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1334714-66-7,MFCD31544362
Catalog No.:AA01EOPN

1334714-66-7 | Eravacycline dihydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
95%
in stock  
$1,319.00   $923.00
- +
10mg
≥96%
in stock  
$1,913.00   $1,339.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EOPN
Chemical Name:
Eravacycline dihydrochloride
CAS Number:
1334714-66-7
Molecular Formula:
C27H33Cl2FN4O8
Molecular Weight:
631.4773
MDL Number:
MFCD31544362
SMILES:
O=C(Nc1cc(F)c2c(c1O)C(=O)C1=C(O)[C@]3([C@@H](C[C@@H]1C2)[C@H](N(C)C)C(=C(C3=O)C(=O)N)O)O)CN1CCCC1.Cl.Cl
Properties
Computed Properties
 
Complexity:
1200  
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
42  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
8  
Rotatable Bond Count:
5  

Literature

Title: Seifert H, et al. In-vitro activity of the novel fluorocycline eravacycline against carbapenem non-susceptible Acinetobacter baumannii. Int J Antimicrob Agents. 2017 Jul 10.

Title: Zhao M, et al. In Vivo Pharmacodynamic Target Assessment of Eravacycline against Escherichia coli in a Murine Thigh Infection Model. Antimicrob Agents Chemother. 2017 Jun 27;61(7).

Title: Xiao XY, et al. Fluorocyclines: a potent, broad spectrum antibacterial agent. J Med Chem. 2012 Jan 26;55(2):597-605.

Title: Sutcliffe JA, et al. Antibacterial activity of eravacycline (TP-434), a novel fluorocycline, against hospital and community pathogens. Antimicrob Agents Chemother. 2013 Nov;57(11):5548-58.

Title: Grossman TH, et al. Eravacycline (TP-434) is efficacious in animal models of infection. Antimicrob Agents Chemother. 2015 May;59(5):2567-71.

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Tags:1334714-66-7 Molecular Formula|1334714-66-7 MDL|1334714-66-7 SMILES|1334714-66-7 Eravacycline dihydrochloride