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6100-05-6,MFCD00036362
Catalog No.:AA003TT9

6100-05-6 | Potassium citrate monohydrate

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25g
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$24.00   $17.00
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100g
99%
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500g
≥99 %
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003TT9
Chemical Name:
Potassium citrate monohydrate
CAS Number:
6100-05-6
Molecular Formula:
C6H7K3O8
Molecular Weight:
324.4099
MDL Number:
MFCD00036362
SMILES:
[O-]C(=O)C(CC(=O)[O-])(CC(=O)[O-])O.[K+].[K+].[K+].O
Properties
Properties
 
Form:
Solid  
MP:
275 °C (dec.)(lit.)  
Solubility:
H2O: 1 M at 20 °C, clear, colorless  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
211  
Covalently-Bonded Unit Count:
5  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  

Literature

Title: Cystinuria: mechanisms and management.

Journal: Pediatric nephrology (Berlin, Germany) 20121101

Title: Correction of metabolic acidosis with potassium citrate in renal transplant patients and its effect on bone quality.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20120907

Title: Role of combined use of potassium citrate and tamsulosin in the management of uric acid distal ureteral calculi.

Journal: Urological research 20120601

Title: Effects of the association of potassium citrate and agropyrum repens in renal stone treatment: results of a prospective randomized comparison with potassium citrate.

Journal: Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 20120601

Title: A comparative pilot study of litholytic properties of Celosia argental (Sitivaraka) versus potassium citrate in renal calculus disease.

Journal: Journal of alternative and complementary medicine (New York, N.Y.) 20120501

Title: Primary hyperoxaluria Type 1: indications for screening and guidance for diagnosis and treatment.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120501

Title: Melamine-induced urolithiasis in a Drosophila model.

Journal: Journal of agricultural and food chemistry 20120314

Title: Nerve-targeted desensitizing toothpastes occlude dentin tubules and induce mineral precipitation.

Journal: American journal of dentistry 20120201

Title: The effects of the hydroalcohol extract of Rosa canina L. fruit on experimentally nephrolithiasic Wistar rats.

Journal: Phytotherapy research : PTR 20120101

Title: Biochemical control of bone loss and stone-forming propensity by potassium-calcium citrate after bariatric surgery.

Journal: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 20120101

Title: Longitudinal study of bone mineral density in children with idiopathic hypercalciuria.

Journal: Pediatric nephrology (Berlin, Germany) 20120101

Title: Effect of dietary supplements in reducing probability of death for uremic crises in dogs affected by chronic kidney disease (masked RCCT).

Journal: TheScientificWorldJournal 20120101

Title: Hypercalciuria associated with high dietary protein intake is not due to acid load.

Journal: The Journal of clinical endocrinology and metabolism 20111201

Title: Dietary modifications alone do not improve bone mineral density in children with idiopathic hypercalciuria.

Journal: Clinical nephrology 20111101

Title: Fanconi-Bickel syndrome in a 3-year-old Indian boy with a novel mutation in the GLUT2 gene.

Journal: Clinical and experimental nephrology 20111001

Title: Attending rounds: patient with hypokalemia and metabolic acidosis.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20111001

Title: EPR and optical studies of vanadium doped potassium dihydrogen citrate (C6H7KO7) single crystal.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110901

Title: Splenda® improves tolerance of oral potassium citrate supplementation for prevention of stone formation: results of a randomized double-blind trial.

Journal: Journal of endourology 20110901

Title: Ethylene glycol induces calcium oxalate crystal deposition in Malpighian tubules: a Drosophila model for nephrolithiasis/urolithiasis.

Journal: Kidney international 20110801

Title: Re: Strategy to control catheter encrustation with citrated drinks: a randomized crossover study. A. Khan, F. Housami, R. Melotti, A. Timoney and D. Stickler. J Urol 2010; 183: 1390-1394.

Journal: The Journal of urology 20110501

Title: [Comparison of a new medical device with domperidone in functional dyspepsia: a randomized, cross-over, controlled study].

Journal: Minerva medica 20110401

Title: [A clinical study on the effectiveness of desensitizing toothpaste in patients with dentine hypersensitivity].

Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20110218

Title: Nephrolithiasis-associated bone disease: pathogenesis and treatment options.

Journal: Kidney international 20110201

Title: Alkaline citrate reduces stone recurrence and regrowth after shockwave lithotripsy and percutaneous nephrolithotomy.

Journal: International braz j urol : official journal of the Brazilian Society of Urology 20110101

Title: Long-term treatment of renal lithiasis with potassium citrate.

Journal: Urology 20101201

Title: Pregnancy predisposes to rhabdomyolysis due to hypokalemia.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20101101

Title: Long-term treatment with potassium citrate and renal stones in medullary sponge kidney.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20100901

Title: Acute renal failure due to bilateral pieloureteral stone impaction in a 10-month-old boy.

Journal: Clinical and experimental nephrology 20100801

Title: Medullary sponge kidney: causes and treatments.

Journal: British journal of nursing (Mark Allen Publishing) 20100801

Title: Familial distal renal tubular acidosis presenting as acute quadriparesis.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20100701

Title: Effect of blind treatment on stone disease.

Journal: Urological research 20100601

Title: Effect of disaccharides on ion properties in milk-based systems.

Journal: Journal of agricultural and food chemistry 20100526

Title: Litholytic property of Kulattha (Dolichous biflorus) vs potassium citrate in renal calculus disease: a comparative study.

Journal: The Journal of the Association of Physicians of India 20100501

Title: Strategy to control catheter encrustation with citrated drinks: a randomized crossover study.

Journal: The Journal of urology 20100401

Title: Update on the pathophysiology and management of uric acid renal stones.

Journal: Current rheumatology reports 20100401

Title: Preventive effect of commercial desensitizing toothpastes on bovine enamel erosion in vitro.

Journal: Caries research 20100101

Title: [Humidity as a necessary condition for latent fingerprint detection with ninhydrin--a practice-oriented and inexpensive method using potassium citrate].

Journal: Archiv fur Kriminologie 20100101

Title: Bone disease in medullary sponge kidney and effect of potassium citrate treatment.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20091201

Title: Medical treatment of pediatric urolithiasis.

Journal: Pediatric nephrology (Berlin, Germany) 20091101

Title: Acute effects of calcium carbonate, calcium citrate and potassium citrate on markers of calcium and bone metabolism in young women.

Journal: The British journal of nutrition 20091101

Title: Effect of potassium citrate therapy on the risk of renal stone formation during spaceflight.

Journal: The Journal of urology 20091101

Title: Isolation of caseins from whey proteins by microfiltration modifying the mineral balance in skim milk.

Journal: Journal of dairy science 20091101

Title: Urinary citrate and renal stone disease: the preventive role of alkali citrate treatment.

Journal: Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 20090901

Title: Dissolution of radiolucent renal stones by oral alkalinization with potassium citrate/potassium bicarbonate.

Journal: Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 20090901

Title: Empiric use of potassium citrate reduces kidney-stone incidence with the ketogenic diet.

Journal: Pediatrics 20090801

Title: Tablets of the potassium citrate may cause a stone-like image: a case report.

Journal: Urological research 20090601

Title: Impact of long-term potassium citrate therapy on urinary profiles and recurrent stone formation.

Journal: The Journal of urology 20090301

Title: Hyperkalaemic cardiac arrhythmia due to prolonged ingestion of potassium citrate.

Journal: International journal of cardiology 20090124

Title: Urine pH in renal calcium stone formers who do and do not increase stone phosphate content with time.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090101

Title: Can lemon juice be an alternative to potassium citrate in the treatment of urinary calcium stones in patients with hypocitraturia? A prospective randomized study.

Journal: Urological research 20081201

Title: Effects of urine pH modification on pharmacokinetics of phenobarbital in healthy dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20081001

Title: Medical stone management: 35 years of advances.

Journal: The Journal of urology 20080901

Title: A new method for plasma citrate determination by reversed-phase high-performance liquid chromatography after ultrafiltration extraction: an example for bioequivalence evaluation of a medicinal endogenous substance.

