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Title: Antioxidant and hepatoprotective activities of Egyptian moraceous plants against carbon tetrachloride-induced oxidative stress and liver damage in rats.
Journal: Pharmaceutical biology 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: [Chemical constituents from Hydrangea paniculata].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101101
Title: A microfluidic approach for in vitro assessment of interorgan interactions in drug metabolism using intestinal and liver slices.
Journal: Lab on a chip 20101021
Title: Molecular cloning and characterization of a novel tomato xylosyltransferase specific for gentisic acid.
Journal: Journal of experimental botany 20101001
Title: 6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2.
Journal: Bioorganic & medicinal chemistry letters 20101001
Title: [Studies on the chemical constituents of Pharbitis purpurea].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20101001
Title: Development and application of UHPLC-MS/MS method for the determination of phenolic compounds in Chamomile flowers and Chamomile tea extracts.
Journal: Talanta 20100915
Title: Percutaneous absorption and metabolism of [14C]-ethoxycoumarin in a pig ear skin model.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100801
Title: Soybean metabolites regulated in root hairs in response to the symbiotic bacterium Bradyrhizobium japonicum.
Journal: Plant physiology 20100801
Title: Coumarins incorporating hydroxy- and chloro-moieties selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II.
Journal: Bioorganic & medicinal chemistry letters 20100801
Title: Magnetic activated release of umbelliferone from lipid matrices.
Journal: International journal of pharmaceutics 20100715
Title: LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis.
Journal: Plant physiology 20100701
Title: Antitermite activities of coumarin derivatives and scopoletin from Protium javanicum Burm. f.
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Title: Secondary metabolites and antimycobacterial activities from the roots of Ficus nervosa.
Journal: Chemistry & biodiversity 20100701
Title: catena-Poly[[[aqua(7-hydroxy-2H-1-benzopyran-2-one)sodium]-di-μ-aqua] 2-oxo-2H-1-benzopyran-7-olate monohydrate].
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Title: The metabolism and N-oxide reduction of olaquindox in liver preparations of rats, pigs and chicken.
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Title: [8-[Bis(carboxymethyl)aminomethyl]-6-bromo-7-hydroxycoumarin-4-yl]methyl moieties as photoremovable protecting groups for compounds with COOH, NH2, OH, and C=O functions.
Journal: The Journal of organic chemistry 20100507
Title: Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20100501
Title: Functional characterization of cytochrome P450 2A6 allelic variants CYP2A6*15, CYP2A6*16, CYP2A6*21, and CYP2A6*22.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20100501
Title: Structural determination of daphnecin, a new coumarinolignan from Daphne mucronata.
Journal: Journal of Asian natural products research 20100401
Title: Combined NMR and LC-MS analysis reveals the metabonomic changes in Salvia miltiorrhiza Bunge induced by water depletion.
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Title: Ethanol extract of Angelica gigas inhibits croton oil-induced inflammation by suppressing the cyclooxygenase - prostaglandin pathway.
Journal: Journal of veterinary science 20100301
Title: Fluorogenic substrates for the screening assay of transketolase through beta-elimination of umbelliferone--Development, scope and limitations.
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Title: Modulation of cytokine production by 7-hydroxycoumarin in vitro and its efficacy against influenza infection in mice.
Journal: Antiviral research 20100201
Title: Antinociceptive and anti-inflammatory properties of 7-hydroxycoumarin in experimental animal models: potential therapeutic for the control of inflammatory chronic pain.
Journal: The Journal of pharmacy and pharmacology 20100201
Title: Antioxidant activities of coumarins from Korean medicinal plants and their structure-activity relationships.
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Title: Effects of P-glycoprotein and Mrp2 inhibitors on the hepatobiliary disposition of Rhodamine 123 and its glucuronidated metabolite in isolated perfused rat livers.
Journal: Journal of pharmaceutical sciences 20100101
Title: Docking and 3D-QSAR studies of 7-hydroxycoumarin derivatives as CK2 inhibitors.
Journal: European journal of medicinal chemistry 20100101
Title: Characterization of a Chinese hamster ovary cell mutant having a mutation in elongation factor-2.
Journal: PloS one 20100101
Title: Up- and down-modulation of liver cytochrome P450 activities and associated events in two murine malaria models.
