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530-78-9,MFCD00002422
Catalog No.:AA003QIS

530-78-9 | Flufenamic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
98%
in stock  
$11.00   $8.00
- +
1g
98%
in stock  
$29.00   $20.00
- +
10g
≥98%
in stock  
$33.00   $23.00
- +
25g
>98.0%(T)(HPLC)
in stock  
$56.00   $40.00
- +
50g
≥98%
in stock  
$96.00   $67.00
- +
100g
≥98%
in stock  
$173.00   $121.00
- +
250g
≥98%
in stock  
$345.00   $241.00
- +
500g
>98.0%(T)(HPLC)
in stock  
$443.00   $310.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003QIS
Chemical Name:
Flufenamic acid
CAS Number:
530-78-9
Molecular Formula:
C14H10F3NO2
Molecular Weight:
281.2299
MDL Number:
MFCD00002422
SMILES:
OC(=O)c1ccccc1Nc1cccc(c1)C(F)(F)F
Properties
Properties
 
BP:
373.9°C at 760 mmHg  
Form:
Solid  
MP:
129-131°C  
Storage:
Light sensitive;Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
346  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
5.2  

Upstream Synthesis Route

[1]JournaloftheAmericanChemicalSociety,1960,vol.82,p.1600-1607

[1]BioorganicandMedicinalChemistryLetters,2011,vol.21,#5,p.1464-1468

[2]JournalofMedicinalChemistry,2012,vol.55,#5,p.2311-2323

[3]Patent:US9271961,2016,B2,.Locationinpatent:Page/Pagecolumn58;59

[4]Patent:US5462952,1995,A,

[1]TetrahedronLetters,1997,vol.38,#29,p.5107-5110

[2]SyntheticCommunications,1989,vol.19,#11-12,p.2077-2080

[3]JournaloftheAmericanChemicalSociety,1960,vol.82,p.1600-1607

[1]JournaloftheChemicalSociety,1948,p.32,33

[2]JournaloftheChemicalSociety,1946,p.116

[3]JournalofOrganicChemistry,2014,vol.79,#16,p.7451-7458

[1]BioorganicandMedicinalChemistryLetters,2011,vol.21,#5,p.1464-1468

[2]JournalofMedicinalChemistry,2012,vol.55,#5,p.2311-2323

[3]Patent:US9271961,2016,B2,

Downstream Synthesis Route

[1]Arzneimittel-Forschung/DrugResearch,1977,vol.27,p.1300-1312

[1]Arzneimittel-Forschung/DrugResearch,1977,vol.27,p.1300-1312

[1]Farmaco,EdizioneScientifica,1975,vol.30,p.276-286

[1]Farmaco,EdizioneScientifica,1975,vol.30,p.276-286

[1]Arzneimittel-Forschung/DrugResearch,1977,vol.27,p.1300-1312

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Journal: Journal of computational neuroscience 20091001

Title: Modulation of glutamate and glycine transporters by niflumic, flufenamic and mefenamic acids.

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Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090930

Title: Group I mGluR activation enhances Ca(2+)-dependent nonselective cation currents and rhythmic bursting in main olfactory bulb external tufted cells.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090923

Title: Involvement of an aldo-keto reductase (AKR1C3) in redox cycling of 9,10-phenanthrenequinone leading to apoptosis in human endothelial cells.

Journal: Chemico-biological interactions 20090914

Title: Evidence that TRPM7 is required for breast cancer cell proliferation.

Journal: American journal of physiology. Cell physiology 20090901

Title: Release of adenosine and ATP during ischemia and epilepsy.

Journal: Current neuropharmacology 20090901

Title: Gap junction inhibitors modulate S100B secretion in astrocyte cultures and acute hippocampal slices.

Journal: Journal of neuroscience research 20090815

Title: Interaction of endothelial cells with self-assembled monolayers for potential use in drug-eluting coronary stents.

Journal: Journal of biomedical materials research. Part B, Applied biomaterials 20090801

Title: Allergic and photoallergic contact dermartitis from etofenamate: study of 14 cases.

Journal: Contact dermatitis 20090801

Title: Requirement for the N-terminal coiled-coil domain for expression and function, but not subunit interaction of, the ADPR-activated TRPM2 channel.

Journal: The Journal of membrane biology 20090701

Title: Possible involvement of PPAR gamma in the regulation of basal channel opening of P2X7 receptor in cultured mouse astrocytes.

Journal: Life sciences 20090605

Title: Antimicrobial peptide-induced apoptotic death of leishmania results from calcium-de pend ent, caspase-independent mitochondrial toxicity.

Journal: The Journal of biological chemistry 20090605

Title: Pain Controlling and Cytokine-regulating Effects of Lyprinol, a Lipid Extract of Perna Canaliculus, in a Rat Adjuvant-induced Arthritis Model.

Journal: Evidence-based complementary and alternative medicine : eCAM 20090601

Title: The role of corneocytes in skin transport revised--a combined computational and experimental approach.

Journal: Pharmaceutical research 20090601

Title: Carbachol regulates pacemaker activities in cultured interstitial cells of Cajal from the mouse small intestine.

Journal: Molecules and cells 20090531

Title: Locomotor rhythm maintenance: electrical coupling among premotor excitatory interneurons in the brainstem and spinal cord of young Xenopus tadpoles.

Journal: The Journal of physiology 20090401

Title: Flufenamic acid is a tool for investigating TRPC6-mediated calcium signalling in human conditionally immortalised podocytes and HEK293 cells.

Journal: Cell calcium 20090401

Title: Induction of pacemaker currents by DA-9701, a prokinetic agent, in interstitial cells of Cajal from murine small intestine.

Journal: Molecules and cells 20090331

Title: AKR1C3 as a potential target for the inhibitory effect of dietary flavonoids.

Journal: Chemico-biological interactions 20090316

Title: Kisspeptin-10 facilitates a plasma membrane-driven calcium oscillator in gonadotropin-releasing hormone-1 neurons.

Journal: Endocrinology 20090301

Title: Ca2+-dependent induction of TRPM2 currents in hippocampal neurons.

Journal: The Journal of physiology 20090301

Title: Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux.

Journal: Journal of neurochemistry 20090301

Title: Zinc activates damage-sensing TRPA1 ion channels.

Journal: Nature chemical biology 20090301

Title: High-pressure NMR characterization of triacetyl-beta-cyclodextrin in supercritical carbon dioxide.

