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84-69-5,MFCD00026480
Catalog No.:AA003TON

84-69-5 | Phthalic Acid Diisobutyl Ester

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5g
98%(GC)
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$24.00   $17.00
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25g
>98.0%(GC)
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$27.00   $19.00
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500g
>98.0%(GC)
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003TON
Chemical Name:
Phthalic Acid Diisobutyl Ester
CAS Number:
84-69-5
Molecular Formula:
C16H22O4
Molecular Weight:
278.3435
MDL Number:
MFCD00026480
SMILES:
CC(COC(=O)c1ccccc1C(=O)OCC(C)C)C
NSC Number:
15316
Properties
Properties
 
BP:
296.0°C  
Form:
Liquid  
MP:
-64 °C  
Refractive Index:
n20/D 1.49(lit.)  
Storage:
Room Temperature;Keep in dry area;  

Computed Properties
 
Complexity:
290  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
8  
XLogP3:
4.1  

Literature

Title: Transcriptomic and phenotypic profiling in developing zebrafish exposed to thyroid hormone receptor agonists.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20180401

Title: Peroxisome proliferator activated receptor gamma in human placenta may mediate the adverse effects of phthalates exposure in pregnancy.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20180101

Title: Evaluation of the effects of α-cypermethrin on fetal rat testicular steroidogenesis.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20170901

Title: Agonistic and antagonistic effects of phthalates and their urinary metabolites on the steroid hormone receptors ERα, ERβ, and AR.

Journal: Toxicology letters 20170805

Title: Effects of an Environmentally Relevant Phthalate Mixture on Cultured Mouse Antral Follicles.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170301

Title: Screening of endocrine activity of compounds migrating from plastic baby bottles using a multi-receptor panel of in vitro bioassays.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20161201

Title: Activation of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) by Semi-Volatile Compounds (SVOCs) and Chemical Mixtures in Indoor Dust.

Journal: Environmental science & technology 20150818

Title: Structure-dependent activity of phthalate esters and phthalate monoesters binding to human constitutive androstane receptor.

Journal: Chemical research in toxicology 20150615

Title: Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150201

Title: Associations of filaggrin gene loss-of-function variants with urinary phthalate metabolites and testicular function in young Danish Men.

Journal: Environmental health perspectives 20140401

Title: Phthalate levels in cord blood are associated with preterm delivery and fetal growth parameters in Chinese women.

Journal: PloS one 20140101

Title: Evaluation of a screening system for obesogenic compounds: screening of endocrine disrupting compounds and evaluation of the PPAR dependency of the effect.

Journal: PloS one 20130101

Title: Effect of cooking at home on the levels of eight phthalates in foods.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121201

Title: Phthalates dietary exposure and food sources for Belgian preschool children and adults.

Journal: Environment international 20121101

Title: Simultaneous determination of 17 phthalate esters in edible vegetable oils by GC-MS with silica/PSA-mixed solid-phase extraction.

Journal: Journal of separation science 20121101

Title: Study on chemical composition, anti-inflammatory and anti-microbial activities of extracts from Chinese pear fruit (Pyrus bretschneideri Rehd.).

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121001

Title: Risk assessment of human exposure to bioaccessible phthalate esters via indoor dust around the Pearl River Delta.

Journal: Environmental science & technology 20120807

Title: Characteristics and assessment of phthalate esters in urban dusts in Guangzhou city, China.

Journal: Environmental monitoring and assessment 20120801

Title: Phthalates in Belgian cow's milk and the role of feed and other contamination pathways at farm level.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120801

Title: Analysis of phthalates in food products and packaging materials sold on the Belgian market.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120701

Title: Cumulative risk assessment of phthalate exposure of Danish children and adolescents using the hazard index approach.

Journal: International journal of andrology 20120601

Title: Air-assisted liquid-liquid microextraction method as a novel microextraction technique; application in extraction and preconcentration of phthalate esters in aqueous sample followed by gas chromatography-flame ionization detection.

Journal: Analytica chimica acta 20120530

Title: Do interactions between gut ecology and environmental chemicals contribute to obesity and diabetes?

Journal: Environmental health perspectives 20120301

Title: Determination of phthalate esters in cow milk samples using dispersive liquid-liquid microextraction coupled with gas chromatography followed by flame ionization and mass spectrometric detection.

Journal: Journal of separation science 20120301

Title: [Simultaneous determination of 19 phthalate esters in cosmetics using gas chromatography-mass spectrometry].

