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220620-09-7,MFCD00935753
Catalog No.:AA003UQG

220620-09-7 | Tigecycline

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Purity
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25mg
98%(HPLC)
in stock  
$48.00   $34.00
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100mg
≥ 98.5% (HPLC)
in stock  
$72.00   $50.00
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250mg
≥ 98.5% (HPLC)
in stock  
$122.00   $85.00
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1g
≥ 98.5% (HPLC)
in stock  
$322.00   $225.00
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5g
≥ 98.5% (HPLC)
in stock  
$1,386.00   $970.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003UQG
Chemical Name:
Tigecycline
CAS Number:
220620-09-7
Molecular Formula:
C29H39N5O8
Molecular Weight:
585.6487
MDL Number:
MFCD00935753
SMILES:
O=C(Nc1cc(N(C)C)c2c(c1O)C(=O)C1=C(O)[C@]3([C@@H](C[C@@H]1C2)[C@H](N(C)C)C(=C(C3=O)C(=O)N)O)O)CNC(C)(C)C
Properties
Properties
 
Form:
Solid  
MP:
164-166°C  
Storage:
Light sensitive;Inert atmosphere;-20 ℃;  

Computed Properties
 
Complexity:
1240  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
42  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
7  
Rotatable Bond Count:
7  
XLogP3:
1.1  

Literature

Title: Activities of Omadacycline and Comparator Agents against Staphylococcus aureus Isolates from a Surveillance Program Conducted in North America and Europe.

Journal: Antimicrobial agents and chemotherapy 20170301

Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.

Journal: Chemical research in toxicology 20150518

Title: Tigecycline prevents LPS-induced release of pro-inflammatory and apoptotic mediators in neuronal cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20130301

Title: In vitro susceptibility of multidrug-resistant Enterobacteriaceae clinical isolates to tigecycline.

Journal: The Journal of antimicrobial chemotherapy 20121101

Title: Bacteremia caused by Acinetobacter junii at a medical center in Taiwan, 2000-2010.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20121001

Title: Enhancement of antistaphylococcal activities of six antimicrobials against sasG-negative methicillin-susceptible Staphylococcus aureus: an in vitro biofilm model.

Journal: Diagnostic microbiology and infectious disease 20121001

Title: In vitro activity of tigecycline and comparators against organisms associated with intra-abdominal infections collected as part of TEST (2004-2009).

Journal: Diagnostic microbiology and infectious disease 20121001

Title: Efficacy of tigecycline/colistin combination in a pneumonia model caused by extensively drug-resistant Acinetobacter baumannii.

Journal: International journal of antimicrobial agents 20121001

Title: Tigecycline pharmacokinetics in subjects with various degrees of renal function.

Journal: Journal of clinical pharmacology 20120901

Title: Pharmacokinetic-pharmacodynamic evaluation of daptomycin, tigecycline, and linezolid versus vancomycin for the treatment of MRSA infections in four western European countries.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20120901

Title: Growing prevalence of Providencia stuartii associated with the increased usage of colistin at a tertiary health care center.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20120901

Title: Clinical outcomes of tigecycline in the treatment of multidrug-resistant Acinetobacter baumannii infection.

Journal: Yonsei medical journal 20120901

Title: [Evaluation of the variability in the susceptibility of Acinetobacter baumannii to tigecycline in the same medium with two methods of quantitative diffusion different commercial].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20120901

Title: FDA limits acetaminophen; risk of death with tigecycline.

Journal: JAAPA : official journal of the American Academy of Physician Assistants 20120901

Title: In vitro activity and in vivo efficacy of tigecycline alone and in combination with daptomycin and rifampin against Gram-positive cocci isolated from surgical wound infection.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20120801

Title: In vitro antimicrobial activity of 'last-resort' antibiotics against unusual nonfermenting Gram-negative bacilli clinical isolates.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20120801

Title: Imbalanced mortality evidence for tigecycline: 2011, the year of the meta-analysis.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120801

Title: Efficacy of tigecycline and rifampin alone and in combination against Enterococcus faecalis biofilm infection in a rat model of ureteral stent.

Journal: The Journal of surgical research 20120701

Title: Tigecycline-resistant Enterococcus faecalis associated with omeprazole use in a surgical patient.

Journal: The Journal of antimicrobial chemotherapy 20120701

Title: Antimicrobial susceptibility patterns of multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii against carbapenems, colistin, and tigecycline.

Journal: Saudi medical journal 20120701

Title: [Evaluation of antibiotic susceptibilities and VISA-VRSA rates among MRSA strains isolated from hospitalized patients in intensive care units of hospitals in seven provinces of Turkey].

Journal: Mikrobiyoloji bulteni 20120701

Title: Excess deaths associated with tigecycline after approval based on noninferiority trials.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120615

Title: Editorial commentary: Asking the right questions: morbidity, mortality, and measuring what's important in unbiased evaluations of antimicrobials.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120615

Title: Successful tigecycline lock therapy in a Lactobacillus rhamnosus catheter-related bloodstream infection.

Journal: Infection 20120601

Title: Susceptibility of global intra-abdominal Enterobacteriaceae isolates to tigecycline (TEST 2007-2010).

Journal: The Journal of infection 20120601

Title: Effectiveness and safety of tigecycline: focus on use for approved indications.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120601

Title: Trending 7 years of in vitro activity of tigecycline and comparators against Gram-positive and Gram-negative pathogens from the Asia-Pacific region: Tigecycline Evaluation Surveillance Trial (TEST) 2004-2010.

Journal: International journal of antimicrobial agents 20120601

Title: Tigecycline as a therapeutic option in Stenotrophomonas maltophilia infections.

Journal: Journal of chemotherapy (Florence, Italy) 20120601

Title: Tigecycline and intravenous fosfomycin zone breakpoints equivalent to the EUCAST MIC criteria for Enterobacteriaceae.

Journal: Journal of infection in developing countries 20120514

Title: In vitro activity of tigecycline against multidrug-resistant Gram-negative blood culture isolates from critically ill patients.

Journal: The Journal of antimicrobial chemotherapy 20120501

Title: Acute necrotizing pancreatitis related to tigecycline.

Journal: The Journal of antimicrobial chemotherapy 20120501

Title: In vitro interference of tigecycline at subinhibitory concentrations on biofilm development by Enterococcus faecalis.

Journal: The Journal of antimicrobial chemotherapy 20120501

Title: More about the safety of tigecycline for the treatment of infectious diseases: the role of superinfection rates.

Journal: The Journal of antimicrobial chemotherapy 20120401

Title: Lack of effect of extracorporeal membrane oxygenation on tigecycline pharmacokinetics.

Journal: The Journal of antimicrobial chemotherapy 20120401

Title: Efficacy of tigecycline and vancomycin in experimental catheter-related Staphylococcus epidermidis infection: microbiological and electron microscopic analysis of biofilm.

Journal: International journal of antimicrobial agents 20120401

Title: Efficacy of tigecycline versus ceftriaxone plus metronidazole for the treatment of complicated intra-abdominal infections: results from a randomized, controlled trial.

Journal: Surgical infections 20120401

Title: Therapeutic potential of mitochondrial translation inhibition for treatment of acute myeloid leukemia.

Journal: Expert review of hematology 20120401

Title: Antimicrobial susceptibility among E. faecalis and E. faecium from France, Germany, Italy, Spain and the UK (T.E.S.T. Surveillance Study, 2004-2009).

Journal: Journal of chemotherapy (Florence, Italy) 20120401

Title: In vitro activity of tigecycline against Acinetobacter baumannii isolates from a teaching hospital in Malaysia.

Journal: Journal of chemotherapy (Florence, Italy) 20120401

Title: Intravitreal tigecycline treatment in experimental Acinetobacter baumannii endophthalmitis.

Journal: Journal of chemotherapy (Florence, Italy) 20120401

Title: In vitro time-kill studies of antimicrobial agents against blood isolates of imipenem-resistant Acinetobacter baumannii, including colistin- or tigecycline-resistant isolates.

Journal: Journal of medical microbiology 20120301

Title: Recurrent refractory Clostridium difficile colitis treated successfully with rifaximin and tigecycline: a case report and review of the literature.

Journal: Scandinavian journal of infectious diseases 20120301

Title: Efficacies of colistin and tigecycline in mice with experimental pneumonia due to NDM-1-producing strains of Klebsiella pneumoniae and Escherichia coli.

Journal: International journal of antimicrobial agents 20120301

Title: [Stenotrophomonas maltophilia and tigecycline in clinical practice].

Journal: Enfermedades infecciosas y microbiologia clinica 20120301

Title: Guideline summary: appropriate use of tigecycline.

Journal: South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie 20120214

Title: Clonal spread of multidrug-resistant Acinetobacter baumannii in eastern Taiwan.

Journal: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20120201

Title: In vitro activity of tigecycline and comparators against Gram-negative pathogens isolated from blood in Europe (2004-2009).

Journal: International journal of antimicrobial agents 20120201

Title: Pharmacokinetics and safety profile of tigecycline in children aged 8 to 11 years with selected serious infections: a multicenter, open-label, ascending-dose study.

Journal: Clinical therapeutics 20120201

Title: Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent.

Journal: Journal of medicinal chemistry 20120126

Title: Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy.

Journal: Journal of medicinal chemistry 20120126

Title: Klebsiella pneumoniae: development of a mixed population of carbapenem and tigecycline resistance during antimicrobial therapy in a kidney transplant patient.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20120101

Title: Management of gram-positive bacterial infections in patients with cancer.

Journal: Leukemia & lymphoma 20120101

Title: Tigecycline option for the treatment of bone and joint infections caused by multidrug-resistant Staphylococcus epidermidis.

Journal: Joint, bone, spine : revue du rhumatisme 20120101

Title: Calcium-dependent potentiation of the pro-inflammatory functions of human neutrophils by tigecycline in vitro.

Journal: The Journal of antimicrobial chemotherapy 20120101

Title: Tigecycline accelerates staphylococcal-infected burn wound healing through matrix metalloproteinase-9 modulation.

Journal: The Journal of antimicrobial chemotherapy 20120101

Title: Activity of tigecycline and comparators against skin and skin structure pathogens: global results of the Tigecycline evaluation and surveillance trial, 2004-2009.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20120101

Title: Antimicrobial susceptibility among gram-negative isolates collected from intensive care units in North America, Europe, the Asia-Pacific Rim, Latin America, the Middle East, and Africa between 2004 and 2009 as part of the Tigecycline Evaluation and Surveillance Trial.

Journal: Clinical therapeutics 20120101

Title: Changes in MIC within a global collection of Acinetobacter baumannii collected as part of the Tigecycline Evaluation and Surveillance Trial, 2004 to 2009.

Journal: Clinical therapeutics 20120101

Title: Successful treatment of multidrug-resistant Escherichia coli bacteremia with tigecycline in an acute myeloid leukemia child.

Journal: The Turkish journal of pediatrics 20120101

Title: Successful salvage therapy with Daptomycin for osteomyelitis caused by methicillin-resistant Staphylococcus aureus in a renal transplant recipient with Fabry-Anderson disease.

Journal: Annals of clinical microbiology and antimicrobials 20120101

Title: In vitro activity of tigecycline against clinical isolates of carbapenem resistant Acinetobacter baumannii complex in Pretoria, South Africa.

Journal: BMC research notes 20120101

Title: Drugs of last resort? The use of polymyxins and tigecycline at US Veterans Affairs medical centers, 2005-2010.

Journal: PloS one 20120101

Title: Adverse event profile of tigecycline: data mining of the public version of the U.S. Food and Drug Administration adverse event reporting system.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Extended-spectrum β-lactamase-producing Enterobacteriaceae: in vitro susceptibility to fosfomycin, nitrofurantoin and tigecycline.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20120101

Title: [Susceptibility rate to tigecycline and antibiotic-resistance among Klebsiella pneumoniae strains isolated in Intensive Care Unit].

Journal: Recenti progressi in medicina 20120101

Title: In vitro activity of tigecycline and molecular characterization of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates from a university hospital in south-western Germany.

Journal: Chemotherapy 20120101

Title: Tigecycline-induced acute pancreatitis: about two cases and review of the literature.

Journal: Acta clinica Belgica 20120101

Title: Leuconostoc garlicum: an unusual pathogen in the era of vancomycin therapy.

Journal: The Indian journal of chest diseases & allied sciences 20120101

Title: [Perspectives of tigecycline treatment of surgical site infections in oncologic patients].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20120101

Title: Antibiotic activity of tigecycline against clinical pathogens by the micro dilution method.

Journal: Anaerobe 20111201

Title: Outcomes in patients infected with carbapenem-resistant Acinetobacter baumannii and treated with tigecycline alone or in combination therapy.

Journal: Infection 20111201

Title: Vitamin E improves the in vivo efficacy of tigecycline and daptomycin in an animal model of wounds infected with meticillin-resistant Staphylococcus aureus.

Journal: Journal of medical microbiology 20111201

Title: Genotypic characterization and in vitro activities of tigecycline and polymyxin B for members of the Enterobacteriaceae with decreased susceptibility to carbapenems.

Journal: Journal of medical microbiology 20111201

Title: In vitro activity of tigecycline and comparators against gram-negative bacteria isolated from a tertiary hospital in Alexandria, Egypt.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20111201

Title: Investigation of the prevalence of tetQ, tetX and tetX1 genes in Bacteroides strains with elevated tigecycline minimum inhibitory concentrations.