Journal: Malaria journal 20100101
Title: Randomized clinical trial of a phytotherapic compound containing Pimpinella anisum, Foeniculum vulgare, Sambucus nigra, and Cassia augustifolia for chronic constipation.
Journal: BMC complementary and alternative medicine 20100101
Title: Explaining the atypical reaction profiles of heme enzymes with a novel mechanistic hypothesis and kinetic treatment.
Journal: PloS one 20100101
Title: Analysis of quinapril by two solvent-saving methods: application of capillary column high-performance liquid chromatography with ultraviolet absorbance detection and LDI-TOF-MS.
Journal: Journal of AOAC International 20100101
Title: Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene.
Journal: BMC cancer 20100101
Title: 3D-QSAR and molecular docking studies on fused pyrazoles as p38α mitogen-activated protein kinase inhibitors.
Journal: International journal of molecular sciences 20100101
Title: Update on treatment of partial onset epilepsy: role of eslicarbazepine.
Journal: Neuropsychiatric disease and treatment 20100101
Title: Traditional herbal medicine in far-west Nepal: a pharmacological appraisal.
Journal: Journal of ethnobiology and ethnomedicine 20100101
Title: Small molecule immunosensing using surface plasmon resonance.
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Title: Anethum graveolens: An Indian traditional medicinal herb and spice.
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Title: Effect of pomegranate juice pre-treatment on the transport of carbamazepine across rat intestine.
Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101
Title: Effects of Angipars on oxidative inflammatory indices in a murine model of periodontitis.
Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101
Title: Formation of coumarines during the degradation of alkyl substituted aromatic oil components by the yeast Trichosporon asahii.
Journal: Applied microbiology and biotechnology 20091001
Title: A genetically encoded direct sensor of antibody-antigen interactions.
Journal: Chembiochem : a European journal of chemical biology 20090904
Title: Design and synthesis of coumarin-based Zn(2+) probes for ratiometric fluorescence imaging.
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Title: Antiviral activity of indole derivatives.
Journal: Antiviral research 20090801
Title: Yersinia enterocolitica targets cells of the innate and adaptive immune system by injection of Yops in a mouse infection model.
Journal: PLoS pathogens 20090801
Title: Novel coumarin and furan from the roots of Angelica pubescens f. biserrata.
Journal: Journal of Asian natural products research 20090801
Title: Total synthesis of (+)-angelmarin.
Journal: The Journal of organic chemistry 20090717
Title: Azo dyes decomposition on new nitrogen-modified anatase TiO2 with high adsorptivity.
Journal: Journal of hazardous materials 20090715
Title: Tyrosinase inhibitor activity of coumarin-resveratrol hybrids.
Journal: Molecules (Basel, Switzerland) 20090713
Title: Determination of osthol and its metabolites in a phase I reaction system and the Caco-2 cell model by HPLC-UV and LC-MS/MS.
Journal: Journal of pharmaceutical and biomedical analysis 20090712
Title: Probing the binding of 8-Acetyl-7-hydroxycoumarin to human serum albumin by spectroscopic methods and molecular modeling.
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090701
Title: The extent of phase I and phase II reactions is affected by the choice of enzyme used to prepare rat hepatocytes.
Journal: Chemico-biological interactions 20090515
Title: New 18-l process-scale counter-current chromatography centrifuge.
Journal: Journal of chromatography. A 20090508
Title: Highly enantioselective total synthesis of (-)-(3'S)-Lomatin and (+)-(3'S,4'R)-trans-khellactone.
Journal: Organic letters 20090507
Title: Antiamoebic coumarins from the root bark of Adina cordifolia and their new thiosemicarbazone derivatives.
Journal: European journal of medicinal chemistry 20090501
Title: Effects of umbelliferone in a murine model of allergic airway inflammation.
Journal: European journal of pharmacology 20090501
Title: [Coumarins from Peucedanum harry-smithii var. subglabrum].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090501
Title: A simple fluorescent probe for the determination of dissolved oxygen based on the catalytic activation of oxygen by iron(II) chelates.
Journal: Analytica chimica acta 20090427
Title: Evaluation of alternatives to warfarin as probes for Sudlow site I of human serum albumin: characterization by high-performance affinity chromatography.