Journal: Methods and findings in experimental and clinical pharmacology 20080901

Title: Acetazolamide is an effective adjunct for urinary alkalization in patients with uric acid and cystine stone formation recalcitrant to potassium citrate.

Journal: Urology 20080801

Title: Citraturic, alkalinizing and antioxidative effects of limeade-based regimen in nephrolithiasis patients.

Journal: Urological research 20080801

Title: The effect of a dietary supplement of potassium chloride or potassium citrate on blood pressure in predominantly normotensive volunteers.

Journal: The British journal of nutrition 20080601

Title: Effect of potassium citrate salts on the vapor-liquid equilibrium properties of aqueous solutions of alanine at different temperatures.

Journal: Biophysical chemistry 20080601

Title: Practical approach to metabolic evaluation and treatment of the recurrent stone patient.

Journal: WMJ : official publication of the State Medical Society of Wisconsin 20080401

Title: Prevention of shockwave induced functional and morphological alterations: an overview.

Journal: Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 20080301

Title: Potassium may help fight osteoporosis. Potassium citrate increases bone-beneficial calcium retention.

Journal: DukeMedicine healthnews 20080101

Title: [EMIL - A new formula to help the pregnant woman].

Journal: Akusherstvo i ginekologiia 20080101

Title: Cystinuria in children and young adults: success of monitoring free-cystine urine levels.

Journal: Pediatric nephrology (Berlin, Germany) 20071101

Title: Lemonade therapy increases urinary citrate and urine volumes in patients with recurrent calcium oxalate stone formation.

Journal: Urology 20071101

Title: Urinary citrate levels do not correlate with urinary pH in patients with urinary stone formation.

Journal: Urology 20071001

Title: Circadian variation in urine pH and uric acid nephrolithiasis risk.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070801

Title: Desensitizing efficacy of a new toothpaste containing 5.5% potassium citrate: a 4-week clinical study.

Journal: American journal of dentistry 20070801

Title: Photoimages and the release characteristics of lipophilic matrix tablets containing highly water-soluble potassium citrate with high drug loadings.

Journal: International journal of pharmaceutics 20070718

Title: Effects of plant food potassium salts (citrate, galacturonate or tartrate) on acid-base status and digestive fermentations in rats.

Journal: The British journal of nutrition 20070701

Title: Comparison between lemonade and potassium citrate and impact on urine pH and 24-hour urine parameters in patients with kidney stone formation.

Journal: Urology 20070601

Title: Effect of medical management on recurrent stone formation following percutaneous nephrolithotomy.

Journal: The Journal of urology 20070501

Title: Kidney stones and the ketogenic diet: risk factors and prevention.

Journal: Journal of child neurology 20070401

Title: [Modulation of the phenotypic expression in the patient with cystinuria: influence of therapeutic intervention and diet].

Journal: Archivos espanoles de urologia 20070301

Title: Is bicarbonate solution tolerated better than Shohl's solution in neonatal renal tubular acidosis?

Journal: Pediatric nephrology (Berlin, Germany) 20070101

Title: Potassium may help fight osteoporosis. Potassium citrate increases bone-beneficial calcium retention.

Journal: DukeMedicine healthnews 20070101

Title: [Principles of concervative therapy of urolithiasis and prevention of stone formation recurrence].

Journal: Klinicheskaia meditsina 20070101

Title: Partial neutralization of the acidogenic Western diet with potassium citrate increases bone mass in postmenopausal women with osteopenia. Interview by Nicola Zitzmann.

Journal: The International journal of prosthodontics 20070101

Title: Acid-alkaline balance: role in chronic disease and detoxification.

Journal: Alternative therapies in health and medicine 20070101

Title: Partial neutralization of the acidogenic Western diet with potassium citrate increases bone mass in postmenopausal women with osteopenia.

Journal: Journal of the American Society of Nephrology : JASN 20061101

Title: Effect of potassium citrate therapy on stone recurrence and regrowth after extracorporeal shockwave lithotripsy in children.

Journal: Journal of endourology 20061101

Title: Organic potassium salts or fibers effects on mineral balance and digestive fermentations in rats adapted to an acidogenic diet.