Journal: International journal of antimicrobial agents 20111201

Title: Efficacy of minocycline and tigecycline in a hamster model of leptospirosis.

Journal: Diagnostic microbiology and infectious disease 20111201

Title: Susceptibility to tigecycline and linezolid among gram-positive isolates collected in the United States as part of the tigecycline evaluation and surveillance trial (TEST) between 2004 and 2009.

Journal: Clinical therapeutics 20111201

Title: Tigecycline penetration into skin and soft tissue.

Journal: Surgical infections 20111201

Title: [Antimicrobial sensitivity of hippurate-negative Campylobacter and Helicobacter pullorum strains isolated from patients with diarrhea].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Is tigecyclin a good choice in the treatment of multidrug-resistant Acinetobacter baumannii pneumonia?

Journal: Journal of chemotherapy (Florence, Italy) 20111201

Title: Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.

Journal: Cancer cell 20111115

Title: Tigecycline: benefits and risks.

Journal: The Lancet. Infectious diseases 20111101

Title: Efficacy and safety of tigecycline for the treatment of infectious diseases: a meta-analysis.

Journal: The Lancet. Infectious diseases 20111101

Title: Telavancin for the treatment of methicillin-resistant Staphylococcus aureus osteomyelitis.

Journal: The Journal of antimicrobial chemotherapy 20111101

Title: The clinical implication and prognostic predictors of tigecycline treatment for pneumonia involving multidrug-resistant Acinetobacter baumannii.

Journal: The Journal of infection 20111101

Title: Breakthrough bacteraemia due to tigecycline-resistant Escherichia coli with New Delhi metallo-β-lactamase (NDM)-1 successfully treated with colistin in a patient with calciphylaxis.

Journal: The Journal of antimicrobial chemotherapy 20111101

Title: Pharmacokinetic and pharmacodynamic evaluation of tigecycline.

Journal: Expert opinion on drug metabolism & toxicology 20111101

Title: A multidrug-resistant Acinetobacter baumannii outbreak in intensive care unit: antimicrobial and organizational strategies.

Journal: Journal of critical care 20111001

Title: Microbial isolation and emergence of antimicrobial resistance associated with tigecycline usage.

Journal: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20111001

Title: In vitro activity of linezolid, tigecycline, and daptomycin on methicillin-resistant Staphylococcus aureus blood isolates from adult patients, 2006-2008: stratified analysis by vancomycin MIC.

Journal: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20111001

Title: In vitro evaluation of antibiotic synergy for NDM-1-producing Enterobacteriaceae.

Journal: The Journal of antimicrobial chemotherapy 20111001

Title: [Evaluation of vancomycin, teicoplanin, linezolide and tigecycline susceptibilities of nosocomial methicillin-resistant Staphylococcus strains by E-test].

Journal: Mikrobiyoloji bulteni 20111001

Title: Resistance trends and in vitro activity of tigecycline and 17 other antimicrobial agents against Gram-positive and Gram-negative organisms, including multidrug-resistant pathogens, in Germany.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20110901

Title: Comparative activity of tigecycline and tetracycline on Gram-negative and Gram-positive bacteria revealed by a multicentre study in four North European countries.

Journal: Scandinavian journal of infectious diseases 20110901

Title: Efficacy and safety of tigecycline: a systematic review and meta-analysis.

Journal: The Journal of antimicrobial chemotherapy 20110901

Title: Efficacy of tigecycline alone and with rifampin in foreign-body infection by methicillin-resistant Staphylococcus aureus.

Journal: The Journal of infection 20110901

Title: Outcomes and genetic relatedness of carbapenem-resistant enterobacteriaceae at Detroit medical center.

Journal: Infection control and hospital epidemiology 20110901

Title: Tigecycline attenuates polymorphonuclear leukocyte (PMN) receptors but not functions.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20110901

Title: Efficacy of tigecycline pleurodesis: a comparative experimental study.

Journal: The Journal of surgical research 20110801

Title: Anti-anaerobic activity of serum from patients treated with tigecycline for skin/soft tissue infections.

Journal: Anaerobe 20110801

Title: [Mycobacterium abscessus pulmonary infection treated with tigecyclin-amikacin and cefoxitin in a diabetic patient].

Journal: Medecine et maladies infectieuses 20110801

Title: Non-susceptibility to tigecycline in enterococci from hospitalised patients, food products and community sources.

Journal: International journal of antimicrobial agents 20110801

Title: Metallo-β-lactamase-producing Enterobacteriaceae isolates at a Taiwanese hospital: lack of distinctive phenotypes for screening.

Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20110801

Title: Vancomycin-resistant Enterococcus faecium (VRE) bacteremia in infective endocarditis successfully treated with combination daptomycin and tigecycline.

Journal: Journal of chemotherapy (Florence, Italy) 20110801

Title: Genetic regulation of the ramA locus and its expression in clinical isolates of Klebsiella pneumoniae.

Journal: International journal of antimicrobial agents 20110701

Title: In vitro efficacy of antimicrobial agents against high-inoculum or biofilm-embedded meticillin-resistant Staphylococcus aureus with vancomycin minimal inhibitory concentrations equal to 2 μg/mL (VA2-MRSA).

Journal: International journal of antimicrobial agents 20110701

Title: Whole-genome comparison of two Acinetobacter baumannii isolates from a single patient, where resistance developed during tigecycline therapy.

Journal: The Journal of antimicrobial chemotherapy 20110701

Title: Tigecycline for the treatment of severe Clostridium difficile infection.

Journal: The Annals of pharmacotherapy 20110701

Title: [Staphylococcus aureus and antibiotic resistance].

Journal: Mikrobiyoloji bulteni 20110701

Title: Skin and soft tissue infections due to methicillin-resistant Staphylococcus aureus: role of tigecycline.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20110615

Title: Synthesis and antibacterial activity of pentacyclines: a novel class of tetracycline analogs.

Journal: Journal of medicinal chemistry 20110609

Title: Comparative in vitro susceptibility of Burkholderia pseudomallei to doripenem, ertapenem, tigecycline and moxifloxacin.

Journal: International journal of antimicrobial agents 20110601

Title: Global in vitro activity of tigecycline and linezolid against Gram-positive organisms collected between 2004 and 2009.

Journal: International journal of antimicrobial agents 20110601

Title: In vitro activity of tigecycline against extended-spectrum β-lactamase-producing Enterobacteriaceae and MRSA clinical isolates from Mexico: a multicentric study.

Journal: Diagnostic microbiology and infectious disease 20110601

Title: Emergence of tigecycline & colistin resistant Acinetobacter baumanii in patients with complicated urinary tract infections in north India.

Journal: The Indian journal of medical research 20110601

Title: Tigecycline treatment for urinary tract infections: case report and literature review.

Journal: Journal of chemotherapy (Florence, Italy) 20110601

Title: Multidrug-resistant Gram-negative bacilli causing urinary tract infections: clinical considerations.

Journal: Journal of chemotherapy (Florence, Italy) 20110601

Title: Comment on: Newer antibacterial agents and their potential role in cystic fibrosis pulmonary exacerbation management.

Journal: The Journal of antimicrobial chemotherapy 20110501

Title: Malignant syphilis with ocular involvement in an HIV-infected patient.

Journal: International journal of STD & AIDS 20110501

Title: Intravenous tigecycline in the treatment of severe recurrent Clostridium difficile colitis.

Journal: The Medical journal of Australia 20110404

Title: Pan-resistant Acinetobacter baumannii mediastinitis treated successfully with tigecycline: a case report.

Journal: Surgical infections 20110401

Title: Extreme alkaline phosphatase elevation associated with tigecycline.

Journal: The Journal of antimicrobial chemotherapy 20110401

Title: Comparison of ceftaroline fosamil, daptomycin and tigecycline in an experimental rabbit endocarditis model caused by methicillin-susceptible, methicillin-resistant and glycopeptide-intermediate Staphylococcus aureus.

Journal: The Journal of antimicrobial chemotherapy 20110401

Title: Treatment and outcomes in carbapenem-resistant Klebsiella pneumoniae bloodstream infections.

Journal: Diagnostic microbiology and infectious disease 20110401

Title: Tigecycline for treating ventilator-associated pneumonia: a practical perspective.

Journal: Diagnostic microbiology and infectious disease 20110401

Title: Efficacy and safety of tigecycline monotherapy compared with vancomycin-aztreonam in the treatment of complicated skin and skin structure infections in patients from India and Taiwan.

Journal: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20110401

Title: Successful treatment of nodular lymphangitis due to Mycobacterium chelonae in two immunosuppressed patients.

Journal: Dermatology online journal 20110315

Title: 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents.

Journal: Journal of medicinal chemistry 20110310

Title: Activity of tigecycline alone and in combination with colistin and meropenem against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae strains by time-kill assay.

Journal: International journal of antimicrobial agents 20110301

Title: In vitro susceptibilities of clinical isolates of ertapenem-non-susceptible Enterobacteriaceae to nemonoxacin, tigecycline, fosfomycin and other antimicrobial agents.

Journal: International journal of antimicrobial agents 20110301

Title: Susceptibility patterns of coagulase-negative staphylococci to several newer antimicrobial agents in comparison with vancomycin and oxacillin.

Journal: International journal of antimicrobial agents 20110301

Title: Management of serious meticillin-resistant Staphylococcus aureus infections: what are the limits?

Journal: International journal of antimicrobial agents 20110301

Title: Comparison of community-associated and health care-associated methicillin-resistant Staphylococcus aureus in Canada: results of the CANWARD 2007-2009 study.

Journal: Diagnostic microbiology and infectious disease 20110301

Title: An unexpected similarity between antibiotic-resistant NDM-1 and beta-lactamase II from Erythrobacter litoralis.

Journal: Protein & cell 20110301

Title: Tigecycline for severe infections: the gap between the warning and the necessity.

Journal: The Journal of antimicrobial chemotherapy 20110201

Title: Tigecycline treatment of critically ill patients: the LatinUser experience.

Journal: Current clinical pharmacology 20110201

Title: Altered bioavailability of tacrolimus following intravenous administration of tigecycline.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20110201

Title: Tigecycline activity tested against multidrug-resistant Enterobacteriaceae and Acinetobacter spp. isolated in US medical centers (2005-2009).

Journal: Diagnostic microbiology and infectious disease 20110201

Title: Off-label use of antibiotics in intensive care unit: the multidrug-resistant pathogens challenge.

Journal: Journal of critical care 20110201

Title: Emergence of tigecycline and colistin resistance in Acinetobacter species isolated from patients in Kuwait hospitals.

Journal: Journal of chemotherapy (Florence, Italy) 20110201

Title: Pharmacokinetics and safety of a single intravenous dose of the antibiotic tigecycline in patients with cirrhosis.

Journal: Journal of clinical pharmacology 20110101

Title: Roles of Salmonella multidrug efflux pumps in tigecycline resistance.

Journal: The Journal of antimicrobial chemotherapy 20110101

Title: [Experience with tigecycline in the treatment of multiresistant germs in the ICU].

Journal: Medicina intensiva 20110101

Title: Activities of tigecycline and comparators against Legionella pneumophila and Legionella micdadei extracellularly and in human monocyte-derived macrophages.

Journal: Diagnostic microbiology and infectious disease 20110101

Title: A rare human infection of Raoultella ornithinolytica in a diabetic foot lesion.

Journal: Annals of Saudi medicine 20110101

Title: Treatment of methicillin-resistant Staphylococcus aureus surgical site infections.

Journal: AACN advanced critical care 20110101

Title: First case of resistance to tigecycline by Klebsiella pneumoniae in a European University Hospital.

Journal: Indian journal of medical microbiology 20110101

Title: Time-kill synergy tests of tigecycline combined with imipenem, amikacin, and ciprofloxacin against clinical isolates of multidrug-resistant Klebsiella pneumoniae and Escherichia coli.

Journal: Annals of clinical and laboratory science 20110101

Title: Multidrug-resistant gram-negative infections. Bringing back the old.

Journal: Critical care nursing quarterly 20110101

Title: Antimicrobial susceptibilities of Brucella isolates from various clinical specimens.

Journal: International journal of medical sciences 20110101

Title: In-vitro activity of polymyxin B, rifampicin, tigecycline alone and in combination against carbapenem-resistant Acinetobacter baumannii in Singapore.

Journal: PloS one 20110101

Title: Prospective, non-interventional, multi-centre trial of tigecycline in the treatment of severely ill patients with complicated infections: new insights into clinical results and treatment practice.

Journal: Chemotherapy 20110101

Title: Robust and sensitive high-performance liquid chromatographic-UV detection technique for the determination of tigecycline in rabbit plasma.

Journal: Journal of AOAC International 20110101

Title: [A case of legionellesis pneumonia verified by isolation of Legionella pneumophila serogroup 1 from bronchoalveolar lavage fluid treated with levofloxacine and tigecycline].

Journal: Terapevticheskii arkhiv 20110101

Title: Resistance patterns and occurrence of virulence determinants among GRE strains in southwestern Poland.

Journal: Advances in medical sciences 20110101

Title: Two cases of monomicrobial intraabdominal abscesses due to KPC--3 Klebsiella pneumoniae ST258 clone.

Journal: BMC gastroenterology 20110101

Title: [Susceptibility of Klebsiella oxytoca to selected antibiotics].

Journal: Medycyna doswiadczalna i mikrobiologia 20110101

Title: Fusobacterium necrophorum--beyond Lemierres syndrome.

Journal: BMJ case reports 20110101

Title: Multidrug-resistant Acinetobacter baumannii infection in children.

