

Journal: PloS one20100101

Title: Angiotensin II type 2 receptor signaling significantly attenuates growth of murine pancreatic carcinoma grafts in syngeneic mice.

Journal: BMC cancer20100101

Title: Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease.

Journal: Molecular neurodegeneration20100101

Title: The structural insights of stem cell factor receptor (c-Kit) interaction with tyrosine phosphatase-2 (Shp-2): an in silico analysis.

Journal: BMC research notes20100101

Title: Mass spectrometric analysis of Ehrlichia chaffeensis tandem repeat proteins reveals evidence of phosphorylation and absence of glycosylation.

Journal: PloS one20100101

Title: Masitinib combined with standard gemcitabine chemotherapy: in vitro and in vivo studies in human pancreatic tumour cell lines and ectopic mouse model.

Journal: PloS one20100101

Title: Developmental and oncogenic effects of insulin-like growth factor-I in Ptc1+/- mouse cerebellum.

Journal: Molecular cancer20100101

Title: High-throughput kinase assay based on surface plasmon resonance.

Journal: Methods in molecular biology (Clifton, N.J.)20100101

Title: Phosphotyrosine phosphatases in cancer diagnostic and treatment.

Journal: Recent patents on DNA & gene sequences20100101

Title: Comparative genomics and proteomics of Helicobacter mustelae, an ulcerogenic and carcinogenic gastric pathogen.

Journal: BMC genomics20100101

Title: Role of prostaglandin E receptor subtypes EP2 and EP4 in autocrine and paracrine functions of vascular endothelial growth factor in the inner ear.

Journal: BMC neuroscience20100101

Title: The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathways.

Journal: PloS one20100101

Title: Insulin receptor signaling in the development of neuronal structure and function.

Journal: Neural development20100101

Title: Stoichiometry and intracellular fate of TRIM-containing TCR complexes.

Journal: Cell communication and signaling : CCS20100101

Title: Adhesion of monocytes to type I collagen stimulates an APP-dependent proinflammatory signaling response and release of Abeta1-40.

Journal: Journal of neuroinflammation20100101

Title: T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.

Journal: PloS one20100101

Title: Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation.

Journal: PloS one20100101

Title: Tiam1 as a signaling mediator of nerve growth factor-dependent neurite outgrowth.

Journal: PloS one20100101

Title: Hepatitis B virus X protein impairs hepatic insulin signaling through degradation of IRS1 and induction of SOCS3.

Journal: PloS one20100101

Title: In the absence of frazzled over-expression of Abelson tyrosine kinase disrupts commissure formation and causes axons to leave the embryonic CNS.

Journal: PloS one20100101

Title: Structural and functional studies of STAT1 from Atlantic salmon (Salmo salar).

Journal: BMC immunology20100101

Title: Quantifying protein-protein interactions in high throughput using protein domain microarrays.

Journal: Nature protocols20100101

Title: Arabidopsis thaliana GYRB3 does not encode a DNA gyrase subunit.

Journal: PloS one20100101

Title: Characterization of trophoblast and extraembryonic endoderm cell lineages derived from rat preimplantation embryos.

Journal: PloS one20100101

Title: Applying mass spectrometry based proteomic technology to advance the understanding of multiple myeloma.

Journal: Journal of hematology & oncology20100101

Title: Effects of (-)-epigallocatechin gallate on RPE cell migration and adhesion.

Journal: Molecular vision20100101

Title: Vasectomy affects cysteine-rich secretory protein expression along the human epididymis and its association with ejaculated spermatozoa following vasectomy surgical reversal.

Journal: Journal of andrology20100101

Title: Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy.

Journal: Molecular cancer20100101

Title: Leishmania interferes with host cell signaling to devise a survival strategy.

Journal: Journal of biomedicine & biotechnology20100101

Title: Key signalling nodes in mammary gland development and cancer. Signalling downstream of PI3 kinase in mammary epithelium: a play in 3 Akts.

Journal: Breast cancer research : BCR20100101

Title: Binding-site assessment by virtual fragment screening.

Journal: PloS one20100101

Title: PI3Kp110-, Src-, FAK-dependent and DOCK2-independent migration and invasion of CXCL13-stimulated prostate cancer cells.

Journal: Molecular cancer20100101

Title: Hypoxia induces differential translation of enolase/MBP-1.

Journal: BMC cancer20100101

Title: Critical role of FLRT1 phosphorylation in the interdependent regulation of FLRT1 function and FGF receptor signalling.

Journal: PloS one20100101

Title: Extracellular SOD-derived H2O2 promotes VEGF signaling in caveolae/lipid rafts and post-ischemic angiogenesis in mice.

Journal: PloS one20100101

Title: A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist.

Journal: PloS one20100101

Title: PhosphoGRID: a database of experimentally verified in vivo protein phosphorylation sites from the budding yeast Saccharomyces cerevisiae.

Journal: Database : the journal of biological databases and curation20100101

Title: In vivo tumor cell adhesion in the pulmonary microvasculature is exclusively mediated by tumor cell--endothelial cell interaction.

Journal: BMC cancer20100101

Title: Spatio-temporal modeling of signaling protein recruitment to EGFR.

Journal: BMC systems biology20100101

Title: A novel synthetic analog of 5, 8-disubstituted quinazolines blocks mitosis and induces apoptosis of tumor cells by inhibiting microtubule polymerization.

Journal: PloS one20100101

Title: Stat3: linking inflammation to epithelial cancer - more than a 'gut' feeling?

Journal: Cell division20100101

Title: Fluoride effects: the two faces of janus.

Journal: Current medicinal chemistry20100101

Title: The dawn of a new era in cell signalling research.

Journal: Cell communication and signaling : CCS20100101

Title: Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition.

Journal: Molecular cancer20100101

Title: Prolonged activation of S6K1 does not suppress IRS or PI-3 kinase signaling during muscle cell differentiation.

Journal: BMC cell biology20100101

Title: Arecoline induces HA22T/VGH hepatoma cells to undergo anoikis - involvement of STAT3 and RhoA activation.

Journal: Molecular cancer20100101

Title: PDZ domains and their binding partners: structure, specificity, and modification.

Journal: Cell communication and signaling : CCS20100101

Title: Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics.

Journal: Molecular cancer20100101

Title: Understanding the role of PknJ in Mycobacterium tuberculosis: biochemical characterization and identification of novel substrate pyruvate kinase A.

Journal: PloS one20100101

Title: Vicrostatin - an anti-invasive multi-integrin targeting chimeric disintegrin with tumor anti-angiogenic and pro-apoptotic activities.

Journal: PloS one20100101

Title: Structural and dynamical effects induced by the anticancer drug topotecan on the human topoisomerase I - DNA complex.

Journal: PloS one20100101

Title: Factors that may impact on immunosenescence: an appraisal.

Journal: Immunity & ageing : I & A20100101

Title: Phosphorylation State-Dependent High Throughput Screening of the c-Met Kinase.

Journal: Current chemical genomics20100101

Title: Etk/Bmx regulates proteinase-activated-receptor1 (PAR1) in breast cancer invasion: signaling partners, hierarchy and physiological significance.

Journal: PloS one20100101

Title: YopH inhibits early pro-inflammatory cytokine responses during plague pneumonia.

Journal: BMC immunology20100101

Title: The phosphatomes of the multicellular myxobacteria Myxococcus xanthus and Sorangium cellulosum in comparison with other prokaryotic genomes.

Journal: PloS one20100101

Title: Conformational determinants of phosphotyrosine peptides complexed with the Src SH2 domain.

Journal: PloS one20100101

Title: Low doses of ionizing radiation promote tumor growth and metastasis by enhancing angiogenesis.

Journal: PloS one20100101

Title: The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor.

Journal: Cell communication and signaling : CCS20100101

Title: A novel mechanism of cell growth regulation by Cell Cycle and Apoptosis Regulatory Protein (CARP)-1.

Journal: Journal of molecular signaling20100101

Title: A new approach to comparing anti-CD20 antibodies: importance of the lipid rafts in their lytic efficiency.

Journal: OncoTargets and therapy20100101

Title: Nm23-H1 suppresses hepatocarcinoma cell adhesion and migration on fibronectin by modulating glycosylation of integrin beta1.

Journal: Journal of experimental & clinical cancer research : CR20100101

Title: Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression.

Journal: Molecular cancer20100101

Title: Gonadotropin-releasing hormone type II antagonist induces apoptosis in MCF-7 and triple-negative MDA-MB-231 human breast cancer cells in vitro and in vivo.

Journal: Breast cancer research : BCR20100101

Title: Motesanib inhibits Kit mutations associated with gastrointestinal stromal tumors.

Journal: Journal of experimental & clinical cancer research : CR20100101

Title: Protein phosphatase complement in rice: genome-wide identification and transcriptional analysis under abiotic stress conditions and reproductive development.

Journal: BMC genomics20100101

Title: Neural membrane signaling platforms.

Journal: International journal of molecular sciences20100101

Title: Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production.

Journal: PloS one20100101

Title: Thy-1 attenuates TNF-alpha-activated gene expression in mouse embryonic fibroblasts via Src family kinase.

Journal: PloS one20100101

Title: Transactivation of PDGFRbeta by dopamine D4 receptor does not require PDGFRbeta dimerization.

Journal: Molecular brain20100101

Title: A limited role for PI(3,4,5)P3 regulation in controlling skeletal muscle mass in response to resistance exercise.

Journal: PloS one20100101

Title: Adhesion and degranulation promoting adapter protein (ADAP) is a central hub for phosphotyrosine-mediated interactions in T cells.

Journal: PloS one20100101

Title: Gene expression analysis after receptor tyrosine kinase activation reveals new potential melanoma proteins.

Journal: BMC cancer20100101

Title: Gene expression profile of epithelial cells and mesenchymal cells derived from limbal explant culture.

Journal: Molecular vision20100101

Title: A genetic screen for anchorage-independent proliferation in mammalian cells identifies a membrane-bound neuregulin.

Journal: PloS one20100101

Title: Personalized therapies in the cancer 'omics' era.

Journal: Molecular cancer20100101

Title: A new family of phosphoinositide phosphatases in microorganisms: identification and biochemical analysis.

Journal: BMC genomics20100101

Title: Peptidomimetic competitive inhibitors of protein tyrosine phosphatases.

Journal: Current pharmaceutical design20100101

Title: EPO receptor gain-of-function causes hereditary polycythemia, alters CD34 cell differentiation and increases circulating endothelial precursors.

Journal: PloS one20100101

Title: Fluidization and resolidification of the human bladder smooth muscle cell in response to transient stretch.

Journal: PloS one20100101

Title: Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death.

Journal: Experimental & translational stroke medicine20100101

Title: Interleukin-27 acts on hepatic stellate cells and induces signal transducer and activator of transcription 1-dependent responses.

Journal: Cell communication and signaling : CCS20100101

Title: Microglial immunoreceptor tyrosine-based activation and inhibition motif signaling in neuroinflammation.

Journal: International journal of Alzheimer's disease20100101

Title: The activation of Proteinase-Activated Receptor-1 (PAR1) mediates gastric cancer cell proliferation and invasion.

Journal: BMC cancer20100101

Title: Suppression of uPA and uPAR attenuates angiogenin mediated angiogenesis in endothelial and glioblastoma cell lines.

Journal: PloS one20100101

Title: Dasatinib synergizes with JSI-124 to inhibit growth and migration and induce apoptosis of malignant human glioma cells.

Journal: Journal of carcinogenesis20100101

Title: Partitioning of minimotifs based on function with improved prediction accuracy.

Journal: PloS one20100101

Title: Molecular mechanistic associations of human diseases.

Journal: BMC systems biology20100101

Title: Ephrin-A5 and EphA5 interaction induces synaptogenesis during early hippocampal development.

Journal: PloS one20100101

Title: Menin and RNF20 recruitment is associated with dynamic histone modifications that regulate signal transducer and activator of transcription 1 (STAT1)-activated transcription of the interferon regulatory factor 1 gene (IRF1).

Journal: Epigenetics & chromatin20100101

Title: Experimental assessment of pro-lymphangiogenic growth factors in the treatment of post-surgical lymphedema following lymphadenectomy.

Journal: Breast cancer research : BCR20100101

Title: The role of the JAK2-STAT3 pathway in pro-inflammatory responses of EMF-stimulated N9 microglial cells.

Journal: Journal of neuroinflammation20100101

Title: Calcium regulation of EGF-induced ERK5 activation: role of Lad1-MEKK2 interaction.

Journal: PloS one20100101

Title: Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain.

Journal: Molecular neurodegeneration20100101

Title: CXCL10 can inhibit endothelial cell proliferation independently of CXCR3.

Journal: PloS one20100101

Title: Isolation of detergent resistant microdomains from cultured neurons: detergent dependent alterations in protein composition.

Journal: BMC neuroscience20100101

Title: PeptideMine--a webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactomes.

Journal: BMC bioinformatics20100101

Title: Additional serine/threonine phosphorylation reduces binding affinity but preserves interface topography of substrate proteins to the c-Cbl TKB domain.

Journal: PloS one20100101

Title: Integrated ligand-receptor bioinformatic and in vitro functional analysis identifies active TGFA/EGFR signaling loop in papillary thyroid carcinomas.

Journal: PloS one20100101

Title: Quantitative phosphoproteomic analysis of prion-infected neuronal cells.

Journal: Cell communication and signaling : CCS20100101

Title: The DNA relaxation activity and covalent complex accumulation of Mycobacterium tuberculosis topoisomerase I can be assayed in Escherichia coli: application for identification of potential FRET-dye labeling sites.

Journal: BMC biochemistry20100101

Title: Mechanical stress activates Smad pathway through PKCδ to enhance interleukin-11 gene transcription in osteoblasts.

Journal: PloS one20100101

Title: Quantitative phosphoproteomics of proteasome inhibition in multiple myeloma cells.

Journal: PloS one20100101

Title: The role of the focal adhesion protein PINCH1 for the radiosensitivity of adhesion and suspension cell cultures.

Journal: PloS one20100101

Title: Epigenetic regulation of CpG promoter methylation in invasive prostate cancer cells.

Journal: Molecular cancer20100101

Title: Interaction of human dipeptidyl peptidase IV and human immunodeficiency virus type-1 transcription transactivator in Sf9 cells.

Journal: Virology journal20100101

Title: Differential genetic regulation of canine hip dysplasia and osteoarthritis.

Journal: PloS one20100101

Title: SH2 modified STAT1 induces HLA-I expression and improves IFN-γ signaling in IFN-α resistant HCV replicon cells.

Journal: PloS one20100101

Title: Dasatinib reduces FAK phosphorylation increasing the effects of RPI-1 inhibition in a RET/PTC1-expressing cell line.

Journal: Molecular cancer20100101

Title: Identification of tetranectin as a potential biomarker for metastatic oral cancer.

Journal: International journal of molecular sciences20100101

Title: Chimeric design, synthesis, and biological assays of a new nonpeptide insulin-mimetic vanadium compound to inhibit protein tyrosine phosphatase 1B.

Journal: Drug design, development and therapy20100101

Title: Tyrosine phosphorylation of Grb14 by Tie2.

Journal: Cell communication and signaling : CCS20100101

Title: Characterizing tyrosine phosphorylation signaling in lung cancer using SH2 profiling.

Journal: PloS one20100101

Title: Hypercholesterolemia impaired sperm functionality in rabbits.

Journal: PloS one20100101

Title: Proteins involved in platelet signaling are differentially regulated in acute coronary syndrome: a proteomic study.

Journal: PloS one20100101

Title: Growth factor regulation of proliferation and survival of multipotential stromal cells.

Journal: Stem cell research & therapy20100101

Title: A Toll-like receptor-responsive kinase, protein kinase R, is inactivated in endotoxin tolerance through differential K63/K48 ubiquitination.

Journal: mBio20100101

Title: Regulation of Ack1 localization and activity by the amino-terminal SAM domain.

Journal: BMC biochemistry20100101

Title: Z-360, a novel therapeutic agent for pancreatic cancer, prevents up-regulation of ephrin B1 gene expression and phosphorylation of NR2B via suppression of interleukin-1 β production in a cancer-induced pain model in mice.

Journal: Molecular pain20100101

Title: Genistein attenuates retinal inflammation associated with diabetes by targeting of microglial activation.

Journal: Molecular vision20100101

Title: Profiling Y561-dependent and -independent substrates of CSF-1R in epithelial cells.

Journal: PloS one20100101

Title: Characterization of in vivo keratin 19 phosphorylation on tyrosine-391.

Journal: PloS one20100101

Title: Palmitate and insulin synergistically induce IL-6 expression in human monocytes.

Journal: Cardiovascular diabetology20100101

Title: Characterization of human platelet binding of recombinant T cell receptor ligand.

Journal: Journal of neuroinflammation20100101

Title: Role of the VEGF-Flt-1-FAK pathway in the pathogenesis of osteoclastic bone destruction of giant cell tumors of bone.

Journal: Journal of orthopaedic surgery and research20100101

Title: FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy.

Journal: PloS one20100101

Title: Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects.

Journal: PloS one20100101

Title: Mitochondrial tyrosine phosphoproteome: new insights from an up-to-date analysis.

Journal: BioFactors (Oxford, England)20100101

Title: Versican G3 promotes mouse mammary tumor cell growth, migration, and metastasis by influencing EGF receptor signaling.

Journal: PloS one20100101

Title: Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells.

Journal: Breast cancer research : BCR20100101

Title: Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling.

Journal: PloS one20100101

Title: Clinical application for the preservation of phospho-proteins through in-situ tissue stabilization.

Journal: Proteome science20100101

Title: RhoH regulates subcellular localization of ZAP-70 and Lck in T cell receptor signaling.

Journal: PloS one20100101

Title: Reactive oxygen species are required for maintenance and differentiation of primary lung fibroblasts in idiopathic pulmonary fibrosis.

Journal: PloS one20100101

Title: Deletion or insertion in the first immunoglobulin-plexin-transcription (IPT) domain differentially regulates expression and tumorigenic activities of RON receptor Tyrosine Kinase.

Journal: Molecular cancer20100101

Title: Two novel human NUMB isoforms provide a potential link between development and cancer.

Journal: Neural development20100101

Title: The Fer tyrosine kinase regulates interactions of Rho GDP-Dissociation Inhibitor α with the small GTPase Rac.

Journal: BMC biochemistry20100101

Title: The kinome of Phytophthora infestans reveals oomycete-specific innovations and links to other taxonomic groups.

Journal: BMC genomics20100101

Title: XAF1 expression and regulatory effects of somatostatin on XAF1 in prostate cancer cells.

Journal: Journal of experimental & clinical cancer research : CR20100101

Title: Cdk1 and SUMO regulate Swe1 stability.

Journal: PloS one20100101

Title: Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src.

Journal: PloS one20100101

Title: T cell receptor signal initiation induced by low-grade stimulation requires the cooperation of LAT in human T cells.

Journal: PloS one20100101

Title: Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression.

Journal: PloS one20100101

Title: Trace elements in glucometabolic disorders: an update.

Journal: Diabetology & metabolic syndrome20100101

Title: CSPG is a secreted factor that stimulates neural stem cell survival possibly by enhanced EGFR signaling.

Journal: PloS one20100101

Title: Matched sizes of activating and inhibitory receptor/ligand pairs are required for optimal signal integration by human natural killer cells.

Journal: PloS one20100101

Title: Phosphorylation meets nuclear import: a review.

Journal: Cell communication and signaling : CCS20100101

Title: A serum factor induces insulin-independent translocation of GLUT4 to the cell surface which is maintained in insulin resistance.

Journal: PloS one20100101

Title: Role of lapatinib in the first-line treatment of patients with metastatic breast cancer.

Journal: Cancer management and research20100101

Title: Role of erlotinib in first-line and maintenance treatment of advanced non-small-cell lung cancer.

Journal: Cancer management and research20100101

Title: Ligand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cells.

Journal: PloS one20100101

Title: Endotoxin mediated-iNOS induction causes insulin resistance via ONOO⁻ induced tyrosine nitration of IRS-1 in skeletal muscle.

Journal: PloS one20100101

Title: Glycolipid-Dependent, Protease Sensitive Internalization of Pseudomonas aeruginosa Into Cultured Human Respiratory Epithelial Cells.

Journal: The open microbiology journal20100101

Title: c-Abl phosphorylation of ΔNp63α is critical for cell viability.

Journal: Cell death & disease20100101

Title: c-Abl downregulates the slow phase of double-strand break repair.

Journal: Cell death & disease20100101

Title: Protein microarrays and biomarkers of infectious disease.

Journal: International journal of molecular sciences20100101

Title: Exploitation of host cell biology and evasion of immunity by francisella tularensis.

Journal: Frontiers in microbiology20100101

Title: Adherence to and invasion of host cells by spotted Fever group rickettsia species.

Journal: Frontiers in microbiology20100101

Title: The role of somatostatin in 67 consecutive pancreatectomies: a randomized clinical trial.

Journal: Clinical and experimental gastroenterology20100101

Title: Studies of Antimicrobial Activities of some 4-Thiazolidinone Fused Pyrimidines, [1,5]-Benzodiazepines and their Oxygen Substituted Hydroxylamine Derivatives.

Journal: Indian journal of pharmaceutical sciences20100101

Title: QSAR studies of benzofuran/benzothiophene biphenyl derivatives as inhibitors of PTPase-1B.

Journal: Journal of pharmacy & bioallied sciences20100101

Title: Proteasomal Degradation of Indoleamine 2,3-Dioxygenase in CD8 Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3).

Journal: International journal of tryptophan research : IJTR20100101

Title: Design strategies of fluorescent biosensors based on biological macromolecular receptors.

Journal: Sensors (Basel, Switzerland)20100101

Title: Secondary metabolites as DNA topoisomerase inhibitors: A new era towards designing of anticancer drugs.

Journal: Pharmacognosy reviews20100101

Title: Stress sensors and signal transducers in cyanobacteria.

Journal: Sensors (Basel, Switzerland)20100101

Title: Environmentally sensitive fluorescent sensors based on synthetic peptides.

Journal: Sensors (Basel, Switzerland)20100101

Title: Molecular basis of Mammalian embryonic stem cell pluripotency and self-renewal.

Journal: Acta naturae20100101

Title: Proteases that can distinguish among different post-translational forms of tyrosine engineered using multicolor flow cytometry.

Journal: Journal of the American Chemical Society20091223

Title: Epidermal growth factor receptor expression escapes androgen regulation in prostate cancer: a potential molecular switch for tumour growth.

Journal: British journal of cancer20091215

Title: Cell-specific information processing in segregating populations of Eph receptor ephrin-expressing cells.

Journal: Science (New York, N.Y.)20091211

Title: Crystallographic insight into collagen recognition by discoidin domain receptor 2.

Journal: Structure (London, England : 1993)20091209

Title: Modulation of human gingival fibroblast adhesion, morphology, tyrosine phosphorylation, and ERK 1/2 localization on polished, grooved and SLA substratum topographies.

Journal: Journal of biomedical materials research. Part A20091201

Title: Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics.

Journal: Molecular & cellular proteomics : MCP20091201

Title: Phosphoproteomics of Klebsiella pneumoniae NTUH-K2044 reveals a tight link between tyrosine phosphorylation and virulence.

Journal: Molecular & cellular proteomics : MCP20091201

Title: EGFR tyrosine kinase inhibitor (PD153035) improves glucose tolerance and insulin action in high-fat diet-fed mice.

Journal: Diabetes20091201

Title: Sphingosine-1-phosphate effects on the inner wall of Schlemm's canal and outflow facility in perfused human eyes.

Journal: Experimental eye research20091201

Title: Phosphotyrosine protein dynamics in cell membrane rafts of sphingosine-1-phosphate-stimulated human endothelium: role in barrier enhancement.

Journal: Cellular signalling20091201

Title: Urotensin II induces rat cardiomyocyte hypertrophy via the transient oxidization of Src homology 2-containing tyrosine phosphatase and transactivation of epidermal growth factor receptor.

Journal: Molecular pharmacology20091201

Title: Protein tyrosine kinase involvement in learning-produced changes in Hermissenda type B photoreceptors.

Journal: Journal of neurophysiology20091201

Title: Time-resolved observation of product ions generated by 157 nm photodissociation of singly protonated phosphopeptides.

Journal: Journal of the American Society for Mass Spectrometry20091201

Title: Molecular imaging of gefitinib activity in an epidermal growth factor receptor (EGFR)-bearing xenograft model.

Journal: Cancer biology & therapy20091201

Title: Endosomal proteolysis of internalised [ArgA0]-human insulin at neutral pH generates the mature insulin peptide in rat liver in vivo.

Journal: Diabetologia20091201

Title: Involvement of the c-jun N-terminal kinases JNK1 and JNK2 in complement-mediated cell death.

Journal: Molecular immunology20091201

Title: Comparison of protein expression in two prostate cancer cell-lines, LNCaP and DU145, after treatment with somatostatin.

Journal: Oncology reports20091201

Title: Ultraviolet photodissociation at 266 nm of phosphorylated peptide cations.

Journal: Rapid communications in mass spectrometry : RCM20091201

Title: Beryllium alters lipopolysaccharide-mediated intracellular phosphorylation and cytokine release in human peripheral blood mononuclear cells.

Journal: Journal of occupational and environmental hygiene20091201

Title: Inhibiton of RET and JAK2 signals and upregulation of VEGFR3 phosphorylation in vitro by galectin-1 in trophoblast tumor cells BeWo.

Journal: Placenta20091201

Title: SH2 domains: modulators of nonreceptor tyrosine kinase activity.

Journal: Current opinion in structural biology20091201

Title: Helicobacter pylori type IV secretion apparatus exploits beta1 integrin in a novel RGD-independent manner.

Journal: PLoS pathogens20091201

Title: Biology of urothelial tumorigenesis: insights from genetically engineered mice.

Journal: Cancer metastasis reviews20091201

Title: Swiprosin-1 Regulates Cytokine Expression of Human Mast Cell Line HMC-1 through Actin Remodeling.

Journal: Immune network20091201

Title: Incorporating support vector machine for identifying protein tyrosine sulfation sites.

Journal: Journal of computational chemistry20091130

Title: Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity.

Journal: Blood20091126

Title: PECAM-1 expression and activity negatively regulate multiple platelet signaling pathways.

Journal: FEBS letters20091119

Title: Amyloid precursor protein mediates a tyrosine kinase-dependent activation response in endothelial cells.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20091118

Title: Activity of the multikinase inhibitor dasatinib against ovarian cancer cells.

Journal: British journal of cancer20091117

Title: A reciprocal interdependence between Nck and PI(4,5)P(2) promotes localized N-WASp-mediated actin polymerization in living cells.

Journal: Molecular cell20091113

Title: Characterization of a novel focal adhesion kinase inhibitor in human platelets.

Journal: Biochemical and biophysical research communications20091106

Title: Embryogenesis: Degenerate phosphatases control the oocyte-to-embryo transition.

Journal: Current biology : CB20091103

Title: Recombinant human epidermal growth factor treatment of radiation-induced severe oral mucositis in patients with head and neck malignancies.

Journal: European journal of cancer care20091101

Title: The interaction of estrogen receptor alpha and caveolin-3 regulates connexin43 phosphorylation in metabolic inhibition-treated rat cardiomyocytes.

Journal: The international journal of biochemistry & cell biology20091101

Title: Differential 14-3-3 affinity capture reveals new downstream targets of phosphatidylinositol 3-kinase signaling.

Journal: Molecular & cellular proteomics : MCP20091101

Title: Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex.

Journal: The Biochemical journal20091101

Title: Nutrient stress activates inflammation and reduces glucose metabolism by suppressing AMP-activated protein kinase in the heart.

Journal: Diabetes20091101

Title: Proteomic, functional and motif-based analysis of C-terminal Src kinase-interacting proteins.

Journal: Proteomics20091101

Title: Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3.

Journal: Carcinogenesis20091101

Title: STEAP4 regulates focal adhesion kinase activation and CpG motifs within STEAP4 promoter region are frequently methylated in DU145, human androgen-independent prostate cancer cells.

Journal: International journal of molecular medicine20091101

Title: Impaired fibroblast growth factor receptor 1 signaling as a cause of normosmic idiopathic hypogonadotropic hypogonadism.

Journal: The Journal of clinical endocrinology and metabolism20091101

Title: FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.

Journal: Journal of immunology (Baltimore, Md. : 1950)20091101

Title: Phosphoinositide 3-kinase-regulated adapters in lymphocyte activation.

Journal: Immunological reviews20091101

Title: Differential expression of CD3zeta message and protein in tumor infiltrating lymphocytes from solid tumor specimens and malignant ascites from patients with ovarian carcinoma.

Journal: Anticancer research20091101

Title: Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts.

Journal: Blood20091029

Title: PTEN and SHIP2 regulates PI3K/Akt pathway through focal adhesion kinase.

Journal: Molecular and cellular endocrinology20091015

Title: Sam68 and ERKs regulate leptin-induced expression of OB-Rb mRNA in C2C12 myotubes.

Journal: Molecular and cellular endocrinology20091015

Title: fps/fes knockout mice display a lactation defect and the fps/fes tyrosine kinase is a component of E-cadherin-based adherens junctions in breast epithelial cells during lactation.

Journal: Experimental cell research20091015

Title: Developmental switch in NF-kappaB signalling required for neurite growth.

Journal: Development (Cambridge, England)20091015

Title: Tyrosine phosphorylation of nuclear-membrane protein emerin by Src, Abl and other kinases.

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Title: A nuclear localization signal at the SAM-SAM domain interface of AIDA-1 suggests a requirement for domain uncoupling prior to nuclear import.

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Title: Effects of VEGFR-3 phosphorylation inhibitor on lymph node metastasis in an orthotopic diffuse-type gastric carcinoma model.

Journal: British journal of cancer20091006

Title: Tyrosine phosphorylation of neuronal nitric oxide synthase (nNOS) during hypoxia in the cerebral cortex of newborn piglets: the role of nitric oxide.

Journal: Neuroscience letters20091002

Title: Semaphorin3A signaling mediated by Fyn-dependent tyrosine phosphorylation of collapsin response mediator protein 2 at tyrosine 32.

Journal: The Journal of biological chemistry20091002

Title: A new role of anandamide in human sperm: focus on metabolism.

Journal: Journal of cellular physiology20091001

Title: Atypical protein kinase C activity is required for extracellular matrix degradation and invasion by Src-transformed cells.

Journal: Journal of cellular physiology20091001

Title: Increased MAPK activation and impaired insulin signaling in subcutaneous microvascular endothelial cells in type 2 diabetes: the role of endothelin-1.

Journal: Diabetes20091001

Title: Proteomic analysis of integrin alphaIIbbeta3 outside-in signaling reveals Src-kinase-independent phosphorylation of Dok-1 and Dok-3 leading to SHIP-1 interactions.

Journal: Journal of thrombosis and haemostasis : JTH20091001

Title: Essential involvement of the NMDA receptor in ethanol preconditioning-dependent neuroprotection from amyloid-betain vitro.

Journal: Journal of neurochemistry20091001

Title: Involvement of protein kinase C and Src tyrosine kinase in acute tolerance to ethanol inhibition of spinal NMDA-induced pressor responses in rats.

Journal: British journal of pharmacology20091001

Title: Amyloid precursor family proteins are expressed by thymic and lymph node stromal cells but are not required for lymphocyte development.

Journal: International immunology20091001

Title: Brassinosteroid signal transduction from cell-surface receptor kinases to nuclear transcription factors.

Journal: Nature cell biology20091001

Title: Is expression or activation of Src kinase associated with cancer-specific survival in ER-, PR- and HER2-negative breast cancer patients?

Journal: The American journal of pathology20091001

Title: Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells.

Journal: PLoS pathogens20091001

Title: Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM10.

Journal: PLoS biology20091001

Title: Positive selection of tyrosine loss in metazoan evolution.

Journal: Science (New York, N.Y.)20090925

Title: Crystal structures of Wzb of Escherichia coli and CpsB of Streptococcus pneumoniae, representatives of two families of tyrosine phosphatases that regulate capsule assembly.

Journal: Journal of molecular biology20090925

Title: New activation modus of STAT3: a tyrosine-less region of the interleukin-22 receptor recruits STAT3 by interacting with its coiled-coil domain.

Journal: The Journal of biological chemistry20090925

Title: Peptide-major histocompatibility complex dimensions control proximal kinase-phosphatase balance during T cell activation.

Journal: The Journal of biological chemistry20090918

Title: Dopamine regulates phosphorylation of VEGF receptor 2 by engaging Src-homology-2-domain-containing protein tyrosine phosphatase 2.

Journal: Journal of cell science20090915

Title: VEGFR2-PLCgamma1 axis is essential for endothelial specification of VEGFR2+ vascular progenitor cells.

Journal: Journal of cell science20090915

Title: Increased protein stability of FGF1 can compensate for its reduced affinity for heparin.

Journal: The Journal of biological chemistry20090911

Title: Lithium suppresses motility and invasivity of v-src-transformed cells by glutathione-dependent activation of phosphotyrosine phosphatases.

Journal: Oncogene20090910

Title: CCM2 mediates death signaling by the TrkA receptor tyrosine kinase.

Journal: Neuron20090910

Title: Post-transcriptional regulation of chemokine receptor CXCR4 by estrogen in HER2 overexpressing, estrogen receptor-positive breast cancer cells.

Journal: Breast cancer research and treatment20090901

Title: Enhanced ex vivo expansion of human adipose tissue-derived mesenchymal stromal cells by fibroblast growth factor-2 and dexamethasone.

Journal: Tissue engineering. Part A20090901

Title: Detection and analysis of protein histidine phosphorylation.

Journal: Molecular and cellular biochemistry20090901

Title: Novel phosphotyrosine targets of FGFR2IIIb signaling.

Journal: Cellular signalling20090901

Title: Expression of full-length and truncated Fyn tyrosine kinase transcripts and encoded proteins during spermatogenesis and localization during acrosome biogenesis and fertilization.

Journal: Molecular reproduction and development20090901

Title: Growth hormone deficiency and antipituitary antibodies in a patient with common variable immunodeficiency.

Journal: Journal of endocrinological investigation20090901

Title: Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041.

Journal: Molecular & cellular proteomics : MCP20090901

Title: SH2B1 enhances insulin sensitivity by both stimulating the insulin receptor and inhibiting tyrosine dephosphorylation of insulin receptor substrate proteins.

Journal: Diabetes20090901

Title: Phosphorylation and consequent stimulation of the tyrosine kinase c-Abl by PKA in mouse spermatozoa; its implications during capacitation.

Journal: Developmental biology20090901

Title: Mirk/Dyrk1B, a novel therapeutic target, mediates cell survival in non-small cell lung cancer cells.

Journal: Cancer biology & therapy20090901

Title: Tyrosine-phosphorylation of the 12th armadillo-repeat of beta-catenin is associated with cadherin dysfunction in human cancer.

Journal: International journal of oncology20090901

Title: Group B Streptococcus induces tyrosine phosphorylation of annexin V and glutathione S-transferase in human umbilical vein endothelial cells.

Journal: International journal of molecular medicine20090901

Title: CD137 ligand-mediated reverse signals increase cell viability and cytokine expression in murine myeloid cells: involvement of mTOR/p70S6 kinase and Akt.

Journal: European journal of immunology20090901

Title: Differential regulation of type I interferon and epidermal growth factor pathways by a human Respirovirus virulence factor.

Journal: PLoS pathogens20090901

Title: Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse.

Journal: Proceedings of the National Academy of Sciences of the United States of America20090825

Title: Solid-phase synthesis of amino- and carboxyl-functionalized unnatural alpha-amino acid amides.

Journal: Organic letters20090820

Title: Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signalling.

Journal: The EMBO journal20090819

Title: Out of the box binding determines specificity of SH2 domain interaction.

Journal: Structure (London, England : 1993)20090812

Title: The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site.

Journal: Cell20090807

Title: Synthesis of phosphatase-stable, cell-permeable peptidomimetic prodrugs that target the SH2 domain of Stat3.

Journal: Organic letters20090806

Title: Determination of AMP-activated protein kinase phosphorylation sites in recombinant protein expressed using the pET28a vector: a cautionary tale.

Journal: Protein expression and purification20090801

Title: Oleoylethanolamide, a natural ligand for PPAR-alpha, inhibits insulin receptor signalling in HTC rat hepatoma cells.

Journal: Biochimica et biophysica acta20090801

Title: Vaccinia-induced epidermal growth factor receptor-MEK signalling and the anti-apoptotic protein F1L synergize to suppress cell death during infection.

Journal: Cellular microbiology20090801

Title: The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast cancer invasion and metastasis.

Journal: Traffic (Copenhagen, Denmark)20090801

Title: Systems-wide analysis of a phosphatase knock-down by quantitative proteomics and phosphoproteomics.

Journal: Molecular & cellular proteomics : MCP20090801

Title: Early effects of high glucose in retinal tissue cultures Renin-Angiotensin system-dependent and -independent signaling.

Journal: Neurobiology of disease20090801

Title: Defects in cell spreading and ERK1/2 activation in fibroblasts with lamin A/C mutations.

Journal: Biochimica et biophysica acta20090801

Title: Differential effects of EGFR ligands on endocytic sorting of the receptor.

Journal: Traffic (Copenhagen, Denmark)20090801

Title: An extensive survey of tyrosine phosphorylation revealing new sites in human mammary epithelial cells.

Journal: Journal of proteome research20090801

Title: Fibroblast growth factor receptor-1 phosphorylation requirement for cardiomyocyte differentiation in murine embryonic stem cells.

Journal: Journal of cellular and molecular medicine20090801

Title: Bidirectional regulation of insulin receptor autophosphorylation and kinase activity by peroxynitrite.

Journal: Archives of biochemistry and biophysics20090801

Title: pY-STAT3 and p53 expression predict outcome for poor prognosis diffuse large B-cell lymphoma treated with high dose chemotherapy and autologous stem cell transplantation.

Journal: Leukemia & lymphoma20090801

Title: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle.

Journal: The FEBS journal20090801

Title: Phosphorylation of the SSBP2 and ABL proteins by the ZNF198-FGFR1 fusion kinase seen in atypical myeloproliferative disorders as revealed by phosphopeptide-specific MS.

Journal: Proteomics20090801

Title: Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination.

Journal: Molecular cancer research : MCR20090801

Title: Cadherin-cadherin engagement promotes cell survival via Rac1/Cdc42 and signal transducer and activator of transcription-3.

Journal: Molecular cancer research : MCR20090801

Title: The Drosophila SH2B family adaptor Lnk acts in parallel to chico in the insulin signaling pathway.

Journal: PLoS genetics20090801

Title: Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.

Journal: PLoS pathogens20090801

Title: [Detection of phosphotyrosine in chronic myeloid leukemia cells with PY20 antibody and its clinical applications].

Journal: Zhongguo shi yan xue ye xue za zhi20090801

Title: Hierarchical modeling of activation mechanisms in the ABL and EGFR kinase domains: thermodynamic and mechanistic catalysts of kinase activation by cancer mutations.

Journal: PLoS computational biology20090801

Title: Identification of pY19-caveolin-2 as a positive regulator of insulin-stimulated actin cytoskeleton-dependent mitogenesis.

Journal: Journal of cellular and molecular medicine20090801

Title: Protein-tyrosine phosphatase-alpha and Src functionally link focal adhesions to the endoplasmic reticulum to mediate interleukin-1-induced Ca2+ signaling.

Journal: The Journal of biological chemistry20090731

Title: Regulation of the innate immune response by threonine-phosphatase of Eyes absent.

Journal: Nature20090723

Title: In vitro enzymatic characterization of near full length EGFR in activated and inhibited states.

Journal: Biochemistry20090721

Title: Selective detection of phosphotyrosine in the presence of various phosphate-containing biomolecules with the aid of a terbium(III) complex.

Journal: Chembiochem : a European journal of chemical biology20090720

Title: Dephosphorylation of major sperm protein (MSP) fiber protein 3 by protein phosphatase 2A during cell body retraction in the MSP-based amoeboid motility of Ascaris sperm.

Journal: Molecular biology of the cell20090715

Title: Regulation of process retraction and cell migration by EphA3 is mediated by the adaptor protein Nck1.

Journal: Biochemistry20090714

Title: Dasatinib synergizes with doxorubicin to block growth, migration, and invasion of breast cancer cells.

Journal: British journal of cancer20090707

Title: Quantitative immunohistochemical expression of c Kit in breast carcinomas is predictive of patients' outcome.

Journal: British journal of cancer20090707

Title: Prolectin, a glycan-binding receptor on dividing B cells in germinal centers.

Journal: The Journal of biological chemistry20090703

Title: Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/TCF-mediated transcription.

Journal: The Journal of biological chemistry20090703

Title: The importance of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kilodaltons sterile-alpha motif domain in thymic selection and T-cell activation.

Journal: Blood20090702

Title: Protein kinase C-Fyn kinase cascade mediates the oleic acid-induced disassembly of neonatal rat cardiomyocyte adherens junctions.

Journal: The international journal of biochemistry & cell biology20090701

Title: Signal transduction by CD58: the transmembrane isoform transmits signals outside lipid rafts independently of the GPI-anchored isoform.

Journal: Cellular signalling20090701

Title: Reciprocal regulation of Abl and receptor tyrosine kinases.

Journal: Cellular signalling20090701

Title: Phosphorylation of the activation loop tyrosines is required for sustained Syk signaling and growth factor-independent B-cell proliferation.

Journal: Cellular signalling20090701

Title: The phosphoproteome of bloodstream form Trypanosoma brucei, causative agent of African sleeping sickness.

Journal: Molecular & cellular proteomics : MCP20090701

Title: Purple acid phosphatase-like sequences in prokaryotic genomes and the characterization of an atypical purple alkaline phosphatase from Burkholderia cenocepacia J2315.

Journal: Gene20090701

Title: Regulation of colonic apical potassium (BK) channels by cAMP and somatostatin.

Journal: American journal of physiology. Gastrointestinal and liver physiology20090701

Title: Anthrax infection inhibits the AKT signaling involved in the E-cadherin-mediated adhesion of lung epithelial cells.

Journal: FEMS immunology and medical microbiology20090701

Title: Caveolin-2 regulation of STAT3 transcriptional activation in response to insulin.

Journal: Biochimica et biophysica acta20090701

Title: Fibrinogen binding to ICAM-1 promotes EGFR-dependent mucin production in human airway epithelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology20090701

Title: Quenched ligand-directed tosylate reagents for one-step construction of turn-on fluorescent biosensors.

Journal: Journal of the American Chemical Society20090701

Title: Setaria cervi dual specific phosphatase: characterization and its effect on eosinophil degranulation.

Journal: Parasitology20090701

Title: Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease.

Journal: Cancer research20090701

Title: Chemical genetics reveals bacterial and host cell functions critical for type IV effector translocation by Legionella pneumophila.

Journal: PLoS pathogens20090701

Title: Response prediction to a multitargeted kinase inhibitor in cancer cell lines and xenograft tumors using high-content tyrosine peptide arrays with a kinetic readout.

Journal: Molecular cancer therapeutics20090701

Title: Spectroscopic characterization of the SH2- and active site-directed peptide sequences of a bivalent Src kinase inhibitor.

Journal: Applied spectroscopy20090701

Title: Large-scale proteomic analysis of tyrosine-phosphorylation induced by T-cell receptor or B-cell receptor activation reveals new signaling pathways.

Journal: Proteomics20090701

Title: The Y's that bind: negative regulators of Src family kinase activity in platelets.

Journal: Journal of thrombosis and haemostasis : JTH20090701

Title: Numb-mediated neurite outgrowth is isoform-dependent, and requires activation of voltage-dependent calcium channels.

Journal: Neuroscience20090630

Title: Role of the IRS-1 and/or -2 in the pathogenesis of insulin resistance in Dahl salt-sensitive (S) rats.

Journal: Heart international20090630

Title: Ligand switching in cell-permeable peptides: manipulation of the alpha-integrin signature motif.

Journal: ACS chemical biology20090619

Title: Identification of a novel negative regulator of activin/nodal signaling in mesendodermal formation of Xenopus embryos.

Journal: The Journal of biological chemistry20090619

Title: Sennoside B inhibits PDGF receptor signaling and cell proliferation induced by PDGF-BB in human osteosarcoma cells.

Journal: Life sciences20090619

Title: Phosphoproteomic analysis of Syk kinase signaling in human cancer cells reveals its role in cell-cell adhesion.

Journal: Oncogene20090618

Title: Evidence for convergent evolution in the signaling properties of a choanoflagellate tyrosine kinase.

Journal: Biochemistry20090616

Title: Oxidative stress induces lipid-raft-mediated activation of Src homology 2 domain-containing protein-tyrosine phosphatase 2 in astrocytes.

Journal: Free radical biology & medicine20090615

Title: Anaplastic lymphoma kinase: signalling in development and disease.

Journal: The Biochemical journal20090615

Title: Steel factor enhances supraoptimal antigen-induced IL-6 production from mast cells via activation of protein kinase C-beta.

Journal: Journal of immunology (Baltimore, Md. : 1950)20090615

Title: PTPRR protein tyrosine phosphatase isoforms and locomotion of vesicles and mice.

Journal: Cerebellum (London, England)20090601

Title: Angiotensin-(1-7) activates a tyrosine phosphatase and inhibits glucose-induced signalling in proximal tubular cells.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20090601

Title: Connective tissue growth factor(CCN2), a pathogenic factor in diabetic nephropathy. What does it do? How does it do it?

Journal: Journal of cell communication and signaling20090601

Title: Glycogen synthase kinase-3 promotes the synergistic action of interferon-gamma on lipopolysaccharide-induced IL-6 production in RAW264.7 cells.

Journal: Cellular signalling20090601

Title: Inhibition of insulin-stimulated hydrogen peroxide production prevents stimulation of sodium transport in A6 cell monolayers.

Journal: American journal of physiology. Renal physiology20090601

Title: Inhibition of Src activity decreases tyrosine phosphorylation of occludin in brain capillaries and attenuates increase in permeability of the blood-brain barrier after transient focal cerebral ischemia.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism20090601

Title: Gas-phase intramolecular phosphate shift in phosphotyrosine-containing peptide monoanions.

Journal: Analytical chemistry20090601

Title: Negative ion fragmentations of deprotonated peptides containing post-translational modifications. An unusual cyclisation/rearrangement involving phosphotyrosine; a joint experimental and theoretical study.

Journal: Rapid communications in mass spectrometry : RCM20090601

Title: Revisiting histidine-dependent acid phosphatases: a distinct group of tyrosine phosphatases.

Journal: Trends in biochemical sciences20090601

Title: [In vitro capacitation].

Journal: Gynecologie, obstetrique & fertilite20090601

Title: Dok-4 is a novel negative regulator of T cell activation.

Journal: Journal of immunology (Baltimore, Md. : 1950)20090601

Title: Cross-talk between TLR4 and FcgammaReceptorIII (CD16) pathways.

Journal: PLoS pathogens20090601

Title: Direct binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesis.

Journal: PLoS biology20090601

Title: A sensitive magnetic bead method for the detection and identification of tyrosine phosphorylation in proteins by MALDI-TOF/TOF MS.

Journal: Proteomics20090601

Title: Connecting quorum sensing, c-di-GMP, pel polysaccharide, and biofilm formation in Pseudomonas aeruginosa through tyrosine phosphatase TpbA (PA3885).

Journal: PLoS pathogens20090601

Title: P66Shc signals to age.

Journal: Aging20090601

Title: The structure of an interdomain complex that regulates talin activity.

Journal: The Journal of biological chemistry20090529

Title: Density-enhanced phosphatase 1 regulates phosphorylation of tight junction proteins and enhances barrier function of epithelial cells.

Journal: The Journal of biological chemistry20090529

Title: Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria.

Journal: The Journal of biological chemistry20090529

Title: Phospholipase D-mediated activation of IQGAP1 through Rac1 regulates hyperoxia-induced p47phox translocation and reactive oxygen species generation in lung endothelial cells.

Journal: The Journal of biological chemistry20090529

Title: Structure and in vivo requirement of the yeast Spt6 SH2 domain.

Journal: Journal of molecular biology20090529

Title: Cucurbitane-type triterpenoids from the stems of Cucumis melo.

Journal: Journal of natural products20090522

Title: Src supports UDP-glucuronosyltransferase-2B7 detoxification of catechol estrogens associated with breast cancer.

Journal: Biochemical and biophysical research communications20090515

Title: Discovery of thioether-bridged cyclic pentapeptides binding to Grb2-SH2 domain with high affinity.

Journal: Bioorganic & medicinal chemistry letters20090515

Title: The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis.

Journal: Blood20090514

Title: FAK mediates the inhibition of glioma cell migration by truncated 24 kDa FGF-2.

Journal: Biochemical and biophysical research communications20090508

Title: Purinergic regulation of vascular endothelial growth factor signaling in angiogenesis.

Journal: British journal of cancer20090505

Title: Regulation of macrophage nitric oxide production by the protein tyrosine phosphatase Src homology 2 domain phosphotyrosine phosphatase 1 (SHP-1).

Journal: Immunology20090501

Title: Enhanced clonogenic survival induced by protein tyrosine phosphatase (PTP) inhibition after Cr(VI) exposure is mediated by c-Raf and Ras activity.

Journal: Cellular signalling20090501

Title: In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation.

Journal: DNA repair20090501

Title: 14-3-3:Shc scaffolds integrate phosphoserine and phosphotyrosine signaling to regulate phosphatidylinositol 3-kinase activation and cell survival.

Journal: The Journal of biological chemistry20090501

Title: Interaction of Mint2 with TrkA is involved in regulation of nerve growth factor-induced neurite outgrowth.

Journal: The Journal of biological chemistry20090501

Title: Targeted disruption of ROCK1 causes insulin resistance in vivo.

Journal: The Journal of biological chemistry20090501

Title: Systematic LC-MS analysis of labile post-translational modifications in complex mixtures.

Journal: Journal of proteome research20090501

Title: Bacteria-induced uroplakin signaling mediates bladder response to infection.

Journal: PLoS pathogens20090501

Title: A structure-based approach for detection of thiol oxidoreductases and their catalytic redox-active cysteine residues.

Journal: PLoS computational biology20090501

Title: Peroxynitrite signaling in human erythrocytes: synergistic role of hemoglobin oxidation and band 3 tyrosine phosphorylation.

Journal: Archives of biochemistry and biophysics20090415

Title: Visualizing immune system complexity.

Journal: Science signaling20090414

Title: Presenilin 1 affects focal adhesion site formation and cell force generation via c-Src transcriptional and posttranslational regulation.

Journal: The Journal of biological chemistry20090410

Title: Annexin 2 has a dual role as regulator and effector of v-Src in cell transformation.

Journal: The Journal of biological chemistry20090410

Title: Aggregation of membrane proteins by cytosolic cross-linkers: theory and simulation of the LAT-Grb2-SOS1 system.

Journal: Biophysical journal20090408

Title: Inappropriate activation of cyclin-dependent kinases by the phosphatase Cdc25b results in premature mitotic entry and triggers a p53-dependent checkpoint.

Journal: The Journal of biological chemistry20090403

Title: Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain.

Journal: Journal of molecular biology20090403

Title: Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions.

Journal: Nature20090402

Title: DNA repair: New tales of an old tail.

Journal: Nature20090402

Title: Epidermal growth factor receptors: function modulation by phosphorylation and glycosylation interplay.

Journal: Molecular biology reports20090401

Title: From immune response to cancer: a spot on the low molecular weight protein tyrosine phosphatase.

Journal: Cellular and molecular life sciences : CMLS20090401

Title: Cloning, expression, purification and functional characterization of the oligomerization domain of Bcr-Abl oncoprotein fused to the cytoplasmic transduction peptide.

Journal: Protein expression and purification20090401

Title: Identification and characterization of neuronal mitogen-activated protein kinase substrates using a specific phosphomotif antibody.

Journal: Molecular & cellular proteomics : MCP20090401

Title: Phosphotyrosine-dependent in vitro reconstitution of recombinant LAT-nucleated multiprotein signalling complexes on liposomes.

Journal: Molecular membrane biology20090401

Title: Beta-Cell hyperplasia induced by hepatic insulin resistance: role of a liver-pancreas endocrine axis through insulin receptor A isoform.

Journal: Diabetes20090401

Title: The mixed-lineage kinase DLK undergoes Src-dependent tyrosine phosphorylation and activation in cells exposed to vanadate or platelet-derived growth factor (PDGF).

Journal: Cellular signalling20090401

Title: Identification and specific localization of tyrosine-phosphorylated proteins in Trypanosoma brucei.

Journal: Eukaryotic cell20090401

Title: Phosphorylation of the amino-terminal region of X11L regulates its interaction with APP.

Journal: Journal of neurochemistry20090401

Title: Mitochondrial diacylglycerol initiates protein-kinase D1-mediated ROS signaling.

Journal: Journal of cell science20090401

Title: Endocytosis of flotillin-1 and flotillin-2 is regulated by Fyn kinase.

Journal: Journal of cell science20090401

Title: Kinome signaling through regulated protein-protein interactions in normal and cancer cells.

Journal: Current opinion in cell biology20090401

Title: Tyrosine phosphoproteome of hamster spermatozoa: role of glycerol-3-phosphate dehydrogenase 2 in sperm capacitation.

Journal: Proteomics20090401

Title: Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling.

Journal: PLoS computational biology20090401

Title: Role of H(2)O(2)-activated TRPM2 calcium channel in oxidant-induced endothelial injury.

Journal: Thrombosis and haemostasis20090401

Title: A bipolar clamp mechanism for activation of Jak-family protein tyrosine kinases.

Journal: PLoS computational biology20090401

Title: Current Screens Based on the AlphaScreen Technology for Deciphering Cell Signalling Pathways.

Journal: Current genomics20090401

Title: Association of constitutively activated hepatocyte growth factor receptor (Met) with resistance to a dual EGFR/Her2 inhibitor in non-small-cell lung cancer cells.

Journal: British journal of cancer20090324

Title: Time-dependent effects of imatinib in human leukaemia cells: a kinetic NMR-profiling study.

Journal: British journal of cancer20090324

Title: Radiosensitisation of U87MG brain tumours by anti-epidermal growth factor receptor monoclonal antibodies.

Journal: British journal of cancer20090324

Title: The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL.

Journal: Blood20090319

Title: The Salmonella effector SptP dephosphorylates host AAA+ ATPase VCP to promote development of its intracellular replicative niche.

Journal: Cell host & microbe20090319

Title: Molecular dynamics simulations reveal that Tyr-317 phosphorylation reduces Shc binding affinity for phosphotyrosyl residues of epidermal growth factor receptor.

Journal: Biophysical journal20090318

Title: Automated metal-free multiple-column nanoLC for improved phosphopeptide analysis sensitivity and throughput.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20090315

Title: Dual-specificity phosphatases: critical regulators with diverse cellular targets.

Journal: The Biochemical journal20090315

Title: T-independent antibody responses to T-dependent antigens: a novel follicular dendritic cell-dependent activity.

Journal: Journal of immunology (Baltimore, Md. : 1950)20090315

Title: S100A13-C2A binary complex structure-a key component in the acidic fibroblast growth factor for the non-classical pathway.

Journal: Biochemical and biophysical research communications20090313

Title: Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation.

Journal: Structure (London, England : 1993)20090311

Title: Growth factors outside of the platelet-derived growth factor (PDGF) family employ reactive oxygen species/Src family kinases to activate PDGF receptor alpha and thereby promote proliferation and survival of cells.

Journal: The Journal of biological chemistry20090306

Title: Protein and lipid kinase inhibitors as targeted anticancer agents of the Ras/Raf/MEK and PI3K/PKB pathways.

Journal: Purinergic signalling20090301

Title: Proteomics study of medullary thyroid carcinomas expressing RET germ-line mutations: identification of new signaling elements.

Journal: Molecular carcinogenesis20090301

Title: Binding specificity of SH2 domains: insight from free energy simulations.

Journal: Proteins20090301

Title: The phosphotyrosine interactome of the insulin receptor family and its substrates IRS-1 and IRS-2.

Journal: Molecular & cellular proteomics : MCP20090301

Title: Leptin but not ciliary neurotrophic factor (CNTF) induces phosphotyrosine phosphatase-1B expression in human neuronal cells (SH-SY5Y): putative explanation of CNTF efficacy in leptin-resistant state.

Journal: Endocrinology20090301

Title: Diabetes reduces autophosphorylation of retinal insulin receptor and increases protein-tyrosine phosphatase-1B activity.

Journal: Investigative ophthalmology & visual science20090301

Title: A PPM-family protein phosphatase from the thermoacidophile Thermoplasma volcanium hydrolyzes protein-bound phosphotyrosine.

Journal: Extremophiles : life under extreme conditions20090301

Title: Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress.

Journal: Diabetes20090301

Title: The current state of proteomics in GI oncology.

Journal: Digestive diseases and sciences20090301

Title: Two related cases of type A insulin resistance with compound heterozygous mutations of the insulin receptor gene.

Journal: Diabetes research and clinical practice20090301

Title: Role of nonreceptor protein tyrosine kinases during phospholipase C-gamma 1-related uterine contractions in the rat.

Journal: Reproductive sciences (Thousand Oaks, Calif.)20090301

Title: The beta-catenin axis integrates multiple signals downstream from RET/papillary thyroid carcinoma leading to cell proliferation.

Journal: Cancer research20090301

Title: Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms.

Journal: Molecular bioSystems20090301

Title: Molecular imaging of Bcr-Abl phosphokinase in a xenograft model.

Journal: Molecular cancer therapeutics20090301

Title: The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T cell antigen receptor signaling.

Journal: PLoS pathogens20090301

Title: Regulation of embryonic cell adhesion by the prion protein.

Journal: PLoS biology20090301

Title: Regulation of focal adhesion turnover by ErbB signalling in invasive breast cancer cells.

Journal: British journal of cancer20090224

Title: Neurotrophin receptor activation and expression in human postmortem brain: effect of suicide.

Journal: Biological psychiatry20090215

Title: A HIF-1alpha-dependent autocrine feedback loop promotes survival of serum-deprived prostate cancer cells.

Journal: The Prostate20090215

Title: Transcription factor TFII-I causes transcriptional upregulation of GRP78 synthesis in prostate cancer cells.

Journal: Journal of cellular biochemistry20090215

Title: Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation.

Journal: The Journal of biological chemistry20090213

Title: Cross-linking of FcepsilonRI causes Ca2+ mobilization via a sphingosine kinase pathway in a clathrin-dependent manner.

Journal: Cell calcium20090201

Title: Temporal perturbation of tyrosine phosphoproteome dynamics reveals the system-wide regulatory networks.

Journal: Molecular & cellular proteomics : MCP20090201

Title: Grp94 is Tyr-phosphorylated by Fyn in the lumen of the endoplasmic reticulum and translocates to Golgi in differentiating myoblasts.

Journal: Biochimica et biophysica acta20090201

Title: Structural insights into the inhibited states of the Mer receptor tyrosine kinase.

Journal: Journal of structural biology20090201

Title: Role of initial protein phosphorylation events and localized release-activated calcium influx in B cell antigen receptor signaling.

Journal: Journal of leukocyte biology20090201

Title: PKCdelta-dependent functional switch of rpS3 between translation and DNA repair.

Journal: Biochimica et biophysica acta20090201

Title: Signal transducer and activator of transcription 5 tyrosine phosphorylation for the diagnosis and monitoring of patients with severe combined immunodeficiency.

Journal: The Journal of allergy and clinical immunology20090201

Title: Differential ligand binding to a human cytomegalovirus chemokine receptor determines cell type-specific motility.

Journal: PLoS pathogens20090201

Title: Src kinase Hck association with the WASp and mDia1 cytoskeletal regulators promotes chemoattractant-induced Hck membrane targeting and activation in neutrophils.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire20090201

Title: [Expression and kinetic analysis of catalytic domain of protein tyrosine phosphatases SHP-1/SHP-2].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology20090201

Title: PKD2 interacts with Lck and regulates NFAT activity in T cells.

Journal: BMB reports20090131

Title: Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin.

Journal: British journal of cancer20090127

Title: Restriction of Src activity by Cullin-5.

Journal: Current biology : CB20090127

Title: Large-scale structural analysis of the classical human protein tyrosine phosphatome.

Journal: Cell20090123

Title: The junctional integrity of epithelial cells is modulated by Pseudomonas aeruginosa quorum sensing molecule through phosphorylation-dependent mechanisms.

Journal: Experimental cell research20090115

Title: Glutamate acting on N-methyl-D-aspartate receptors attenuates insulin-like growth factor-1 receptor tyrosine phosphorylation and its survival signaling properties in rat hippocampal neurons.

Journal: The Journal of biological chemistry20090109

Title: Involvement of Src tyrosine kinases (SFKs) and of focal adhesion kinase (FAK) in the injurious mechanism in rat primary neuronal cultures exposed to chemical ischemia.