Journal: European journal of nutrition 20060901

Title: Lemonade is an option for some hypocitraturic patients.

Journal: RN 20060701

Title: [Renal tubular acidosis].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20060510

Title: Xanthine urolithiasis.

Journal: Urology 20060501

Title: Subcutaneous fat necrosis with hypercalcemia.

Journal: Indian pediatrics 20060401

Title: Kidney stones: pathophysiology and medical management.

Journal: Lancet (London, England) 20060128

Title: Excess casein in the diet is not the unique cause of low-grade metabolic acidosis: role of a deficit in potassium citrate in a rat model.

Journal: Annals of nutrition & metabolism 20060101

Title: Hypocitraturia despite potassium citrate tablet supplementation.

Journal: MedGenMed : Medscape general medicine 20060101

Title: Scalable recovery of plasmid DNA based on aqueous two-phase separation.

Journal: Biotechnology and applied biochemistry 20050801

Title: Effect of short-term supplementation of potassium chloride and potassium citrate on blood pressure in hypertensives.

Journal: Hypertension (Dallas, Tex. : 1979) 20050401

Title: Citrate-preserved samples.

Journal: Journal of clinical forensic medicine 20050401

Title: Long-term potassium citrate therapy and bone mineral density in idiopathic calcium stone formers.

Journal: Journal of endocrinological investigation 20050301

Title: Renal tubular cell damage and oxidative stress in renal stone patients and the effect of potassium citrate treatment.

Journal: Urological research 20050201

Title: Effects of potassium-magnesium citrate supplementation on cytosolic ATP citrate lyase and mitochondrial aconitase activity in leukocytes: a window on renal citrate metabolism.

Journal: International journal of urology : official journal of the Japanese Urological Association 20050201

Title: Dietary potassium citrate does not harm the pcy mouse.

Journal: Experimental biology and medicine (Maywood, N.J.) 20050101

Title: A comparison of a reformulated potassium citrate desensitising toothpaste with the original proprietary product.

Journal: Journal of dentistry 20050101

Title: [Effects of potassium citrate delayed preparation in urine PH and citric acid content].

Journal: Zhonghua yi xue za zhi 20041102

Title: Stone forming risk of calcium citrate supplementation in healthy postmenopausal women.

Journal: The Journal of urology 20040901

Title: Limitation of apoptotic changes in renal tubular cell injury induced by hyperoxaluria.

Journal: Urological research 20040801

Title: Transient proximal renal tubular acidosis and Fanconi syndrome in a dog.

Journal: Journal of the American Veterinary Medical Association 20040515

Title: Effects of potassium citrate supplementation on bone metabolism.

Journal: Calcified tissue international 20040401

Title: Changes in urinary parameters after oral administration of potassium-sodium citrate and magnesium oxide to prevent urolithiasis.

Journal: Urology 20040101

Title: Sodium dicarboxylate cotransporter-1 expression in renal tissues and its role in rat experimental nephrolithiasis.

Journal: Journal of nephrology 20040101

Title: Comparative investigation of the desensitizing efficacy of a new dentifrice containing 5.5% potassium citrate: an eight-week clinical study.

Journal: The Journal of clinical dentistry 20040101

Title: Metabolic evaluation of 94 patients 5 to 16 years after ileocecal pouch (Mainz pouch 1) continent urinary diversion.

Journal: The Journal of urology 20031101

Title: Resolution of ephedrine stones with dissolution therapy.

Journal: Urology 20030501

Title: [Penetrometry in evaluation of flow and structure of powdered substances].

Journal: Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20030301

Title: Media calcification, low erythrocyte magnesium, altered plasma magnesium, and calcium homeostasis following grafting of the thoracic aorta to the infrarenal aorta in the rat--differential preventive effects of long-term oral magnesium supplementation alone and in combination with alkali.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20030301

Title: Prevention of stone formation and bone loss in absorptive hypercalciuria by combined dietary and pharmacological interventions.

Journal: The Journal of urology 20030201

Title: Long-term combined treatment with thiazide and potassium citrate in nephrolithiasis does not lead to hypokalemia or hypochloremic metabolic alkalosis.