Journal: BMJ case reports 20110101

Title: [Present stage of chemotherapy and chemoprophylaxis of rickettsiosis and Q fever].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101

Title: Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model.

Journal: Antimicrobial agents and chemotherapy 20101201

Title: Tigecycline activity: low resistance rates but problematic disc breakpoints revealed by a multicentre sentinel survey in the UK.

Journal: The Journal of antimicrobial chemotherapy 20101201

Title: Multidrug-resistant Gram-negative bacteria: how to treat and for how long.

Journal: International journal of antimicrobial agents 20101201

Title: [Role of daptomycin in the treatment of infections in patients with hematological malignancies].

Journal: Medicina clinica 20101201

Title: In vitro activity of nemonoxacin, tigecycline, and other antimicrobial agents against Helicobacter pylori isolates in Taiwan, 1998-2007.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20101101

Title: Susceptibility of Candida albicans biofilms to azithromycin, tigecycline and vancomycin and the interaction between tigecycline and antifungals.

Journal: International journal of antimicrobial agents 20101101

Title: Successful treatment of pan-resistant Klebsiella pneumoniae pneumonia and bacteraemia with a combination of high-dose tigecycline and colistin.

Journal: Journal of medical microbiology 20101101

Title: Prevalence of antimicrobial-resistant pathogens in Canadian hospitals: results of the Canadian Ward Surveillance Study (CANWARD 2008).

Journal: Antimicrobial agents and chemotherapy 20101101

Title: Off-label prescription of tigecycline: clinical and microbiological characteristics and outcomes.

Journal: International journal of antimicrobial agents 20101101

Title: Salvage therapy with tigecycline for recurrent infection caused by ertapenem-resistant extended-spectrum β-lactamase-producing Klebsiella pneumoniae.

Journal: Diagnostic microbiology and infectious disease 20101101

Title: Empirical first-line treatment with tigecycline for febrile episodes following abdominal surgery in cancer patients.

Journal: International journal of antimicrobial agents 20101101

Title: Mechanical integrity of hemodialysis catheters after exposure to a novel catheter lock solution.

Journal: Infection control and hospital epidemiology 20101101

Title: Comprehensive assessment of tigecycline activity tested against a worldwide collection of Acinetobacter spp. (2005-2009).

Journal: Diagnostic microbiology and infectious disease 20101101

Title: Severe coagulation disorder with hypofibrinogenemia associated with the use of tigecycline.

Journal: Annals of hematology 20101001

Title: Brucellosis in a patient with end-stage liver disease undergoing liver transplantation: successful treatment with tigecycline.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20101001

Title: Mortality associated with Acinetobacter baumannii infections experienced by lung transplant recipients.

Journal: Lung 20101001

Title: Emergence of tigecycline resistance amongst multi-drug resistant gram negative isolates in a multi-disciplinary hospital.

Journal: The Journal of infection 20101001

Title: Zone breakpoints, by the CLSI disc method, for 15 μg tigecycline discs corresponding to EUCAST MIC breakpoints.

Journal: The Journal of antimicrobial chemotherapy 20101001

Title: Tigecycline and bacteremia--the dangers of post hoc analysis of pooled data.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20101001

Title: Comparison of tigecycline with imipenem/cilastatin for the treatment of hospital-acquired pneumonia.

Journal: Diagnostic microbiology and infectious disease 20101001

Title: Methicillin-resistant Staphylococcus aureus: the superbug.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20101001

Title: Economic impact simulation analysis of use of tigecycline, as appropriate, in first-course antibiotic therapy for complicated intra-abdominal infections in intensive care patients.

Journal: Minerva medica 20101001

Title: [In vitro tigecycline and carbapenem susceptibilities of clinical Acinetobacter baumannii isolates].

Journal: Mikrobiyoloji bulteni 20101001

Title: Factors associated with adherence to guidelines for the use of tigecycline in a tertiary care hospital.

Journal: Journal of chemotherapy (Florence, Italy) 20101001

Title: Tigecycline use in two cases with multidrug-resistant Acinetobacter baumannii meningitis.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20100901

Title: The susceptibility to tigecycline of Acinetobacter spp. may vary depending on the methodology used.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20100901

Title: Successful treatment with tigecycline of two patients with complicated urinary tract infections caused by extended-spectrum beta-lactamase-producing Escherichia coli.

Journal: The Journal of antimicrobial chemotherapy 20100901

Title: In vitro activity of tigecycline against carbapenemase-producing Acinetobacter baumannii.

Journal: International journal of antimicrobial agents 20100901

Title: Newer antibacterial agents and their potential role in cystic fibrosis pulmonary exacerbation management.

Journal: The Journal of antimicrobial chemotherapy 20100901

Title: Pediatric acute pancreatitis related to tigecycline.

Journal: The Pediatric infectious disease journal 20100901

Title: In vitro activity of tigecycline in combination with gentamicin against biofilm-forming Staphylococcus aureus.

Journal: Diagnostic microbiology and infectious disease 20100901

Title: In vitro activity of tigecycline and comparators on Acinetobacter spp. isolates collected from patients with bacteremia and MIC change during the Tigecycline Evaluation and Surveillance Trial, 2004 to 2008.

Journal: Diagnostic microbiology and infectious disease 20100901

Title: Influence of different Mueller-Hinton agars and media age on Etest susceptibility testing of tigecycline.

Journal: Diagnostic microbiology and infectious disease 20100901

Title: Resistant pathogen-associated skin and skin-structure infections: antibiotic options.

Journal: Expert review of anti-infective therapy 20100901

Title: Pharmacogenomic strategies against microbial resistance: from bright to bleak to innovative.

Journal: Pharmacogenomics 20100901

Title: [Tigecycline--a new antibiotic].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20100826

Title: Efflux pumps may play a role in tigecycline resistance in Burkholderia species.

Journal: International journal of antimicrobial agents 20100801

Title: Exposure-response analysis of tigecycline in pharmacodynamic simulations using different size inocula of target bacteria.

Journal: International journal of antimicrobial agents 20100801

Title: Activity of tigecycline and comparators against recent clinical isolates of Finegoldia magna from Europe.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20100801

Title: Tigecycline inhibition of a mature biofilm in clinical isolates of Staphylococcus aureus : comparison with other drugs.

Journal: FEMS immunology and medical microbiology 20100801

Title: In vitro activities of tigecycline alone and in combination with colistin sulfate or sulbactam against carbapenem-susceptible and -resistant Acinetobacter baumannii strains isolated from Intensive Care Units.

Journal: International journal of antimicrobial agents 20100801

Title: AdeABC-mediated efflux and tigecycline MICs for epidemic clones of Acinetobacter baumannii.

Journal: The Journal of antimicrobial chemotherapy 20100801

Title: Tigecycline treatment of multi-drug-resistant Corynebacterium jeikeium infection in a child with relapsing and refractory acute lymphoblastic leukemia.

Journal: Pediatric blood & cancer 20100801

Title: A multicentre, open-label, randomized comparative study of tigecycline versus ceftriaxone sodium plus metronidazole for the treatment of hospitalized subjects with complicated intra-abdominal infections.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20100801

Title: [Assessment of tigecycline use economic impact in first-line therapy for complicated intra-abdominal infections in an Intensive Care Unit].

Journal: Minerva medica 20100801

Title: Susceptibility of Burkholderia pseudomallei to tigecycline and other antimicrobials.

Journal: Diagnostic microbiology and infectious disease 20100701

Title: S-thanatin enhances the efficacy of tigecycline in an experimental rat model of polymicrobial peritonitis.

Journal: Peptides 20100701

Title: Superinfection during treatment of nosocomial infections with tigecycline.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20100701

Title: Therapeutic options for bacteremia caused by extended-spectrum beta-lactamase-producing Escherichia coli.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100701

Title: Failure of tigecycline to treat severe Clostridium difficile infection.

Journal: Anaesthesia and intensive care 20100701

Title: Hospital policies and practices on prevention and treatment of infections caused by methicillin-resistant Staphylococcus aureus.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100615

Title: Primary retroperitoneal abscesses due to Rhodococcus equi in a patient with severe nephrotic syndrome: successful antibiotic treatment with linezolid and tigecycline.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20100601

Title: In vitro activity of tigecycline in Plasmodium falciparum culture-adapted strains and clinical isolates from Gabon.

Journal: International journal of antimicrobial agents 20100601

Title: The in vitro evaluation of tigecycline tested against pathogens isolated in eight countries in the Asia-Western Pacific region (2008).

Journal: The Journal of infection 20100601

Title: Detection and treatment options for Klebsiella pneumoniae carbapenemases (KPCs): an emerging cause of multidrug-resistant infection.

Journal: The Journal of antimicrobial chemotherapy 20100601

Title: Should tigecycline be considered for urinary tract infections? A pharmacokinetic re-evaluation.

Journal: The Journal of antimicrobial chemotherapy 20100601

Title: Tigecycline: a review of properties, applications, and analytical methods.

Journal: Therapeutic drug monitoring 20100601

Title: RT-PCR and statistical analyses of adeABC expression in clinical isolates of Acinetobacter calcoaceticus-Acinetobacter baumannii complex.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20100601

Title: Susceptibility of Klebsiella spp. to tigecycline and other selected antibiotics.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20100601

Title: Guideline: appropriate use of tigecycline.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20100601

Title: [Differences in the use of tigecycline between ICU patients and non-ICU patients].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20100601

Title: [Variability in the sensitivity to tigecycline against Acinetobacter baumannii in different culture media].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20100601

Title: A combination of tigecycline, colistin, and meropenem against multidrug-resistant Acinetobacter baumannii bacteremia in a renal transplant recipient: pharmacodynamic and microbiological aspects.

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20100601

Title: Efficacy of tigecycline vs. imipenem in the treatment of experimental Acinetobacter baumannii murine pneumonia.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20100501

Title: In vitro activity of tigecycline against methicillin-resistant Staphylococcus aureus, including livestock-associated strains.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20100501

Title: Emergence of AcrAB-mediated tigecycline resistance in a clinical isolate of Enterobacter cloacae during ciprofloxacin treatment.

Journal: International journal of antimicrobial agents 20100501

Title: Global monitoring of cross-resistance between tigecycline and minocycline, 2004-2009.

Journal: The Journal of infection 20100501

Title: [Tigecycline for treatment of severe infections in intensive care: a drug use evaluation].

Journal: Annales francaises d'anesthesie et de reanimation 20100501

Title: Antimicrobial activity against Streptococcus pneumoniae and Haemophilus influenzae collected globally between 2004 and 2008 as part of the Tigecycline Evaluation and Surveillance Trial.

Journal: Diagnostic microbiology and infectious disease 20100501

Title: Multidrug-resistant Enterococcus faecium meningitis in a toddler: characterization of the organism and successful treatment with intraventricular daptomycin and intravenous tigecycline.

Journal: The Pediatric infectious disease journal 20100401

Title: Activity of tigecycline against methicillin-resistant Staphylococcus aureus (MRSA) from respiratory tract sources.

Journal: International journal of antimicrobial agents 20100401

Title: Activity of tigecycline against Streptococcus pneumoniae, an important causative pathogen of community-acquired pneumonia (CAP).

Journal: The Journal of infection 20100401

Title: In vitro activity of tigecycline against patient isolates collected during phase 3 clinical trials for diabetic foot infections.

Journal: Diagnostic microbiology and infectious disease 20100401

Title: Clinical experience with tigecycline in the treatment of carbapenem-resistant Acinetobacter infections.

Journal: Journal of chemotherapy (Florence, Italy) 20100401

Title: Differences in determining in vitro tigecycline susceptibility according to the agar medium used.

Journal: Journal of chemotherapy (Florence, Italy) 20100401

Title: [Comparison of disc diffusion, E-test, and broth microdilution methods for the determination of resistance to colistin, polymyxin B, and tigecycline in multi-resistant Acinetobacter baumannii isolates].

Journal: Mikrobiyoloji bulteni 20100401

Title: [Update on antimicrobial chemotherapy].

Journal: Medecine et maladies infectieuses 20100301

Title: Susceptibility to tigecycline of isolates from samples collected in hospitalized patients with secondary peritonitis undergoing surgery.

Journal: Diagnostic microbiology and infectious disease 20100301

Title: Activity of tigecycline against multidrug-resistant clinical isolates of Clostridium spp. from Europe.

Journal: International journal of antimicrobial agents 20100301

Title: Severe and refractory Clostridium difficile infection successfully treated with tigecycline and metronidazole.

Journal: International journal of antimicrobial agents 20100301

Title: Tigecycline resistance in Serratia marcescens associated with up-regulation of the SdeXY-HasF efflux system also active against ciprofloxacin and cefpirome.

Journal: The Journal of antimicrobial chemotherapy 20100301

Title: Cerebral spinal fluid penetration of tigecycline in a patient with Acinetobacter baumannii cerebritis.

Journal: The Annals of pharmacotherapy 20100301

Title: Antimicrobial susceptibility patterns of KPC-producing or CTX-M-producing Enterobacteriaceae.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20100301

Title: Tigecycline in the treatment of ventilator-associated pneumonia: experience from the Latin American Tigecycline Use Registry.

Journal: Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20100301

Title: Comparison of in vitro activities of tigecycline, doxycycline, and tetracycline against the spirochete Borrelia burgdorferi.

Journal: Ticks and tick-borne diseases 20100301

Title: In vitro activity of tigecycline against 2423 clinical isolates and comparison of the available interpretation breakpoints.