Journal: Magnetic resonance in chemistry : MRC 20090201

Title: Pharmacological characterization of pannexin-1 currents expressed in mammalian cells.

Journal: The Journal of pharmacology and experimental therapeutics 20090201

Title: Articular chondrocytes express connexin 43 hemichannels and P2 receptors - a putative mechanoreceptor complex involving the primary cilium?

Journal: Journal of anatomy 20090201

Title: Diacylglycerol analogues activate second messenger-operated calcium channels exhibiting TRPC-like properties in cortical neurons.

Journal: Journal of neurochemistry 20090101

Title: Feasibility of 19F-NMR for assessing the molecular mobility of flufenamic acid in solid dispersions.

Journal: Chemical & pharmaceutical bulletin 20090101

Title: Effect of organ culture on noradrenaline- evoked contraction, calcium signalling and TRPC expression in rat mesenteric artery.

Journal: Journal of vascular research 20090101

Title: The anti-inflammatory agent flufenamic acid depresses store-operated channels by altering mitochondrial calcium homeostasis.

Journal: Neuropharmacology 20090101

Title: The extracellular matrix controls gap junction protein expression and function in postnatal hippocampal neural progenitor cells.

Journal: BMC neuroscience 20090101

Title: Evaluation of the in vitro skin permeation of antiviral drugs from penciclovir 1% cream and acyclovir 5% cream used to treat herpes simplex virus infection.

Journal: BMC dermatology 20090101

Title: cAMP-dependent chloride conductance evokes ammonia-induced blebbing in the microglial cell line, BV-2.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101

Title: Novel transthyretin amyloid fibril formation inhibitors: synthesis, biological evaluation, and X-ray structural analysis.

Journal: PloS one 20090101

Title: Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia.

Journal: PloS one 20090101

Title: Lack of functional and expression homology between human and mouse aldo-keto reductase 1C enzymes: implications for modelling human cancers.

Journal: Molecular cancer 20090101

Title: Determination of diclofenac on a dysprosium nanowire- modified carbon paste electrode accomplished in a flow injection system by advanced filtering.

Journal: Sensors (Basel, Switzerland) 20090101

Title: Drug delivery from gold and titanium surfaces using self-assembled monolayers.

Journal: Biomaterials 20081201

Title: Dopamides, vanillylamides, ethanolamides, and arachidonic acid amides of anti-inflammatory and analgesic drug substances as TRPV1 ligands.

Journal: ChemMedChem 20081201

Title: Identification of pore residues engaged in determining divalent cationic permeation in transient receptor potential melastatin subtype channel 2.

Journal: The Journal of biological chemistry 20081010

Title: Validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of R-flurbiprofen using a single-isomer amino cyclodextrin derivative.

Journal: Journal of chromatography. A 20080919

Title: Kisspeptin excites gonadotropin-releasing hormone neurons through a phospholipase C/calcium-dependent pathway regulating multiple ion channels.

Journal: Endocrinology 20080901

Title: P2X7 receptor-Pannexin1 complex: pharmacology and signaling.

Journal: American journal of physiology. Cell physiology 20080901

Title: Charge compensation for NADPH oxidase activity in microglia in rat brain slices does not involve a proton current.

Journal: The European journal of neuroscience 20080901

Title: Determination of flurbiprofen enantiomers in plasma using a single-isomer amino cyclodextrin derivative in nonaqueous capillary electrophoresis.

Journal: Electrophoresis 20080901

Title: Further characterization of cation channels present in the chicken red blood cell membrane.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20080801

Title: Extrinsic fluorescent dyes as tools for protein characterization.

Journal: Pharmaceutical research 20080701

Title: Metabotropic receptor-activated calcium increases and store-operated calcium influx in mouse Müller cells.

Journal: Investigative ophthalmology & visual science 20080701

Title: Flufenamic acid affects multiple currents and causes intracellular Ca2+ release in Aplysia bag cell neurons.

Journal: Journal of neurophysiology 20080701

Title: Hypertonicity-induced cation channels rescue cells from staurosporine-elicited apoptosis.

Journal: Apoptosis : an international journal on programmed cell death 20080701

Title: Non-selective cation channel blockers: potential use in nervous system basic research and therapeutics.

Journal: Mini reviews in medicinal chemistry 20080701

Title: Intracellular Ca2+ store depletion induces the formation of macromolecular complexes involving hTRPC1, hTRPC6, the type II IP3 receptor and SERCA3 in human platelets.

Journal: Biochimica et biophysica acta 20080601

Title: Diverse properties of store-operated TRPC channels activated by protein kinase C in vascular myocytes.

Journal: The Journal of physiology 20080515

Title: ACh-induced depolarization in inner ear artery is generated by activation of a TRP-like non-selective cation conductance and inactivation of a potassium conductance.

Journal: Hearing research 20080501

Title: The use of reconstructed human epidermis for skin absorption testing: Results of the validation study.

Journal: Alternatives to laboratory animals : ATLA 20080501

Title: The physicochemical parameters of marker compounds and vehicles for use in in vitro percutaneous absorption studies.

Journal: Alternatives to laboratory animals : ATLA 20080501

Title: Kisspeptin depolarizes gonadotropin-releasing hormone neurons through activation of TRPC-like cationic channels.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080423

Title: Stimulated efflux of amino acids and glutathione from cultured hippocampal slices by omission of extracellular calcium: likely involvement of connexin hemichannels.

Journal: The Journal of biological chemistry 20080418

Title: Development and validation of a screening procedure for the assessment of inhibition using a recombinant enzyme.

Journal: Talanta 20080415

Title: ATP release by way of connexin 36 hemichannels mediates ischemic tolerance in vitro.

Journal: Biochemical and biophysical research communications 20080328

Title: H2O 2-stimulated Ca2+ influx via TRPM2 is not the sole determinant of subsequent cell death.

Journal: Pflugers Archiv : European journal of physiology 20080301

Title: Inhibition of the transient receptor potential cation channel TRPM2 by 2-aminoethoxydiphenyl borate (2-APB).

Journal: British journal of pharmacology 20080301

Title: catena-Poly[[bis-[2-(2,3-dimethyl-anilino)benzoato-κO]cadmium(II)]-di-μ-3-pyridylmethanol-κN:O;κO:N].

Journal: Acta crystallographica. Section E, Structure reports online 20080301

Title: Eupnea of in situ rats persists following blockers of in vitro pacemaker burster activities.

Journal: Respiratory physiology & neurobiology 20080227

Title: Conception of myeloperoxidase inhibitors derived from flufenamic acid by computational docking and structure modification.