Journal: Kidney international 20030101

Title: [A case of urolithiasis associated with short bowel syndrome].

Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20030101

Title: Bone histology and bone mineral density after correction of acidosis in distal renal tubular acidosis.

Journal: Kidney international 20021201

Title: Oral potassium citrate treatment for idiopathic hypocitruria in children with calcium urolithiasis.

Journal: The Journal of urology 20021201

Title: The optimal dose of potassium citrate in the treatment of children with distal renal tubular acidosis.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20021101

Title: Uric acid nephrolithiasis: current concepts and controversies.

Journal: The Journal of urology 20021001

Title: Intermittent versus continuous alkaline therapy for uric acid stones and ureteral stones of uncertain composition.

Journal: Urology 20020901

Title: Prevention of spinal bone loss by potassium citrate in cases of calcium urolithiasis.

Journal: The Journal of urology 20020701

Title: Potassium citrate prevents increased urine calcium excretion and bone resorption induced by a high sodium chloride diet.

Journal: The Journal of clinical endocrinology and metabolism 20020501

Title: Nephrolithiasis in a neonate with transient renal wasting of calcium and magnesium.

Journal: Pediatric nephrology (Berlin, Germany) 20020501

Title: Effect of potassium citrate therapy on stone recurrence and residual fragments after shockwave lithotripsy in lower caliceal calcium oxalate urolithiasis: a randomized controlled trial.

Journal: Journal of endourology 20020401

Title: Utility of oral dissolution therapy in the management of referred patients with secondarily treated uric acid stones.

Journal: Urology 20020201

Title: Dosage of potassium citrate in the correction of urinary abnormalities in pediatric distal renal tubular acidosis patients.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20020201

Title: [Effect of potassium citrate in the prophylaxis of urinary lithiasis].

Journal: Archivos espanoles de urologia 20011101

Title: A comparison of the effects of potassium citrate and sodium bicarbonate in the alkalinization of urine in homozygous cystinuria.

Journal: Urological research 20011001

Title: Distal renal tubular acidosis with severe hypokalaemia, probably caused by colonic H(+)-K(+)-ATPase deficiency.

Journal: Archives of disease in childhood 20010601

Title: Cystine calculi in children: the results of a metabolic evaluation and response to medical therapy.

Journal: The Journal of urology 20010601

Title: Oral preparations for flexible sigmoidoscopy.

Journal: Gastrointestinal endoscopy 20010501

Title: Chloride-sensitive renal microangiopathy in the stroke-prone spontaneously hypertensive rat.

Journal: Kidney international 20010301

Title: [Familial hypomagnesemia with hypercalciuria and nephrocalcinosis].

Journal: Anales espanoles de pediatria 20010201

Title: Potassium citrate administration ameliorates tubulointerstitial lesions in rats with uric acid nephropathy.

Journal: Clinical nephrology 20010101

Title: [Therapeutic use of potassium citrate].

Journal: Przeglad lekarski 20010101

Title: Effect of potassium magnesium citrate on thiazide-induced hypokalemia and magnesium loss.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 19990701

Title: Liu X, et al. Hydroxycitric acid inhibits renal calcium oxalate deposition by reducing oxidative stress and inflammation. Curr Mol Med. 2020 Jan 3.

Title: Ibuki M, et al. Therapeutic Effect of Garcinia cambogia Extract and Hydroxycitric Acid Inhibiting Hypoxia-Inducible Factor in a Murine Model of Age-Related Macular Degeneration. Int J Mol Sci. 2019 Oct 11;20(20). pii: E5049.

Title: Han S, et al. Hydroxycitric Acid Tripotassium Inhibits Calcium Oxalate Crystal Formation in the Drosophila Melanogaster Model of Hyperoxaluria. Med Sci Monit. 2019 May 17;25:3662-3667.

Title: Heymsfield SB, et al. Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial. JAMA. 1998 Nov 11;280(18):1596-600.

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Tags:6100-05-6 Molecular Formula|6100-05-6 MDL|6100-05-6 SMILES|6100-05-6 Potassium citrate monohydrate