Journal: Diagnostic microbiology and infectious disease 20100201

Title: Comparison of the Etest and broth microdilution method for tigecycline susceptibility testing against clinical isolates of Acinetobacter baumannii from Taiwan.

Journal: International journal of antimicrobial agents 20100201

Title: In vitro synergistic activity of tigecycline and colistin against XDR-Acinetobacter baumannii.

Journal: The Journal of antibiotics 20100201

Title: Breakthrough bacteraemia with a susceptible Enterococcus faecalis during tigecycline monotherapy.

Journal: The Journal of antimicrobial chemotherapy 20100201

Title: Newer antibacterial drugs for a new century.

Journal: Expert opinion on investigational drugs 20100201

Title: Sustained antimicrobial activity of tigecycline against methicillin-resistant Staphylococcus aureus (MRSA) from United States Medical Centers from 2004 through 2008.

Journal: Journal of chemotherapy (Florence, Italy) 20100201

Title: Safety and efficacy of intravenous tigecycline in subjects with secondary bacteremia: pooled results from 8 phase III clinical trials.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100115

Title: A novel nano drug delivery system based on tigecycline-loaded calciumphosphate coated with poly-DL-lactide-co-glycolide.

Journal: Journal of materials science. Materials in medicine 20100101

Title: In vitro activity of tigecycline and comparators against a European compilation of anaerobes collected as part of the Tigecycline Evaluation and Surveillance Trial (TEST).

Journal: Scandinavian journal of infectious diseases 20100101

Title: Activity of tigecycline against recent European clinical isolates of Clostridium difficile.

Journal: International journal of antimicrobial agents 20100101

Title: Mutant prevention concentration of tigecycline for carbapenem-susceptible and -resistant Acinetobacter baumannii.

Journal: The Journal of antibiotics 20100101

Title: Disseminated Legionella pneumophila infection in an immunocompromised patient treated with tigecycline.

Journal: Scandinavian journal of infectious diseases 20100101

Title: Vancomycin-resistant Enterococcus spp.: validation of susceptibility testing and in vitro activity of vancomycin, linezolid, tigecycline and daptomycin.

Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20100101

Title: Antimicrobial activity of tigecycline against bacterial isolates from intensive care units in a teaching hospital in Central Saudi Arabia.

Journal: Saudi medical journal 20100101

Title: Francis Tally and the discovery and development of tigecycline: a personal reminiscence.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100101

Title: [In vitro activity of tigecycline in clinical isolates of multidrug resistant Acinetobacter spp. Comparison of different methods of evaluation].

Journal: Revista Argentina de microbiologia 20100101

Title: In vitro activity of tigecycline and other tetracyclines against carbapenem-resistant Acinetobacter species: report from a tertiary care centre in Karachi, Pakistan.

Journal: Chemotherapy 20100101

Title: Evaluation of in vitro activities of tigecycline and various antibiotics against Brucella spp.

Journal: Polish journal of microbiology 20100101

Title: Tigecycline - how powerful is it in the fight against antibiotic-resistant bacteria?

Journal: Medicina (Kaunas, Lithuania) 20100101

Title: Efficacy and safety of tigecycline monotherapy vs. imipenem/cilastatin in Chinese patients with complicated intra-abdominal infections: a randomized controlled trial.

Journal: BMC infectious diseases 20100101

Title: New intravenous antibiotics: a focused pharmacotherapy update.

Journal: AACN advanced critical care 20100101

Title: Prevalence of multidrug-resistant bacteria at a tertiary-care teaching hospital in Mexico: special focus on Acinetobacter baumannii.

Journal: Chemotherapy 20100101

Title: Evolution of tigecycline resistance in Klebsiella pneumoniae in a single patient.

Journal: Annals of Saudi medicine 20100101

Title: Diagnosis of endocarditis caused by Mycobacterium abscessus.

Journal: Annals of Saudi medicine 20100101

Title: Comparative in vitro activity of tigecycline and other antimicrobial agents against Shigella species from Kuwait and the United Arab of Emirates.

Journal: Journal of infection and public health 20100101

Title: Tigecycline use in serious nosocomial infections: a drug use evaluation.

Journal: BMC infectious diseases 20100101

Title: Comparative activity of telavancin and other antimicrobial agents against methicillin-resistant Staphylococcus aureus isolates collected from 1991 to 2006.

Journal: Chemotherapy 20100101

Title: The effect of tigecycline and ertapenem against clinical isolates of Brucella melitensis detected by E-test on different media.

Journal: Indian journal of medical microbiology 20100101

Title: Susceptibility of Escherichia coli and Staphylococcus aureus isolates from a district general hospital in the U.K. to tigecycline and other antimicrobials.

Journal: British journal of biomedical science 20100101

Title: Evaluation of tigecycline activity in clinical isolates among Indian medical centers.

Journal: Indian journal of pathology & microbiology 20100101

Title: Determination of tigecycline in human skin using a novel validated LC-MS/MS method.

Journal: Bioanalysis 20100101

Title: Postantibiotic effects of tigecycline, colistin sulfate, and levofloxacin alone or tigecycline-colistin sulfate and tigecycline-levofloxacin combinations against Acinetobacter baumannii.

Journal: Chemotherapy 20100101

Title: Comparison of the pharmacokinetic properties of vancomycin, linezolid, tigecyclin, and daptomycin.

Journal: European journal of medical research 20100101

Title: Treatment of complicated skin and soft-tissue infections caused by resistant bacteria: value of linezolid, tigecycline, daptomycin and vancomycin.

Journal: European journal of medical research 20100101

Title: Multiresistant bacteria and current therapy - the economical side of the story.

Journal: European journal of medical research 20100101

Title: Comparing in vitro activity of tigecycline by using the disk diffusion test, the manual microdilution method, and the VITEK 2 automated system.

Journal: Revista Argentina de microbiologia 20100101

Title: [Infection with multidrug-resistant pathogens].

Journal: Anestezjologia intensywna terapia 20100101

Title: [Tigecicline susceptibilities of tetracycline-resistant Campylobacter jejuni clinical strains isolated in Poland].

Journal: Medycyna doswiadczalna i mikrobiologia 20100101

Title: Off-label use of antibiotics in hospitalized patients: focus on tigecycline.

Journal: The Journal of antimicrobial chemotherapy 20091201

Title: In vitro activities of moxifloxacin and tigecycline against bacterial isolates associated with intraabdominal infections at a medical center in Taiwan, 2001-2006.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20091201

Title: In vitro effect of physiological concentrations of human albumin on the antibacterial activity of tigecycline.

Journal: The Journal of antimicrobial chemotherapy 20091201

Title: Multidrug-resistant Enterococcus faecium endocarditis treated with combination tigecycline and high-dose daptomycin.

Journal: The Annals of pharmacotherapy 20091201

Title: Macrolides, ketolides, and glycylcyclines: azithromycin, clarithromycin, telithromycin, tigecycline.

Journal: Infectious disease clinics of North America 20091201

Title: In vitro activity of tigecycline against multidrug-resistant Acinetobacter baumannii clinical isolates.

Journal: Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20091201

Title: Tigecycline-induced acute pancreatitis: case report and literature review.

Journal: International journal of antimicrobial agents 20091101

Title: Detection of lfrA and tap efflux pump genes among clinical isolates of non-pigmented rapidly growing mycobacteria.

Journal: International journal of antimicrobial agents 20091101

Title: In vitro activity of tigecycline and comparator agents against a global collection of Gram-negative and Gram-positive organisms: tigecycline Evaluation and Surveillance Trial 2004 to 2007.

Journal: Diagnostic microbiology and infectious disease 20091101

Title: Origin of epidemic clones of acinetobacter in the critically ill.

Journal: The Journal of hospital infection 20091101

Title: Effects of vancomycin, daptomycin, fosfomycin, tigecycline, and ceftriaxone on Staphylococcus epidermidis biofilms.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20091001

Title: Klebsiellapneumoniae isolates possessing KPC beta-lactamase in Israel, Puerto Rico, Colombia and Greece.

Journal: International journal of antimicrobial agents 20091001

Title: New treatments for methicillin-resistant Staphylococcus aureus.

Journal: Current opinion in critical care 20091001

Title: Determination of the pharmacodynamic activity of clinically achievable tigecycline serum concentrations against clinical isolates of Escherichia coli with extended-spectrum beta-lactamases, AmpC beta-lactamases and reduced susceptibility to carbapenems using an in vitro model.

Journal: The Journal of antimicrobial chemotherapy 20091001

Title: Comparison of tigecycline penetration into the epithelial lining fluid of infected and uninfected murine lungs.

Journal: The Journal of antimicrobial chemotherapy 20091001

Title: Multidrug-resistant Gram-negative infections: what are the treatment options?

Journal: Drugs 20091001

Title: Exposure-response analyses of tigecycline tolerability in healthy subjects.

Journal: Diagnostic microbiology and infectious disease 20091001

Title: Tigecycline for the treatment of patients with community-acquired pneumonia requiring hospitalization.

Journal: Expert review of anti-infective therapy 20091001

Title: [Activity of tigecycline on planktonic and sessile cells of Acinetobacter baumannii].

Journal: Mikrobiyoloji bulteni 20091001

Title: [Antimicrobial treatment of nosocomial intra-abdominal infections--new treatment options with tygecycline].

Journal: Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti 20090901

Title: [Therapy of SSTI and role of tigecycline].

Journal: Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20090901

Title: Susceptibility of clinical isolates of frequently encountered bacterial species to tigecycline one year after the introduction of this new class of antibiotics: results of the second multicentre surveillance trial in Germany (G-TEST II, 2007).

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20090801

Title: Antimicrobial susceptibility of tigecycline and comparators against bacterial isolates collected as part of the TEST study in Europe (2004-2007).

Journal: International journal of antimicrobial agents 20090801

Title: Correlation of the expression of acrB and the regulatory genes marA, soxS and ramA with antimicrobial resistance in clinical isolates of Klebsiella pneumoniae endemic to New York City.

Journal: The Journal of antimicrobial chemotherapy 20090801

Title: The tide of antimicrobial resistance and selection.

Journal: International journal of antimicrobial agents 20090801

Title: Unexpected tigecycline resistance among Acinetobacter baumannii Isolates: high minor error rate by Etest.

Journal: Journal of chemotherapy (Florence, Italy) 20090801

Title: Tigecycline in combination with other antimicrobials: a review of in vitro, animal and case report studies.

Journal: International journal of antimicrobial agents 20090701

Title: Tigecycline and colistin susceptibility of Chryseobacterium meningosepticum isolated from blood in Taiwan.

Journal: International journal of antimicrobial agents 20090701

Title: Tigecycline possibly underdosed for the treatment of pneumonia: a pharmacokinetic viewpoint.

Journal: International journal of antimicrobial agents 20090701

Title: Influence of testing methodology on the tigecycline activity profile against presumably tigecycline-non-susceptible Acinetobacter spp.

Journal: The Journal of antimicrobial chemotherapy 20090701

Title: Role of tigecycline in the control of a carbapenem-resistant Acinetobacter baumannii outbreak in an intensive care unit.

Journal: The Journal of hospital infection 20090701

Title: In vitro antibacterial activity of tigecycline against resistant Gram-negative bacilli and enterococci by time-kill assay.

Journal: Diagnostic microbiology and infectious disease 20090701

Title: Tigecycline use in cancer patients with serious infections: a report on 110 cases from a single institution.

Journal: Medicine 20090701

Title: Tigecycline: a new treatment option for intra-abdominal infections.

Journal: Journal of chemotherapy (Florence, Italy) 20090701

Title: Tigecycline for treatment of intra-abdominal infections: a literature update.

Journal: Journal of chemotherapy (Florence, Italy) 20090701

Title: Intravenous tigecycline as adjunctive or alternative therapy for severe refractory Clostridium difficile infection.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090615

Title: Tigecycline has no effect on cytokine release in an ex vivo endotoxin model of human whole blood.

Journal: International journal of antimicrobial agents 20090601

Title: [Multicenter study of in vitro activity of tigecycline in clinical isolates from 30 centers in Spain].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20090601

Title: Comparative in vitro activity of tigecycline and nine other antibiotics against gram-negative bacterial isolates, including ESBL-producing strains.

Journal: Journal of chemotherapy (Florence, Italy) 20090601

Title: Susceptibility of 228 non-fermenting gram-negative rods to tigecycline and six other antimicrobial drugs.

Journal: Journal of chemotherapy (Florence, Italy) 20090601

Title: Successful treatment of Stenotrophomonas maltophilia soft tissue infection with tigecycline: a case report.

Journal: Journal of chemotherapy (Florence, Italy) 20090601

Title: [Multicenter study on the monitoring of in vitro susceptibility to tigeeyeline in Santiago, Chile].

Journal: Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia 20090601

Title: In vitro activities of daptomycin, tigecycline, linezolid and eight other antibiotics, alone and in combination, against 41 Staphylococcus spp. clinical isolates from bone and joint infections.

Journal: International journal of antimicrobial agents 20090501

Title: In vitro activity of tigecycline and 10 other antimicrobials against clinical isolates of the genus Corynebacterium.

Journal: International journal of antimicrobial agents 20090501

Title: Tigecycline and cyclosporine interaction-an interesting case of biliary-excreted drug enhancing the oral bioavailability of cyclosporine.

Journal: European journal of clinical pharmacology 20090501

Title: Reduced susceptibility of multidrug-resistant Acinetobacter baumannii to tigecycline in combination with 1-(1-naphthylmethyl)-piperazine is not a pH-dependent phenomenon.

