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1660-95-3,MFCD00015021
Catalog No.:AA003UMN

1660-95-3 | Tetraisopropyl methylenediphosphonate

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1g
98%
in stock  
$6.00   $4.00
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5g
98%
in stock  
$8.00   $6.00
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25g
98%
in stock  
$28.00   $20.00
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100g
98%
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$111.00   $78.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003UMN
Chemical Name:
Tetraisopropyl methylenediphosphonate
CAS Number:
1660-95-3
Molecular Formula:
C13H30O6P2
Molecular Weight:
344.3212
MDL Number:
MFCD00015021
SMILES:
CC(OP(=O)(CP(=O)(OC(C)C)OC(C)C)OC(C)C)C
NSC Number:
226577
Properties
Properties
 
BP:
155°C at 0.5 mmHg  
Form:
Solid  
Refractive Index:
n20/D 1.431(lit.)  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
328  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
6  
Rotatable Bond Count:
10  
XLogP3:
2  

Downstream Synthesis Route

[1]Menge;Muenzenberg;Reimann[ArchivderPharmazie,1981,vol.314,#3,p.218-222]

[2]Hays,H.R.;Logan,T.J.[JournalofOrganicChemistry,1966,vol.31,p.3391-3394]

1660-95-3    111-83-1   
nonyl1,1-diphosphonicacidtetraisopropylester 

[1]Hays,H.R.;Logan,T.J.[JournalofOrganicChemistry,1966,vol.31,p.3391-3394]

[2]CurrentPatentAssignee:TSINGHUAUNIVERSITY(CHINA)-CN107163078,2017,ALocationinpatent:Paragraph0107;0108

[1]Mohamady,Samy;Jakeman,DavidL.[JournalofOrganicChemistry,2005,vol.70,#25,p.10588-10591]

[2]Quimby,O.T.etal.[JournalofOrganometallicChemistry,1968,vol.13,p.199-207]

[3]Oertell,Keriann;Chamberlain,BrianT.;Wu,Yue;Ferri,Elena;Kashemirov,BorisA.;Beard,WilliamA.;Wilson,SamuelH.;McKenna,CharlesE.;Goodman,MyronF.[Biochemistry,2014,vol.53,#11,p.1842-1848]

[1]Nuretdinov,I.A.;Gubskaya,V.P.;Shishikina,N.I.;Fazleeva,G.M.;Berezhnaya,L.Sh.;Karaseva,I.P.;Sibgatullina,F.G.;Zverev,V.V.[RussianChemicalBulletin,2002,vol.51,#2,p.337-341][IzvestiyaAkademiNauk,SeriyaKhimicheskaya,2002,#2,p.317-320]

[2]Quimby,O.T.etal.[JournalofOrganometallicChemistry,1968,vol.13,p.199-207]

[3]Hutchinson,DavidW.;Semple,Graeme[JournalofOrganometallicChemistry,1985,vol.291,p.145-152]

[4]McKenna,CharlesE.;Khawli,LeslieA.;Ahmad,Wan-Yaacob;Pham,Phuong;Bongartz,Jean-Pierre[PhosphorusandSulfurandtheRelatedElements,1988,vol.37,p.1-12]

[1]Thorarinsdottir,AgnesE.;Du,Kang;Collins,JamesH.P.;Harris,T.David[JournaloftheAmericanChemicalSociety,2017,vol.139,#44,p.15836-15847]

[2]McKenna,CharlesE.;Khawli,LeslieA.;Ahmad,Wan-Yaacob;Pham,Phuong;Bongartz,Jean-Pierre[PhosphorusandSulfurandtheRelatedElements,1988,vol.37,p.1-12]

[3]Hutchinson,DavidW.;Semple,Graeme[JournalofOrganometallicChemistry,1985,vol.291,p.145-152]

[4]Quimby,O.T.etal.[JournalofOrganometallicChemistry,1968,vol.13,p.199-207]

[5]Oertell,Keriann;Chamberlain,BrianT.;Wu,Yue;Ferri,Elena;Kashemirov,BorisA.;Beard,WilliamA.;Wilson,SamuelH.;McKenna,CharlesE.;Goodman,MyronF.[Biochemistry,2014,vol.53,#11,p.1842-1848]

[6]Yanachkov,IvanB.;Chang,Hung;Yanachkova,MilkaI.;Dix,EdwardJ.;Berny-Lang,MichelleA.;Gremmel,Thomas;Michelson,AlanD.;Wright,GeorgeE.;Frelinger,AndrewL.[EuropeanJournalofMedicinalChemistry,2016,vol.107,p.204-218]

[7]Malwal,SatishR.;O'Dowd,Bing;Feng,Xinxin;Turhanen,Petri;Shin,Christopher;Yao,Jiaqi;Kim,BooKyung;Baig,Noman;Zhou,Tianhui;Bansal,Sandhya;Khade,RahulL.;Zhang,Yong;Oldfield,Eric[JournaloftheAmericanChemicalSociety,2018,vol.140,#24,p.7568-7578]

Literature

Title: Phosphorus stabilized carbene complexes: bisphosphonate dianion synthesis, reactivity and DFT studies of O~C~O zirconium(IV) complexes.

Journal: Dalton transactions (Cambridge, England : 2003) 20100114

Title: Some phosphonic acid analogs as inhibitors of pyrophosphate-dependent phosphofructokinase, a novel target in Toxoplasma gondii.

Journal: Biochemical pharmacology 19950106

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