Journal: Journal of molecular neuroscience : MN20090101

Title: ERK1/2 mediate wounding- and G-protein-coupled receptor ligands-induced EGFR activation via regulating ADAM17 and HB-EGF shedding.

Journal: Investigative ophthalmology & visual science20090101

Title: Tyrosine phosphorylation of insulin receptor substrates during ischemia/reperfusion-induced apoptosis in rat liver.

Journal: Langenbeck's archives of surgery20090101

Title: Flow cytometric assay of phosphotyrosine levels in Bcr-Abl-positive chronic myelogenous leukemias: a potential prognostic marker.

Journal: Annals of hematology20090101

Title: Enhancement of sperm-zona pellucida (ZP) binding capacity by activation of protein kinase A and C pathways in certain infertile men with defective sperm-ZP binding.

Journal: Human reproduction (Oxford, England)20090101

Title: Peroxynitrite-dependent activation of protein phosphatase type 2A mediates microvascular endothelial barrier dysfunction.

Journal: Cardiovascular research20090101

Title: Giardia lamblia: Characterization of ecto-phosphatase activities.

Journal: Experimental parasitology20090101

Title: APPL1: role in adiponectin signaling and beyond.

Journal: American journal of physiology. Endocrinology and metabolism20090101

Title: Dissociation of tau toxicity and phosphorylation: role of GSK-3beta, MARK and Cdk5 in a Drosophila model.

Journal: Human molecular genetics20090101

Title: Positively regulated glycerol/G3P-dependent Bacillus subtilis gene expression system based on anti-termination.

Journal: Journal of molecular microbiology and biotechnology20090101

Title: The counteradhesive proteins, thrombospondin 1 and SPARC/osteonectin, open the tyrosine phosphorylation-responsive paracellular pathway in pulmonary vascular endothelia.

Journal: Microvascular research20090101

Title: Hypoxia decreases insulin signaling pathways in adipocytes.

Journal: Diabetes20090101

Title: Detection of homo- or hetero-association of Doks by fluorescence resonance energy transfer in living cells.

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging20090101

Title: Antiplatelet activity of beta-carboline alkaloids from Perganum harmala: a possible mechanism through inhibiting PLCgamma2 phosphorylation.

Journal: Vascular pharmacology20090101

Title: WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity.

Journal: Nature20090101

Title: Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance.

Journal: BMC systems biology20090101

Title: Beta amyloid oligomers and fibrils stimulate differential activation of primary microglia.

Journal: Journal of neuroinflammation20090101

Title: Norrin attenuates protease-mediated death of transformed retinal ganglion cells.

Journal: Molecular vision20090101

Title: Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion.

Journal: BMC cancer20090101

Title: Identification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assay.

Journal: Molecular cancer therapeutics20090101

Title: Linear combinations of docking affinities explain quantitative differences in RTK signaling.

Journal: Molecular systems biology20090101

Title: The IpaC carboxyterminal effector domain mediates Src-dependent actin polymerization during Shigella invasion of epithelial cells.

Journal: PLoS pathogens20090101

Title: Brain-derived neurotrophic factor modulation of Kv1.3 channel is disregulated by adaptor proteins Grb10 and nShc.

Journal: BMC neuroscience20090101

Title: Preparation and Characterization of a Polyclonal Antibody against Brominated Protein.

Journal: Journal of clinical biochemistry and nutrition20090101

Title: Nck adapter proteins: functional versatility in T cells.

Journal: Cell communication and signaling : CCS20090101

Title: Olive tree wood phenolic compounds with human platelet antiaggregant properties.

Journal: Blood cells, molecules & diseases20090101

Title: The effect of the dual Src/Abl kinase inhibitor AZD0530 on Philadelphia positive leukaemia cell lines.

Journal: BMC cancer20090101

Title: Phosphorylation of a tyrosine in the amyloid-beta protein precursor intracellular domain inhibits Fe65 binding and signaling.

Journal: Journal of Alzheimer's disease : JAD20090101

Title: Characterization of new substrates targeted by Yersinia tyrosine phosphatase YopH.

Journal: PloS one20090101

Title: Sequence-based feature prediction and annotation of proteins.

Journal: Genome biology20090101

Title: Antigen receptor signaling in the rheumatic diseases.

Journal: Arthritis research & therapy20090101

Title: Interaction between O-GlcNAc modification and tyrosine phosphorylation of prohibitin: implication for a novel binary switch.

Journal: PloS one20090101

Title: Taurine and guanidinoethanesulfonic acid (GES) differentially affects the expression and phosphorylation of cellular proteins in C6 glial cells.

Journal: Advances in experimental medicine and biology20090101

Title: Identification of oxidative stress-induced tyrosine phosphorylated proteins by immunoprecipitation and mass spectrometry.

Journal: Methods in molecular biology (Clifton, N.J.)20090101

Title: Use of stable isotope labeling by amino acids in cell culture (SILAC) for phosphotyrosine protein identification and quantitation.

Journal: Methods in molecular biology (Clifton, N.J.)20090101

Title: SH2 domain binding to phosphopeptide ligands: potential for drug targeting.

Journal: Frontiers in bioscience (Landmark edition)20090101

Title: Ser/Thr/Tyr protein phosphorylation in the archaeon Halobacterium salinarum--a representative of the third domain of life.

Journal: PloS one20090101

Title: Chemical probes that competitively and selectively inhibit Stat3 activation.

Journal: PloS one20090101

Title: Early cellular signaling responses to axonal injury.

Journal: Cell communication and signaling : CCS20090101

Title: A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase.

Journal: PloS one20090101

Title: Impact of anti-inflammatory agents on the gene expression profile of stimulated human neutrophils: unraveling endogenous resolution pathways.

Journal: PloS one20090101

Title: The Drosophila cell adhesion molecule Neuroglian regulates Lissencephaly-1 localisation in circulating immunosurveillance cells.

Journal: BMC immunology20090101

Title: Proteomic analysis of phosphoproteins sensitive to a phosphatidylinositol 3-kinase inhibitor, ZSTK474, by using SELDI-TOF MS.

Journal: Proteome science20090101

Title: A DNA sequence directed mutual transcription regulation of HSF1 and NFIX involves novel heat sensitive protein interactions.

Journal: PloS one20090101

Title: HD-PTP is a catalytically inactive tyrosine phosphatase due to a conserved divergence in its phosphatase domain.

Journal: PloS one20090101

Title: FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4.

Journal: PloS one20090101

Title: Inflammation and tumor progression: a lesson from TNF-alpha-dependent FAK signaling in cholangiocarcinoma.

Journal: Methods in molecular biology (Clifton, N.J.)20090101

Title: Systems pharmacology and genome medicine: a future perspective.

Journal: Genome medicine20090101

Title: Systems-level interactions between insulin-EGF networks amplify mitogenic signaling.

Journal: Molecular systems biology20090101

Title: Rapid assessment of the effect of ciprofloxacin on chromosomal DNA from Escherichia coli using an in situ DNA fragmentation assay.

Journal: BMC microbiology20090101

Title: Tumoral prostate shows different expression pattern of somatostatin receptor 2 (SSTR2) and phosphotyrosine phosphatase SHP-1 (PTPN6) according to tumor progression.

Journal: Advances in urology20090101

Title: Analysis of the functional role of Toll-like receptor-4 tyrosine phosphorylation.

Journal: Methods in molecular biology (Clifton, N.J.)20090101

Title: Unc119 protects from Shigella infection by inhibiting the Abl family kinases.

Journal: PloS one20090101

Title: Activity-based protein profiling of protein tyrosine phosphatases.

Journal: Methods in molecular biology (Clifton, N.J.)20090101

Title: Modulation of bovine sperm signalling pathways: correlation between intracellular parameters and sperm capacitation and acrosome exocytosis.

Journal: Reproduction, fertility, and development20090101

Title: Cryopreservation affects bovine sperm intracellular parameters associated with capacitation and acrosome exocytosis.

Journal: Reproduction, fertility, and development20090101

Title: The calcium-sensing receptor regulates parathyroid hormone gene expression in transfected HEK293 cells.

Journal: BMC biology20090101

Title: Indirect recruitment of a CD40 signaling pathway in dendritic cells by B7-DC cross-linking antibody modulates T cell functions.

Journal: PloS one20090101

Title: Src, PKCalpha, and PKCdelta are required for alphavbeta3 integrin-mediated metastatic melanoma invasion.

Journal: Cell communication and signaling : CCS20090101

Title: Distinct phosphorylation requirements regulate cortactin activation by TirEPEC and its binding to N-WASP.

Journal: Cell communication and signaling : CCS20090101

Title: Interface analysis of the complex between ERK2 and PTP-SL.

Journal: PloS one20090101

Title: Interplay between the heterotrimeric G-protein subunits Galphaq and Galphai2 sets the threshold for chemotaxis and TCR activation.

Journal: BMC immunology20090101

Title: Crk and CrkL adaptor proteins: networks for physiological and pathological signaling.

Journal: Cell communication and signaling : CCS20090101

Title: Selective enrichment in phosphopeptides for the identification of phosphorylated mitochondrial proteins.

Journal: Methods in enzymology20090101

Title: Distinguishing mitochondrial inner membrane orientation of dual specific phosphatase 18 and 21.

Journal: Methods in enzymology20090101

Title: Revised Mimivirus major capsid protein sequence reveals intron-containing gene structure and extra domain.

Journal: BMC molecular biology20090101

Title: MP470, a novel receptor tyrosine kinase inhibitor, in combination with Erlotinib inhibits the HER family/PI3K/Akt pathway and tumor growth in prostate cancer.

Journal: BMC cancer20090101

Title: The -271 G>A polymorphism of kinase insert domain-containing receptor gene regulates its transcription level in patients with non-small cell lung cancer.

Journal: BMC cancer20090101

Title: Helicobacter pylori induces cancer cell motility independent of the c-Met receptor.

Journal: Journal of carcinogenesis20090101

Title: Avicin D: a protein reactive plant isoprenoid dephosphorylates Stat 3 by regulating both kinase and phosphatase activities.

Journal: PloS one20090101

Title: Deleted in liver cancer 1 (DLC1) utilizes a novel binding site for Tensin2 PTB domain interaction and is required for tumor-suppressive function.

Journal: PloS one20090101

Title: Replication of porcine circoviruses.

Journal: Virology journal20090101

Title: Erythropoietin down-regulates stem cell factor receptor (Kit) expression in the leukemic proerythroblast: role of Lyn kinase.

Journal: PloS one20090101

Title: Somatostatin and opioid receptors do not regulate proliferation or apoptosis of the human multiple myeloma U266 cells.

Journal: Journal of experimental & clinical cancer research : CR20090101

Title: Analysis of DNA relaxation and cleavage activities of recombinant Mycobacterium tuberculosis DNA topoisomerase I from a new expression and purification protocol.

Journal: BMC biochemistry20090101

Title: Fluorine-18 labeling of phosphopeptides: a potential approach for the evaluation of phosphopeptide metabolism in vivo.

Journal: Biopolymers20090101

Title: Molecular characterization of lung dysplasia induced by c-Raf-1.

Journal: PloS one20090101

Title: Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention.

Journal: BMC cancer20090101

Title: Expression and function of the insulin receptor substrate proteins in cancer.

Journal: Cell communication and signaling : CCS20090101

Title: Rapid insulin-dependent endocytosis of the insulin receptor by caveolae in primary adipocytes.

Journal: PloS one20090101

Title: Disassembly of shank and homer synaptic clusters is driven by soluble beta-amyloid(1-40) through divergent NMDAR-dependent signalling pathways.

Journal: PloS one20090101

Title: ERK2, but not ERK1, mediates acquired and 'de novo' resistance to imatinib mesylate: implication for CML therapy.

Journal: PloS one20090101

Title: Structure-function analysis of nucleolin and ErbB receptors interactions.

Journal: PloS one20090101

Title: Regulation of the physiological function and metabolism of AbetaPP by AbetaPP binding proteins.

Journal: Journal of Alzheimer's disease : JAD20090101

Title: Yersinia outer protein YopE affects the actin cytoskeleton in Dictyostelium discoideum through targeting of multiple Rho family GTPases.

Journal: BMC microbiology20090101

Title: The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains.

Journal: Molecular neurodegeneration20090101

Title: Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein.

Journal: BMC cell biology20090101

Title: PPAR-γ agonists and their effects on IGF-I receptor signaling: Implications for cancer.

Journal: PPAR research20090101

Title: Identification of pediatric septic shock subclasses based on genome-wide expression profiling.

Journal: BMC medicine20090101

Title: Structural models of human eEF1A1 and eEF1A2 reveal two distinct surface clusters of sequence variation and potential differences in phosphorylation.

Journal: PloS one20090101

Title: Cytosolic SYT/SS18 isoforms are actin-associated proteins that function in matrix-specific adhesion.

Journal: PloS one20090101

Title: Gonadotropin-releasing hormone (GnRH)-I and GnRH-II induce cell growth inhibition in human endometrial cancer cells: involvement of integrin beta3 and focal adhesion kinase.

Journal: Reproductive biology and endocrinology : RB&E20090101

Title: Vav links the T cell antigen receptor to the actin cytoskeleton and T cell activation independently of intrinsic Guanine nucleotide exchange activity.

Journal: PloS one20090101

Title: Are small GTPases signal hubs in sugar-mediated induction of fructan biosynthesis?

Journal: PloS one20090101

Title: Tyrosine phosphorylation in immune cells: direct and indirect effects on toll-like receptor-induced proinflammatory cytokine production.

Journal: Critical reviews in immunology20090101

Title: Fibronectin-replating experiment: procedure and analysis.

Journal: Folia biologica20090101

Title: Imatinib induces apoptosis by inhibiting PDGF- but not insulin-induced PI 3-kinase/Akt survival signaling in RGC-5 retinal ganglion cells.

Journal: Molecular vision20090101

Title: Prolactin signaling through the short isoform of the mouse prolactin receptor regulates DNA binding of specific transcription factors, often with opposite effects in different reproductive issues.

Journal: Reproductive biology and endocrinology : RB&E20090101

Title: Current available therapies and future directions in the treatment of malignant gliomas.

Journal: Biologics : targets & therapy20090101

Title: Maximum entropy reconstructions of dynamic signaling networks from quantitative proteomics data.

Journal: PloS one20090101

Title: STAT5 regulation of BCL10 parallels constitutive NFkappaB activation in lymphoid tumor cells.

Journal: Molecular cancer20090101

Title: Proteomic characterization of HIV-modulated membrane receptors, kinases and signaling proteins involved in novel angiogenic pathways.

Journal: Journal of translational medicine20090101

Title: Talking to chromatin: post-translational modulation of polycomb group function.

Journal: Epigenetics & chromatin20090101

Title: ApoE isoform-dependent changes in hippocampal synaptic function.

Journal: Molecular neurodegeneration20090101

Title: Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis.

Journal: Journal of molecular signaling20090101

Title: Function, regulation and pathological roles of the Gab/DOS docking proteins.

Journal: Cell communication and signaling : CCS20090101

Title: LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation.

Journal: PloS one20090101

Title: 2D proteome analysis initiates new insights on the Salmonella Typhimurium LuxS protein.

Journal: BMC microbiology20090101

Title: PSSA-2, a membrane-spanning phosphoprotein of Trypanosoma brucei, is required for efficient maturation of infection.

Journal: PloS one20090101

Title: Barrier-to-autointegration factor proteome reveals chromatin-regulatory partners.

Journal: PloS one20090101

Title: High sequence homology between protein tyrosine acid phosphatase from boar seminal vesicles and human prostatic acid phosphatase.

Journal: Acta biochimica Polonica20090101

Title: Gene expression profiling in cells with enhanced gamma-secretase activity.

Journal: PloS one20090101

Title: VEGFR1 activity modulates myeloid cell infiltration in growing lung metastases but is not required for spontaneous metastasis formation.

Journal: PloS one20090101

Title: SOCS2 influences LPS induced human monocyte-derived dendritic cell maturation.

Journal: PloS one20090101

Title: Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT.

Journal: PloS one20090101

Title: Locomotion guidance by extracellular matrix is adaptive and can be restored by a transient change in Ca2+ level.

Journal: PloS one20090101

Title: Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region.

Journal: PloS one20090101

Title: Tumor-shed PGE(2) impairs IL2Rgammac-signaling to inhibit CD4 T cell survival: regulation by theaflavins.

Journal: PloS one20090101

Title: Eps15: a multifunctional adaptor protein regulating intracellular trafficking.

Journal: Cell communication and signaling : CCS20090101

Title: A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice.

Journal: PloS one20090101

Title: Empirical Bayes analysis of quantitative proteomics experiments.

Journal: PloS one20090101

Title: Stretch activates human myometrium via ERK, caldesmon and focal adhesion signaling.

Journal: PloS one20090101

Title: Identification of tyrosine-phosphorylated proteins associated with metastasis and functional analysis of FER in human hepatocellular carcinoma cells.

Journal: BMC cancer20090101

Title: Molecular machines or pleiomorphic ensembles: signaling complexes revisited.

Journal: Journal of biology20090101

Title: Partially-supervised protein subclass discovery with simultaneous annotation of functional residues.

Journal: BMC structural biology20090101

Title: Rab11 helps maintain apical crumbs and adherens junctions in the Drosophila embryonic ectoderm.

Journal: PloS one20090101

Title: multiplierz: an extensible API based desktop environment for proteomics data analysis.

Journal: BMC bioinformatics20090101

Title: Hepatic gene expression profiling reveals protective responses in Atlantic salmon vaccinated against furunculosis.

Journal: BMC genomics20090101

Title: Gas6 and the receptor tyrosine kinase Axl in clear cell renal cell carcinoma.

Journal: PloS one20090101

Title: Fyn mediates leptin actions in the thymus of rodents.

Journal: PloS one20090101

Title: A concerted kinase interplay identifies PPARgamma as a molecular target of ghrelin signaling in macrophages.

Journal: PloS one20090101

Title: MALDI profiling of human lung cancer subtypes.

Journal: PloS one20090101

Title: Azithromycin suppresses interleukin-12p40 expression in lipopolysaccharide and interferon-gamma stimulated macrophages.

Journal: International journal of biological sciences20090101

Title: The presence of alpha-catenin in the VE-cadherin complex is required for efficient transendothelial migration of leukocytes.

Journal: International journal of biological sciences20090101

Title: Impact of biospecimens handling on biomarker research in breast cancer.

Journal: BMC cancer20090101

Title: Antiproliferative effect of exemestane in lung cancer cells.

Journal: Molecular cancer20090101

Title: PRL-3 promotes the motility, invasion, and metastasis of LoVo colon cancer cells through PRL-3-integrin beta1-ERK1/2 and-MMP2 signaling.

Journal: Molecular cancer20090101

Title: ERalpha increases expression and interacts with TERT in cataractous canine lens epithelial cells.

Journal: Molecular vision20090101

Title: Fluorescence resonance energy transfer (FRET)-based subcellular visualization of pathogen-induced host receptor signaling.

Journal: BMC biology20090101

Title: Insulin signaling pathways in a patient with insulin resistance of difficult management - a case report.

Journal: Diabetology & metabolic syndrome20090101

Title: A predictive phosphorylation signature of lung cancer.

Journal: PloS one20090101

Title: Aberrant trafficking of NSCLC-associated EGFR mutants through the endocytic recycling pathway promotes interaction with Src.

Journal: BMC cell biology20090101

Title: Transcriptomic response of the mycoparasitic fungus Trichoderma atroviride to the presence of a fungal prey.

Journal: BMC genomics20090101

Title: Sulfatides partition disabled-2 in response to platelet activation.

Journal: PloS one20090101

Title: Expression-based network biology identifies alteration in key regulatory pathways of type 2 diabetes and associated risk/complications.

Journal: PloS one20090101

Title: Molecular mechanism for human sperm chemotaxis mediated by progesterone.

Journal: PloS one20090101

Title: Integrating complex genomic datasets and tumour cell sensitivity profiles to address a 'simple' question: which patients should get this drug?

Journal: BMC medicine20090101

Title: Evidence that phosphatidylinositol 3-kinase is involved in sperm-induced tyrosine kinase signaling in Xenopus egg fertilization.

Journal: BMC developmental biology20090101

Title: Soluble iron modulates iron oxide particle-induced inflammatory responses via prostaglandin E(2 )synthesis: In vitro and in vivo studies.

Journal: Particle and fibre toxicology20090101

Title: Computational modeling of the EGFR network elucidates control mechanisms regulating signal dynamics.

Journal: BMC systems biology20090101

Title: Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions.

Journal: Molecular systems biology20090101

Title: An optimal protocol to analyze the rat spinal cord proteome.

Journal: Biomarker insights20090101

Title: The function of cortactin in the clustering of acetylcholine receptors at the vertebrate neuromuscular junction.

Journal: PloS one20090101

Title: Anomalous constitutive Src kinase activity promotes B lymphoma survival and growth.

Journal: Molecular cancer20090101

Title: Identification of four novel phosphorylation sites in estrogen receptor alpha: impact on receptor-dependent gene expression and phosphorylation by protein kinase CK2.

Journal: BMC biochemistry20090101

Title: Detection of R576 interleukin-4 receptor an allele gene, serum interleukin-4, and eosinophilic cationic protein in atopic dermatitis patients.

Journal: Indian journal of dermatology20090101

Title: Determinants Present in the Receptor Carboxy Tail Are Responsible for Differences in Subtype-Specific Coupling of beta-Adrenergic Receptors to Phosphoinositide 3-Kinase.

Journal: International journal of cell biology20090101

Title: Application of mass spectrometry-based proteomics for biomarker discovery in neurological disorders.

Journal: Annals of Indian Academy of Neurology20090101

Title: TOM1L is involved in a novel signaling pathway important for the IL-2 production in Jurkat T cells stimulated by CD3/CD28 co-ligation.

Journal: Mediators of inflammation20090101

Title: Multiple roles and therapeutic implications of Akt signaling in cancer.

Journal: OncoTargets and therapy20090101

Title: Role of tyrosine phosphorylation in the antioxidant effects of the p75 neurotrophin receptor.

Journal: Oxidative medicine and cellular longevity20090101

Title: Gene Expression and Serum Cytokine Profiling of Low Stage CLL Identify WNT/PCP, Flt-3L/Flt-3 and CXCL9/CXCR3 as Regulators of Cell Proliferation, Survival and Migration.

Journal: Human genomics and proteomics : HGP20090101

Title: Caspase 8 promotes peripheral localization and activation of Rab5.

Journal: The Journal of biological chemistry20081226

Title: Differential subcellular localization of insulin receptor substrates depends on C-terminal regions and importin beta.

Journal: Biochemical and biophysical research communications20081219

Title: G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2.

Journal: The Journal of biological chemistry20081219

Title: Remote changes in the dynamics of the phosphotyrosine-binding domain of insulin receptor substrate-1 induced by phosphopeptide binding.

Journal: Biochemistry20081216

Title: CH/pi hydrogen bonds determine the selectivity of the Src homology 2 domain to tyrosine phosphotyrosyl peptides: an ab initio fragment molecular orbital study.

Journal: Journal of computational chemistry20081201

Title: Structure, dynamics, and binding thermodynamics of the v-Src SH2 domain: implications for drug design.

Journal: Proteins20081201

Title: E-cadherin core fucosylation regulates nuclear beta-catenin accumulation in lung cancer cells.

Journal: Glycoconjugate journal20081201

Title: Parathyroid hormone-related protein (107-139) increases human osteoblastic cell survival by activation of vascular endothelial growth factor receptor-2.

Journal: Journal of cellular physiology20081201

Title: Role of src-family kinases in hypoxic vasoconstriction of rat pulmonary artery.

Journal: Cardiovascular research20081201

Title: Internalization of EGF receptor following lipid rafts disruption in keratinocytes is delayed and dependent on p38 MAPK activation.

Journal: Journal of cellular physiology20081201

Title: A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion.

Journal: Blood20081201

Title: A 32-kDa tyrosine-phosphorylated protein shows a protease-dependent increase in dead boar spermatozoa.

Journal: The Journal of reproduction and development20081201

Title: Differential roles for the adapters Gads and LAT in platelet activation by GPVI and CLEC-2.

Journal: Journal of thrombosis and haemostasis : JTH20081201

Title: Resistance to high-fat diet-induced obesity but exacerbated insulin resistance in mice overexpressing preadipocyte factor-1 (Pref-1): a new model of partial lipodystrophy.

Journal: Diabetes20081201

Title: Expression of Fer testis (FerT) tyrosine kinase transcript variants and distribution sites of FerT during the development of the acrosome-acroplaxome-manchette complex in rat spermatids.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists20081201

Title: Endothelial Src kinase regulates membrane recycling from the lateral border recycling compartment during leukocyte transendothelial migration.

Journal: European journal of immunology20081201

Title: The fission yeast meiotic checkpoint kinase Mek1 regulates nuclear localization of Cdc25 by phosphorylation.

Journal: Cell cycle (Georgetown, Tex.)20081201

Title: Specific blockade of VEGF and HER2 pathways results in greater growth inhibition of breast cancer xenografts that overexpress HER2.

Journal: Cell cycle (Georgetown, Tex.)20081201

Title: Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction.

Journal: PLoS genetics20081201

Title: Leishmania-induced IRAK-1 inactivation is mediated by SHP-1 interacting with an evolutionarily conserved KTIM motif.

Journal: PLoS neglected tropical diseases20081201

Title: Role of stress fibers and focal adhesions as a mediator for mechano-signal transduction in endothelial cells in situ.

Journal: Vascular health and risk management20081201

Title: Structural and functional characterization of the c-terminal domain of the ecdysteroid phosphate phosphatase from bombyx mori reveals a new enzymatic activity.

Journal: Biochemistry20081118

Title: Negative regulation of TCR signaling by linker for activation of X cells via phosphotyrosine-dependent and -independent mechanisms.

Journal: Journal of immunology (Baltimore, Md. : 1950)20081115

Title: Genistein stimulates myocardial contractility in guinea pigs by different subcellular mechanisms.

Journal: European journal of pharmacology20081112

Title: Inhibitory effect of HGF on invasiveness of aggressive MDA-MB231 breast carcinoma cells, and role of HDACs.

Journal: British journal of cancer20081104

Title: Extracellular alkaline phosphatase is a sensitive marker for cellular stimulation and exocytosis in heterotroph cell cultures of Chenopodium rubrum.

Journal: Journal of plant physiology20081101

Title: Insulin growth factor 1 receptor/PI3K/AKT survival pathway in outer segment membranes of rod photoreceptors.

Journal: Investigative ophthalmology & visual science20081101

Title: Protein kinase CK2 catalyzes tyrosine phosphorylation in mammalian cells.

Journal: Cellular signalling20081101

Title: Negative regulation of Jak2 by its auto-phosphorylation at tyrosine 913 via the Epo signaling pathway.

Journal: Cellular signalling20081101

Title: JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin.

Journal: Cellular signalling20081101

Title: Prostacyclin receptor-induced STAT3 phosphorylation in human erythroleukemia cells is mediated via Galpha(s) and Galpha(16) hybrid signaling.

Journal: Cellular signalling20081101

Title: ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling.

Journal: Cellular signalling20081101

Title: Protein tyrosine kinases and protein tyrosine phosphatases are involved in abscisic acid-dependent processes in Arabidopsis seeds and suspension cells.

Journal: Plant physiology20081101

Title: The RACK1 signal anchor protein from Trypanosoma brucei associates with eukaryotic elongation factor 1A: a role for translational control in cytokinesis.

Journal: Molecular microbiology20081101

Title: Hyaluronan-mediated leukocyte adhesion and dextran sulfate sodium-induced colitis are attenuated in the absence of signal transducer and activator of transcription 1.

Journal: The American journal of pathology20081101

Title: Quantitative phosphoproteomics--an emerging key technology in signal-transduction research.

Journal: Proteomics20081101

Title: Relationships between urinary inositol excretions and whole-body glucose tolerance and skeletal muscle insulin receptor phosphorylation.

Journal: Metabolism: clinical and experimental20081101

Title: Multiplex detection and identification of proteins on a PVDF membrane blocked with a synthetic polymer-based reagent.

Journal: Electrophoresis20081101

Title: A genetically hard-wired metabolic transcriptome in Plasmodium falciparum fails to mount protective responses to lethal antifolates.

Journal: PLoS pathogens20081101

Title: Contribution of natural inhibitors to the understanding of the PI3K/PDK1/PKB pathway in the insulin-mediated intracellular signaling cascade.

Journal: International journal of molecular sciences20081101

Title: Synthesis and utilization of chiral alpha-methylated alpha-amino acids with a carboxyalkyl side chain in the design of novel Grb2-SH2 peptide inhibitors free of phosphotyrosine.

Journal: Journal of medicinal chemistry20081023

Title: Adaptor protein Lnk associates with Tyr(568) in c-Kit.

Journal: The Biochemical journal20081015

Title: Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer.

Journal: British journal of cancer20081007

Title: Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor alpha (WSX-1).

Journal: Annals of the rheumatic diseases20081001

Title: Momordica charantia (bitter melon) reduces plasma apolipoprotein B-100 and increases hepatic insulin receptor substrate and phosphoinositide-3 kinase interactions.

Journal: The British journal of nutrition20081001

Title: Sex-steroid hormones and EGF signalling in breast and prostate cancer cells: targeting the association of Src with steroid receptors.

Journal: Steroids20081001

Title: Emerging roles for protein histidine phosphorylation in cellular signal transduction: lessons from the islet beta-cell.

Journal: Journal of cellular and molecular medicine20081001

Title: Structural and functional characterization of a novel phosphatase from the Arabidopsis thaliana gene locus At1g05000.

Journal: Proteins20081001

Title: Regulation of insulin receptor substrate-1 expression levels by caveolin-1.

Journal: Journal of cellular physiology20081001

Title: Tyrosine phosphorylation and Ras activation is required for hydrogen peroxide-mediated Raf-1 kinase activation.

Journal: Molecular and cellular biochemistry20081001

Title: Increased activity of the human sperm tyrosine kinase SRC by the cAMP-dependent pathway in the presence of calcium.

Journal: Biology of reproduction20081001

Title: Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes.

Journal: Blood20081001

Title: Both EGFR kinase and Src-related tyrosine kinases regulate human ether-à-go-go-related gene potassium channels.

Journal: Cellular signalling20081001

Title: Identification of a functional interaction between Kv4.3 channels and c-Src tyrosine kinase.

Journal: Biochimica et biophysica acta20081001

Title: Erythropoietin receptor-mediated Egr-1 activation: structural requirements and functional implications.

Journal: Cellular signalling20081001

Title: Integrin-associated protein association with SRC homology 2 domain containing tyrosine phosphatase substrate 1 regulates igf-I signaling in vivo.

Journal: Diabetes20081001

Title: Muscle-specific IRS-1 Ser->Ala transgenic mice are protected from fat-induced insulin resistance in skeletal muscle.

Journal: Diabetes20081001

Title: Analysis of the calcium-dependent regulation of proline-rich tyrosine kinase 2 by gonadotropin-releasing hormone.

Journal: Molecular endocrinology (Baltimore, Md.)20081001

Title: G-CSF stimulates Jak2-dependent Gab2 phosphorylation leading to Erk1/2 activation and cell proliferation.

Journal: Cellular signalling20081001

Title: Critical role of Lck in L-selectin signaling induced by sulfatides engagement.

Journal: Journal of leukocyte biology20081001

Title: The role of phosphorylated residues in peptide-peptide noncovalent complexes formation.

Journal: Journal of the American Society for Mass Spectrometry20081001

Title: Involvement of heparan sulfate proteoglycan in sensing hypotonic stress in bovine aortic endothelial cells.

Journal: Biochimica et biophysica acta20081001

Title: Effect of cryopreservation on phosphorylation state of proteins involved in sperm motility initiation in sea bream.

Journal: Cryobiology20081001

Title: N-Glycans in cancer progression.

Journal: Glycobiology20081001

Title: Stat3 contributes to resistance toward BCR-ABL inhibitors in a bone marrow microenvironment model of drug resistance.

Journal: Molecular cancer therapeutics20081001

Title: [Effect of a novel tyrosine kinase inhibitor HHGV678 on growth inhibition of Bcr-Abl wild type and IM-resistant cell lines in vitro].

Journal: Zhongguo shi yan xue ye xue za zhi20081001

Title: Organization of physical interactomes as uncovered by network schemas.

Journal: PLoS computational biology20081001

Title: Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism.

Journal: PLoS biology20081001

Title: Repetitive N-WASP-binding elements of the enterohemorrhagic Escherichia coli effector EspF(U) synergistically activate actin assembly.

Journal: PLoS pathogens20081001

Title: Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37.

Journal: Molecular cell20080926

Title: EphrinB2 induces tyrosine phosphorylation of NR2B via Src-family kinases during inflammatory hyperalgesia.

Journal: Neuroscience20080922

Title: Eyes absent proteins: characterization of substrate specificity and phosphatase activity of mutants associated with branchial, otic and renal anomalies.

Journal: Chembiochem : a European journal of chemical biology20080922

Title: The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality.

Journal: Immunity20080919

Title: Platelet-derived growth factor-alpha receptor activation is required for human cytomegalovirus infection.

Journal: Nature20080918

Title: Dual MET-EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer.

Journal: British journal of cancer20080916

Title: Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis.

Journal: The Journal of biological chemistry20080912

Title: Inadequate activation of the GTPase RhoA contributes to the lack of fibronectin matrix assembly in von Hippel-Lindau protein-defective renal cancer cells.

Journal: The Journal of biological chemistry20080905

Title: Identification of c-Src tyrosine kinase substrates using mass spectrometry and peptide microarrays.

Journal: Journal of proteome research20080905

Title: Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation.

Journal: Cell20080905

Title: Detection of circulating tumour cells in peripheral blood with an automated scanning fluorescence microscope.

Journal: British journal of cancer20080902

Title: Linear motif atlas for phosphorylation-dependent signaling.

Journal: Science signaling20080902

Title: Feto-maternal ACP1 activity ratio and intrauterine survival.

Journal: European journal of obstetrics, gynecology, and reproductive biology20080901

Title: Insights from the energetics of water binding at the domain-ligand interface of the Src SH2 domain.

Journal: Proteins20080901

Title: The equatorial subsegment in mammalian spermatozoa is enriched in tyrosine phosphorylated proteins.

Journal: Biology of reproduction20080901

Title: Abi1 gene silencing by short hairpin RNA impairs Bcr-Abl-induced cell adhesion and migration in vitro and leukemogenesis in vivo.

Journal: Carcinogenesis20080901

Title: Expression and tyrosine phosphorylation of Crk-associated substrate lymphocyte type (Cas-L) protein in human neutrophils.

Journal: Journal of cellular biochemistry20080901

Title: Cleavage of disulfide bonds in mouse spermatogenic cell-specific type 1 hexokinase isozyme is associated with increased hexokinase activity and initiation of sperm motility.

Journal: Biology of reproduction20080901

Title: Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics.

Journal: Molecular & cellular proteomics : MCP20080901

Title: Phosphorylation and kinetics of mammalian cytochrome c oxidase.

Journal: Molecular & cellular proteomics : MCP20080901

Title: Carcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolism.

Journal: Diabetes20080901

Title: A subset of signal transduction pathways is required for hippocampal growth cone collapse induced by ephrin-A5.

Journal: Developmental neurobiology20080901

Title: Somatostatin receptors 1, 2, and 5 cooperate in the somatostatin inhibition of C6 glioma cell proliferation in vitro via a phosphotyrosine phosphatase-eta-dependent inhibition of extracellularly regulated kinase-1/2.

Journal: Endocrinology20080901

Title: The effect of phosphorylation on the electron capture dissociation of peptide ions.

Journal: Journal of the American Society for Mass Spectrometry20080901

Title: Immunohistochemical assessment of protein phosphorylation state: the dream and the reality.

Journal: Histochemistry and cell biology20080901

Title: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver.

Journal: The FEBS journal20080901

Title: Pigment epithelium-derived factor (PEDF) ameliorates advanced glycation end product (AGE)-induced hepatic insulin resistance in vitro by suppressing Rac-1 activation.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme20080901

Title: Rats with monosodium glutamate-induced obesity and insulin resistance exhibit low expression of Galpha(i2) G-protein.

Journal: General physiology and biophysics20080901

Title: Talin depletion reveals independence of initial cell spreading from integrin activation and traction.

Journal: Nature cell biology20080901

Title: Therapeutic options in the management of acromegaly: focus on lanreotide Autogel.

Journal: Biologics : targets & therapy20080901

Title: Kinetic characterization of O-phospho-L-tyrosine phosphohydrolase activity of two fungal phytases.

Journal: Journal of agricultural and food chemistry20080827

Title: System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties.

Journal: Chemistry & biology20080825

Title: Phosphorylation of the Arp2/3 complex is necessary to nucleate actin filaments.

Journal: The Journal of cell biology20080825

Title: Crystal structure of the human Fe65-PTB1 domain.

Journal: The Journal of biological chemistry20080822

Title: Prosaposin is an AR-target gene and its neurotrophic domain upregulates AR expression and activity in prostate stromal cells.

Journal: Journal of cellular biochemistry20080815

Title: Tyrosine phosphorylation modifies protein kinase C delta-dependent phosphorylation of cardiac troponin I.

Journal: The Journal of biological chemistry20080815

Title: The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVH genes.

Journal: Blood20080815

Title: Genome wide analysis of pathogenic SH2 domain mutations.

Journal: Proteins20080801

Title: Regulation of phosphate homeostasis by the phosphatonins and other novel mediators.

Journal: Pediatric nephrology (Berlin, Germany)20080801

Title: TGF-beta inhibits prolactin-induced expression of beta-casein by a Smad3-dependent mechanism.

Journal: Journal of cellular biochemistry20080801

Title: Integrin activation in bovine placentomes and in caruncular epithelial cells isolated from pregnant cows.

Journal: Biology of reproduction20080801

Title: Protein tyrosine phosphatase receptor type Z dephosphorylates TrkA receptors and attenuates NGF-dependent neurite outgrowth of PC12 cells.

Journal: Journal of biochemistry20080801

Title: Impact of oxidative stress and peroxisome proliferator-activated receptor gamma coactivator-1alpha in hepatic insulin resistance.

Journal: Diabetes20080801

Title: JAK2, but not Src family kinases, is required for STAT, ERK, and Akt signaling in response to growth hormone in preadipocytes and hepatoma cells.

Journal: Molecular endocrinology (Baltimore, Md.)20080801

Title: Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells.

Journal: Molecular endocrinology (Baltimore, Md.)20080801

Title: Global impact of oncogenic Src on a phosphotyrosine proteome.

Journal: Journal of proteome research20080801

Title: TiO(2)-based phosphoproteomic analysis of the plasma membrane and the effects of phosphatase inhibitor treatment.

Journal: Journal of proteome research20080801

Title: The receptor phosphatase HmLAR2 collaborates with focal adhesion proteins in filopodial tips to control growth cone morphology.

Journal: Developmental biology20080801

Title: New roles for pyruvate kinase M2: working out the Warburg effect.

Journal: Trends in biochemical sciences20080801

Title: CaMK-II promotes focal adhesion turnover and cell motility by inducing tyrosine dephosphorylation of FAK and paxillin.

Journal: Cell motility and the cytoskeleton20080801

Title: Impaired tyrosine phosphorylation of membrane type 1-matrix metalloproteinase reduces tumor cell proliferation in three-dimensional matrices and abrogates tumor growth in mice.

Journal: Carcinogenesis20080801

Title: An enriching phosphotyrosine experience for Src substrates.

Journal: Journal of proteome research20080801

Title: The NDR/LATS family kinase Cbk1 directly controls transcriptional asymmetry.

Journal: PLoS biology20080801

Title: Phosphoinositide-3 kinase-Akt pathway controls cellular entry of Ebola virus.

Journal: PLoS pathogens20080801

Title: [Regulatory effects of Shc-related phosphotyrosine adaptor proteins on aging].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20080801

Title: The renin-angiotensin system and diabetes: an update.

Journal: Vascular health and risk management20080801

Title: Can systems biology understand pathway activation? Gene expression signatures as surrogate markers for understanding the complexity of pathway activation.

Journal: Current genomics20080801

Title: The PPLA motif of glycogen synthase kinase 3beta is required for interaction with Fe65.

Journal: Molecules and cells20080731

Title: A DFT study on the formation of a phosphohistidine intermediate in prostatic acid phosphatase.

Journal: Journal of the American Chemical Society20080730

Title: Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis.

Journal: Biochemistry20080729

Title: A high affinity hepatocyte growth factor-binding site in the immunoglobulin-like region of Met.

Journal: The Journal of biological chemistry20080725

Title: Mitogen-activated protein kinase phosphatase-1 represses c-Jun NH2-terminal kinase-mediated apoptosis via NF-kappaB regulation.

Journal: The Journal of biological chemistry20080725

Title: Capture of phosphopeptides using alpha-zirconium phosphate nanoplatelets.

Journal: Analytical chemistry20080715

Title: A re-examination of the difluoromethylenesulfonic acid group as a phosphotyrosine mimic for PTP1B inhibition.

Journal: Bioorganic & medicinal chemistry20080715

Title: A wide-ranging cellular response to UV damage of DNA.

Journal: Cell cycle (Georgetown, Tex.)20080715

Title: Context-dependent fluorescence detection of a phosphorylated tyrosine residue by a ribonucleopeptide.

Journal: Journal of the American Chemical Society20080709

Title: TLR-independent induction of human monocyte IL-1 by phosphoglycolipids from thermophilic bacteria.

Journal: Glycoconjugate journal20080701

Title: Organization of multiprotein complexes at cell-cell junctions.

Journal: Histochemistry and cell biology20080701

Title: CD44 mobilization in allogeneic dendritic cell-T cell immunological synapse plays a key role in T cell activation.

Journal: Journal of leukocyte biology20080701

Title: Glypican-3-mediated oncogenesis involves the Insulin-like growth factor-signaling pathway.

Journal: Carcinogenesis20080701

Title: Hyperglycemia-induced reactive oxygen species toxicity to endothelial cells is dependent on paracrine mediators.

Journal: Diabetes20080701

Title: SHPS-1/SIRP1alpha contributes to interleukin-6 signalling.

Journal: Cellular signalling20080701

Title: Focal adhesion kinase and beta1 integrin regulation of Na+, K+, 2Cl- cotransporter in osmosensing ion transporting cells of killifish, Fundulus heteroclitus.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology20080701

Title: The adaptor 3BP2 activates CD244-mediated cytotoxicity in PKC- and SAP-dependent mechanisms.

Journal: Molecular immunology20080701

Title: Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo.

Journal: American journal of physiology. Renal physiology20080701

Title: Phosphoprotein profiling by PA-GeLC-MS/MS.

Journal: Journal of proteome research20080701

Title: Role of the C-terminal SH3 domain and N-terminal tyrosine phosphorylation in regulation of Tim and related Dbl-family proteins.

Journal: Biochemistry20080701

Title: Immunoaffinity enrichments followed by mass spectrometric detection for studying global protein tyrosine phosphorylation.

Journal: Journal of proteome research20080701

Title: MEK1/2 induces STAT5-mediated germline transcription of the TCRgamma locus in response to IL-7R signaling.

Journal: Journal of immunology (Baltimore, Md. : 1950)20080701

Title: Tumor-induced suppressor of cytokine signaling 3 inhibits toll-like receptor 3 signaling in dendritic cells via binding to tyrosine kinase 2.

Journal: Cancer research20080701

Title: Insulin resistance associated to obesity: the link TNF-alpha.

Journal: Archives of physiology and biochemistry20080701

Title: Gain-of-function mutations in the extracellular domain of KIT are common in canine mast cell tumors.

Journal: Molecular cancer research : MCR20080701

Title: Intracellular signaling by Akt: bound to be specific.

Journal: Science signaling20080617

Title: CLEC9A is a novel activation C-type lectin-like receptor expressed on BDCA3+ dendritic cells and a subset of monocytes.

Journal: The Journal of biological chemistry20080613

Title: Post-translational regulation of the ERK phosphatase DUSP6/MKP3 by the mTOR pathway.

Journal: Oncogene20080612

Title: FGFR4 and its novel splice form in myogenic cells: Interplay of glycosylation and tyrosine phosphorylation.

Journal: Journal of cellular physiology20080601

Title: Src-Tyrosine kinases are major agents in mitochondrial tyrosine phosphorylation.

Journal: Journal of cellular biochemistry20080601

Title: Stable isotopic labeling by amino acids in cultured primary neurons: application to brain-derived neurotrophic factor-dependent phosphotyrosine-associated signaling.

Journal: Molecular & cellular proteomics : MCP20080601

Title: Identification of the molecular chaperone, heat shock protein 1 (chaperonin 10), in the reproductive tract and in capacitating spermatozoa in the male mouse.

Journal: Biology of reproduction20080601

Title: Characterization of the RET protooncogene transmembrane domain mutation S649L associated with nonaggressive medullary thyroid carcinoma.

Journal: European journal of endocrinology20080601

Title: GTP avoidance in Tetrahymena thermophila requires tyrosine kinase activity, intracellular calcium, NOS, and guanylyl cyclase.

Journal: Purinergic signalling20080601

Title: Impact of the FcgammaII-receptor on quartz uptake and inflammatory response by alveolar macrophages.

Journal: American journal of physiology. Lung cellular and molecular physiology20080601

Title: TCR-induced downregulation of protein tyrosine phosphatase PEST augments secondary T cell responses.

Journal: Molecular immunology20080601

Title: A quantitative study of the recruitment potential of all intracellular tyrosine residues on EGFR, FGFR1 and IGF1R.

Journal: Molecular bioSystems20080601

Title: The virus-like particles of a braconid endoparasitoid wasp, Meteorus pulchricornis, inhibit hemocyte spreading in its noctuid host, Pseudaletia separata.

Journal: Journal of insect physiology20080601

Title: Stem cell factor and its receptor, c-kit, are important for hepatocyte proliferation in wild-type and tumor necrosis factor receptor-1 knockout mice after 70% hepatectomy.

Journal: Surgery20080601

Title: Model-based hypothesis testing of key mechanisms in initial phase of insulin signaling.

Journal: PLoS computational biology20080601

Title: Inhibition of ZAP-70 kinase activity via an analog-sensitive allele blocks T cell receptor and CD28 superagonist signaling.

Journal: The Journal of biological chemistry20080530

Title: Activation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65.

Journal: The Journal of biological chemistry20080523

Title: Roles of Necl-5/poliovirus receptor and Rho-associated kinase (ROCK) in the regulation of transformation of integrin alpha(V)beta(3)-based focal complexes into focal adhesions.

Journal: The Journal of biological chemistry20080523

Title: Development of electrochemical calcium sensors by using silicon nanowires modified with phosphotyrosine.

Journal: Biosensors & bioelectronics20080515

Title: Somatostatin/somatostatin receptor signalling: phosphotyrosine phosphatases.

Journal: Molecular and cellular endocrinology20080514

Title: Substitution of pseudokinase domain residue Val-617 by large non-polar amino acids causes activation of JAK2.

Journal: The Journal of biological chemistry20080509

Title: TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia.

Journal: The Journal of biological chemistry20080509

Title: EML4-ALK fusion transcript is not found in gastrointestinal and breast cancers.

Journal: British journal of cancer20080506

Title: Identification of disulfide-linked dimers of the receptor tyrosine kinase DDR1.

Journal: The Journal of biological chemistry20080502

Title: LC/MS identification of 12 intracellular cytoskeletal and inflammatory proteins from monocytes adherent on surface-adsorbed fibronectin-derived peptides.

Journal: Journal of biomedical materials research. Part A20080501

Title: Insulin growth factor signaling mediates neuron-like differentiation of adipose-tissue-derived stem cells.

Journal: Differentiation; research in biological diversity20080501

Title: Targets of tyrosine nitration in diabetic rat retina.

Journal: Molecular & cellular proteomics : MCP20080501

Title: Ex vivo induction of mRNA in human whole blood as a new platform of drug and dietary supplement development.

Journal: Pharmaceutical research20080501

Title: Glycosylation of IgG B cell receptor (IgG BCR) in multiple myeloma: relationship between sialylation and the signal activity of IgG BCR.

Journal: Glycoconjugate journal20080501

Title: Allosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1.

Journal: Biochimica et biophysica acta20080501

Title: Endosomal NADPH oxidase regulates c-Src activation following hypoxia/reoxygenation injury.

Journal: The Biochemical journal20080501

Title: Ecto-phosphatase activity on the external surface of Rhodnius prolixus salivary glands: modulation by carbohydrates and Trypanosoma rangeli.

Journal: Acta tropica20080501

Title: Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts.

Journal: Nature cell biology20080501

Title: Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase.

Journal: Bioorganic & medicinal chemistry letters20080501

Title: Mercury-induced crystallization and SAD phasing of the human Fe65-PTB1 domain.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications20080501

Title: Overproduction, purification, crystallization and preliminary X-ray analysis of human Fe65-PTB2 in complex with the amyloid precursor protein intracellular domain.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications20080501

Title: The parasexual cycle in Candida albicans provides an alternative pathway to meiosis for the formation of recombinant strains.

Journal: PLoS biology20080501

Title: Identification of phosphotyrosyl proteins in vitreous humours of patients with vitreoretinal diseases by sodium dodecyl sulphate-polyacrylamide gel electrophoresis/Western blotting/matrix-assisted laser desorption time-of-flight mass spectrometry.

Journal: Annals of clinical biochemistry20080501

Title: A transgenic Drosophila model demonstrates that the Helicobacter pylori CagA protein functions as a eukaryotic Gab adaptor.

Journal: PLoS pathogens20080501

Title: Genome analysis of the unicellular green alga Chlamydomonas reinhardtii Indicates an ancient evolutionary origin for key pattern recognition and cell-signaling protein families.

Journal: Genetics20080501

Title: Raf activation is regulated by tyrosine 510 phosphorylation in Drosophila.

Journal: PLoS biology20080501

Title: Interplay between acid phosphatase and cysteine proteases in mediating vitellin degradation during early embryogenesis of Periplaneta americana.

Journal: Journal of insect physiology20080501

Title: The Bro1-related protein HD-PTP/PTPN23 is required for endosomal cargo sorting and multivesicular body morphogenesis.

Journal: Proceedings of the National Academy of Sciences of the United States of America20080429

Title: The mechanism of anti-platelet activity of davallialactone: involvement of intracellular calcium ions, extracellular signal-regulated kinase 2 and p38 mitogen-activated protein kinase.

Journal: European journal of pharmacology20080428

Title: Smad4-dependent TGF-beta signaling suppresses RON receptor tyrosine kinase-dependent motility and invasion of pancreatic cancer cells.

Journal: The Journal of biological chemistry20080425

Title: N-->O-Acyl shift in Fmoc-based synthesis of phosphopeptides.

Journal: Organic & biomolecular chemistry20080421

Title: Requirement of adaptor protein GULP during stabilin-2-mediated cell corpse engulfment.

Journal: The Journal of biological chemistry20080418

Title: Evaluation of protein kinase activities of cell lysates using peptide microarrays based on surface plasmon resonance imaging.

Journal: Analytical biochemistry20080415

Title: Subcellular receptor redistribution and enhanced microspike formation by a Ret receptor preferentially recruiting Dok.

Journal: Neuroscience letters20080411

Title: Synthesis, characterization and Stat3 inhibitory properties of the prototypical platinum(IV) anticancer drug, [PtCl3(NO2)(NH3)2] (CPA-7).

Journal: Inorganic chemistry20080407

Title: Identification of new tyrosine phosphorylated proteins in rat brain mitochondria.

Journal: FEBS letters20080402

Title: Effects of carboxyamidotriazole on in vitro models of imatinib-resistant chronic myeloid leukemia.

Journal: Journal of cellular physiology20080401

Title: Prostatic-like acid phosphatase in human endometrial glands and its cyclic activity.

Journal: Journal of molecular histology20080401

Title: Insulin resistance induced by tumor necrosis factor-alpha in myocytes and brown adipocytes.

Journal: Journal of animal science20080401

Title: Morphoregulation by acetylcholinesterase in fibroblasts and astrocytes.

Journal: Journal of cellular physiology20080401

Title: Defining the specificity space of the human SRC homology 2 domain.

Journal: Molecular & cellular proteomics : MCP20080401

Title: Cysteine-rich protein 61 and connective tissue growth factor induce deadhesion and anoikis of retinal pericytes.

Journal: Endocrinology20080401

Title: Impaired intercellular adhesion and immature adherens junctions in merlin-deficient human primary schwannoma cells.

Journal: Glia20080401

Title: FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival.

Journal: Cancer research20080401

Title: FGF19 exhibits neuroprotective effects on adult mammalian photoreceptors in vitro.

Journal: Investigative ophthalmology & visual science20080401

Title: Genome-wide prediction of SH2 domain targets using structural information and the FoldX algorithm.

Journal: PLoS computational biology20080401

Title: Hyperphosphorylated cortactin in cancer cells plays an inhibitory role in cell motility.

Journal: Molecular cancer research : MCR20080401

Title: Tac-beta1 inhibits FAK activation and Src signaling.

Journal: Biochemical and biophysical research communications20080328

Title: Regulation of adaptor protein GIT1 in platelets, leading to the interaction between GIT1 and integrin alpha(IIb)beta3.

Journal: Biochemical and biophysical research communications20080328

Title: The highly repetitive region of the Helicobacter pylori CagY protein comprises tandem arrays of an alpha-helical repeat module.

Journal: Journal of molecular biology20080328

Title: Activity of lapatinib a novel HER2 and EGFR dual kinase inhibitor in human endometrial cancer cells.

Journal: British journal of cancer20080325

Title: The inhibitory receptor LILRB1 modulates the differentiation and regulatory potential of human dendritic cells.

Journal: Blood20080315

Title: Ezrin is a target for oncogenic Kit mutants in murine erythroleukemia.

Journal: Blood20080315

Title: Modulation of gold(III) porphyrin 1a-induced apoptosis by mitogen-activated protein kinase signaling pathways.

Journal: Biochemical pharmacology20080315

Title: Pyruvate kinase M2 is a phosphotyrosine-binding protein.

Journal: Nature20080313

Title: Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates.

Journal: The EMBO journal20080305

Title: Insulin signaling stimulates insulin transport by bovine aortic endothelial cells.

Journal: Diabetes20080301

Title: GM1-induced activation of phosphatidylinositol 3-kinase: involvement of Trk receptors.

Journal: Journal of neurochemistry20080301

Title: Activation of protein kinase Cepsilon stimulates DNA-repair via epidermal growth factor receptor nuclear accumulation.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology20080301

Title: Focal adhesion kinase as well as p130Cas and paxillin is crucially involved in the enhanced malignant properties under expression of ganglioside GD3 in melanoma cells.

Journal: Biochimica et biophysica acta20080301

Title: Mitochondrial H2O2 limits U937 cell survival to peroxynitrite by promoting ERK1/2 dephosphorylation.

Journal: Biochimica et biophysica acta20080301

Title: Initiation of human myoblast differentiation via dephosphorylation of Kir2.1 K+ channels at tyrosine 242.

Journal: Development (Cambridge, England)20080301

Title: Analysis of the cell adhesion molecule sticks-and-stones reveals multiple redundant functional domains, protein-interaction motifs and phosphorylated tyrosines that direct myoblast fusion in Drosophila melanogaster.

Journal: Genetics20080301

Title: Tandem immunoprecipitation of phosphotyrosine-mass spectrometry (TIPY-MS) indicates C19ORF19 becomes tyrosine-phosphorylated and associated with activated epidermal growth factor receptor.

Journal: Journal of proteome research20080301

Title: Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2.

Journal: Nature structural & molecular biology20080301

Title: SpvC is a Salmonella effector with phosphothreonine lyase activity on host mitogen-activated protein kinases.

Journal: Molecular microbiology20080301

Title: Immunohistochemical analysis of phosphotyrosine signal transducer and activator of transcription 3 and epidermal growth factor receptor autocrine signaling pathways in head and neck cancers and metastatic lymph nodes.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20080301

Title: When a domain is not a domain.

Journal: Nature structural & molecular biology20080301

Title: A label-free quantification method by MS/MS TIC compared to SILAC and spectral counting in a proteomics screen.

Journal: Proteomics20080301

Title: RNA interference screen identifies Abl kinase and PDGFR signaling in Chlamydia trachomatis entry.

Journal: PLoS pathogens20080301

Title: Chlamydial entry involves TARP binding of guanine nucleotide exchange factors.

Journal: PLoS pathogens20080301

Title: Genomic organization and control of the grb7 gene family.

Journal: Current genomics20080301

Title: Protein kinase assay on peptide-conjugated gold nanoparticles.

Journal: Biosensors & bioelectronics20080227

Title: An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on Dok1 and talin binding.

Journal: The Journal of biological chemistry20080227

Title: Mutations causing DOK7 congenital myasthenia ablate functional motifs in Dok-7.

Journal: The Journal of biological chemistry20080227

Title: A critical role for Lyn in acute myeloid leukemia.

Journal: Blood20080215

Title: Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts.

Journal: Blood20080215

Title: The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans.

Journal: Nature20080214

Title: The JIP1 scaffold protein regulates axonal development in cortical neurons.

Journal: Current biology : CB20080212

Title: Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene.

Journal: Molecular psychiatry20080201

Title: Constitutive nuclear import of latent and activated STAT5a by its coiled coil domain.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20080201

Title: Involvement of cortactin and phosphotyrosine proteins in cell-cell contact formation in cultured bovine corneal endothelial cells.

Journal: Histochemistry and cell biology20080201

Title: Suppression of FUT1/FUT4 expression by siRNA inhibits tumor growth.

Journal: Biochimica et biophysica acta20080201

Title: A photoswitchable ITAM peptidomimetic: synthesis and real time surface plasmon resonance (SPR) analysis of the effects of cis-trans isomerization on binding.

Journal: Bioorganic & medicinal chemistry20080201

Title: Membrane targeting by APPL1 and APPL2: dynamic scaffolds that oligomerize and bind phosphoinositides.

Journal: Traffic (Copenhagen, Denmark)20080201

Title: Memo is homologous to nonheme iron dioxygenases and binds an ErbB2-derived phosphopeptide in its vestigial active site.

Journal: The Journal of biological chemistry20080201

Title: Regulation of FynT function by dual domain docking on PAG/Cbp.

Journal: The Journal of biological chemistry20080201

Title: The microtubule-associated protein tau is phosphorylated by Syk.

Journal: Biochimica et biophysica acta20080201

Title: Breast tumor kinase BRK requires kinesin-2 subunit KAP3A in modulation of cell migration.

Journal: Cellular signalling20080201

Title: Ezrin is a specific and direct target of protein tyrosine phosphatase PRL-3.

Journal: Biochimica et biophysica acta20080201

Title: Topology of molecular machines of the endoplasmic reticulum: a compilation of proteomics and cytological data.

Journal: Histochemistry and cell biology20080201

Title: Overexpression of EPHA2 receptor destabilizes adherens junctions via a RhoA-dependent mechanism.

Journal: Journal of cell science20080201

Title: Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors.

Journal: European journal of immunology20080201

Title: Phosphorylation and nuclear translocation of STAT3 regulated by the Epstein-Barr virus latent membrane protein 1 in nasopharyngeal carcinoma.

Journal: International journal of molecular medicine20080201

Title: Extracellular acidic environments induce phosphorylation of ZAP-70 in Jurkat T cells.

Journal: Immunology letters20080129

Title: Regulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) by Src involves tyrosine phosphorylation of PDK1 and Src homology 2 domain binding.

Journal: The Journal of biological chemistry20080118

Title: Minimal role for STAT1 in interleukin-6 signaling and actions in the murine brain.

Journal: Glia20080115

Title: A highly efficient route to enantiomerically pure l-N-Bz-Pmp(t-Bu)2-OH and incorporation into a peptide-based protein tyrosine phosphatase inhibitor.

Journal: Bioorganic & medicinal chemistry letters20080115

Title: Siah proteins induce the epidermal growth factor-dependent degradation of phospholipase Cepsilon.

Journal: The Journal of biological chemistry20080111

Title: Structure of the human protein kinase MPSK1 reveals an atypical activation loop architecture.

Journal: Structure (London, England : 1993)20080108

Title: Phosphorylation, desensitization and internalization of human alpha1B-adrenoceptors induced by insulin-like growth factor-I.

Journal: European journal of pharmacology20080106

Title: Skin testing correlates negatively with high-activity ACP1 *B/*C genotype.

Journal: International archives of allergy and immunology20080101

Title: Phorbol ester and hydrogen peroxide synergistically induce the interaction of diacylglycerol kinase gamma with the Src homology 2 and C1 domains of beta2-chimaerin.

Journal: The Biochemical journal20080101

Title: An enhanced association of RACK1 with Abl in cells transfected with oncogenic ras.

Journal: The international journal of biochemistry & cell biology20080101

Title: Inhibition of tyrosine kinase activity prevents the adhesive and cohesive properties of platelets and the expression of procoagulant activity in response to collagen.