Journal: Se pu = Chinese journal of chromatography 20120301

Title: Occurrence of thyroid hormone activities in drinking water from eastern China: contributions of phthalate esters.

Journal: Environmental science & technology 20120207

Title: In situ ATR-FTIR studies on MgCl2-diisobutyl phthalate interactions in thin film Ziegler-Natta catalysts.

Journal: Langmuir : the ACS journal of surfaces and colloids 20120207

Title: Maternal prenatal urinary phthalate metabolite concentrations and child mental, psychomotor, and behavioral development at 3 years of age.

Journal: Environmental health perspectives 20120201

Title: Genomic biomarkers of phthalate-induced male reproductive developmental toxicity: a targeted RT-PCR array approach for defining relative potency.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120201

Title: Dual field nonlinear dielectric spectroscopy in a glass forming EPON 828 epoxy resin.

Journal: Journal of physics. Condensed matter : an Institute of Physics journal 20120125

Title: [Survey of plasticizers in polyvinyl chloride toys].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20120101

Title: Determination of phthalic acid diesters in human milk at low ppb levels.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101

Title: Toxicologically relevant phthalates in food.

Journal: EXS 20120101

Title: Ovarian development in Wistar rat treated prenatally with single dose diisobutyl phthalate.

Journal: Bratislavske lekarske listy 20120101

Title: Trends of the internal phthalate exposure of young adults in Germany--follow-up of a retrospective human biomonitoring study.

Journal: International journal of hygiene and environmental health 20111201

Title: Dose-response assessment of fetal testosterone production and gene expression levels in rat testes following in utero exposure to diethylhexyl phthalate, diisobutyl phthalate, diisoheptyl phthalate, and diisononyl phthalate.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110901

Title: Beyond phthalates: gas phase concentrations and modeled gas/particle distribution of modern plasticizers.

Journal: The Science of the total environment 20110901

Title: Exposure to phthalates in 5-6 years old primary school starters in Germany--a human biomonitoring study and a cumulative risk assessment.

Journal: International journal of hygiene and environmental health 20110601

Title: Phthalates and their metabolites in breast milk--results from the Bavarian Monitoring of Breast Milk (BAMBI).

Journal: Environment international 20110501

Title: Comparative assessment of human exposure to phthalate esters from house dust in China and the United States.

Journal: Environmental science & technology 20110415

Title: Many putative endocrine disruptors inhibit prostaglandin synthesis.

Journal: Environmental health perspectives 20110401

Title: Selective phthalate activation of naturally occurring human constitutive androstane receptor splice variants and the pregnane X receptor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110401

Title: Phthalates in cosmetic and personal care products: concentrations and possible dermal exposure.

Journal: Environmental research 20110401

Title: Preparation of polypyrrole-coated magnetic particles for micro solid-phase extraction of phthalates in water by gas chromatography-mass spectrometry analysis.

Journal: Journal of chromatography. A 20110325

Title: Phthalate exposure in pregnant women and their children in central Taiwan.

Journal: Chemosphere 20110201

Title: Exposure to phthalates among premenstrual girls from rural and urban Gharbiah, Egypt: a pilot exposure assessment study.

Journal: Environmental health : a global access science source 20110101

Title: [Chemical constituents from roots of Pueraria lobata].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101201

Title: α-Glucosidase inhibition and the in vivo hypoglycemic effect of butyl-isobutyl-phthalate derived from the Laminaria japonica rhizoid.

Journal: Phytotherapy research : PTR 20101101

Title: Consumer exposure to phthalates from paper packaging: an integrated approach.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20101001

Title: Semivolatile endocrine-disrupting compounds in paired indoor and outdoor air in two northern California communities.

Journal: Environmental science & technology 20100901

Title: [Effect of diisobutyl phthalate on antioxidase activity and DNA damage in mice].

Journal: Wei sheng yan jiu = Journal of hygiene research 20100901

Title: Dietary intake is associated with phthalate body burden in a nationally representative sample.

Journal: Environmental health perspectives 20100701

Title: Influence of a five-day vegetarian diet on urinary levels of antibiotics and phthalate metabolites: a pilot study with 'Temple Stay' participants.

Journal: Environmental research 20100501

Title: Polyethylene terephthalate may yield endocrine disruptors.

Journal: Environmental health perspectives 20100401

Title: Exposure to phthalates and breast cancer risk in northern Mexico.

Journal: Environmental health perspectives 20100401

Title: Transcriptional biomarkers of steroidogenesis and trophoblast differentiation in the placenta in relation to prenatal phthalate exposure.