Journal: Bioorganic & medicinal chemistry 20080215

Title: Simultaneous determination of aceclofenac and its three metabolites in plasma using liquid chromatography-tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20080213

Title: In-silico model of skin penetration based on experimentally determined input parameters. Part I: experimental determination of partition and diffusion coefficients.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080201

Title: Allergic contact dermatitis to etofenamate. Cross-reaction to other nonsteroidal anti-inflammatory drugs.

Journal: Contact dermatitis 20080201

Title: The protective effect of functional connexin43 channels on a human epithelial cell line exposed to oxidative stress.

Journal: Investigative ophthalmology & visual science 20080201

Title: Multivariate optimisation and validation of a capillary electrophoresis method for the analysis of resveratrol in a nutraceutical.

Journal: Talanta 20080115

Title: Constitutively active TRPC3 channels regulate basal ganglia output neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080109

Title: Angiotensin II-stimulated Ca2+ entry mechanisms in afferent arterioles: role of transient receptor potential canonical channels and reverse Na+/Ca2+ exchange.

Journal: American journal of physiology. Renal physiology 20080101

Title: What role do pacemakers play in the generation of respiratory rhythm?

Journal: Advances in experimental medicine and biology 20080101

Title: Contribution of pacemaker neurons to respiratory rhythms generation in vitro.

Journal: Advances in experimental medicine and biology 20080101

Title: Influence of human skin specimens consisting of different skin layers on the result of in vitro permeation experiments.

Journal: Skin pharmacology and physiology 20080101

Title: Chloride influx provokes lamellipodium formation in microglial cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

Title: A Role for the PPARgamma in Cancer Therapy.

Journal: PPAR research 20080101

Title: Role of peroxisome proliferator-activated receptor gamma and its ligands in the treatment of hematological malignancies.

Journal: PPAR research 20080101

Title: Peroxisome proliferator-activated receptors in the modulation of the immune/inflammatory response in atherosclerosis.

Journal: PPAR research 20080101

Title: Potential developmental neurotoxicity of pesticides used in Europe.

Journal: Environmental health : a global access science source 20080101

Title: Development of selective blockers for Ca²(+)-activated Cl channel using Xenopus laevis oocytes with an improved drug screening strategy.

Journal: Molecular brain 20080101

Title: Gap junction mediated intercellular metabolite transfer in the cochlea is compromised in connexin30 null mice.

Journal: PloS one 20080101

Title: Blockade of chloride channels suppresses engulfment of microspheres in the microglial cell line, BV-2.

Journal: Brain research 20071212

Title: Light-evoked calcium responses of isolated melanopsin-expressing retinal ganglion cells.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20071205

Title: Low-E probe for (19)F-(1)H NMR of dilute biological solids.

Journal: Journal of magnetic resonance (San Diego, Calif. : 1997) 20071201

Title: Perspectives on transdermal ultrasound mediated drug delivery.

Journal: International journal of nanomedicine 20071201

Title: Anti-inflammatory and immune therapy for Alzheimer's disease: current status and future directions.

Journal: Current neuropharmacology 20071201

Title: Thermodynamic properties of flufenamic and niflumic acids--specific and non-specific interactions in solution and in crystal lattices, mechanism of solvation, partitioning and distribution.

Journal: Journal of pharmaceutical and biomedical analysis 20071130

Title: Estimation of the transition temperature for an enantiotropic polymorphic system from the transformation kinetics monitored using Raman spectroscopy.

Journal: Journal of pharmaceutical and biomedical analysis 20071130

Title: New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose.

Journal: Neurochemical research 20071101

Title: Characteristics of biphasic slow depolarizing and slow hyperpolarizing potential in frog taste cell induced by parasympathetic efferent stimulation.

Journal: Chemical senses 20071101

Title: Store-operated calcium entry mediates intracellular alkalinization, ERK1/2, and Akt/PKB phosphorylation in bovine neutrophils.

Journal: Journal of leukocyte biology 20071101

Title: Calcium-dependent fast depolarizing afterpotentials in vasopressin neurons in the rat supraoptic nucleus.

Journal: Journal of neurophysiology 20071101

Title: Inhibition of the Na+/dicarboxylate cotransporter by anthranilic acid derivatives.

Journal: Molecular pharmacology 20071101

Title: Extracellular interconversion of nucleotides reveals an ecto-adenylate kinase activity in the rat hippocampus.

Journal: Neurochemical research 20071101

Title: Effects of ginseng total saponins on pacemaker currents of interstitial cells of Cajal from the small intestine of mice.

Journal: Biological & pharmaceutical bulletin 20071101

Title: Models for binding cooperativities of inhibitors with transthyretin.

Journal: Archives of biochemistry and biophysics 20071001

Title: Small-conductance Cl- channels contribute to volume regulation and phagocytosis in microglia.

Journal: The European journal of neuroscience 20071001

Title: Topical etofenamate to facilitate venipuncture.

Journal: Pediatric emergency care 20071001

Title: Inhibition of the myeloperoxidase chlorinating activity by non-steroidal anti-inflammatory drugs: flufenamic acid and its 5-chloro-derivative directly interact with a recombinant human myeloperoxidase to inhibit the synthesis of hypochlorous acid.

Journal: European journal of pharmacology 20070910

Title: Characterization of an oligomeric carbonyl reductase of dog liver: its identity with peroxisomal tetrameric carbonyl reductase.

Journal: Biological & pharmaceutical bulletin 20070901

Title: Are pacemaker properties required for respiratory rhythm generation in adult turtle brain stems in vitro?

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070801

Title: A novel inhibitor of hypertonicity-induced cation channels in HeLa cells.

Journal: The journal of physiological sciences : JPS 20070801

Title: Phosphatidylinositol 4,5-bisphosphate regulates inspiratory burst activity in the neonatal mouse preBötzinger complex.

Journal: The Journal of physiology 20070801

Title: Sex pheromone production in the silkworm, Bombyx mori, is mediated by store-operated Ca2+ channels.

Journal: Bioscience, biotechnology, and biochemistry 20070801

Title: Medullary pacemaker neurons are essential for both eupnea and gasping in mammals vs. medullary pacemaker neurons are essential for gasping, but not eupnea, in mammals.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20070801

Title: Medullary pacemaker neurons are essential for both eupnea and gasping in mammals vs. medullary pacemaker neurons are essential for gasping, but not eupnea, in mammals.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20070801

Title: Clinical studies with oral lipid based formulations of poorly soluble compounds.