Journal: The Journal of antimicrobial chemotherapy 20090501

Title: Pharmacodynamic evaluation of tigecycline against Acinetobacter baumannii in a murine pneumonia model.

Journal: The Journal of antimicrobial chemotherapy 20090501

Title: [Comparative study of the in vitro activity of tigecycline against multiresistant Enterococcus faecium isolates].

Journal: Enfermedades infecciosas y microbiologia clinica 20090501

Title: Management of complicated infections in the era of antimicrobial resistance: the role of tigecycline.

Journal: Expert opinion on pharmacotherapy 20090501

Title: In vitro activity of tigecycline against multidrug-resistant Enterobacteriaceae isolates from a Belgian hospital.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20090401

Title: A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecycline.

Journal: The Journal of antimicrobial chemotherapy 20090401

Title: In vitro activity of tigecycline against multiple strains of Borrelia burgdorferi.

Journal: The Journal of antimicrobial chemotherapy 20090401

Title: Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype and revertant strains.

Journal: Antimicrobial agents and chemotherapy 20090401

Title: Tigecycline in the treatment of infections from multi-drug resistant gram-negative pathogens.

Journal: The Journal of infection 20090401

Title: Antimicrobial activity of tigecycline against nosocomial pathogens in Pakistan: a multicenter study.

Journal: JPMA. The Journal of the Pakistan Medical Association 20090401

Title: Comparative in vitro activity of tigecycline against bacteria recovered from clinical specimens in Latin America.

Journal: Journal of chemotherapy (Florence, Italy) 20090401

Title: Tigecycline susceptibility report from an Indian tertiary care hospital.

Journal: The Indian journal of medical research 20090401

Title: [Tigecycline: a systematic review of clinical experience during first years of prescription].

Journal: Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia 20090401

Title: [In vitro activity of tigecycline against methicillin-resistant staphylococci].

Journal: Mikrobiyoloji bulteni 20090401

Title: In vitro activity of tigecycline against colistin-resistant Acinetobacter spp. isolates from Korea.

Journal: International journal of antimicrobial agents 20090301

Title: Impact of biofilm on the in vitro activity of vancomycin alone and in combination with tigecycline and rifampicin against Staphylococcus aureus.

Journal: The Journal of antimicrobial chemotherapy 20090301

Title: Minimum inhibitory concentration of carbapenems and tigecycline against Salmonella spp.

Journal: Journal of medical microbiology 20090301

Title: [Clinical experience with tigecycline in the treatment of nosocomial infections caused by isolates exhibiting prevalent resistance mechanisms].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20090301

Title: [Activity of tigecycline against pathogen bacteria isolated in respiratory infectious disease in Europe. TEST study 2004-2007].

Journal: Pathologie-biologie 20090201

Title: Mycobacterium chelonae necrotizing pneumonia after allogeneic hematopoietic stem cell transplant: report of clinical response to treatment with tigecycline.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20090201

Title: Comparative in vitro activity of tigecycline and other antimicrobials against Gram-negative and Gram-positive organisms collected from the Asia-Pacific Rim as part of the Tigecycline Evaluation and Surveillance Trial (TEST).

Journal: International journal of antimicrobial agents 20090201

Title: Application of patient population-derived pharmacokinetic-pharmacodynamic relationships to tigecycline breakpoint determination for staphylococci and streptococci.

Journal: Diagnostic microbiology and infectious disease 20090201

Title: Activity of novel antibiotic lock solutions in a model against isolates of catheter-related bloodstream infections.

Journal: The Annals of pharmacotherapy 20090201

Title: Treatment of multiresistant Acinetobacter baumannii infections.

Journal: Current opinion in investigational drugs (London, England : 2000) 20090201

Title: Antimicrobial susceptibility among bacterial isolates from ICU and non-ICU setting and different age groups: results from the tigecycline evaluation and Surveillance trial in North America.

Journal: Journal of chemotherapy (Florence, Italy) 20090201

Title: Determining in vitro synergistic activities of tigecycline with several other antibiotics against Brucella melitensis using checkerboard and time-kill assays.

Journal: Journal of chemotherapy (Florence, Italy) 20090201

Title: Late onset ventilator-associated pneumonia due to multidrug-resistant Acinetobacter spp.: experience with tigecycline.

Journal: Journal of chemotherapy (Florence, Italy) 20090201

Title: [Effect of tigecycline on selected multiresistant bacteria].

Journal: Klinicka mikrobiologie a infekcni lekarstvi 20090201

Title: [Tigecycline: Its position between other antibiotics, features, clinical usage].

Journal: Klinicka mikrobiologie a infekcni lekarstvi 20090201

Title: [Tigecycline for treatment of pneumonia].

Journal: Klinicka mikrobiologie a infekcni lekarstvi 20090201

Title: [Pharmacokinetics of tetracyclines and glycylcyclines].

Journal: Klinicka mikrobiologie a infekcni lekarstvi 20090201

Title: Susceptibility of common aerobic pathogens to tigecycline: results of a surveillance study in Germany.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20090101

Title: Tigecycline-induced pancreatitis.

Journal: Journal of clinical gastroenterology 20090101

Title: High serum concentrations of cyclosporin related to administration of tigecycline.

Journal: European journal of clinical pharmacology 20090101

Title: Multicenter study to assess the in vitro activity of tigecycline by disk diffusion test against clinical isolates from Argentina.

Journal: Chemotherapy 20090101

Title: Safety and efficacy of intravenous tigecycline in treatment of community-acquired pneumonia: results from a double-blind randomized phase 3 comparison study with levofloxacin.

Journal: Diagnostic microbiology and infectious disease 20090101

Title: Use of a clinically derived exposure-response relationship to evaluate potential tigecycline-Enterobacteriaceae susceptibility breakpoints.

Journal: Diagnostic microbiology and infectious disease 20090101

Title: Clinical significance of the pharmacokinetic and pharmacodynamic characteristics of tigecycline.

Journal: Current drug metabolism 20090101

Title: Antimicrobial activity of tigecycline and comparative agents against clinical isolates of staphylococci and enterococci from ICUs and general hospital wards at three Swedish university hospitals.

Journal: Scandinavian journal of infectious diseases 20090101

Title: Tigecycline.

Journal: Journal of postgraduate medicine 20090101

Title: Comparison of in vitro activities of tigecycline with other antimicrobial agents against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis in two university hospitals in Istanbul, Turkey.

Journal: Chemotherapy 20090101

Title: Extended-spectrum beta-lactamase Klebsiella pneumoniae meningitis treated with tigecycline.

Journal: Annals of Saudi medicine 20090101

Title: In vitro activity of tigecycline in combination with various antimicrobials against multidrug resistant Acinetobacter baumannii.

Journal: Annals of clinical microbiology and antimicrobials 20090101

Title: A longitudinal analysis of antimicrobial susceptibility in clinical institutions in Germany as part of the Tigecycline Evaluation and Surveillance Trial (2004-2007).

Journal: Chemotherapy 20090101

Title: [Tigecycline: antimicrobial action, chemotherapeutic efficacy and adverse reactions].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20090101

Title: Clinical pharmacokinetics and pharmacodynamics of tigecycline.

Journal: Clinical pharmacokinetics 20090101

Title: Comparative in vitro antimicrobial activity of tigecycline against clinical isolates of vancomycin-resistant enterococcus.

Journal: Indian journal of medical microbiology 20090101

Title: Efficacy and safety of tigecycline versus levofloxacin for community-acquired pneumonia.

Journal: BMC pulmonary medicine 20090101

Title: Tigecycline attenuates staphylococcal superantigen-induced T-cell proliferation and production of cytokines and chemokines.

Journal: Immunopharmacology and immunotoxicology 20090101

Title: [Susceptibility of Enterobacteriaceae rods to selected tetracyclines].

Journal: Medycyna doswiadczalna i mikrobiologia 20090101

Title: One-year experience with tigecycline in treating serious infections in severely burned patients.

Journal: Acta chirurgiae plasticae 20090101

Title: [Tigecycline: in vitro antimicrobial activity in hospitalized patients in an infectology hospital].

Journal: Revista medica del Instituto Mexicano del Seguro Social 20090101

Title: Susceptibility testing of tigecycline against Acinetobacter spp. by disc diffusion method: withdrawing a therapeutic option by varying the Mueller-Hinton agar?

Journal: The Journal of antimicrobial chemotherapy 20081201

Title: Comparative in vitro activity of tigecycline against enterobacteria producing two or more extended-spectrum beta-lactamases.

Journal: International journal of antimicrobial agents 20081201

Title: Tigecycline in vitro activity against commonly encountered multidrug-resistant gram-negative pathogens in a Middle Eastern country.

Journal: Diagnostic microbiology and infectious disease 20081201

Title: Sepsis caused by Elizabethkingia miricola successfully treated with tigecycline and levofloxacin.

Journal: Diagnostic microbiology and infectious disease 20081201

Title: Antimicrobial agents in treatment of MRSA infections.

Journal: Disease-a-month : DM 20081201

Title: Isolation of uncommon respiratory and enteric Acinetobacter baumannii from hematologic patients and emergence of tigecycline-resistance.

Journal: The Journal of infection 20081201

Title: In vitro combinations of five intravenous antibiotics with dalfopristin-quinupristin against Staphylococcus aureus in a 3-dimensional model.

Journal: Journal of chemotherapy (Florence, Italy) 20081201

Title: Tigecycline for treatment of nosocomial-acquired pneumonia possibly caused by multi-drug resistant strains of Stenotrophomonas maltophilia.

Journal: Journal of chemotherapy (Florence, Italy) 20081201

Title: Therapeutic challenges in the era of antibiotic resistance.

Journal: International journal of antimicrobial agents 20081201

Title: A review of tigecycline--the first glycylcycline.

Journal: International journal of antimicrobial agents 20081201

Title: A sensitive human bone assay for quantitation of tigecycline using LC/MS/MS.

Journal: Journal of pharmaceutical and biomedical analysis 20081104

Title: In vitro activity of tigecycline against resistant micro-organisms isolated from burn patients.

Journal: Burns : journal of the International Society for Burn Injuries 20081101

Title: Tigecycline for the treatment of multidrug-resistant Enterobacteriaceae: a systematic review of the evidence from microbiological and clinical studies.

Journal: The Journal of antimicrobial chemotherapy 20081101

Title: Comment on: Effect of different Mueller-Hinton agars on tigecycline disc diffusion susceptibility for Acinetobacter spp.

Journal: The Journal of antimicrobial chemotherapy 20081101

Title: In vitro activity of tigecycline against gram-positive cocci: a multicentre study in Greece.

Journal: The Journal of antimicrobial chemotherapy 20081101

Title: Non-susceptibility trends among staphylococci from bacteraemias in the UK and Ireland, 2001-06.

Journal: The Journal of antimicrobial chemotherapy 20081101

Title: Comment: tigecycline for the treatment of Acinetobacter infections: a case series.

Journal: The Annals of pharmacotherapy 20081101

Title: Tigecycline in-vitro susceptibility and antibiotics' fitness for gram-negative pathogens.

Journal: Saudi medical journal 20081101

Title: Tigecycline In-vitro Surveillance in Taiwan (TIST).

Journal: International journal of antimicrobial agents 20081101

Title: Nationwide surveillance in Taiwan of the in-vitro activity of tigecycline against clinical isolates of extended-spectrum beta-lactamase-producing Enterobacteriaceae.

Journal: International journal of antimicrobial agents 20081101

Title: Nationwide surveillance in Taiwan of the in-vitro activity of tigecycline against clinical isolates of Gram-positive cocci.

Journal: International journal of antimicrobial agents 20081101

Title: In-vitro activity of tigecycline against clinical isolates of Acinetobacter baumannii in Taiwan.

Journal: International journal of antimicrobial agents 20081101

Title: In-vitro activity of tigecycline against clinical isolates of Acinetobacter baumannii in Taiwan determined by the broth microdilution and disk diffusion methods.

Journal: International journal of antimicrobial agents 20081101

Title: Update on antimicrobial susceptibility rates among gram-negative and gram-positive organisms in the United States: results from the Tigecycline Evaluation and Surveillance Trial (TEST) 2005 to 2007.

Journal: Clinical therapeutics 20081101

Title: Effect of different Mueller-Hinton agars on tigecycline disc diffusion susceptibility for Acinetobacter spp.

Journal: The Journal of antimicrobial chemotherapy 20081001

Title: Usefulness of the Etest for studying tigecycline susceptibility of non-pigmented rapidly growing mycobacteria.

Journal: International journal of antimicrobial agents 20081001

Title: In vitro activity of ceftobiprole, linezolid, tigecycline, and 23 other antimicrobial agents against Staphylococcus aureus isolates in China.

Journal: Diagnostic microbiology and infectious disease 20081001

Title: The challenge of multidrug resistance: the treatment of gram-negative rod infections.

Journal: Shock (Augusta, Ga.) 20081001

Title: Establishing the role of tigecycline in an era of antimicrobial resistance.

Journal: Expert review of anti-infective therapy 20081001

Title: Serious staphylococcal infections.

Journal: Clinical medicine (London, England) 20081001

Title: In vitro activity of tigecycline: MICs, MBCs, time-kill curves and post-antibiotic effect.

Journal: Journal of chemotherapy (Florence, Italy) 20081001

Title: A review of tigecycline.