Journal: Thrombosis research20080101

Title: Src family kinases: regulation of their activities, levels and identification of new pathways.

Journal: Biochimica et biophysica acta20080101

Title: The impact of delay in cryo-fixation on biomarkers of Src tyrosine kinase activity in human breast and bladder cancers.

Journal: Cancer chemotherapy and pharmacology20080101

Title: The PTB domain of tensin: NMR solution structure and phosphoinositides binding studies.

Journal: Biopolymers20080101

Title: A2 isoform of mammalian translation factor eEF1A displays increased tyrosine phosphorylation and ability to interact with different signalling molecules.

Journal: The international journal of biochemistry & cell biology20080101

Title: Motif decomposition of the phosphotyrosine proteome reveals a new N-terminal binding motif for SHIP2.

Journal: Molecular & cellular proteomics : MCP20080101

Title: Increase of doxorubicin-induced apoptosis after knock-down of gonadotropin-releasing hormone receptor expression in human endometrial, ovarian and breast cancer cells.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology20080101

Title: Molecular mechanisms of the antiproliferative activity of somatostatin receptors (SSTRs) in neuroendocrine tumors.

Journal: Frontiers in bioscience : a journal and virtual library20080101

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

Journal: Journal of proteome research20080101

Title: Structural basis for the binding of high affinity phosphopeptides to Stat3.

Journal: Biopolymers20080101

Title: Mass spectrometric detection of tyrosine sulfation in human pancreatic trypsinogens, but not in tumor-associated trypsinogen.

Journal: The FEBS journal20080101

Title: Molecular events involved in the increased expression of matrix metalloproteinase-9 by T lymphocytes of mammary tumor-bearing mice.

Journal: International journal of molecular medicine20080101

Title: Multiple paxillin binding sites regulate FAK function.

Journal: Journal of molecular signaling20080101

Title: SCOWLP classification: structural comparison and analysis of protein binding regions.

Journal: BMC bioinformatics20080101

Title: CD47 associates with alpha 5 integrin and regulates responses of human articular chondrocytes to mechanical stimulation in an in vitro model.

Journal: Arthritis research & therapy20080101

Title: Host-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transduction.

Journal: BMC systems biology20080101

Title: Drosophila cbl is essential for control of cell death and cell differentiation during eye development.

Journal: PloS one20080101

Title: PI-3K/Akt pathway-dependent cyclin D1 expression is responsible for arsenite-induced human keratinocyte transformation.

Journal: Environmental health perspectives20080101

Title: Cytosolic extract induces Tir translocation and pedestals in EPEC-infected red blood cells.

Journal: PLoS pathogens20080101

Title: Serotonin (5-HT) transport in human platelets is modulated by Src-catalysed Tyr-phosphorylation of the plasma membrane transporter SERT.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20080101

Title: Taurolithocholic acid-3 sulfate impairs insulin signaling in cultured rat hepatocytes and perfused rat liver.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20080101

Title: A novel ZAP-70 dependent FRET based biosensor reveals kinase activity at both the immunological synapse and the antisynapse.

Journal: PloS one20080101

Title: Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting.

Journal: PLoS medicine20080101

Title: Transcription-dependent epidermal growth factor receptor activation by hepatocyte growth factor.

Journal: Molecular cancer research : MCR20080101

Title: Redundancy and compensation in axon guidance: genetic analysis of the Drosophila Ptp10D/Ptp4E receptor tyrosine phosphatase subfamily.

Journal: Neural development20080101

Title: Protein tyrosine phosphatase-1B (PTP1B) helps regulate EGF-induced stimulation of S-phase entry in human corneal endothelial cells.

Journal: Molecular vision20080101

Title: Prolactin receptor signaling is essential for perinatal brown adipocyte function: a role for insulin-like growth factor-2.

Journal: PloS one20080101

Title: Differential effects of age on circulating and splenic leukocyte populations in C57BL/6 and BALB/c male mice.

Journal: Immunity & ageing : I & A20080101

Title: HLA-DR alpha 2 mediates negative signalling via binding to Tirc7 leading to anti-inflammatory and apoptotic effects in lymphocytes in vitro and in vivo.

Journal: PloS one20080101

Title: Prevention of hypovolemic circulatory collapse by IL-6 activated Stat3.

Journal: PloS one20080101

Title: The differentiation/retrodifferentiation program of human U937 leukemia cells is accompanied by changes of VCP/p97.

Journal: BMC cell biology20080101

Title: Proteomic analysis of the secretome of Leishmania donovani.

Journal: Genome biology20080101

Title: A cross-talk between TrkB and Ret tyrosine kinases receptors mediates neuroblastoma cells differentiation.

Journal: PloS one20080101

Title: Dramatic inhibition of osteoclast sealing ring formation and bone resorption in vitro by a WASP-peptide containing pTyr294 amino acid.

Journal: Journal of molecular signaling20080101

Title: The Gammaherpesvirus m2 protein manipulates the Fyn/Vav pathway through a multidocking mechanism of assembly.

Journal: PloS one20080101

Title: Protein tyrosine phosphatases: new markers and targets in oncology?

Journal: Current oncology (Toronto, Ont.)20080101

Title: S100A7-downregulation inhibits epidermal growth factor-induced signaling in breast cancer cells and blocks osteoclast formation.

Journal: PloS one20080101

Title: Topological analysis of MAPK cascade for kinetic ErbB signaling.

Journal: PloS one20080101

Title: The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of Src.

Journal: PloS one20080101

Title: Charge environments around phosphorylation sites in proteins.

Journal: BMC structural biology20080101

Title: Quantitative multicolor compositional imaging resolves molecular domains in cell-matrix adhesions.

Journal: PloS one20080101

Title: Characterization and site-directed mutagenesis of Wzb, an O-phosphatase from Lactobacillus rhamnosus.

Journal: BMC biochemistry20080101

Title: Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cgamma at the centrosome.

Journal: Molecular cancer20080101

Title: Erwin Schroedinger, Francis Crick and epigenetic stability.

Journal: Biology direct20080101

Title: The IBR5 phosphatase promotes Arabidopsis auxin responses through a novel mechanism distinct from TIR1-mediated repressor degradation.

Journal: BMC plant biology20080101

Title: A systems biology approach to analyse amplification in the JAK2-STAT5 signalling pathway.

Journal: BMC systems biology20080101

Title: Calculation of absolute protein-ligand binding constants with the molecular dynamics free energy perturbation method.

Journal: Methods in molecular biology (Clifton, N.J.)20080101

Title: Large-scale phosphorylation mapping reveals the extent of tyrosine phosphorylation in Arabidopsis.

Journal: Molecular systems biology20080101

Title: The clathrin-binding motif and the J-domain of Drosophila Auxilin are essential for facilitating Notch ligand endocytosis.

Journal: BMC developmental biology20080101

Title: Mammalian liver cytochrome c is tyrosine-48 phosphorylated in vivo, inhibiting mitochondrial respiration.

Journal: Biochimica et biophysica acta20080101

Title: CD45RB is a novel molecular therapeutic target to inhibit Abeta peptide-induced microglial MAPK activation.

Journal: PloS one20080101

Title: Reduced paxillin expression contributes to the antimetastatic effect of 4-hydroxycoumarin on B16-F10 melanoma cells.

Journal: Cancer cell international20080101

Title: Modulatory role of phospholipase D in the activation of signal transducer and activator of transcription (STAT)-3 by thyroid oncogenic kinase RET/PTC.

Journal: BMC cancer20080101

Title: Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated database of phosphorylation sites.

Journal: BMC bioinformatics20080101

Title: Modulation of erythrocyte deformability by PKC activity.

Journal: Clinical hemorheology and microcirculation20080101

Title: SOCS3 inhibiting migration of A549 cells correlates with PYK2 signaling in vitro.

Journal: BMC cancer20080101

Title: Altered splicing of CEACAM1 in breast cancer: identification of regulatory sequences that control splicing of CEACAM1 into long or short cytoplasmic domain isoforms.

Journal: Molecular cancer20080101

Title: Functional implications of plasma membrane condensation for T cell activation.

Journal: PloS one20080101

Title: Expression of the epidermal growth factor receptor (EGFR) and the phosphorylated EGFR in invasive breast carcinomas.

Journal: Breast cancer research : BCR20080101

Title: Formin 1-isoform IV deficient cells exhibit defects in cell spreading and focal adhesion formation.

Journal: PloS one20080101

Title: Important genetic checkpoints for insulin resistance in salt-sensitive (S) Dahl rats.

Journal: Cardiovascular diabetology20080101

Title: Role of X11 and ubiquilin as in vivo regulators of the amyloid precursor protein in Drosophila.

Journal: PloS one20080101

Title: Reelin induces a radial glial phenotype in human neural progenitor cells by activation of Notch-1.

Journal: BMC developmental biology20080101

Title: Targeted disruption of the PME-1 gene causes loss of demethylated PP2A and perinatal lethality in mice.

Journal: PloS one20080101

Title: STAT3 activation in pressure-overloaded feline myocardium: role for integrins and the tyrosine kinase BMX.

Journal: International journal of biological sciences20080101

Title: Susceptibility to glaucoma: differential comparison of the astrocyte transcriptome from glaucomatous African American and Caucasian American donors.

Journal: Genome biology20080101

Title: Immunity related genes in dipterans share common enrichment of AT-rich motifs in their 5' regulatory regions that are potentially involved in nucleosome formation.

Journal: BMC genomics20080101

Title: PPARgamma and Apoptosis in Cancer.

Journal: PPAR research20080101

Title: Implications of tyrosine phosphoproteomics in cervical carcinogenesis.

Journal: Journal of carcinogenesis20080101

Title: Expression of clottable protein of tiger shrimp (Penaeus monodon) in gonads and its possible role as nutrient source for the embryo.

Journal: Developmental and comparative immunology20080101

Title: The central proline rich region of POB1/REPS2 plays a regulatory role in epidermal growth factor receptor endocytosis by binding to 14-3-3 and SH3 domain-containing proteins.

Journal: BMC biochemistry20080101

Title: The function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters.

Journal: BMC neuroscience20080101

Title: Skeletal muscle munc18c and syntaxin 4 in human obesity.

Journal: Nutrition & metabolism20080101

Title: The neurotransmitter dopamine modulates vascular permeability in the endothelium.

Journal: Journal of molecular signaling20080101

Title: Dynamic expression of Dab2 in the mouse embryonic central nervous system.

Journal: BMC developmental biology20080101

Title: Germline EPHB2 receptor variants in familial colorectal cancer.

Journal: PloS one20080101

Title: Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice.

Journal: PloS one20080101

Title: A RasGAP SH3 peptide aptamer inhibits RasGAP-Aurora interaction and induces caspase-independent tumor cell death.

Journal: PloS one20080101

Title: HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells.

Journal: PloS one20080101

Title: Differential expression of Cathepsin S and X in the spinal cord of a rat neuropathic pain model.

Journal: BMC neuroscience20080101

Title: Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3.

Journal: Breast cancer research : BCR20080101

Title: Tyrosine phosphorylation of the UDP-glucose dehydrogenase of Escherichia coli is at the crossroads of colanic acid synthesis and polymyxin resistance.

Journal: PloS one20080101

Title: Overexpression of partner of numb induces asymmetric distribution of the PI4P 5-Kinase Skittles in mitotic sensory organ precursor cells in Drosophila.

Journal: PloS one20080101

Title: The genetics of feto-placental development: a study of acid phosphatase locus 1 and adenosine deaminase polymorphisms in a consecutive series of newborn infants.

Journal: Reproductive biology and endocrinology : RB&E20080101

Title: Phosphorylation sites on Tyr28 and the C-terminus of Rad9 are required for inhibition of premature chromosomal condensation across the entire S phase.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20080101

Title: Selective recognition of a tetra-amino-acid motif containing phosphorylated tyrosine residue by ribonucleopeptide.

Journal: Nucleic acids symposium series (2004)20080101

Title: Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK.

Journal: Molecular cancer20080101

Title: The protein-phosphatome of the human malaria parasite Plasmodium falciparum.

Journal: BMC genomics20080101

Title: Phosphorylation of p130Cas initiates Rac activation and membrane ruffling.

Journal: BMC cell biology20080101

Title: Magic-factor 1, a partial agonist of Met, induces muscle hypertrophy by protecting myogenic progenitors from apoptosis.

Journal: PloS one20080101

Title: Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines.

Journal: Journal of translational medicine20080101

Title: P38 MAP kinase signaling is required for the conversion of CD4+CD25- T cells into iTreg.

Journal: PloS one20080101

Title: The conservation pattern of short linear motifs is highly correlated with the function of interacting protein domains.

Journal: BMC genomics20080101

Title: Non-opsonic phagocytosis of Legionella pneumophila by macrophages is mediated by phosphatidylinositol 3-kinase.

Journal: PloS one20080101

Title: Short Linear Motifs recognized by SH2, SH3 and Ser/Thr Kinase domains are conserved in disordered protein regions.

Journal: BMC genomics20080101

Title: The cell signaling adaptor protein EPS-8 is essential for C. elegans epidermal elongation and interacts with the ankyrin repeat protein VAB-19.

Journal: PloS one20080101

Title: Quantifying information transfer by protein domains: analysis of the Fyn SH2 domain structure.

Journal: BMC structural biology20080101

Title: Odin (ANKS1A) is a Src family kinase target in colorectal cancer cells.

Journal: Cell communication and signaling : CCS20080101

Title: Varicose: a MAGUK required for the maturation and function of Drosophila septate junctions.

Journal: BMC developmental biology20080101

Title: A phosphotyrosine-imprinted polymer receptor for the recognition of tyrosine phosphorylated peptides.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20080101

Title: beta1-integrin mediates myelin-associated glycoprotein signaling in neuronal growth cones.

Journal: Molecular brain20080101

Title: Fak56 functions downstream of integrin alphaPS3betanu and suppresses MAPK activation in neuromuscular junction growth.

Journal: Neural development20080101

Title: Signal transduction of fertilization in frog eggs and anti-apoptotic mechanism in human cancer cells: common and specific functions of membrane microdomains.

Journal: The open biochemistry journal20080101

Title: Gamma-secretase inhibition combined with platinum compounds enhances cell death in a large subset of colorectal cancer cells.

Journal: Cell communication and signaling : CCS20080101

Title: Significance of the entire C-terminus in biological activities mediated by the RON receptor tyrosine kinase and its oncogenic variant RON160.

Journal: Journal of experimental & clinical cancer research : CR20080101

Title: Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors.

Journal: PloS one20080101

Title: Dystroglycan, Tks5 and Src mediated assembly of podosomes in myoblasts.

Journal: PloS one20080101

Title: The UPS in diabetes and obesity.

Journal: BMC biochemistry20080101

Title: The marine-derived oligosaccharide sulfate (MdOS), a novel multiple tyrosine kinase inhibitor, combats tumor angiogenesis both in vitro and in vivo.

Journal: PloS one20080101

Title: Comprehensive dissection of PDGF-PDGFR signaling pathways in PDGFR genetically defined cells.

Journal: PloS one20080101

Title: Crystal structures of the FAK kinase in complex with TAE226 and related bis-anilino pyrimidine inhibitors reveal a helical DFG conformation.

Journal: PloS one20080101

Title: Differential roles of the PKC novel isoforms, PKCdelta and PKCepsilon, in mouse and human platelets.

Journal: PloS one20080101

Title: Induction of galectin-1 expression by HTLV-I Tax and its impact on HTLV-I infectivity.

Journal: Retrovirology20080101

Title: Cell surface sialylation and fucosylation are regulated by L1 via phospholipase Cgamma and cooperate to modulate neurite outgrowth, cell survival and migration.

Journal: PloS one20080101

Title: IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis.

Journal: PloS one20080101

Title: Membrane androgen receptor activation triggers down-regulation of PI-3K/Akt/NF-kappaB activity and induces apoptotic responses via Bad, FasL and caspase-3 in DU145 prostate cancer cells.

Journal: Molecular cancer20080101

Title: Abelson tyrosine kinase links PDGFbeta receptor activation to cytoskeletal regulation of NMDA receptors in CA1 hippocampal neurons.

Journal: Molecular brain20080101

Title: Modulation of Src activity by low molecular weight protein tyrosine phosphatase during osteoblast differentiation.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20080101

Title: An incoherent magnetic field inhibited EGF receptor clustering and phosphorylation induced by a 50-Hz magnetic field in cultured FL cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20080101

Title: Pleiotropic effects in Eya3 knockout mice.

Journal: BMC developmental biology20080101

Title: Phosphorylation regulates SIRT1 function.

Journal: PloS one20080101

Title: Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.

Journal: Breast cancer research : BCR20080101

Title: Synergism of EGFR and c-Met pathways, cross-talk and inhibition, in non-small cell lung cancer.

Journal: Journal of carcinogenesis20080101

Title: [Functioning of tyrosine protein kinases and phosphatases in gastric mucosa cells under conditions of oxidative and nitrosative stress in gastric lesions].

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 )20080101

Title: Pervanadate stabilizes desmosomes.

Journal: Cell adhesion & migration20080101

Title: In vitro effects of budesonide on eosinophil-basophil lineage commitment.

Journal: The open respiratory medicine journal20080101

Title: Antidiabetic Bis-Maltolato-OxoVanadium(IV): conversion of inactive trans- to bioactive cis-BMOV for possible binding to target PTP-1B.

Journal: Drug design, development and therapy20080101

Title: Development of a HTRF kinase assay for determination of Syk activity.

Journal: Current chemical genomics20080101

Title: Podosomes and Invadopodia: Related structures with Common Protein Components that May Promote Breast Cancer Cellular Invasion.

Journal: Breast cancer : basic and clinical research20080101

Title: Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis.

Journal: Clinical and experimental gastroenterology20080101

Title: Molecular Mechanisms that Regulate Epidermal Growth Factor Receptor Inactivation.

Journal: Clinical medicine. Oncology20080101

Title: The effect of docetaxel (taxotere) on human gastric cancer cells exhibiting low-dose radiation hypersensitivity.

Journal: Clinical medicine. Oncology20080101

Title: 53BP2S, interacting with insulin receptor substrates, modulates insulin signaling.

Journal: The Journal of biological chemistry20071228

Title: Laminin-induced activation of Rac1 and JNKp46 is initiated by Src family kinases and mimics the effects of skeletal muscle contraction.

Journal: Biochemistry20071225

Title: Chemical DNA damage activates p21 WAF1/CIP1-dependent intra-S checkpoint.

Journal: FEBS letters20071222

Title: Structural insights into the enzymatic mechanism of the pathogenic MAPK phosphothreonine lyase.

Journal: Molecular cell20071214

Title: Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.

Journal: Cell20071214

Title: Endogenous phosphotyrosine signaling in zebrafish embryos.

Journal: Molecular & cellular proteomics : MCP20071201

Title: Signaling status of IgG B cell receptor (IgG BCR) is indicative for an activated state of circulating B cells in multiple myeloma.

Journal: Annals of hematology20071201

Title: Role of mitogen-activated protein kinase phosphatases (MKPs) in cancer.

Journal: Cancer metastasis reviews20071201

Title: Modulation of CD1d-restricted NKT cell responses by CD4.

Journal: Journal of leukocyte biology20071201

Title: FLT3 regulates beta-catenin tyrosine phosphorylation, nuclear localization, and transcriptional activity in acute myeloid leukemia cells.

Journal: Leukemia20071201

Title: hTRPC1-associated alpha-actinin, and not hTRPC1 itself, is tyrosine phosphorylated during human platelet activation.

Journal: Journal of thrombosis and haemostasis : JTH20071201

Title: Synaptic differentiation is defective in mice lacking acetylcholine receptor beta-subunit tyrosine phosphorylation.

Journal: Development (Cambridge, England)20071201

Title: 3D structure of Syk kinase determined by single-particle electron microscopy.

Journal: Biochimica et biophysica acta20071201

Title: [Specific recognition and detection of phosphorylated proteins using characteristics of metal ion].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan20071201

Title: Inhibition of tyrosine phosphorylation of vascular endothelial growth factor receptors in human umbilical vein endothelial cells: a potent anti-angiogenic lipid-rich extract from shark.

Journal: Journal of medicinal food20071201

Title: Phosphopeptide elution times in reversed-phase liquid chromatography.

Journal: Journal of chromatography. A20071116

Title: Oxygen isotopic substitution of peptidyl phosphates for modification-specific mass spectrometry.

Journal: Analytical chemistry20071115

Title: Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation.

Journal: Structure (London, England : 1993)20071113

Title: Activation of nonreceptor tyrosine kinase Bmx/Etk mediated by phosphoinositide 3-kinase, epidermal growth factor receptor, and ErbB3 in prostate cancer cells.

Journal: The Journal of biological chemistry20071109

Title: Platelet-derived growth factor-induced stabilization of cyclooxygenase 2 mRNA in rat smooth muscle cells requires the c-Src family of protein-tyrosine kinases.

Journal: The Journal of biological chemistry20071109

Title: Role of MAPK phosphatase-1 in sustained activation of JNK during ethanol-induced apoptosis in hepatocyte-like VL-17A cells.

Journal: The Journal of biological chemistry20071102

Title: Bisperoxovanadium, a phospho-tyrosine phosphatase inhibitor, reprograms myogenic cells to acquire a pluripotent, circulating phenotype.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20071101

Title: Nerve growth factor receptor TrkA signaling in breast cancer cells involves Ku70 to prevent apoptosis.

Journal: Molecular & cellular proteomics : MCP20071101

Title: Src family tyrosine kinases phosphorylate Flt3 on juxtamembrane tyrosines and interfere with receptor maturation in a kinase-dependent manner.

Journal: Annals of hematology20071101

Title: Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin.

Journal: Cellular signalling20071101

Title: Preformed STAT3 transducer complexes in human HepG2 cells and rat hepatocytes.

Journal: Cellular signalling20071101

Title: Proteomic identification of the cerebral cavernous malformation signaling complex.

Journal: Journal of proteome research20071101

Title: Proteomic approach for caudal trauma-induced acute phase proteins reveals that creatine kinase is a key acute phase protein in amphioxus humoral fluid.

Journal: Journal of proteome research20071101

Title: Capillary electrophoresis of phosphorylated amino acids with fluorescence detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20071101

Title: Mammalian diaphanous-related formin Dia1 controls the organization of E-cadherin-mediated cell-cell junctions.

Journal: Journal of cell science20071101

Title: HVEM signaling in monocytes is mediated by intracellular calcium mobilization.

Journal: Journal of immunology (Baltimore, Md. : 1950)20071101

Title: PTPsigma binds and dephosphorylates neurotrophin receptors and can suppress NGF-dependent neurite outgrowth from sensory neurons.

Journal: Biochimica et biophysica acta20071101

Title: Progressive loss of epidermal growth factor receptor in a subpopulation of breast cancers: implications in target-directed therapeutics.

Journal: Molecular cancer therapeutics20071101

Title: Inhibition of estradiol receptor/Src association and cell growth by an estradiol receptor alpha tyrosine-phosphorylated peptide.

Journal: Molecular cancer research : MCR20071101

Title: Synergistic effect of D-glucose and epidermal growth factor display on dynamic behaviors of human epithelial cells.

Journal: Journal of bioscience and bioengineering20071101

Title: Tyrosine phosphorylation-dependence of caveolae-mediated endocytosis.

Journal: Journal of cellular and molecular medicine20071101

Title: Phosphoproteomics.

Journal: Current protocols in protein science20071101

Title: The control of phosphatidylinositol 3,4-bisphosphate concentrations by activation of the Src homology 2 domain containing inositol polyphosphate 5-phosphatase 2, SHIP2.

Journal: The Biochemical journal20071015

Title: Regulation of arginine methylation in endothelial cells: role in premature senescence and apoptosis.

Journal: Cell cycle (Georgetown, Tex.)20071015

Title: alpha-Tocopherol modifies tyrosine phosphorylation and capacitation-like state of cryopreserved porcine sperm.

Journal: Theriogenology20071015

Title: Liquid chromatographic analysis of phosphoamino acids at femtomole level using chemical derivatization with N-hydroxysuccinimidyl fluorescein-O-acetate.

Journal: Analytica chimica acta20071003

Title: NPM/ALK binds and phosphorylates the RNA/DNA-binding protein PSF in anaplastic large-cell lymphoma.

Journal: Blood20071001

Title: Expression, generation, and purification of unphosphorylated and phospho-Ser-380/Thr-382/Thr-383 form of recombinant PTEN phosphatase.

Journal: Protein expression and purification20071001

Title: Transforming growth factor-beta1 effects on endothelial monolayer permeability involve focal adhesion kinase/Src.

Journal: American journal of respiratory cell and molecular biology20071001

Title: Suberoylanilide hydroxamic acid (SAHA; vorinostat) suppresses translation of cyclin D1 in mantle cell lymphoma cells.

Journal: Blood20071001

Title: Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling.

Journal: Blood20071001

Title: PECAM-1 engagement counteracts ICAM-1-induced signaling in brain vascular endothelial cells.

Journal: Journal of neurochemistry20071001

Title: Expression of Hsp60 and Grp78 in the human endometrium and oviduct, and their effect on sperm functions.

Journal: Human reproduction (Oxford, England)20071001

Title: Src regulates phorbol 12-myristate 13-acetate-activated PKC-induced migration via Cas/Crk/Rac1 signaling pathway in glioblastoma cells.

Journal: International journal of molecular medicine20071001

Title: BDCA2/Fc epsilon RI gamma complex signals through a novel BCR-like pathway in human plasmacytoid dendritic cells.

Journal: PLoS biology20071001

Title: Natural phosphorylation of CD5 in chronic lymphocytic leukemia B cells and analysis of CD5-regulated genes in a B cell line suggest a role for CD5 in malignant phenotype.

Journal: Journal of immunology (Baltimore, Md. : 1950)20071001

Title: Fyn regulates the duration of TCR engagement needed for commitment to effector function.

Journal: Journal of immunology (Baltimore, Md. : 1950)20071001

Title: Role of tyrosine phosphorylation in U46619-induced vasoconstriction of pulmonary vasculature and its modulation by genistein, daidzein, and equol.

Journal: Journal of cardiovascular pharmacology20071001

Title: A remodelled protease that cleaves phosphotyrosine substrates.

Journal: Journal of the American Chemical Society20070926

Title: The activation and inhibition of cyclin-dependent kinase-5 by phosphorylation.

Journal: Biochemistry20070925

Title: Stat5 activation inhibits prolactin-induced AP-1 activity: distinct prolactin-initiated signals in tumorigenesis dependent on cell context.

Journal: Oncogene20070920

Title: Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding site.

Journal: Journal of medicinal chemistry20070920

Title: Polymers with tunable toxicity: a reference scale for cytotoxicity testing of biomaterial surfaces.

Journal: Journal of biomedical materials research. Part A20070915

Title: The low-molecular-weight phosphotyrosine phosphatase is a negative regulator of FcgammaRIIA-mediated cell activation.

Journal: Blood20070915

Title: Structural basis for UBA-mediated dimerization of c-Cbl ubiquitin ligase.

Journal: The Journal of biological chemistry20070914

Title: Using measurements of anchoring energies of liquid crystals on surfaces to quantify proteins captured by immobilized ligands.

Journal: Journal of the American Chemical Society20070912

Title: Role of c-Abl in directing metabolic versus mitogenic effects in insulin receptor signaling.

Journal: The Journal of biological chemistry20070907

Title: A double tyrosine phosphorylation of P68 RNA helicase confers resistance to TRAIL-induced apoptosis.

Journal: Oncogene20070906

Title: Antiaggregant effects of Arbutus unedo extracts in human platelets.

Journal: Journal of ethnopharmacology20070905

Title: L-NAME reverses quinolinic acid-induced toxicity in rat corticostriatal slices: Involvement of src family kinases.

Journal: Journal of neuroscience research20070901

Title: Protein kinase Cepsilon may act as EGF-inducible scaffold protein for phospholipase Cgamma1.

Journal: Cellular signalling20070901

Title: Analysis of chaperone proteins associated with human spermatozoa during capacitation.

Journal: Molecular human reproduction20070901

Title: High tidal volume mechanical ventilation with hyperoxia alters alveolar type II cell adhesion.

Journal: American journal of physiology. Lung cellular and molecular physiology20070901

Title: Regulation of airway goblet cell mucin secretion by tyrosine phosphorylation signaling pathways.

Journal: American journal of physiology. Lung cellular and molecular physiology20070901

Title: Kinetics and mechanism of protein tyrosine phosphatase 1B inactivation by acrolein.

Journal: Chemical research in toxicology20070901

Title: Molecular mechanisms underlying the synergistic induction of CXCL10 by LPS and IFN-gamma in human neutrophils.

Journal: European journal of immunology20070901

Title: Label-free electrical sensing of small-molecule inhibition on tyrosine phosphorylation.

Journal: Analytical chemistry20070901

Title: Hypophosphorylated TCR/CD3zeta signals through a Grb2-SOS1-Ras pathway in Lck knockdown cells.

Journal: European journal of immunology20070901

Title: The radioprotector O-phospho-tyrosine stimulates DNA-repair via epidermal growth factor receptor- and DNA-dependent kinase phosphorylation.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology20070901

Title: Higher-energy C-trap dissociation for peptide modification analysis.

Journal: Nature methods20070901

Title: Signal transduction mechanisms of CD137 ligand in human monocytes.

Journal: Cellular signalling20070901

Title: Apoptotic killing of HIV-1-infected macrophages is subverted by the viral envelope glycoprotein.

Journal: PLoS pathogens20070901

Title: Connective tissue progenitor cell growth characteristics on textured substrates.

Journal: International journal of nanomedicine20070901

Title: PTPL1/FAP-1 negatively regulates TRIP6 function in lysophosphatidic acid-induced cell migration.

Journal: The Journal of biological chemistry20070817

Title: The commonality of protein interaction networks determined in neurodegenerative disorders (NDDs).

Journal: Bioinformatics (Oxford, England)20070815

Title: An ultrasensitive high-throughput electrochemiluminescence immunoassay for the Cdc42-associated protein tyrosine kinase ACK1.

Journal: Analytical biochemistry20070815

Title: Mapping ErbB receptors on breast cancer cell membranes during signal transduction.

Journal: Journal of cell science20070815

Title: ZRP-1 controls Rho GTPase-mediated actin reorganization by localizing at cell-matrix and cell-cell adhesions.

Journal: Journal of cell science20070815

Title: Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion.

Journal: British journal of cancer20070806

Title: Tyk2 mediates effects of urokinase on human vascular smooth muscle cell growth.

Journal: Biochemical and biophysical research communications20070803

Title: Microtubules regulate PI-3K activity and recruitment to the phagocytic cup during Fcgamma receptor-mediated phagocytosis in nonelicited macrophages.

Journal: Journal of leukocyte biology20070801

Title: Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life.

Journal: Molecular and cellular biology20070801

Title: Protein tyrosine dephosphorylation during copper-induced cell death in rice roots.

Journal: Chemosphere20070801

Title: Systemic analysis of tyrosine phosphorylated proteins in angiopoietin-1 induced signaling pathway of endothelial cells.

Journal: Journal of proteome research20070801

Title: Sensitivity of breast cancer cells to erlotinib depends on cyclin-dependent kinase 2 activity.

Journal: Molecular cancer therapeutics20070801

Title: c-Src/histone deacetylase 3 interaction is crucial for hepatocyte growth factor dependent decrease of CXCR4 expression in highly invasive breast tumor cells.

Journal: Molecular cancer research : MCR20070801

Title: Acute pharmacodynamic and antivascular effects of the vascular endothelial growth factor signaling inhibitor AZD2171 in Calu-6 human lung tumor xenografts.

Journal: Molecular cancer therapeutics20070801

Title: Therapeutic targeting of nuclear receptor corepressor misfolding in acute promyelocytic leukemia cells with genistein.

Journal: Molecular cancer therapeutics20070801

Title: A logical model provides insights into T cell receptor signaling.

Journal: PLoS computational biology20070801

Title: The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications.

Journal: Current genomics20070801

Title: Synthesis and evaluation of tripodal peptide analogues for cellular delivery of phosphopeptides.

Journal: Journal of medicinal chemistry20070726

Title: A genetically encoded metabolically stable analogue of phosphotyrosine in Escherichia coli.

Journal: ACS chemical biology20070720

Title: A lock on phosphotyrosine signaling.

Journal: ACS chemical biology20070720

Title: Inhibition of epidermal growth factor receptor signalling reduces hypercalcaemia induced by human lung squamous-cell carcinoma in athymic mice.

Journal: British journal of cancer20070716

Title: Palladin interacts with SH3 domains of SPIN90 and Src and is required for Src-induced cytoskeletal remodeling.

Journal: Experimental cell research20070715

Title: Cholesterol depletion alters detergent-specific solubility profiles of selected tight junction proteins and the phosphorylation of occludin.

Journal: Experimental cell research20070715

Title: RACK1 regulates Src activity and modulates paxillin dynamics during cell migration.

Journal: Experimental cell research20070715

Title: Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1.

Journal: The EMBO journal20070711

Title: alpha-Tomatine, the major saponin in tomato, induces programmed cell death mediated by reactive oxygen species in the fungal pathogen Fusarium oxysporum.

Journal: FEBS letters20070710

Title: Full CD3/TCR activation through cholesterol-depleted lipid rafts.

Journal: Cellular signalling20070701

Title: A transmembrane osteoclastic protein-tyrosine phosphatase regulates osteoclast activity in part by promoting osteoclast survival through c-Src-dependent activation of NFkappaB and JNK2.

Journal: Archives of biochemistry and biophysics20070701

Title: Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinase.

Journal: Molecular and cellular biology20070701

Title: Ganglioside GM(3) is stably associated to tyrosine-phosphorylated ErbB2/EGFR receptor complexes and EGFR monomers, but not to ErbB2.

Journal: Biochimica et biophysica acta20070701

Title: Quantitation of multisite EGF receptor phosphorylation using mass spectrometry and a novel normalization approach.

Journal: Journal of proteome research20070701

Title: Redox-dependent and ligand-independent trans-activation of insulin receptor by globular adiponectin.

Journal: Hepatology (Baltimore, Md.)20070701

Title: Defining SH2 domain and PTP specificity by screening combinatorial peptide libraries.

Journal: Methods (San Diego, Calif.)20070701

Title: Analyzing protein tyrosine phosphatases by phosphotyrosine analog integration.

Journal: Methods (San Diego, Calif.)20070701

Title: Generation of inhibitor-sensitive protein tyrosine phosphatases via active-site mutations.

Journal: Methods (San Diego, Calif.)20070701

Title: L-type calcium channels mediate acetylcholine receptor aggregation on cultured muscle.

Journal: Developmental neurobiology20070701

Title: A role for acetylcholine receptors in their own aggregation on muscle cells.

Journal: Developmental neurobiology20070701

Title: Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells.

Journal: Proteomics20070701

Title: Sensitivity analysis of intracellular signaling pathway kinetics predicts targets for stem cell fate control.

Journal: PLoS computational biology20070701

Title: Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity.

Journal: Molecular cancer therapeutics20070701

Title: Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli.

Journal: PLoS pathogens20070701

Title: Study on the mechanisms of an extract of Salvia miltiorrhiza on the regulation of permeability of endothelial cells exposed to tumour necrosis factor-alpha.

Journal: The Journal of pharmacy and pharmacology20070701

Title: Relaxin signalling in THP-1 cells uses a novel phosphotyrosine-dependent pathway.

Journal: Molecular and cellular endocrinology20070630

Title: Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro.

Journal: Biochemistry20070626

Title: High-throughput phosphotyrosine profiling using SH2 domains.

Journal: Molecular cell20070622

Title: Acquired resistance to erlotinib in A-431 epidermoid cancer cells requires down-regulation of MMAC1/PTEN and up-regulation of phosphorylated Akt.

Journal: Cancer research20070615

Title: Specific Grb2-mediated interactions regulate clathrin-dependent endocytosis of the cMet-tyrosine kinase.

Journal: The Journal of biological chemistry20070608

Title: Protein kinase Calpha mediates feedback inhibition of EGF receptor transactivation induced by Gq-coupled receptor agonists.

Journal: Cellular signalling20070601

Title: Identification of novel fragment compounds targeted against the pY pocket of v-Src SH2 by computational and NMR screening and thermodynamic evaluation.

Journal: Proteins20070601

Title: Mechanisms of tumour cell invasion and metastasis.

Journal: Journal of molecular medicine (Berlin, Germany)20070601

Title: The structure-activity relationship of the series of non-peptide small antagonists for p56lck SH2 domain.

Journal: Bioorganic & medicinal chemistry20070601

Title: An ectophosphatase activity in Candida parapsilosis influences the interaction of fungi with epithelial cells.

Journal: FEMS yeast research20070601

Title: Not so simple: the complexity of phosphotyrosine signaling at cadherin adhesive contacts.

Journal: Journal of molecular medicine (Berlin, Germany)20070601

Title: Localized activation of Src-family protein kinases in the mouse egg.

Journal: Developmental biology20070601

Title: Structural and energetic aspects of Grb2-SH2 domain-swapping.

Journal: Archives of biochemistry and biophysics20070601

Title: Structure of the PTB domain of tensin1 and a model for its recruitment to fibrillar adhesions.

Journal: Protein science : a publication of the Protein Society20070601

Title: TccP2-mediated subversion of actin dynamics by EPEC 2 - a distinct evolutionary lineage of enteropathogenic Escherichia coli.

Journal: Microbiology (Reading, England)20070601

Title: Cell surface receptors for signal transduction and ligand transport: a design principles study.

Journal: PLoS computational biology20070601

Title: Effects of PPAR-gamma knock-down and hyperglycemia on insulin signaling in vascular smooth muscle cells from hypertensive rats.

Journal: Journal of cardiovascular pharmacology20070601

Title: Is the c-Cbl proto-oncogene involved in chronic lymphocytic leukemia?

Journal: Annals of the New York Academy of Sciences20070601

Title: Cetuximab in the management of colorectal cancer.

Journal: Biologics : targets & therapy20070601

Title: A multiplexed protein kinase assay.

Journal: Chembiochem : a European journal of chemical biology20070525

Title: Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases.

Journal: Nature20070524

Title: A molecular dynamics study of WPD-loop flexibility in PTP1B.

Journal: Biochemical and biophysical research communications20070518

Title: TCRzetadim lymphocytes define populations of circulating effector cells that migrate to inflamed tissues.

Journal: Blood20070515

Title: A remote substrate docking mechanism for the tec family tyrosine kinases.

Journal: Biochemistry20070508

Title: Development of molecular probes for second-site screening and design of protein tyrosine phosphatase inhibitors.

Journal: Journal of medicinal chemistry20070503

Title: The role of ghrelin and some intracellular mechanisms in controlling the secretory activity of chicken ovarian cells.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology20070501

Title: Identification and distribution of a novel platelet-derived growth factor receptor beta variant: effect of retinoic acid and involvement in cell differentiation.

Journal: Endocrinology20070501

Title: Domains necessary for Galpha12 binding and stimulation of protein phosphatase-2A (PP2A): Is Galpha12 a novel regulatory subunit of PP2A?

Journal: Molecular pharmacology20070501

Title: Localization and regulation of plasma membrane Ca(2+)-ATPase in bovine spermatozoa.

Journal: European journal of cell biology20070501

Title: Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region.

Journal: European journal of immunology20070501

Title: Molecular mechanisms of the diabetogenic effects of arsenic: inhibition of insulin signaling by arsenite and methylarsonous acid.

Journal: Environmental health perspectives20070501

Title: CD99 activates T cells via a costimulatory function that promotes raft association of TCR complex and tyrosine phosphorylation of TCR zeta.

Journal: Experimental & molecular medicine20070430

Title: Hierarchical disabled-1 tyrosine phosphorylation in Src family kinase activation and neurite formation.

Journal: Journal of molecular biology20070427

Title: Structural studies of E. coli topoisomerase III-DNA complexes reveal a novel type IA topoisomerase-DNA conformational intermediate.

Journal: Journal of molecular biology20070420

Title: Examination of acylated 4-aminopiperidine-4-carboxylic acid residues in the phosphotyrosyl+1 position of Grb2 SH2 domain-binding tripeptides.

Journal: Journal of medicinal chemistry20070419

Title: Regulation of Arf6 and ACAP1 signaling by the PTB-domain-containing adaptor protein GULP.

Journal: Current biology : CB20070417

Title: Paxillin family members function as Csk-binding proteins that regulate Lyn activity in human and murine platelets.

Journal: The Biochemical journal20070415

Title: Imatinib increases the intracellular concentration of nilotinib, which may explain the observed synergy between these drugs.

Journal: Blood20070415

Title: The receptor tyrosine kinase EphB4 is overexpressed in ovarian cancer, provides survival signals and predicts poor outcome.

Journal: British journal of cancer20070410

Title: The role of presenilin and its interacting proteins in the biogenesis of Alzheimer's beta amyloid.

Journal: Neurochemical research20070401

Title: Association of protein kinase C-delta with the B cell antigen receptor complex.

Journal: Cellular signalling20070401

Title: Entamoeba histolytica: an ecto-phosphatase activity regulated by oxidation-reduction reactions.

Journal: Experimental parasitology20070401

Title: A proteomic approach to the investigation of early events involved in vascular smooth muscle cell activation.

Journal: Cell and tissue research20070401

Title: CCK causes PKD1 activation in pancreatic acini by signaling through PKC-delta and PKC-independent pathways.

Journal: Biochimica et biophysica acta20070401

Title: FGFR3 intracellular mutations induce tyrosine phosphorylation in the Golgi and defective glycosylation.

Journal: Biochimica et biophysica acta20070401

Title: Cdk5 is involved in BDNF-stimulated dendritic growth in hippocampal neurons.

Journal: PLoS biology20070401

Title: Regulation of B-lymphocyte activation by the PH domain adaptor protein Bam32/DAPP1.

Journal: Biochemical Society transactions20070401

Title: Phosphotyrosine/phosphoserine binary switches: a new paradigm for the regulation of PI3K signalling and growth factor pleiotropy?

Journal: Biochemical Society transactions20070401

Title: High expression of several tyrosine kinases and activation of the PI3K/AKT pathway in mediastinal large B cell lymphoma reveals further similarities to Hodgkin lymphoma.

Journal: Leukemia20070401

Title: Evaluation of enrichment techniques for mass spectrometry: identification of tyrosine phosphoproteins in cancer cells.

Journal: The Journal of molecular diagnostics : JMD20070401

Title: Dasatinib (BMS-354825) inhibits Stat5 signaling associated with apoptosis in chronic myelogenous leukemia cells.

Journal: Molecular cancer therapeutics20070401

Title: Structural basis for selective inhibition of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB.

Journal: Structure (London, England : 1993)20070401

Title: Asymmetric synthesis of the (S)-1,1-dioxido-isothiazolidin-3-one phosphotyrosine mimetic via reduction of a homochiral (R)-oxido-isothiazolidin-3-one.

Journal: Organic letters20070329

Title: Src family kinases mediate neutrophil adhesion to adherent platelets.

Journal: Blood20070315

Title: c-Src activates endonuclease-mediated mRNA decay.

Journal: Molecular cell20070309

Title: Cordycepin (3'-deoxyadenosine) inhibits human platelet aggregation in a cyclic AMP- and cyclic GMP-dependent manner.

Journal: European journal of pharmacology20070308

Title: ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells.

Journal: Blood20070301

Title: Beneficial effects of combining nilotinib and imatinib in preclinical models of BCR-ABL+ leukemias.

Journal: Blood20070301

Title: Acute impairment of insulin signalling by dexamethasone in primary cultured rat skeletal myocytes.

Journal: Molecular and cellular biochemistry20070301

Title: Cr(VI)-stimulated STAT3 tyrosine phosphorylation and nuclear translocation in human airway epithelial cells requires Lck.

Journal: The Biochemical journal20070301

Title: Acetaldehyde dissociates the PTP1B-E-cadherin-beta-catenin complex in Caco-2 cell monolayers by a phosphorylation-dependent mechanism.

Journal: The Biochemical journal20070301

Title: Suppression effect of seminal vesicle autoantigen on platelet-activating factor-induced mouse sperm capacitation.

Journal: Journal of cellular biochemistry20070301

Title: Enzyme-substrate interactions revealed by the crystal structures of the archaeal Sulfolobus PTP-fold phosphatase and its phosphopeptide complexes.

Journal: Proteins20070301

Title: Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells.

Journal: Molecular immunology20070301

Title: Two axes in platelet-derived growth factor signaling: tyrosine phosphorylation and reactive oxygen species.

Journal: Cellular and molecular life sciences : CMLS20070301

Title: Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD.

Journal: Leukemia20070301

Title: Semisynthesis of unnatural amino acid mutants of paxillin: protein probes for cell migration studies.

Journal: Protein science : a publication of the Protein Society20070301

Title: Phosphoproteomic analysis identifies the M0-91 cell line as a cellular model for the study of TEL-TRKC fusion-associated leukemia.

Journal: Leukemia20070301

Title: Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility.

Journal: Nature structural & molecular biology20070301

Title: MAPK phosphatases--regulating the immune response.

Journal: Nature reviews. Immunology20070301

Title: Exploring DNA topoisomerases as targets of novel therapeutic agents in the treatment of infectious diseases.

Journal: Infectious disorders drug targets20070301

Title: Src family kinase activity regulates adhesion, spreading and migration of pancreatic endocrine tumour cells.

Journal: Endocrine-related cancer20070301

Title: Gefitinib-sensitive EGFR lacking residues 746-750 exhibits hypophosphorylation at tyrosine residue 1045, hypoubiquitination, and impaired endocytosis.

Journal: DNA and cell biology20070301

Title: Immunological outcomes of exercise in older adults.

Journal: Clinical interventions in aging20070301

Title: Immunosupportive therapies in aging.

Journal: Clinical interventions in aging20070301

Title: Cell death and cytotoxic effects in YAC-1 lymphoma cells following exposure to various forms of mercury.

Journal: Toxicology20070227

Title: PMA activates Stat3 in the Jak/Stat pathway and induces SOCS5 in rat brain astrocytes.

Journal: Molecules and cells20070227

Title: Src signaling regulates completion of abscission in cytokinesis through ERK/MAPK activation at the midbody.

Journal: The Journal of biological chemistry20070223

Title: ALK activation induces Shc and FRS2 recruitment: Signaling and phenotypic outcomes in PC12 cells differentiation.

Journal: FEBS letters20070220

Title: Reverse interactomics: from peptides to proteins and to functions.

Journal: ACS chemical biology20070220

Title: The phosphothreonine lyase activity of a bacterial type III effector family.

Journal: Science (New York, N.Y.)20070216

Title: Direct on-membrane peptide mass fingerprinting with MALDI-MS of tyrosine-phosphorylated proteins detected by immunostaining.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20070215

Title: Gonadotropin-releasing hormone type II antagonists induce apoptotic cell death in human endometrial and ovarian cancer cells in vitro and in vivo.

Journal: Cancer research20070215

Title: The structure of the minimal relaxase domain of MobA at 2.1 A resolution.

Journal: Journal of molecular biology20070209

Title: Two tyrosine residues of Toll-like receptor 3 trigger different steps of NF-kappa B activation.

Journal: The Journal of biological chemistry20070209

Title: Homogeneous time-resolved fluorescence assays for the detection of activity and inhibition of phosphatase enzymes employing phosphorescently labeled peptide substrates.

Journal: Analytica chimica acta20070205

Title: How tyrosine 15 phosphorylation inhibits the activity of cyclin-dependent kinase 2-cyclin A.

Journal: The Journal of biological chemistry20070202

Title: Src-family tyrosine kinase fyn phosphorylates phosphatidylinositol 3-kinase enhancer-activating Akt, preventing its apoptotic cleavage and promoting cell survival.

Journal: Cell death and differentiation20070201

Title: BCL-2 expression is mainly regulated by JAK/STAT3 pathway in human CD34+ hematopoietic cells.

Journal: Cell death and differentiation20070201

Title: c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology20070201

Title: Trophoblast adhesion of the peri-implantation mouse blastocyst is regulated by integrin signaling that targets phospholipase C.

Journal: Developmental biology20070201

Title: Late signaling in the activated platelets upregulates tyrosine phosphatase SHP1 and impairs platelet adhesive functions: Regulation by calcium and Src kinase.

Journal: Biochimica et biophysica acta20070201

Title: Activation of human T lymphocytes via integrin signaling induced by RGD-disintegrins.

Journal: Biochimica et biophysica acta20070201

Title: Phosphorylation-dependent metal binding by alpha-synuclein peptide fragments.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry20070201

Title: Identification of the ligands of protein interaction domains through a functional approach.

Journal: Molecular & cellular proteomics : MCP20070201

Title: Apoptosis induced by crocidolite asbestos in human lung epithelial cells involves inactivation of Akt and MAPK pathways.

Journal: Apoptosis : an international journal on programmed cell death20070201

Title: Lysophosphatidic acid promoting corneal epithelial wound healing by transactivation of epidermal growth factor receptor.

Journal: Investigative ophthalmology & visual science20070201

Title: Proteomic analysis of tyrosine phosphorylations in vascular endothelial growth factor- and reactive oxygen species-mediated signaling pathway.

Journal: Journal of proteome research20070201

Title: Quantitative proteomic approaches for studying phosphotyrosine signaling.

Journal: Expert review of proteomics20070201

Title: Interaction between krit1 and malcavernin: implications for the pathogenesis of cerebral cavernous malformations.

Journal: Neurosurgery20070201

Title: Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function.

Journal: PLoS biology20070201

Title: Identification of a potential general acid/base in the reversible phosphoryl transfer reactions catalyzed by tyrosine recombinases: Flp H305.

Journal: Chemistry & biology20070201

Title: AP20187-mediated activation of a chimeric insulin receptor results in insulin-like actions in skeletal muscle and liver of diabetic mice.

Journal: Human gene therapy20070201

Title: Platelets possess functional TGF-beta receptors and Smad2 protein.

Journal: Platelets20070201

Title: PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration.

Journal: Current biology : CB20070123

Title: Utilization of achiral alkenyl amines for the preparation of high affinity Grb2 SH2 domain-binding macrocycles by ring-closing metathesis.

Journal: Organic & biomolecular chemistry20070121

Title: Candidate gene polymorphisms in the serotonergic pathway: influence on depression symptomatology in an elderly population.

Journal: Biological psychiatry20070115

Title: Redundancy in B cell developmental pathways: c-Cbl inactivation rescues early B cell development through a B cell linker protein-independent pathway.

Journal: Journal of immunology (Baltimore, Md. : 1950)20070115

Title: Identification of CXCL11 as a STAT3-dependent gene induced by IFN.

Journal: Journal of immunology (Baltimore, Md. : 1950)20070115

Title: The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export.

Journal: Genes & development20070115

Title: Proliferation and apoptosis in PhIP-induced rat mammary gland carcinomas with elevated phosphotyrosine-STAT5a.

Journal: FEBS letters20070109

Title: Halothane affects focal adhesion proteins in the A 549 cells.

Journal: Molecular and cellular biochemistry20070101

Title: UNC-51-like kinase regulation of fibroblast growth factor receptor substrate 2/3.

Journal: Cellular signalling20070101

Title: Focal adhesion signaling is required for myometrial ERK activation and contractile phenotype switch before labor.

Journal: Journal of cellular biochemistry20070101

Title: Role of protein phosphatase 2A in calcium-dependent chloride secretion by human colonic epithelial cells.

Journal: American journal of physiology. Cell physiology20070101

Title: Staurosporine induces tyrosine phosphorylation in Dictyostelium discoideum proteins.

Journal: Cell biochemistry and function20070101

Title: An intracellular multi-effector complex mediates somatostatin receptor 1 activation of phospho-tyrosine phosphatase eta.

Journal: Molecular endocrinology (Baltimore, Md.)20070101

Title: Crystal structure of human TMDP, a testis-specific dual specificity protein phosphatase: implications for substrate specificity.

Journal: Proteins20070101

Title: Involvement of Src kinases and PLCgamma2 in clot retraction.

Journal: Thrombosis research20070101

Title: Uteroglobin induces the development and cellular proliferation of the mouse early embryo.

Journal: Journal of experimental zoology. Part A, Ecological genetics and physiology20070101

Title: Focus on phosphohistidine.

Journal: Amino acids20070101

Title: Measurement of the formation of complexes in tyrosine kinase-mediated signal transduction.

Journal: Acta crystallographica. Section D, Biological crystallography20070101

Title: The use of biophysical methods increases success in obtaining liganded crystal structures.

Journal: Acta crystallographica. Section D, Biological crystallography20070101

Title: Enrichment of phosphotyrosine proteome of human platelets by immunoprecipitation.

Journal: Methods in molecular biology (Clifton, N.J.)20070101

Title: The effects of lidocaine and bupivacaine on protein expression of cleaved caspase 3 and tyrosine phosphorylation in the rat hippocampal slice.

Journal: Anesthesia and analgesia20070101

Title: Involvement of apolipoprotein E in excess fat accumulation and insulin resistance.

Journal: Diabetes20070101

Title: Effects of seminal plasma on cooling-induced capacitative changes in boar sperm.

Journal: Journal of andrology20070101

Title: Proteomic analysis of tyrosine phosphorylation during human liver transplantation.

Journal: Proteome science20070101

Title: Modeling HER2 effects on cell behavior from mass spectrometry phosphotyrosine data.

Journal: PLoS computational biology20070101

Title: Grb2-associated binder 1 polymorphism was associated with the risk of Helicobactor pylori infection and gastric atrophy.

Journal: International journal of medical sciences20070101

Title: AYUMS: an algorithm for completely automatic quantitation based on LC-MS/MS proteome data and its application to the analysis of signal transduction.

Journal: BMC bioinformatics20070101

Title: Sensitivity to pertuzumab (2C4) in ovarian cancer models: cross-talk with estrogen receptor signaling.

Journal: Molecular cancer therapeutics20070101

Title: Quantitating peptide-protein interactions.

Journal: Journal of proteome research20070101

Title: ArhGAP9, a novel MAP kinase docking protein, inhibits Erk and p38 activation through WW domain binding.

Journal: Journal of molecular signaling20070101

Title: Caspase-dependent proteolytic cleavage of STAT3alpha in ES cells, in mammary glands undergoing forced involution and in breast cancer cell lines.

Journal: BMC cancer20070101

Title: Cytokine responses of human lung cells (BEAS-2B) treated with micron-sized and nanoparticles of metal oxides compared to soil dusts.

Journal: Particle and fibre toxicology20070101

Title: Role for non-proteolytic control of M-phase-promoting factor activity at M-phase exit.

Journal: PloS one20070101

Title: The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription.

Journal: Annual review of biochemistry20070101

Title: Differential response of lymphatic, venous and arterial endothelial cells to angiopoietin-1 and angiopoietin-2.

Journal: BMC cell biology20070101

Title: Analysis of proteins binding to the ITAM motif of the beta-subunit of the high-affinity receptor for IgE (FcepsilonRI).

Journal: Journal of receptor and signal transduction research20070101

Title: Breakage-reunion domain of Streptococcus pneumoniae topoisomerase IV: crystal structure of a gram-positive quinolone target.

Journal: PloS one20070101

Title: Tyr66 acts as a conformational switch in the closed-to-open transition of the SHP-2 N-SH2-domain phosphotyrosine-peptide binding cleft.

Journal: BMC structural biology20070101

Title: Control of PDGF-induced reactive oxygen species (ROS) generation and signal transduction in human lens epithelial cells.

Journal: Molecular vision20070101

Title: [Role of c-Jun NH (2)-terminal kinase in insulin resistance after burn].

Journal: Zhonghua wai ke za zhi [Chinese journal of surgery]20070101

Title: Role of ubiquitination in IGF-1 receptor signaling and degradation.

Journal: PloS one20070101

Title: Flexible mapping of homology onto structure with homolmapper.

Journal: BMC bioinformatics20070101

Title: An insight into the sialome of the oriental rat flea, Xenopsylla cheopis (Rots).

Journal: BMC genomics20070101

Title: Reversible protein tyrosine phosphorylation affects pollen germination and pollen tube growth via the actin cytoskeleton.

Journal: Protoplasma20070101

Title: Genomic analysis of human lung fibroblasts exposed to vanadium pentoxide to identify candidate genes for occupational bronchitis.

Journal: Respiratory research20070101

Title: Quantitative proteomic analysis of phosphotyrosine-mediated cellular signaling networks.

Journal: Methods in molecular biology (Clifton, N.J.)20070101

Title: Chemoenzymatic enrichment of phosphotyrosine-containing peptides.

Journal: Angewandte Chemie (International ed. in English)20070101

Title: STATc is a key regulator of the transcriptional response to hyperosmotic shock.

Journal: BMC genomics20070101

Title: Functional and biological properties of the nuclear receptor coregulator PELP1/MNAR.

Journal: Nuclear receptor signaling20070101

Title: Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer.

Journal: Breast cancer research : BCR20070101

Title: Regulation of p73 by Hck through kinase-dependent and independent mechanisms.

Journal: BMC molecular biology20070101

Title: Malarial pigment haemozoin, IFN-gamma, TNF-alpha, IL-1beta and LPS do not stimulate expression of inducible nitric oxide synthase and production of nitric oxide in immuno-purified human monocytes.

Journal: Malaria journal20070101

Title: Mammalian sperm capacitation: role of phosphotyrosine proteins.

Journal: Society of Reproduction and Fertility supplement20070101

Title: Cyclic AMP signalling pathways in the regulation of uterine relaxation.

Journal: BMC pregnancy and childbirth20070101

Title: Evolutionary history and functional implications of protein domains and their combinations in eukaryotes.

Journal: Genome biology20070101

Title: Neurite outgrowth on a fibronectin isoform expressed during peripheral nerve regeneration is mediated by the interaction of paxillin with alpha4beta1 integrins.

Journal: BMC neuroscience20070101

Title: Tyrosine phosphatases such as SHP-2 act in a balance with Src-family kinases in stabilization of postsynaptic clusters of acetylcholine receptors.

Journal: BMC neuroscience20070101

Title: B and T lymphocyte attenuator interacts with CD3zeta and inhibits tyrosine phosphorylation of TCRzeta complex during T-cell activation.

Journal: Immunology and cell biology20070101

Title: Protein-tyrosine kinase activity profiling in knock down zebrafish embryos.

Journal: PloS one20070101

Title: Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival.

Journal: Retrovirology20070101

Title: Role of IRS and PHIP on insulin-induced tyrosine phosphorylation and distribution of IRS proteins.

Journal: Cell structure and function20070101

Title: Altered T-cell function in schizophrenia: a cellular model to investigate molecular disease mechanisms.

Journal: PloS one20070101

Title: Analysis of the Rana catesbeiana tadpole tail fin proteome and phosphoproteome during T3-induced apoptosis: identification of a novel type I keratin.

Journal: BMC developmental biology20070101

Title: Heregulin beta1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells.

Journal: Breast cancer research : BCR20070101

Title: UDP-acetyl-mannosamine dehydrogenase is an endogenous protein substrate of Staphylococcus aureus protein-tyrosine kinase activity.

Journal: Journal of molecular microbiology and biotechnology20070101

Title: MOZ-TIF2 repression of nuclear receptor-mediated transcription requires multiple domains in MOZ and in the CID domain of TIF2.

Journal: Molecular cancer20070101

Title: Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein.

Journal: BMC cancer20070101

Title: Microbial proteomics: a mass spectrometry primer for biologists.

Journal: Microbial cell factories20070101

Title: Multiple domain insertions and losses in the evolution of the Rab prenylation complex.

Journal: BMC evolutionary biology20070101

Title: A microarray strategy for mapping the substrate specificity of protein tyrosine phosphatase.

Journal: Angewandte Chemie (International ed. in English)20070101

Title: Fc gamma RII activation induces cell surface ceramide production which participates in the assembly of the receptor signaling complex.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20070101

Title: Neuregulin3 alters cell fate in the epidermis and mammary gland.

Journal: BMC developmental biology20070101

Title: Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation.

Journal: BMC structural biology20070101

Title: Developmental expression and differentiation-related neuron-specific splicing of metastasis suppressor 1 (Mtss1) in normal and transformed cerebellar cells.

Journal: BMC developmental biology20070101

Title: Nilotinib treatment in mouse models of P190 Bcr/Abl lymphoblastic leukemia.

Journal: Molecular cancer20070101

Title: Increased T-cell reactivity and elevated levels of CD8+ memory T-cells in Alzheimer's disease-patients and T-cell hyporeactivity in an Alzheimer's disease-mouse model: implications for immunotherapy.

Journal: Neuromolecular medicine20070101

Title: [Growth factors of the EGF family and their receptors].

Journal: Bulletin du cancer20070101

Title: Mechanism of homocysteine-induced Rac1/NADPH oxidase activation in mesangial cells: role of guanine nucleotide exchange factor Vav2.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20070101

Title: Activation of FAK/PI3K/Rac1 signaling controls actin reorganization and inhibits cell motility in human cancer cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20070101

Title: Syk-mediated translocation of PI3Kdelta to the leading edge controls lamellipodium formation and migration of leukocytes.