Journal: Journal of chromatography. A 20090417
Title: Silkworm as a model animal to evaluate drug candidate toxicity and metabolism.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090401
Title: Umbelliferone aminoalkyl derivatives as inhibitors of human oxidosqualene-lanosterol cyclase.
Journal: Journal of enzyme inhibition and medicinal chemistry 20090401
Title: CYP2A6 genotypes and coumarin-oxidation phenotypes in a Thai population and their relationship to tobacco smoking.
Journal: European journal of clinical pharmacology 20090401
Title: Recombinant expression and functional characterisation of regiospecific flavonoid glucosyltransferases from Hieracium pilosella L.
Journal: Planta 20090401
Title: Discovery of novel Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase inhibitors.
Journal: Bioorganic & medicinal chemistry 20090315
Title: Effect of umbelliferone (7-hydroxycoumarin, 7-HOC) on the enzymatic, edematogenic and necrotic activities of secretory phospholipase A2 (sPLA2) isolated from Crotalus durissus collilineatus venom.
Journal: Toxicon : official journal of the International Society on Toxinology 20090315
Title: Synthesis of hydroxycoumarins and hydroxybenzo[f]- or [h]coumarins as lipid peroxidation inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20090215
Title: Kinetics of enzyme inhibition by active molluscicidal agents ferulic acid, umbelliferone, eugenol and limonene in the nervous tissue of snail Lymnaea acuminata.
Journal: Phytotherapy research : PTR 20090201
Title: Constitutive expression of bergaptol O-methyltransferase in Glehnia littoralis cell cultures.
Journal: Plant cell reports 20090201
Title: Determination of hydroxyl rate constants by a high-throughput fluorimetric assay: towards a unified reactivity scale for antioxidants.
Journal: The Analyst 20090201
Title: Metabolism of polybrominated diphenyl ethers (PBDEs) by human hepatocytes in vitro.
Journal: Environmental health perspectives 20090201
Title: Salicylic acid-induced changes to growth and phenolic metabolism in Matricaria chamomilla plants.
Journal: Plant cell reports 20090101
Title: Extraction of antioxidants from plants using ultrasonic methods and their antioxidant capacity.
Journal: Journal of separation science 20090101
Title: The effect of insecticide synergists on the response of scabies mites to pyrethroid acaricides.
Journal: PLoS neglected tropical diseases 20090101
Title: Further studies on the chemical constituents of Chinese folk medicine Gentiana apiata N.E. Br.
Journal: Journal of Asian natural products research 20090101
Title: Does the clock make the poison? Circadian variation in response to pesticides.
Journal: PloS one 20090101
Title: Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants.
Journal: BMC complementary and alternative medicine 20090101
Title: Negative ion electrospray ionization mass spectrometry and computational studies on substituted 7-hydroxycoumarins.
Journal: European journal of mass spectrometry (Chichester, England) 20090101
Title: Exploring the molecular basis of insecticide resistance in the dengue vector Aedes aegypti: a case study in Martinique Island (French West Indies).
Journal: BMC genomics 20090101
Title: Antioxidant Activity and Total Phenolic and Flavonoid Contents of Hieracium pilosella L. Extracts.
Journal: Sensors (Basel, Switzerland) 20090101
Title: Investigation of biosynthetic pathways to hydroxycoumarins during post-harvest physiological deterioration in Cassava roots by using stable isotope labelling.
Journal: Chembiochem : a European journal of chemical biology 20081215
Title: Differences in simulated liver concentrations of toxic coumarin metabolites in rats and different human populations evaluated through physiologically based biokinetic (PBBK) modeling.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20081201
Title: Umbelliferone and esculetin: inhibitors or substrates for polyphenol oxidases?
Journal: Biological & pharmaceutical bulletin 20081201
Title: Synthesis and free radical scavenging activity of some new spiropyranocoumarins.
Journal: Bioorganic & medicinal chemistry letters 20081101
Title: 7-hydroxycoumarin-hemicyanine hybrids: a new class of far-red emitting fluorogenic dyes.
Journal: Organic letters 20081002
Title: [Studies on chemical constituents from Elaeocarpus sylvestris].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20081001
Title: Protective effects of dietary chamomile tea on diabetic complications.