Journal: Journal of chemotherapy (Florence, Italy) 20081001

Title: The efficacy and safety of tigecycline for the treatment of complicated intra-abdominal infections - the European experience.

Journal: Journal of chemotherapy (Florence, Italy) 20081001

Title: Overview of tigecycline efficacy and safety in the treatment of complicated skin and skin structure infections - a European perspective.

Journal: Journal of chemotherapy (Florence, Italy) 20081001

Title: Tigecycline versus levofloxacin for the treatment of community-acquired pneumonia: European experience.

Journal: Journal of chemotherapy (Florence, Italy) 20081001

Title: In vitro activity of tigecycline as a therapeutic option against multidrug-resistant Acinetobacter spp.

Journal: The new microbiologica 20081001

Title: Rates of antimicrobial resistance in Latin America (2004-2007) and in vitro activity of the glycylcycline tigecycline and of other antibiotics.

Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20081001

Title: Tigecycline for the treatment of Acinetobacter infections: a case series.

Journal: The Annals of pharmacotherapy 20080901

Title: Pilot trial of N-acetylcysteine and tigecycline as a catheter-lock solution for treatment of hemodialysis catheter-associated bacteremia.

Journal: Infection control and hospital epidemiology 20080901

Title: Tigecycline pharmacokinetic/pharmacodynamic update.

Journal: The Journal of antimicrobial chemotherapy 20080901

Title: Efficacy and safety of tigecycline compared with vancomycin or linezolid for treatment of serious infections with methicillin-resistant Staphylococcus aureus or vancomycin-resistant enterococci: a Phase 3, multicentre, double-blind, randomized study.

Journal: The Journal of antimicrobial chemotherapy 20080901

Title: A Phase 3, open-label, non-comparative study of tigecycline in the treatment of patients with selected serious infections due to resistant Gram-negative organisms including Enterobacter species, Acinetobacter baumannii and Klebsiella pneumoniae.

Journal: The Journal of antimicrobial chemotherapy 20080901

Title: In vitro activity of tigecycline and occurrence of tetracycline resistance determinants in isolates from patients enrolled in phase 3 clinical trials for community-acquired pneumonia.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080901

Title: In vitro activity of tigecycline against multidrug-resistant Acinetobacter baumannii.

Journal: The Journal of antimicrobial chemotherapy 20080801

Title: Meticillin-resistant Staphylococcus aureus hepatic abscess treated with tigecycline.

Journal: Journal of clinical pathology 20080801

Title: Tigecycline: a new antibiotic.

Journal: Intensive & critical care nursing 20080801

Title: Tigecycline: a critical update.

Journal: Journal of chemotherapy (Florence, Italy) 20080801

Title: What role for tigecycline in infections?

Journal: Drug and therapeutics bulletin 20080801

Title: In vitro activity of tigecycline against clinical isolates of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae, Serratia marcescens and Enterobacter cloacae.

Journal: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20080801

Title: Effect of porin loss on the activity of tigecycline against Klebsiella pneumoniae producing extended-spectrum beta-lactamases or plasmid-mediated AmpC-type beta-lactamases.

Journal: Diagnostic microbiology and infectious disease 20080701

Title: Tigecycline for treating bloodstream infections: a critical analysis of the available evidence.

Journal: Diagnostic microbiology and infectious disease 20080701

Title: Concordance of interrater assessments of surgical methods to achieve source control of intra-abdominal infections.

Journal: American journal of surgery 20080701

Title: Tigecycline for the treatment of multidrug-resistant (including carbapenem-resistant) Acinetobacter infections: a review of the scientific evidence.

Journal: The Journal of antimicrobial chemotherapy 20080701

Title: Integrated results of 2 phase 3 studies comparing tigecycline and levofloxacin in community-acquired pneumonia.

Journal: Diagnostic microbiology and infectious disease 20080701

Title: Colistin and tigecycline susceptibility among multidrug-resistant Acinetobacter baumannii isolated from ventilator-associated pneumonia.

Journal: International journal of antimicrobial agents 20080701

Title: Evaluation of a potential tigecycline-warfarin drug interaction.

Journal: Pharmacotherapy 20080701

Title: Multidrug-resistant Acinetobacter baumannii pneumonia in lung transplant recipients.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080701

Title: Health care-associated pneumonia: identification and initial management in the ED.

Journal: The American journal of emergency medicine 20080701

Title: Effects of tigecycline and daptomycin on murine gut colonization by Candida albicans.

Journal: Mycoses 20080701

Title: Multidrug-resistant Klebsiella pneumoniae mediastinitis safely and effectively treated with prolonged administration of tigecycline.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080615

Title: Tigecycline for Acinetobacter baumannii infection: other considerations.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080601

Title: [New antibiotics].

Journal: La Revue de medecine interne 20080601

Title: In vitro activities of linezolid and tigecycline against methicillin-resistant Staphylococcus aureus strains.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20080601

Title: [Skin and soft tissue infections: current therapeutic options].

Journal: Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20080601

Title: Tigecycline: a new treatment choice against Acinetobacter baumannii.

Journal: Recent patents on anti-infective drug discovery 20080601

Title: Indications of a new antibiotic in clinical practice: results of the tigecycline initial use registry.

Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20080601

Title: New antimicrobial agents for the treatment of Gram-positive bacterial infections.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080501

Title: Tigecycline-resistant Enterococcus faecalis strain isolated from a German intensive care unit patient.

Journal: The Journal of antimicrobial chemotherapy 20080501

Title: Antimicrobial activity of tigecycline against community-acquired methicillin-resistant Staphylococcus aureus isolates recovered from North American medical centers.

Journal: Diagnostic microbiology and infectious disease 20080401

Title: Tigecycline activity tested against 11808 bacterial pathogens recently collected from US medical centers.

Journal: Diagnostic microbiology and infectious disease 20080401

Title: Comparative analysis of antimicrobial susceptibility among organisms from France, Germany, Italy, Spain and the UK as part of the tigecycline evaluation and surveillance trial.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080401

Title: Tigecycline in critical care.

Journal: Critical care clinics 20080401

Title: [New anti-Gram+antibiotics: which role in infective endocarditis?].

Journal: Annales de cardiologie et d'angeiologie 20080401

Title: [In vitro activity of tigecycline against multiple resistant Acinetobacter baumannii and carbapenem resistant Klebsiella pneumoniae isolates].

Journal: Mikrobiyoloji bulteni 20080401

Title: Evaluation of the in vitro activity of tigecycline against multiresistant Gram-positive cocci containing tetracycline resistance determinants.

Journal: International journal of antimicrobial agents 20080301

Title: Use of tigecycline for the treatment of prolonged bacteremia due to a multiresistant VIM-1 and SHV-12 beta--lactamase-producing Klebsiella pneumoniae epidemic clone.

Journal: Diagnostic microbiology and infectious disease 20080301

Title: Tigecycline for the treatment of patients with severe sepsis or septic shock: a drug use evaluation in a surgical intensive care unit.

Journal: The Journal of antimicrobial chemotherapy 20080301

Title: [Use of a program-specific website to disseminate data on antimicrobial susceptibility of clinical isolates from the Tigecycline Evaluation and Surveillance Trial (TEST)].

Journal: Medecine et maladies infectieuses 20080301

Title: In vitro activity of cefepime, imipenem, tigecycline, and gentamicin, alone and in combination, against extended-spectrum beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.

Journal: Pharmacotherapy 20080301

Title: Therapeutic options for Acinetobacter baumannii infections.

Journal: Expert opinion on pharmacotherapy 20080301

Title: Multidrug-resistant Acinetobacter baumannii osteomyelitis from Iraq.

Journal: Emerging infectious diseases 20080301

Title: Clinical and microbiological outcomes of serious infections with multidrug-resistant gram-negative organisms treated with tigecycline.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080215

Title: In vitro activities of tigecycline combined with other antimicrobials against multiresistant gram-positive and gram-negative pathogens.

Journal: The Journal of antimicrobial chemotherapy 20080201

Title: Comparative bactericidal activities of daptomycin, glycopeptides, linezolid and tigecycline against blood isolates of Gram-positive bacteria in Taiwan.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080201

Title: The current state of multidrug-resistant gram-negative bacilli in North America.

Journal: Pharmacotherapy 20080201

Title: Acinetobacter baumannii: an emerging multidrug-resistant pathogen in critical care.

Journal: Critical care nurse 20080201

Title: Comparison of the efficacy of tigecycline and teicoplanin in an experimental methicillin-resistant Staphylococcus aureus osteomyelitis model.

Journal: Journal of chemotherapy (Florence, Italy) 20080201

Title: A pharmacodynamic simulation to assess tigecycline efficacy for hospital-acquired pneumonia compared with other common intravenous antibiotics.

Journal: Journal of chemotherapy (Florence, Italy) 20080201

Title: Pharmacodynamic performance of tigecycline versus common intravenous antibiotics for the empiric treatment of complicated skin and skin structure infections.

Journal: Surgical infections 20080201

Title: [Pharmacological rationale for choice of antibiotics for intraabdominal infections].

Journal: Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20080201

Title: [New options for treatment of intraabdominal infections: tigecycline].

Journal: Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20080201

Title: In vitro activity of tigecycline, tetracycline and fluoroquinolones against Brucella melitensis.

Journal: Journal of chemotherapy (Florence, Italy) 20080201

Title: Effect of the anticoagulant ethylenediamine tetra-acetic acid (EDTA) on the estimation of pharmacokinetic parameters: A case study with tigecycline and ciprofloxacin.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20080101

Title: MarA-mediated overexpression of the AcrAB efflux pump results in decreased susceptibility to tigecycline in Escherichia coli.

Journal: The Journal of antimicrobial chemotherapy 20080101

Title: Tigecycline in vitro activity against gram-negative and gram-positive pathogens collected in Italy.

Journal: Chemotherapy 20080101

Title: Other antimicrobials of interest in the era of extended-spectrum beta-lactamases: fosfomycin, nitrofurantoin and tigecycline.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080101

Title: In vitro activity of tigecycline and comparators against carbapenem-susceptible and resistant Acinetobacter baumannii clinical isolates in Italy.

Journal: Annals of clinical microbiology and antimicrobials 20080101

Title: Baseline in vitro activity of tigecycline among key bacterial pathogens exhibiting multidrug resistance.

Journal: Chemotherapy 20080101

Title: [New antimicrobials against Gram-positive organisms].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20080101

Title: Acute pancreatitis related to tigecycline: case report and review of the literature.

Journal: Scandinavian journal of infectious diseases 20080101

Title: Tigecycline: in community-acquired pneumonia.

Journal: Drugs 20080101

Title: Use of in vitro susceptibility and pathogen prevalence data to model the expected clinical success rates of tigecycline and other commonly used antimicrobials for empirical treatment of complicated skin and skin-structure infections.

Journal: International journal of antimicrobial agents 20071201

Title: [Treatment of a septic shock due to multiresistant Acinetobacter baumannii with tigecycline in combination].

Journal: Annales francaises d'anesthesie et de reanimation 20071201

Title: In vitro activity of tigecycline against metallo-beta-lactamase-producing Enterobacteriaceae.

Journal: The Journal of antimicrobial chemotherapy 20071201

Title: In vitro activities of 'new' and 'conventional' antibiotics against multi-drug resistant Gram negative bacteria from patients in the intensive care unit.

Journal: Pathology 20071201

Title: Successful treatment of multi-resistant Pseudomonas aeruginosa osteomyelitis after allogeneic bone marrow transplantation with a combination of colistin and tigecycline.

Journal: Journal of medical microbiology 20071201

Title: Update on prevalence and treatment of methicillin-resistant Staphylococcus aureus infections.

Journal: Expert review of anti-infective therapy 20071201

Title: Treatment of anaerobic infection.

Journal: Expert review of anti-infective therapy 20071201

Title: Optimizing therapy for MRSA pneumonia.

Journal: Seminars in respiratory and critical care medicine 20071201

Title: Optimizing therapy for Acinetobacter baumannii.

Journal: Seminars in respiratory and critical care medicine 20071201

Title: [Initial use of tigecycline in Argentina].

Journal: Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia 20071201

Title: Single daily high-dose tigecycline therapy of a multidrug-resistant (MDR) Klebsiella pneumoniae and Enterobacter aerogenes nosocomial urinary tract infection.

Journal: Journal of chemotherapy (Florence, Italy) 20071201

Title: [Therapeutic efficacy, animal models and experimental pharmacodynamics: what do we know about tigecycline?].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20071201

Title: Antimicrobial activity of mupirocin, daptomycin, linezolid, quinupristin/dalfopristin and tigecycline against vancomycin-resistant enterococci (VRE) from clinical isolates in Korea (1998 and 2005).

Journal: Journal of biochemistry and molecular biology 20071130

Title: In vitro antibacterial activities of tigecycline and comparative agents by time-kill kinetic studies in fresh Mueller-Hinton broth.

Journal: Diagnostic microbiology and infectious disease 20071101

Title: In vitro activity of daptomycin and tigecycline against coagulase-negative staphylococcus blood isolates from bone marrow transplant recipients.

Journal: European journal of haematology 20071101

Title: Antimicrobial susceptibility among organisms from the Asia/Pacific Rim, Europe and Latin and North America collected as part of TEST and the in vitro activity of tigecycline.

Journal: The Journal of antimicrobial chemotherapy 20071101

Title: In vitro activity of tigecycline against strains isolated from diabetic foot ulcers.