Journal: Therapeutics and clinical risk management 20070801

Title: Flufenamic acid bi-directionally modulates the transient outward K(+) current in rat cerebellar granule cells.

Journal: The Journal of pharmacology and experimental therapeutics 20070701

Title: Inspiratory bursts in the preBötzinger complex depend on a calcium-activated non-specific cation current linked to glutamate receptors in neonatal mice.

Journal: The Journal of physiology 20070701

Title: A calcium-activated nonselective cation conductance underlies the plateau potential in rat substantia nigra GABAergic neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070613

Title: Basolateral Cl channels in primary airway epithelial cultures.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070601

Title: Eicosanoid biosynthesis inhibitors increase the susceptibility of Lymantria dispar to nucleopolyhedrovirus LdMNPV.

Journal: Journal of invertebrate pathology 20070601

Title: Non-steroidal anti-inflammatory drugs increase insulin release from beta cells by inhibiting ATP-sensitive potassium channels.

Journal: British journal of pharmacology 20070601

Title: Persistent sodium current in preBotzinger neurons is not necessary for respiratory rhythm generation in the neonatal mouse?

Journal: The Journal of physiology 20070601

Title: Postsynaptic mechanisms underlying responsiveness of amygdaloid neurons to cholecystokinin are mediated by a transient receptor potential-like current.

Journal: Molecular and cellular neurosciences 20070601

Title: Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy.

Journal: Chemical research in toxicology 20070601

Title: Glucuronidation of fenamates: kinetic studies using human kidney cortical microsomes and recombinant UDP-glucuronosyltransferase (UGT) 1A9 and 2B7.

Journal: Biochemical pharmacology 20070515

Title: First pharmacophore-based identification of androgen receptor down-regulating agents: discovery of potent anti-prostate cancer agents.

Journal: Bioorganic & medicinal chemistry 20070515

Title: Analysis of slow depolarizing potential in frog taste cell induced by parasympathetic efferent stimulation under hypoxia.

Journal: Chemical senses 20070501

Title: Endothelin-1 activates a Ca2+-permeable cation channel with TRPC3 and TRPC7 properties in rabbit coronary artery myocytes.

Journal: The Journal of physiology 20070501

Title: Functionalized magnetic nanoparticles for small-molecule isolation, identification, and quantification.

Journal: Analytical chemistry 20070501

Title: Effect of selected fluorinated drugs in a 'ringing' gel on rheological behaviour and skin permeation.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070401

Title: Mechanism of interaction of niflumic acid with heterologously expressed kidney CLC-K chloride channels.

Journal: The Journal of membrane biology 20070401

Title: Effects of riluzole and flufenamic acid on eupnea and gasping of neonatal mice in vivo.

Journal: Neuroscience letters 20070330

Title: Gap junction hemichannel-mediated release of glutathione from cultured rat astrocytes.

Journal: Neuroscience letters 20070319

Title: Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase.

Journal: The Journal of biological chemistry 20070316

Title: Activity-dependent initiation of a prolonged depolarization in aplysia bag cell neurons: role for a cation channel.

Journal: Journal of neurophysiology 20070301

Title: Multicommutated flow-through optosensors implemented with photochemically induced fluorescence: determination of flufenamic acid.

Journal: Analytical biochemistry 20070215

Title: TRPM4, a Ca2+-activated nonselective cation channel in mouse sino-atrial node cells.

Journal: Cardiovascular research 20070201

Title: Depolarization evoked by acetylcholine in mesenteric arteries of hypertensive rats attenuates endothelium-dependent hyperpolarizing factor.

Journal: Journal of hypertension 20070201

Title: Antagonist effect of flufenamic acid on TRPM2 cation channels activated by hydrogen peroxide.

Journal: Cell biochemistry and function 20070101

Title: Overlapping pharmacology of Ca2+-activated Cl- and K+ channels.

Journal: Trends in pharmacological sciences 20070101

Title: Inhibition of eryptosis and intraerythrocytic growth of Plasmodium falciparum by flufenamic acid.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20070101

Title: Aminocarbonyloxymethyl ester prodrugs of flufenamic acid and diclofenac: suppressing the rearrangement pathway in aqueous media.

Journal: Archiv der Pharmazie 20070101

Title: TRPM2.

Journal: Handbook of experimental pharmacology 20070101

Title: N-(p-amylcinnamoyl)anthranilic acid (ACA): a phospholipase A(2) inhibitor and TRP channel blocker.

Journal: Cardiovascular drug reviews 20070101

Title: Corticolimbic expression of TRPC4 and TRPC5 channels in the rodent brain.

Journal: PloS one 20070101

Title: Screening of gap junction antagonists on dye coupling in the rabbit retina.

Journal: Visual neuroscience 20070101

Title: [Etofenamate and the analgesic effect in the management of acute pain from spine in the emergency room].

Journal: Acta ortopedica mexicana 20070101

Title: [Ventricular extrasystole as manifestation of viral myocarditis and myopericarditis in young patients].

Journal: Terapevticheskii arkhiv 20070101

Title: The pK(a) Distribution of Drugs: Application to Drug Discovery.

Journal: Perspectives in medicinal chemistry 20070101

Title: Polymeric nanoparticles, nanospheres and nanocapsules, for cutaneous applications.

Journal: Drug target insights 20070101

Title: Angiotensin II activates two cation conductances with distinct TRPC1 and TRPC6 channel properties in rabbit mesenteric artery myocytes.

Journal: The Journal of physiology 20061201

Title: Diflunisal stabilizes familial amyloid polyneuropathy-associated transthyretin variant tetramers in serum against dissociation required for amyloidogenesis.

Journal: Neuroscience research 20061201

Title: Muscarinic control of graded persistent activity in lateral amygdala neurons.

Journal: The European journal of neuroscience 20061201

Title: Effects of flufenamic acid on fictive locomotion, plateau potentials, calcium channels and NMDA receptors in the lamprey spinal cord.

Journal: Neuropharmacology 20061101

Title: Non-steroidal anti-inflammatory drugs for heavy bleeding or pain associated with intrauterine-device use.

Journal: The Cochrane database of systematic reviews 20061018

Title: Additive-induced metastable single crystal of mefenamic acid.

Journal: Pharmaceutical research 20061001

Title: Functional expression of the TRPM4 cationic current in ventricular cardiomyocytes from spontaneously hypertensive rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20061001

Title: Comparison of bovine udder skin with human and porcine skin in percutaneous permeation experiments.