Journal: Journal of agricultural and food chemistry 20080910
Title: Synthesis and properties of umbelliferone-nitroxide radical hybrid compounds as fluorescence and spin-label probes.
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080901
Title: Studies of coumarins from the Chinese drug Qianhu, XXVII: structure of a new simple coumarin glycoside from Bai-Hua Qianhu, Peucedanum praeruptorum.
Journal: Chemical & pharmaceutical bulletin 20080901
Title: [Study on fluorescent properties of coumarin derivatives and determination of trace iron].
Journal: Guang pu xue yu guang pu fen xi = Guang pu 20080901
Title: Latent fluorophores based on a self-immolative linker strategy and suitable for protease sensing.
Journal: Bioconjugate chemistry 20080801
Title: Evaluation of natural substances from Evolvulus alsinoides L. with the purpose of determining their antioxidant potency.
Journal: Journal of enzyme inhibition and medicinal chemistry 20080801
Title: [Studies on chemical constituents of Peucedanum delavayi].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080801
Title: Multi-substrate flavonol O-glucosyltransferases from strawberry (Fragaria x ananassa) achene and receptacle.
Journal: Journal of experimental botany 20080701
Title: Analysis of ciprofloxacin by a simple high-performance liquid chromatography method.
Journal: Journal of chromatographic science 20080701
Title: A fluorescence-based assay for monoacylglycerol lipase compatible with inhibitor screening.
Journal: Assay and drug development technologies 20080601
Title: [Studies on chemical constituents of Saussurea laniceps].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080501
Title: [Study on steroids of Cacalia tangutica].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080501
Title: [Absorption and transport of 6 coumarins isolated from the roots of Angelica pubescens f. biserrata in human Caco-2 cell monolayer model].
Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080401
Title: Optimizing glycosyltransferase specificity via 'hot spot' saturation mutagenesis presents a catalyst for novobiocin glycorandomization.
Journal: Chemistry & biology 20080401
Title: [Studies on chemical constituents of the roots of Angelica pubescens].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080401
Title: Separation and identification of botanical insecticide 7-hydroxycoumarin and its biological activity against Aphis craccivora and Culex pipiens pallens.
Journal: Natural product research 20080310
Title: Activity of Mannich bases of 7-hydroxycoumarin against Flaviviridae.
Journal: Bioorganic & medicinal chemistry 20080301
Title: Artemisinin and CYP2A6 activity in healthy subjects.
Journal: European journal of clinical pharmacology 20080301
Title: Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships.
Journal: Journal of medicinal chemistry 20080227
Title: Rapid probing of photocatalytic activity on titania-based self-cleaning materials using 7-hydroxycoumarin fluorescent probe.
Journal: Analytica chimica acta 20080204
Title: Development of micromarkers with various photoluminescence colors as tracers for shadowing pursuits.
Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20080201
Title: Substrate arrays for fluorescence-based enzyme fingerprinting and high-throughput screening.
Journal: Annals of the New York Academy of Sciences 20080101
Title: Comparison of the effect of 4-hydroxycoumarin and umbelliferone on the phase transition of dipalmitoylphosphatidylcholine (DPPC) bilayers.
Journal: Pharmacological reports : PR 20080101
Title: TAC-scaffolded tripeptides as artificial hydrolytic receptors: a combinatorial approach toward esterase mimics.
Journal: Journal of combinatorial chemistry 20080101
Title: A review of coumarin derivatives in pharmacotherapy of breast cancer.
Journal: Current medicinal chemistry 20080101
Title: Biosynthetic origin of the 1-oxygen of umbelliferone in the root tissue of sweet potato.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101
Title: In vitro evaluation of hepatic and extra-hepatic metabolism of coumarins using rat subcellular fractions: correlation of in vitro clearance with in vivo data.
Journal: Drug metabolism and drug interactions 20080101
Title: A novel fluorogenic coumarin substrate for monitoring acid phosphatase activity at low pH environment.
Journal: Current chemical genomics 20080101
Title: [Chemical constituents from roots of Ferula sinkiangensis].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071101
Title: Synthesis and anti-inflammatory activity of 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans propenoic acid and its ester derivatives.