Journal: Environmental health perspectives 20100201

Title: [Distribution characteristics of phthalic acid esters in soils and plants at e-waste recycling sites in Taizhou of Zhejiang, China].

Journal: Ying yong sheng tai xue bao = The journal of applied ecology 20100201

Title: Effects of di-iso-butyl phthalate on testes of prepubertal rats and mice.

Journal: Okajimas folia anatomica Japonica 20100201

Title: Distribution of phthalate esters in alluvial sediment: a case study at JiangHan Plain, Central China.

Journal: Chemosphere 20100101

Title: Effect of asafoetida extract on growth and quality of Pleurotus ferulic.

Journal: International journal of molecular sciences 20100101

Title: PPARs and xenobiotic-induced adverse effects: relevance to human health.

Journal: PPAR research 20100101

Title: Analysis and migration of phthalates in infant food packed in recycled paperboard.

Journal: Journal of agricultural and food chemistry 20091125

Title: Urinary phthalate metabolites in relation to preterm birth in Mexico city.

Journal: Environmental health perspectives 20091001

Title: Seasonal distribution of phthalate esters in surface water of the urban lakes in the subtropical city, Guangzhou, China.

Journal: Journal of hazardous materials 20090930

Title: Fetal exposure to phthalates--a pilot study.

Journal: International journal of hygiene and environmental health 20090901

Title: Cell death and production of reactive oxygen species by murine macrophages after short term exposure to phthalates.

Journal: Toxicology letters 20090724

Title: Determination of total and free mono-n-butyl phthalate in human urine samples after medication of a di-n-butyl phthalate containing capsule.

Journal: Toxicology letters 20090710

Title: A two-component female-produced pheromone of the spider Pholcus beijingensis.

Journal: Journal of chemical ecology 20090701

Title: [Antifungal sctivities and stability of extracts from culture liquid of Hypoxylon perforatum to Sphaeropsis sapinea].

Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20090701

Title: Distribution of phthalate esters in urban soils of subtropical city, Guangzhou, China.

Journal: Journal of hazardous materials 20090530

Title: Hazard to the developing male reproductive system from cumulative exposure to phthalate esters--dibutyl phthalate, diisobutyl phthalate, butylbenzyl phthalate, diethylhexyl phthalate, dipentyl phthalate, and diisononyl phthalate.

Journal: Regulatory toxicology and pharmacology : RTP 20090301

Title: Lactational exposure to phthalates in Southern Italy.

Journal: Environment international 20090201

Title: Urinary phthalate metabolite concentrations among workers in selected industries: a pilot biomonitoring study.

Journal: The Annals of occupational hygiene 20090101

Title: Genetic and environmental pathways to complex diseases.

Journal: BMC systems biology 20090101

Title: Analysis of di-n-butyl phthalate and other organic pollutants in Chongqing women undergoing parturition.

Journal: Environmental pollution (Barking, Essex : 1987) 20081201

Title: Phthalate esters (PAEs): emerging organic contaminants in agricultural soils in peri-urban areas around Guangzhou, China.

Journal: Environmental pollution (Barking, Essex : 1987) 20081101

Title: A controlled challenge study on di(2-ethylhexyl) phthalate (DEHP) in house dust and the immune response in human nasal mucosa of allergic subjects.

Journal: Environmental health perspectives 20081101

Title: Diisobutyl phthalate impairs the androgen-dependent reproductive development of the male rat.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20081001

Title: Impact of diisobutyl phthalate and other PPAR agonists on steroidogenesis and plasma insulin and leptin levels in fetal rats.

Journal: Toxicology 20080904

Title: A mixture of five phthalate esters inhibits fetal testicular testosterone production in the sprague-dawley rat in a cumulative, dose-additive manner.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080901

Title: The role of exposure to phthalates from polyvinyl chloride products in the development of asthma and allergies: a systematic review and meta-analysis.

Journal: Environmental health perspectives 20080701

Title: Phthalates: metabolism and exposure.

Journal: International journal of andrology 20080401

Title: Assessing human exposure to phthalic acid and phthalate esters from mineral water stored in polyethylene terephthalate and glass bottles.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20080401

Title: Characterization of phthalate exposure among pregnant women assessed by repeat air and urine samples.

Journal: Environmental health perspectives 20080401

Title: Determination of phthalates and adipate in bottled water by headspace solid-phase microextraction and gas chromatography/mass spectrometry.