Journal: Alternatives to laboratory animals : ATLA 20061001

Title: Purine release from spinal cord microglia after elevation of calcium by glutamate.

Journal: Molecular pharmacology 20060901

Title: VEGF activates receptor-operated cation channels in human microvascular endothelial cells.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20060801

Title: A TRPC-like non-selective cation current activated by alpha 1-adrenoceptors in rat mesenteric artery smooth muscle cells.

Journal: Cell calcium 20060701

Title: Swelling-activated Cl- channels support Cl- secretion by bovine ciliary epithelium.

Journal: Investigative ophthalmology & visual science 20060601

Title: TEWL measurements as a routine method for evaluating the integrity of epidermis sheets in static Franz type diffusion cells in vitro. Limitations shown by transport data testing.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: The light-activated signaling pathway in SCN-projecting rat retinal ganglion cells.

Journal: The European journal of neuroscience 20060501

Title: Norepinephrine differentially modulates different types of respiratory pacemaker and nonpacemaker neurons.

Journal: Journal of neurophysiology 20060401

Title: Actions of glutamate and ivermectin on the pharyngeal muscle of Ascaridia galli: a comparative study with Caenorhabditis elegans.

Journal: International journal for parasitology 20060401

Title: Calcium antagonist isradipine-induced calcium influx through nonselective cation channels in human gingival fibroblasts.

Journal: European journal of medical research 20060327

Title: Gasping activity in vitro: a rhythm dependent on 5-HT2A receptors.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060308

Title: Bistable behavior originating in the axon of a crustacean motor neuron.

Journal: Journal of neurophysiology 20060301

Title: Neuronal chloride accumulation in olfactory epithelium of mice lacking NKCC1.

Journal: Journal of neurophysiology 20060301

Title: Tibolone metabolism in human liver is catalyzed by 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four isoforms of the aldo-keto reductase (AKR)1C subfamily.

Journal: The Journal of pharmacology and experimental therapeutics 20060301

Title: TRPC3 properties of a native constitutively active Ca2+-permeable cation channel in rabbit ear artery myocytes.

Journal: The Journal of physiology 20060301

Title: Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family.

Journal: Biological & pharmaceutical bulletin 20060301

Title: Second-order calibration of excitation-emission matrix fluorescence spectra for the determination of N-phenylanthranilic acid derivatives.

Journal: Applied spectroscopy 20060301

Title: A 'sample-and-hold' pulse-counting integrator as a mechanism for graded memory underlying sensorimotor adaptation.

Journal: Neuron 20060216

Title: P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060201

Title: Endogenous hemichannels play a role in the release of ATP from Xenopus oocytes.

Journal: Journal of cellular physiology 20060101

Title: Activation and inhibition of kidney CLC-K chloride channels by fenamates.

Journal: Molecular pharmacology 20060101

Title: Diversity of Cl(-) channels.

Journal: Cellular and molecular life sciences : CMLS 20060101

Title: Influence of nanoencapsulation on human skin transport of flufenamic acid.

Journal: Skin pharmacology and physiology 20060101

Title: Anti-inflammatory and immunosuppressive drugs and reproduction.

Journal: Arthritis research & therapy 20060101

Title: Calcium-sensing receptor stimulation induces nonselective cation channel activation in breast cancer cells.

Journal: The Journal of membrane biology 20060101

Title: Inhibition of hypertonicity-induced cation channels sensitizes HeLa cells to shrinkage-induced apoptosis.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101

Title: New potential anticancer agents based on the anthranilic acid scaffold: synthesis and evaluation of biological activity.

Journal: Journal of medicinal chemistry 20051229

Title: Fenamates and diltiazem modulate lipid-sensitive mechano-gated 2P domain K(+) channels.

Journal: Pflugers Archiv : European journal of physiology 20051201

Title: Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents.

Journal: Bioorganic & medicinal chemistry letters 20051201

Title: Effects of inhibitors of nonselective cation channels on the acetylcholine-induced depolarization of circular smooth muscle from the guinea-pig stomach antrum.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20051201

Title: Thiol-containing molecules interact with the myeloperoxidase/H2O2/chloride system to inhibit LDL oxidation.

Journal: Biochemical and biophysical research communications 20051111

Title: Partial mitochondrial inhibition causes striatal dopamine release suppression and medium spiny neuron depolarization via H2O2 elevation, not ATP depletion.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20051026

Title: Fluid secretion and the Na+-K+-2Cl- cotransporter in mouse exorbital lacrimal gland.

Journal: American journal of physiology. Cell physiology 20051001

Title: The role of TRPM channels in cell death.

Journal: Pflugers Archiv : European journal of physiology 20051001

Title: Small transthyretin (TTR) ligands as possible therapeutic agents in TTR amyloidoses.

Journal: Current drug targets. CNS and neurological disorders 20051001

Title: Inhibition study of rabbit liver cytosolic reductases involved in daunorubicin toxication.

Journal: Journal of enzyme inhibition and medicinal chemistry 20051001

Title: NMDA enhances a depolarization-activated inward current in subthalamic neurons.

Journal: Neuropharmacology 20050901

Title: Understanding solid-state reactions of organic crystals with density functional theory-based concepts.

Journal: The journal of physical chemistry. A 20050818

Title: Characterization of a proton-activated, outwardly rectifying anion channel.

Journal: The Journal of physiology 20050815

Title: The effects of flufenamic acid on spontaneous activity of smooth muscle tissue isolated from the guinea-pig stomach antrum.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20050801

Title: Gain modulation by serotonin in pyramidal neurones of the rat prefrontal cortex.

Journal: The Journal of physiology 20050715

Title: A quantitative model to evaluate solubility relationship of polymorphs from their thermal properties.

Journal: Pharmaceutical research 20050701

Title: Mechanisms of Na+ and Ca2+ influx into respiratory neurons during hypoxia.

Journal: Neuropharmacology 20050601

Title: Gap junction channels reconstituted in two closely apposed lipid bilayers.

Journal: Archives of biochemistry and biophysics 20050401

Title: UDP-glucuronosyltransferases and clinical drug-drug interactions.

Journal: Pharmacology & therapeutics 20050401

Title: ATP release through connexin hemichannels in corneal endothelial cells.

Journal: Investigative ophthalmology & visual science 20050401

Title: Blockade of chloride conductance antagonizes PMA-induced ramification in the murine microglial cell line, BV-2.