Journal: PloS one20070101

Title: Dermal fibroblasts derived from fetal and postnatal humans exhibit distinct responses to insulin like growth factors.

Journal: BMC developmental biology20070101

Title: UV-B-induced signaling events leading to enhanced-production of catharanthine in Catharanthus roseus cell suspension cultures.

Journal: BMC plant biology20070101

Title: Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6.

Journal: Breast cancer research : BCR20070101

Title: Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses.

Journal: Molecular systems biology20070101

Title: Inhibition of cell motility by troglitazone in human ovarian carcinoma cell line.

Journal: BMC cancer20070101

Title: HIV-1 Nef employs two distinct mechanisms to modulate Lck subcellular localization and TCR induced actin remodeling.

Journal: PloS one20070101

Title: PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites.

Journal: Genome biology20070101

Title: The TriTryp phosphatome: analysis of the protein phosphatase catalytic domains.

Journal: BMC genomics20070101

Title: The Fer tyrosine kinase regulates an axon retraction response to Semaphorin 3A in dorsal root ganglion neurons.

Journal: BMC developmental biology20070101

Title: Diversity and evolution of phycobilisomes in marine Synechococcus spp.: a comparative genomics study.

Journal: Genome biology20070101

Title: Glutathione-S-transferase protects against oxidative injury of endothelial cell tight junctions.

Journal: Endothelium : journal of endothelial cell research20070101

Title: Infection of mature dendritic cells with herpes simplex virus type 1 interferes with the interferon signaling pathway.

Journal: Immunobiology20070101

Title: Stress preconditioning of spreading depression in the locust CNS.

Journal: PloS one20070101

Title: Lipid rafts and caveolae in signaling by growth factor receptors.

Journal: The open biochemistry journal20070101

Title: Protein Tyrosine Phosphatase Gamma (PTPgamma) is a Novel Leukocyte Marker Highly Expressed by CD34 Precursors.

Journal: Biomarker insights20070101

Title: Computational systems biology in cancer: modeling methods and applications.

Journal: Gene regulation and systems biology20070101

Title: Tyrosine phosphatase and cytochrome P450 activity are critical in regulating store-operated calcium channels in human fibroblasts.

Journal: Experimental & molecular medicine20061231

Title: Using enzymatic reactions to enhance the photodynamic therapy effect of porphyrin dityrosine phosphates.

Journal: Chemical communications (Cambridge, England)20061228

Title: Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia.

Journal: Blood20061215

Title: Nuclear localization of PTEN is regulated by Ca(2+) through a tyrosil phosphorylation-independent conformational modification in major vault protein.

Journal: Cancer research20061215

Title: Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain.

Journal: Genes & development20061215

Title: p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration.

Journal: The EMBO journal20061213

Title: Extracellular heat shock protein 70 mediates heat stress-induced epidermal growth factor receptor transactivation in A431 carcinoma cells.

Journal: FEBS letters20061211

Title: Regulation of catalysis by the smallpox virus topoisomerase.

Journal: The Journal of biological chemistry20061208

Title: Improvement of peripheral endothelial dysfunction by protein tyrosine phosphatase inhibitors in heart failure.

Journal: Circulation20061205

Title: Leishmania amazonensis: characterization of an ecto-phosphatase activity.

Journal: Experimental parasitology20061201

Title: RET oncoproteins induce tyrosine phosphorylation changes of proteins involved in RNA metabolism.

Journal: Cellular signalling20061201

Title: TNF-alpha increases tyrosine phosphorylation of vascular endothelial cadherin and opens the paracellular pathway through fyn activation in human lung endothelia.

Journal: American journal of physiology. Lung cellular and molecular physiology20061201

Title: Decreased protein tyrosine phosphorylation and membrane fluidity in spermatozoa from infertile men with varicocele.

Journal: Molecular reproduction and development20061201

Title: Isolation and biochemical characteristics of a molecular form of epididymal acid phosphatase of boar seminal plasma.

Journal: Theriogenology20061201

Title: Activated c-Fms recruits Vav and Rac during CSF-1-induced cytoskeletal remodeling and spreading in osteoclasts.

Journal: Bone20061201

Title: Avian reovirus activates a novel proapoptotic signal by linking Src to p53.

Journal: Apoptosis : an international journal on programmed cell death20061201

Title: Control of neuronal excitability by phosphorylation and dephosphorylation of sodium channels.

Journal: Biochemical Society transactions20061201

Title: Identification and functional characterization of an Src homology domain 3 domain-binding site on Cbl.

Journal: The FEBS journal20061201

Title: Hypoglycemic effects of vanadium on alloxan monohydrate induced diabetic dogs.

Journal: Journal of veterinary science20061201

Title: Tyrosine phosphorylation controls PCNA function through protein stability.

Journal: Nature cell biology20061201

Title: A role for p130Cas in mechanotransduction.

Journal: Cell20061201

Title: Force sensing by mechanical extension of the Src family kinase substrate p130Cas.

Journal: Cell20061201

Title: Activation of T lymphocytes and the role of the adapter LAT.

Journal: Transplant immunology20061201

Title: Effect of glucocorticoid-induced osteoporotic-like conditions on osteoblast cell attachment to implant surface microtopographies.

Journal: Implant dentistry20061201

Title: Alterations in protein tyrosine kinase pathways in rat liver following normothermic ischemia-reperfusion.

Journal: Transplantation proceedings20061201

Title: Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.

Journal: PLoS medicine20061201

Title: A new fragmentation rearrangement of the N-terminal protected amino acids using ESI-MS/MS.

Journal: Indian journal of biochemistry & biophysics20061201

Title: [Amelioration of insulin resistance after scald by c-Jun N-terminal kinase inhibitor in rat].

Journal: Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns20061201

Title: Role of erlotinib in the management of pancreatic cancer.

Journal: Therapeutics and clinical risk management20061201

Title: Oxyhemoglobin-induced suppression of voltage-dependent K+ channels in cerebral arteries by enhanced tyrosine kinase activity.

Journal: Circulation research20061124

Title: Brain-derived neurotrophic factor rapidly increases NMDA receptor channel activity through Fyn-mediated phosphorylation.

Journal: Brain research20061122

Title: DAB1 and Reelin effects on amyloid precursor protein and ApoE receptor 2 trafficking and processing.

Journal: The Journal of biological chemistry20061117

Title: SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20061115

Title: Conditional deletion of Shp2 in the mammary gland leads to impaired lobulo-alveolar outgrowth and attenuated Stat5 activation.

Journal: The Journal of biological chemistry20061110

Title: Shift syndecan-2 from RACK1 to caveolin-2 upon transformation with oncogenic ras.

Journal: Biochemical and biophysical research communications20061110

Title: Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells.

Journal: British journal of cancer20061106

Title: Elevated activity of STAT3C due to higher DNA binding affinity of phosphotyrosine dimer rather than covalent dimer formation.

Journal: The Journal of biological chemistry20061103

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

Journal: Cell20061103

Title: Clinically relevant doses of fluoxetine and reboxetine induce changes in the TrkB content of central excitatory synapses.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology20061101

Title: Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells.

Journal: American journal of physiology. Endocrinology and metabolism20061101

Title: Insulin-like growth factor-I induces alpha(1B)-adrenergic receptor phosphorylation through G beta gamma and epidermal growth factor receptor transactivation.

Journal: Molecular endocrinology (Baltimore, Md.)20061101

Title: Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis.

Journal: American journal of physiology. Cell physiology20061101

Title: Impaired neutrophil chemotaxis in sepsis associates with GRK expression and inhibition of actin assembly and tyrosine phosphorylation.

Journal: Blood20061101

Title: A new marine-derived sulfated polysaccharide from brown alga suppresses tumor metastasis both in vitro and in vivo.

Journal: Cancer biology & therapy20061101

Title: Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils.

Journal: Nature cell biology20061101

Title: Characterization of ecto-phosphatase activities of Trypanosoma cruzi: a comparative study between Colombiana and Y strains.

Journal: Acta tropica20061101

Title: Receptor cross-linking on human plasmacytoid dendritic cells leads to the regulation of IFN-alpha production.

Journal: Journal of immunology (Baltimore, Md. : 1950)20061101

Title: Cbl-b is a negative regulator of inflammatory cytokines produced by IgE-activated mast cells.

Journal: Journal of immunology (Baltimore, Md. : 1950)20061101

Title: Optimization of the cellular import of functionally active SH2-domain-interacting phosphopeptides.

Journal: Cellular and molecular life sciences : CMLS20061101

Title: Human cationic trypsinogen is sulfated on Tyr154.

Journal: The FEBS journal20061101

Title: Cardiovascular effects of nickel in ambient air.

Journal: Environmental health perspectives20061101

Title: Enhancement of insulin signaling pathway in adipocytes by oxovanadium(IV) complexes.

Journal: Biochemical and biophysical research communications20061027

Title: Csk-binding protein mediates sequential enzymatic down-regulation and degradation of Lyn in erythropoietin-stimulated cells.

Journal: The Journal of biological chemistry20061020

Title: Structure-based design of potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics.

Journal: Biochemical and biophysical research communications20061020

Title: Unique role of SNT-2/FRS2beta/FRS3 docking/adaptor protein for negative regulation in EGF receptor tyrosine kinase signaling pathways.

Journal: Oncogene20061019

Title: High-throughput kinase assay based on surface plasmon resonance suitable for native protein substrates.

Journal: Analytical biochemistry20061015

Title: In situ phosphorylation of immobilized receptors on biosensor surfaces: application to E-cadherin/beta-catenin interactions.

Journal: Analytical biochemistry20061015

Title: ReSETting PP2A tumour suppressor activity in blast crisis and imatinib-resistant chronic myelogenous leukaemia.

Journal: British journal of cancer20061009

Title: Engineering the recruitment of phosphotyrosine binding domain-containing adaptor proteins reveals distinct roles for RET receptor-mediated cell survival.

Journal: The Journal of biological chemistry20061006

Title: The tyrosine kinase c-Abl protects c-Jun from ubiquitination-mediated degradation in T cells.

Journal: The Journal of biological chemistry20061006

Title: Action of TFII-I outside the nucleus as an inhibitor of agonist-induced calcium entry.

Journal: Science (New York, N.Y.)20061006

Title: Ligand-independent and EGF receptor-supported transactivation: lessons from beta2-adrenergic receptor signalling.

Journal: Cellular signalling20061001

Title: Cell surface beta 1, 4-galactosyltransferase 1 promotes apoptosis by inhibiting epidermal growth factor receptor pathway.

Journal: Molecular and cellular biochemistry20061001

Title: Focal adhesion and actin organization by a cross-talk of TM4SF5 with integrin alpha2 are regulated by serum treatment.

Journal: Experimental cell research20061001

Title: Fibroblast growth factor-2 induces the activation of Src through Fes, which regulates focal adhesion disassembly.

Journal: Experimental cell research20061001

Title: A global proteomics approach identifies novel phosphorylated signaling proteins in GPVI-activated platelets: involvement of G6f, a novel platelet Grb2-binding membrane adapter.

Journal: Proteomics20061001

Title: Focal adhesion kinase signaling at sites of integrin-mediated adhesion controls axon pathfinding.

Journal: Nature neuroscience20061001

Title: Hypophosphorylation of residue Y1045 leads to defective downregulation of EGFRvIII.

Journal: Cancer biology & therapy20061001

Title: Dynamic quantification of the tyrosine phosphorylation of the sperm surface proteins during capacitation.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20061001

Title: Thrombin induces GPIb-IX-mediated fibrin binding to alphaIIbbeta3 in a reconstituted Chinese hamster ovary cell model.

Journal: Journal of thrombosis and haemostasis : JTH20061001

Title: Role of Rac1 in fibronectin-induced adhesion and motility of human corneal epithelial cells.

Journal: Investigative ophthalmology & visual science20061001

Title: Effect of five triterpenoid compounds from the buds of Aralia elata on stimulus-induced superoxide generation, tyrosyl phosphorylation and translocation of cytosolic compounds to the cell membrane in human neutrophils.

Journal: Planta medica20061001

Title: Phosphotyrosine signaling in platelets: lessons for vascular thrombosis.

Journal: Current drug targets20061001

Title: CD45 isoform expression in microglia and inflammatory cells in HIV-1 encephalitis.

Journal: Brain pathology (Zurich, Switzerland)20061001

Title: Expression of the SNT-1/FRS2 phosphotyrosine binding domain inhibits activation of MAP kinase and PI3-kinase pathways and antiestrogen resistant growth induced by FGF-1 in human breast carcinoma cells.

Journal: Oncogene20060928

Title: Involvement of insulin-like growth factor type 1 receptor and protein kinase Cdelta in bis(maltolato)oxovanadium(IV)-induced phosphorylation of protein kinase B in HepG2 cells.

Journal: Biochemistry20060926

Title: Synthetic D-amino acid peptide inhibits tumor cell motility on laminin-5.

Journal: Carcinogenesis20060901

Title: Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane.

Journal: Journal of cellular physiology20060901

Title: Isothiazolidinone heterocycles as inhibitors of protein tyrosine phosphatases: synthesis and structure-activity relationships of a peptide scaffold.

Journal: Bioorganic & medicinal chemistry20060901

Title: Hexose-specificity of hexokinase and ADP-dependence of pyruvate kinase play important roles in the control of monosaccharide utilization in freshly diluted boar spermatozoa.

Journal: Molecular reproduction and development20060901

Title: Identification and characterization of NYGGF4, a novel gene containing a phosphotyrosine-binding (PTB) domain that stimulates 3T3-L1 preadipocytes proliferation.

Journal: Gene20060901

Title: Chromium and vanadate combination increases insulin-induced glucose uptake by 3T3-L1 adipocytes.

Journal: Biochemical and biophysical research communications20060901

Title: Binding of sialyl Lewis X antigen to lectin-like receptors on NK cells induces cytotoxicity and tyrosine phosphorylation of a 17-kDa protein.

Journal: Biochimica et biophysica acta20060901

Title: Photoreceptor morphogenesis in the Drosophila compound eye: R1-R6 rhabdomeres become twisted just before eclosion.

Journal: The Journal of comparative neurology20060901

Title: Sodium orthovanadate induced tyrosine phosphorylation of platelet nitric oxide synthase negatively regulates enzyme activity.

Journal: Biochimica et biophysica acta20060901

Title: Identification of a tyrosine-phosphorylated CCCTC-binding nuclear factor in capacitated mouse spermatozoa.

Journal: Proteomics20060901

Title: Cool-1 functions as an essential regulatory node for EGF receptor- and Src-mediated cell growth.

Journal: Nature cell biology20060901

Title: Molecular and functional characterization of CD300b, a new activating immunoglobulin receptor able to transduce signals through two different pathways.

Journal: Journal of immunology (Baltimore, Md. : 1950)20060901

Title: Mutational analysis of the mechanism of negative regulation by SRC homology 2 domain-containing protein tyrosine phosphatase substrate-1 of phagocytosis in macrophages.

Journal: Journal of immunology (Baltimore, Md. : 1950)20060901

Title: Characterization of a tyrosine phosphatase activity in the oogenesis of Periplaneta americana.

Journal: Archives of insect biochemistry and physiology20060901

Title: Identification of radiation-induced cross-linking between thymine and tryptophan by electrospray ionization-mass spectrometry.

Journal: Journal of mass spectrometry : JMS20060901

Title: Quantitative multiplexed profiling of cellular signaling networks using phosphotyrosine-specific DNA-tagged SH2 domains.

Journal: Nature methods20060901

Title: Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote.

Journal: PLoS biology20060901

Title: Crystallization and preliminary X-ray diffraction analysis of rat protein tyrosine phosphatase eta.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications20060901

Title: Solution structure and phosphopeptide binding of the SH2 domain from the human Bruton's tyrosine kinase.

Journal: Journal of biomolecular NMR20060901

Title: Integration of P2Y receptor-activated signal transduction pathways in G protein-dependent signalling networks.

Journal: Purinergic signalling20060901

Title: A cationic lanthanide complex binds selectively to phosphorylated tyrosine sites, aiding NMR analysis of the phosphorylated insulin receptor peptide fragment.

Journal: Organic & biomolecular chemistry20060821

Title: Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.

Journal: Bioorganic & medicinal chemistry letters20060815

Title: Structural basis for phosphotyrosine recognition by the Src homology-2 domains of the adapter proteins SH2-B and APS.

Journal: Journal of molecular biology20060804

Title: Lck couples Shc to TCR signaling.

Journal: Cellular signalling20060801

Title: Activation of Epstein-Barr virus/C3d receptor (gp140, CR2, CD21) on human B lymphoma cell surface triggers Cbl tyrosine phosphorylation, its association with p85 subunit, Crk-L and Syk and its dissociation with Vav.

Journal: Cellular signalling20060801

Title: Regulation of Stat3 nuclear import by importin alpha5 and importin alpha7 via two different functional sequence elements.

Journal: Cellular signalling20060801

Title: Phosphoregulation of signal transduction pathways in ischemia and reperfusion.

Journal: The Journal of surgical research20060801

Title: Bifunctional role of the leishmanial antimonate reductase LmACR2 as a protein tyrosine phosphatase.

Journal: Molecular and biochemical parasitology20060801

Title: Functional proteomics identifies protein-tyrosine phosphatase 1B as a target of RhoA signaling.

Journal: Molecular & cellular proteomics : MCP20060801

Title: Dynamics of the WPD loop of the Yersinia protein tyrosine phosphatase.

Journal: Biophysical journal20060801

Title: 15-Deoxy-delta12,14-prostaglandin J2 regulates leukemia inhibitory factor signaling through JAK-STAT pathway in mouse embryonic stem cells.

Journal: Experimental cell research20060801

Title: Angiotensin II type 2 receptor-bradykinin B2 receptor functional heterodimerization.

Journal: Hypertension (Dallas, Tex. : 1979)20060801

Title: Signal transduction in endothelial cells by the angiogenesis inhibitor histidine-rich glycoprotein targets focal adhesions.

Journal: Experimental cell research20060801

Title: Downregulation of the PI3K/Akt survival pathway in cells with deregulated expression of c-Myc.

Journal: Apoptosis : an international journal on programmed cell death20060801

Title: Membrane and juxtamembrane targeting by PH and PTB domains.

Journal: Biochimica et biophysica acta20060801

Title: Low-molecular-weight chromium-binding substance from chicken liver and American alligator liver.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology20060801

Title: The Rap GTPases mediate CXCL13- and sphingosine1-phosphate-induced chemotaxis, adhesion, and Pyk2 tyrosine phosphorylation in B lymphocytes.

Journal: European journal of immunology20060801

Title: Profilin tyrosine phosphorylation in poly-L-proline-binding regions inhibits binding to phosphoinositide 3-kinase in Phaseolus vulgaris.

Journal: The Plant journal : for cell and molecular biology20060801

Title: Negative regulation of ERK activity by VRK3-mediated activation of VHR phosphatase.

Journal: Nature cell biology20060801

Title: New prospects for an old enzyme: mammalian cytochrome c is tyrosine-phosphorylated in vivo.

Journal: Biochemistry20060801

Title: Temporal dynamics of tyrosine phosphorylation in insulin signaling.

Journal: Diabetes20060801

Title: A pseudosymmetric cell adhesion regulatory domain in the beta7 tail of the integrin alpha4beta7 that interacts with focal adhesion kinase and src.

Journal: European journal of immunology20060801

Title: Phosphopeptide ligands of the SHP-1 N-SH2 domain: effects on binding and stimulation of phosphatase activity.

Journal: ChemMedChem20060801

Title: Structural basis for phosphotyrosine recognition by suppressor of cytokine signaling-3.

Journal: Structure (London, England : 1993)20060801

Title: Structure and mechanism of the phosphotyrosyl phosphatase activator.

Journal: Molecular cell20060801

Title: CXCR4 physically associates with the T cell receptor to signal in T cells.

Journal: Immunity20060801

Title: Endogenously generated reactive oxygen species reduce PMCA activity in platelets from patients with non-insulin-dependent diabetes mellitus.

Journal: Platelets20060801

Title: Nucleoside diphosphate kinase A as a controller of AMP-kinase in airway epithelia.

Journal: Journal of bioenergetics and biomembranes20060801

Title: Differential effects of flavonoids on bovine kidney low molecular mass protein tyrosine phosphatase.

Journal: Journal of enzyme inhibition and medicinal chemistry20060801

Title: Defective T cell receptor-mediated signal transduction in memory CD4 T lymphocytes exposed to superantigen or anti-T cell receptor antibodies.

Journal: Cellular immunology20060801

Title: Blue native polyacrylamide gel electrophoresis (BN-PAGE) for the identification and analysis of multiprotein complexes.

Journal: Science's STKE : signal transduction knowledge environment20060725

Title: Facile synthesis and application of uniformly 13C, 15N-labeled phosphotyrosine for ligand binding studies.

Journal: Bioorganic & medicinal chemistry letters20060715

Title: Involvement of the N-terminal unique domain of Chk tyrosine kinase in Chk-induced tyrosine phosphorylation in the nucleus.

Journal: Experimental cell research20060715

Title: Association of Grb-2 and PI3K p85 with phosphotyrosile peptides derived from BTLA.

Journal: Biochemical and biophysical research communications20060714

Title: Identification of phosphoproteins associated with maintenance of transformed state in temperature-sensitive Rous sarcoma-virus infected cells by proteomic analysis.

Journal: Biochemical and biophysical research communications20060707

Title: Src family tyrosine kinases differentially modulate exocytosis from rat brain nerve terminals.

Journal: Neurochemistry international20060701

Title: Continuous assay of protein tyrosine phosphatases based on fluorescence resonance energy transfer.

Journal: Biochimie20060701

Title: B cell antigen receptor signaling and internalization are mutually exclusive events.

Journal: PLoS biology20060701

Title: Tyrosine phosphorylated proteins in the reproductive tract of the viviparous lizard Eulamprus tympanum and the oviparous lizard Lampropholis guichenoti.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology20060701

Title: SRC-family tyrosine kinases in wound- and ligand-induced epidermal growth factor receptor activation in human corneal epithelial cells.

Journal: Investigative ophthalmology & visual science20060701

Title: VEGF expression and receptor activation in the choroid during development and in the adult.

Journal: Investigative ophthalmology & visual science20060701

Title: Two membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signaling.

Journal: PLoS genetics20060701

Title: Macrophage pro-inflammatory response to Francisella novicida infection is regulated by SHIP.

Journal: PLoS pathogens20060701

Title: [Detection of phosphotyrosine in bcr-abl-positive cells with PY20 antibody and its clinical applications].

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi20060701

Title: The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.

Journal: The Journal of biological chemistry20060630

Title: Potent benzimidazole sulfonamide protein tyrosine phosphatase 1B inhibitors containing the heterocyclic (S)-isothiazolidinone phosphotyrosine mimetic.

Journal: Journal of medicinal chemistry20060629

Title: The human and mouse complement of SH2 domain proteins-establishing the boundaries of phosphotyrosine signaling.

Journal: Molecular cell20060623

Title: NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity.

Journal: The EMBO journal20060621

Title: Conformational analysis of gamma' peptide (410-427) interactions with thrombin anion binding exosite II.

Journal: Biochemistry20060620

Title: A loss of c-kit expression is associated with an advanced stage and poor prognosis in breast cancer.

Journal: British journal of cancer20060619

Title: A common phosphotyrosine signature for the Bcr-Abl kinase.

Journal: Blood20060615

Title: Crotoxin induces actin reorganization and inhibits tyrosine phosphorylation and activity of small GTPases in rat macrophages.

Journal: Toxicon : official journal of the International Society on Toxinology20060615

Title: The relation between survival and expression of HER1 and HER2 depends on the expression of HER3 and HER4: a study in bladder cancer patients.

Journal: British journal of cancer20060605

Title: Vascular endothelial growth factor receptor-1 mediates migration of human colorectal carcinoma cells by activation of Src family kinases.

Journal: British journal of cancer20060605

Title: Collagen type I selectively activates ectodomain shedding of the discoidin domain receptor 1: involvement of Src tyrosine kinase.

Journal: Journal of cellular biochemistry20060601

Title: Adhesion and proliferation of fibroblasts on RF plasma-deposited nanostructured fluorocarbon coatings: evidence of FAK activation.

Journal: Journal of cellular physiology20060601

Title: Effects of seawater pollutants on protein tyrosine phosphorylation in mussel tissues.

Journal: Aquatic toxicology (Amsterdam, Netherlands)20060601

Title: Quinolinic acid modulates the activity of src family kinases in rat striatum: in vivo and in vitro studies.

Journal: Journal of neurochemistry20060601

Title: Eph receptors are negatively controlled by protein tyrosine phosphatase receptor type O.

Journal: Nature neuroscience20060601

Title: The enteropathogenic Escherichia coli EspF effector molecule inhibits PI-3 kinase-mediated uptake independently of mitochondrial targeting.

Journal: Cellular microbiology20060601

Title: Activation of p38 mitogen-activated protein kinase promotes epidermal growth factor receptor internalization.

Journal: Traffic (Copenhagen, Denmark)20060601

Title: Structure of human DSP18, a member of the dual-specificity protein tyrosine phosphatase family.

Journal: Acta crystallographica. Section D, Biological crystallography20060601

Title: B and T lymphocyte attenuator-mediated signal transduction provides a potent inhibitory signal to primary human CD4 T cells that can be initiated by multiple phosphotyrosine motifs.

Journal: Journal of immunology (Baltimore, Md. : 1950)20060601

Title: Design and synthesis of phosphotyrosine peptidomimetic prodrugs.

Journal: Journal of medicinal chemistry20060601

Title: The larval development of the telotrophic meroistic ovary in the bug Dysdercus intermedius (Heteroptera, Pyrrhocoridae).

Journal: Arthropod structure & development20060601

Title: Structural basis for the phosphorylation-regulated focal adhesion targeting of type Igamma phosphatidylinositol phosphate kinase (PIPKIgamma) by talin.

Journal: Journal of molecular biology20060526

Title: The elucidation of novel SH2 binding sites on PLD2.

Journal: Oncogene20060518

Title: A kinase independent function for Tec kinase ITK in regulating antigen receptor induced serum response factor activation.

Journal: FEBS letters20060515

Title: Increased Src kinase level results in increased protein tyrosine phosphorylation in scrapie-infected neuronal cell lines.

Journal: FEBS letters20060515

Title: Major groove interactions of vaccinia Topo I provide specificity by optimally positioning the covalent phosphotyrosine linkage.

Journal: Biochemistry20060509

Title: Tyrosine phosphorylation is required for functional activation of disulfide-containing constitutively active STAT mutants.

Journal: Biochemistry20060502

Title: Lysophosphatidic acid-induced effects in human colon carcinoma DLD1 cells are partially dependent on transactivation of epidermal growth factor receptor.

Journal: The Journal of surgical research20060501

Title: Sialylation regulates peripheral tolerance in CD4+ T cells.

Journal: International immunology20060501

Title: Quantitative kinetic analysis of gene expression during human osteoblastic adhesion on orthopaedic materials.

Journal: Biomaterials20060501

Title: Co-localization of cortactin and phosphotyrosine identifies active invadopodia in human breast cancer cells.

Journal: Experimental cell research20060501

Title: Src homology 2 domain-based high throughput assays for profiling downstream molecules in receptor tyrosine kinase pathways.

Journal: Molecular & cellular proteomics : MCP20060501

Title: The protein tyrosine phosphatase, Shp2, is required for the complete activation of the RAS/MAPK pathway by brain-derived neurotrophic factor.

Journal: Journal of neurochemistry20060501

Title: Microfabricated discontinuous-edge surface topographies influence osteoblast adhesion, migration, cytoskeletal organization, and proliferation and enhance matrix and mineral deposition in vitro.

Journal: Calcified tissue international20060501

Title: APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function.

Journal: Nature cell biology20060501

Title: Doxycycline alters vascular smooth muscle cell adhesion, migration, and reorganization of fibrillar collagen matrices.

Journal: The American journal of pathology20060501

Title: 2-D DIGE analysis of butyrate-treated HCT-116 cells after enrichment with heparin affinity chromatography.

Journal: Journal of proteome research20060501

Title: Grasp a pTyr-peptide by its SOCS.

Journal: Developmental cell20060501

Title: Formation of focal adhesion-like structures in circulating human neutrophils after severe injury: triggering of a tissue-phase response in the vascular space.

Journal: Shock (Augusta, Ga.)20060501

Title: The leukocyte receptor complex in chicken is characterized by massive expansion and diversification of immunoglobulin-like Loci.

Journal: PLoS genetics20060501

Title: Co expression of SCF and KIT in gastrointestinal stromal tumours (GISTs) suggests an autocrine/paracrine mechanism.

Journal: British journal of cancer20060424

Title: Climbing the Greatwall to mitosis.

Journal: Molecular cell20060421

Title: The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.

Journal: Molecular cell20060421

Title: Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes.

Journal: Nature20060406

Title: Dependence of tryptophan emission wavelength on conformation in cyclic hexapeptides.

Journal: The journal of physical chemistry. B20060406

Title: Negative regulation of a protein tyrosine phosphatase by tyrosine phosphorylation.

Journal: Journal of the American Chemical Society20060405

Title: Albumin induces cellular fibrosis by upregulating transforming growth factor-beta ligand and its receptors in renal distal tubule cells.

Journal: Journal of cellular biochemistry20060401

Title: Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors.

Journal: Bioorganic & medicinal chemistry20060401

Title: Oncogenic Met receptor induces cell-cycle progression in Xenopus oocytes independent of direct Grb2 and Shc binding or Mos synthesis, but requires phosphatidylinositol 3-kinase and Raf signaling.

Journal: Journal of cellular physiology20060401

Title: Core erythropoietin receptor signals for late erythroblast development.

Journal: Blood20060401

Title: Nitric oxide attenuates IGF-I-induced aortic smooth muscle cell motility by decreasing Rac1 activity: essential role of PTP-PEST and p130cas.

Journal: American journal of physiology. Cell physiology20060401

Title: The molecular dynamics of osteoclast adhesions.

Journal: European journal of cell biology20060401

Title: Blockade of interleukin-13-mediated cell activation by a novel inhibitory antibody to human IL-13 receptor alpha1.

Journal: Molecular immunology20060401

Title: Reactive oxygen species generation is involved in epidermal growth factor receptor transactivation through the transient oxidization of Src homology 2-containing tyrosine phosphatase in endothelin-1 signaling pathway in rat cardiac fibroblasts.

Journal: Molecular pharmacology20060401

Title: Tyrosine phosphorylation on capacitated human sperm tail detected by immunofluorescence correlates strongly with sperm-zona pellucida (ZP) binding but not with the ZP-induced acrosome reaction.

Journal: Human reproduction (Oxford, England)20060401

Title: Prenatal MgSO4 treatment modifies the erythrocyte band 3 in preterm neonates.

Journal: Pharmacological research20060401

Title: Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways.

Journal: Trends in cell biology20060401

Title: Proteomic analysis reveals novel molecules involved in insulin signaling pathway.

Journal: Journal of proteome research20060401

Title: Inhibition of phosphotyrosine phosphatase 1B causes resistance in BCR-ABL-positive leukemia cells to the ABL kinase inhibitor STI571.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20060401

Title: Effect of brassinolide on tyrosine phosphorylation of pea leaf proteins.

Journal: Biochemistry. Biokhimiia20060401

Title: Subcellular fractionation reveals proteins involved in insulin signaling.

Journal: Journal of proteome research20060401

Title: Metallothionein antagonizes aging-induced cardiac contractile dysfunction: role of PTP1B, insulin receptor tyrosine phosphorylation and Akt.

Journal: Aging cell20060401

Title: Altered expression, localization, and phosphorylation of epithelial junctional proteins in celiac disease.

Journal: American journal of clinical pathology20060401

Title: Conformational changes in protein loops and helices induced by post-translational phosphorylation.

Journal: PLoS computational biology20060401

Title: Evolution of cytokine responses: IL-1beta directly affects intracellular Ca2+ concentration of teleost fish leukocytes through a receptor-mediated mechanism.

Journal: Cytokine20060401

Title: Identification of integrin alpha1 as an interacting protein of protein tyrosine phosphatase PRL-3.

Journal: Biochemical and biophysical research communications20060331

Title: Alterations in intracellular calcium homeostasis and platelet aggregation induced by ethanol.

Journal: Biochemical and biophysical research communications20060324

Title: Dimerization is required for SH3PX1 tyrosine phosphorylation in response to epidermal growth factor signalling and interaction with ACK2.

Journal: The Biochemical journal20060315

Title: 1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors.

Journal: Bioorganic & medicinal chemistry letters20060315

Title: Pancreatitis-associated protein I suppresses NF-kappa B activation through a JAK/STAT-mediated mechanism in epithelial cells.

Journal: Journal of immunology (Baltimore, Md. : 1950)20060315

Title: JAK/STAT signal transduction: regulators and implication in hematological malignancies.

Journal: Biochemical pharmacology20060314

Title: Crystal structure of the human B-form low molecular weight phosphotyrosyl phosphatase at 1.6-A resolution.

Journal: The Journal of biological chemistry20060310

Title: A peroxisome proliferator-activated receptor-gamma agonist, troglitazone, facilitates caspase-8 and -9 activities by increasing the enzymatic activity of protein-tyrosine phosphatase-1B on human glioma cells.

Journal: The Journal of biological chemistry20060310

Title: Structural basis for the requirement of two phosphotyrosine residues in signaling mediated by Syk tyrosine kinase.

Journal: Journal of molecular biology20060310

Title: Discovery of a novel nonphosphorylated pentapeptide motif displaying high affinity for Grb2-SH2 domain by the utilization of 3'-substituted tyrosine derivatives.

Journal: Journal of medicinal chemistry20060309

Title: Using a kinase/phosphatase switch to regulate a supramolecular hydrogel and forming the supramolecular hydrogel in vivo.

Journal: Journal of the American Chemical Society20060308

Title: SOCS1 inhibits tumor necrosis factor-induced activation of ASK1-JNK inflammatory signaling by mediating ASK1 degradation.

Journal: The Journal of biological chemistry20060303

Title: Chemical rescue of a mutant enzyme in living cells.

Journal: Science (New York, N.Y.)20060303

Title: Her-2/neu and EGFR tyrosine kinase activation predict the efficacy of trastuzumab-based therapy in patients with metastatic breast cancer.

Journal: International journal of cancer20060301

Title: Hyper-osmotic condition enhances protein tyrosine phosphorylation and zona pellucida binding capacity of human sperm.

Journal: Human reproduction (Oxford, England)20060301

Title: In Saccharomyces cerevisiae an unbalanced level of tyrosine phosphorylation down-regulates the Ras/PKA pathway.

Journal: The international journal of biochemistry & cell biology20060301

Title: Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans.

Journal: PLoS medicine20060301

Title: The role of VEGF receptors in angiogenesis; complex partnerships.

Journal: Cellular and molecular life sciences : CMLS20060301

Title: Molecular mapping of tyrosine-phosphorylated proteins in focal adhesions using fluorescence resonance energy transfer.

Journal: Journal of cell science20060301

Title: Sprouty proteins are in vivo targets of Corkscrew/SHP-2 tyrosine phosphatases.

Journal: Development (Cambridge, England)20060301

Title: Quantitative analysis of phosphotyrosine signaling networks triggered by CD3 and CD28 costimulation in Jurkat cells.

Journal: Journal of immunology (Baltimore, Md. : 1950)20060301

Title: Unique structural determinants for Stat3 recruitment and activation by the granulocyte colony-stimulating factor receptor at phosphotyrosine ligands 704 and 744.

Journal: Journal of immunology (Baltimore, Md. : 1950)20060301

Title: Tick vitellin is dephosphorylated by a protein tyrosine phosphatase during egg development: effect of dephosphorylation on VT proteolysis.

Journal: Insect biochemistry and molecular biology20060301

Title: Correlation of in vitro cytokine responses with the chemical composition of soil-derived particulate matter.

Journal: Environmental health perspectives20060301

Title: Signals for stress erythropoiesis are integrated via an erythropoietin receptor-phosphotyrosine-343-Stat5 axis.

Journal: The Journal of clinical investigation20060301

Title: Quantitative phosphotyrosine proteomics of EphB2 signaling by stable isotope labeling with amino acids in cell culture (SILAC).

Journal: Journal of proteome research20060301

Title: Dissection of a functional interaction between the DNA translocase, FtsK, and the XerD recombinase.

Journal: Molecular microbiology20060301

Title: The dictyostelium kinome--analysis of the protein kinases from a simple model organism.

Journal: PLoS genetics20060301

Title: Phosphoinositide, phosphopeptide and pyridone interactions of the Abl SH2 domain.

Journal: Chemical biology & drug design20060301

Title: [Difference in methylation of genomic DNA between gastric primary cancer and lymph nodes with metastatic gastric cancer].

Journal: Zhonghua yi xue za zhi20060227

Title: Binding of laminin alpha1-chain LG4-5 domain to alpha-dystroglycan causes tyrosine phosphorylation of syntrophin to initiate Rac1 signaling.

Journal: Biochemistry20060221

Title: Scaffolding adapter Grb2-associated binder 2 requires Syk to transmit signals from FcepsilonRI.

Journal: Journal of immunology (Baltimore, Md. : 1950)20060215

Title: Functional hierarchy of the N-terminal tyrosines of SLP-76.

Journal: Journal of immunology (Baltimore, Md. : 1950)20060215

Title: Activation of the JAK-STAT signaling pathway in the rat basilar artery after subarachnoid hemorrhage.

Journal: Brain research20060209

Title: HGF induction of postsynaptic specializations at the neuromuscular junction.

Journal: Journal of neurobiology20060205

Title: Tryptase activates phosphatidylinositol 3-kinases proteolytically independently from proteinase-activated receptor-2 in cultured dog airway smooth muscle cells.

Journal: American journal of physiology. Lung cellular and molecular physiology20060201

Title: Similarities and differences between the E5 oncoproteins of bovine papillomaviruses type 1 and type 4: cytoskeleton, motility and invasiveness in E5-transformed bovine and mouse cells.

Journal: Virus research20060201

Title: Rapid single tube genotyping of ACP1 by FRET based amplification and dual color melting curve analysis.

Journal: Molecular and cellular probes20060201

Title: AMBER force-field parameters for phosphorylated amino acids in different protonation states: phosphoserine, phosphothreonine, phosphotyrosine, and phosphohistidine.

Journal: Journal of molecular modeling20060201

Title: Insulin receptor kinase-associated phosphotyrosine phosphatases in hepatic endosomes: assessing the role of phosphotyrosine phosphatase-1B.

Journal: Endocrinology20060201

Title: Type II phosphatidylinositol 4-kinase beta associates with TCR-CD3 zeta chain in Jurkat cells.

Journal: Molecular immunology20060201

Title: Endocytic pathways and biological effects induced by UVB-dependent or ligand-dependent activation of the keratinocyte growth factor receptor.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20060201

Title: Differential steady-state tyrosine phosphorylation of two oligomeric forms of mitochondrial F0F1ATPsynthase: a structural proteomic analysis.

Journal: Proteomics20060201

Title: Altered subcellular distribution of IRS-1 and IRS-3 is associated with defective Akt activation and GLUT4 translocation in insulin-resistant old rat adipocytes.

Journal: Biochimica et biophysica acta20060201

Title: Differential phosphoprotein mapping in cancer cells using protein microarrays produced from 2-D liquid fractionation.

Journal: Analytical chemistry20060201

Title: Effect of docosahexaenoic acid on interleukin-2 receptor signaling pathway in lipid rafts.

Journal: Science in China. Series C, Life sciences20060201

Title: Inhibition of immune responses by ITAM-bearing receptors.

Journal: Science's STKE : signal transduction knowledge environment20060131

Title: Minimal features of paxillin that are required for the tyrosine phosphorylation of focal adhesion kinase.

Journal: The Biochemical journal20060115

Title: A quantitative protein interaction network for the ErbB receptors using protein microarrays.

Journal: Nature20060112

Title: Pinpointing phosphotyrosine-dependent interactions downstream of the collagen receptor DDR1.

Journal: FEBS letters20060109

Title: The dependence of fibrillar adhesions in human fibroblasts on substratum chemistry.

Journal: Biomaterials20060101

Title: Hyperphosphorylation of JNK-interacting protein 1, a protein associated with Alzheimer disease.

Journal: Molecular & cellular proteomics : MCP20060101

Title: Molecular basis for regulation of Src by the docking protein p130Cas.

Journal: Journal of molecular recognition : JMR20060101

Title: Src activation of NF-kappaB augments IL-1beta-induced nitric oxide production in mesangial cells.

Journal: Journal of the American Society of Nephrology : JASN20060101

Title: Use of detergents to increase selectivity of immunoprecipitation of tyrosine phosphorylated peptides prior to identification by MALDI quadrupole-TOF MS.

Journal: Proteomics20060101

Title: RACK1 recruits STAT3 specifically to insulin and insulin-like growth factor 1 receptors for activation, which is important for regulating anchorage-independent growth.

Journal: Molecular and cellular biology20060101

Title: A preliminary investigation into the action of anagrelide: thrombopoietin-c-Mpl receptor interactions.

Journal: Experimental hematology20060101

Title: Genome-wide analysis and experimentation of plant serine/ threonine/tyrosine-specific protein kinases.

Journal: Plant molecular biology20060101

Title: Protein kinases associated with the yeast phosphoproteome.

Journal: BMC bioinformatics20060101

Title: The role of tyrosine phosphorylation in regulation of signal transduction pathways in unicellular eukaryotes.

Journal: Current issues in molecular biology20060101

Title: The role of water in computational and experimental derivation of binding thermodynamics in SH2 domains.

Journal: Chemical biology & drug design20060101

Title: Exploring supervised and unsupervised methods to detect topics in biomedical text.

Journal: BMC bioinformatics20060101

Title: The p38 mitogen-activated protein kinase signaling cascade in CD4 T cells.

Journal: Arthritis research & therapy20060101

Title: PPSP: prediction of PK-specific phosphorylation site with Bayesian decision theory.

Journal: BMC bioinformatics20060101

Title: Changes in membrane lipid order with capacitation in rhesus macaque (Macaca mulatta) spermatozoa.

Journal: Journal of andrology20060101

Title: Matrix metalloproteinase and tissue inhibitor of metalloproteinase in serum and synovial fluid of osteoarthritic dogs.

Journal: Veterinary and comparative orthopaedics and traumatology : V.C.O.T20060101

Title: Abnormal glucose tolerance and insulin resistance in polycystic ovary syndrome amongst the Taiwanese population- not correlated with insulin receptor substrate-1 Gly972Arg/Ala513Pro polymorphism.

Journal: BMC medical genetics20060101

Title: Different roles for non-receptor tyrosine kinases in arachidonate release induced by zymosan and Staphylococcus aureus in macrophages.

Journal: Journal of inflammation (London, England)20060101

Title: Cancer and kinases: reports from the front line.

Journal: Genome biology20060101

Title: The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium.

Journal: Breast cancer research : BCR20060101

Title: NMR assignment of the phosphotyrosine binding (PTB) domain of tensin.

Journal: Journal of biomolecular NMR20060101

Title: An active form of Vav1 induces migration of mammary epithelial cells by stimulating secretion of an epidermal growth factor receptor ligand.

Journal: Cell communication and signaling : CCS20060101

Title: Nitric oxide agents impair insulin-mediated signal transduction in rat skeletal muscle.

Journal: BMC biochemistry20060101

Title: The interactome of human EGF/ErbB receptors.

Journal: Molecular systems biology20060101

Title: The proteomes of neurotransmitter receptor complexes form modular networks with distributed functionality underlying plasticity and behaviour.

Journal: Molecular systems biology20060101

Title: Molecular profiling of signalling proteins for effects induced by the anti-cancer compound GSAO with 400 antibodies.

Journal: BMC cancer20060101

Title: Insulin-like growth factor-1 (IGF-1) induces the activation/phosphorylation of Akt kinase and cAMP response element-binding protein (CREB) by activating different signaling pathways in PC12 cells.

Journal: BMC neuroscience20060101

Title: Structure function analysis of SH2D2A isoforms expressed in T cells reveals a crucial role for the proline rich region encoded by SH2D2A exon 7.

Journal: BMC immunology20060101

Title: Phosphoprotein analysis: from proteins to proteomes.

Journal: Proteome science20060101

Title: Beta3 integrin and Src facilitate transforming growth factor-beta mediated induction of epithelial-mesenchymal transition in mammary epithelial cells.

Journal: Breast cancer research : BCR20060101

Title: Redox-mediated bypass of restriction point via skipping of G1pm.

Journal: Theoretical biology & medical modelling20060101

Title: Met-Independent Hepatocyte Growth Factor-mediated regulation of cell adhesion in human prostate cancer cells.

Journal: BMC cancer20060101

Title: Detection of protein tyrosine phosphorylation by open sandwich fluoroimmunoassay.

Journal: Biotechnology progress20060101

Title: Genome-wide gene expression profiling of human mast cells stimulated by IgE or FcepsilonRI-aggregation reveals a complex network of genes involved in inflammatory responses.

Journal: BMC genomics20060101

Title: Design and synthesis of phosphonodifluoromethyl phenylalanine (F2Pmp): a useful phosphotyrosyl mimetic.

Journal: Current topics in medicinal chemistry20060101

Title: Modulation of beta-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family.

Journal: Molecular neurodegeneration20060101

Title: EGF-induced activation of Akt results in mTOR-dependent p70S6 kinase phosphorylation and inhibition of HC11 cell lactogenic differentiation.

Journal: BMC cell biology20060101

Title: Effects of HER2 overexpression on cell signaling networks governing proliferation and migration.

Journal: Molecular systems biology20060101

Title: Towards comprehensive characterization of HER2 overexpression.

Journal: Molecular systems biology20060101

Title: Induction of acid phosphatase activity during germination of maize (Zea mays) seeds.

Journal: Plant physiology and biochemistry : PPB20060101

Title: Tumor suppressor gene methylation in follicular lymphoma: a comprehensive review.

Journal: Molecular cancer20060101

Title: Singlet oxygen inactivates protein tyrosine phosphatase-1B by oxidation of the active site cysteine.

Journal: Biological chemistry20060101

Title: A statistical score for assessing the quality of multiple sequence alignments.

Journal: BMC bioinformatics20060101

Title: Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription.

Journal: Retrovirology20060101

Title: Induction of multiple matrix metalloproteinases in human dermal and synovial fibroblasts by Staphylococcus aureus: implications in the pathogenesis of septic arthritis and other soft tissue infections.

Journal: Arthritis research & therapy20060101

Title: Abnormal insulin-like growth factor 1 signaling in human osteoarthritic subchondral bone osteoblasts.

Journal: Arthritis research & therapy20060101

Title: Greenbottle (Lucilia sericata) larval secretions delivered from a prototype hydrogel wound dressing accelerate the closure of model wounds.

Journal: Biotechnology progress20060101

Title: The expression and action of decay-accelerating factor (CD55) in human malignancies and cancer therapy.

Journal: Cellular oncology : the official journal of the International Society for Cellular Oncology20060101

Title: Xenopus Dab2 is required for embryonic angiogenesis.

Journal: BMC developmental biology20060101

Title: Cooperation between engulfment receptors: the case of ABCA1 and MEGF10.

Journal: PloS one20060101

Title: Tyrosine-specific MAPK phosphatases and the control of ERK signaling in PC12 cells.

Journal: Journal of molecular signaling20060101

Title: Amino terminal tyrosine phosphorylation of human MIXL1.

Journal: Journal of molecular signaling20060101

Title: [Peculiarities of dephosphorylation reaction catalyzed by purified protein tyrosine phosphatase CD45 from thymocytes of intact and exposed to ionising radiation rats].

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 )20060101

Title: [Global gene expression analysis and novel signalling pathways in Hodgkin lymphoma].

Journal: Verhandlungen der Deutschen Gesellschaft fur Pathologie20060101

Title: Role of 14-3-3gamma in FE65-dependent gene transactivation mediated by the amyloid beta-protein precursor cytoplasmic fragment.

Journal: The Journal of biological chemistry20051223

Title: Signals of seminal vesicle autoantigen suppresses bovine serum albumin-induced capacitation in mouse sperm.

Journal: Biochemical and biophysical research communications20051223

Title: SLAM-associated protein as a potential negative regulator in Trk signaling.

Journal: The Journal of biological chemistry20051216

Title: The modular adaptor protein autosomal recessive hypercholesterolemia (ARH) promotes low density lipoprotein receptor clustering into clathrin-coated pits.

Journal: The Journal of biological chemistry20051209

Title: Leptin potentiates ADP-induced [Ca(2+)](i) increase via JAK2 and tyrosine kinases in a megakaryoblast cell line.

Journal: Diabetes research and clinical practice20051201

Title: Muscle contractions, AICAR, and insulin cause phosphorylation of an AMPK-related kinase.

Journal: American journal of physiology. Endocrinology and metabolism20051201

Title: Genistein-induced neuronal differentiation is associated with activation of extracellular signal-regulated kinases and upregulation of p21 and N-cadherin.

Journal: Journal of cellular biochemistry20051201

Title: Highly sensitive peptide-based probes for protein tyrosine phosphatase activity utilizing a fluorogenic mimic of phosphotyrosine.

Journal: Bioorganic & medicinal chemistry letters20051201

Title: The integrin alpha6beta1 modulation of PI3K and Cdc42 activities induces dynamic filopodium formation in human platelets.

Journal: Journal of biomedical science20051201

Title: Intrabacterial proton-dependent CagA transport system in Helicobacter pylori.

Journal: Journal of medical microbiology20051201

Title: Systematic discovery of new recognition peptides mediating protein interaction networks.

Journal: PLoS biology20051201

Title: Secondary structure assignment of mouse SOCS3 by NMR defines the domain boundaries and identifies an unstructured insertion in the SH2 domain.

Journal: The FEBS journal20051201

Title: Cellular prostatic acid phosphatase: a protein tyrosine phosphatase involved in androgen-independent proliferation of prostate cancer.

Journal: Endocrine-related cancer20051201

Title: Helicobacter pylori CagA: a new paradigm for bacterial carcinogenesis.

Journal: Cancer science20051201

Title: Probing the secondary structure of a recombinant neuronal adaptor protein and its phosphotyrosine binding domains.

Journal: Bioscience, biotechnology, and biochemistry20051201

Title: Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor.

Journal: Biochemical and biophysical research communications20051111

Title: Epidermal growth factor induces tyrosine phosphorylation, membrane insertion, and activation of transient receptor potential channel 4.

Journal: The Journal of biological chemistry20051111

Title: MHC class II/CD38/CD9: a lipid-raft-dependent signaling complex in human monocytes.

Journal: Blood20051101

Title: CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy.

Journal: Blood20051101

Title: Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling.

Journal: Blood20051101

Title: EGF receptor activity is essential for adhesion-induced stress fiber formation and cofilin phosphorylation.

Journal: Cellular signalling20051101

Title: Phosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform.

Journal: Molecular and cellular biology20051101

Title: Modeling T cell antigen discrimination based on feedback control of digital ERK responses.

Journal: PLoS biology20051101

Title: The synaptic muscle-specific kinase (MuSK) complex: new partners, new functions.

Journal: BioEssays : news and reviews in molecular, cellular and developmental biology20051101

Title: Helicobacter pylori-stimulated interleukin-8 (IL-8) promotes cell proliferation through transactivation of epidermal growth factor receptor (EGFR) by disintegrin and metalloproteinase (ADAM) activation.

Journal: Digestive diseases and sciences20051101

Title: Expression patterns of purple acid phosphatase genes in Arabidopsis organs and functional analysis of AtPAP23 predominantly transcribed in flower.

Journal: Plant molecular biology20051101

Title: Regulation of the wild-type and Y1235D mutant Met kinase activation.

Journal: Biochemistry20051101

Title: Effects of dexmedetomidine on hippocampal focal adhesion kinase tyrosine phosphorylation in physiologic and ischemic conditions.

Journal: Anesthesiology20051101

Title: Crystal structure of a complex between protein tyrosine phosphatase 1B and the insulin receptor tyrosine kinase.

Journal: Structure (London, England : 1993)20051101

Title: Integrin alpha1beta1 mediates collagen induction of MMP-13 expression in MC615 chondrocytes.

Journal: Biochimica et biophysica acta20051030

Title: Human Tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages.

Journal: The Journal of biological chemistry20051028

Title: Concise approach to novel isothiazolidinone phosphotyrosine mimetics: microwave-assisted addition of bisulfite to activated olefins.

Journal: Organic letters20051027

Title: Structure-based design and discovery of protein tyrosine phosphatase inhibitors incorporating novel isothiazolidinone heterocyclic phosphotyrosine mimetics.

Journal: Journal of medicinal chemistry20051020

Title: Differential response to gefitinib of cells expressing normal EGFR and the mutant EGFRvIII.

Journal: British journal of cancer20051017

Title: Evidence for the involvement of PECAM-1 in a receptor mediated signal-transduction pathway regulating capacitation-associated tyrosine phosphorylation in human spermatozoa.

Journal: Journal of cell science20051015

Title: Insulin receptor substrate is a mediator of phosphoinositide 3-kinase activation in quiescent pancreatic cancer cells.

Journal: Cancer research20051015

Title: Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain.

Journal: Journal of molecular biology20051014

Title: CD40 ligand-dependent tyrosine nitration of prostacyclin synthase in vivo.

Journal: Circulation20051004

Title: Disruption of Sertoli-germ cell adhesion function in the seminiferous epithelium of the rat testis can be limited to adherens junctions without affecting the blood-testis barrier integrity: an in vivo study using an androgen suppression model.

Journal: Journal of cellular physiology20051001

Title: Simultaneous activation of JAK1 and JAK2 confers IL-3 independent growth on Ba/F3 pro-B cells.

Journal: Journal of cellular biochemistry20051001

Title: Grb2 negatively regulates epidermal growth factor-induced phospholipase C-gamma1 activity through the direct interaction with tyrosine-phosphorylated phospholipase C-gamma1.

Journal: Cellular signalling20051001

Title: Tyrosine phosphatases as regulators of skeletal development and metabolism.

Journal: Journal of cellular biochemistry20051001

Title: Vitamin D receptor agonists induce prostatic acid phosphatase to reduce cell growth and HER-2 signaling in LNCaP-derived human prostate cancer cells.

Journal: The Journal of steroid biochemistry and molecular biology20051001

Title: Insulin, glucagon and fatty acid treatment of hepatocytes does not result in phosphorylation or changes in activity of triacylglycerol hydrolase.

Journal: Biochimica et biophysica acta20051001

Title: Phosphotyrosine binding-mediated oligomerization of downstream of tyrosine kinase (Dok)-1 and Dok-2 is involved in CD2-induced Dok phosphorylation.

Journal: Journal of immunology (Baltimore, Md. : 1950)20051001

Title: Hypoxia-induced post-translational changes in red blood cell protein map of newborns.

Journal: Pediatric research20051001

Title: Combined Abl inhibitor therapy for minimizing drug resistance in chronic myeloid leukemia: Src/Abl inhibitors are compatible with imatinib.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20051001

Title: Increased tyrosine phosphorylation of platelet proteins including pp125(FAK) suggests endogenous activation and aggregation in pulmonary hypertension.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis20051001

Title: [Negative regulation of the JAK/STAT: pathway implication in tumorigenesis].

Journal: Bulletin du cancer20051001

Title: Actin cytoskeleton remodelling in the anterior pituitary folliculostellate cell line TtT/GF: participation of the actin-binding protein cortactin.

Journal: Journal of molecular histology20051001

Title: Neuro-apoptogenic and blood platelet targeting toxins in benthic marine cyanobacteria from the Portuguese coast.

Journal: Aquatic toxicology (Amsterdam, Netherlands)20050930

Title: Phase II trial of tamoxifen and goserelin in recurrent epithelial ovarian cancer.

Journal: British journal of cancer20050919

Title: Pleiotrophin stimulates tyrosine phosphorylation of beta-adducin through inactivation of the transmembrane receptor protein tyrosine phosphatase beta/zeta.

Journal: Biochemical and biophysical research communications20050916

Title: Alternative mode of binding to phosphotyrosyl peptides by Src homology-2 domains.

Journal: Biochemistry20050913

Title: Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation. Contributions of Src- and receptor-tyrosine kinases.

Journal: The Journal of biological chemistry20050909

Title: Lessons from nature: On the molecular recognition elements of the phosphoprotein binding-domains.

Journal: Biotechnology and bioengineering20050905

Title: SarCNU-induced G2/M arrest in hepatoma cells is mediated by a p53-independent phosphorylation of cdc-2 at Tyr15.

Journal: Journal of cellular physiology20050901

Title: Docosahexaenoic acid induces apoptosis in proliferating human endothelial cells.

Journal: Journal of cellular physiology20050901

Title: Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.

Journal: Molecular & cellular proteomics : MCP20050901

Title: CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis.

Journal: Human molecular genetics20050901

Title: Sam68 is tyrosine phosphorylated and recruited to signalling in peripheral blood mononuclear cells from HIV infected patients.

Journal: Clinical and experimental immunology20050901

Title: Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin.

Journal: Development (Cambridge, England)20050901

Title: FAS associated phosphatase (FAP-1) blocks apoptosis of astrocytomas through dephosphorylation of FAS.

Journal: Journal of neuro-oncology20050901

Title: Association/dissociation of a channel-kinase complex underlies state-dependent modulation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20050831

Title: Tumor cell pseudopodial protrusions. Localized signaling domains coordinating cytoskeleton remodeling, cell adhesion, glycolysis, RNA translocation, and protein translation.

Journal: The Journal of biological chemistry20050826

Title: Activation of the neuregulin-1/ErbB signaling pathway promotes the proliferation of neoplastic Schwann cells in human malignant peripheral nerve sheath tumors.

Journal: Oncogene20050825

Title: Cooperation between artificial receptors and supramolecular hydrogels for sensing and discriminating phosphate derivatives.

Journal: Journal of the American Chemical Society20050824

Title: Flow activates ERK1/2 and endothelial nitric oxide synthase via a pathway involving PECAM1, SHP2, and Tie2.

Journal: The Journal of biological chemistry20050819

Title: Src-dependent tyrosine phosphorylation at the tips of growth cone filopodia promotes extension.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20050817

Title: Effector-induced Syk-mediated phosphorylation in human erythrocytes.

Journal: Biochimica et biophysica acta20050815

Title: Design and synthesis of 4-(alpha-hydroxymalonyl)phenylalanine as a new phosphotyrosyl mimetic and its use in growth factor receptor bound 2 src-homology 2 (Grb2 SH2) domain-binding peptides.

Journal: Journal of medicinal chemistry20050811

Title: EGF-induced EGF-receptor and MAP kinase phosphorylation in goat cumulus cells during in vitro maturation.

Journal: Molecular reproduction and development20050801

Title: Systematic analysis of the epidermal growth factor receptor by mass spectrometry reveals stimulation-dependent multisite phosphorylation.

Journal: Molecular & cellular proteomics : MCP20050801

Title: 17 beta-estradiol transiently disrupts adherens junctions in endothelial cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20050801

Title: Loss of Zap-70 and low molecular weight phosphotyrosine phosphatase occurs after therapy in a patient with B-chronic lymphocytic leukemia.

Journal: Leukemia20050801

Title: FcepsilonRI cross-linking activates a type II phosphatidylinositol 4-kinase in RBL 2H3 cells.

Journal: Molecular immunology20050801

Title: Activation of the lysosome-associated p61Hck isoform triggers the biogenesis of podosomes.

Journal: Traffic (Copenhagen, Denmark)20050801

Title: Phospho-specific antibodies: more valuable than originally thought.

Journal: American journal of physiology. Renal physiology20050801

Title: Integrin activation by talin.

Journal: Journal of thrombosis and haemostasis : JTH20050801

Title: Okadaic acid induces tyrosine phosphorylation of IkappaBalpha that mediated by PKR pathway in human osteoblastic MG63 cells.

Journal: Molecular and cellular biochemistry20050801

Title: Imaging epidermal growth factor receptor phosphorylation in human colorectal cancer cells and human tissues.

Journal: The Journal of biological chemistry20050729

Title: Mitochondrial Dok-4 recruits Src kinase and regulates NF-kappaB activation in endothelial cells.

Journal: The Journal of biological chemistry20050715

Title: Subconfluent endothelial cells form podosomes downstream of cytokine and RhoGTPase signaling.

Journal: Experimental cell research20050715

Title: PTPN11 mutations play a minor role in isolated congenital heart disease.

Journal: American journal of medical genetics. Part A20050715

Title: Tyrosine phosphorylation of paxillin affects the metastatic potential of human osteosarcoma.

Journal: Oncogene20050714

Title: Phosphorylation of an alpha-synuclein peptide fragment enhances metal binding.