Journal: Journal of chromatography. A 20080118

Title: Migration of organic compounds from a multilayer plastic-paper material intended for food packaging.

Journal: Analytical and bioanalytical chemistry 20070901

Title: Direct oxidation of n-heptane to ester over modified sulfated SnO2 catalysts under mild conditions.

Journal: Journal of hazardous materials 20070825

Title: Occurrence and air-sea exchange of phthalates in the Arctic.

Journal: Environmental science & technology 20070701

Title: Reliability of fibres in solid-phase microextraction for routine analysis of the headspace of aromatic and medicinal plants.

Journal: Journal of chromatography. A 20070608

Title: Internal phthalate exposure over the last two decades--a retrospective human biomonitoring study.

Journal: International journal of hygiene and environmental health 20070501

Title: Diisobutyl phthalate degradation by Fenton treatment.

Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20070401

Title: Glass transition dynamics and boiling temperatures of molecular liquids and their isomers.

Journal: The journal of physical chemistry. B 20070329

Title: [Simultaneous determination of phthalates and parabens in cosmetic products by gas chromatography/mass spectrometry coupled with solid phase extraction].

Journal: Se pu = Chinese journal of chromatography 20070301

Title: Pilot study of urinary biomarkers of phytoestrogens, phthalates, and phenols in girls.

Journal: Environmental health perspectives 20070101

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: Developmental toxic effects of diisobutyl phthalate, the methyl-branched analogue of di-n-butyl phthalate, administered by gavage to rats.

Journal: Toxicology letters 20060801

Title: Diisobutyl phthalate has comparable anti-androgenic effects to di-n-butyl phthalate in fetal rat testis.

Journal: Toxicology letters 20060601

Title: Estimated daily phthalate exposures in a population of mothers of male infants exhibiting reduced anogenital distance.

Journal: Environmental health perspectives 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: [GC-MS analysis of the fatty components of pollen Typhae before and after being carbonized].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060201

Title: [Levels of selected organochlorine insecticides, polychlorinated biphenyls, phthalates and perfluorinated aliphatic substances in blood--Polish WWF study].

Journal: Roczniki Panstwowego Zakladu Higieny 20060101

Title: Occurrence of endocrine-disrupting compounds in reclaimed water from Tianjin, China.

Journal: Analytical and bioanalytical chemistry 20051101

Title: Phthalates in indoor dust and their association with building characteristics.

Journal: Environmental health perspectives 20051001

Title: Differential effects of phthalate esters on transcriptional activities via human estrogen receptors alpha and beta, and androgen receptor.

Journal: Toxicology 20050601

Title: Simultaneous screening and determination eight phthalates in plastic products for food use by sonication-assisted extraction/GC-MS methods.

Journal: Talanta 20050430

Title: [Chemical constituents from marine alga Chaetomorpha basiretorsa].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050301

Title: Automated solid-phase extraction and quantitative analysis of 14 phthalate metabolites in human serum using isotope dilution-high-performance liquid chromatography-tandem mass spectrometry.

Journal: Journal of analytical toxicology 20050101

Title: The association between asthma and allergic symptoms in children and phthalates in house dust: a nested case-control study.

Journal: Environmental health perspectives 20041001

Title: Pesticide and plasticizer residues in bergamot essential oils from Calabria (Italy).

Journal: Chemosphere 20040801

Title: Prenatal exposures to phthalates among women in New York City and Krakow, Poland.

Journal: Environmental health perspectives 20031101

Title: Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.

Journal: Chemical research in toxicology 20031001

Title: Supercritical fluid extraction of potential migrants from paper and board intended for use as food packaging materials.

Journal: Analytical chemistry 20021115

Title: Phthalate esters detected in various water samples and biodegradation of the phthalates by microbes isolated from river water.

Journal: Biological & pharmaceutical bulletin 20020201

Title: Production process contamination of citrus essential oils by plastic materials.

Journal: Journal of agricultural and food chemistry 20010801

Title: [Genotoxicity of phthalates. On the discussion of plasticizers in children's toys].

Journal: HNO 20010501

Title: Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens.

Journal: Chemical research in toxicology 20010301

Title: Determination of phthalates in crude extracts of sewage sludges by high-resolution capillary gas chromatography with mass spectrometric detection.

Journal: Journal of AOAC International 20010101

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Tags:84-69-5 Molecular Formula|84-69-5 MDL|84-69-5 SMILES|84-69-5 Phthalic Acid Diisobutyl Ester |Organic_Building_Blocks