Journal: Brain research 20050328

Title: Comparison of four different in vitro systems to study the reservoir capacity of the stratum corneum.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20050302

Title: Comparison of functional properties of the Ca2+-activated cation channels TRPM4 and TRPM5 from mice.

Journal: Cell calcium 20050301

Title: Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes.

Journal: Journal of neurochemistry 20050301

Title: Dicumarol is a potent reversible inhibitor of gap junctional intercellular communication.

Journal: Archives of biochemistry and biophysics 20050215

Title: Cyclic nucleotide signaling mediates an odorant-suppressible chloride conductance in lobster olfactory receptor neurons.

Journal: Chemical senses 20050201

Title: Sodium and calcium current-mediated pacemaker neurons and respiratory rhythm generation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050112

Title: Development of nonsteroidal anti-inflammatory drug analogs and steroid carboxylates selective for human aldo-keto reductase isoforms: potential antineoplastic agents that work independently of cyclooxygenase isozymes.

Journal: Molecular pharmacology 20050101

Title: Novel properties of a mouse gamma-aminobutyric acid transporter (GAT4).

Journal: The Journal of membrane biology 20050101

Title: Application of stable isotope labeled glutathione and rapid scanning mass spectrometers in detecting and characterizing reactive metabolites.

Journal: Rapid communications in mass spectrometry : RCM 20050101

Title: Compounds exhibiting selective efficacy for different beta subunits of human recombinant gamma-aminobutyric acid A receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20041101

Title: Analysis of slow hyperpolarizing potentials in frog taste cells induced by glossopharyngeal nerve stimulation.

Journal: Chemical senses 20041001

Title: Voltage- and Ca2+-dependent burst generation in neuroendocrine Dahlgren cells in the teleost Platichthys flesus.

Journal: Journal of neuroendocrinology 20041001

Title: Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20041001

Title: Flufenamic acid is a pH-dependent antagonist of TRPM2 channels.

Journal: Neuropharmacology 20040901

Title: Synthesis of new 2-arylamino-6-trifluoromethylpyridine-3-carboxylic acid derivatives and investigation of their analgesic activity.

Journal: Bioorganic & medicinal chemistry 20040801

Title: Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy.

Journal: The Journal of general physiology 20040801

Title: Activation of a calcium-activated cation current during epileptiform discharges and its possible role in sustaining seizure-like events in neocortical slices.

Journal: Journal of neurophysiology 20040801

Title: Analysis of ketorolac and its related impurities by capillary electrochromatography.

Journal: Journal of chromatography. A 20040730

Title: Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity.

Journal: Bioorganic & medicinal chemistry letters 20040716

Title: Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative.

Journal: The Biochemical journal 20040715

Title: Substance P induces inward current and regulates pacemaker currents through tachykinin NK1 receptor in cultured interstitial cells of Cajal of murine small intestine.

Journal: European journal of pharmacology 20040708

Title: Differential contribution of pacemaker properties to the generation of respiratory rhythms during normoxia and hypoxia.

Journal: Neuron 20040708

Title: Functional characterization of a Ca(2+)-activated non-selective cation channel in human atrial cardiomyocytes.

Journal: The Journal of physiology 20040701

Title: Effects of various vehicles on the penetration of flufenamic acid into human skin.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20040701

Title: Inverse gene expression patterns for macrophage activating hepatotoxicants and peroxisome proliferators in rat liver.

Journal: Biochemical pharmacology 20040601

Title: Native state stabilization by NSAIDs inhibits transthyretin amyloidogenesis from the most common familial disease variants.

Journal: Laboratory investigation; a journal of technical methods and pathology 20040501

Title: Micellar electrokinetic chromatography for the simultaneous determination of ketorolac tromethamine and its impurities. Multivariate optimization and validation.

Journal: Journal of chromatography. A 20040402

Title: Enzymology of a carbonyl reduction clearance pathway for the HIV integrase inhibitor, S-1360: role of human liver cytosolic aldo-keto reductases.

Journal: Chemico-biological interactions 20040315

Title: Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action.

Journal: The Journal of biological chemistry 20040312

Title: Evidence of a role for TRPC channels in VEGF-mediated increased vascular permeability in vivo.

Journal: American journal of physiology. Heart and circulatory physiology 20040301

Title: Transient receptor potential-like channels mediate metabotropic glutamate receptor EPSCs in rat dopamine neurones.

Journal: The Journal of physiology 20040301

Title: Crystal structures of prostaglandin D(2) 11-ketoreductase (AKR1C3) in complex with the nonsteroidal anti-inflammatory drugs flufenamic acid and indomethacin.

Journal: Cancer research 20040301

Title: Calcium-dependent subthreshold oscillations determine bursting activity induced by N-methyl-D-aspartate in rat subthalamic neurons in vitro.

Journal: The European journal of neuroscience 20040301

Title: Mechanism of apoptosis induced by diazoxide, a K+ channel opener, in HepG2 human hepatoma cells.

Journal: Archives of pharmacal research 20040301

Title: Detergents profoundly affect inhibitor potencies against both cyclo-oxygenase isoforms.

Journal: The Biochemical journal 20040201

Title: Epigallocatechin-3-gallate increases intracellular [Ca2+] in U87 cells mainly by influx of extracellular Ca2+ and partly by release of intracellular stores.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040201

Title: Amyloidosis: a clinico-pathophysiological synopsis.

Journal: Seminars in cell & developmental biology 20040201

Title: Astrocytic connectivity in the hippocampus.

Journal: Neuron glia biology 20040201

Title: Topical NSAIDs for chronic musculoskeletal pain: systematic review and meta-analysis.

Journal: BMC musculoskeletal disorders 20040101

Title: Interactions of benzylpenicillin and non-steroidal anti-inflammatory drugs with the sodium-dependent dicarboxylate transporter NaDC-3.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20040101

Title: [Comparative clinical multicenter study to evaluate analgesic effectiveness of intramuscular etofenamate and diclofenac in patients with post-surgical pain].

Journal: Cirugia y cirujanos 20040101

Title: Diclofenac inhibition of sodium currents in rat dorsal root ganglion neurons.

Journal: Brain research 20031128

Title: Fundamental role of ClC-3 in volume-sensitive Cl- channel function and cell volume regulation in AGS cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20031101

Title: Pharmacological sensitivity of ATP release triggered by photoliberation of inositol-1,4,5-trisphosphate and zero extracellular calcium in brain endothelial cells.

Journal: Journal of cellular physiology 20031101

Title: In situ monitoring of wet granulation using online X-ray powder diffraction.