Journal: Journal of the American Chemical Society20050713

Title: Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20050713

Title: Orientations of nematic liquid crystals on surfaces presenting controlled densities of peptides: amplification of protein-peptide binding events.

Journal: Langmuir : the ACS journal of surfaces and colloids20050705

Title: Transmembrane homodimerization of receptor-like protein tyrosine phosphatases.

Journal: FEBS letters20050704

Title: Synthesis of linear and cyclic phosphopeptides as ligands for the N-terminal SH2-domain of protein tyrosine phosphatase SHP-1.

Journal: Journal of peptide science : an official publication of the European Peptide Society20050701

Title: The role of protein-tyrosine phosphatase 1B in integrin signaling.

Journal: The Journal of biological chemistry20050701

Title: Synthesis of a C-terminally biotinylated macrocyclic peptide mimetic exhibiting high Grb2 SH2 domain-binding affinity.

Journal: Bioorganic & medicinal chemistry20050701

Title: Binding of a diphosphorylated-ITAM peptide to spleen tyrosine kinase (Syk) induces distal conformational changes: a hydrogen exchange mass spectrometry study.

Journal: Journal of the American Society for Mass Spectrometry20050701

Title: Atypical regulation of a green lineage-specific B-type cyclin-dependent kinase.

Journal: Plant physiology20050701

Title: Redox-regulated affinity of the third PDZ domain in the phosphotyrosine phosphatase PTP-BL for cysteine-containing target peptides.

Journal: The FEBS journal20050701

Title: Detection and quantification of on-chip phosphorylated peptides by surface plasmon resonance imaging techniques using a phosphate capture molecule.

Journal: Analytical chemistry20050701

Title: [Identification of proteins interacting with adaptor protein Bam32].

Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology20050701

Title: Induction of apoptosis in the lung tissue from rats exposed to cigarette smoke involves p38/JNK MAPK pathway.

Journal: Chemico-biological interactions20050630

Title: Phosphatidylinositol phosphate kinase type Igamma directly associates with and regulates Shp-1 tyrosine phosphatase.

Journal: The Journal of biological chemistry20050624

Title: CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells.

Journal: Oncogene20050623

Title: Inhibitors of protein tyrosine phosphatases: next-generation drugs?

Journal: Angewandte Chemie (International ed. in English)20050620

Title: Analysis of total phosphotyrosine levels in CD34+ cells from CML patients to predict the response to imatinib mesylate treatment.

Journal: Blood20050615

Title: In situ photoactivation of a caged phosphotyrosine peptide derived from focal adhesion kinase temporarily halts lamellar extension of single migrating tumor cells.

Journal: The Journal of biological chemistry20050610

Title: Identification of a NPXY motif in growth factor receptor-bound protein 14 (Grb14) and its interaction with the phosphotyrosine-binding (PTB) domain of IRS-1.

Journal: Biochemistry20050607

Title: Identification of B cell adaptor for PI3-kinase (BCAP) as an Abl interactor 1-regulated substrate of Abl kinases.

Journal: FEBS letters20050606

Title: Phosphorylation of a tyrosine at the N-terminus regulates the surface expression of GIRK5 homomultimers.

Journal: FEBS letters20050606

Title: Knock-down of LAR protein tyrosine phosphatase induces insulin resistance.

Journal: FEBS letters20050606

Title: SOCS-1 inhibits expression of the antiviral proteins 2',5'-OAS and MxA induced by the novel interferon-lambdas IL-28A and IL-29.

Journal: Biochemical and biophysical research communications20050603

Title: Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography.

Journal: Molecular & cellular proteomics : MCP20050601

Title: Hydrogen peroxide and epidermal growth factor activate phosphatidylinositol 3-kinase and increase sodium transport in A6 cell monolayers.

Journal: American journal of physiology. Renal physiology20050601

Title: Genomic organization of the channel catfish CD45 functional gene and CD45 pseudogenes.

Journal: Immunogenetics20050601

Title: Two-stage affinity purification for inducibly phosphorylated membrane proteins.

Journal: Proteomics20050601

Title: A beta4 integrin-like protein co-localises with a phosphotyrosine containing protein in the oomycete Achlya bisexualis: inhibition of tyrosine phosphorylation slows tip growth.

Journal: Fungal genetics and biology : FG & B20050601

Title: Phosphorylation-driven protein-protein interactions: a protein kinase sensing system.

Journal: Journal of the American Chemical Society20050601

Title: Studies of tyrosine phosphorylation and Src family tyrosine kinases in the lens epithelium.

Journal: Investigative ophthalmology & visual science20050601

Title: Association testing of the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes in 7,883 people.

Journal: Diabetes20050601

Title: Capacitation-associated protein tyrosine phosphorylation and membrane fluidity changes are impaired in the spermatozoa of asthenozoospermic patients.

Journal: Reproduction (Cambridge, England)20050601

Title: Altered protein tyrosine phosphorylation in asthmatic bronchial epithelium.

Journal: The European respiratory journal20050601

Title: Protein phosphorylation in signaling--50 years and counting.

Journal: Trends in biochemical sciences20050601

Title: The effect of simvastatin on the proliferation and differentiation of human bone marrow stromal cells.

Journal: Journal of Korean medical science20050601

Title: Frequent KIT and epidermal growth factor receptor overexpressions in undifferentiated-type breast carcinomas with 'stem-cell-like' features.

Journal: Cancer science20050601

Title: [Differential analysis of tyrosine-phosphorylated proteins in human hepatocellular carcinoma cell lines with different metastasis potentials].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology20050601

Title: Inhibitory activity on matrix metalloproteinases and cell-proliferating activity of tissue inhibitor of metalloproteinases-1 (TIMP-1)-contrastive difference between human and bovine TIMP-1s on mouse cell proliferation.

Journal: Growth factors (Chur, Switzerland)20050601

Title: Src-mediated tyrosine phosphorylation of p47phox in hyperoxia-induced activation of NADPH oxidase and generation of reactive oxygen species in lung endothelial cells.

Journal: The Journal of biological chemistry20050527

Title: Src kinase regulation by phosphorylation and dephosphorylation.

Journal: Biochemical and biophysical research communications20050527

Title: Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II.

Journal: Nature20050519

Title: PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia.

Journal: Blood20050515

Title: Autocrine- and paracrine-activated receptor tyrosine kinases in classic Hodgkin lymphoma.

Journal: Blood20050515

Title: Transmembrane CEACAM1 affects integrin-dependent signaling and regulates extracellular matrix protein-specific morphology and migration of endothelial cells.

Journal: Blood20050515

Title: Rapid ubiquitination of Syk following GPVI activation in platelets.

Journal: Blood20050515

Title: c-Abl tyrosine kinase regulates c-fos gene expression via phosphorylating RNA polymerase II.

Journal: Archives of biochemistry and biophysics20050515

Title: Anti-IgM induces up-regulation and tyrosine-phosphorylation of heterogeneous nuclear ribonucleoprotein K proteins (hnRNP K) in a Ramos B cell line.

Journal: Immunology letters20050515

Title: Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteins.

Journal: The Journal of biological chemistry20050513

Title: Extracellular signal-dependent nuclear import of STAT3 is mediated by various importin alphas.

Journal: Biochemical and biophysical research communications20050513

Title: The SH2-domian-containing inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via tyrosine residue 1356 and involves hepatocyte growth factor (HGF)-induced lamellipodium formation, cell scattering and cell spreading.

Journal: Oncogene20050512

Title: Cucurbitacin Q: a selective STAT3 activation inhibitor with potent antitumor activity.

Journal: Oncogene20050505

Title: Impact of SRC homology 2-containing inositol 5'-phosphatase 2 gene polymorphisms detected in a Japanese population on insulin signaling.

Journal: The Journal of clinical endocrinology and metabolism20050501

Title: Changes in tyrosine phosphorylation associated with true capacitation and capacitation-like state in boar spermatozoa.

Journal: Molecular reproduction and development20050501

Title: A new approach for sequencing human IRS1 phosphotyrosine-containing peptides using CapLC-Q-TOF(micro).

Journal: Journal of mass spectrometry : JMS20050501

Title: Expression, purification, and characterization of rat protein tyrosine phosphatase eta catalytic domain.

Journal: Protein expression and purification20050501

Title: Magnesium sulfate effect on erythrocyte membranes of asphyxiated newborns.

Journal: Clinical biochemistry20050501

Title: EphrinB-EphB signalling regulates clathrin-mediated endocytosis through tyrosine phosphorylation of synaptojanin 1.

Journal: Nature cell biology20050501

Title: Insulin-like growth factor-1 controls type 2 T cell-independent B cell response.

Journal: Journal of immunology (Baltimore, Md. : 1950)20050501

Title: Apolipoprotein J (clusterin) activates rodent microglia in vivo and in vitro.

Journal: Journal of neurochemistry20050501

Title: Ephrin tempers two-faced synaptojanin 1.

Journal: Nature cell biology20050501

Title: Localisation of high acid phosphotyrosine phosphatase activity in afferent arterioles and glomeruli of human kidney.

Journal: Journal of molecular histology20050501

Title: Domain-specific function of ShcC docking protein in neuroblastoma cells.

Journal: Oncogene20050428

Title: The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue.

Journal: Oncogene20050428

Title: CTLA-4 is important in maintaining long-term survival of cardiac allografts.

Journal: Transplantation20050427

Title: Somatostatin receptors 2 and 5 are preferentially expressed in proliferating endothelium.

Journal: British journal of cancer20050425

Title: Fyn binding protein, Fyb, interacts with mammalian actin binding protein, mAbp1.

Journal: FEBS letters20050425

Title: C2 can do it, too.

Journal: Cell20050422

Title: The C2 domain of PKCdelta is a phosphotyrosine binding domain.

Journal: Cell20050422

Title: Size-selected (2-10 nm) gold nanoparticles for matrix assisted laser desorption ionization of peptides.

Journal: Journal of the American Chemical Society20050420

Title: Rapid enrichment and analysis of yeast phosphoproteins using affinity chromatography, 2D-PAGE and peptide mass fingerprinting.

Journal: Yeast (Chichester, England)20050415

Title: Unexpected relative aqueous solubilities of a phosphotyrosine analogue and two phosphonate derivatives.

Journal: Journal of the American Chemical Society20050406

Title: Somatostatin-induced activation and up-regulation of N-methyl-D-aspartate receptor function: mediation through calmodulin-dependent protein kinase II, phospholipase C, protein kinase C, and tyrosine kinase in hippocampal noradrenergic nerve endings.

Journal: The Journal of pharmacology and experimental therapeutics20050401

Title: The sulfogalactose moiety of sulfoglycosphingolipids serves as a mimic of tyrosine phosphate in many recognition processes. Prediction and demonstration of Src homology 2 domain/sulfogalactose binding.

Journal: The Journal of biological chemistry20050401

Title: Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells.

Journal: Molecular & cellular proteomics : MCP20050401

Title: Ring-closing metathesis of C-terminal allylglycine residues with an N-terminal beta-vinyl-substituted phosphotyrosyl mimetic as an approach to novel Grb2 SH2 domain-binding macrocycles.

Journal: Chembiochem : a European journal of chemical biology20050401

Title: Characterization of endocytic vesicles using magnetic microbeads coated with signalling ligands.

Journal: Traffic (Copenhagen, Denmark)20050401

Title: Evaluation of macrocyclic Grb2 SH2 domain-binding peptide mimetics prepared by ring-closing metathesis of C-terminal allylglycines with an N-terminal beta-vinyl-substituted phosphotyrosyl mimetic.

Journal: Bioorganic & medicinal chemistry20050401

Title: Using proteomics to identify potential therapeutic targets in platelets.

Journal: Biochemical Society transactions20050401

Title: Nck-independent actin assembly is mediated by two phosphorylated tyrosines within enteropathogenic Escherichia coli Tir.

Journal: Molecular microbiology20050401

Title: PrpZ, a Salmonella enterica serovar Typhi serine/threonine protein phosphatase 2C with dual substrate specificity.

Journal: Microbiology (Reading, England)20050401

Title: Protein tyrosine phosphatases and signalling.

Journal: The Journal of endocrinology20050401

Title: Syndecan-4 is a signaling molecule for stromal cell-derived factor-1 (SDF-1)/ CXCL12.

Journal: The FEBS journal20050401

Title: The amyloid precursor protein and its network of interacting proteins: physiological and pathological implications.

Journal: Brain research. Brain research reviews20050401

Title: Somatostatin: a hormone for the heart?

Journal: Current vascular pharmacology20050401

Title: Matrix metalloproteinase 19 processes the laminin 5 gamma 2 chain and induces epithelial cell migration.

Journal: Cellular and molecular life sciences : CMLS20050401

Title: Solution structure of the Src homology 2 domain from the human feline sarcoma oncogene Fes.

Journal: Journal of biomolecular NMR20050401

Title: Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis.

Journal: Oncogene20050317

Title: Cbl-mediated ubiquitination of alpha5 integrin subunit mediates fibronectin-dependent osteoblast detachment and apoptosis induced by FGFR2 activation.

Journal: Journal of cell science20050315

Title: The p95-100 kDa ligand of the T cell-specific adaptor (TSAd) protein Src-homology-2 (SH2) domain implicated in TSAd nuclear import is p97 Valosin-containing protein (VCP).

Journal: Immunology letters20050315

Title: Phosphorylation of carboxyl-terminal tyrosines modulates the specificity of Sprouty-2 inhibition of different signaling pathways.

Journal: The Journal of biological chemistry20050311

Title: Design and biological evaluation of linear and cyclic phosphopeptide ligands of the N-terminal SH2 domain of protein tyrosine phosphatase SHP-1.

Journal: Journal of medicinal chemistry20050310

Title: Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket.

Journal: The Journal of biological chemistry20050304

Title: Regulation of connexin43-protein binding in astrocytes in response to chemical ischemia/hypoxia.

Journal: The Journal of biological chemistry20050304

Title: Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions.

Journal: The Journal of biological chemistry20050304

Title: Intracellular protein phosphorylation in adherent U937 monocytes mediated by various culture conditions and fibronectin-derived surface ligands.

Journal: Biomaterials20050301

Title: T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells.

Journal: Journal of cellular biochemistry20050301

Title: beta-Phenylethyl isothiocyanate mediated apoptosis: a proteomic investigation of early apoptotic protein changes.

Journal: Proteomics20050301

Title: Zedoariae rhizoma and curcumin inhibits platelet-derived growth factor-induced proliferation of human hepatic myofibroblasts.

Journal: International immunopharmacology20050301

Title: Mutation of chicken anemia virus VP2 differentially affects serine/threonine and tyrosine protein phosphatase activities.

Journal: The Journal of general virology20050301

Title: A nonspecific phosphotyrosine phosphatase inhibitor, bis(maltolato)oxovanadium(IV), improves glucose tolerance and prevents diabetes in Zucker diabetic fatty rats.

Journal: Experimental biology and medicine (Maywood, N.J.)20050301

Title: Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain.

Journal: PLoS medicine20050301

Title: G-protein signaling: back to the future.

Journal: Cellular and molecular life sciences : CMLS20050301

Title: Transient activation of Ras-dependent signalling at the early stages of Herbimycin A induced erythroid differentiation of human K562 cells.

Journal: Experimental oncology20050301

Title: Comparative status of activated ERK1/2 and PARP cleavage in human gliomas.

Journal: Neuropathology : official journal of the Japanese Society of Neuropathology20050301

Title: Site-specific pseudophosphorylation modulates the rate of tau filament dissociation.

Journal: FEBS letters20050227

Title: A newly synthetic chromium complex--chromium(phenylalanine)3 improves insulin responsiveness and reduces whole body glucose tolerance.

Journal: FEBS letters20050227

Title: Angiotensin II induces focal adhesion kinase/paxillin phosphorylation and cell migration in human umbilical vein endothelial cells.

Journal: Biochemical and biophysical research communications20050225

Title: Amlodipine ameliorates myocardial hypertrophy by inhibiting EGFR phosphorylation.

Journal: Biochemical and biophysical research communications20050225

Title: cAMP-dependent tyrosine phosphorylation of subunit I inhibits cytochrome c oxidase activity.

Journal: The Journal of biological chemistry20050218

Title: FLT3/ITD mutation signaling includes suppression of SHP-1.

Journal: The Journal of biological chemistry20050218

Title: Srcasm modulates EGF and Src-kinase signaling in keratinocytes.

Journal: The Journal of biological chemistry20050218

Title: Identification of a molecular recognition role for the activation loop phosphotyrosine of the SRC tyrosine kinase.

Journal: Journal of the American Chemical Society20050216

Title: Hippocampal synaptic modulation by the phosphotyrosine adapter protein ShcC/N-Shc via interaction with the NMDA receptor.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20050216

Title: Regulation of Src kinase activity during Xenopus oocyte maturation.

Journal: Developmental biology20050215

Title: Defective proximal TCR signaling inhibits CD8+ tumor-infiltrating lymphocyte lytic function.

Journal: Journal of immunology (Baltimore, Md. : 1950)20050215

Title: Cross-linking of 4-1BB activates TCR-signaling pathways in CD8+ T lymphocytes.

Journal: Journal of immunology (Baltimore, Md. : 1950)20050215

Title: The SH2 domain: versatile signaling module and pharmaceutical target.

Journal: Biochimica et biophysica acta20050214

Title: Tyrosine kinase inhibitors attenuate Japanese encephalitis virus-induced neurotoxicity.

Journal: Biochemical and biophysical research communications20050211

Title: Tyrosine 769 of the keratinocyte growth factor receptor is required for receptor signaling but not endocytosis.

Journal: Biochemical and biophysical research communications20050211

Title: Comparative analysis of the signaling capabilities of the insulin receptor-related receptor.

Journal: Biochemical and biophysical research communications20050211

Title: Surface plasmon resonance thermodynamic and kinetic analysis as a strategic tool in drug design. Distinct ways for phosphopeptides to plug into Src- and Grb2 SH2 domains.

Journal: Journal of medicinal chemistry20050210

Title: Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics.

Journal: Journal of medicinal chemistry20050210

Title: Probing the communication between the regulatory and catalytic domains of a protein tyrosine kinase, Csk.

Journal: Biochemistry20050208

Title: Peptidomics, current status.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20050205

Title: Photophysics and biological applications of the environment-sensitive fluorophore 6-N,N-dimethylamino-2,3-naphthalimide.

Journal: Journal of the American Chemical Society20050202

Title: Involvement of adenylate cyclase and tyrosine kinase signaling pathways in response of crayfish stretch receptor neuron and satellite glia cell to photodynamic treatment.

Journal: Glia20050201

Title: Theoretical investigations of prostatic acid phosphatase.

Journal: Proteins20050201

Title: Right time, right place: the organization of membrane proximal signaling.

Journal: Seminars in immunology20050201

Title: Connective tissue growth factor CCN2 interacts with and activates the tyrosine kinase receptor TrkA.

Journal: Journal of the American Society of Nephrology : JASN20050201

Title: Application of metal-chelate affinity chromatography to the study of the phosphoproteome.

Journal: Amino acids20050201

Title: The respiratory syncytial virus small hydrophobic protein is phosphorylated via a mitogen-activated protein kinase p38-dependent tyrosine kinase activity during virus infection.

Journal: The Journal of general virology20050201

Title: Molecular and cellular pathogenesis of X-linked lymphoproliferative disease.

Journal: Immunological reviews20050201

Title: Vascular endothelial-cadherin tyrosine phosphorylation in angiogenic and quiescent adult tissues.

Journal: Circulation research20050201

Title: Onychin inhibits proliferation of vascular smooth muscle cells by regulating cell cycle.

Journal: Acta pharmacologica Sinica20050201

Title: Induction of human sperm capacitation and protein tyrosine phosphorylation by endometrial cells and interleukin-6.

Journal: Molecular human reproduction20050201

Title: Phosphodiesterase 4 inhibition decreases MUC5AC expression induced by epidermal growth factor in human airway epithelial cells.

Journal: Thorax20050201

Title: Focal adhesion kinase regulates metastatic adhesion of carcinoma cells within liver sinusoids.

Journal: The American journal of pathology20050201

Title: TINS, target immobilized NMR screening: an efficient and sensitive method for ligand discovery.

Journal: Chemistry & biology20050201

Title: Distinct Grb10 domain requirements for effects on glucose uptake and insulin signaling.

Journal: Molecular and cellular endocrinology20050131

Title: Regulation of upstream binding factor 1 activity by insulin-like growth factor I receptor signaling.

Journal: The Journal of biological chemistry20050128

Title: Prion-associated increases in Src-family kinases.

Journal: The Journal of biological chemistry20050128

Title: T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.

Journal: Science (New York, N.Y.)20050121

Title: NMR dynamics-derived insights into the binding properties of a peptide interacting with an SH2 domain.

Journal: Biochemistry20050118

Title: Characterization of a plant, tyrosine-specific phosphatase of the aspartyl class.

Journal: Biochemistry20050118

Title: Use of phosphoproteomics to study tyrosine kinase activity in capacitating boar sperm. Kinase activity and capacitation.

Journal: Theriogenology20050115

Title: Diazinon alters sperm chromatin structure in mice by phosphorylating nuclear protamines.

Journal: Toxicology and applied pharmacology20050115

Title: The Notch regulator Numb links the Notch and TCR signaling pathways.

Journal: Journal of immunology (Baltimore, Md. : 1950)20050115

Title: The conserved immunoglobulin domain controls the subcellular localization of the homophilic adhesion receptor protein-tyrosine phosphatase mu.

Journal: The Journal of biological chemistry20050114

Title: Novel mechanism of interaction of p85 subunit of phosphatidylinositol 3-kinase and ErbB3 receptor-derived phosphotyrosyl peptides.

Journal: The Journal of biological chemistry20050114

Title: Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinase.

Journal: The Journal of biological chemistry20050114

Title: RGS12 interacts with the SNARE-binding region of the Cav2.2 calcium channel.

Journal: The Journal of biological chemistry20050114

Title: Neurotrophin-dependent tyrosine phosphorylation of Ras guanine-releasing factor 1 and associated neurite outgrowth is dependent on the HIKE domain of TrkA.

Journal: The Journal of biological chemistry20050107

Title: Structural and evolutionary division of phosphotyrosine binding (PTB) domains.

Journal: Journal of molecular biology20050107

Title: Proteomic analysis of phosphotyrosyl proteins in morphine-dependent rat brains.

Journal: Brain research. Molecular brain research20050105

Title: Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors.

Journal: The Journal of clinical investigation20050103

Title: Nongenomic effects of 17beta-estradiol in human platelets: potentiation of thrombin-induced aggregation through estrogen receptor beta and Src kinase.

Journal: Blood20050101

Title: TNFalpha-induced insulin resistance in adipocytes as a membrane microdomain disorder: involvement of ganglioside GM3.

Journal: Glycobiology20050101

Title: Tumor suppressor function of Bruton tyrosine kinase is independent of its catalytic activity.

Journal: Blood20050101

Title: Identification of a novel activating mutation (Y842C) within the activation loop of FLT3 in patients with acute myeloid leukemia (AML).

Journal: Blood20050101

Title: Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412.

Journal: Blood20050101

Title: Bombesin and angiotensin II rapidly stimulate Src phosphorylation at Tyr-418 in fibroblasts and intestinal epithelial cells through a PP2-insensitive pathway.

Journal: Cellular signalling20050101

Title: The protein kinase C inhibitor Go6976 [12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole] potentiates agonist-induced mitogen-activated protein kinase activation through tyrosine phosphorylation of the epidermal growth factor receptor.

Journal: Molecular pharmacology20050101

Title: Listeria monocytogenes produces a pro-invasive factor that signals via ErbB2/ErbB3 heterodimers.

Journal: Journal of cancer research and clinical oncology20050101

Title: Automated immobilized metal affinity chromatography/nano-liquid chromatography/electrospray ionization mass spectrometry platform for profiling protein phosphorylation sites.

Journal: Rapid communications in mass spectrometry : RCM20050101

Title: Measurement of protein tyrosine phosphorylation in cell adhesion.

Journal: Methods in molecular biology (Clifton, N.J.)20050101

Title: Risk of type 1 diabetes in childhood and maternal age at delivery, interaction with ACP1 and sex.

Journal: Diabetes/metabolism research and reviews20050101

Title: Regulation of receptor protein-tyrosine phosphatase dimerization.

Journal: Methods (San Diego, Calif.)20050101

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

Journal: Nature biotechnology20050101

Title: Peptide-specific intercellular transfer of MHC class II to CD4+ T cells directly from the immunological synapse upon cellular dissociation.

Journal: Journal of immunology (Baltimore, Md. : 1950)20050101

Title: Fully automated synthesis of (phospho)peptide arrays in microtiter plate wells provides efficient access to protein tyrosine kinase characterization.

Journal: BMC immunology20050101

Title: Inflammation and carnitine in hemodialysis patients.

Journal: Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation20050101

Title: Phosphoprotein profiling of erythropoietin receptor- dependent pathways using different proteomic strategies.

Journal: Proteomics20050101

Title: Novel hepatocyte growth factor (HGF) binding domains on fibronectin and vitronectin coordinate a distinct and amplified Met-integrin induced signalling pathway in endothelial cells.

Journal: BMC cell biology20050101

Title: Phosphoproteomic analysis using immobilized metal ion affinity chromatography on the basis of cellulose powder.

Journal: Proteomics20050101

Title: Tyrosine phosphorylation of myosin heavy chain during skeletal muscle differentiation: an integrated bioinformatics approach.

Journal: Theoretical biology & medical modelling20050101

Title: Local delivery of soluble interleukin-6 receptors to improve the outcome of alpha-toxin producing Staphylococcus aureus infection in mice.

Journal: Immunobiology20050101

Title: Action of fenretinide (4-HPR) on ovarian cancer and endothelial cells.

Journal: Anticancer research20050101

Title: A novel EB-1/AIDA-1 isoform, AIDA-1c, interacts with the Cajal body protein coilin.

Journal: BMC cell biology20050101

Title: Hyperglycemia potentiates H(2)O(2) production in adipocytes and enhances insulin signal transduction: potential role for oxidative inhibition of thiol-sensitive protein-tyrosine phosphatases.

Journal: Antioxidants & redox signaling20050101

Title: Anchorage-dependent cell growth: tyrosine kinases and phosphatases meet redox regulation.

Journal: Antioxidants & redox signaling20050101

Title: The integrins of the urochordate Ciona intestinalis provide novel insights into the molecular evolution of the vertebrate integrin family.

Journal: BMC evolutionary biology20050101

Title: Possible active origin of replication in the double stranded extended form of the left terminus of LuIII and its implication on the replication model of the parvovirus.

Journal: Virology journal20050101

Title: 14-3-3 protein signaling in development and growth factor responses.

Journal: Current topics in developmental biology20050101

Title: The proacrosin binding protein, sp32, is tyrosine phosphorylated during capacitation of pig sperm.

Journal: Journal of andrology20050101

Title: Regulation of mouse hepatic genes in response to diet induced obesity, insulin resistance and fasting induced weight reduction.

Journal: Nutrition & metabolism20050101

Title: H2O2-induced phosphorylation of ERK1/2 and PKB requires tyrosine kinase activity of insulin receptor and c-Src.

Journal: Antioxidants & redox signaling20050101

Title: Role of insulin-induced reactive oxygen species in the insulin signaling pathway.

Journal: Antioxidants & redox signaling20050101

Title: Global gene expression analysis in time series following N-acetyl L-cysteine induced epithelial differentiation of human normal and cancer cells in vitro.

Journal: BMC cancer20050101

Title: Relative quantification of erythropoietin receptor-dependent phosphoproteins using in-gel 18O-labeling and tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM20050101

Title: Early-stage folding in proteins (in silico) sequence-to-structure relation.

Journal: Journal of biomedicine & biotechnology20050101

Title: Spinal cord NR1 serine phosphorylation and NR2B subunit suppression following peripheral inflammation.

Journal: Molecular pain20050101

Title: Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi.

Journal: BMC genomics20050101

Title: Phosphoproteomics: new insights into cellular signaling.

Journal: Genome biology20050101

Title: Differential responses to doxorubicin-induced phosphorylation and activation of Akt in human breast cancer cells.

Journal: Breast cancer research : BCR20050101

Title: Construction and validation of a Bovine Innate Immune Microarray.

Journal: BMC genomics20050101

Title: Activation of focal adhesion kinase enhances the adhesion and invasion of pancreatic cancer cells via extracellular signal-regulated kinase-1/2 signaling pathway activation.

Journal: Molecular cancer20050101

Title: The novel protein KBP regulates mitochondria localization by interaction with a kinesin-like protein.

Journal: BMC cell biology20050101

Title: Mapping and characterization of the amplicon near APOA2 in 1q23 in human sarcomas by FISH and array CGH.

Journal: Molecular cancer20050101

Title: E3 ubiquitin ligases and their control of T cell autoreactivity.

Journal: Arthritis research & therapy20050101

Title: Peroxynitrite-dependent upregulation of SRC kinases in red blood cells: strategies to study the activation mechanisms.

Journal: Methods in enzymology20050101

Title: FGF receptor phosphotyrosine 766 is a target for Grb14 to inhibit MDA-MB-231 human breast cancer cell signaling.

Journal: Anticancer research20050101

Title: Protein kinase activity is associated with CD63 in melanoma cells.

Journal: Journal of translational medicine20050101

Title: A neural strategy for the inference of SH3 domain-peptide interaction specificity.

Journal: BMC bioinformatics20050101

Title: C/EBPbeta-2 confers EGF-independent growth and disrupts the normal acinar architecture of human mammary epithelial cells.

Journal: Molecular cancer20050101

Title: Phosphate isosteres in medicinal chemistry.

Journal: Current medicinal chemistry20050101

Title: A new tyrosine phosphorylation mechanism involved in signal transduction in Bacillus subtilis.

Journal: Journal of molecular microbiology and biotechnology20050101

Title: Protein-tyrosine phosphorylation in Bacillus subtilis.

Journal: Journal of molecular microbiology and biotechnology20050101

Title: Interaction between the Yersinia tyrosine phosphatase YopH and its macrophage substrate, Fyn-binding protein, Fyb.

Journal: Journal of molecular microbiology and biotechnology20050101

Title: Inhibition of CCN6 (WISP3) expression promotes neoplastic progression and enhances the effects of insulin-like growth factor-1 on breast epithelial cells.

Journal: Breast cancer research : BCR20050101

Title: Tyrosine phosphorylation of Rab proteins.

Journal: Methods in enzymology20050101

Title: During muscle ageing the activation of the mitogenic signalling is not sufficient to guarantee cellular duplication.

Journal: The Italian journal of biochemistry20050101

Title: Phosphotyrosine interactome of the ErbB-receptor kinase family.

Journal: Molecular systems biology20050101

Title: A comprehensive pathway map of epidermal growth factor receptor signaling.

Journal: Molecular systems biology20050101

Title: Ribonucleopeptides recognize the phosphotyrosine residue.

Journal: Nucleic acids symposium series (2004)20050101

Title: Ubiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitment.

Journal: The Journal of biological chemistry20041231

Title: Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen.

Journal: The Journal of biological chemistry20041224

Title: Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of toll-like receptor signaling.

Journal: The Journal of biological chemistry20041224

Title: Phospholipase D1 regulates high-affinity IgE receptor-induced mast cell degranulation.

Journal: Blood20041215

Title: Distinctive activation mechanisms and functions for protein kinase Cdelta.

Journal: The Biochemical journal20041215

Title: dPak is required for integrity of the leading edge cytoskeleton during Drosophila dorsal closure but does not signal through the JNK cascade.

Journal: Developmental biology20041215

Title: Retinoids arrest breast cancer cell proliferation: retinoic acid selectively reduces the duration of receptor tyrosine kinase signaling.

Journal: Experimental cell research20041210

Title: A nonhydrolyzable analogue of phosphotyrosine, and related aryloxymethano- and aryloxyethano-phosphonic acids as motifs for inhibition of phosphatases.

Journal: Bioorganic & medicinal chemistry letters20041206

Title: Implication of cAMP during porcine sperm capacitation and protein tyrosine phosphorylation.

Journal: Molecular reproduction and development20041201

Title: A cyclic adenosine 3',5'-monophosphate-induced tyrosine phosphorylation of Syk protein tyrosine kinase in the flagella of boar spermatozoa.

Journal: Molecular reproduction and development20041201

Title: Immunohistochemical analysis of tyrosine phosphorylation and AP-1 transcription factors c-Jun, Jun D, and Fos family during early ovarian follicle development in the mouse.

Journal: Applied immunohistochemistry & molecular morphology : AIMM20041201

Title: Correlation between tyrosine phosphorylation intensity of a 107 kDa protein band and A23187-induced acrosome reaction in human spermatozoa.

Journal: Andrologia20041201

Title: IREM-1 is a novel inhibitory receptor expressed by myeloid cells.

Journal: European journal of immunology20041201

Title: Role of ErbB2 in Corneal Epithelial Wound Healing.

Journal: Investigative ophthalmology & visual science20041201

Title: Nitric oxide block of outward-rectifying K+ channels indicates direct control by protein nitrosylation in guard cells.

Journal: Plant physiology20041201

Title: Mapping netrin receptor binding reveals domains of Unc5 regulating its tyrosine phosphorylation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20041201

Title: Mechanisms of resistance to Erbitux (anti-epidermal growth factor receptor) combination therapy in pancreatic adenocarcinoma cells.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract20041201

Title: Thrombopoietin regulates proliferation, apoptosis, secretory activity and intracellular messengers in porcine ovarian follicular cells: involvement of protein kinase A.

Journal: The Journal of endocrinology20041201

Title: The phosphotyrosine phosphatase eta mediates somatostatin inhibition of glioma proliferation via the dephosphorylation of ERK1/2.

Journal: Annals of the New York Academy of Sciences20041201

Title: Activation of signal transducer and activator of transcription 5 (STAT5) in splenocyte proliferation of asthma mice induced by ovalbumin.

Journal: Cellular & molecular immunology20041201

Title: Characterization of Lck-binding elements in the herpesviral regulatory Tip protein.

Journal: Biochemistry20041130

Title: Src protein-tyrosine kinase structure and regulation.

Journal: Biochemical and biophysical research communications20041126

Title: TMF/ARA160 is a BC-box-containing protein that mediates the degradation of Stat3.

Journal: Oncogene20041125

Title: Mechanisms involved in the blood-brain barrier increased permeability induced by Phoneutria nigriventer spider venom in rats.

Journal: Brain research20041119

Title: Tyrosine phosphorylation of caveolin-2 at residue 27: differences in the spatial and temporal behavior of phospho-Cav-2 (pY19 and pY27).

Journal: Biochemistry20041102

Title: IL-6-induced survival of colorectal carcinoma cells is inhibited by butyrate through down-regulation of the IL-6 receptor.

Journal: Carcinogenesis20041101

Title: Deletion of the pleckstrin and phosphotyrosine binding domains of insulin receptor substrate-2 does not impair its ability to regulate cell proliferation in myeloid cells.

Journal: Endocrinology20041101

Title: A prototype antibody microarray platform to monitor changes in protein tyrosine phosphorylation.

Journal: Molecular & cellular proteomics : MCP20041101

Title: Rapid detection of phosphotyrosine proteins by flow cytometric analysis in Bcr-Abl-positive cells.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20041101

Title: Modulation of Erbb2 signaling during development: a threshold level of Erbb2 signaling is required for development.

Journal: Development (Cambridge, England)20041101

Title: From modulator to mediator: rapid effects of BDNF on ion channels.

Journal: BioEssays : news and reviews in molecular, cellular and developmental biology20041101

Title: Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes.

Journal: Diabetes20041101

Title: Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study.

Journal: Diabetes20041101

Title: Expression of FGF-2 alters focal adhesion dynamics in migration-restricted MDA-MB-231 breast cancer cells.

Journal: Breast cancer research and treatment20041101

Title: Development of a polyvalent assay system for lead identification.

Journal: Bioorganic & medicinal chemistry letters20041018

Title: Structure and regulation of Src family kinases.

Journal: Oncogene20041018

Title: Inhibition of wild-type and mutant Bcr-Abl by AP23464, a potent ATP-based oncogenic protein kinase inhibitor: implications for CML.

Journal: Blood20041015

Title: Loss of SHIP and CIS recruitment to the granulocyte colony-stimulating factor receptor contribute to hyperproliferative responses in severe congenital neutropenia/acute myelogenous leukemia.

Journal: Journal of immunology (Baltimore, Md. : 1950)20041015

Title: The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway.

Journal: Oncogene20041014

Title: Alpha2-chimaerin, cyclin-dependent Kinase 5/p35, and its target collapsin response mediator protein-2 are essential components in semaphorin 3A-induced growth-cone collapse.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20041013

Title: X-ray crystal structure of the hypothetical phosphotyrosine phosphatase MDP-1 of the haloacid dehalogenase superfamily.

Journal: Biochemistry20041012

Title: Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes.

Journal: American journal of respiratory cell and molecular biology20041001

Title: Characterization of two distinct dual specificity phosphatases encoded in alternative open reading frames of a single gene located on human chromosome 10q22.2.

Journal: The Journal of biological chemistry20041001

Title: Alternative activation of STAT1 and STAT3 in response to interferon-gamma.

Journal: The Journal of biological chemistry20041001

Title: SRC mediates a switch from microtubule- to actin-based motility of vaccinia virus.

Journal: Science (New York, N.Y.)20041001

Title: The efficiency of mispaired ligations by lambda integrase is extremely sensitive to context.

Journal: Journal of molecular biology20041001

Title: Inhibition of serum-stimulated mitogen activated protein kinase by 1alpha,25(OH)2-vitamin D3 in MCF-7 breast cancer cells.

Journal: Journal of cellular biochemistry20041001

Title: Enhanced expression of adaptor molecule p46 Shc in nuclei of hepatocellular carcinoma cells: study of LEC rats.

Journal: International journal of oncology20041001

Title: Insulin resistance in thermally-injured rats is associated with post-receptor alterations in skeletal muscle, liver and adipose tissue.

Journal: International journal of molecular medicine20041001

Title: Enhancement of insulin signaling through inhibition of tissue lipid accumulation by activation of peroxisome proliferator-activated receptor (PPAR) alpha in obese mice.

Journal: Medical science monitor : international medical journal of experimental and clinical research20041001

Title: Cytoplasmic tail adaptors of Alzheimer's amyloid-beta protein precursor.

Journal: Molecular neurobiology20041001

Title: Increased expression of focal adhesion kinase in thyroid cancer: immunohistochemical study.

Journal: Journal of Korean medical science20041001

Title: An improved method for utilization of peptide substrates for antibody characterization and enzymatic assays.

Journal: Journal of immunological methods20041001

Title: Inhibitors for proteins endowed with catalytic and non-catalytic activity which recognize pTyr.

Journal: Current medicinal chemistry20041001

Title: Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.

Journal: The Journal of biological chemistry20040924

Title: CAS promotes invasiveness of Src-transformed cells.

Journal: Oncogene20040923

Title: Hypotonicity-induced exocytosis of the skate anion exchanger skAE1: role of lipid raft regions.

Journal: The Journal of biological chemistry20040917

Title: Mild impairment of motor nerve repair in mice lacking PTP-BL tyrosine phosphatase activity.

Journal: Physiological genomics20040916

Title: Proteomic analysis of phosphotyrosyl proteins in the rat brain: effect of butorphanol dependence.

Journal: Journal of neuroscience research20040915

Title: Long-lasting rescue of age-associated deficits in cognition and the CNS cholinergic phenotype by a partial agonist peptidomimetic ligand of TrkA.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20040915

Title: Recombinant humanised anti-HER2/neu antibody (Herceptin) induces cellular death of glioblastomas.

Journal: British journal of cancer20040913

Title: Sustained antiproliferative mechanisms by RB24, a targeted precursor of multiple inhibitors of epidermal growth factor receptor and a DNA alkylating agent in the A431 epidermal carcinoma of the vulva cell line.

Journal: British journal of cancer20040913

Title: Tyrosine phosphorylation, thiol status, and protein tyrosine phosphatase in rat epididymal spermatozoa.

Journal: Biology of reproduction20040901

Title: IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells.

Journal: The Journal of pharmacology and experimental therapeutics20040901

Title: Characterization of protein tyrosine phosphatase activity in rat liver microsomes: suppressive effect of endogenous regucalcin in transgenic rats.

Journal: International journal of molecular medicine20040901

Title: Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics.

Journal: Nature biotechnology20040901

Title: Solution structure of the human Grb14-SH2 domain and comparison with the structures of the human Grb7-SH2/erbB2 peptide complex and human Grb10-SH2 domain.

Journal: Protein science : a publication of the Protein Society20040901

Title: Control of vesicle fusion by a tyrosine phosphatase.

Journal: Nature cell biology20040901

Title: The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanisms.

Journal: PLoS biology20040901

Title: Water-molecule network and active-site flexibility of apo protein tyrosine phosphatase 1B.

Journal: Acta crystallographica. Section D, Biological crystallography20040901

Title: Phosphoproteomics finds its timing.

Journal: Nature biotechnology20040901

Title: Apoptotic cell death influences the signaling activity of the amyloid precursor protein through ShcA and Grb2 adaptor proteins in neuroblastoma SH-SY5Y cells.

Journal: Journal of neurochemistry20040901

Title: The identification of Dictyostelium phosphoproteins altered in response to the activation of RasG.

Journal: Proteomics20040901

Title: Reduced plasma membrane Ca2+-ATPase function in platelets from patients with non-insulin-dependent diabetes mellitus.

Journal: Haematologica20040901

Title: The dual-function disabled-1 PTB domain exhibits site independence in binding phosphoinositide and peptide ligands.

Journal: Biochemistry20040831

Title: Mouse embryonic fibroblasts derived from Odin deficient mice display a hyperproliiferative phenotype.

Journal: DNA research : an international journal for rapid publication of reports on genes and genomes20040831

Title: Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiation.

Journal: The Journal of biological chemistry20040827

Title: Imaging phosphorylation dynamics of the epidermal growth factor receptor.

Journal: The Journal of biological chemistry20040827

Title: Sustained stimulation of platelet thrombin receptor is associated with tyrosine dephosphorylation of a novel p67 peptide in a manner regulated by extracellular calcium.

Journal: Biochimica et biophysica acta20040823

Title: The in vivo tyrosine phosphorylation level of yeast immunophilin Fpr3 is influenced by the LMW-PTP Ltp1.

Journal: Biochemical and biophysical research communications20040820

Title: MUC1 tyrosine phosphorylation activates the extracellular signal-regulated kinase.

Journal: Biochemical and biophysical research communications20040820

Title: LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation.

Journal: The EMBO journal20040818

Title: Dual blockade of EGFR and ERK1/2 phosphorylation potentiates growth inhibition of breast cancer cells.

Journal: British journal of cancer20040816

Title: Upregulation of the transcript level of GTPase activating protein KIAA0603 in T cells from patients with atopic dermatitis.

Journal: FEBS letters20040813

Title: Molecular cloning and characterization of a novel dual-specificity phosphatase 23 gene from human fetal brain.

Journal: The international journal of biochemistry & cell biology20040801

Title: Prosaposin: a new player in cell death prevention of U937 monocytic cells.

Journal: Experimental cell research20040801

Title: Complexes of gamma-tubulin with nonreceptor protein tyrosine kinases Src and Fyn in differentiating P19 embryonal carcinoma cells.

Journal: Experimental cell research20040801

Title: Analysis of Chlamydia caviae entry sites and involvement of Cdc42 and Rac activity.

Journal: Journal of cell science20040801

Title: Role of EGFR transactivation in preventing apoptosis in Pseudomonas aeruginosa-infected human corneal epithelial cells.

Journal: Investigative ophthalmology & visual science20040801

Title: EspFU is a translocated EHEC effector that interacts with Tir and N-WASP and promotes Nck-independent actin assembly.

Journal: Developmental cell20040801

Title: Finding functional sites in structural genomics proteins.

Journal: Structure (London, England : 1993)20040801

Title: Characterization of dynamic and steady-state protein phosphorylation using a fluorescent phosphoprotein gel stain and mass spectrometry.

Journal: Electrophoresis20040801

Title: IFN-alpha5 mediates stronger Tyk2-stat-dependent activation and higher expression of 2',5'-oligoadenylate synthetase than IFN-alpha2 in liver cells.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research20040801

Title: Development of a quantitative, high-throughput cell-based enzyme-linked immunosorbent assay for detection of colony-stimulating factor-1 receptor tyrosine kinase inhibitors.

Journal: Journal of biochemical and biophysical methods20040730

Title: Tracing kinetic intermediates during ligand binding.

Journal: Journal of the American Chemical Society20040728

Title: Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation.

Journal: The Journal of biological chemistry20040716

Title: Tyrosine phosphorylation activates surface chaperones facilitating sperm-zona recognition.

Journal: Journal of cell science20040715

Title: Probing the transition-state structure of dual-specificity protein phosphatases using a physiological substrate mimic.

Journal: Biochemistry20040713

Title: The expression of the phosphotyrosine phosphatase DEP-1/PTPeta dictates the responsivity of glioma cells to somatostatin inhibition of cell proliferation.

Journal: The Journal of biological chemistry20040709

Title: Identification of the linker-SH2 domain of STAT as the origin of the SH2 domain using two-dimensional structural alignment.

Journal: Molecular & cellular proteomics : MCP20040701

Title: Cross-linking of MHC class I molecules on human NK cells inhibits NK cell function, segregates MHC I from the NK cell synapse, and induces intracellular phosphotyrosines.

Journal: Journal of leukocyte biology20040701

Title: Early molecular events in the assembly of the focal adhesion-stress fiber complex during fibroblast spreading.

Journal: Cell motility and the cytoskeleton20040701

Title: A method for simultaneous alignment of multiple protein structures.

Journal: Proteins20040701

Title: Epidermal growth factor stimulation of RPE cell survival: contribution of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways.

Journal: Experimental eye research20040701

Title: A high-throughput fluorescence polarization assay for signal transducer and activator of transcription 3.

Journal: Analytical biochemistry20040701

Title: TFIIH contains a PH domain involved in DNA nucleotide excision repair.

Journal: Nature structural & molecular biology20040701

Title: Tyrosine phosphorylation of calponins. Inhibition of the interaction with F-actin.

Journal: European journal of biochemistry20040701

Title: Changes in structural dynamics of the Grb2 adaptor protein upon binding of phosphotyrosine ligand to its SH2 domain.

Journal: Biochimica et biophysica acta20040701

Title: Identification of non-phosphate-containing small molecular weight inhibitors of the tyrosine kinase p56 Lck SH2 domain via in silico screening against the pY + 3 binding site.

Journal: Journal of medicinal chemistry20040701

Title: Singlet oxygen-induced attenuation of growth factor signaling: possible role of ceramides.

Journal: Free radical research20040701

Title: Development of l-3-aminotyrosine suitably protected for the synthesis of a novel nonphosphorylated hexapeptide with low-nanomolar Grb2-SH2 domain-binding affinity.

Journal: Bioorganic & medicinal chemistry letters20040621

Title: Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors.

Journal: Blood20040615

Title: Human marrow stromal cells activate monocytes to secrete osteopontin, which down-regulates Notch1 gene expression in CD34+ cells.

Journal: Blood20040615

Title: p120 Ras GTPase-activating protein associates with fibroblast growth factor receptors in Drosophila.

Journal: The Biochemical journal20040615

Title: The ErbB signaling network is coordinately expressed and activated in the mouse prostate.

Journal: The Prostate20040615

Title: A proteomic approach to identify phosphoproteins encoded by cDNA libraries.

Journal: Analytical biochemistry20040615

Title: Gene expression profiles in an hepatitis B virus transfected hepatoblastoma cell line and differentially regulated gene expression by interferon-alpha.

Journal: World journal of gastroenterology20040615

Title: Selective tyrosine hyperphosphorylation of cytoskeletal and stress proteins in primary human breast cancers: implications for adjuvant use of kinase-inhibitory drugs.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20040615

Title: Growth factor receptor-bound protein 2 interaction with the tyrosine-phosphorylated tail of amyloid beta precursor protein is mediated by its Src homology 2 domain.

Journal: The Journal of biological chemistry20040611

Title: Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action.

Journal: The Journal of biological chemistry20040604

Title: Actin depolymerization-induced tyrosine phosphorylation of cortactin: the role of Fer kinase.

Journal: The Biochemical journal20040601

Title: Isolation and partial characterisation of acid phosphatase isozymes from dormant oilseed of Corylus avellana L.

Journal: Planta20040601

Title: Activation and inhibition of cyclin-dependent kinase-2 by phosphorylation; a molecular dynamics study reveals the functional importance of the glycine-rich loop.

Journal: Protein science : a publication of the Protein Society20040601

Title: Exacerbated graft-versus-host disease in Pirb-/- mice.

Journal: Nature immunology20040601

Title: Ca(2+)-sensitive tyrosine kinase Pyk2/CAK beta-dependent signaling is essential for G-protein-coupled receptor agonist-induced hypertrophy.

Journal: Journal of molecular and cellular cardiology20040601

Title: Cytoplasmic p120ctn regulates the invasive phenotypes of E-cadherin-deficient breast cancer.

Journal: The American journal of pathology20040601

Title: Regulation of haematopoiesis by growth factors - emerging insights and therapies.

Journal: Expert opinion on biological therapy20040601

Title: Growth hormone (GH) receptors in prostate cancer: gene expression in human tissues and cell lines and characterization, GH signaling and androgen receptor regulation in LNCaP cells.

Journal: Molecular and cellular endocrinology20040531

Title: Temporal dissection of beta1-integrin signaling indicates a role for p130Cas-Crk in filopodia formation.

Journal: The Journal of biological chemistry20040528

Title: The low density lipoprotein receptor-related protein is a motogenic receptor for plasminogen activator inhibitor-1.

Journal: The Journal of biological chemistry20040521

Title: The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration.

Journal: The Journal of biological chemistry20040521

Title: The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65/amyloid precursor protein nuclear signaling.

Journal: The Journal of biological chemistry20040521

Title: Tyrosine phosphorylated Disabled 1 recruits Crk family adapter proteins.

Journal: Biochemical and biophysical research communications20040521

Title: SRC-dependent outside-in signalling is a key step in the process of autoregulation of beta2 integrins in polymorphonuclear cells.

Journal: The Biochemical journal20040515

Title: A novel 110 kDa form of myosin XVIIIA (MysPDZ) is tyrosine-phosphorylated after colony-stimulating factor-1 receptor signalling.

Journal: The Biochemical journal20040515

Title: The aryl hydrocarbon receptor (AhR) tyrosine 9, a residue that is essential for AhR DNA binding activity, is not a phosphoresidue but augments AhR phosphorylation.

Journal: The Journal of biological chemistry20040514

Title: Critical role for hematopoietic cell kinase (Hck)-mediated phosphorylation of Gab1 and Gab2 docking proteins in interleukin 6-induced proliferation and survival of multiple myeloma cells.

Journal: The Journal of biological chemistry20040514

Title: Primary and essential role of the adaptor protein APS for recruitment of both c-Cbl and its associated protein CAP in insulin signaling.

Journal: The Journal of biological chemistry20040514

Title: Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells.

Journal: Circulation research20040514

Title: SH3P2 in complex with Cbl and Src.

Journal: FEBS letters20040507

Title: Electrochemistry/mass spectrometry (EC/MS)--a new tool to study drug metabolism and reaction mechanisms.

Journal: Angewandte Chemie (International ed. in English)20040503

Title: Regulation and localization of CAS substrate domain tyrosine phosphorylation.

Journal: Cellular signalling20040501

Title: Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.

Journal: The Biochemical journal20040501

Title: Characterization of the interactions of estrogen receptor and MNAR in the activation of cSrc.

Journal: Molecular endocrinology (Baltimore, Md.)20040501

Title: Alterations of cell signaling pathways in pancreatic cancer.

Journal: Frontiers in bioscience : a journal and virtual library20040501

Title: Phosphotyrosine phosphatases acting on band 3 in human erythrocytes of different age: PTP1B processing during cell ageing.

Journal: Bioelectrochemistry (Amsterdam, Netherlands)20040501

Title: Identification of p46 Shc expressed in the nuclei of hepatocytes with high proliferating activity: Study of regenerating rat liver.

Journal: International journal of molecular medicine20040501

Title: Tyrosine phosphorylation of NOS3 in a breast cancer cell line and Src-transformed cells.

Journal: Oncology reports20040501

Title: A quantum mechanical study on phosphotyrosyl peptide binding to the SH2 domain of p56lck tyrosine kinase with insights into the biochemistry of intracellular signal transduction events.

Journal: Biophysical chemistry20040501

Title: MERTK arginine-844-cysteine in a patient with severe rod-cone dystrophy: loss of mutant protein function in transfected cells.

Journal: Investigative ophthalmology & visual science20040501

Title: Angiotensin II stimulates cAMP production and protein tyrosine phosphorylation in mouse spermatozoa.

Journal: Reproduction (Cambridge, England)20040501

Title: Focal adhesion and actin dynamics: a place where kinases and proteases meet to promote invasion.

Journal: Trends in cell biology20040501

Title: Increasing neutrophil F-actin corrects CD11b exposure in Type 2 diabetes.

Journal: European journal of clinical investigation20040501

Title: American Chemical Society--227th annual meeting. Diabetes. 28 March - 1 April 2004, Anaheim, CA, USA.

Journal: IDrugs : the investigational drugs journal20040501

Title: Dietary branched-chain amino acids suppress the expression of pancreatic amylase mRNA in rats.

Journal: Bioscience, biotechnology, and biochemistry20040501

Title: Proteomic approach to the identification of voltage-dependent anion channel protein isoforms in guinea pig brain synaptosomes.

Journal: Proteomics20040501

Title: Pleckstrin homology and phosphotyrosine-binding domain-dependent membrane association and tyrosine phosphorylation of Dok-4, an inhibitory adapter molecule expressed in epithelial cells.

Journal: The Journal of biological chemistry20040430

Title: Structural requirements for signal transducer and activator of transcription 3 binding to phosphotyrosine ligands containing the YXXQ motif.

Journal: The Journal of biological chemistry20040430

Title: A single residue modulates tyrosine dephosphorylation, oligomerization, and nuclear accumulation of stat transcription factors.

Journal: The Journal of biological chemistry20040430

Title: Alternative splicing modulates Disabled-1 (Dab1) function in the developing chick retina.

Journal: The EMBO journal20040421

Title: Adhesion-dependent regulation of p190RhoGAP in the developing brain by the Abl-related gene tyrosine kinase.

Journal: Current biology : CB20040420

Title: Phosphotyrosyl peptides and analogues as substrates and inhibitors of purple acid phosphatases.

Journal: Archives of biochemistry and biophysics20040415

Title: Tyrosine phosphorylation of the Janus kinase 2 activation loop is essential for a high-activity catalytic state but dispensable for a basal catalytic state.

Journal: Biochemistry20040413

Title: Catalytic inactivation of protein tyrosine phosphatase CD45 and protein tyrosine phosphatase 1B by polyaromatic quinones.

Journal: Biochemistry20040413

Title: Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia.

Journal: The Journal of biological chemistry20040409

Title: Identification of RET autophosphorylation sites by mass spectrometry.

Journal: The Journal of biological chemistry20040402

Title: Galectin-1 induces astrocyte differentiation, which leads to production of brain-derived neurotrophic factor.

Journal: Glycobiology20040401

Title: Protein kinase C modulates negatively the hepatocyte growth factor-induced migration, integrin expression and phosphatidylinositol 3-kinase activation.

Journal: Cellular signalling20040401

Title: Leptin increases cardiomyocyte hyperplasia via extracellular signal-regulated kinase- and phosphatidylinositol 3-kinase-dependent signaling pathways.

Journal: Endocrinology20040401

Title: The first green lineage cdc25 dual-specificity phosphatase.

Journal: Cell cycle (Georgetown, Tex.)20040401

Title: Laminin-2 stimulates the proliferation of epithelial cells in a conjunctival epithelial cell line.

Journal: Cell proliferation20040401

Title: The development of signal transduction pathways during epididymal maturation is calcium dependent.

Journal: Developmental biology20040401

Title: Identification of apoptotic tyrosine-phosphorylated proteins after etoposide or retinoic acid treatment.

Journal: Proteomics20040401

Title: Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects.

Journal: Cancer research20040401

Title: SH2 domains in plants imply new signalling scenarios.

Journal: Trends in plant science20040401

Title: The role of calcium, calcium-activated K+ channels, and tyrosine/kinase in psoralen-evoked responses in human melanoma cells.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas20040401

Title: A homogeneous, nonradioactive high-throughput fluorogenic protein phosphatase assay.

Journal: Journal of biomolecular screening20040401

Title: Epidermal growth factor modulates tyrosine phosphorylation of a novel tensin family member, tensin3.

Journal: Molecular cancer research : MCR20040401

Title: [Phosphotyrosine phosphatase SHP-1, somatostatin and prostate cancer].

Journal: Actas urologicas espanolas20040401

Title: Vascular endothelial cadherin and beta-catenin in human fetoplacental vessels of pregnancies complicated by Type 1 diabetes: associations with angiogenesis and perturbed barrier function.

Journal: Diabetologia20040401

Title: Two-dimensional diversity: screening human cDNA phage display libraries with a random diversity probe for the display cloning of phosphotyrosine binding domains.

Journal: Journal of the American Chemical Society20040331

Title: Effective dephosphorylation of Src substrates by SHP-1.

Journal: The Journal of biological chemistry20040319

Title: Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases.

Journal: Oncogene20040315

Title: Participation of p97Eps8 in Src-mediated transformation.

Journal: The Journal of biological chemistry20040312

Title: Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD.

Journal: The EMBO journal20040310

Title: Localization of Tec29 to ring canals is mediated by Src64 and PtdIns(3,4,5)P3-dependent mechanisms.

Journal: The EMBO journal20040310

Title: Mechanism of platelet-derived growth factor-dependent caveolin-1 phosphorylation: relationship to sterol binding and the role of serine-80.

Journal: Biochemistry20040309

Title: Regulation of the neuronal nicotinic acetylcholine receptor by SRC family tyrosine kinases.

Journal: The Journal of biological chemistry20040305

Title: Cbl-c suppresses v-Src-induced transformation through ubiquitin-dependent protein degradation.

Journal: Oncogene20040304

Title: Residue 182 influences the second step of protein-tyrosine phosphatase-mediated catalysis.

Journal: The Biochemical journal20040301

Title: Upregulation of mRNA in MAPK signaling: transcriptional activation or mRNA stabilization?

Journal: Cell cycle (Georgetown, Tex.)20040301

Title: Wound-induced HB-EGF ectodomain shedding and EGFR activation in corneal epithelial cells.

Journal: Investigative ophthalmology & visual science20040301

Title: Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity.

Journal: Molecular cancer therapeutics20040301

Title: Tensin stabilizes integrin adhesive contacts in Drosophila.

Journal: Developmental cell20040301

Title: AlphaScreen kinase HTS platforms.

Journal: Current medicinal chemistry20040301

Title: Use of high affinity insulin analogues to assess the functional relationships between insulin receptor trafficking, mitogenic signaling and mRNA expression in rat liver.

Journal: Biochimie20040301

Title: The adaptor disabled-2 binds to the third psi xNPxY sequence on the cytoplasmic tail of megalin.

Journal: Biochimie20040301

Title: A boy with autosomal recessive hypercholesterolaemia.

Journal: The Netherlands journal of medicine20040301

Title: Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor.

Journal: The Journal of biological chemistry20040227

Title: Structure-activity relationships of small phosphopeptides, inhibitors of Grb2 SH2 domain, and their prodrugs.

Journal: Journal of medicinal chemistry20040226

Title: A highly conserved NTRK3 C-terminal sequence in the ETV6-NTRK3 oncoprotein binds the phosphotyrosine binding domain of insulin receptor substrate-1: an essential interaction for transformation.

Journal: The Journal of biological chemistry20040220

Title: Structural basis for the specific recognition of RET by the Dok1 phosphotyrosine binding domain.

Journal: The Journal of biological chemistry20040206

Title: Improved biocompatibility of small intestinal submucosa (SIS) following conditioning by human endothelial cells.

Journal: Biomaterials20040201

Title: IL-7 induces tyrosine phosphorylation of clathrin heavy chain.

Journal: Cellular signalling20040201

Title: S1P3-mediated Akt activation and cross-talk with platelet-derived growth factor receptor (PDGFR).

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20040201

Title: Overexpression of profilin reduces the migration of invasive breast cancer cells.

Journal: Cell motility and the cytoskeleton20040201

Title: A zinc-binding dual-specificity YVH1 phosphatase in the malaria parasite, Plasmodium falciparum, and its interaction with the nuclear protein, pescadillo.

Journal: Molecular and biochemical parasitology20040201

Title: Phosphotyrosine phosphoepitopes can be rapidly analyzed by coexpression of a tyrosine kinase in bacteria with a T7 bacteriophage display library.

Journal: Analytical biochemistry20040201

Title: Suppressive effect of regucalcin on protein phosphatase activity in the heart cytosol of normal and regucalcin transgenic rats.

