Catalog No.:AA003UWU

23739-88-0 | Triacetyl-beta-cyclodextrin

Name: Name:Triacetyl-beta-cyclodextrin
Brand: AABLOCKS
SKU: AA003UWU
Availability: InStock
Rating: 90 (10 reviews)

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Purity

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Price(USD)

Quantity

97%

in stock

$75.00 $53.00

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97%

in stock

$127.00 $89.00

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25g

97%

in stock

$320.00 $224.00

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Technical Information
Properties
Downstream Synthesis Route
Literature
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Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA003UWU

Chemical Name:

Triacetyl-beta-cyclodextrin

CAS Number:

23739-88-0

MDL Number:

MFCD00074981

SMILES:

CC(=O)OC[C@H]1O[C@@H]2O[C@@H]3[C@@H](COC(=O)C)O[C@@H]([C@H]([C@@H]3OC(=O)C)OC(=O)C)O[C@@H]3[C@@H](COC(=O)C)O[C@@H]([C@H]([C@@H]3OC(=O)C)OC(=O)C)O[C@@H]3[C@@H](COC(=O)C)O[C@@H]([C@H]([C@@H]3OC(=O)C)OC(=O)C)O[C@@H]3[C@H](O[C@H](O[C@@H]4[C@H](O[C@H](O[C@@H]5[C@H](O[C@H](O[C@H]1[C@H]([C@@H]2OC(=O)C)OC(=O)C)[C@@H](OC(=O)C)[C@@H]5OC(=O)C)COC(=O)C)[C@@H](OC(=O)C)[C@@H]4OC(=O)C)COC(=O)C)[C@@H](OC(=O)C)[C@@H]3OC(=O)C)COC(=O)C |&1:0,2,4,5,7,9,10,12,14,15,17,19,25,26,31,37,39,45,46,51,57,59,65,66,71,77,79,85,90,95,100,110,115,125,130|

Properties

BP:

1361.8°C at 760 mmHg

Form:

Solid

MP:

204-206 °C(lit.)

Refractive Index:

123 ° (C=1, CH3CN)

Solubility:

Soluble in chloroform, DMF. Insoluble in water.

Storage:

-20 ℃;Inert atmosphere;

Computed Properties

Complexity:

3700

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Heavy Atom Count:

140

Hydrogen Bond Acceptor Count:

Rotatable Bond Count:

XLogP3:

-3

Downstream Synthesis Route

108-24-7

7585-39-9

23739-88-0

[1]Locationinpatent:experimentalpartIde,Yasuhiro;Hori,Yuji;Kobayashi,Soichi;Hossain,Md.Delwar;Kitamura,Tsugio[Synthesis,2010,#18,p.3083-3086]

[2]Locationinpatent:experimentalpartCh,Ratnasekhar;Tyagi,Mohit;Patil,PremanandRamrao;Kartha,K.P.Ravindranathan[TetrahedronLetters,2011,vol.52,#44,p.5841-5846]

[3]Lu,Kuo-Cheng;Hsieh,Shu-Yi;Patkar,LaxmikantN.;Chen,Chien-Tien;Lin,Chun-Cheng[Tetrahedron,2004,vol.60,#40,p.8967-8973]

[4]Locationinpatent:experimentalpartZhang,Jianbo;Zhang,Bo;Zhou,Jiafen;Li,Juan;Shi,Chunjuan;Huang,Ting;Wang,Zhongfu;Tang,Jie[JournalofCarbohydrateChemistry,2011,vol.30,#3,p.165-177]

[5]Locationinpatent:experimentalpartGrachev;Edunov;Kurochkina;Popkov;Levina;Nifant'Ev[RussianJournalofOrganicChemistry,2011,vol.47,#2,p.284-289]

[6]Chen,Chien-Tien;Kuo,Jen-Huang;Pawar,VijayD.;Munot,YogeshS.;Weng,Shieu-Shien;Ku,Cheng-Hsiu;Liu,Cheng-Yuan[JournalofOrganicChemistry,2005,vol.70,#4,p.1188-1197]

[7]Lian,Chang-Ming;Jiang,Li-Ping;Liu,Dong-Liang[ChineseChemicalLetters,2014,vol.25,#1,p.134-136]

[8]Jicsinszky,Laszlo;Martina,Katia;Caporaso,Marina;Cintas,Pedro;Zanichelli,Andrea;Cravotto,Giancarlo[PhysicalChemistryChemicalPhysics,2015,vol.17,#26,p.17380-17390]

[9]Hirayama;Yamanaka;Horikawa;Uekama[ChemicalandPharmaceuticalBulletin,1995,vol.43,#1,p.130-136]

[10]Tezuka;Hermawan[CarbohydrateResearch,1994,vol.260,#2,p.181-188]

[11]Uekama;Horikawa;Yamanaka;Hirayama[JournalofPharmacyandPharmacology,1994,vol.46,#9,p.714-717]

[12]Divakar,Soundar[IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,2003,vol.42,#5,p.1119-1122]

[13]Locationinpatent:experimentalpartInoue,Motoki;Hashizaki,Kaname;Taguchi,Hiroyuki;Saito,Yoshihiro[ChemicalandPharmaceuticalBulletin,2008,vol.56,#9,p.1335-1337]

530-78-9

23739-88-0

C14H10F3NO2*1.9C84H112O56

[1]MagneticResonanceinChemistry,2009,vol.47,p.133-141

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[1]MagneticResonanceinChemistry,2009,vol.47,p.133-141

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23739-88-0

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[1]JournalofPhysicsandChemistryofSolids,2010,vol.71,p.630-633

Literature

Title: Thermosensitive Pluronic hydrogel: prolonged injectable formulation for drug abuse.

Journal: Drug design, development and therapy 20100101

Title: Sustained-release matrix tablets of metformin hydrochloride in combination with triacetyl-beta-cyclodextrin.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080201

Title: Physical-chemical characterization of binary systems of metformin hydrochloride with triacetyl-beta-cyclodextrin.

Journal: Journal of pharmaceutical and biomedical analysis 20071105

Title: Multimodal molecular encapsulation of nicardipine hydrochloride by beta-cyclodextrin, hydroxypropyl-beta-cyclodextrin and triacetyl-beta-cyclodextrin in solution. Structural studies by 1H NMR and ROESY experiments.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030401

Title: Hydrophilic and hydrophobic cyclodextrins in a new sustained release oral formulation of nicardipine: in vitro evaluation and bioavailability studies in rabbits.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20030214

Title: Effect of the hydrophobic nature of triacetyl-beta-cyclodextrin on the complexation with nicardipine hydrochloride: physicochemical and dissolution properties of the kneaded and spray-dried complexes.

Journal: Chemical & pharmaceutical bulletin 20021201

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