Journal: Pharmaceutical research 20031101

Title: Involvement of transient receptor potential-like channels in responses to mGluR-I activation in midbrain dopamine neurons.

Journal: The European journal of neuroscience 20031001

Title: Role of Ca2+-activated Cl- channels in the mechanism of apoptosis induced by cyclosporin A in a human hepatoma cell line.

Journal: Biochemical and biophysical research communications 20030919

Title: Fulfenamic acid sensitive, Ca(2+)-dependent inward current induced by nicotinic acetylcholine receptors in dopamine neurons.

Journal: Neuroscience research 20030801

Title: [Characterization of pacemaking currents in cultured interstitial cells of Cajal from mice small intestine].

Journal: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20030801

Title: Antimonial-induced increase in intracellular Ca2+ through non-selective cation channels in the host and the parasite is responsible for apoptosis of intracellular Leishmania donovani amastigotes.

Journal: The Journal of biological chemistry 20030704

Title: Ca(2+)- and voltage-dependent gating of Ca(2+)- and ATP-sensitive cationic channels in brain capillary endothelium.

Journal: Biophysical journal 20030701

Title: Non-steroidal anti-inflammatory drugs affect the methotrexate transport in IEC-6 cells.

Journal: Life sciences 20030613

Title: Comprehensive study of the luminescent properties and lifetimes of Eu(3+) and Tb(3+) chelated with various ligands in aqueous solutions: influence of the synergic agent, the surfactant and the energy level of the ligand triplet.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030601

Title: Closure of gap junction channels by arylaminobenzoates.

Journal: Molecular pharmacology 20030601

Title: Thiram and ziram stimulate non-selective cation channel and induce apoptosis in PC12 cells.

Journal: Neurotoxicology 20030601

Title: Calcium-activated cationic channel in rat sensory neurons.

Journal: The European journal of neuroscience 20030601

Title: Differential connexin expression, gap junction intercellular coupling, and hemichannel formation in NT2/D1 human neural progenitors and terminally differentiated hNT neurons.

Journal: Journal of neuroscience research 20030501

Title: Functional hemichannels in astrocytes: a novel mechanism of glutamate release.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030501

Title: A novel, voltage-dependent nonselective cation current activated by insulin in guinea pig isolated ventricular myocytes.

Journal: Circulation research 20030418

Title: TRPC5 as a candidate for the nonselective cation channel activated by muscarinic stimulation in murine stomach.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030401

Title: Low mortality rates related to respiratory virus infections after bone marrow transplantation.

Journal: Bone marrow transplantation 20030401

Title: The history of tocolysis.

Journal: BJOG : an international journal of obstetrics and gynaecology 20030401

Title: Inactivation of creatine kinase during the interaction of mefenamic acid with horseradish peroxidase and hydrogen peroxide: participation by the mefenamic acid radical.

Journal: Life sciences 20030314

Title: Selective and potent inhibitors of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) that metabolizes neurosteroids derived from progesterone.

Journal: Chemico-biological interactions 20030201

Title: Storage and release of ATP from astrocytes in culture.

Journal: The Journal of biological chemistry 20030110

Title: Effects of non-steroidal anti-inflammatory drugs on the methotrexate transport in rat small intestine.

Journal: Scandinavian journal of gastroenterology 20030101

Title: Allergic contact dermatitis from etofenamate without cross-sensitization to other anthranilic acid derivatives.

Journal: Dermatology (Basel, Switzerland) 20030101

Title: Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure produces good long term control of intraocular pressure without risk of sight threatening complications.

Journal: The British journal of ophthalmology 20021201

Title: Flufenamic acid blocks depolarizing afterpotentials and phasic firing in rat supraoptic neurones.

Journal: The Journal of physiology 20021201

Title: ATP release from human airway epithelial cells studied using a capillary cell culture system.

Journal: The Journal of physiology 20021115

Title: Structure-function relationship and role of tumor necrosis factor-alpha-converting enzyme in the down-regulation of L-selectin by non-steroidal anti-inflammatory drugs.

Journal: The Journal of biological chemistry 20021011

Title: Fenamate-induced enhancement of heterologously expressed HERG currents in Xenopus oocytes.

Journal: European journal of pharmacology 20021011

Title: Androgen receptors in prostate cancer.

Journal: Endocrine-related cancer 20020901

Title: Correlation between stratum corneum/water-partition coefficient and amounts of flufenamic acid penetrated into the stratum corneum.

Journal: Journal of pharmaceutical sciences 20020801

Title: Characterization of a Ca2+-activated nonselective cation channel during dedifferentiation of cultured rat ventricular cardiomyocytes.

Journal: The Journal of membrane biology 20020715

Title: A validated high-performance liquid chromatographic method for the determination of glibenclamide in human plasma and its application to pharmacokinetic studies.

Journal: Journal of pharmaceutical and biomedical analysis 20020515

Title: Chloride transport in rabbit esophageal epithelial cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20020401

Title: Effects of anion and cation inhibitors and carbonic anhydrase inhibitors upon the activity of the gypsy moth (Lepidoptera: Lymantriidae) nucleo-polyhedrovirus.

Journal: Journal of economic entomology 20020401

Title: Effects of flufenamic acid on smooth muscle of the carotid artery isolated from spontaneously hypertensive rats.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20020401

Title: Intercellular calcium signaling in astrocytes via ATP release through connexin hemichannels.

Journal: The Journal of biological chemistry 20020322

Title: Synthesis, stability and in vitro dermal evaluation of aminocarbonyloxymethyl esters as prodrugs of carboxylic acid agents.

Journal: Bioorganic & medicinal chemistry 20020301

Title: Human skin penetration of flufenamic acid: in vivo/in vitro correlation (deeper skin layers) for skin samples from the same subject.

Journal: The Journal of investigative dermatology 20020301

Title: TRPC6 is a candidate channel involved in receptor-stimulated cation currents in A7r5 smooth muscle cells.

Journal: American journal of physiology. Cell physiology 20020201

Title: A study of the conditions of the supercritical fluid extraction in the analysis of selected anti-inflammatory drugs in plasma.

Journal: Farmaco (Societa chimica italiana : 1989) 20020201

Title: Inhibition of gap junction hemichannels by chloride channel blockers.

Journal: The Journal of membrane biology 20020115

Title: Flufenamic acid: growth modulating effects on human aortic smooth muscle cells in vitro.