Journal: International journal of molecular medicine20040201

Title: Cyclic AMP-dependent tyrosine phosphorylation in tammar wallaby (Macropus eugenii) spermatozoa.

Journal: Journal of experimental zoology. Part A, Comparative experimental biology20040201

Title: X11alpha impairs gamma- but not beta-cleavage of amyloid precursor protein.

Journal: Journal of neurochemistry20040201

Title: Inactivation of Stat3 in tumor cells: releasing a brake on immune responses against cancer?

Journal: Cancer cell20040201

Title: Antipsoriatic drug anthralin induces EGF receptor phosphorylation in keratinocytes: requirement for H(2)O(2) generation.

Journal: Experimental dermatology20040201

Title: Effect of a Korean traditional formulation, Hwaotang, on superoxide generation in human neutrophils, platelet aggregation in human blood, and nitric oxide, prostaglandin E2 production and paw oedema induced by carrageenan in mice.

Journal: Immunopharmacology and immunotoxicology20040201

Title: Preparation and application of polyclonal and monoclonal sequence-specific anti-phosphoamino acid antibodies.

Journal: Current protocols in protein science20040201

Title: Subdomain X of the kinase domain of Lck binds CD45 and facilitates dephosphorylation.

Journal: The Journal of biological chemistry20040130

Title: Negative regulation of ErbB family receptor tyrosine kinases.

Journal: British journal of cancer20040126

Title: Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems.

Journal: Cell20040123

Title: A cryptic targeting signal induces isoform-specific localization of p46Shc to mitochondria.

Journal: The Journal of biological chemistry20040116

Title: Tyrosine phosphorylation of BIT on photic stimulation in the rat retina.

Journal: FEBS letters20040116

Title: Differential sorting of tyrosine kinases and phosphotyrosine phosphatases acting on band 3 during vesiculation of human erythrocytes.

Journal: The Biochemical journal20040115

Title: Analysis of the mechanism by which calcium negatively regulates the tyrosine phosphorylation cascade associated with sperm capacitation.

Journal: Journal of cell science20040115

Title: Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38.

Journal: Oncogene20040115

Title: Regulation of the dual specificity protein phosphatase, DsPTP1, through interactions with calmodulin.

Journal: The Journal of biological chemistry20040109

Title: Contribution of the membrane-distal tyrosine in intracellular signaling by the granulocyte colony-stimulating factor receptor.

Journal: The Journal of biological chemistry20040102

Title: Probing protein-tyrosine phosphatase substrate specificity using a phosphotyrosine-containing phage library.

Journal: The Journal of biological chemistry20040102

Title: Tensin.

Journal: The international journal of biochemistry & cell biology20040101

Title: Regulation of mechanical interactions between fibroblasts and the substratum by stretch-activated Ca2+ entry.

Journal: Journal of cell science20040101

Title: Distribution of caveolin-1 in bovine lens and redistribution in cultured bovine lens epithelial cells upon confluence.

Journal: Experimental eye research20040101

Title: Green tea polyphenol epigallocatechin-3-gallate inhibits platelet-derived growth factor-induced proliferation of human hepatic stellate cell line LI90.

Journal: Journal of hepatology20040101

Title: Graphical representation and multicomponent analysis of single-frequency fluorescence lifetime imaging microscopy data.

Journal: Journal of microscopy20040101

Title: Trafficking the NGF signal: implications for normal and degenerating neurons.

Journal: Progress in brain research20040101

Title: Dd-STATb, a Dictyostelium STAT protein with a highly aberrant SH2 domain, functions as a regulator of gene expression during growth and early development.

Journal: Development (Cambridge, England)20040101

Title: Coexistence of phosphotyrosine-dependent and -independent interactions between Cbl and Bcr-Abl.

Journal: Experimental hematology20040101

Title: Cloning of a novel signaling molecule, AMSH-2, that potentiates transforming growth factor beta signaling.

Journal: BMC cell biology20040101

Title: Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth.

Journal: Cancer research20040101

Title: Insulin receptor activation and down-regulation by cationic lipid transfection reagents.

Journal: BMC cell biology20040101

Title: Interaction of estrogen receptor alpha with protein kinase C alpha and c-Src in osteoblasts during differentiation.

Journal: Bone20040101

Title: The protein tyrosine phosphatase CD45 is required for interleukin 6 signaling in U266 myeloma cells.

Journal: International journal of hematology20040101

Title: Motility response to insulin-like growth factor-I (IGF-I) in MCF-7 cells is associated with IRS-2 activation and integrin expression.

Journal: Breast cancer research and treatment20040101

Title: A flow cytometric assay for global estimation of tyrosine phosphorylation associated with capacitation of spermatozoa from two marsupial species, the tammar wallaby (Macropus eugenii) and the brushtail possum (Trichosurus vulpecula).

Journal: Reproduction (Cambridge, England)20040101

Title: Acid phosphatase activities during the germination of Glycine max seeds.

Journal: Plant physiology and biochemistry : PPB20040101

Title: Essential function for ErbB3 in breast cancer proliferation.

Journal: Breast cancer research : BCR20040101

Title: Altered signalling thresholds in T lymphocytes cause autoimmune arthritis.

Journal: Arthritis research & therapy20040101

Title: PI3 kinase is important for Ras, MEK and Erk activation of Epo-stimulated human erythroid progenitors.

Journal: BMC biology20040101

Title: A cell-permeable phospholipase Cgamma1-binding peptide transduces neurons and impairs long-term spatial memory.

Journal: Learning & memory (Cold Spring Harbor, N.Y.)20040101

Title: Expression and functional effects of Eph receptor tyrosine kinase A family members on Langerhans like dendritic cells.

Journal: BMC immunology20040101

Title: Proteomic method for identification of tyrosine-nitrated proteins.

Journal: Methods in molecular biology (Clifton, N.J.)20040101

Title: Predicting N-terminal myristoylation sites in plant proteins.

Journal: BMC genomics20040101

Title: Regulation of ErbB4 phosphorylation and cleavage by a novel histidine acid phosphatase.

Journal: Neuroscience20040101

Title: The active metabolite of leflunomide, A771726, inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage.

Journal: Journal of bone and mineral metabolism20040101

Title: Signaling by STATs.

Journal: Arthritis research & therapy20040101

Title: Regulation of restitution after superficial injury in isolated guinea pig gastric mucosa.

Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica20040101

Title: Formin homology 2 domains occur in multiple contexts in angiosperms.

Journal: BMC genomics20040101

Title: Comprehensive de novo structure prediction in a systems-biology context for the archaea Halobacterium sp. NRC-1.

Journal: Genome biology20040101

Title: Investigation of three new mouse mammary tumor cell lines as models for transforming growth factor (TGF)-beta and Neu pathway signaling studies: identification of a novel model for TGF-beta-induced epithelial-to-mesenchymal transition.

Journal: Breast cancer research : BCR20040101

Title: Phosphorylated guanine nucleotide exchange factor C3G, induced by pervanadate and Src family kinases localizes to the Golgi and subcortical actin cytoskeleton.

Journal: BMC cell biology20040101

Title: New approach for analysis of the phosphotyrosine proteome and its application to the chicken B cell line, DT40.

Journal: Journal of proteome research20040101

Title: Reconstruction of ancestral protein sequences and its applications.

Journal: BMC evolutionary biology20040101

Title: Modulation of Rho GTPases by type III secretion system translocated effectors of Yersinia.

Journal: Reviews of physiology, biochemistry and pharmacology20040101

Title: Profiling of generic anti-phosphopeptide antibodies and kinases with peptide microarrays using radioactive and fluorescence-based assays.

Journal: Molecular diversity20040101

Title: Characterization of dual specificity protein kinase from maize seedlings.

Journal: Acta biochimica Polonica20040101

Title: Modeling of cell signaling pathways in macrophages by semantic networks.

Journal: BMC bioinformatics20040101

Title: Comparisons of the M1 genome segments and encoded mu2 proteins of different reovirus isolates.

Journal: Virology journal20040101

Title: Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation.

Journal: BMC biology20040101

Title: Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction.

Journal: Reproductive biology and endocrinology : RB&E20040101

Title: The docking protein Gab1 is the primary mediator of EGF-stimulated activation of the PI-3K/Akt cell survival pathway.

Journal: BMC biology20040101

Title: Protein phosphatase-2A maintains focal adhesion complexes in keratinocytes and the loss of this regulation in squamous cell carcinomas.

Journal: Clinical & experimental metastasis20040101

Title: Regulation of acetylcholine-induced phosphorylation of PLD1 in porcine tracheal smooth muscle.

Journal: Journal of biomedical science20040101

Title: Phospholipids reduce gastric cancer cell adhesion to extracellular matrix in vitro.

Journal: BMC gastroenterology20040101

Title: Ischemia induced focal adhesion kinase cleavage in rat lung.

Journal: Proceedings of the Western Pharmacology Society20040101

Title: Nonspecific association of 2',3'-cyclic nucleotide 3'-phosphodiesterase with the rat forebrain postsynaptic density fraction.

Journal: Experimental & molecular medicine20031231

Title: Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of B and T lymphocyte attenuator required for association with protein tyrosine phosphatases SHP-1 and SHP-2.

Journal: Biochemical and biophysical research communications20031226

Title: Tyrosine phosphorylation of the Rab24 GTPase in cultured mammalian cells.

Journal: Biochemical and biophysical research communications20031219

Title: LMW-PTP associates and dephosphorylates STAT5 interacting with its C-terminal domain.

Journal: Biochemical and biophysical research communications20031212

Title: Hepatocyte growth factor activates several transduction pathways in rat pancreatic acini.

Journal: Biochimica et biophysica acta20031207

Title: Tyrosine phosphorylation of HSP-90 during mammalian sperm capacitation.

Journal: Biology of reproduction20031201

Title: Effect of hyperglycemia on signal transduction in skeletal muscle from diabetic Goto-Kakizaki rats.

Journal: Endocrinology20031201

Title: Phosphatases in concert with kinases set the gain for signal transduction through the T cell receptor.

Journal: Molecular immunology20031201

Title: PTTH-stimulated ecdysone secretion is dependent upon tyrosine phosphorylation in the prothoracic glands of Manduca sexta.

Journal: Insect biochemistry and molecular biology20031201

Title: Cholecystokinin rapidly stimulates CrkII function in vivo in rat pancreatic acini. Formation of CrkII-protein complexes.

Journal: European journal of biochemistry20031201

Title: Fc epsilon RI signaling of mast cells activates intracellular production of hydrogen peroxide: role in the regulation of calcium signals.

Journal: Journal of immunology (Baltimore, Md. : 1950)20031201

Title: Alternagin-C, a nonRGD-disintegrin, induces neutrophil migration via integrin signaling.

Journal: European journal of biochemistry20031201

Title: Angiotensin II mediates Tyr-dephosphorylation in rat fetal kidney membranes.

Journal: Molecular and cellular biochemistry20031201

Title: A novel competitive ELISA for both free and protein-bound nitrotyrosine.

Journal: Hybridoma and hybridomics20031201

Title: Down-regulation of platelet-derived growth factor receptor signaling during myogenesis.

Journal: Cellular and molecular life sciences : CMLS20031201

Title: Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.

Journal: Molecular cell20031201

Title: The cholecystokinin system in the rat retina: receptor expression and in vivo activation of tyrosine phosphorylation pathways.

Journal: Neuropeptides20031201

Title: Src-dependent phosphorylation of the EGF receptor Tyr-845 mediates Stat-p21waf1 pathway in A431 cells.

Journal: Genes to cells : devoted to molecular & cellular mechanisms20031201

Title: Identification of PSD-93 as a substrate for the Src family tyrosine kinase Fyn.

Journal: The Journal of biological chemistry20031128

Title: Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.

Journal: Journal of medicinal chemistry20031120

Title: High-resolution structure of the Yersinia pestis protein tyrosine phosphatase YopH in complex with a phosphotyrosyl mimetic-containing hexapeptide.

Journal: Biochemistry20031118

Title: Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells.

Journal: Journal of cell science20031115

Title: Uncoupling between immunological synapse formation and functional outcome in human gamma delta T lymphocytes.

Journal: Journal of immunology (Baltimore, Md. : 1950)20031115

Title: Xenopus autosomal recessive hypercholesterolemia protein couples lipoprotein receptors with the AP-2 complex in oocytes and embryos and is required for vitellogenesis.

Journal: The Journal of biological chemistry20031107

Title: Phosphoprotein phosphatase of Mycobacterium tuberculosis dephosphorylates serine-threonine kinases PknA and PknB.

Journal: Biochemical and biophysical research communications20031107

Title: Attenuated signaling by a phosphotyrosine-null Epo receptor form in primary erythroid progenitor cells.

Journal: Blood20031101

Title: Src mediates prolactin-dependent proliferation of T47D and MCF7 cells via the activation of focal adhesion kinase/Erk1/2 and phosphatidylinositol 3-kinase pathways.

Journal: Molecular endocrinology (Baltimore, Md.)20031101

Title: Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor.

Journal: Molecular endocrinology (Baltimore, Md.)20031101

Title: Janus kinase 2 determinants for growth hormone receptor association, surface assembly, and signaling.

Journal: Molecular endocrinology (Baltimore, Md.)20031101

Title: Proteomic approaches to the analysis of early events in colony-stimulating factor-1 signal transduction.

Journal: Molecular & cellular proteomics : MCP20031101

Title: Transactivation of epidermal growth factor receptor after heparin-binding epidermal growth factor-like growth factor shedding in the migration of prostate cancer cells promoted by bombesin.

Journal: The Prostate20031101

Title: Oxygen radical production in neutrophils interacting with platelets and surface-immobilized plasma proteins: role of tyrosine phosphorylation.

Journal: Journal of biomedical materials research. Part A20031101

Title: Apoptosis of lymphocytes induced by chromium(VI/V) is through ROS-mediated activation of Src-family kinases and caspase-3.

Journal: Free radical biology & medicine20031101

Title: Tyrosine 116 of the herpes simplex virus type 1 IEalpha22 protein is an ocular virulence determinant and potential phosphorylation site.

Journal: Investigative ophthalmology & visual science20031101

Title: Potent and selective inhibitors of the Met [hepatocyte growth factor/scatter factor (HGF/SF) receptor] tyrosine kinase block HGF/SF-induced tumor cell growth and invasion.

Journal: Molecular cancer therapeutics20031101

Title: Involvement of oligosaccharide changes in alpha5beta1 integrin in a cisplatin-resistant human squamous cell carcinoma cell line.

Journal: Molecular cancer therapeutics20031101

Title: Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development.

Journal: PLoS biology20031101

Title: T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression.

Journal: PLoS biology20031101

Title: Differences and similarities in tyrosine phosphorylation of proteins in platelets from human and pig species.

Journal: Journal of thrombosis and haemostasis : JTH20031101

Title: Combinatorial chemistry.

Journal: Drug discovery today20031101

Title: Amyloid beta peptide specifically promotes phosphorylation and nuclear translocation of the extracellular signal-regulated kinase in cultured rat cortical astrocytes.

Journal: Journal of pharmacological sciences20031101

Title: The antidiabetic agent sodium tungstate activates glycogen synthesis through an insulin receptor-independent pathway.

Journal: The Journal of biological chemistry20031031

Title: Hypoxia activates signal transducers and activators of transcription 5 (STAT5) and increases its binding activity to the GAS element in mammary epithelial cells.

Journal: Experimental & molecular medicine20031031

Title: FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies.

Journal: Neuron20031030

Title: [p120(ctn) tyrosine phosphorylation are involved in the biologic behavior changes of hepatocellular carcinoma cells].

Journal: Zhonghua yi xue za zhi20031025

Title: An SH2 domain-dependent, phosphotyrosine-independent interaction between Vav1 and the Mer receptor tyrosine kinase: a mechanism for localizing guanine nucleotide-exchange factor action.

Journal: The Journal of biological chemistry20031024

Title: Design and synthesis of small chemical inhibitors containing different scaffolds for lck SH2 domain.

Journal: Bioorganic & medicinal chemistry letters20031020

Title: Nuclear shift of hnRNP K protein in neoplasms and other states of enhanced cell proliferation.

Journal: British journal of cancer20031020

Title: Roles for an Epo receptor Tyr-343 Stat5 pathway in proliferative co-signaling with kit.

Journal: The Journal of biological chemistry20031017

Title: The UIM domain of Hrs couples receptor sorting to vesicle formation.

Journal: Journal of cell science20031015

Title: A cleanup step maximizes the immunoprecipitation of tyrosine-phosphorylated peptides by a conventional antiphosphotyrosine antibody.

Journal: Analytical biochemistry20031015

Title: Reactive oxygen species promote tyrosine phosphorylation and capacitation in equine spermatozoa.

Journal: Theriogenology20031015

Title: The hemopoietic Rho/Rac guanine nucleotide exchange factor Vav1 regulates N-formyl-methionyl-leucyl-phenylalanine-activated neutrophil functions.

Journal: Journal of immunology (Baltimore, Md. : 1950)20031015

Title: Antitumor effects of epidermal growth factor receptor antisense oligonucleotides in combination with docetaxel in squamous cell carcinoma of the head and neck.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20031015

Title: The phosphotyrosine phosphatase SHP2 is a critical mediator of transformation induced by the oncogenic fibroblast growth factor receptor 3.

Journal: Oncogene20031009

Title: FGFR3IIIS: a novel soluble FGFR3 spliced variant that modulates growth is frequently expressed in tumour cells.

Journal: British journal of cancer20031006

Title: Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1.

Journal: The Journal of biological chemistry20031003

Title: Effects of deficiencies of STAMs and Hrs, mammalian class E Vps proteins, on receptor downregulation.

Journal: Biochemical and biophysical research communications20031003

Title: Grb2 regulation of the actin-based cytoskeleton is required for ligand-independent EGF receptor-mediated oncogenesis.

Journal: Oncogene20031002

Title: Characterization of insulin signaling in rat retina in vivo and ex vivo.

Journal: American journal of physiology. Endocrinology and metabolism20031001

Title: Recruitment of endothelial caveolae into mechanotransduction pathways by flow conditioning in vitro.

Journal: American journal of physiology. Heart and circulatory physiology20031001

Title: STAT1 plays an essential role in LPS/D-galactosamine-induced liver apoptosis and injury.

Journal: American journal of physiology. Gastrointestinal and liver physiology20031001

Title: Aging-related attenuation of EGF receptor signaling is mediated in part by increased protein tyrosine phosphatase activity.

Journal: Experimental cell research20031001

Title: Keap1 in adhesion complexes.

Journal: Cell motility and the cytoskeleton20031001

Title: Basic fibroblast and epidermal growth factors stimulate survival in adult porcine photoreceptor cell cultures.

Journal: Investigative ophthalmology & visual science20031001

Title: Rapid and sensitive identification of epitope-containing peptides by direct matrix-assisted laser desorption/ionization tandem mass spectrometry of peptides affinity-bound to antibody beads.

Journal: Journal of the American Society for Mass Spectrometry20031001

Title: Light regulation of the insulin receptor in the retina.

Journal: Molecular neurobiology20031001

Title: Aged mice exhibit distinct B cell precursor phenotypes differing in activation, proliferation and apoptosis.

Journal: Experimental gerontology20031001

Title: Relationship between phosphatase activity and cytotoxic effect of two protein phosphatase inhibitors, okadaic acid and pervanadate, on human myeloid leukemia cell line.

Journal: Journal of enzyme inhibition and medicinal chemistry20031001

Title: Plasma membrane phospholipid scramblase 1 promotes EGF-dependent activation of c-Src through the epidermal growth factor receptor.

Journal: The Journal of biological chemistry20030926

Title: Fragment screening and assembly: a highly efficient approach to a selective and cell active protein tyrosine phosphatase 1B inhibitor.

Journal: Journal of medicinal chemistry20030925

Title: Lymphocyte function-associated antigen-1-mediated T cell adhesion is impaired by low molecular weight phosphotyrosine phosphatase-dependent inhibition of FAK activity.

Journal: The Journal of biological chemistry20030919

Title: Her-2/neu-triggered intracellular tyrosine kinase activation: in vivo relevance of ligand-independent activation mechanisms and impact upon the efficacy of trastuzumab-based treatment.

Journal: British journal of cancer20030915

Title: Transmembrane modulator-dependent bacterial tyrosine kinase activates UDP-glucose dehydrogenases.

Journal: The EMBO journal20030915

Title: p130Cas Couples the tyrosine kinase Bmx/Etk with regulation of the actin cytoskeleton and cell migration.

Journal: The Journal of biological chemistry20030912

Title: Integrin alpha 4 beta 1-dependent T cell migration requires both phosphorylation and dephosphorylation of the alpha 4 cytoplasmic domain to regulate the reversible binding of paxillin.

Journal: The Journal of biological chemistry20030912

Title: Cholecystokinin-stimulated protein kinase C-delta kinase activation, tyrosine phosphorylation, and translocation are mediated by Src tyrosine kinases in pancreatic acinar cells.

Journal: The Journal of biological chemistry20030912

Title: PAR-2 modulates pepsinogen secretion from gastric-isolated chief cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology20030901

Title: dDYRK2: a novel dual-specificity tyrosine-phosphorylation-regulated kinase in Drosophila.

Journal: The Biochemical journal20030901

Title: Low molecular weight phosphotyrosine protein phosphatase from PC12 cells. Purification, some properties and expression during neurogenesis in vitro and in vivo.

Journal: The international journal of biochemistry & cell biology20030901

Title: Cholesterol dependence of vascular ERK1/2 activation and growth in response to stretch: role of endothelin-1.

Journal: Arteriosclerosis, thrombosis, and vascular biology20030901

Title: Tyrosine kinase mediated phosphorylation of the hexamerin receptor in the rice moth Corcyra cephalonica by ecdysteroids.

Journal: Insect biochemistry and molecular biology20030901

Title: Vascular endothelial growth factor expression and signaling in the lens.

Journal: Investigative ophthalmology & visual science20030901

Title: Helicobacter pylori CagA as a potential bacterial oncoprotein in gastric carcinogenesis.

Journal: Pathologie-biologie20030901

Title: Studies of ligand-induced site-specific phosphorylation of epidermal growth factor receptor.

Journal: Journal of the American Society for Mass Spectrometry20030901

Title: Identification and functional assessment of novel and known insulin receptor mutations in five patients with syndromes of severe insulin resistance.

Journal: The Journal of clinical endocrinology and metabolism20030901

Title: Mouse lipocalin as an enhancer of spermatozoa motility.

Journal: Molecular biology reports20030901

Title: Redox regulation of protein tyrosine phosphatases during receptor tyrosine kinase signal transduction.

Journal: Trends in biochemical sciences20030901

Title: Inhibition of interferon gamma signaling by the short chain fatty acid butyrate.

Journal: Molecular cancer research : MCR20030901

Title: Ionizing radiation modules of the expression and tyrosine phosphorylation of the focal adhesion-associated proteins focal adhesion kinase (FAK) and its substrates p130cas and paxillin in A549 human lung carcinoma cells in vitro.

Journal: International journal of radiation biology20030901

Title: 2', 3'-cyclic nucleotide 3'-phosphodiesterase is expressed in dissociated rat cerebellar cells and included in the postsynaptic density fraction.

Journal: Molecules and cells20030831

Title: Flagellar adhesion between mating type plus and mating type minus gametes activates a flagellar protein-tyrosine kinase during fertilization in Chlamydomonas.

Journal: The Journal of biological chemistry20030829

Title: Sensitivity of rabbit aorta and mesenteric artery to norepinephrine: role of tyrosine kinases.

Journal: European journal of pharmacology20030829

Title: Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck.

Journal: The Journal of biological chemistry20030822

Title: Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling.

Journal: The Journal of biological chemistry20030822

Title: Concise and enantioselective synthesis of Fmoc-Pmp(But)2-OH and design of potent Pmp-containing Grb2-SH2 domain antagonists.

Journal: Organic letters20030821

Title: The noncatalytic domains of Lck regulate its dephosphorylation by CD45.

Journal: Biochimica et biophysica acta20030821

Title: Feedback regulation of MAPK signalling by an RNA-binding protein.

Journal: Nature20030821

Title: 4-Hydroxycoumarin disorganizes the actin cytoskeleton in B16-F10 melanoma cells but not in B82 fibroblasts, decreasing their adhesion to extracellular matrix proteins and motility.

Journal: Cancer letters20030820

Title: Selective inhibition of T cell activation via CD147 through novel modulation of lipid rafts.

Journal: Journal of immunology (Baltimore, Md. : 1950)20030815

Title: Intracellular domain of brain endothelial intercellular adhesion molecule-1 is essential for T lymphocyte-mediated signaling and migration.

Journal: Journal of immunology (Baltimore, Md. : 1950)20030815

Title: Grb2-independent recruitment of Gab1 requires the C-terminal lobe and structural integrity of the Met receptor kinase domain.

Journal: The Journal of biological chemistry20030808

Title: Structural basis for a non-phosphorus-containing cyclic peptide binding to Grb2-SH2 domain with high affinity.

Journal: Biochemical and biophysical research communications20030808

Title: Nitric oxide-induced inhibition of aortic smooth muscle cell motility: role of PTP-PEST and adaptor proteins p130cas and Crk.

Journal: American journal of physiology. Heart and circulatory physiology20030801

Title: Focal adhesion kinase is required for endothelin-induced cell cycle progression of cultured astrocytes.

Journal: Glia20030801

Title: Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation.

Journal: Traffic (Copenhagen, Denmark)20030801

Title: Functional characterization of W147A: a high-affinity interleukin-11 antagonist.

Journal: Endocrinology20030801

Title: Protein tyrosine phosphatase 1B inhibition: opportunities and challenges.

Journal: Current medicinal chemistry20030801

Title: Differential analysis of phosphorylated proteins in resting and thrombin-stimulated human platelets.

Journal: Analytical and bioanalytical chemistry20030801

Title: Coupling of folding and binding in the PTB domain of the signaling protein Shc.

Journal: Structure (London, England : 1993)20030801

Title: Parathyroid hormone-related peptide modulates signal pathways in skin and hair follicle cells.

Journal: Experimental dermatology20030801

Title: Tyrosine phosphate in melanoma progression.

Journal: The British journal of dermatology20030801

Title: Staining proteins in gels.

Journal: Current protocols in molecular biology20030801

Title: Selective protein tyrosine phosphatase 1B inhibitors: targeting the second phosphotyrosine binding site with non-carboxylic acid-containing ligands.

Journal: Journal of medicinal chemistry20030731

Title: Cell shape provides global control of focal adhesion assembly.

Journal: Biochemical and biophysical research communications20030725

Title: Relevance of Akt phosphorylation in cell transformation induced by Jaagsiekte sheep retrovirus.

Journal: Virology20030720

Title: Evolution of key cell signaling and adhesion protein families predates animal origins.

Journal: Science (New York, N.Y.)20030718

Title: PTPRQ is a novel phosphatidylinositol phosphatase that can be expressed as a cytoplasmic protein or as a subcellularly localized receptor-like protein.

Journal: Experimental cell research20030715

Title: SH2 and PTB domains in tyrosine kinase signaling.

Journal: Science's STKE : signal transduction knowledge environment20030715

Title: Identification and characterization of signal transducer and activator of transcription 3 recruitment sites within the epidermal growth factor receptor.

Journal: Cancer research20030715

Title: Changes in L1 and NCAM expression in the rat suprachiasmatic nucleus during growth and after orbital enucleation.

Journal: Brain research. Developmental brain research20030712

Title: The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region.

Journal: Biochemistry20030708

Title: Engineering a 'methionine clamp' into Src family kinases enhances specificity toward unnatural ATP analogues.

Journal: Biochemistry20030708

Title: Potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics.

Journal: Bioorganic & medicinal chemistry letters20030707

Title: Directed evolution of a yeast arsenate reductase into a protein-tyrosine phosphatase.

Journal: The Journal of biological chemistry20030704

Title: A differential mechanism is involved during heparin- and cryopreservation-induced capacitation of bovine spermatozoa.

Journal: Biology of reproduction20030701

Title: Protein tyrosine phosphatase activity regulates endothelial cell-cell interactions, the paracellular pathway, and capillary tube stability.

Journal: American journal of physiology. Lung cellular and molecular physiology20030701

Title: Correlation of P-cadherin and beta-catenin expression and phosphorylation with carcinogenesis in rat tongue cancer induced with 4-nitroquinoline 1-oxide.

Journal: Oral oncology20030701

Title: Novel stimulatory actions of the phytoestrogen genistein: effects on the gain of cardiac excitation-contraction coupling.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20030701

Title: EGF receptor-mediated, c-Src-dependent, activation of Stat5b is downregulated in mitogenically responsive hepatocytes.

Journal: Journal of cellular physiology20030701

Title: Differential regulation of junctional complex assembly in renal epithelial cell lines.

Journal: American journal of physiology. Cell physiology20030701

Title: An ecto-protein tyrosine phosphatase of Entamoeba histolytica induces cellular detachment by disruption of actin filaments in HeLa cells.

Journal: International journal for parasitology20030701

Title: Copper-homocysteine complexes and potential physiological actions.

Journal: Journal of inorganic biochemistry20030701

Title: Effect of phosphotyrosine proteins on phorbol myristate acetate-induced NADPH oxidase activation in guinea pig peritoneal polymorphonuclear leukocytes.

Journal: Biological & pharmaceutical bulletin20030701

Title: Interleukin-10 activation of the interleukin-10E1 pathway and tissue inhibitor of metalloproteinase-1 expression is enhanced by proteasome inhibitors in primary prostate tumor lines.

Journal: Molecular cancer research : MCR20030701

Title: Platelet proteomics.

Journal: Journal of thrombosis and haemostasis : JTH20030701

Title: A conformational switch controls the DNA cleavage activity of lambda integrase.

Journal: Molecular cell20030701

Title: Protein phosphorylation during the process of interaction of Toxoplasma gondii with host cells.

Journal: Journal of submicroscopic cytology and pathology20030701

Title: Utilization of a beta-aminophosphotyrosyl mimetic in the design and synthesis of macrocyclic Grb2 SH2 domain-binding peptides.

Journal: Journal of medicinal chemistry20030619

Title: Design and synthesis of phosphotyrosine mimetics.

Journal: Bioorganic & medicinal chemistry letters20030616

Title: Alternative splicing variants of dual specificity tyrosine phosphorylated and regulated kinase 1B exhibit distinct patterns of expression and functional properties.

Journal: The Biochemical journal20030615

Title: Polyvalent antigens stabilize B cell antigen receptor surface signaling microdomains.

Journal: Journal of immunology (Baltimore, Md. : 1950)20030615

Title: c-Cbl is a critical modulator of the Ron tyrosine kinase receptor.

Journal: Oncogene20030612

Title: IL-10 signaling via IL-10E1 is dependent on tyrosine phosphorylation in the IL-10R alpha chain in human primary prostate cancer cell lines.

Journal: Oncogene20030612

Title: Dynamics and DNA substrate recognition by the catalytic domain of lambda integrase.

Journal: Journal of molecular biology20030606

Title: Interleukin-4 and interleukin-13 signaling connections maps.

Journal: Science (New York, N.Y.)20030606

Title: Potent, selective inhibitors of protein tyrosine phosphatase 1B.

Journal: Bioorganic & medicinal chemistry letters20030602

Title: A cholesterol-regulated PP2A/HePTP complex with dual specificity ERK1/2 phosphatase activity.

Journal: The EMBO journal20030602

Title: Post-mortem interval effects on the phosphorylation of signaling proteins.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology20030601

Title: Commentary: effect of flavonoids on normal and leukemic cells.

Journal: Leukemia research20030601

Title: Cyclic phosphatidic acid inhibits RhoA-mediated autophosphorylation of FAK at Tyr-397 and subsequent tumor-cell invasion.

Journal: International journal of oncology20030601

Title: IL-21 in synergy with IL-15 or IL-18 enhances IFN-gamma production in human NK and T cells.

Journal: Journal of immunology (Baltimore, Md. : 1950)20030601

Title: Thiol-modifying phenylarsine oxide inhibits guanine nucleotide binding of Rho but not of Rac GTPases.

Journal: Molecular pharmacology20030601

Title: Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes.

Journal: Diabetes20030601

Title: Insulin receptor substrate-4 signaling in quiescent rat hepatocytes and in regenerating rat liver.

Journal: Hepatology (Baltimore, Md.)20030601

Title: The FRK/RAK-SHB signaling cascade: a versatile signal-transduction pathway that regulates cell survival, differentiation and proliferation.

Journal: Current molecular medicine20030601

Title: Fragmentation of cationized phosphotyrosine containing peptides by atmospheric pressure MALDI/Ion trap mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry20030601

Title: Phosphotyrosyl mimetics in the development of signal transduction inhibitors.

Journal: Accounts of chemical research20030601

Title: Analysis of protein tyrosine phosphorylation by nanoelectrospray ionization high-resolution tandem mass spectrometry and tyrosine-targeted product ion scanning.

Journal: Analytical chemistry20030601

Title: The EphA8 receptor phosphorylates and activates low molecular weight phosphotyrosine protein phosphatase in vitro.

Journal: Journal of biochemistry and molecular biology20030531

Title: Receptor tyrosine kinase Axl modulates the osteogenic differentiation of pericytes.

Journal: Circulation research20030530

Title: Naringenin inhibits phosphoinositide 3-kinase activity and glucose uptake in 3T3-L1 adipocytes.

Journal: Biochemical and biophysical research communications20030530

Title: Thymidine phosphorylase and 2-deoxyribose stimulate human endothelial cell migration by specific activation of the integrins alpha 5 beta 1 and alpha V beta 3.

Journal: The Journal of biological chemistry20030523

Title: Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells. Modulation of EGF-induced trafficking and signaling.

Journal: The Journal of biological chemistry20030523

Title: Matrix-independent activation of phosphatidylinositol 3-kinase, Stat3, and cyclin A-associated Cdk2 Is essential for anchorage-independent growth of v-Ros-transformed chicken embryo fibroblasts.

Journal: The Journal of biological chemistry20030523

Title: Phosphospecific site tyrosine phosphorylation of p125FAK and proline-rich kinase 2 is differentially regulated by cholecystokinin receptor type A activation in pancreatic acini.

Journal: The Journal of biological chemistry20030523

Title: Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B.

Journal: Journal of medicinal chemistry20030522

Title: Filopodial calcium transients regulate growth cone motility and guidance through local activation of calpain.

Journal: Neuron20030522

Title: L-type voltage-gated calcium channel attends regulation of tyrosine phosphorylation of NMDA receptor subunit 2A induced by transient brain ischemia.

Journal: Brain research20030516

Title: Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase.

Journal: Oncogene20030515

Title: Focal adhesions and associated proteins in medullary thyroid carcinoma cells.

Journal: The Journal of surgical research20030515

Title: Smooth muscle cell migration stimulated by interleukin 6 is associated with cytoskeletal reorganization.

Journal: The Journal of surgical research20030515

Title: Discovery of a new phosphotyrosine mimetic for PTP1B using breakaway tethering.

Journal: Journal of the American Chemical Society20030514

Title: Molecular dynamics, free energy, and SPR analyses of the interactions between the SH2 domain of Grb2 and ErbB phosphotyrosyl peptides.

Journal: Biochemistry20030513

Title: Analysis of the leukemia inhibitory factor receptor functional domains by chimeric receptors and cytokines.

Journal: Biochemistry20030513

Title: Chemical dissection of the effects of tyrosine phosphorylation of SHP-2.

Journal: Biochemistry20030513

Title: Peptidyl aldehydes as reversible covalent inhibitors of SRC homology 2 domains.

Journal: Biochemistry20030506

Title: Characterization of phosphopeptide motifs specific for the Src homology 2 domains of signal transducer and activator of transcription 1 (STAT1) and STAT3.

Journal: The Journal of biological chemistry20030502

Title: Phosphoinositide 3-kinase-mediated reduction of insulin receptor substrate-1/2 protein expression via different mechanisms contributes to the insulin-induced desensitization of its signaling pathways in L6 muscle cells.

Journal: The Journal of biological chemistry20030502

Title: The mRNA transcription/processing factor Ssu72 is a potential tyrosine phosphatase.

Journal: The Journal of biological chemistry20030502

Title: Structural and thermodynamic basis for the interaction of the Src SH2 domain with the activated form of the PDGF beta-receptor.

Journal: Journal of molecular biology20030502

Title: Radiation stimulates HGF receptor/c-Met expression that leads to amplifying cellular response to HGF stimulation via upregulated receptor tyrosine phosphorylation and MAP kinase activity in pancreatic cancer cells.

Journal: International journal of cancer20030501

Title: Platelet derived growth factor (PDGF) responsive epidermis formed from human keratinocytes transduced with the PDGF beta receptor gene.

Journal: The Journal of investigative dermatology20030501

Title: Effect of in vivo administered hexachlorobenzene on epidermal growth factor receptor levels, protein tyrosine kinase activity, and phosphotyrosine content in rat liver.

Journal: Biochemical pharmacology20030501

Title: Examining both sides of a Janus PTB domain.

Journal: Structure (London, England : 1993)20030501

Title: Increased ubiquitination and reduced expression of LCK in T lymphocytes from patients with systemic lupus erythematosus.

Journal: Arthritis and rheumatism20030501

Title: SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer.

Journal: Molecular cancer therapeutics20030501

Title: Selective adhesion of osteoblastic cells to different integrin ligands induces osteopontin gene expression.

Journal: Matrix biology : journal of the International Society for Matrix Biology20030501

Title: Fibroblast growth factor-2-induced signaling through lipid raft-associated fibroblast growth factor receptor substrate 2 (FRS2).

Journal: The Journal of biological chemistry20030418

Title: Development of an efficient 'substrate-trapping' mutant of Src homology phosphotyrosine phosphatase 2 and identification of the epidermal growth factor receptor, Gab1, and three other proteins as target substrates.

Journal: The Journal of biological chemistry20030418

Title: RhoA and ROCK promote migration by limiting membrane protrusions.

Journal: The Journal of biological chemistry20030411

Title: Ethanol feeding induces insulin resistance with enhanced PI 3-kinase activation.

Journal: Biochemical and biophysical research communications20030411

Title: An experimental and theoretical study of the 13C and 31P chemical shielding tensors in solid O-phosphorylated amino acids.

Journal: Journal of the American Chemical Society20030409

Title: Activation of phospholipase D is not mediated by direct phosphorylation on tyrosine residues.

Journal: Biochimica et biophysica acta20030408

Title: Redox modulation of protein kinase/phosphatase balance in melanoma cells: the role of endogenous and gamma-glutamyltransferase-dependent H2O2 production.

Journal: Biochimica et biophysica acta20030407

Title: The antiinflammatory endothelial tyrosine kinase Tie2 interacts with a novel nuclear factor-kappaB inhibitor ABIN-2.

Journal: Circulation research20030404

Title: TMC-264, a novel antiallergic heptaketide produced by the fungus Phoma sp. TC 1674.

Journal: Organic letters20030403

Title: Genetic identification of effectors downstream of Neu (ErbB-2) autophosphorylation sites in a Drosophila model.

Journal: Oncogene20030403

Title: Positive and negative regulation of T-cell activation through kinases and phosphatases.

Journal: The Biochemical journal20030401

Title: Development of the signalling pathways associated with sperm capacitation during epididymal maturation.

Journal: Molecular reproduction and development20030401

Title: Localization of tyrosine phosphorylated proteins in human sperm and relation to capacitation and zona pellucida binding.

Journal: Biology of reproduction20030401

Title: Molecular mechanisms of autosomal recessive hypercholesterolemia.

Journal: Current opinion in lipidology20030401

Title: Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance.

Journal: Diabetes20030401

Title: Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 activity exerts an antidiabetic action in Goto-Kakizaki rats.

Journal: Diabetes20030401

Title: Sensitivity to imatinib but low frequency of the TEL/PDGFRbeta fusion protein in chronic myelomonocytic leukemia.

Journal: Haematologica20030401

Title: A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20030401

Title: Constitutive activation of Jak2 contributes to proliferation and resistance to apoptosis in NPM/ALK-transformed cells.

Journal: Experimental hematology20030401

Title: Nitric oxide-induced epidermal growth factor-dependent phosphorylations in A431 tumour cells.

Journal: European journal of biochemistry20030401

Title: Hyperoxia alters phorbol ester-induced phospholipase D activation in bovine lung microvascular endothelial cells.

Journal: Antioxidants & redox signaling20030401

Title: Relationship between cardiac protein tyrosine phosphorylation and myofibrillogenesis during axolotl heart development.

Journal: Tissue & cell20030401

Title: Profiling the global tyrosine phosphorylation state.

Journal: Molecular & cellular proteomics : MCP20030401

Title: Incidence of sperm-tail tyrosine phosphorylation and hyperactivated motility in normozoospermic and asthenozoospermic human sperm samples.

Journal: Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al20030401

Title: Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation.

Journal: The Journal of biological chemistry20030328

Title: Tyrosine dephosphorylation and ethanol inhibition of N-Methyl-D-aspartate receptor function.

Journal: The Journal of biological chemistry20030328

Title: Phosphatase activity characterization on the surface of intact bloodstream forms of Trypanosoma brucei.

Journal: FEMS microbiology letters20030328

Title: Early intracellular events induced by in vivo leptin treatment in mouse skeletal muscle.

Journal: Molecular and cellular endocrinology20030328

Title: Mechanism of inhibition of site-specific recombination by the Holliday junction-trapping peptide WKHYNY: insights into phage lambda integrase-mediated strand exchange.

Journal: Journal of molecular biology20030321

Title: A myristoyl/phosphotyrosine switch regulates c-Abl.

Journal: Cell20030321

Title: Structural basis for the autoinhibition of c-Abl tyrosine kinase.

Journal: Cell20030321

Title: A constitutively active ErbB4 mutant inhibits drug-resistant colony formation by the DU-145 and PC-3 human prostate tumor cell lines.

Journal: Cancer letters20030320

Title: Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption.

Journal: Journal of cell science20030315

Title: MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models.

Journal: Blood20030315

Title: Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3.

Journal: Journal of immunology (Baltimore, Md. : 1950)20030315

Title: Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice.

Journal: Cancer research20030315

Title: The function of the protein tyrosine phosphatase SHP-1 in cancer.

Journal: Gene20030313

Title: Structure-based design of thioether-bridged cyclic phosphopeptides binding to Grb2-SH2 domain.

Journal: Bioorganic & medicinal chemistry letters20030310

Title: Loss of ligand-binding specificity of fibroblast growth factor receptor 2 by RNA splicing in human chondrosarcoma cells.

Journal: Cancer letters20030310

Title: Cysteine residues in the C-terminal lobe of Src: their role in the suppression of the Src kinase.

Journal: Oncogene20030306

Title: The Polycomb-group protein ENX-2 interacts with ZAP-70.

Journal: Immunology letters20030303

Title: c-Abl is required for oxidative stress-induced phosphorylation of caveolin-1 on tyrosine 14.

Journal: Cellular signalling20030301

Title: The adaptor function of SHP-2 downstream of the prolactin receptor is required for the recruitment of p29, a substrate of SHP-2.

Journal: Cellular signalling20030301

Title: Interaction of the growth hormone receptor with cytokine-induced Src homology domain 2 protein in rat adipocytes.

Journal: Endocrinology20030301

Title: WW domain sequence activity relationships identified using ligand recognition propensities of 42 WW domains.

Journal: Protein science : a publication of the Protein Society20030301

Title: Soy-derived isoflavones exert opposing actions on Guinea pig ventricular myocytes.

Journal: The Journal of pharmacology and experimental therapeutics20030301

Title: Role of protein tyrosine phosphorylation in the thapsigargin-induced intracellular Ca(2+) store depletion during human sperm acrosome reaction.

Journal: Molecular human reproduction20030301

Title: The extracellular portion of the insulin receptor beta-subunit regulates the cellular trafficking of the insulin-insulin receptor complex. Studies on Chinese hamster ovary cells carrying the Cys 860-->Ser insulin receptor mutation.

Journal: European journal of endocrinology20030301

Title: Analysis of tyrosine phosphorylation in resident peritoneal cells during diet restriction by laser scanning cytometry.

Journal: Shock (Augusta, Ga.)20030301

Title: Phosphotyrosine mapping in Bcr/Abl oncoprotein using phosphotyrosine-specific immonium ion scanning.

Journal: Molecular & cellular proteomics : MCP20030301

Title: Detection of tyrosine phosphorylated peptides via skimmer collision-induced dissociation/ion trap mass spectrometry.

Journal: Journal of mass spectrometry : JMS20030301

Title: Evidence for a direct effect of captopril on early steps of insulin action in BC3H-1 myocytes.

Journal: Metabolism: clinical and experimental20030301

Title: 1H, 15N and 13C resonance assignments for the PTB domain of the signaling protein Shc.

Journal: Journal of biomolecular NMR20030301

Title: Membrane-bound acid phosphatase (MAP) from Entamoeba histolytica has phosphotyrosine phosphatase activity and disrupts the actin cytoskeleton of host cells.

Journal: Parasitology20030301

Title: Diversity in the SH2 domain family phosphotyrosyl peptide binding site.

Journal: Protein engineering20030301

Title: Involvement of the tyrosine phosphorylation on GSH transport in NIH3T3 fibroblasts.

Journal: IUBMB life20030301

Title: Follicle-stimulating hormone activates extracellular signal-regulated kinase but not extracellular signal-regulated kinase kinase through a 100-kDa phosphotyrosine phosphatase.

Journal: The Journal of biological chemistry20030227

Title: The pp60c-Src inhibitor PP1 is non-competitive against ATP.

Journal: FEBS letters20030227

Title: Hepatocyte growth factor receptor tyrosine kinase met is a substrate of the receptor protein-tyrosine phosphatase DEP-1.

Journal: The Journal of biological chemistry20030221

Title: Syk, a protein-tyrosine kinase, suppresses the cell motility and nuclear factor kappa B-mediated secretion of urokinase type plasminogen activator by inhibiting the phosphatidylinositol 3'-kinase activity in breast cancer cells.

Journal: The Journal of biological chemistry20030221

Title: Crystal structure of human protein-tyrosine phosphatase SHP-1.

Journal: The Journal of biological chemistry20030221

Title: The role of C-terminal tyrosine phosphorylation in the regulation of SHP-1 explored via expressed protein ligation.

Journal: The Journal of biological chemistry20030214

Title: Structural plasticity of the Flp-Holliday junction complex.

Journal: Journal of molecular biology20030214

Title: The Shb adaptor protein causes Src-dependent cell spreading and activation of focal adhesion kinase in murine brain endothelial cells.

Journal: Cellular signalling20030201

Title: Angiotensin II effects on STAT3 phosphorylation in cardiomyocytes: evidence for Erk-dependent Tyr705 dephosphorylation.

Journal: Basic research in cardiology20030201

Title: Purification and characterization of a protein tyrosine acid phosphatase from boar seminal vesicle glands.

Journal: Theriogenology20030201

Title: Suppressive effect of endogenous regucalcin on protein tyrosine phosphatase activity in the nucleus of rat brain: attenuation with increasing age.

Journal: International journal of molecular medicine20030201

Title: Low free energy cost of very long loop insertions in proteins.

Journal: Protein science : a publication of the Protein Society20030201

Title: Prediction of secondary ionization of the phosphate group in phosphotyrosine peptides.

Journal: Biophysical journal20030201

Title: Invasion of retinal pigment epithelial cells: N-cadherin, hepatocyte growth factor, and focal adhesion kinase.

Journal: Investigative ophthalmology & visual science20030201

Title: Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20030201

Title: Effect of exogenously administered HGF activator in liver regeneration.

Journal: Transplantation proceedings20030201

Title: Involvement of linker for activation of T cells in the costimulatory signaling pathways.

Journal: Transplantation proceedings20030201

Title: The HIV protease inhibitor indinavir impairs glycogen synthesis in HepG2 hepatoma cells.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association20030201

Title: Kinetic and site-directed mutagenesis studies of prevotella intermedia acid phosphatase.

Journal: Protein and peptide letters20030201

Title: JAK/STAT but not ERK1/ERK2 pathway mediates interleukin (IL)-6/soluble IL-6R down-regulation of Type II collagen, aggrecan core, and link protein transcription in articular chondrocytes. Association with a down-regulation of SOX9 expression.

Journal: The Journal of biological chemistry20030131

Title: The requirement of specific membrane domains for Raf-1 phosphorylation and activation.

Journal: The Journal of biological chemistry20030131

Title: Platelet-endothelial cell adhesion molecule-1 modulates endothelial migration through its immunoreceptor tyrosine-based inhibitory motif.

Journal: Biochemical and biophysical research communications20030131

Title: Ezrin is a substrate for Lck in T cells.

Journal: FEBS letters20030130

Title: Macrocyclization in the design of Grb2 SH2 domain-binding ligands exhibiting high potency in whole-cell systems.

Journal: Journal of medicinal chemistry20030116

Title: A synthetic heparin-mimicking polyanionic compound inhibits central nervous system inflammation.

Journal: Journal of the neurological sciences20030115

Title: Effect of a novel somatostatin analogue combined with cytotoxic drugs on human tumour xenografts and metastasis of B16 melanoma.

Journal: British journal of cancer20030113

Title: Mutation of the protein tyrosine kinase consensus site in the herpes simplex virus 1 alpha22 gene alters ICP22 posttranslational modification.

Journal: Virology20030105

Title: Stromal cell-derived factor-1alpha induces tube-like structure formation of endothelial cells through phosphoinositide 3-kinase.

Journal: The Journal of biological chemistry20030103

Title: Protein kinase D mediates a stress-induced NF-kappaB activation and survival pathway.

Journal: The EMBO journal20030102

Title: Protein-tyrosine-phosphatase 1B activation is regulated developmentally in muscle of neonatal pigs.

Journal: American journal of physiology. Endocrinology and metabolism20030101

Title: Protein phosphatase-2A restricts migration of Lewis lung carcinoma cells by modulating the phosphorylation of focal adhesion proteins.

Journal: International journal of cancer20030101

Title: Receptor protein tyrosine phosphatases as mediators of cellular adhesion.

Journal: Frontiers in bioscience : a journal and virtual library20030101

Title: Porcine sperm capacitation and tyrosine kinase activity are dependent on bicarbonate and calcium but protein tyrosine phosphorylation is only associated with calcium.

Journal: Biology of reproduction20030101

Title: The combi-targeting concept: a novel 3,3-disubstituted nitrosourea with EGFR tyrosine kinase inhibitory properties.

Journal: Cancer chemotherapy and pharmacology20030101

Title: Subunit-specific modulation of KCNQ potassium channels by Src tyrosine kinase.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20030101

Title: H1-A extracted from Cordyceps sinensis suppresses the proliferation of human mesangial cells and promotes apoptosis, probably by inhibiting the tyrosine phosphorylation of Bcl-2 and Bcl-XL.

Journal: The Journal of laboratory and clinical medicine20030101

Title: HGF, MET, and matrix-related proteases in hepatocellular carcinoma, fibrolamellar variant, cirrhotic and normal liver.

Journal: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc20030101

Title: FLT3 mutations in acute myeloid leukemia cell lines.

Journal: Leukemia20030101

Title: Structural determinants of integrin recognition by talin.

Journal: Molecular cell20030101

Title: Simultaneous detection of ACP1 and GC genotypes using PCR/SSCP.

Journal: Annals of human genetics20030101

Title: The role of the ubiquitination-proteasome pathway in breast cancer: ubiquitin mediated degradation of growth factor receptors in the pathogenesis and treatment of cancer.

Journal: Breast cancer research : BCR20030101

Title: Isolation of novel substrates using a tyrosine kinase overlay/in situ assay.

Journal: Methods in molecular biology (Clifton, N.J.)20030101

Title: Assaying tyrosine phosphorylation of insulin receptor and insulin receptor substrates.

Journal: Methods in molecular medicine20030101

Title: Measuring insulin-stimulated phosphatidyl-inositol 3-kinase activity.

Journal: Methods in molecular medicine20030101

Title: [The role of tyrosine phosphorylation in the regulation of cell proliferation and differentiation in lower eukaryotes].

Journal: Tsitologiia20030101

Title: A novel Leishmania infantum nuclear phosphoprotein Lepp12 which stimulates IL1-beta synthesis in THP-1 transfectants.

Journal: BMC microbiology20030101

Title: Plasma levels of HER-2/neu, tumor type M2 pyruvate kinase and its tyrosine-phosphorylated metabolite in advanced breast cancer.

Journal: Anticancer research20030101

Title: The 35 kDa acid metallophosphatase of the frog Rana esculenta liver: studies on its cellular localization and protein phosphatase activity.

Journal: Acta biochimica Polonica20030101

Title: Protein phosphatase-2A regulates protein tyrosine phosphatase activity in Lewis lung carcinoma tumor variants.

Journal: Clinical & experimental metastasis20030101

Title: Adhesion of endothelial cells to NOV is mediated by the integrins alphavbeta3 and alpha5beta1.

Journal: Journal of vascular research20030101

Title: Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells.

Journal: BMC cancer20030101

Title: The influence of the extracellular matrix on the morphology and intracellular pH of cultured astrocytes exposed to media lacking bicarbonate.

Journal: Neuroscience20030101

Title: Role of gonadotropin-releasing hormone (GnRH) in ovarian cancer.

Journal: Reproductive biology and endocrinology : RB&E20030101

Title: Changes in sperm phosphotyrosine proteins by human follicular fluid in mice.

Journal: Archives of andrology20030101

Title: Gonadotropin releasing hormone analogue (GnRHa) alters the expression and activation of Smad in human endometrial epithelial and stromal cells.

Journal: Reproductive biology and endocrinology : RB&E20030101

Title: FK506 attenuates the post-ischemic perturbation of protein kinases and tyrosine phosphorylation in the gerbil hippocampal CA1 sectors.

Journal: Acta neurochirurgica. Supplement20030101

Title: Structure-based design of novel nonpeptide inhibitors of the Src SH2 domain:phosphotyrosine mimetics exploiting multifunctional group replacement chemistry.

Journal: Biopolymers20030101

Title: Inhibition of lactate dehydrogenase C4 (LDH-C4) blocks capacitation of mouse sperm in vitro.

Journal: Cytogenetic and genome research20030101

Title: T cell receptor-mediated signalling in T cells from multiple myeloma patients.

Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology20030101

Title: Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle.

Journal: The Journal of biological chemistry20021227

Title: Protein kinase C delta associates with the interleukin-6 receptor subunit glycoprotein (gp) 130 via Stat3 and enhances Stat3-gp130 interaction.

Journal: The Journal of biological chemistry20021220

Title: Phosphoinositide binding by the pleckstrin homology domains of Ipl and Tih1.

Journal: The Journal of biological chemistry20021220

Title: Lyn and Syk kinases are sequentially engaged in phagocytosis mediated by Fc gamma R.

Journal: Journal of immunology (Baltimore, Md. : 1950)20021215

Title: Autocrine activation of the hepatocyte growth factor receptor/met tyrosine kinase induces tumor cell motility by regulating pseudopodial protrusion.

Journal: The Journal of biological chemistry20021213

Title: Design and use of a mammalian protein-protein interaction trap (MAPPIT).

Journal: Science's STKE : signal transduction knowledge environment20021210

Title: Crystal structure and NMR studies of the apo SH2 domains of ZAP-70: two bikes rather than a tandem.

Journal: Biochemistry20021203

Title: Internalization of inactive EGF receptor into endosomes and the subsequent activation of endosome-associated EGF receptors. Epidermal growth factor.

Journal: Science's STKE : signal transduction knowledge environment20021203

Title: Design and synthesis of a beta-amino phosphotyrosyl mimetic suitably protected for peptide synthesis.

Journal: Bioorganic & medicinal chemistry letters20021202

Title: Lipopolysaccharide-induced reductions in cellular coupling correlate with tyrosine phosphorylation of connexin 43.

Journal: Journal of cellular physiology20021201

Title: Mechanism by which cAMP activates PI3-kinase and increases bile acid secretion in WIF-B9 cells.

Journal: American journal of physiology. Cell physiology20021201

Title: Restoration of synapse formation in Musk mutant mice expressing a Musk/Trk chimeric receptor.

Journal: Development (Cambridge, England)20021201

Title: Stimulated tyrosine phosphorylation of phosphatidylinositol 3-kinase causes acidic pH-induced contraction in spontaneously hypertensive rat aorta.

Journal: The Journal of pharmacology and experimental therapeutics20021201

Title: A role for Grb2-associated binder-1 in growth hormone signaling.

Journal: Endocrinology20021201

Title: Expression patterns of focal adhesion associated proteins in the developing retina.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists20021201

Title: Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development.

Journal: Molecular endocrinology (Baltimore, Md.)20021201

Title: Dual mechanism of signal transducer and activator of transcription 5 activation by the insulin receptor.

Journal: Molecular endocrinology (Baltimore, Md.)20021201

Title: Characterization of morphological and cytoskeletal changes in trophoblast cells induced by insulin-like growth factor-I.

Journal: The Journal of clinical endocrinology and metabolism20021201

Title: IgG-mediated signal transduction in canine mastocytoma-derived cells.

Journal: International archives of allergy and immunology20021201

Title: Cellular signaling during the macrophage invasion by Trypanosoma cruzi.

Journal: Histochemistry and cell biology20021201

Title: EDTA inhibits collagen-induced ATP+ADP secretion and tyrosine phosphorylation in platelets independently of Mg2+ chelation and decrease in pH.

Journal: Platelets20021201

Title: Absence of functional insulin receptor substrate-3 (IRS-3) gene in humans.

Journal: Diabetologia20021201

Title: Lyn kinase is activated following thrombopoietin stimulation of the megakaryocytic cell line B1647.

Journal: Haematologica20021201

Title: Tyrosine kinase activity of nerve growth factor and estrogen in embryonic septal neurons cultured from the rat.

Journal: Neurochemical research20021201

Title: Convulsive disorder and the genetics of signal transduction; a study of a low molecular weight protein tyrosine phosphatase in a pediatric sample.

Journal: Neuroscience letters20021129

Title: SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells.

Journal: Cytokine20021124

Title: Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis.

Journal: Oncogene20021121

Title: The roles of phosphotyrosines-294, -404, and -451 in RET/PTC1-induced thyroid tumor formation.

Journal: Oncogene20021121

Title: Ca2+ promotes erythrocyte band 3 tyrosine phosphorylation via dissociation of phosphotyrosine phosphatase from band 3.

Journal: The Biochemical journal20021115

Title: ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2.

Journal: The Journal of biological chemistry20021115

Title: PACAP-27 tyrosine phosphorylates mitogen activated protein kinase and increases VEGF mRNAs in human lung cancer cells.

Journal: Regulatory peptides20021115

Title: Cloning of a novel phosphotyrosine binding domain containing molecule, Odin, involved in signaling by receptor tyrosine kinases.

Journal: Oncogene20021114

Title: In vivo regulation of phosphoinositide 3-kinase in retina through light-induced tyrosine phosphorylation of the insulin receptor beta-subunit.

Journal: The Journal of biological chemistry20021108

Title: Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras.

Journal: The Journal of biological chemistry20021108

Title: Identification and characterization of two novel low-molecular-weight dual specificity phosphatases.

Journal: Biochemical and biophysical research communications20021108

Title: Elevated c-Src is linked to altered cell-matrix adhesion rather than proliferation in KM12C human colorectal cancer cells.

Journal: British journal of cancer20021104

Title: Low Mr phosphotyrosine protein phosphatase associates and dephosphorylates p125 focal adhesion kinase, interfering with cell motility and spreading.

Journal: The Journal of biological chemistry20021101

Title: Valosine containing protein is a substrate of cAMP-activated boar sperm tyrosine kinase.

Journal: Molecular reproduction and development20021101

Title: Redistribution of ERK/MAP kinase to uropod-like structures in interleukin-3-induced cell shape changes.

Journal: Immunology letters20021101

Title: Characterization of an ecto-phosphatase activity in the human parasite Trichomonas vaginalis.

Journal: Parasitology research20021101

Title: Evolution of catalytic antibody repertoire in autoimmune mice.

Journal: Journal of immunological methods20021101

Title: The Src homology 2 domain-containing inositol 5-phosphatase negatively regulates Fcgamma receptor-mediated phagocytosis through immunoreceptor tyrosine-based activation motif-bearing phagocytic receptors.

Journal: Blood20021101

Title: A new and recurrent activating length mutation in exon 20 of the FLT3 gene in acute myeloid leukemia.

Journal: Blood20021101

Title: Insulin stimulates spreading of skeletal muscle cells involving the activation of focal adhesion kinase, phosphatidylinositol 3-kinase and extracellular signal regulated kinases.

Journal: Journal of cellular physiology20021101

Title: Imaging antigen-induced PI3K activation in T cells.

Journal: Nature immunology20021101

Title: Regulation of the phosphotyrosine content of human sperm proteins by intracellular Ca2+: role of Ca2+-adenosine triphosphatases.