Journal: Pathologie-biologie 20071101

Title: Evidence for low risk of Clostridium difficile infection associated with tigecycline.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20071001

Title: Determination of disc breakpoints and evaluation of Etests for tigecycline susceptibility testing by the BSAC method.

Journal: The Journal of antimicrobial chemotherapy 20071001

Title: Daptomycin and tigecycline: a review of clinical efficacy in the antimicrobial era.

Journal: Expert opinion on pharmacotherapy 20071001

Title: Distribution of resistant gram-positive organisms across the census regions of the United States and in vitro activity of tigecycline, a new glycylcycline antimicrobial.

Journal: American journal of infection control 20071001

Title: Susceptibility of multi-resistant Gram-negative bacilli in Singapore to tigecycline as tested by agar dilution.

Journal: Annals of the Academy of Medicine, Singapore 20071001

Title: Selecting anti-infective agents for the treatment of bone infections: new anti-infective agents and chronic suppressive therapy.

Journal: Orthopedics 20071001

Title: Comparative in vitro activity of tigecycline against aerobic and facultative isolates recovered from hospitalized patients: an Argentinean multicenter study.

Journal: Journal of chemotherapy (Florence, Italy) 20071001

Title: Metabolism, excretion, and pharmacokinetics of [14C]tigecycline, a first-in-class glycylcycline antibiotic, after intravenous infusion to healthy male subjects.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070901

Title: Prevalence and regional variation in meticillin-resistant Staphylococcus aureus (MRSA) in the USA and comparative in vitro activity of tigecycline, a glycylcycline antimicrobial.

Journal: Journal of medical microbiology 20070901

Title: Effects of tigecycline, linezolid and vancomycin on biofilms of viridans streptococci isolates from patients with endocarditis.

Journal: The International journal of artificial organs 20070901

Title: Linezolid- and vancomycin-resistant Enterococcus faecium endocarditis: successful treatment with tigecycline and daptomycin.

Journal: Journal of hospital medicine 20070901

Title: A novel antibiotic bone assay by liquid chromatography/tandem mass spectrometry for quantitation of tigecycline in rat bone.

Journal: Journal of pharmaceutical and biomedical analysis 20070815

Title: In vitro antibacterial activity of tigecycline in comparison with doxycycline, ciprofloxacin and rifampicin against Brucella spp.

Journal: International journal of antimicrobial agents 20070801

Title: A comparison of the activity of tigecycline against multiresistant clinical isolates of Staphylococcus aureus and Streptococcus agalactiae.

Journal: Diagnostic microbiology and infectious disease 20070801

Title: In vitro activities of carbapenem/sulbactam combination, colistin, colistin/rifampicin combination and tigecycline against carbapenem-resistant Acinetobacter baumannii.

Journal: The Journal of antimicrobial chemotherapy 20070801

Title: Acinetobacter spp. susceptibility to tigecycline: a worldwide perspective.

Journal: The Journal of antimicrobial chemotherapy 20070801

Title: Rapid development of Acinetobacter baumannii resistance to tigecycline.

Journal: Pharmacotherapy 20070801

Title: Empiric treatment options in the management of complicated intra-abdominal infections.

Journal: Cleveland Clinic journal of medicine 20070801

Title: A combination of mathematical and statistical models to distinguish between 'susceptible' and 'resistant' clusters in the susceptibility disk diffusion method.

Journal: Journal of chemotherapy (Florence, Italy) 20070801

Title: Antimicrobial susceptibility among Acinetobacter calcoaceticus-baumannii complex and Enterobacteriaceae collected as part of the Tigecycline Evaluation and Surveillance Trial.

Journal: The Journal of infection 20070701

Title: Comment on: High tigecycline resistance in multidrug-resistant Acinetobacter baumannii.

Journal: The Journal of antimicrobial chemotherapy 20070701

Title: Diffuse cutaneous hyperpigmentation due to tigecycline or polymyxin B.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070701

Title: Synergy testing of multidrug resistant Acinetobacter baumanii against tigecycline and polymyxin using an E-test methodology.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20070701

Title: In vitro activity of ten antibiotics, including tigecycline, against Bacteroides species in Austria.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20070701

Title: Early experience with tigecycline for ventilator-associated pneumonia and bacteremia caused by multidrug-resistant Acinetobacter baumannii.

Journal: Pharmacotherapy 20070701

Title: Tigecycline for treatment of pneumonia and empyema caused by carbapenemase-producing Klebsiella pneumoniae.

Journal: Pharmacotherapy 20070701

Title: Tigecycline: a novel broad-spectrum antimicrobial.

Journal: The Annals of pharmacotherapy 20070601

Title: Population pharmacokinetics of tigecycline in healthy volunteers.

Journal: Journal of clinical pharmacology 20070601

Title: Absence of an interaction between tigecycline and digoxin in healthy men.

Journal: Pharmacotherapy 20070601

Title: Combating the growing problem of methicillin-resistant Staphylococcus aureus: do the newer antibiotics represent a better alternative to vancomycin?

Journal: Expert review of anti-infective therapy 20070601

Title: Part X. Tetracycline and glycylcycline antimicrobials.

Journal: The Journal of the Oklahoma State Medical Association 20070601

Title: AdeABC multidrug efflux pump is associated with decreased susceptibility to tigecycline in Acinetobacter calcoaceticus-Acinetobacter baumannii complex.

Journal: The Journal of antimicrobial chemotherapy 20070501

Title: Influence of polysorbate-80 when determining the tigecycline MIC by the reference method.

Journal: Diagnostic microbiology and infectious disease 20070501

Title: Regional variations in multidrug resistance among Enterobacteriaceae in the USA and comparative activity of tigecycline, a new glycylcycline antimicrobial.

Journal: International journal of antimicrobial agents 20070501

Title: Therapeutic applications of tigecycline in the management of complicated skin and skin structure infections.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20070501

Title: High tigecycline resistance in multidrug-resistant Acinetobacter baumannii.

Journal: The Journal of antimicrobial chemotherapy 20070401

Title: Tigecycline resistance in Australian antibiotic-resistant Gram-negative bacteria.

Journal: The Journal of antimicrobial chemotherapy 20070401

Title: Tigecycline: in-vitro performance as a predictor of clinical efficacy.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20070401

Title: Antimicrobial susceptibility of extended-spectrum beta-lactamase producers and multidrug-resistant Acinetobacter baumannii throughout the United States and comparative in vitro activity of tigecycline, a new glycylcycline antimicrobial.

Journal: Diagnostic microbiology and infectious disease 20070401

Title: E-test minimum inhibitory concentrations for tigecycline against nosocomial Acinetobacter baumannii strains.

Journal: Journal of chemotherapy (Florence, Italy) 20070401

Title: Once-daily tigecycline therapy of multidrug-resistant and non-multidrug-resistant gram-negative bacteremias.

Journal: Journal of chemotherapy (Florence, Italy) 20070401

Title: Predictors of efficacy and health resource utilization in treatment of complicated intra-abdominal infections: evidence for pooled clinical studies comparing tigecycline with imipenem-cilastatin.

Journal: Surgical infections 20070401

Title: Tigecycline (GAR-936) activity against Streptococcus gallolyticus (bovis) and viridans group streptococci.

Journal: Diagnostic microbiology and infectious disease 20070301

Title: In vitro activity of tigecycline against clinical isolates of Acinetobacter baumannii and Stenotrophomonas maltophilia.

Journal: The Journal of antimicrobial chemotherapy 20070301

Title: In vitro activities of tigecycline, daptomycin, linezolid and quinupristin/dalfopristin against glycopeptide-resistant Enterococcus faecium.

Journal: International journal of antimicrobial agents 20070301

Title: In vitro activity of tigecycline against carbapenem-susceptible and -resistant isolates of Klebsiella spp. and Enterobacter spp.

Journal: The Journal of antimicrobial chemotherapy 20070301

Title: [Therapeutic perspectives of linezolid in the management of infections due to multiresistant Gram-positive pathogens].

Journal: Recenti progressi in medicina 20070301

Title: [Tigecycline, the first of a new class of antibiotics: the glycylcyclines].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20070301

Title: In vitro activity of tigecycline against quinolone-resistant Streptococcus pneumoniae, methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci.

Journal: International journal of antimicrobial agents 20070201

Title: [Septic shock due to vancomycin-resistant enterococci infection. Tigecycline monotherapy].

Journal: Der Anaesthesist 20070201

Title: Tigecycline use in critically ill older patients: case reports and critical analysis.

Journal: Journal of the American Geriatrics Society 20070201

Title: Acinetobacter baumannii bloodstream infection while receiving tigecycline: a cautionary report.

Journal: The Journal of antimicrobial chemotherapy 20070101

Title: Tigecycline: a single antibiotic for polymicrobial infections.

Journal: The Pediatric infectious disease journal 20070101

Title: New antibiotics, efflux pumps and overcoming resistance.

Journal: Casopis lekaru ceskych 20070101

Title: Tigecycline: its potential for treatment of brucellosis.

Journal: Scandinavian journal of infectious diseases 20070101

Title: RamA, a transcriptional regulator, and AcrAB, an RND-type efflux pump, are associated with decreased susceptibility to tigecycline in Enterobacter cloacae.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20070101

Title: Treatment of infections caused by resistant Staphylococcus aureus.

Journal: Methods in molecular biology (Clifton, N.J.) 20070101

Title: Multidrug resistant Acinetobacter nosocomial meningitis treated successfully with parenteral tigecycline.

Journal: Annals of Saudi medicine 20070101

Title: Antimicrobial activity of tigecycline against clinical isolates from Spanish medical centers. Second multicenter study.

Journal: Diagnostic microbiology and infectious disease 20061201

Title: Serum, tissue and body fluid concentrations of tigecycline after a single 100 mg dose.

Journal: The Journal of antimicrobial chemotherapy 20061201

Title: Activity of tigecycline against ESBL-producing and AmpC-hyperproducing Enterobacteriaceae from south-east England.

Journal: The Journal of antimicrobial chemotherapy 20061201

Title: Activity of tigecycline against clinical isolates of Staphylococcus aureus and extended-spectrum beta-lactamase-producing Escherichia coli in Granada, Spain.

Journal: International journal of antimicrobial agents 20061201

Title: Tigecycline: a new glycylcycline antimicrobial.

Journal: International journal of clinical practice 20061201

Title: Tigecycline: the answer to beta-lactam and fluoroquinolone resistance?

Journal: The Journal of infection 20061101

Title: Comparative in vitro activities of tigecycline and 11 other antimicrobial agents against 215 epidemiologically defined multidrug-resistant Acinetobacter baumannii isolates.

Journal: The Journal of antimicrobial chemotherapy 20061101

Title: Tigecycline does not induce proliferation or cytotoxin production by epidemic Clostridium difficile strains in a human gut model.

Journal: The Journal of antimicrobial chemotherapy 20061101

Title: Activity of tigecycline in the treatment of acute Burkholderia pseudomallei infection in a murine model.

Journal: International journal of antimicrobial agents 20061101

Title: Peritoneal fluid penetration of tigecycline.

Journal: The Annals of pharmacotherapy 20061101

Title: Successful salvage therapy with tigecycline after linezolid failure in a liver transplant recipient with MRSA pneumonia.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20061101

Title: EUCAST technical note on tigecycline.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20061101

Title: In vitro activity of tigecycline against clinical isolates of multidrug-resistant Acinetobacter baumannii in Siriraj Hospital, Thailand.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20061101

Title: Clinical experience with recently approved antibiotics.

Journal: Current opinion in pharmacology 20061001

Title: Challenges in identifying new antimicrobial agents effective for treating infections with Acinetobacter baumannii and Pseudomonas aeruginosa.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060901

Title: [Bacterial resistance and a new antibiotic: tigecycline].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20060901

Title: Tigecycline: a critical analysis.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060815

Title: Antimicrobial activity of tigecycline against recent isolates of respiratory pathogens from Asian countries.

Journal: Diagnostic microbiology and infectious disease 20060801

Title: Case studies in current drug development: 'glycylcyclines'.

Journal: Current opinion in chemical biology 20060801

Title: Tigecycline: first of a new class of antimicrobial agents.

Journal: Pharmacotherapy 20060801

Title: New drugs 06, part II.

Journal: Nursing 20060801

Title: Tigecycline: a glycylcycline antimicrobial agent.

Journal: Clinical therapeutics 20060801

Title: New 'superbug' drug launched in the UK.

Journal: Future microbiology 20060801

Title: In vitro activities of tigecycline against recently isolated Gram-negative anaerobic bacteria in Greece, including metronidazole-resistant strains.

Journal: Diagnostic microbiology and infectious disease 20060701

Title: Tigecycline: place in therapy and important considerations.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060701

Title: Tigecycline: a new glycylcycline antimicrobial agent.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060701

Title: Antibacterial drug discovery and development--SRI's 11th Annual Summit.

Journal: IDrugs : the investigational drugs journal 20060601

Title: Overview of tigecycline and its role in the era of antibiotic resistance.

Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20060601

Title: [Treatment with the first glycylcycline--tigecycline].

Journal: Medizinische Monatsschrift fur Pharmazeuten 20060501

Title: Mycobacterium abscessus: an emerging rapid-growing potential pathogen.

Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20060501

Title: In vitro activity of tigecycline (GAR-936) and other antimicrobials against tetracycline- and ciprofloxacin-resistant Campylobacter clinical isolates.

Journal: International journal of antimicrobial agents 20060401

Title: Successful treatment of septic shock due to pan-resistant Acinetobacter baumannii using combined antimicrobial therapy including tigecycline.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20060401

Title: Practical considerations of new drugs: new choices for old problems.

Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20060401

Title: Antibiotics for treatment of resistant gram-positive coccal infections.

Journal: Indian journal of pediatrics 20060401

Title: Epidemiological MIC cut-off values for tigecycline calculated from Etest MIC values using normalized resistance interpretation.

Journal: The Journal of antimicrobial chemotherapy 20060301

Title: In vitro antibacterial activities of tigecycline in combination with other antimicrobial agents determined by chequerboard and time-kill kinetic analysis.

Journal: The Journal of antimicrobial chemotherapy 20060301

Title: Tigecycline for the treatment of infections due to resistant Gram-positive organisms.

Journal: Expert opinion on investigational drugs 20060201

Title: Tigecycline: a novel glycylcycline antibiotic.

Journal: Expert review of anti-infective therapy 20060201

Title: An update on tetracyclines.

Journal: Current opinion in investigational drugs (London, England : 2000) 20060201

Title: Tigecycline and the need for a new broad-spectrum antibiotic class.

Journal: Surgical infections 20060201

Title: Synthesis and antibacterial activity of 9-substituted minocycline derivatives.

Journal: Bioorganic & medicinal chemistry letters 20060115

Title: Tigecycline (Tygacil).

Journal: Obstetrics and gynecology 20060101

Title: Comparison of in vitro activities of tigecycline with other antimicrobial agents against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in Taiwan.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20060101

Title: Four cases of invasive methicillin-resistant Staphylococcus aureus (MRSA) infections treated with tigecycline.

Journal: Scandinavian journal of infectious diseases 20060101

Title: Effect of medium type, age and aeration on the MICs of tigecycline and classical tetracyclines.

Journal: The Journal of antimicrobial chemotherapy 20051201

Title: The search for new antimicrobials: why we need new options.

Journal: Expert review of anti-infective therapy 20051201

Title: Tigecycline: what is it, and where should it be used?

Journal: The Journal of antimicrobial chemotherapy 20051001

Title: New antibiotics for the treatment of severe staphylococcal infection in the critically ill patient.

Journal: Current opinion in critical care 20051001

Title: Tigecycline.

Journal: Nature reviews. Drug discovery 20051001

Title: Tigecycline: a review of preclinical and clinical studies of the first-in-class glycylcycline antibiotic.

Journal: Drugs of today (Barcelona, Spain : 1998) 20051001

Title: In vitro activity of tigecycline, a new glycylcycline, tested against 1,326 clinical bacterial strains isolated from Latin America.

Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20051001

Title: New drugs and dosage forms.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050915

Title: Tigecycline (tygacil).

Journal: The Medical letter on drugs and therapeutics 20050912

Title: Tigecycline is modified by the flavin-dependent monooxygenase TetX.

Journal: Biochemistry 20050906

Title: Penetration, efflux and intracellular activity of tigecycline in human polymorphonuclear neutrophils (PMNs).

Journal: The Journal of antimicrobial chemotherapy 20050901

Title: Tigecycline.

Journal: The Journal of antimicrobial chemotherapy 20050901

Title: Overview of antibiotic use and resistance: setting the stage for tigecycline.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050901

Title: Tigecycline: a new glycylcycline for treatment of serious infections.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050901

Title: In vitro activity of tigecycline against isolates from patients enrolled in phase 3 clinical trials of treatment for complicated skin and skin-structure infections and complicated intra-abdominal infections.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050901

Title: The pharmacokinetic and pharmacodynamic profile of tigecycline.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050901

Title: The efficacy and safety of tigecycline in the treatment of skin and skin-structure infections: results of 2 double-blind phase 3 comparison studies with vancomycin-aztreonam.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050901

Title: The efficacy and safety of tigecycline for the treatment of complicated intra-abdominal infections: analysis of pooled clinical trial data.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050901

Title: Efficacy and safety of tigecycline monotherapy compared with vancomycin plus aztreonam in patients with complicated skin and skin structure infections: Results from a phase 3, randomized, double-blind trial.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20050901

Title: In vitro activity of tigecycline against Bacteroides species.

Journal: The Journal of antimicrobial chemotherapy 20050801

Title: New antibiotic approved for MRSA.

Journal: The Lancet. Infectious diseases 20050801

Title: Tigecyclin--the first glycylcycline to undergo clinical development: an overview of in vitro activity compared to tetracycline.

Journal: Journal of chemotherapy (Florence, Italy) 20050801

Title: Pharmacokinetics, pharmacodynamics, safety and tolerability of tigecycline.

Journal: Journal of chemotherapy (Florence, Italy) 20050801

Title: Efficacy of tigecycline in complicated skin and skin structure infections and complicated intra-abdominal infections.

Journal: Journal of chemotherapy (Florence, Italy) 20050801

Title: Tigecycline: an expanded broad-spectrum intravenous antibiotic. Preface and summary.

Journal: Journal of chemotherapy (Florence, Italy) 20050801

Title: Antimicrobial activity and pharmacokinetics/pharmacodynamics of the novel glycylcycline, tigecycline.

Journal: Diagnostic microbiology and infectious disease 20050701

Title: Pharmacokinetic/pharmacodynamic profile for tigecycline-a new glycylcycline antimicrobial agent.

Journal: Diagnostic microbiology and infectious disease 20050701

Title: In vitro activity of tigecycline against 3989 Gram-negative and Gram-positive clinical isolates from the United States Tigecycline Evaluation and Surveillance Trial (TEST Program; 2004).

Journal: Diagnostic microbiology and infectious disease 20050701

Title: Tigecycline activity tested against 26,474 bloodstream infection isolates: a collection from 6 continents.

Journal: Diagnostic microbiology and infectious disease 20050701

Title: Antimicrobial activity of tigecycline tested against organisms causing community-acquired respiratory tract infection and nosocomial pneumonia.

Journal: Diagnostic microbiology and infectious disease 20050701

Title: Potency and spectrum of tigecycline tested against an international collection of bacterial pathogens associated with skin and soft tissue infections (2000-2004).

Journal: Diagnostic microbiology and infectious disease 20050701

Title: Antimicrobial activity of tigecycline tested against nosocomial bacterial pathogens from patients hospitalized in the intensive care unit.

Journal: Diagnostic microbiology and infectious disease 20050701

Title: Activity of tigecycline tested against a global collection of Enterobacteriaceae, including tetracycline-resistant isolates.

Journal: Diagnostic microbiology and infectious disease 20050701

Title: In vitro activity of tigecycline against 6792 Gram-negative and Gram-positive clinical isolates from the global Tigecycline Evaluation and Surveillance Trial (TEST Program, 2004).

Journal: Diagnostic microbiology and infectious disease 20050701

Title: Comparative evaluation of tigecycline and vancomycin, with and without rifampicin, in the treatment of methicillin-resistant Staphylococcus aureus experimental osteomyelitis in a rabbit model.

Journal: The Journal of antimicrobial chemotherapy 20050601

Title: Steady-state serum and intrapulmonary pharmacokinetics and pharmacodynamics of tigecycline.

Journal: International journal of antimicrobial agents 20050601

Title: In vitro activity of tigecycline against ampicillin-resistant Haemophilus influenzae isolates.

Journal: The Journal of antimicrobial chemotherapy 20050501

Title: Reproducibility assessment of tigecycline MIC results by broth microdilution methods using commercially prepared dry-form panels.

Journal: Diagnostic microbiology and infectious disease 20050501

Title: Antibacterial Drug Discovery and Development Summit - Tenth Annual SRI Summit.

Journal: IDrugs : the investigational drugs journal 20050501

Title: In vitro evaluation of tigecycline and comparative agents in 3049 clinical isolates: 2001 to 2002.

Journal: Diagnostic microbiology and infectious disease 20050401

Title: Tigecycline: clinical evidence and formulary positioning.

Journal: International journal of antimicrobial agents 20050301

Title: [Tigecycline: a new antibiotic in ongoing clinical development].

Journal: Medecine et maladies infectieuses 20050201

Title: Tigecycline: an investigational glycylcycline antimicrobial with activity against resistant gram-positive organisms.

Journal: Clinical therapeutics 20050101

Title: Tigecycline: a novel glycylcycline.

Journal: Drugs 20050101

Title: A multicenter trial of the efficacy and safety of tigecycline versus imipenem/cilastatin in patients with complicated intra-abdominal infections [Study ID Numbers: 3074A1-301-WW; ClinicalTrials.gov Identifier: NCT00081744].

Journal: BMC infectious diseases 20050101

Title: Tigecycline: a review of a new glycylcycline antibiotic.

Journal: The Journal of dermatological treatment 20050101

Title: New drugs: tigecycline, ziconotide, and clofarabine.

Journal: Journal of the American Pharmacists Association : JAPhA 20050101

Title: In vitro activities of tigecycline, ertapenem, isepamicin, and other antimicrobial agents against clinically isolated organisms in Taiwan.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20050101

Title: Tigecycline.

Journal: Drugs 20050101

Title: Antimicrobial activity of tigecycline (GAR-936) tested against 3498 recent isolates of Staphylococcus aureus recovered from nosocomial and community-acquired infections.

Journal: International journal of antimicrobial agents 20041201

Title: In vitro activities of tigecycline against clinical isolates from Shanghai, China.

Journal: Diagnostic microbiology and infectious disease 20041201

Title: Results of tigecycline trials announced.

Journal: The Lancet. Infectious diseases 20041201

Title: Recent advances in the treatment of infections due to resistant Staphylococcus aureus.

Journal: Current opinion in infectious diseases 20041201

Title: Quantitation of tigecycline, a novel glycylcycline [corrected] by liquid chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041125

Title: Clinical glycopeptide-intermediate staphylococci tested against arbekacin, daptomycin, and tigecycline.

Journal: Diagnostic microbiology and infectious disease 20041001

Title: In vitro activity of tigecycline (GAR-936) tested against 11,859 recent clinical isolates associated with community-acquired respiratory tract and gram-positive cutaneous infections.

Journal: Diagnostic microbiology and infectious disease 20040701

Title: Results of a multicenter, randomized, open-label efficacy and safety study of two doses of tigecycline for complicated skin and skin-structure infections in hospitalized patients.

Journal: Clinical therapeutics 20040501

Title: Comparison of tetracycline and tigecycline binding to ribosomes mapped by dimethylsulphate and drug-directed Fe2+ cleavage of 16S rRNA.

Journal: The Journal of antimicrobial chemotherapy 20040401

Title: The glycylcyclines: a comparative review with the tetracyclines.

Journal: Drugs 20040101

Title: Oritavancin and tigecycline: investigational antimicrobials for multidrug-resistant bacteria.

Journal: Pharmacotherapy 20040101

Title: In vitro activity of tigecycline (GAR-936), a novel glycylcycline, against vancomycin-resistant enterococci and staphylococci with diminished susceptibility to glycopeptides.

Journal: The Journal of antimicrobial chemotherapy 20030701

Title: [Other antimicrobial agents (linezolid, quinupristin/dalfopristin, glycylcycline etc)].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20030301

Title: Antimicrobial activity of tigecycline (GAR-936) against Enterococcus faecium and Staphylococcus aureus used alone and in combination.

Journal: Pharmacotherapy 20021201

Title: Comparative in vitro activities of tigecycline (GAR-936) and other antimicrobial agents against Stenotrophomonas maltophilia.

Journal: The Journal of antimicrobial chemotherapy 20021101

Title: Comparison of the in vitro activity of the glycylcycline tigecycline (formerly GAR-936) with those of tetracycline, minocycline, and doxycycline against isolates of nontuberculous mycobacteria.

Journal: Antimicrobial agents and chemotherapy 20021001

Title: Activity of GAR-936 and other antimicrobial agents against North American isolates of Staphylococcus aureus.

Journal: International journal of antimicrobial agents 20020901

Title: Antibiotic resistance among clinical isolates of Acinetobacter in the UK, and in vitro evaluation of tigecycline (GAR-936).

Journal: The Journal of antimicrobial chemotherapy 20020301

Title: In vitro activity of 11 antimicrobial agents, including gatifloxacin and GAR936, tested against clinical isolates of Mycobacterium marinum.

Journal: Diagnostic microbiology and infectious disease 20020201

Title: New developments in tetracycline antibiotics: glycylcyclines and tetracycline efflux pump inhibitors.

Journal: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20020101

Title: Quinolone, everninomycin, glycylcycline, carbapenem, lipopeptide and cephem antibacterials in clinical development.

Journal: Current medicinal chemistry 20011201

Title: In vitro antimicrobial activity of GAR-936 tested against antibiotic-resistant gram-positive blood stream infection isolates and strains producing extended-spectrum beta-lactamases.

Journal: Diagnostic microbiology and infectious disease 20010801

Title: GAR-936 (9-t-butylglycylamido-minocycline) susceptibility test development for streptococci, Haemophilus influenzae and Neisseria gonorrhoeae: preliminary guidelines and interpretive criteria.

Journal: International journal of antimicrobial agents 20010701

Title: Antimicrobial activity and spectrum of the new glycylcycline, GAR-936 tested against 1,203 recent clinical bacterial isolates.

Journal: Diagnostic microbiology and infectious disease 20000101

Title: Disk diffusion susceptibility test development for the new glycylcycline, GAR-936.

Journal: Diagnostic microbiology and infectious disease 19991101

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Tags:220620-09-7 Molecular Formula|220620-09-7 MDL|220620-09-7 SMILES|220620-09-7 Tigecycline