Journal: Journal of vascular and interventional radiology : JVIR 20020101

Title: An improved resazurin-based cytotoxicity assay for hepatic cells.

Journal: Cell biology and toxicology 20020101

Title: Non-selective cation channels and oxidative stress-induced cell swelling.

Journal: Biological research 20020101

Title: Renal papillary necrosis.

Journal: Toxicologic pathology 20020101

Title: P2X2 receptor mediates stimulation of parasensory cation absorption by cochlear outer sulcus cells and vestibular transitional cells.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20011201

Title: Combined contact and photocontact allergic dermatitis to etofenamate in flogoprofen gel.

Journal: American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20011201

Title: Comparative study of etofenamate and fentanyl for outpatient extracorporeal shockwave lithotripsy.

Journal: Scandinavian journal of urology and nephrology 20011201

Title: Potassium channel blocker activates extracellular signal-regulated kinases through Pyk2 and epidermal growth factor receptor in rat cardiomyocytes.

Journal: Journal of the American College of Cardiology 20011101

Title: Fenamates stimulate BKCa channel osteoblast-like MG-63 cells activity in the human.

Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20011101

Title: Selective inhibition of Cl(-) conductance in toad skin by blockers of Cl(-) channels and transporters.

Journal: American journal of physiology. Cell physiology 20011001

Title: A diacylglycerol-activated Ca2+ channel in PC12 cells (an adrenal chromaffin cell line) correlates with expression of the TRP-6 (transient receptor potential) protein.

Journal: The Biochemical journal 20010915

Title: Fenamates: a novel class of reversible gap junction blockers.

Journal: The Journal of pharmacology and experimental therapeutics 20010901

Title: Interrelation of permeation and penetration parameters obtained from in vitro experiments with human skin and skin equivalents.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20010810

Title: Calcium-sensitive nonselective cation channel identified in the epithelial cells isolated from the endolymphatic sac of guinea pigs.

Journal: The Journal of membrane biology 20010715

Title: Flufenamic acid enhances current through maxi-K channels in the trabecular meshwork of the eye.

Journal: Current eye research 20010601

Title: WY-14,643 and other agonists of the peroxisome proliferator-activated receptor reveal a new mode of action for salicylic acid in soybean disease resistance.

Journal: Planta 20010401

Title: The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor-activated Ca(2+)-permeable cation channel.

Journal: Circulation research 20010216

Title: Determination of diclofenac sodium, flufenamic acid, indomethacin and ketoprofen by LC-APCI-MS.

Journal: Journal of pharmaceutical and biomedical analysis 20010201

Title: Nonselective cation channels as effectors of free radical-induced rat liver cell necrosis.

Journal: Hepatology (Baltimore, Md.) 20010101

Title: Regulation of prostaglandin synthesis and cell adhesion by a tryptophan catabolizing enzyme.

Journal: BMC biochemistry 20010101

Title: Reconstructed skin equivalents for assessing percutaneous drug absorption from pharmaceutical formulations.

Journal: ALTEX 20010101

Title: Screening procedure for detection of non-steroidal anti-inflammatory drugs and their metabolites in urine as part of a systematic toxicological analysis procedure for acidic drugs and poisons by gas chromatography-mass spectrometry after extractive methylation.

Journal: Journal of analytical toxicology 20010101

Title: Etofenamate levels in human serum and synovial fluid following iontophoresis.

Journal: Arzneimittel-Forschung 20010101

Title: Effects of some pharmacological agents on the survival of unipedicled venous flaps: an experimental study.

Journal: Microsurgery 20010101

Title: Two opposing effects of non-steroidal anti-inflammatory drugs on the expression of the inducible cyclooxygenase. Mediation through different signaling pathways.

Journal: The Journal of biological chemistry 20000908

Title: A nonsteroidal anti-inflammatory drug, flufenamic acid, inhibits the expression of the androgen receptor in LNCaP cells.

Journal: Endocrinology 19991101

Title: Polycystin-L is a calcium-regulated cation channel permeable to calcium ions.

Journal: Nature 19990923

Title: Enhancement of low density lipoprotein catabolism by non-steroidal anti-inflammatory drugs in cultured HepG2 cells.

Journal: European journal of pharmacology 19990521

Title: [Levofloxacin-induced neurological adverse effects such as convulsion, involuntary movement (tremor, myoclonus and chorea like), visual hallucination in two elderly patients].

Journal: Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 19990301

Title: Identification of a principal mRNA species for human 3alpha-hydroxysteroid dehydrogenase isoform (AKR1C3) that exhibits high prostaglandin D2 11-ketoreductase activity.

Journal: Journal of biochemistry 19981101

Title: Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs.

Journal: The Journal of biological chemistry 19970207

Title: Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells.

Journal: The Biochemical journal 19960115

Title: Differential modulation of alpha 3 beta 2 and alpha 3 beta 4 neuronal nicotinic receptors expressed in Xenopus oocytes by flufenamic acid and niflumic acid.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19950301

Title: Positive regulation by chloride channel blockers of IsK channels expressed in Xenopus oocytes.

Journal: Molecular pharmacology 19941001

Title: Evidence for a role for the cyclic adenosine 3',5'-monophosphate/protein kinase-A pathway in regulation of the gonadotropin subunit messenger ribonucleic acids.

Journal: Endocrinology 19931101

Title: Voltage-dependent block of the cystic fibrosis transmembrane conductance regulator Cl- channel by two closely related arylaminobenzoates.

Journal: The Journal of general physiology 19930701

Title: Thyroid hormone uptake by hepatocytes: structure-activity relationships of phenylanthranilic acids with inhibitory activity.

Journal: Journal of medicinal chemistry 19930430

Title: Inhibition of aminoacid decarboxylases by non-steroidal antiinflammatory drugs.

Journal: International journal of tissue reactions 19840101

Title: [Ionized fluorine in the plasma and urine of subjects treated with organofluorine drugs prescribed in rheumatology].

Journal: Revue du rhumatisme et des maladies osteo-articulaires 19790201

Title: Letter: Aspirin sensitivity: other drugs.

Journal: Annals of internal medicine 19750201

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Title: Pongkorpsakol P, et al. Flufenamic acid protects against intestinal fluid secretion and barrier leakage in a mouse model of Vibrio cholerae infection through NF-κB inhibition and AMPK activation. Eur J Pharmacol. 2017 Mar 5;798:94-104.

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Tags:530-78-9 Molecular Formula|530-78-9 MDL|530-78-9 SMILES|530-78-9 Flufenamic acid