Journal: Biology of reproduction20021101

Title: The increased bone mass in deltaFosB transgenic mice is independent of circulating leptin levels.

Journal: Endocrinology20021101

Title: Comparative proteome bioinformatics: identification of a whole complement of putative protein tyrosine kinases in the model flowering plant Arabidopsis thaliana.

Journal: Proteomics20021101

Title: Characterization of YM-90709 as a novel antagonist which inhibits the binding of interleukin-5 to interleukin-5 receptor.

Journal: International immunopharmacology20021101

Title: [Changes of protein tyrosine phosphorylation in erythrocyte band 3 glucose-6-phosphate dehydrogenase deficiency].

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi20021101

Title: Signal transduction through tyrosine-phosphorylated carboxy-terminal fragments of APP via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain.

Journal: Annals of the New York Academy of Sciences20021101

Title: Secretory activity of boar seminal vesicle glands.

Journal: Reproductive biology20021101

Title: Production of antibodies that recognize specific tyrosine-phosphorylated peptides.

Journal: Current protocols in immunology20021101

Title: Substrate conformational restriction and CD45-catalyzed dephosphorylation of tail tyrosine-phosphorylated Src protein.

Journal: The Journal of biological chemistry20021025

Title: Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces specific phosphorylation of ErbB2 and enhances expression of p27(kip), but does not activate mitogen-activated kinase or protein kinaseB/Akt pathways.

Journal: Oncogene20021024

Title: Chicken anemia virus VP2 is a novel dual specificity protein phosphatase.

Journal: The Journal of biological chemistry20021018

Title: Regulation of the EphA2 kinase by the low molecular weight tyrosine phosphatase induces transformation.

Journal: The Journal of biological chemistry20021018

Title: The N-terminal SH2 domains of Syk and ZAP-70 mediate phosphotyrosine-independent binding to integrin beta cytoplasmic domains.

Journal: The Journal of biological chemistry20021018

Title: Capacitation-like alterations in cooled boar spermatozoa: assessment by the chlortetracycline staining assay and immunodetection of tyrosine-phosphorylated sperm proteins.

Journal: Animal reproduction science20021016

Title: Analysis of tyrosine phosphorylation sites in signaling molecules by a phosphotyrosine-specific immonium ion scanning method.

Journal: Science's STKE : signal transduction knowledge environment20021015

Title: Negative regulation of urokinase-type plasminogen activator production through FGF-2-mediated activation of phosphoinositide 3-kinase.

Journal: Oncogene20021010

Title: Design and characterization of non-phosphopeptide inhibitors for Src family SH2 domains.

Journal: Bioorganic & medicinal chemistry letters20021007

Title: Development of a phosphatase-stable phosphotyrosyl mimetic suitably protected for the synthesis of high-affinity Grb2 SH2 domain-binding ligands.

Journal: Bioorganic & medicinal chemistry letters20021007

Title: Altered biological activity associated with C-terminal modifications of IL-7.

Journal: Cytokine20021007

Title: Insight into the role of low molecular weight phosphotyrosine phosphatase (LMW-PTP) on platelet-derived growth factor receptor (PDGF-r) signaling. LMW-PTP controls PDGF-r kinase activity through TYR-857 dephosphorylation.

Journal: The Journal of biological chemistry20021004

Title: Secretin regulates paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway.

Journal: American journal of physiology. Gastrointestinal and liver physiology20021001

Title: Interferon-gamma activates EGF receptor and increases TGF-alpha in T84 cells: implications for chloride secretion.

Journal: American journal of physiology. Gastrointestinal and liver physiology20021001

Title: The SPOT technique as a tool for studying protein tyrosine phosphatase substrate specificities.

Journal: Protein science : a publication of the Protein Society20021001

Title: Myelin proteolipid protein, basic protein, the small isoform of myelin-associated glycoprotein, and p42MAPK are associated in the Triton X-100 extract of central nervous system myelin.

Journal: Journal of neuroscience research20021001

Title: Soy isoflavone genistein modulates cell cycle progression and induces apoptosis in HER-2/neu oncogene expressing human breast epithelial cells.

Journal: International journal of oncology20021001

Title: IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response.

Journal: Journal of immunology (Baltimore, Md. : 1950)20021001

Title: c-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitination.

Journal: Journal of immunology (Baltimore, Md. : 1950)20021001

Title: Staging and resetting T cell activation in SMACs.

Journal: Nature immunology20021001

Title: Probing Src homology 2 domain ligand interactions by differential line broadening.

Journal: Biochemistry20021001

Title: Two distinct phosphoinositide 3-kinases mediate polypeptide growth factor-stimulated PKB activation.

Journal: The EMBO journal20021001

Title: A tumor suppressor homolog, AtPTEN1, is essential for pollen development in Arabidopsis.

Journal: The Plant cell20021001

Title: SRC homology-2 inhibitors: peptidomimetic and nonpeptide.

Journal: Mini reviews in medicinal chemistry20021001

Title: Development of a time-resolved fluorescent assay for measuring tyrosine-phosphorylated proteins in cells.

Journal: Analytical biochemistry20021001

Title: Transforming growth factor-beta(1) augments granulocyte-macrophage colony-stimulating factor-induced proliferation of umbilical cord blood CD34(+) cells with an associated tyrosine phosphorylation of STAT5.

Journal: Experimental hematology20021001

Title: Molecular mechanism involved in matrix dependent upregulation of matrix metalloproteinases in monocyte/macrophage.

Journal: Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB)20021001

Title: The docking protein FRS2alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors.

Journal: Molecular cell20021001

Title: Grb2 is a key mediator of helicobacter pylori CagA protein activities.

Journal: Molecular cell20021001

Title: Arsenate reductases in prokaryotes and eukaryotes.

Journal: Environmental health perspectives20021001

Title: Expression of epidermal growth factor receptor and related phosphorylation proteins in hypertrophic scars and normal skin.

Journal: Chinese medical journal20021001

Title: Inhibition of bovine kidney low molecular mass phosphotyrosine protein phosphatase by uric acid.

Journal: Journal of enzyme inhibition and medicinal chemistry20021001

Title: SHP1 protein-tyrosine phosphatase regulates HoxA10 DNA binding and transcriptional repression activity in undifferentiated myeloid cells.

Journal: The Journal of biological chemistry20020927

Title: Side-chain dynamics of the SAP SH2 domain correlate with a binding hot spot and a region with conformational plasticity.

Journal: Journal of molecular biology20020920

Title: Tyrosine phosphorylation of clathrin heavy chain under oxidative stress.

Journal: Biochemical and biophysical research communications20020920

Title: PrpE, a PPP protein phosphatase from Bacillus subtilis with unusual substrate specificity.

Journal: The Biochemical journal20020915

Title: Peroxynitrite signaling: receptor tyrosine kinases and activation of stress-responsive pathways.

Journal: Free radical biology & medicine20020915

Title: Regulation of phosphatidylinositol 3-kinase activity and phosphatidylinositol 3,4,5-trisphosphate accumulation by neutrophil priming agents.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020915

Title: Sck is expressed in endothelial cells and participates in vascular endothelial growth factor-induced signaling.

Journal: Oncogene20020912

Title: Antagonistic and agonistic effects of quinazoline tyrosine kinase inhibitors on mutant EGF receptor function.

Journal: International journal of cancer20020910

Title: CD4 is active as a signaling molecule on the human monocytic cell line Thp-1.

Journal: Experimental cell research20020910

Title: Enumeration, phenotyping, and identification of activation events in conjugates between T cells and antigen-presenting cells by flow cytometry.

Journal: Science's STKE : signal transduction knowledge environment20020910

Title: Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc.

Journal: British journal of cancer20020909

Title: Oxidant-induced vascular endothelial growth factor expression in human keratinocytes and cutaneous wound healing.

Journal: The Journal of biological chemistry20020906

Title: Nitration of PECAM-1 ITIM tyrosines abrogates phosphorylation and SHP-2 binding.

Journal: Biochemical and biophysical research communications20020906

Title: Proteasome inhibitors regulate tyrosine phosphorylation of IRS-1 and insulin signaling in adipocytes.

Journal: Biochemical and biophysical research communications20020906

Title: Nitric oxide-induced motility in aortic smooth muscle cells: role of protein tyrosine phosphatase SHP-2 and GTP-binding protein Rho.

Journal: Circulation research20020906

Title: Stimulation of hepatic signal transducer and activator of transcription 5b by GH is not altered by 3-methylcholanthrene.

Journal: Endocrinology20020901

Title: c-Cbl is a negative regulator of GH-stimulated STAT5-mediated transcription.

Journal: Endocrinology20020901

Title: Differential expression of multiple isoforms of the ELKS mRNAs involved in a papillary thyroid carcinoma.

Journal: Genes, chromosomes & cancer20020901

Title: Suppression of IL-4- and CD40-induced B-lymphocyte activation by intravenous immunoglobulin is not mediated through the inhibitory IgG receptor FcgammaRIIb.

Journal: The Journal of allergy and clinical immunology20020901

Title: Novel peptide inhibitors for Grb2 SH2 domain and their detection by surface plasmon resonance.

Journal: The journal of peptide research : official journal of the American Peptide Society20020901

Title: pp60(c-src) is a negative regulator of laminin-1-mediated neurite outgrowth in chick sensory neurons.

Journal: Molecular and cellular neurosciences20020901

Title: Regulation and targets of receptor tyrosine kinases.

Journal: European journal of cancer (Oxford, England : 1990)20020901

Title: Involvement of cell-cell interactions in the rapid stimulation of Cas tyrosine phosphorylation and Src kinase activity by transforming growth factor-beta 1.

Journal: The Journal of biological chemistry20020830

Title: Regulation of signaling in B cells through the phosphorylation of Syk on linker region tyrosines. A mechanism for negative signaling by the Lyn tyrosine kinase.

Journal: The Journal of biological chemistry20020830

Title: Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines.

Journal: Oncogene20020829

Title: Density functional study of the mechanism of a tyrosine phosphatase: I. Intermediate formation.

Journal: Journal of the American Chemical Society20020828

Title: Signal transduction through the T cell receptor is dynamically regulated by balancing kinase and phosphatase activities.

Journal: Biochemical and biophysical research communications20020823

Title: The SH3 domain of Src can downregulate its kinase activity in the absence of the SH2 domain-pY527 interaction.

Journal: Biochemical and biophysical research communications20020823

Title: General method for the synthesis of caged phosphopeptides: tools for the exploration of signal transduction pathways.

Journal: Organic letters20020822

Title: Antibody-based fluorescence detection of kinase activity on a peptide array.

Journal: Bioorganic & medicinal chemistry letters20020819

Title: Rational design of 4,5-disubstituted-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-ones as a novel class of inhibitors of epidermal growth factor receptor (EGF-R) and Her2(p185(erbB)) tyrosine kinases.

Journal: Bioorganic & medicinal chemistry letters20020819

Title: Phosphotyrosine-specific phosphatase PTP-SL regulates the ERK5 signaling pathway.

Journal: The Journal of biological chemistry20020816

Title: Functional interleukin-7 receptors (IL-7Rs) are expressed by marrow stromal cells: binding of IL-7 increases levels of IL-6 mRNA and secreted protein.

Journal: Blood20020815

Title: TEL-JAK2 constitutively activates the extracellular signal-regulated kinase (ERK), stress-activated protein/Jun kinase (SAPK/JNK), and p38 signaling pathways.

Journal: Blood20020815

Title: Constitutive activation of Jak/STAT proteins in Epstein-Barr virus-infected B-cell lines from patients with posttransplant lymphoproliferative disorder.

Journal: Transplantation20020815

Title: Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking.

Journal: Biochemistry20020813

Title: Intramolecular quenching of tryptophan fluorescence by the peptide bond in cyclic hexapeptides.

Journal: Journal of the American Chemical Society20020807

Title: The Src-cortactin pathway is required for clustering of E-selectin and ICAM-1 in endothelial cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20020801

Title: SH3 domain-mediated binding of the Drk protein to Dos is an important step in signaling of Drosophila receptor tyrosine kinases.

Journal: Mechanisms of development20020801

Title: Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020801

Title: Phosphotyrosine - a novel marker for H1 horizontal cells in normal human retinas.

Journal: Experimental eye research20020801

Title: Potentiation of insulin signaling in tissues of Zucker obese rats after acute and long-term treatment with PPARgamma agonists.

Journal: Diabetes20020801

Title: Laminin alpha5 chain adhesion and signaling in conjunctival epithelial cells.

Journal: Investigative ophthalmology & visual science20020801

Title: Phosphorylation of Hrs downstream of the epidermal growth factor receptor.

Journal: European journal of biochemistry20020801

Title: Expression of junction-associated proteins differentiates mouse intestinal M cells from enterocytes.

Journal: Histochemistry and cell biology20020801

Title: Phosphorylation by protein kinase CK2: a signaling switch for the caspase-inhibiting protein ARC.

Journal: Molecular cell20020801

Title: Comparison of red wine extract and polyphenol constituents on endothelin-1 synthesis by cultured endothelial cells.

Journal: Clinical science (London, England : 1979)20020801

Title: Tyrosine phosphorylation of the metabotropic glutamate receptor mGluR5 in striatal neurons.

Journal: Neuropharmacology20020801

Title: Probing the phosphopeptide specificities of protein tyrosine phosphatases, SH2 and PTB domains with combinatorial library methods.

Journal: Current protein & peptide science20020801

Title: Structural basis for inhibition of protein tyrosine phosphatases by Keggin compounds phosphomolybdate and phosphotungstate.

Journal: Experimental & molecular medicine20020731

Title: Structural requirements for interaction of sodium channel beta 1 subunits with ankyrin.

Journal: The Journal of biological chemistry20020719

Title: Mediation of the DCC apoptotic signal by DIP13 alpha.

Journal: The Journal of biological chemistry20020719

Title: Mitogen-induced, FAK-dependent tyrosine phosphorylation of the SSeCKS scaffolding protein.

Journal: Experimental cell research20020715

Title: Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord during the development and maintenance of inflammatory hyperalgesia.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20020715

Title: Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP.

Journal: Biochemical and biophysical research communications20020712

Title: Tk-PTP, protein tyrosine/serine phosphatase from hyperthermophilic archaeon Thermococcus kodakaraensis KOD1: enzymatic characteristics and identification of its substrate proteins.

Journal: Biochemical and biophysical research communications20020712

Title: The common gamma chain (gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3.

Journal: Biochemistry20020709

Title: Activation of ZAP-70 through specific dephosphorylation at the inhibitory Tyr-292 by the low molecular weight phosphotyrosine phosphatase (LMPTP).

Journal: The Journal of biological chemistry20020705

Title: Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420.

Journal: The Journal of biological chemistry20020705

Title: Src-dependent phosphorylation of the epidermal growth factor receptor on tyrosine 845 is required for zinc-induced Ras activation.

Journal: The Journal of biological chemistry20020705

Title: The lipid peroxidation product 4-hydroxynonenal facilitates opening of voltage-dependent Ca2+ channels in neurons by increasing protein tyrosine phosphorylation.

Journal: The Journal of biological chemistry20020705

Title: Determination of active concentrations and association and dissociation rate constants of interacting biomolecules: an analytical solution to the theory for kinetic and mass transport limitations in biosensor technology and its experimental verification.

Journal: Biochemistry20020702

Title: Cellular signalling in arteriolar myogenic constriction: involvement of tyrosine phosphorylation pathways.

Journal: Clinical and experimental pharmacology & physiology20020701

Title: Endothelin-induced myoplasmic Ca2+ responses and tyrosine phosphorylation in coronary smooth muscle.

Journal: Journal of cardiovascular pharmacology20020701

Title: PTEN is a negative regulator of STAT3 activation in human papillomavirus-infected cells.

Journal: The Journal of general virology20020701

Title: Regulation of the human sperm tyrosine kinase c-yes. Activation by cyclic adenosine 3',5'-monophosphate and inhibition by Ca(2+).

Journal: Biology of reproduction20020701

Title: Localisation of somatostatin and somatostatin receptors in benign and malignant ovarian tumours.

Journal: British journal of cancer20020701

Title: G(1)/S CDK is inhibited to restrain mitotic onset when DNA replication is blocked in fission yeast.

Journal: The EMBO journal20020701

Title: SRC-1 and Wnt signaling act together to specify endoderm and to control cleavage orientation in early C. elegans embryos.

Journal: Developmental cell20020701

Title: Juvenile hormone stimulated tyrosine kinase-mediated protein phosphorylation in the CNS of the silk worm, Bombyx mori.

Journal: Archives of insect biochemistry and physiology20020701

Title: A new type of antimetastatic peptide derived from fibronectin.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20020701

Title: Expression and functional analysis of the anaplastic lymphoma kinase (ALK) gene in tumor cell lines.

Journal: International journal of cancer20020701

Title: NO attenuates insulin signaling and motility in aortic smooth muscle cells via protein tyrosine phosphatase 1B-mediated mechanism.

Journal: Arteriosclerosis, thrombosis, and vascular biology20020701

Title: Subproteomics analysis of phosphorylated proteins: application to the study of B-lymphoblasts from a patient with Scott syndrome.

Journal: Proteomics20020701

Title: Hypothermic reperfusion after cardiac arrest augments brain-derived neurotrophic factor activation.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism20020701

Title: A novel precursor ion discovery method on a hybrid quadrupole orthogonal acceleration time-of-flight (Q-TOF) mass spectrometer for studying protein phosphorylation.

Journal: Journal of the American Society for Mass Spectrometry20020701

Title: Dynamic characterization of the molecular events during in vitro epidermal wound healing.

Journal: The Journal of investigative dermatology20020701

Title: A mass spectrometry-based proteomic approach for identification of serine/threonine-phosphorylated proteins by enrichment with phospho-specific antibodies: identification of a novel protein, Frigg, as a protein kinase A substrate.

Journal: Molecular & cellular proteomics : MCP20020701

Title: Proteomic analysis of protein phosphorylations in heat shock response and thermotolerance.

Journal: The Journal of biological chemistry20020628

Title: Thrombin-stimulated Pyk2 phosphorylation in human endothelium is dependent on intracellular calcium and independent of protein kinase C and Src kinases.

Journal: Biochemical and biophysical research communications20020628

Title: G120K-PEG, a human GH antagonist, decreases GH signal transduction in the liver of mice.

Journal: Molecular and cellular endocrinology20020628

Title: Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation.

Journal: Cell20020628

Title: Transformation of Ba/F3 cells and Rat-1 cells by ETV6/ARG.

Journal: Oncogene20020627

Title: Phosphorylated tyrosine-containing proteins in primary lung cancer correlates with proliferation and prognosis.

Journal: British journal of cancer20020617

Title: Differential role of glycolipid-enriched membrane domains in glycoprotein VI- and integrin-mediated phospholipase Cgamma2 regulation in platelets.

Journal: The Biochemical journal20020615

Title: Comparative expression profiles of Trk receptors and Shc-related phosphotyrosine adapters during retinal development: potential roles of N-Shc/ShcC in brain-derived neurotrophic factor signal transduction and modulation.

Journal: Journal of neuroscience research20020615

Title: Mitotic activation of protein-tyrosine phosphatase alpha and regulation of its Src-mediated transforming activity by its sites of protein kinase C phosphorylation.

Journal: The Journal of biological chemistry20020614

Title: The phosphotyrosine binding-like domain of talin activates integrins.

Journal: The Journal of biological chemistry20020614

Title: SAR and X-ray. A new approach combining fragment-based screening and rational drug design: application to the discovery of nanomolar inhibitors of Src SH2.

Journal: Journal of medicinal chemistry20020606

Title: First artificial receptors and chemosensors toward phosphorylated peptide in aqueous solution.

Journal: Journal of the American Chemical Society20020605

Title: Clustering the mast cell function-associated antigen (MAFA) leads to tyrosine phosphorylation of p62Dok and SHIP and affects RBL-2H3 cell cycle.

Journal: Immunology letters20020603

Title: Receptor tyrosine phosphatase, CD45 binds galectin-1 but does not mediate its apoptotic signal in T cell lines.

Journal: Immunology letters20020603

Title: Different proteins are phosphorylated under acidic environments in Jurkat cells.

Journal: Immunology letters20020603

Title: Effect of hyperglycemia on the basal cytosolic free calcium level, calcium signal and tyrosine-phosphorylation in human T-cells.

Journal: Immunology letters20020603

Title: Developmental differences in B cell receptor-induced signal transduction.

Journal: Cellular signalling20020601

Title: Focal adhesion kinase tyrosine phosphorylation is associated with myogenesis and modulated by insulin.

Journal: Cell proliferation20020601

Title: Phosphotyrosine proteins in platelets from patients with storage pool disease: direct relation between granule defects and defective signal transduction.

Journal: Haematologica20020601

Title: Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and glucokinase genes in rat hepatocytes.

Journal: Diabetes20020601

Title: Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans.

Journal: Diabetes20020601

Title: Female rats do not exhibit free fatty acid-induced insulin resistance.

Journal: Diabetes20020601

Title: Differential effects of tumor necrosis factor-alpha on protein kinase C isoforms alpha and delta mediate inhibition of insulin receptor signaling.

Journal: Diabetes20020601

Title: Ganglioside GM3 activates ERKs in human lymphocytic cells.

Journal: Journal of lipid research20020601

Title: Rho and basic fibroblast growth factor involvement in centrosome redistribution and actin microfilament remodeling during early endothelial wound repair.

Journal: Journal of vascular surgery20020601

Title: Expression and characterization of the Drosophila X11-like/Mint protein during neural development.

Journal: Journal of neurochemistry20020601

Title: Altered arachidonic acid biosynthesis and antioxidant protection mechanisms in Schwann cells grown in elevated glucose.

Journal: Journal of neurochemistry20020601

Title: Phosphorylation of the movement protein of cucumber mosaic virus in transgenic tobacco plants.

Journal: Virus genes20020601

Title: Identification of the phosphotyrosine proteome from thrombin activated platelets.

Journal: Proteomics20020601

Title: Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation.

Journal: Immunity20020601

Title: Basic fibroblast growth factor: effects on matrix remodeling, receptor expression, and transduction pathway in human periosteal fibroblasts with FGFR2 gene mutation.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research20020601

Title: Regulation of IRS-1/SHP2 interaction and AKT phosphorylation in animal models of insulin resistance.

Journal: Endocrine20020601

Title: Tyrosine phosphatase CD45 regulates hydrogen peroxide-induced calcium mobilization in B cells.

Journal: Antioxidants & redox signaling20020601

Title: Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade.

Journal: The Journal of biological chemistry20020531

Title: Insulin-like growth factor-binding protein-3 activates a phosphotyrosine phosphatase. Effects on the insulin-like growth factor signaling pathway.

Journal: The Journal of biological chemistry20020531

Title: Phosphatidylinositol 3-kinase is required for insulin-stimulated tyrosine phosphorylation of Shc in 3T3-L1 adipocytes.

Journal: The Journal of biological chemistry20020524

Title: Amyloid precursor protein processing is separately regulated by protein kinase C and tyrosine kinase in human astrocytes.

Journal: Neuroscience letters20020524

Title: Molecular docking and high-throughput screening for novel inhibitors of protein tyrosine phosphatase-1B.

Journal: Journal of medicinal chemistry20020523

Title: Opposite effects of different doses of MCSF on ERK phosphorylation and cell proliferation in macrophages.

Journal: Oncogene20020523

Title: Phosphoinositide 3-kinases in lysophosphatidic acid signaling: regulation and cross-talk with the Ras/mitogen-activated protein kinase pathway.

Journal: Biochimica et biophysica acta20020523

Title: Plasma membrane phospholipid scramblase 1 is enriched in lipid rafts and interacts with the epidermal growth factor receptor.

Journal: Biochemistry20020521

Title: Drac1 and Crumbs participate in amnioserosa morphogenesis during dorsal closure in Drosophila.

Journal: Journal of cell science20020515

Title: New perspectives in PDGF receptor downregulation: the main role of phosphotyrosine phosphatases.

Journal: Journal of cell science20020515

Title: SHP-1- and phosphotyrosine-independent inhibitory signaling by a killer cell Ig-like receptor cytoplasmic domain in human NK cells.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020515

Title: Localized exocytosis of primary (lysosomal) granules during phagocytosis: role of Ca2+-dependent tyrosine phosphorylation and microtubules.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020515

Title: Labeling of antibodies by in situ modification of thiol groups generated from selenol-catalyzed reduction of native disulfide bonds.

Journal: Analytical biochemistry20020515

Title: Cleavage properties of an archaeal site-specific recombinase, the SSV1 integrase.

Journal: The Journal of biological chemistry20020510

Title: FRS2 PTB domain conformation regulates interactions with divergent neurotrophic receptors.

Journal: The Journal of biological chemistry20020510

Title: Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc.

Journal: The Journal of biological chemistry20020510

Title: E-selectin modulates the malignant properties of T84 colon carcinoma cells.

Journal: Biochemical and biophysical research communications20020510

Title: Discovery of highly potent Src SH2 binders: structure-activity studies and X-ray structures.

Journal: Bioorganic & medicinal chemistry letters20020506

Title: Small ligands interacting with the phosphotyrosine binding pocket of the Src SH2 protein.

Journal: Bioorganic & medicinal chemistry letters20020506

Title: Protein mapping in rat basophilic leukaemia cells.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20020505

Title: Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation.

Journal: The Journal of biological chemistry20020503

Title: Platelet-derived growth factor (PDGF)-induced tyrosine phosphorylation of the low density lipoprotein receptor-related protein (LRP). Evidence for integrated co-receptor function betwenn LRP and the PDGF.

Journal: The Journal of biological chemistry20020503

Title: Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolae.

Journal: The Journal of biological chemistry20020503

Title: Experimental and calculated shift in pK(a) upon binding of phosphotyrosine peptide to the SH2 domain of p56(lck).

Journal: Bioorganic & medicinal chemistry20020501

Title: Ammonia induces MK-801-sensitive nitration and phosphorylation of protein tyrosine residues in rat astrocytes.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20020501

Title: Cr supplementation decreases tyrosine phosphorylation of the CreaT in skeletal muscle during sepsis.

Journal: American journal of physiology. Endocrinology and metabolism20020501

Title: Lymphocyte binding to MAdCAM-1 via alpha4beta7 integrin activates a signal transduction pathway involving tyrosine phosphorylation of paxillin and p105(Cas-L).

Journal: Immunology letters20020501

Title: Adrenocorticotropin/cyclic adenosine 3',5'-monophosphate-mediated transcription of the human CYP17 gene in the adrenal cortex is dependent on phosphatase activity.

Journal: Endocrinology20020501

Title: CTLA-4 suppresses proximal TCR signaling in resting human CD4(+) T cells by inhibiting ZAP-70 Tyr(319) phosphorylation: a potential role for tyrosine phosphatases.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020501

Title: Downstream of kinase, p62(dok), is a mediator of Fc gamma IIB inhibition of Fc epsilon RI signaling.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020501

Title: Stat5B shuttles between cytoplasm and nucleus in a cytokine-dependent and -independent manner.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020501

Title: The adapter molecule Gab2 regulates Fc epsilon RI-mediated signal transduction in mast cells.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020501

Title: SH3-dependent stimulation of Src-family kinase autophosphorylation without tail release from the SH2 domain in vivo.

Journal: Nature structural biology20020501

Title: Advanced glycation end product precursors impair epidermal growth factor receptor signaling.

Journal: Diabetes20020501

Title: Heterologous expression and catalytic properties of the C-terminal domain of starfish cdc25 dual-specificity phosphatase, a cell cycle regulator.

Journal: Journal of biochemistry20020501

Title: Persistent defect in transmitter release and synapsin phosphorylation in cerebral cortex after transient moderate ischemic injury.

Journal: Stroke20020501

Title: Expression of c-kit protein in proliferative lesions of human breast: sexual difference and close association with phosphotyrosine status.

Journal: Journal of cancer research and clinical oncology20020501

Title: A rapid extraction procedure of human hair proteins and identification of phosphorylated species.

Journal: Biological & pharmaceutical bulletin20020501

Title: Methods of analysis for chemicals that promote/disrupt cellular signaling.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry20020501

Title: Expression and localization of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.

Journal: Research in microbiology20020501

Title: Retinoic acid-induced growth arrest and differentiation: retinoic acid up-regulates CD32 (Fc gammaRII) expression, the ectopic expression of which retards the cell cycle.

Journal: Molecular cancer therapeutics20020501

Title: c-Cbl associates directly with the C-terminal tail of the receptor for the macrophage colony-stimulating factor, c-Fms, and down-modulates this receptor but not the viral oncogene v-Fms.

Journal: The Journal of biological chemistry20020426

Title: The fate of biodegradable microspheres injected into rat brain.

Journal: Neuroscience letters20020426

Title: Investigation of potential bioisosteric replacements for the carboxyl groups of peptidomimetic inhibitors of protein tyrosine phosphatase 1B: identification of a tetrazole-containing inhibitor with cellular activity.

Journal: Journal of medicinal chemistry20020425

Title: Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling.

Journal: The Journal of biological chemistry20020419

Title: Local actin polymerization and dynamin recruitment in SV40-induced internalization of caveolae.

Journal: Science (New York, N.Y.)20020419

Title: Repair by Src kinase of function-impaired RET with multiple endocrine neoplasia type 2A mutation with substitutions of tyrosines in the COOH-terminal kinase domain for phenylalanine.

Journal: Cancer research20020415

Title: STAT3 deficiency in keratinocytes leads to compromised cell migration through hyperphosphorylation of p130(cas).

Journal: The Journal of biological chemistry20020412

Title: Dominant negative knockout of p53 abolishes ErbB2-dependent apoptosis and permits growth acceleration in human breast cancer cells.

Journal: British journal of cancer20020408

Title: Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP).

Journal: The Journal of biological chemistry20020405

Title: Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathway.

Journal: The Journal of biological chemistry20020405

Title: Motif analysis of the tumor suppressor gene MMAC/PTEN identifies tyrosines critical for tumor suppression and lipid phosphatase activity.

Journal: Oncogene20020404

Title: Characterization and location of Src-dependent tyrosine phosphorylation in rat brain mitochondria.

Journal: Biochimica et biophysica acta20020403

Title: Differential involvement of Src family kinases in pervanadate-mediated responses in rat myometrial cells.

Journal: Cellular signalling20020401

Title: Decrease in growth factor receptors after treatment with serine protease inhibitor ONO-3403.

Journal: International journal of oncology20020401

Title: Human CD38 and CD16 are functionally dependent and physically associated in natural killer cells.

Journal: Blood20020401

Title: Protein tyrosine phosphorylation in T cell signaling.

Journal: Frontiers in bioscience : a journal and virtual library20020401

Title: Soluble fibrinogen modulates neutrophil functionality through the activation of an extracellular signal-regulated kinase-dependent pathway.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020401

Title: Inhibitors of receptor tyrosine kinases do not suppress progesterone-induced [Ca2+]i signalling in human spermatozoa.

Journal: Molecular human reproduction20020401

Title: Insulin resistance, defective insulin receptor substrate 2-associated phosphatidylinositol-3' kinase activation, and impaired atypical protein kinase C (zeta/lambda) activation in myotubes from obese patients with impaired glucose tolerance.

Journal: Diabetes20020401

Title: Cell density and N-cadherin interactions regulate cell proliferation in the sensory epithelia of the inner ear.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20020401

Title: PAF-stimulated protein tyrosine phosphorylation in hippocampus: involvement of NO synthase.

Journal: Neurochemical research20020401

Title: Cyclin G recruits PP2A to dephosphorylate Mdm2.

Journal: Molecular cell20020401

Title: Comparison of alterations in insulin signalling pathway in adipocytes from Type II diabetic pregnant women and women with gestational diabetes mellitus.

Journal: Diabetologia20020401

Title: Overexpression of ganglioside GM1 results in the dispersion of platelet-derived growth factor receptor from glycolipid-enriched microdomains and in the suppression of cell growth signals.

Journal: The Journal of biological chemistry20020329

Title: The catalytic mechanism of Cdc25A phosphatase.

Journal: The Journal of biological chemistry20020329

Title: Constitutive activation of Stat3alpha in brain tumors: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2).

Journal: Oncogene20020327

Title: Design and characterization of an improved protein tyrosine phosphatase substrate-trapping mutant.

Journal: Biochemistry20020326

Title: Identification of a new segment involved in cagA 3' region variation of Helicobacter pylori.

Journal: FEMS immunology and medical microbiology20020325

Title: Coexpression of oncostatin M and its receptors and evidence for STAT3 activation in human ovarian carcinomas.

Journal: Cytokine20020321

Title: Endosomal proteolysis of internalized insulin at the C-terminal region of the B chain by cathepsin D.

Journal: The Journal of biological chemistry20020315

Title: Fibroblast growth factor receptor 1 phosphotyrosine 766: molecular target for prevention of progression of prostate tumors to malignancy.

Journal: Cancer research20020315

Title: SHP-2 is involved in heterodimer specific loss of phosphorylation of Tyr771 in the PDGF beta-receptor.

Journal: Oncogene20020314

Title: Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin.

Journal: The Journal of biological chemistry20020308

Title: Specificity of interleukin-2 receptor gamma chain superfamily cytokines is mediated by insulin receptor substrate-dependent pathway.

Journal: The Journal of biological chemistry20020308

Title: Overexpression of protein-tyrosine phosphatase PTP sigma is linked to impaired glucose-induced insulin secretion in hereditary diabetic Goto-Kakizaki rats.

Journal: Biochemical and biophysical research communications20020308

Title: Activation of STAT5 triggers proliferation and contributes to anti-apoptotic signalling mediated by the oncogenic Xmrk kinase.

Journal: Oncogene20020307

Title: Membrane-anchored Cbl suppresses Hck protein-tyrosine kinase mediated cellular transformation.

Journal: Oncogene20020307

Title: Structural basis for the recognition of a bisphosphorylated MAP kinase peptide by human VHR protein Phosphatase.

Journal: Biochemistry20020305

Title: Insulin receptor substrate-3 functions as transcriptional activator in the nucleus.

Journal: The Journal of biological chemistry20020301

Title: Growth inhibition and apoptosis of myeloma cells by the CDK inhibitor flavopiridol.

Journal: Leukemia research20020301

Title: Changes in membrane microenvironment and signal transduction in platelets from NIDDM patients-a pilot study.

Journal: Clinica chimica acta; international journal of clinical chemistry20020301

Title: N-3 polyunsaturated fatty acids prevent the defect of insulin receptor signaling in muscle.

Journal: American journal of physiology. Endocrinology and metabolism20020301

Title: From structure to function: YrbI from Haemophilus influenzae (HI1679) is a phosphatase.

Journal: Proteins20020301

Title: Fermented wheat germ extract induces apoptosis and downregulation of major histocompatibility complex class I proteins in tumor T and B cell lines.

Journal: International journal of oncology20020301

Title: An immunohistochemical approach to monitor the prolactin-induced activation of the JAK2/STAT5 pathway in pancreatic islets of Langerhans.

Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society20020301

Title: Ecdysone-inducible expression of oncogenic Ha-Ras in NIH 3T3 cells leads to transient nuclear localization of activated extracellular signal-regulated kinase regulated by mitogen-activated protein kinase phosphatase-1.

Journal: The Biochemical journal20020301

Title: Phosphorylation of the N-terminal and C-terminal CD3-epsilon-ITAM tyrosines is differentially regulated in T cells.

Journal: Biochemical and biophysical research communications20020301

Title: Regulation of angiopoietin and Tie-2 receptor expression in non-reproductive tissues by estrogen.

Journal: Steroids20020301

Title: Receptor-facilitated antigen presentation requires the recruitment of B cell linker protein to Igalpha.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020301

Title: Lipid raft heterogeneity in human peripheral blood T lymphoblasts: a mechanism for regulating the initiation of TCR signal transduction.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020301

Title: Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes.

Journal: Diabetes20020301

Title: Interdependence of steroidogenesis and shape changes in Y1 adrenocortical cells: studies with inhibitors of phosphoprotein phosphatases.

Journal: The Journal of endocrinology20020301

Title: 14-3-3 facilitates insulin-stimulated intracellular trafficking of insulin receptor substrate 1.

Journal: Molecular endocrinology (Baltimore, Md.)20020301

Title: Retinoic acid increases proliferation rate of GL-15 glioma cells, involving activation of STAT-3 transcription factor.

Journal: Journal of neuroscience research20020301

Title: Fragmentation of phosphopeptides by atmospheric pressure MALDI and ESI/Ion trap mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry20020301

Title: A tyrosine-phosphorylated 12-amino-acid sequence of enteropathogenic Escherichia coli Tir binds the host adaptor protein Nck and is required for Nck localization to actin pedestals.

Journal: Molecular microbiology20020301

Title: Protein kinases activities in erythrocyte membranes of asphyxiated newborns.

Journal: Clinical biochemistry20020301

Title: Phosphotyrosine-binding domains in signal transduction.

Journal: Nature reviews. Molecular cell biology20020301

Title: Inhibition of lymphocyte kinase Lck and phosphatidylinositol 3-kinase by a novel immunosuppressant, lymphostin.

Journal: Bioscience, biotechnology, and biochemistry20020301

Title: Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2.

Journal: The Journal of biological chemistry20020222

Title: Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells.

Journal: Oncogene20020221

Title: PTEN regulates tumor cell adhesion of colon carcinoma cells under dynamic conditions of fluid flow.

Journal: Oncogene20020221

Title: Can we infer peptide recognition specificity mediated by SH3 domains?

Journal: FEBS letters20020220

Title: PTB or not PTB -- that is the question.

Journal: FEBS letters20020220

Title: WaaP of Pseudomonas aeruginosa is a novel eukaryotic type protein-tyrosine kinase as well as a sugar kinase essential for the biosynthesis of core lipopolysaccharide.

Journal: The Journal of biological chemistry20020215

Title: Lyn tyrosine kinase is important for IL-5-stimulated eosinophil differentiation.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020215

Title: Regulation of postaggregation events induced by protease-activated receptor 1 ligation in human platelets: evidence of differential signaling pathways.

Journal: Archives of biochemistry and biophysics20020215

Title: Dissection of the energetic coupling across the Src SH2 domain-tyrosyl phosphopeptide interface.

Journal: Journal of molecular biology20020215

Title: Dephosphorylation failure of tyrosine-phosphorylated STAT1 in IFN-stimulated Sendai virus C protein-expressing cells.

Journal: Virology20020215

Title: The kinase-null EphB6 receptor undergoes transphosphorylation in a complex with EphB1.

Journal: The Journal of biological chemistry20020208

Title: Human endothelial Pyk2 is expressed in two isoforms and associates with paxillin and p130Cas.

Journal: Biochemical and biophysical research communications20020208

Title: C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus.

Journal: Oncogene20020207

Title: Calcium-dependent activation of Pyk2 by hypoxia.

Journal: Cellular signalling20020201

Title: Regulation of phospholipase C-gamma 2 via phosphatidylinositol 3-kinase in macrophages.

Journal: Cellular signalling20020201

Title: Erythropoietin receptor-dependent erythroid colony-forming unit development: capacities of Y343 and phosphotyrosine-null receptor forms.

Journal: Blood20020201

Title: Autoinhibitory mechanisms in receptor tyrosine kinases.

Journal: Frontiers in bioscience : a journal and virtual library20020201

Title: Requirement of Ca(2+) and PKCdelta for Janus kinase 2 activation by angiotensin II: involvement of PYK2.

Journal: Molecular endocrinology (Baltimore, Md.)20020201

Title: Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele.

Journal: Cancer research20020201

Title: Tumor necrosis factor alpha stimulates invasion of Src-activated intestinal cells.

Journal: Gastroenterology20020201

Title: Identification of an IGF-1R kinase regulatory phosphatase using the fission yeast Schizosaccharomyces pombe and a GFP tagged IGF-1R in mammalian cells.

Journal: Molecular pathology : MP20020201

Title: Detection of dual TEL-ABL transcripts and a Tel-Abl protein containing phosphotyrosine in a chronic myeloid leukemia patient.

Journal: Leukemia20020201

Title: Phosphorylation and dephosphorylation of histidine residues in proteins.

Journal: European journal of biochemistry20020201

Title: Phosphopeptide detection and sequencing by matrix-assisted laser desorption/ionization quadrupole time-of-flight tandem mass spectrometry.

Journal: Journal of mass spectrometry : JMS20020201

Title: Low density detergent-insoluble membrane of Xenopus eggs: subcellular microdomain for tyrosine kinase signaling in fertilization.

Journal: Development (Cambridge, England)20020201

Title: Induction of chondrocyte growth arrest by FGF: transcriptional and cytoskeletal alterations.

Journal: Journal of cell science20020201

Title: Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family.

Journal: Immunogenetics20020201

Title: Targeting the EGF receptor in ovarian cancer with the tyrosine kinase inhibitor ZD 1839 ('Iressa').

Journal: British journal of cancer20020201

Title: Endothelin-1--induced enhancement of coronary smooth muscle contraction via MAPK-dependent and MAPK-independent [Ca(2+)](i) sensitization pathways.

Journal: Hypertension (Dallas, Tex. : 1979)20020201

Title: Overview of rationale and clinical trials with signal transduction inhibitors in lung cancer.

Journal: Seminars in oncology20020201

Title: Analysis of genetic and epigenetic alterations of the PTEN gene in gastric cancer.

Journal: Virchows Archiv : an international journal of pathology20020201

Title: Assay and screening methods for bioactive substances based on cellular signaling pathways.

Journal: Journal of biotechnology20020201

Title: Role of KCNQ1 in the cell swelling-induced enhancement of the slowly activating delayed rectifier K(+) current.

Journal: The Japanese journal of physiology20020201

Title: Enriched levels of erythropoietin in human umbilical cord blood stimulate hematopoietic progenitor cells.

Journal: Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB)20020201

Title: Production of antibodies that recognize specific tyrosine-phosphorylated peptides.

Journal: Current protocols in cell biology20020201

Title: Regulation of p73 by c-Abl through the p38 MAP kinase pathway.

Journal: Oncogene20020131

Title: Sendai virus C protein impairs both phosphorylation and dephosphorylation processes of Stat1.

Journal: FEBS letters20020130

Title: Reduced expression of EphrinA1 (EFNA1) inhibits three-dimensional growth of HT29 colon carcinoma cells.

Journal: Cancer letters20020125

Title: SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein.

Journal: Science (New York, N.Y.)20020125

Title: The upper cytokine-binding module and the Ig-like domain of the leukaemia inhibitory factor (LIF) receptor are sufficient for a functional LIF receptor complex.

Journal: Journal of molecular biology20020125

Title: Involvement of phosphorylation of Tyr-31 and Tyr-118 of paxillin in MM1 cancer cell migration.

Journal: International journal of cancer20020120

Title: Significance of phosphotyrosine proteins, Bcl-2 and p53 for apoptosis in resting B-chronic lymphocytic leukemia (CLL) cells.

Journal: International journal of cancer20020120

Title: Replacement of N-terminal portions of TGF-alpha with corresponding heregulin sequences affects ligand-induced receptor signaling and intoxication of tumor cells by chimeric growth-factor toxins.

Journal: International journal of cancer20020120

Title: Coordinated activation of autophosphorylation sites in the RET receptor tyrosine kinase: importance of tyrosine 1062 for GDNF mediated neuronal differentiation and survival.

Journal: The Journal of biological chemistry20020118

Title: Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors.

Journal: Science (New York, N.Y.)20020118

Title: Calorimetric and structural studies of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide inhibitors of Src SH2 domain binding.

Journal: Journal of the American Chemical Society20020116

Title: Meeting at mitosis: cell cycle-specific regulation of c-Src by RPTPalpha.

Journal: Science's STKE : signal transduction knowledge environment20020115

Title: Inhibition of the Bcr-Abl oncoprotein by Bcr requires phosphoserine 354.

Journal: Cancer research20020115

Title: Tyrosine phosphorylation mapping of the epidermal growth factor receptor signaling pathway.

Journal: The Journal of biological chemistry20020111

Title: Light-dependent association of Src with photoreceptor rod outer segment membrane proteins in vivo.

Journal: The Journal of biological chemistry20020111

Title: Temperature dependence of the epidermal growth factor receptor signaling network can be accounted for by a kinetic model.

Journal: Biochemistry20020108

Title: 19F NMR studies of vaccinia type IB topoisomerase. Conformational dynamics of the bound DNA substrate.

Journal: The Journal of biological chemistry20020104

Title: Discrimination between phosphotyrosine-mediated signaling properties of conventional and neuronal Shc adapter molecules.

Journal: Oncogene20020103

Title: Paxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase.

Journal: Oncogene20020103

Title: Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d.

Journal: Nature immunology20020101

Title: Isolation and characterization of a protein-tyrosine kinase and a phosphotyrosine-protein phosphatase from Klebsiella pneumoniae.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology20020101

Title: Effect of autophosphorylation on the catalytic and regulatory properties of protein tyrosine kinase Src.

Journal: Archives of biochemistry and biophysics20020101

Title: Dockers at the crossroads.

Journal: Cellular signalling20020101

Title: Biology of the gonadotropin-releasing hormone system in gynecological cancers.

Journal: European journal of endocrinology20020101

Title: Fyn tyrosine kinase in Sertoli cells is involved in mouse spermatogenesis.

Journal: Biology of reproduction20020101

Title: CD5-negative regulation of B cell receptor signaling pathways originates from tyrosine residue Y429 outside an immunoreceptor tyrosine-based inhibitory motif.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020101

Title: Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020101

Title: Platelet endothelial cell adhesion molecule-1 signaling inhibits the activation of human platelets.

Journal: Blood20020101

Title: Human T-cell leukemia virus type 2 induces survival and proliferation of CD34(+) TF-1 cells through activation of STAT1 and STAT5 by secretion of interferon-gamma and granulocyte macrophage-colony-stimulating factor.

Journal: Blood20020101

Title: Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-beta peptide exposure: involvement of Src family protein kinases.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20020101

Title: A XerD recombinase with unusual active site motifs in Streptococcus pneumoniae.

Journal: Journal of molecular microbiology and biotechnology20020101

Title: Linkage of rapid estrogen action to MAPK activation by ERalpha-Shc association and Shc pathway activation.

Journal: Molecular endocrinology (Baltimore, Md.)20020101

Title: Impaired insulin signaling in the liver of transgenic rats with low circulating growth hormone levels.

Journal: The Journal of endocrinology20020101

Title: Role for adapter proteins in costimulatory signals of CD2 and IL-2 on NK cell activation.

Journal: Molecular immunology20020101

Title: Evidence for the epidermal growth factor receptor as a target for lung cancer prevention.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20020101

Title: MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.

Journal: BMC cell biology20020101

Title: Characterization of a phosphorylated peptide and peptoid and peptoid-peptide hybrids by mass spectrometry.

Journal: Journal of mass spectrometry : JMS20020101

Title: Electrophoretic analysis of phosphorylation of the yeast 20S proteasome.

Journal: Electrophoresis20020101

Title: Kinetics and active site dynamics of Staphylococcus aureus arsenate reductase.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry20020101

Title: Delta opioid activation of the mitogen-activated protein kinase cascade does not require transphosphorylation of receptor tyrosine kinases.

Journal: BMC pharmacology20020101

Title: Activation of human somatostatin receptor 2 promotes apoptosis through a mechanism that is independent from induction of p53.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20020101

Title: Bis(maltolato)oxovanadium(IV) inhibits the activity of PTP1B in Zucker rat skeletal muscle in vivo.

Journal: Molecular and cellular biochemistry20020101

Title: Endogenous regucalcin suppresses the enhancement of protein phosphatase activity in the cytosol and nucleus of kidney cortex in calcium-administered rats.

Journal: Journal of cellular biochemistry20020101

Title: Hisactophilin is involved in osmoprotection in Dictyostelium.

Journal: BMC biochemistry20020101

Title: Glucocorticoids: do we know how they work?

Journal: Arthritis research20020101

Title: Wheat functional genomics and engineering crop improvement.

Journal: Genome biology20020101

Title: The role of the Zn(II) binding domain in the mechanism of E. coli DNA topoisomerase I.

Journal: BMC biochemistry20020101

Title: Evaluation of L-selectin expression and assessment of protein tyrosine phosphorylation in bovine polymorphonuclear neutrophil leukocytes around parturition.

Journal: Veterinary research20020101

Title: Characterisation and expression of a PP1 serine/threonine protein phosphatase (PfPP1) from the malaria parasite, Plasmodium falciparum: demonstration of its essential role using RNA interference.

Journal: Malaria journal20020101

Title: Retroviral expression of a kinase-defective IGF-I receptor suppresses growth and causes apoptosis of CHO and U87 cells in-vivo.

Journal: BMC cancer20020101

Title: Effect of anti-IL-2Ralpha antibody on IL-2-induced Jak/STAT signaling.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons20020101

Title: The paradigm of IL-6: from basic science to medicine.

Journal: Arthritis research20020101

Title: Purification and characterization of protein tyrosine phosphatase PTP-MEG2.

Journal: Journal of cellular biochemistry20020101

Title: Sam68 associates with the SH3 domains of Grb2 recruiting GAP to the Grb2-SOS complex in insulin receptor signaling.

Journal: Journal of cellular biochemistry20020101

Title: A p130Cas tyrosine phosphorylated substrate domain decoy disrupts v-crk signaling.

Journal: BMC cell biology20020101

Title: Ecto-phosphatase activity on the cell surface of Crithidia deanei.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences20020101

Title: MAP kinase phosphatases.

Journal: Genome biology20020101

Title: Protein phosphatase-2A modulates the serine and tyrosine phosphorylation of paxillin in Lewis lung carcinoma tumor variants.

Journal: Clinical & experimental metastasis20020101

Title: alpha2-Heremans Schmid glycoprotein, a putative inhibitor of tyrosine kinase, prevents glucose toxicity associated with cardiomyocyte dysfunction.

Journal: Diabetes/metabolism research and reviews20020101

Title: Alpha2-HS glycoprotein: a protein in search of a function.

Journal: Diabetes/metabolism research and reviews20020101

Title: Distinct signal transduction processes by IL-4 and IL-13 and influences from the Q551R variant of the human IL-4 receptor alpha chain.

Journal: Respiratory research20020101

Title: Expression of a releasable form of annexin II by human keratinocytes.

Journal: Journal of cellular biochemistry20020101

Title: Expression of the Fe65 adapter protein in adult and developing mouse brain.

Journal: Neuroscience20020101

Title: Molecular recognition by SH2 domains.

Journal: Advances in protein chemistry20020101

Title: Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes.

Journal: BMC immunology20020101

Title: Tyrosine phosphorylation of eukaryotic proteins and translocated intimin receptor by enteropathogenic Escherichia coli.

Journal: Methods in enzymology20020101

Title: Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells.

Journal: BMC biochemistry20020101

Title: Inhibition of shear-stress-induced platelet aggregation and phosphotyrosine signaling by GPIIb-IIIa antagonists.

Journal: Annals of biomedical engineering20020101

Title: Cytotoxic activity of a new lipid formulation of doxorubicin in cell lines and primary tumor cells.

Journal: Anticancer research20020101

Title: Tyrosine phosphorylation in human lymphomas.

Journal: The Histochemical journal20020101

Title: Abstracts of the Fourth International Symposium on Molecular Insect Science. May 28-June 2, 2002. Tucson, Arizona, USA.

Journal: Journal of insect science (Online)20020101

Title: Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics.

Journal: Journal of medicinal chemistry20011220

Title: Design and synthesis of non-peptidic inhibitors for the Syk C-terminal SH2 domain based on structure-based in-silico screening.

Journal: Journal of medicinal chemistry20011220

Title: Role of tyrosine kinase activity in alpha-adrenergic inhibition of the beta-adrenergically regulated L-type Ca(2+) current in guinea-pig ventricular myocytes.

Journal: The Journal of physiology20011215

Title: Intracellular distribution of lysosomal sialidase is controlled by the internalization signal in its cytoplasmic tail.

Journal: The Journal of biological chemistry20011207

Title: The human protein HSPC021 interacts with Int-6 and is associated with eukaryotic translation initiation factor 3.

Journal: The Journal of biological chemistry20011207

Title: Phosphorylation and structure-based functional studies reveal a positive and a negative role for the activation loop of the c-Abl tyrosine kinase.

Journal: Oncogene20011206

Title: H(2)O(2)-mediated permeability II: importance of tyrosine phosphatase and kinase activity.

Journal: American journal of physiology. Cell physiology20011201

Title: Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome.

Journal: Nature genetics20011201

Title: Regulation of Id2 gene expression by the type 1 IGF receptor and the insulin receptor substrate-1.

Journal: Endocrinology20011201

Title: Tyrosine phosphorylation-dependent and -independent role of Shc in the regulation of IGF-1-induced mitogenesis and glycogen synthesis.

Journal: Endocrinology20011201

Title: C-terminal peptide of thrombospondin-1 induces platelet aggregation through the Fc receptor gamma-chain-associated signaling pathway and by agglutination.

Journal: Blood20011201

Title: The TEL/PDGFbetaR fusion in chronic myelomonocytic leukemia signals through STAT5-dependent and STAT5-independent pathways.

Journal: Blood20011201

Title: Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart.

Journal: Diabetes20011201

Title: Insulin signal transduction in skeletal muscle from glucose-intolerant relatives of type 2 diabetic patients [corrected].

Journal: Diabetes20011201

Title: Activation of JAK2 by the oxidative stress generated with oxidized low-density lipoprotein.

Journal: Free radical biology & medicine20011201

Title: Nitric oxide increases albumin permeability of isolated rat glomeruli via a phosphorylation-dependent mechanism.

Journal: Journal of the American Society of Nephrology : JASN20011201

Title: Systemic biochemical effects of inhaled NO in rats: increased expressions of NOS III, nitrotyrosine-, and phosphotyrosine-immunoreactive proteins in liver and kidney tissues.

Journal: Nitric oxide : biology and chemistry20011201

Title: Role of tyrosine kinases and the tyrosine phosphatase SptP in the interaction of Salmonella with host cells.

Journal: Cellular microbiology20011201

Title: The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation.

Journal: Structure (London, England : 1993)20011201

Title: Hierarchy of simulation models in predicting molecular recognition mechanisms from the binding energy landscapes: structural analysis of the peptide complexes with SH2 domains.

Journal: Proteins20011201

Title: CD28 as a molecular amplifier extending TCR ligation and signaling capabilities.

Journal: Immunity20011201

Title: Tyrosine kinase activation in breast carcinoma with correlation to HER-2/neu gene amplification and receptor overexpression.

Journal: Human pathology20011201

Title: Design and application of a cytokine-receptor-based interaction trap.

Journal: Nature cell biology20011201

Title: [The activation of the phosphotyrosine phosphatase eta is responsible for the somatostatin inhibition of PCCl3 thyroid cell proliferation].

Journal: Minerva endocrinologica20011201

Title: Alpha-tocopherol modulates tyrosine phosphorylation in human neutrophils by inhibition of protein kinase C activity and activation of tyrosine phosphatases.

Journal: Free radical research20011201

Title: Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways.

Journal: Molecular medicine (Cambridge, Mass.)20011201

Title: Basal keratinocytes from uninvolved psoriatic skin exhibit accelerated spreading and focal adhesion kinase responsiveness to fibronectin.

Journal: The Journal of investigative dermatology20011201

Title: Effects of age on elements of insulin-signaling pathway in central nervous system of rats.

Journal: Endocrine20011201

Title: Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation.

Journal: The Journal of biological chemistry20011130

Title: Voltage-independent inhibition of P/Q-type Ca2+ channels in adrenal chromaffin cells via a neuronal Ca2+ sensor-1-dependent pathway involves Src family tyrosine kinase.

Journal: The Journal of biological chemistry20011130

Title: A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth.

Journal: Cell20011130

Title: S-Adenosyl-L-homocysteine hydrolase is sequestered into actin rods in Dictyostelium discoideum spores.

Journal: FEBS letters20011123

Title: Src family kinases mediate receptor-stimulated, phosphoinositide 3-kinase-dependent, tyrosine phosphorylation of dual adaptor for phosphotyrosine and 3-phosphoinositides-1 in endothelial and B cell lines.

Journal: The Journal of biological chemistry20011116

Title: HSH2: a novel SH2 domain-containing adapter protein involved in tyrosine kinase signaling in hematopoietic cells.

Journal: Biochemical and biophysical research communications20011116

Title: Multiple stimuli induce tyrosine phosphorylation of the Crk-binding sites of paxillin.

Journal: The Biochemical journal20011115

Title: C-terminal heparin-binding domain of fibronectin regulates integrin-mediated cell spreading but not the activation of mitogen-activated protein kinase.

Journal: The Biochemical journal20011115

Title: Association of FcgammaRII with low-density detergent-resistant membranes is important for cross-linking-dependent initiation of the tyrosine phosphorylation pathway and superoxide generation.

Journal: Journal of immunology (Baltimore, Md. : 1950)20011115

Title: Activation of Syk protein tyrosine kinase through interaction with integrin beta cytoplasmic domains.

Journal: Current biology : CB20011113

Title: Tyrosine phosphorylation of the catalytic subunit p110 of phosphatidylinositol-3 kinase induced by HMG-CoA reductase inhibitor inhibits its kinase activity in L6 myoblasts.

Journal: FEBS letters20011109

Title: Insulin receptor substrate-1 pleckstrin homology and phosphotyrosine-binding domains are both involved in plasma membrane targeting.

Journal: The Journal of biological chemistry20011102

Title: The roles of phosphatidylinositol 3-kinase and protein kinase Czeta for thrombopoietin-induced mitogen-activated protein kinase activation in primary murine megakaryocytes.

Journal: The Journal of biological chemistry20011102

Title: Modulation of nicotinic acetylcholine receptor turnover by tyrosine phosphorylation in rat myotubes.

Journal: Neuroscience letters20011102

Title: Signal transduction by VEGF receptor-1 wild type and mutant proteins.

Journal: Cellular signalling20011101

Title: Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A.

Journal: The Biochemical journal20011101

Title: SH2 and SH3 domains as targets for anti-proliferative agents.

Journal: Critical reviews in oncology/hematology20011101

Title: Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells.

Journal: The EMBO journal20011101

Title: Two mechanisms activate PTPalpha during mitosis.

Journal: The EMBO journal20011101

Title: The genetics of signal transduction and the outcome of diagnostic tests in growth retardation.

Journal: The Journal of endocrinology20011101

Title: Chemokine receptor dimerization: two are better than one.

Journal: Trends in immunology20011101

Title: Enhanced expression of Fc alpha receptor I on blood phagocytes of patients with gram-negative bacteremia is associated with tyrosine phosphorylation of the FcR-gamma subunit.

Journal: Shock (Augusta, Ga.)20011101

Title: Protein tyrosine phosphatase genes downregulated in melanoma.

Journal: The Journal of investigative dermatology20011101

Title: Protein kinase C-independent stimulation of activator protein-1 and c-Jun N-terminal kinase activity in human endometrial cancer cells by the LHRH agonist triptorelin.

Journal: European journal of endocrinology20011101

Title: Phosphorylation of tyrosine 972 of the Helicobacter pylori CagA protein is essential for induction of a scattering phenotype in gastric epithelial cells.

Journal: Molecular microbiology20011101

Title: Alterations of phospholipase C isozymes in rat cerebral cortex through hyperoxia.

Journal: Biological & pharmaceutical bulletin20011101

Title: Structure of the type III secretion and substrate-binding domain of Yersinia YopH phosphatase.

Journal: Molecular microbiology20011101

Title: Role of host phosphotyrosine phosphatase SHP-1 in the development of murine leishmaniasis.

Journal: European journal of immunology20011101

Title: Topographic changes of focal adhesion components and modulation of p125FAK activation in stretched human periodontal ligament fibroblasts.

Journal: Journal of dental research20011101

Title: Early cell adhesion events differ between osteoporotic and non-osteoporotic osteoblasts.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society20011101

Title: [A variety of functions of conventional and neuronal Shc adapter molecules in phosphotyrosine-mediated signalings].

Journal: Seikagaku. The Journal of Japanese Biochemical Society20011101

Title: Loss of phosphotyrosine phosphatase activity and changes in the tyrosine phosphorylation state of proteins after storage of sheep platelets in plasma or Seto solution at 4 degrees C.

Journal: Vox sanguinis20011101

Title: Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid.

Journal: The Journal of biological chemistry20011026

Title: Regulation of IRS-2 tyrosine phosphorylation in fasting and diabetes.

Journal: Molecular and cellular endocrinology20011025

Title: Adhesion via CD43 induces Syk activation and cell proliferation in TF-1 cells.

Journal: Biochemical and biophysical research communications20011019

Title: Phosphorylation of human N-myristoyltransferase by N-myristoylated SRC family tyrosine kinase members.

Journal: Biochemical and biophysical research communications20011019

Title: Involvement of tyrosine phosphatase PTP1D in the inhibition of interleukin-6-induced Stat3 signaling by alpha-thrombin.

Journal: Biochemical and biophysical research communications20011019

Title: Integrated src kinase and costimulatory activity enhances signal transduction through single-chain chimeric receptors in T lymphocytes.

Journal: Blood20011015

Title: The intrinsic ability of AFAP-110 to alter actin filament integrity is linked with its ability to also activate cellular tyrosine kinases.

Journal: Oncogene20011004

Title: Src directly tyrosine-phosphorylates STAT5 on its activation site and is involved in erythropoietin-induced signaling pathway.

Journal: Oncogene20011004

Title: Integrin tyrosine phosphorylation in platelet signaling.

Journal: Current opinion in cell biology20011001

Title: PRL, placental lactogen, and GH induce NA(+)/taurocholate-cotransporting polypeptide gene expression by activating signal transducer and activator of transcription-5 in liver cells.

Journal: Endocrinology20011001

Title: Hypochlorous acid stimulation of the mitogen-activated protein kinase pathway enhances cell survival.

Journal: Archives of biochemistry and biophysics20011001

Title: The activation of the phosphotyrosine phosphatase eta (r-PTP eta) is responsible for the somatostatin inhibition of PC Cl3 thyroid cell proliferation.

Journal: Molecular endocrinology (Baltimore, Md.)20011001

Title: Glial cell-derived neurotrophic factor (GDNF)-induced migration and signal transduction in corneal epithelial cells.

Journal: Investigative ophthalmology & visual science20011001

Title: Lovastatin-induced cytoskeletal reorganization in lens epithelial cells: role of Rho GTPases.

Journal: Investigative ophthalmology & visual science20011001

Title: Histological and functional analysis of vascular smooth muscle cells in a novel culture system with honeycomb-like structure.

Journal: Atherosclerosis20011001

Title: Regulation of epidermal growth factor receptor expression in human melanocytes.

Journal: Experimental dermatology20011001

Title: Crystal-induced neutrophil activation. VII. Involvement of Syk in the responses to monosodium urate crystals.

Journal: Journal of leukocyte biology20011001

Title: Integrin-mediated differentiation of a pancreatic carcinoma cell line is independent of FAK or MAPK activation levels.

Journal: Pancreas20011001

Title: Promegapoietin, a family of chimeric growth factors, supports megakaryocyte development through activation of IL-3 and c-Mpl ligand signaling pathways.

Journal: Experimental hematology20011001

Title: 14-3-3 proteins; bringing new definitions to scaffolding.

Journal: Oncogene20011001

Title: Expression of pyrimidine 5'-nucleotidase subclass I during erythrocyte maturation in rats.

Journal: Journal of hematotherapy & stem cell research20011001

Title: Site-specific incorporation of a phosphotyrosine mimetic reveals a role for tyrosine phosphorylation of SHP-2 in cell signaling.

Journal: Molecular cell20011001

Title: Molecular basis for the insulinomimetic effects of C-peptide.

Journal: Diabetologia20011001

Title: SH2-containing inositol phosphatase 2 negatively regulates insulin-induced glycogen synthesis in L6 myotubes.

Journal: Diabetologia20011001

Title: Differential regulation of T cell receptor-mediated Th1 cell IFN-gamma production and proliferation by divergent cAMP-mediated redox pathways.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research20011001

Title: Evidence that increased tyrosine phosphorylation causes disassembly of adherens junctions but does not perturb paracellular permeability in Caco-2 cells.

Journal: Tissue & cell20011001

Title: EphB/syndecan-2 signaling in dendritic spine morphogenesis.

Journal: Neuron20010927

Title: G2 phase cell cycle arrest in human skin following UV irradiation.

Journal: Oncogene20010927

Title: Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation.

Journal: Oncogene20010927

Title: Enhanced sensitivity of insulin-resistant adipocytes to vanadate is associated with oxidative stress and decreased reduction of vanadate (+5) to vanadyl (+4).

Journal: The Journal of biological chemistry20010921

Title: Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region.

Journal: Cell20010921

Title: Tissue-specific regulation of early steps in insulin action in septic rats.

Journal: Life sciences20010921

Title: Beta-arrestin- and c-Src-dependent degradation of G-protein-coupled receptor kinase 2.

Journal: The EMBO journal20010917

Title: Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: possible role of Sam68.

Journal: Cellular immunology20010915

Title: Palmitoylation of caveolin-1 at a single site (Cys-156) controls its coupling to the c-Src tyrosine kinase: targeting of dually acylated molecules (GPI-linked, transmembrane, or cytoplasmic) to caveolae effectively uncouples c-Src and caveolin-1 (TYR-14).

Journal: The Journal of biological chemistry20010914

Title: The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals.

Journal: Nature20010913

Title: Phosphorylation-induced activation of tilapia nonspecific cytotoxic cells by serum cytokines.

Journal: Diseases of aquatic organisms20010912

Title: 14-3-3 protein-activated and autoinhibited forms of plasma membrane H(+)-ATPase.

Journal: Biochemical and biophysical research communications20010907

Title: Mammary glands reconstituted with Neu/ErbB2 transformed HC11 cells provide a novel orthotopic tumor model for testing anti-cancer agents.

Journal: Oncogene20010906

Title: A novel phosphotyrosine mimetic 4'-carboxymethyloxy-3'-phosphonophenylalanine (Cpp): exploitation in the design of nonpeptide inhibitors of pp60(Src) SH2 domain.

Journal: Bioorganic & medicinal chemistry letters20010903

Title: The interaction of dystrophin with beta-dystroglycan is regulated by tyrosine phosphorylation.

Journal: Cellular signalling20010901

Title: Activation of the transcription factor NF-kappaB by the erythropoietin receptor: structural requirements and biological significance.

Journal: Cellular signalling20010901

Title: Cell cycling determines integrin-mediated adhesion in osteoblastic ROS 17/2.8 cells exposed to space-related conditions.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20010901

Title: Crystal structure of the phosphatidylinositol 3,4-bisphosphate-binding pleckstrin homology (PH) domain of tandem PH-domain-containing protein 1 (TAPP1): molecular basis of lipid specificity.

Journal: The Biochemical journal20010901

Title: Colony-stimulating factor-1 (CSF-1) receptor-mediated macrophage differentiation in myeloid cells: a role for tyrosine 559-dependent protein phosphatase 2A (PP2A) activity.

Journal: The Biochemical journal20010901

Title: Direct identification of a major autophosphorylation site on vascular endothelial growth factor receptor Flt-1 that mediates phosphatidylinositol 3'-kinase binding.

Journal: The Biochemical journal20010901

Title: Tyrosine phosphorylation following alterations in arteriolar intraluminal pressure and wall tension.

Journal: American journal of physiology. Heart and circulatory physiology20010901

Title: Capacitation is associated with tyrosine phosphorylation and tyrosine kinase-like activity of pig sperm proteins.

Journal: Biology of reproduction20010901

Title: Cyclic AMP and acidic fibroblast growth factor have opposing effects on tight and adherens junctions in microvascular endothelial cells in vitro.

Journal: Microvascular research20010901

Title: c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20010901

Title: Relaxin signalling links tyrosine phosphorylation to phosphodiesterase and adenylyl cyclase activity.

Journal: Molecular human reproduction20010901

Title: Inhibition of tyrosine kinase activity induces caspase-dependent apoptosis in anaplastic large cell lymphoma with NPM-ALK (p80) fusion protein.

Journal: Experimental hematology20010901

Title: Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells.

Journal: Nature cell biology20010901

Title: Capacitation dependent activation of tyrosine phosphorylation generates two sperm head plasma membrane proteins with high primary binding affinity for the zona pellucida.

Journal: Molecular reproduction and development20010901

Title: Identifying substrates for endothelium-specific Tie-2 receptor tyrosine kinase from phage-displayed peptide libraries for high throughput screening.

Journal: Combinatorial chemistry & high throughput screening20010901

Title: Angiotensin II type 2 receptor inhibits epidermal growth factor receptor transactivation by increasing association of SHP-1 tyrosine phosphatase.

Journal: Hypertension (Dallas, Tex. : 1979)20010901

Title: Parallel assessment of tyrosine phosphorylation and nuclear targeting of proteins.

Journal: BioTechniques20010901

Title: Kinetic characterization of the changes in protein tyrosine phosphorylation of membranes, cytosolic Ca2+ concentration and viability in boar sperm populations selected by binding to oviductal epithelial cells.

Journal: Reproduction (Cambridge, England)20010901

Title: Modulation of Rho GTPases and the actin cytoskeleton by Yersinia outer proteins (Yops).

Journal: International journal of medical microbiology : IJMM20010901

Title: Adenovirus-mediated overexpression and stimulation of the human angiotensin II type 2 receptor in porcine cardiac fibroblasts does not modulate proliferation, collagen I mRNA expression and ERK1/ERK2 activity, but inhibits protein tyrosine phosphatases.

Journal: Journal of molecular medicine (Berlin, Germany)20010901

Title: 1H, 15N and 13C assignments of the N-terminal domain of Yersinia outer protein H in its apo form and in complex with a phosphotyrosine peptide.

Journal: Journal of biomolecular NMR20010901

Title: Identification of a tyrosine kinase-phosphorylated protein in arachidonic acid- and prostaglandin A(2)-treated cells in vitro.

Journal: Prostaglandins, leukotrienes, and essential fatty acids20010901

Title: Growth hormone receptor ubiquitination, endocytosis, and degradation are independent of signal transduction via Janus kinase 2.

Journal: The Journal of biological chemistry20010831

Title: ERK regulates the hepatocyte growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase.

Journal: The Journal of biological chemistry20010831

Title: Unique regulation of c-Jun N-terminal kinase by PYK2/CAK-beta in angiotensin II-stimulated vascular smooth muscle cells.

Journal: Biochemical and biophysical research communications20010831

Title: Preserved phosphorylation of RET receptor protein in spinal motor neurons of patients with amyotrophic lateral sclerosis: an immunohistochemical study by a phosphorylation-specific antibody at tyrosine 1062.

Journal: Brain research20010831

Title: Electrostatic environment surrounding the activation loop phosphotyrosine in the oncoprotein v-Fps.

Journal: Biochemistry20010828

Title: A repertoire library that allows the selection of synthetic SH2s with altered binding specificities.

Journal: Oncogene20010823

Title: LAD-1, the Caenorhabditis elegans L1CAM homologue, participates in embryonic and gonadal morphogenesis and is a substrate for fibroblast growth factor receptor pathway-dependent phosphotyrosine-based signaling.

Journal: The Journal of cell biology20010820

Title: Nitrotyrosine mimics phosphotyrosine binding to the SH2 domain of the src family tyrosine kinase lyn.

Journal: FEBS letters20010817

Title: Requirement for tyrosine kinase-ERK1/2 signaling in alpha 1 beta 1 integrin-mediated collagen matrix remodeling by rat mesangial cells.

Journal: Experimental cell research20010815

Title: Growth-inhibitory effect of a streptococcal antitumor glycoprotein on human epidermoid carcinoma A431 cells: involvement of dephosphorylation of epidermal growth factor receptor.

Journal: Cancer research20010815

Title: Ron-mediated cytoplasmic signaling is dispensable for viability but is required to limit inflammatory responses.

Journal: The Journal of clinical investigation20010815

Title: Cooperative kinetics of human prostatic acid phosphatase.

Journal: Biochimica et biophysica acta20010813

Title: Multiple phosphorylation of membrane-associated calcium-dependent protein serine/threonine kinase in Streptomyces fradiae.

Journal: FEMS microbiology letters20010807

Title: Etk/Bmx tyrosine kinase activates Pak1 and regulates tumorigenicity of breast cancer cells.

Journal: The Journal of biological chemistry20010803

Title: Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts.

Journal: The Journal of biological chemistry20010803

Title: Insulin stimulates tyrosine phosphorylation and inactivation of protein-tyrosine phosphatase 1B in vivo.

Journal: The Journal of biological chemistry20010803

Title: Angiotensin II AT(2) receptors inhibit growth responses in proximal tubule cells.

Journal: American journal of physiology. Renal physiology20010801

Title: Platelet-derived growth factor stimulates phospholipase C-gamma 1, extracellular signal-regulated kinase, and arachidonic acid release in rat myometrial cells: contribution to cyclic 3',5'-adenosine monophosphate production and effect on cell proliferation.

Journal: Biology of reproduction20010801

Title: SH2 domain inhibition: a problem solved?

Journal: Current opinion in chemical biology20010801

Title: Growth hormone induces cellular insulin resistance by uncoupling phosphatidylinositol 3-kinase and its downstream signals in 3T3-L1 adipocytes.

Journal: Diabetes20010801

Title: Interferon-alpha drives T cell-mediated immunopathology in the intestine.

Journal: European journal of immunology20010801

Title: Cell adhesion-mediated drug resistance (CAM-DR) protects the K562 chronic myelogenous leukemia cell line from apoptosis induced by BCR/ABL inhibition, cytotoxic drugs, and gamma-irradiation.

Journal: Leukemia20010801

Title: Erythropoietin and erythropoietin receptors in the peripheral nervous system: changes after nerve injury.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20010801

Title: Growth hormone restores glucocorticoid-induced T cell suppression.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20010801

Title: Normalization of retinal vascular permeability in experimental diabetes with genistein.

Journal: Investigative ophthalmology & visual science20010801

Title: Tyrosine phosphorylation of the N-methyl-D-aspartate receptor by exogenous and postsynaptic density-associated Src-family kinases.

Journal: Journal of neurochemistry20010801

Title: Insulin-independent and wortmannin-resistant targeting of IRS-3 to the plasma membrane via its pleckstrin homology domain mediates a different interaction with the insulin receptor from that of IRS-1.

Journal: Diabetologia20010801

Title: Abnormal GH receptor signaling in children with idiopathic short stature.

Journal: The Journal of clinical endocrinology and metabolism20010801

Title: Rottlerin-independent attenuation of pervanadate-induced tyrosine phosphorylation events by protein kinase C-delta in hemopoietic cells.

Journal: Laboratory investigation; a journal of technical methods and pathology20010801

Title: De novo formation of focal complex-like structures in host cells by invading Streptococci.

Journal: Molecular microbiology20010801

Title: Induction of tyrosine phosphorylated proteins in THP-1 cells by Salmonella typhimurium, Pasteurella haemolytica and Haemophilus influenzae porins.

Journal: FEMS immunology and medical microbiology20010801

Title: Effect of increased intracellular melanin concentration on survival of human melanoma cells exposed to different wavelengths of UV radiation.

Journal: International journal of radiation biology20010801

Title: Utilization of a receptor reserve for effective amplification of mitogenic signaling by an epidermal growth factor mutant deficient in receptor activation.

Journal: Journal of cellular biochemistry20010801

Title: Podosomes in osteoclast-like cells: structural analysis and cooperative roles of paxillin, proline-rich tyrosine kinase 2 (Pyk2) and integrin alphaVbeta3.

Journal: Journal of cell science20010801

Title: Altered membrane fluidity and signal transduction in the platelets from patients of thrombotic stroke.

Journal: Molecular and cellular biochemistry20010801

Title: Integrin activation is required for VEGF and FGF receptor protein presence on human microvascular endothelial cells.

Journal: Molecular and cellular biochemistry20010801

Title: [The role of beta-catenin in the repair of the damaged airway epithelium in smoking mice].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases20010801

Title: Biochemical differences between SUDHL-1 and KARPAS 299 cells derived from t(2;5)-positive anaplastic large cell lymphoma are responsible for the different sensitivity to the antiproliferative effect of p27(Kip1).

Journal: Oncogene20010727

Title: alpha-Ketocarboxylic acid-based inhibitors of protein tyrosine phosphatases.

Journal: Bioorganic & medicinal chemistry letters20010723

Title: Role for c-Abl and p73 in the radiation response of male germ cells.

Journal: Oncogene20010719

Title: The functional interactions between CD98, beta1-integrins, and CD147 in the induction of U937 homotypic aggregation.

Journal: Blood20010715

Title: Autocatalytic tyrosine-phosphorylation of protein kinase CK2 alpha and alpha' subunits: implication of Tyr182.

Journal: The Biochemical journal20010715

Title: Differential phosphorylation of paxillin in response to surface-bound serum proteins during early osteoblast adhesion.

Journal: Biochemical and biophysical research communications20010713

Title: Thy-1 binds to integrin beta(3) on astrocytes and triggers formation of focal contact sites.

Journal: Current biology : CB20010710

Title: Human leptin signaling in human peripheral blood mononuclear cells: activation of the JAK-STAT pathway.

Journal: Cellular immunology20010710

Title: Selective insulin-induced activation of class I(A) phosphoinositide 3-kinase in PIKfyve immune complexes from 3T3-L1 adipocytes.

Journal: Molecular and cellular endocrinology20010705

Title: Alterations of the insulin-like growth factor system in patients with polycythemia vera.

Journal: Molecular and cellular endocrinology20010705

Title: Calyculin-A induces focal adhesion assembly and tyrosine phosphorylation of p125(Fak), p130(Cas), and paxillin in Swiss 3T3 cells.

Journal: Journal of cellular physiology20010701

Title: Insulin and IGF-I inhibit calcium-dependent chloride secretion by T84 human colonic epithelial cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology20010701

Title: Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family.

Journal: Clinical immunology (Orlando, Fla.)20010701

Title: SHP-1 expression by malignant small B-cell lymphomas reflects the maturation stage of their normal B-cell counterparts.

Journal: The American journal of surgical pathology20010701

Title: 18 kDa protein tyrosine phosphatase in the ocular lens.

Journal: Experimental eye research20010701

Title: The integrin, alpha6beta1, is necessary for the matrix-dependent activation of FAK and MAP kinase and the migration of human hepatocarcinoma cells.

Journal: Hepatology (Baltimore, Md.)20010701

Title: Analysis of tyrosine phosphorylation-dependent protein-protein interactions in TrkB-mediated intracellular signaling using modified yeast two-hybrid system.

Journal: Journal of biochemistry20010701

Title: PEAZ-1: a new human prostate neoplastic epithelial cell line.

Journal: The Prostate20010701

Title: Overexpression of HER-2/neu enhances the sensitivity of human bladder cancer cells to urinary isoflavones.

Journal: European journal of cancer (Oxford, England : 1990)20010701

Title: The adaptor protein shc is involved in the negative regulation of NK cell-mediated cytotoxicity.

Journal: European journal of immunology20010701

Title: Association of SLP-65/BLNK with the B cell antigen receptor through a non-ITAM tyrosine of Ig-alpha.

Journal: European journal of immunology20010701

Title: IFN-alpha and IL-18 synergistically enhance IFN-gamma production in human NK cells: differential regulation of Stat4 activation and IFN-gamma gene expression by IFN-alpha and IL-12.

Journal: European journal of immunology20010701

Title: Quadrupole time-of-flight versus triple-quadrupole mass spectrometry for the determination of phosphopeptides by precursor ion scanning.

Journal: Journal of mass spectrometry : JMS20010701

Title: Labile sulfogroup allows differentiation of sulfotyrosine and phosphotyrosine in peptides.

Journal: Journal of mass spectrometry : JMS20010701

Title: Cross talk of the interferon-alpha/beta signalling complex with gp130 for effective interleukin-6 signalling.

Journal: Genes to cells : devoted to molecular & cellular mechanisms20010701

Title: Membrane-targeting is critical for the phosphorylation of Vav2 by activated EGF receptor.

Journal: Cellular signalling20010701

Title: Src family kinase involvement in muscarinic receptor-induced tyrosine phosphorylation in differentiated SH-SY5Y cells.

Journal: Neurochemical research20010701

Title: Phosphotyrosines 627 and 659 of Gab1 constitute a bisphosphoryl tyrosine-based activation motif (BTAM) conferring binding and activation of SHP2.

Journal: The Journal of biological chemistry20010629

Title: Inhibition of the catalytic activity of cell adhesion kinase beta by protein-tyrosine phosphatase-PEST-mediated dephosphorylation.

Journal: The Journal of biological chemistry20010629

Title: Crystal structure of a complex of a type IA DNA topoisomerase with a single-stranded DNA molecule.

Journal: Nature20010628

Title: Heregulin-dependent translocation and hyperphosphorylation of ErbB-2.

Journal: Oncogene20010628

Title: Effect of H-7 on cultured human trabecular meshwork cells.

Journal: Molecular vision20010627

Title: Suppressor of cytokine signaling 1 interacts with the macrophage colony-stimulating factor receptor and negatively regulates its proliferation signal.

Journal: The Journal of biological chemistry20010622

Title: Genomic organization of the Shc-related phosphotyrosine adapters and characterization of the full-length Sck/ShcB: specific association of p68-Sck/ShcB with pp135.

Journal: Biochemical and biophysical research communications20010622

Title: Soluble E-selectin induces monocyte chemotaxis through Src family tyrosine kinases.

Journal: The Journal of biological chemistry20010615

Title: Regulation of the Src homology 2-containing inositol 5-phosphatase SHIP1 in HIP1/PDGFbeta R-transformed cells.

Journal: The Journal of biological chemistry20010615

Title: Aggretin, a heterodimeric C-type lectin from Calloselasma rhodostoma (Malayan pit viper), stimulates platelets by binding to α2β1 integrin and glycoprotein Ib, activating Syk and phospholipase Cγ 2, but does not involve the glycoprotein VI/Fc receptor γ chain collagen receptor.

Journal: The Journal of biological chemistry20010615

Title: Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade.

Journal: The Journal of biological chemistry20010615

Title: Tyrosine kinase activation by the angiotensin II receptor in the absence of calcium signaling.

Journal: The Journal of biological chemistry20010615

Title: Stat6 is necessary and sufficient for IL-4's role in Th2 differentiation and cell expansion.

Journal: Journal of immunology (Baltimore, Md. : 1950)20010615

Title: Inhibitors to the Src SH2 domain: a lesson in structure--thermodynamic correlation in drug design.

Journal: Archives of biochemistry and biophysics20010615

Title: Activation of sickle red blood cell adhesion via integrin-associated protein/CD47-induced signal transduction.

Journal: The Journal of clinical investigation20010615

Title: Differential regulation of cell migration and cell cycle progression by FAK complexes with Src, PI3K, Grb7 and Grb2 in focal contacts.

Journal: FEBS letters20010615

Title: Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition.

Journal: Cell20010615

Title: Y-27632, an inhibitor of Rho-associated kinases, prevents tyrosine phosphorylation of focal adhesion kinase and paxillin induced by bombesin: dissociation from tyrosine phosphorylation of p130(CAS).

Journal: Experimental cell research20010610

Title: IgE receptor type I-dependent tyrosine phosphorylation of phospholipid scramblase.

Journal: The Journal of biological chemistry20010608

Title: Astrocyte differentiation of fetal neuroepithelial cells involving cardiotrophin-1-induced activation of STAT3.

Journal: Cytokine20010607

Title: Tyrosine-phosphorylated low density lipoprotein receptor-related protein 1 (Lrp1) associates with the adaptor protein SHC in SRC-transformed cells.

Journal: The Journal of biological chemistry20010601

Title: Antiproliferative signaling of luteinizing hormone-releasing hormone in human endometrial and ovarian cancer cells through G protein alpha(I)-mediated activation of phosphotyrosine phosphatase.

Journal: Endocrinology20010601

Title: Stimulation by n6-cyclopentyladenosine of A1 adenosine receptors, coupled to galphai2 protein subunit, has a capacitative effect on human spermatozoa.

Journal: Biology of reproduction20010601

Title: Janus kinase 2 is involved in stromal cell-derived factor-1alpha-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells.

Journal: Blood20010601

Title: A use-dependent tyrosine dephosphorylation of NMDA receptors is independent of ion flux.

Journal: Nature neuroscience20010601

Title: TSH-induced differentiated functions correlate with enhancement of phosphotyrosine phosphatase activity in thyroid cells. Effect of phorbol 12-myristate 13-acetate.

Journal: The Journal of endocrinology20010601

Title: Subcellular localization of insulin receptor substrate family proteins associated with phosphatidylinositol 3-kinase activity and alterations in lipolysis in primary mouse adipocytes from IRS-1 null mice.

Journal: Diabetes20010601

Title: Characterization of a novel serine/threonine protein phosphatase (PfPPJ) from the malaria parasite, Plasmodium falciparum.

Journal: Molecular and biochemical parasitology20010601

Title: STAT3 is constitutively active in some patients with Polycythemia rubra vera.

Journal: Experimental hematology20010601

Title: Peroxisomal deficiencies are associated with altered activity of endothelial NOS in human fibroblasts.

Journal: Nitric oxide : biology and chemistry20010601

Title: The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway.

Journal: The EMBO journal20010601

Title: Detergent-resistant membrane domains are required for mast cell activation but dispensable for tyrosine phosphorylation upon aggregation of the high affinity receptor for IgE.

Journal: Journal of biochemistry20010601

Title: Energetic determinants of tyrosine phosphorylation of focal adhesion proteins during hypoxia/reoxygenation of kidney proximal tubules.

Journal: The American journal of pathology20010601

Title: Functional preference of the constituent amino acid residues in a phage-library-based nonphosphorylated inhibitor of the Grb2-SH2 domain.

Journal: The journal of peptide research : official journal of the American Peptide Society20010601

Title: Fingerprinting of signal transduction pathways using a combination of anti-phosphotyrosine immunoprecipitations and two-dimensional polyacrylamide gel electrophoresis.

Journal: Electrophoresis20010601

Title: Detection of tyrosine phosphorylated proteins in Trichinella spiralis L1 larvae.

Journal: Parasite (Paris, France)20010601

Title: c-Cbl ubiquitinates the EGF receptor at the plasma membrane and remains receptor associated throughout the endocytic route.

Journal: Journal of cell science20010601

Title: SHP-2 complex formation with the SHP-2 substrate-1 during C2C12 myogenesis.

Journal: Journal of cell science20010601

Title: pp60(c-src) and related tyrosine kinases: a role in the assembly and reorganization of matrix adhesions.

Journal: Journal of cell science20010601

Title: Inhibitory effect of regucalcin on protein phosphatase activity in the nuclei of rat kidney cortex.

Journal: Journal of cellular biochemistry20010601

Title: Pulling strings below the surface: hormone receptor signaling through inhibition of protein tyrosine phosphatases.

Journal: Endocrine20010601

Title: Phosphotyrosine profiling to identify novel components of interferon and interleukin 6-family cytokine signalling.

Journal: Proteomics20010601

Title: Tamoxifen interacts with NEU/C-ERBB-2 receptor and inhibits growth of human malignant glioma cell lines.

Journal: The Kobe journal of medical sciences20010601

Title: Leptin stimulates rat aortic smooth muscle cell proliferation and migration.

Journal: The Kobe journal of medical sciences20010601

Title: Pertussis toxin activates tyrosine kinase signaling cascade in myelomonocytic cells: a mechanism for cell adhesion.

Journal: Biochemical and biophysical research communications20010525

Title: Phospho-Azatyrosine, a less effective protein-tyrosine phosphatase substrate than phosphotyrosine.

Journal: Bioorganic & medicinal chemistry letters20010521

Title: The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases.

Journal: The Journal of biological chemistry20010518

Title: p110beta and p110delta phosphatidylinositol 3-kinases up-regulate Fc(epsilon)RI-activated Ca2+ influx by enhancing inositol 1,4,5-trisphosphate production.

Journal: The Journal of biological chemistry20010518

Title: Functional uncoupling of T-cell receptor engagement and Lck activation in anergic human thymic CD4+ T cells.

Journal: The Journal of biological chemistry20010518

Title: Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein.

Journal: Science (New York, N.Y.)20010518

Title: HC fragment (C-terminal portion of the heavy chain) of tetanus toxin activates protein kinase C isoforms and phosphoproteins involved in signal transduction.

Journal: The Biochemical journal20010515

Title: Caveolin-1 and a 29-kDa caveolin-associated protein are phosphorylated on tyrosine in cells expressing a temperature-sensitive v-Abl kinase.

Journal: Experimental cell research20010515

Title: Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1B and augment insulin action.

Journal: Biochemistry20010515

Title: Phosphoinositide 3-kinase modulation of beta(3)-integrin represents an endogenous 'braking' mechanism during neutrophil transmatrix migration.

Journal: Blood20010515

Title: Role of p190RhoGAP in beta 2 integrin regulation of RhoA in human neutrophils.

Journal: Journal of immunology (Baltimore, Md. : 1950)20010515

Title: c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation.

Journal: The Journal of biological chemistry20010511

Title: Identification of reelin-induced sites of tyrosyl phosphorylation on disabled 1.

Journal: The Journal of biological chemistry20010511

Title: The ERBB2/HER2 receptor differentially interacts with ERBIN and PICK1 PSD-95/DLG/ZO-1 domain proteins.

Journal: The Journal of biological chemistry20010504

Title: Mac-1-dependent tyrosine phosphorylation during neutrophil adhesion.

Journal: American journal of physiology. Cell physiology20010501

Title: TNF-alpha inhibits flow and insulin signaling leading to NO production in aortic endothelial cells.

Journal: American journal of physiology. Cell physiology20010501

Title: Protein tyrosine phosphorylation in sperm during gamete interaction in the mouse: the influence of glucose.

Journal: Biology of reproduction20010501

Title: Impact of epididymal maturation on the tyrosine phosphorylation patterns exhibited by rat spermatozoa.

Journal: Biology of reproduction20010501

Title: Pioglitazone ameliorates tumor necrosis factor-alpha-induced insulin resistance by a mechanism independent of adipogenic activity of peroxisome proliferator--activated receptor-gamma.

Journal: Diabetes20010501

Title: Insulin and leptin acutely regulate cholesterol ester metabolism in macrophages by novel signaling pathways.

Journal: Diabetes20010501

Title: Gene dosage-dependent functions for phosphotyrosine-Grb2 signaling during mammalian tissue morphogenesis.

Journal: Current biology : CB20010501

Title: Protein phosphorylation in mitochondria from human placenta.

Journal: Placenta20010501

Title: Vanadium(V) complexes in enzyme systems: aqueous chemistry, inhibition and molecular modeling in inhibitor design.

Journal: Journal of inorganic biochemistry20010501

Title: Phosphorylation of LHI beta during membrane synthesis in the photosynthetic bacterium Rhodovulum sulfidophilum.

Journal: Current microbiology20010501

Title: Histamine deficiency suppresses murine haptoglobin production and modifies hepatic protein tyrosine phosphorylation.

Journal: Cellular and molecular life sciences : CMLS20010501

Title: FcgammaRIIA exogenously expressed in HeLa cells activates the mitogen-activated protein kinase cascade by a mechanism dependent on the endogenous expression of the protein tyrosine kinase Syk.

Journal: European journal of immunology20010501

Title: Focal adhesion kinase regulates beta1 integrin-dependent T cell migration through an HEF1 effector pathway.

Journal: European journal of immunology20010501

Title: Toxoplasma gondii down-regulates MHC class II gene expression and antigen presentation by murine macrophages via interference with nuclear translocation of STAT1alpha.

Journal: European journal of immunology20010501

Title: The protein tyrosine kinase syk activity is reduced by clustering the mast cell function-associated antigen.

Journal: European journal of immunology20010501

Title: Phosphorylation and activation of protein tyrosine phosphatase (PTP) 1B by insulin receptor.

Journal: Molecular and cellular biochemistry20010501

Title: Phosphoamino acid analysis.

Journal: Current protocols in cell biology20010501

Title: Phosphoamino acid analysis.

Journal: Current protocols in molecular biology20010501

Title: Analysis of phosphorylation of unlabeled proteins.

Journal: Current protocols in molecular biology20010501

Title: Detection of phosphorylation by enzymatic techniques.

Journal: Current protocols in molecular biology20010501

Title: Production of antibodies that recognize specific tyrosine-phosphorylated peptides.

Journal: Current protocols in molecular biology20010501

Title: Phosphoamino acid analysis.

Journal: Current protocols in protein science20010501

Title: Detection of phosphorylation by immunological techniques.

Journal: Current protocols in protein science20010501

Title: Antiphosphotyrosine blotting.

Journal: Current protocols in immunology20010501

Title: The Src kinase p56(lck) up-regulates VLA-4 integrin affinity. Implications for rapid spontaneous and chemokine-triggered T cell adhesion to VCAM-1 and fibronectin.

Journal: The Journal of biological chemistry20010427

Title: Agrin-induced activation of acetylcholine receptor-bound Src family kinases requires Rapsyn and correlates with acetylcholine receptor clustering.

Journal: The Journal of biological chemistry20010427

Title: A yeast two-hybrid study of human p97/Gab2 interactions with its SH2 domain-containing binding partners.

Journal: FEBS letters20010427

Title: Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance.

Journal: Proceedings of the National Academy of Sciences of the United States of America20010424

Title: Ultraviolet radiation inhibits interleukin-2-induced tyrosine phosphorylation and the activation of STAT5 in T lymphocytes.

Journal: The Journal of biological chemistry20010420

Title: Multiple effector domains within SNT1 coordinate ERK activation and neuronal differentiation of PC12 cells.

Journal: The Journal of biological chemistry20010420

Title: Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland.

Journal: The Journal of biological chemistry20010420

Title: c-Src tyrosine kinase binds the beta 2-adrenergic receptor via phospho-Tyr-350, phosphorylates G-protein-linked receptor kinase 2, and mediates agonist-induced receptor desensitization.

Journal: The Journal of biological chemistry20010420

Title: Regulation of type II phosphatidylinositol phosphate kinase by tyrosine phosphorylation in bovine rod outer segments.

Journal: Biochemistry20010417

Title: A common epitope is shared by activated signal transducer and activator of transcription-5 (STAT5) and the phosphorylated erythropoietin receptor: implications for the docking model of STAT activation.

Journal: Blood20010415

Title: Molecular regulation of tumor cell vasculogenic mimicry by tyrosine phosphorylation: role of epithelial cell kinase (Eck/EphA2).

Journal: Cancer research20010415

Title: Carbachol stimulates TYR phosphorylation and association of PKCdelta and PYK2 in pancreas.

Journal: Biochemical and biophysical research communications20010413

Title: Electroconvulsive shock increases the phosphorylation of Pyk2 in the rat hippocampus.

Journal: Biochemical and biophysical research communications20010413

Title: The SH2 domain containing inositol 5-phosphatase SHIP2 controls phosphatidylinositol 3,4,5-trisphosphate levels in CHO-IR cells stimulated by insulin.

Journal: Biochemical and biophysical research communications20010406

Title: BCR gene expression blocks Bcr-Abl induced pathogenicity in a mouse model.

Journal: Oncogene20010405

Title: Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts.

Journal: Journal of cellular physiology20010401

Title: TNF-alpha induces protein synthesis through PI3-kinase-Akt/PKB pathway in cardiac myocytes.

Journal: American journal of physiology. Heart and circulatory physiology20010401

Title: The Bcr N-terminal oligomerization domain contributes to the full oncogenicity of P190 Bcr/Abl in transgenic mice.

Journal: International journal of molecular medicine20010401

Title: Detection of insulin receptor tyrosine kinase activity using time-resolved fluorescence energy transfer technology.

Journal: Analytical biochemistry20010401

Title: Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632.

Journal: Investigative ophthalmology & visual science20010401

Title: The role of phosphoinositide 3-kinase in spreading osteoclasts induced by colony-stimulating factor-1.

Journal: European journal of endocrinology20010401

Title: Tyrosine phosphorylation of insulin receptor substrate-1 (IRS-1) by oxidant stress in cerebellar granule neurons: modulation by N-methyl-D-aspartate through calcineurin activity.

Journal: Journal of neurochemistry20010401

Title: The clustered Fcgamma receptor II is recruited to Lyn-containing membrane domains and undergoes phosphorylation in a cholesterol-dependent manner.

Journal: European journal of immunology20010401

Title: Residues Y429 and Y463 of the human CD5 are targeted by protein tyrosine kinases.

Journal: European journal of immunology20010401

Title: Protein kinase C delta regulates neural cell adhesion molecule polysialylation state in the rat brain.

Journal: Journal of neurochemistry20010401

Title: Identification of mouse NMDA receptor subunit NR2A C-terminal tyrosine sites phosphorylated by coexpression with v-Src.

Journal: Journal of neurochemistry20010401

Title: Bivalent binding and signaling characteristics of Leridistim, a novel chimeric dual agonist of interleukin-3 and granulocyte colony-stimulating factor receptors.

Journal: Experimental hematology20010401

Title: Detection of tyrosine phosphorylated peptides by precursor ion scanning quadrupole TOF mass spectrometry in positive ion mode.

Journal: Analytical chemistry20010401

Title: Fc-receptor dependent platelet aggregation induced by monoclonal antibodies against platelet glycoprotein Ib or von Willebrand factor.

Journal: Thrombosis and haemostasis20010401

Title: Structural and functional hot spots in cytokine receptors.

Journal: International journal of hematology20010401

Title: Insulin-like effect of zinc in mytilus digestive gland cells: modulation of tyrosine kinase-mediated cell signaling.

Journal: General and comparative endocrinology20010401

Title: Engagement of endogenous ganglioside GM1a induces tyrosine phosphorylation involved in neuron-like differentiation of PC12 cells.

Journal: Glycobiology20010401

Title: The genetics of signal transduction and the effect of smoking on intrauterine growth.

Journal: International journal of epidemiology20010401

Title: Phosphorylation of prolidase increases the enzyme activity.

Journal: Molecular and cellular biochemistry20010401

Title: Natural resistance to intracellular pathogens: modulation of macrophage signal transduction related to the expression of the Bcg locus.

Journal: Proteomics20010401

Title: A novel adapter protein employs a phosphotyrosine binding domain and exceptionally basic N-terminal domains to capture and localize an atypical protein kinase C: characterization of Caenorhabditis elegans C kinase adapter 1, a protein that avidly binds protein kinase C3.

Journal: The Journal of biological chemistry20010330

Title: Structural properties and mechanisms that govern association of C kinase adapter 1 with protein kinase C3 and the cell periphery.

Journal: The Journal of biological chemistry20010330

Title: Activation of mitogen-activated protein kinases p42/44, p38, and stress-activated protein kinases in myelo-monocytic cells by Treponema lipoteichoic acid.

Journal: The Journal of biological chemistry20010330

Title: The BPS domain of Grb10 inhibits the catalytic activity of the insulin and IGF1 receptors.

Journal: FEBS letters20010330

Title: Suppression of apoptosis induced by growth factor withdrawal by an oncogenic form of c-Cbl.

Journal: The Journal of biological chemistry20010323

Title: Comparative study of protein tyrosine phosphatase-epsilon isoforms: membrane localization confers specificity in cellular signalling.

Journal: The Biochemical journal20010315

Title: Expression and purification of human recombinant GST-FGF receptor-1.

Journal: Journal of biotechnology20010309

Title: Western blotting as a method for studying cell-biomaterial interactions: the role of protein collection.

Journal: Journal of biomedical materials research20010305

Title: 17-beta estradiol elicits an autocrine leiomyoma cell proliferation: evidence for a stimulation of protein kinase-dependent pathway.

Journal: Journal of cellular physiology20010301

Title: Microglia, astrocytes, and macrophages react differentially to central and peripheral lesions in the developing and mature rat whisker-to-barrel pathway: a study using immunohistochemistry for lipocortin1, phosphotyrosine, s100 beta, and mannose receptors.

Journal: Experimental neurology20010301

Title: Impaired PI 3-kinase activation in adipocytes from early growth-restricted male rats.

Journal: American journal of physiology. Endocrinology and metabolism20010301

Title: Activation of the EBV/C3d receptor (CR2, CD21) on human B lymphocyte surface triggers tyrosine phosphorylation of the 95-kDa nucleolin and its interaction with phosphatidylinositol 3 kinase.

Journal: Journal of immunology (Baltimore, Md. : 1950)20010301

Title: Functional association of CD9 with the Fc gamma receptors in macrophages.

Journal: Journal of immunology (Baltimore, Md. : 1950)20010301

Title: Tyrosine phosphorylation-dependent activation of NF-kappa B. Requirement for p56 LCK and ZAP-70 protein tyrosine kinases.

Journal: European journal of biochemistry20010301

Title: Signal transduction activated by the cancer chemopreventive isothiocyanates: cleavage of BID protein, tyrosine phosphorylation and activation of JNK.

Journal: British journal of cancer20010301

Title: Altered autophosphorylation of the insulin receptor in the ovary of a woman with polycystic ovary syndrome.

Journal: Fertility and sterility20010301

Title: Insulin resistance with enhanced insulin signaling in high-salt diet-fed rats.

Journal: Diabetes20010301

Title: Multisite phosphotyping of the ErbB-2 oncoprotein in human breast cancer.

Journal: Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology20010301

Title: X-Ray structure of citrate bound to Src SH2 leads to a high-affinity, bone-targeted Src SH2 inhibitor.

Journal: Journal of medicinal chemistry20010301

Title: Carboxyl terminal sequence of human phospholipase Cgamma2.

Journal: Platelets20010301

Title: Capacitation-associated changes in protein tyrosine phosphorylation, hyperactivation and acrosome reaction in hamster spermatozoa.

Journal: Andrologia20010301

Title: Increased expression of iNOS and c-fos via regulation of protein tyrosine phosphorylation and MEK1/ERK2 proteins in terminal bronchiole lesions in the lungs of rats exposed to cigarette smoke.

Journal: Archives of toxicology20010301

Title: Analysis of in vitro interactions of protein tyrosine phosphatase 1B with insulin receptors.

Journal: Molecular and cellular endocrinology20010227

Title: Interleukin-4 induces two distinct GAS-binding complexes containing STAT6: evidence for DNA binding of STAT6 monomer.

Journal: Molecules and cells20010227

Title: Dexamethasone modulates TCR zeta chain expression and antigen receptor-mediated early signaling events in human T lymphocytes.

Journal: Cellular immunology20010225

Title: TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-alpha/beta dimers.

Journal: Science (New York, N.Y.)20010223

Title: G(i)-mediated Cas tyrosine phosphorylation in vascular endothelial cells stimulated with sphingosine 1-phosphate: possible involvement in cell motility enhancement in cooperation with Rho-mediated pathways.

Journal: The Journal of biological chemistry20010216

Title: The adapter type protein CMS/CD2AP binds to the proto-oncogenic protein c-Cbl through a tyrosine phosphorylation-regulated Src homology 3 domain interaction.

Journal: The Journal of biological chemistry20010216

Title: Identification of residues in the N-terminal domain of the Yersinia tyrosine phosphatase that are critical for substrate recognition.

Journal: The Journal of biological chemistry20010216

Title: Phosphatidic acid regulates tyrosine phosphorylating activity in human neutrophils: enhancement of Fgr activity.

Journal: The Journal of biological chemistry20010216

Title: Mitogen-activated protein kinase p38 mediates regulation of chondrocyte differentiation by parathyroid hormone.

Journal: The Journal of biological chemistry20010216

Title: Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development.

Journal: Blood20010215

Title: Comparison of a T cell clone and of T cells from a TCR transgenic mouse: TCR transgenic T cells specific for self-antigen are atypical.

Journal: Journal of immunology (Baltimore, Md. : 1950)20010215

Title: A model of activation of the protein tyrosine phosphatase SHP-2 by the human leptin receptor.

Journal: Biochimica et biophysica acta20010209

Title: Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages.

Journal: Current biology : CB20010206

Title: Src homology 2-containing inositol 5-phosphatase 1 binds to the multifunctional docking site of c-Met and potentiates hepatocyte growth factor-induced branching tubulogenesis.

Journal: The Journal of biological chemistry20010202

Title: Simultaneous induction of galectin-3 phosphorylated on tyrosine residue, p21(WAF1/Cip1/Sdi1), and the proliferating cell nuclear antigen at a distinctive period of repair of hepatocytes injured by CCl4.

Journal: Biochemical and biophysical research communications20010202

Title: Effects of phosphotyrosine phosphatase inhibition on insulin secretion and intracellular signaling events in rat pancreatic islets.

Journal: Biochemical and biophysical research communications20010202

Title: SHP2 and cbl participate in alpha-chemokine receptor CXCR4-mediated signaling pathways.

Journal: Blood20010201

Title: Determination of the tyrosine phosphorylation sites in the T cell transmembrane glycoprotein CD5.

Journal: International immunology20010201

Title: Distinct functions of the two protein tyrosine phosphatase domains of LAR (leukocyte common antigen-related) on tyrosine dephosphorylation of insulin receptor.

Journal: Molecular endocrinology (Baltimore, Md.)20010201

Title: Specificity of natural and artificial substrates for human Cdc25A.

Journal: Analytical biochemistry20010201

Title: Amino-terminal modification and tyrosine phosphorylation of [corrected] carboxy-terminal fragments of the amyloid precursor protein in Alzheimer's disease and Down's syndrome brain.

Journal: Neurobiology of disease20010201

Title: Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling.

Journal: The Biochemical journal20010201

Title: Nerve growth factor inhibits PC12 cell PDE 2 phosphodiesterase activity and increases PDE 2 binding to phosphoproteins.

Journal: Journal of neurochemistry20010201

Title: Insulin signal transduction in rat small intestine: role of MAP kinases in expression of mucosal hydrolases.

Journal: American journal of physiology. Gastrointestinal and liver physiology20010201

Title: Regulation of MAP kinase by calcium-sensing receptor in bovine parathyroid and CaR-transfected HEK293 cells.

Journal: American journal of physiology. Renal physiology20010201

Title: Vanadate ingestion increases the gain in wound breaking strength and leads to better organized collagen fibers in rats during healing.

Journal: Plastic and reconstructive surgery20010201

Title: Signal transduction pathways through TRK-A and TRK-B receptors in human neuroblastoma cells.

Journal: Japanese journal of cancer research : Gann20010201

Title: Long-term denervation impairs insulin receptor substrate-1-mediated insulin signaling in skeletal muscle.

Journal: Metabolism: clinical and experimental20010201

Title: Expression of the small tyrosine phosphatase (Stp1) in Saccharomyces cerevisiae: a study on protein tyrosine phosphorylation.

Journal: Electrophoresis20010201

Title: The 'early' CD4+CD8+ stage of thymocte differentiation hallmarks the end of a strong positive correlation between extracellular matrix receptor expression and protein tyrosine phosphorylation.

Journal: Cellular and molecular biology (Noisy-le-Grand, France)20010201

Title: Growth hormone induces tyrosyl phosphorylation of the transcription factors Stat5a and Stat5b in CMT-U335 canine mammary tumor cells.

Journal: Domestic animal endocrinology20010201

Title: [Effects of ischemia/reperfusion on the phosphotyrosine proteins contents in hippocampus].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology20010201

Title: Domain-dependent function of the rasGAP-binding protein p62Dok in cell signaling.

Journal: The Journal of biological chemistry20010126

Title: Phosphorylation of Wzc, a tyrosine autokinase, is essential for assembly of group 1 capsular polysaccharides in Escherichia coli.

Journal: The Journal of biological chemistry20010126

Title: Characterization of a prostate-specific tyrosine phosphatase by mutagenesis and expression in human prostate cancer cells.

Journal: The Journal of biological chemistry20010126

Title: Coupling of heterotrimeric Gi proteins to the erythropoietin receptor.

Journal: The Journal of biological chemistry20010119

Title: Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression.

Journal: The EMBO journal20010115

Title: Rhodocytin induces platelet aggregation by interacting with glycoprotein Ia/IIa (GPIa/IIa, Integrin alpha 2beta 1). Involvement of GPIa/IIa-associated src and protein tyrosine phosphorylation.

Journal: The Journal of biological chemistry20010112

Title: Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes.

Journal: The Journal of biological chemistry20010112

Title: Intramolecular interactions in protein tyrosine phosphatase RPTPmu: kinetic evidence.

Journal: Biochemical and biophysical research communications20010112

Title: Characterization of Fyn-mediated tyrosine phosphorylation sites on GluR epsilon 2 (NR2B) subunit of the N-methyl-D-aspartate receptor.

Journal: The Journal of biological chemistry20010105

Title: The addition of bisecting N-acetylglucosamine residues to E-cadherin down-regulates the tyrosine phosphorylation of beta-catenin.

Journal: The Journal of biological chemistry20010105

Title: Evidence for two distinct epitopes within collagen for activation of murine platelets.

Journal: The Journal of biological chemistry20010105

Title: Cloning protein tyrosine kinases by screening cDNA libraries with antiphosphotyrosine antibodies.

Journal: Methods in molecular biology (Clifton, N.J.)20010101

Title: Immunoprecipitation and western blotting of phosphotyrosine-containing proteins.

Journal: Methods in molecular biology (Clifton, N.J.)20010101

Title: JAK-mediated phosphorylation and activation of STAT signaling proteins. Analysis by phosphotyrosine blotting and EMSA.

Journal: Methods in molecular biology (Clifton, N.J.)20010101

Title: Detection of phosphorylation-dependent interactions by far-western gel overlay.

Journal: Methods in molecular biology (Clifton, N.J.)20010101

Title: Purification of tyrosine-phosphorylated proteins by immunoaffinity chromatography and direct cloning of their cDNAs from bacterial expression libraries.

Journal: Methods in molecular biology (Clifton, N.J.)20010101

Title: Analysis of SH2 domain--phosphopeptide interactions by isothermal titration calorimetry and surface plasmon resonance.

Journal: Methods in molecular biology (Clifton, N.J.)20010101

Title: VCAM-1 activates phosphatidylinositol 3-kinase and induces p120Cbl phosphorylation in human airway smooth muscle cells.

Journal: Journal of immunology (Baltimore, Md. : 1950)20010101

Title: Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain.

Journal: Journal of immunology (Baltimore, Md. : 1950)20010101

Title: Listeria monocytogenes modulates macrophage cytokine responses through STAT serine phosphorylation and the induction of suppressor of cytokine signaling 3.

Journal: Journal of immunology (Baltimore, Md. : 1950)20010101

Title: Distinct T cell developmental consequences in humans and mice expressing identical mutations in the DLAARN motif of ZAP-70.

Journal: Journal of immunology (Baltimore, Md. : 1950)20010101

Title: Rat seminiferous epithelium contains a unique junction (Ectoplasmic specialization) with signaling properties both of cell/cell and cell/matrix junctions.

Journal: Biology of reproduction20010101

Title: The src homology 2 domain of Bcr/Abl is required for efficient induction of chronic myeloid leukemia-like disease in mice but not for lymphoid leukemogenesis or activation of phosphatidylinositol 3-kinase.

Journal: Blood20010101

Title: The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation.

Journal: International immunology20010101

Title: Involvement of a herbimycin A-sensitive protein tyrosine kinase in extracellular action of HIV-1 Nef.

Journal: Immunology letters20010101

Title: Decreased in situ insulin receptor dephosphorylation in hyperglycemia-induced insulin resistance in rat adipocytes.

Journal: Diabetes20010101

Title: Identification of tyrosine-phosphorylated proteins associated with the nuclear envelope.

Journal: European journal of biochemistry20010101

Title: Biomarker analysis demonstrates a hypoxic environment in the castrated rat ventral prostate gland.

Journal: Journal of cellular biochemistry20010101

Title: Protein kinase C-mediated tyrosine phosphorylation of paxillin and focal adhesion kinase requires cytoskeletal integrity and is uncoupled to mitogen-activated protein kinase activation in human hepatoma cells.

Journal: Journal of biomedical science20010101

Title: Role of protein phosphorylation in the inhibition of protein synthesis caused by hypoxia in rat hepatocytes.

Journal: International journal of toxicology20010101

Title: Osmotic stress-dependent serine phosphorylation of the histidine kinase homologue DokA.

Journal: BMC biochemistry20010101

Title: Apoptosis-induction and phosphorylation state in human pancreatic carcinoma xenografts following octreotide treatment.

Journal: Anticancer research20010101

Title: Peptide library screening for determination of SH2 or phosphotyrosine-binding domain sequences.

Journal: Methods in enzymology20010101

Title: Suppressive role of endogenous regucalcin in the regulation of protein phosphatase activity in rat renal cortex cytosol.

Journal: Journal of cellular biochemistry20010101

Title: Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk.

Journal: BMC immunology20010101

Title: Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.

Journal: Biopolymers20010101

Title: Designing cell-permeant phosphopeptides to modulate intracellular signaling pathways.

Journal: Biopolymers20010101

Title: Preparation and application of antibodies to phosphoamino acid sequences.

Journal: Biopolymers20010101

Title: Tyrosine phosphorylation translocates beta-catenin from cell-->cell interface to the cytoplasm, but does not significantly enhance the LEF-1-dependent transactivating function.

Journal: Cell biology international20010101

Title: Dimerization of receptor protein-tyrosine phosphatase alpha in living cells.

Journal: BMC cell biology20010101

Title: Lovastatin controls signal transduction in vascular smooth muscle cells by modulating phosphorylation levels of mevalonate-independent pathways.

Journal: Basic research in cardiology20010101

Title: A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells.

Journal: BMC immunology20010101

Title: Lymphocyte dysmetabolism: an immunocytochemical comparative approach in IDDM and control subjects.

Journal: European journal of histochemistry : EJH20010101

Title: Mitogenic signaling by cyclic adenosine monophosphate in chromaffin cells involves phosphatidylinositol 3-kinase activation.

Journal: Journal of cellular biochemistry. Supplement20010101

Title: Interferon alpha2b increases paracellular permeability of renal proximal tubular LLC-PK1 cells via a mitogen activated protein kinase signaling pathway.

Journal: Renal failure20010101

Title: Nerve growth factor stimulates the interaction of ZIP/p62 with atypical protein kinase C and targets endosomal localization: evidence for regulation of nerve growth factor-induced differentiation.

Journal: Journal of cellular biochemistry20010101

Title: The linkage between beta1 integrin and the actin cytoskeleton is differentially regulated by tyrosine and serine/threonine phosphorylation of beta1 integrin in normal and cancerous human breast cells.

Journal: BMC cell biology20010101

Title: Protein tyrosine phosphatase activity in human endometrium.

Journal: Reproduction, fertility, and development20010101

Title: Expression of erythropoietin in human female reproductive organs.

Journal: Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia20010101

Title: Update on HER-2 as a target for cancer therapy: intracellular signaling pathways of ErbB2/HER-2 and family members.

Journal: Breast cancer research : BCR20010101

Title: Relation between the flexibility of the WPD loop and the activity of the catalytic domain of protein tyrosine phosphatase SHP-1.

Journal: Journal of cellular biochemistry20010101

Title: Grb2 dominantly associates with dynamin II in human hepatocellular carcinoma HepG2 cells.

Journal: Journal of cellular biochemistry20010101

Title: Effect of angiotensin II on protein phosphorylation in PC12 cell line.

Journal: Folia histochemica et cytobiologica20010101

Title: CD19, CD21, and CD22: multifaceted response regulators of B lymphocyte signal transduction.

Journal: International reviews of immunology20010101

Title: O-phospho-L-tyrosine protects TP53 wild-type cells against ionizing radiation.

Journal: International journal of cancer20010101

Title: v-Src-mediated phosphorylation of connexin43 on tyrosine disrupts gap junctional communication in mammalian cells.

Journal: Cell communication & adhesion20010101

Title: Phosphotyrosine Kinase Assays as a Prescreen for Inhibitors of EGFr.

Journal: Methods in molecular medicine20010101

Title: Phosphotyrosine phosphatase activity in ovarian carcinoma cells : stimulation by GnRH in plasma membrane.

Journal: Methods in molecular medicine20010101

Title: Phosphatidylinositol 4-kinase assay in ovarian carcinoma cells.

Journal: Methods in molecular medicine20010101

Title: Substrate competitive inhibitors of IGF-1 receptor kinase.

Journal: Biochemistry20001226

Title: Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product.

Journal: Biochemical and biophysical research communications20000907

Title: Structure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activity.

Journal: Proceedings of the National Academy of Sciences of the United States of America20000815

Title: Vanadium-induced kappaB-dependent transcription depends upon peroxide-induced activation of the p38 mitogen-activated protein kinase.

Journal: American journal of respiratory cell and molecular biology20000701

Title: Arsenic inhibits NF-kappaB-mediated gene transcription by blocking IkappaB kinase activity and IkappaBalpha phosphorylation and degradation.

Journal: Archives of biochemistry and biophysics20000501

Title: Altered actin cytoskeleton and inhibition of matrix metalloproteinase expression by vanadate and phenylarsine oxide, inhibitors of phosphotyrosine phosphatases: modulation of migration and invasion of human malignant glioma cells.

Journal: Molecular carcinogenesis19991201

Title: Attenuation of focal adhesion kinase signaling following depletion of agonist-sensitive pools of phosphatidylinositol 4,5-bisphosphate.

Journal: Journal of neurochemistry19991101

Title: Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in A431 cells overexpressing epidermal growth factor receptor.

Journal: British journal of pharmacology19991101

Title: Tyrosine phosphatases as targets in metal-induced signaling in human airway epithelial cells.

Journal: American journal of respiratory cell and molecular biology19990901

Title: Oxidative stress triggers STAT3 tyrosine phosphorylation and nuclear translocation in human lymphocytes.

Journal: The Journal of biological chemistry19990618

Title: The proto-oncogene p120(Cbl) is a downstream substrate of the Hck protein-tyrosine kinase.

Journal: Biochemical and biophysical research communications19990402

Title: Study on the synthesis and characterization of peptides containing phosphorylated tyrosine.

Journal: The journal of peptide research : official journal of the American Peptide Society19990201

Title: Association of Shc, Cbl, Grb2, and Sos following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin in primary rat hepatocytes.

Journal: Biochemical and biophysical research communications19981230

Title: Tumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc.

Journal: Molecular and cellular biology19980901

Title: Potent inhibition of protein-tyrosine phosphatase-1B using the phosphotyrosyl mimetic fluoro-O-malonyl tyrosine (FOMT).

Journal: Bioorganic & medicinal chemistry letters19980818

Title: Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells.

Journal: Hepatology (Baltimore, Md.)19980501

Title: Growth inhibitory effect of bovine lactoferrin to Toxoplasma gondii tachyzoites in murine macrophages: tyrosine phosphorylation in murine macrophages induced by bovine lactoferrin.

Journal: The Journal of veterinary medical science19980301

Title: Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases.

Journal: The Journal of biological chemistry19971128

Title: The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix.

Journal: Journal of virology19970601

Title: DDT stimulates c-erbB2, c-met, and STATS tyrosine phosphorylation, Grb2-Sos association, MAPK phosphorylation, and proliferation of human breast epithelial cells.

Journal: Biochemical and biophysical research communications19970203

Title: Activation of phospholipase D is tightly coupled to the phagocytosis of Mycobacterium tuberculosis or opsonized zymosan by human macrophages.

Journal: The Journal of experimental medicine19960801

Title: Dexamethasone inhibits the early steps of antigen receptor signaling in activated T lymphocytes.

Journal: Journal of immunology (Baltimore, Md. : 1950)19960615

Title: Crystal structures of the human p56lck SH2 domain in complex with two short phosphotyrosyl peptides at 1.0 A and 1.8 A resolution.

Journal: Journal of molecular biology19960301

Title: Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA.

Journal: Proceedings of the National Academy of Sciences of the United States of America19960109

Title: The catalytic subunit of phosphatidylinositol 3-kinase is a substrate for the activated platelet-derived growth factor receptor, but not for middle-T antigen-pp60c-src complexes.

Journal: The Biochemical journal19940801

Title: Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.

Journal: Molecular and cellular biology19940301

Title: Efficient Fmoc/solid-phase peptide synthesis of O-phosphotyrosyl-containing peptides and their use as phosphatase substrates.

Journal: International journal of peptide and protein research19940101

Title: Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain.

Journal: Proceedings of the National Academy of Sciences of the United States of America19931201

Title: Fatty acid-binding protein from rat heart is phosphorylated on Tyr19 in response to insulin stimulation.

Journal: Journal of lipid research19930801

Title: Alterations in the subcellular distribution of p21ras-GTPase activating protein in proliferating rat acinar cells.

Journal: Biochemical and biophysical research communications19920916

Title: Efficient solid phase synthesis of mixed Thr(P)-, Ser(P)- and Tyr(P)-containing phosphopeptides by 'global' 'phosphite-triester' phosphorylation.

Journal: International journal of peptide and protein research19920801

Title: Fmoc/solid-phase synthesis of Tyr(P)-containing peptides through t-butyl phosphate protection.

Journal: International journal of peptide and protein research19910601

Title: Phosphotyrosine as a specificity determinant for casein kinase-2, a growth related Ser/Thr-specific protein kinase.

Journal: FEBS letters19910225

Title: Phosphorylation of src-phosphopeptides by casein kinases-1 and -2: favourable effect of phosphotyrosine.

Journal: Biochemical and biophysical research communications19900731

Title: Effect of vanadate on the cellular accumulation of pp15, an apparent product of insulin receptor tyrosine kinase action.

Journal: The Journal of biological chemistry19880925

Title: Partial purification and characterization of phosphotyrosyl-protein phosphatase(s) from human erythrocyte cytosol.

Journal: Biochemical and biophysical research communications19860529

Title: Rapid estradiol/ERalpha signaling enhances aromatase enzymatic activity in breast cancer cells.

Journal: Molecular endocrinology (Baltimore, Md.)

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