Journal: Bioorganic & medicinal chemistry letters 20071015
Title: Constituents, biological activities and quality control parameters of the crude extract and essential oil from Arracacia tolucensis var. multifida.
Journal: Journal of ethnopharmacology 20070815
Title: Rapid densitometric method for simultaneous analysis of umbelliferone, psoralen, and eugenol in herbal raw materials using HPTLC.
Journal: Journal of separation science 20070801
Title: Effect of umbelliferone on tail tendon collagen and haemostatic function in streptozotocin-diabetic rats.
Journal: Basic & clinical pharmacology & toxicology 20070801
Title: Antimicrobial activity of the methanolic extracts and compounds from Treculia obovoidea (Moraceae).
Journal: Journal of ethnopharmacology 20070725
Title: Protective effect of Umbelliferone on membranous fatty acid composition in streptozotocin-induced diabetic rats.
Journal: European journal of pharmacology 20070702
Title: Relationship between quantum-chemical descriptors of proton dissociation and experimental acidity constants of various hydroxylated coumarins. Identification of the biologically active species for xanthine oxidase inhibition.
Journal: European journal of medicinal chemistry 20070701
Title: Effect of chrysin and natural coumarins on UGT1A1 and 1A6 activities in rat and human hepatocytes in primary culture.
Journal: Planta medica 20070701
Title: Capillary electrochromatography of selected phenolic compounds of Chamomilla recutita.
Journal: Journal of chromatography. A 20070622
Title: The mitochondrial effects of novel apoptogenic molecules generated by psoralen photolysis as a crucial mechanism in PUVA therapy.
Journal: Blood 20070601
Title: Induction of phase I and II drug metabolism in rat small intestine and colon in vitro.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070601
Title: Artemisinin antimalarials moderately affect cytochrome P450 enzyme activity in healthy subjects.
Journal: Fundamental & clinical pharmacology 20070601
Title: Evaluation of the content and stability of the constituents of mother tinctures and tinctures: the case of Crataegus oxyacantha L. and Hieracium pilosella L.
Journal: Journal of pharmaceutical and biomedical analysis 20070509
Title: A review of the hepatotoxic plant Lantana camara.
Journal: Critical reviews in toxicology 20070501
Title: Determination of six bioactive components of Saussurea katochaete by capillary electrophoresis.
Journal: Biomedical chromatography : BMC 20070401
Title: Fluorogenic substrates for lipases, esterases, and acylases using a TIM-mechanism for signal release.
Journal: Biotechnology journal 20070201
Title: CYP2A6 polymorphisms: is there a role for pharmacogenomics in preventing coumarin-induced hepatotoxicity in lymphedema patients?
Journal: Pharmacogenomics 20070201
Title: Molecular cloning and functional characterization of psoralen synthase, the first committed monooxygenase of furanocoumarin biosynthesis.
Journal: The Journal of biological chemistry 20070105
Title: In silico prediction of pregnane X receptor activators by machine learning approaches.
Journal: Molecular pharmacology 20070101
Title: Enhanced resistance to Salmonella enterica serovar Typhimurium infection in mice after coumarin treatment.
Journal: Microbes and infection 20070101
Title: [Inhibitory effects of 11 coumarin compounds against growth of human bladder carcinoma cell line E-J in vitro].
Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20070101
Title: Antitumor and immunomodulatory effect of coumarin and 7-hydroxycoumarin against Sarcoma 180 in mice.
Journal: Journal of experimental therapeutics & oncology 20070101
Title: [Studies on the chemical constituents of the aerial parts of Seseli mairei].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070101
Title: Influence of umbelliferone on membrane-bound ATPases in streptozotocin-induced diabetic rats.
Journal: Pharmacological reports : PR 20070101
Title: Phytochemical and antinociceptive properties of Matayba elaeagnoides Radlk. barks.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101
Title: New Samarium(III), Gadolinium(III), and Dysprosium(III) Complexes of Coumarin-3-Carboxylic Acid as Antiproliferative Agents.
Journal: Metal-based drugs 20070101
Title: Influence of umbelliferone on glycoprotein components in diabetic rats.
Journal: Toxicology mechanisms and methods 20070101
Title: Tetrapleura tetraptera: molluscicidal activity and chemical constituents.
Journal: African journal of traditional, complementary, and alternative medicines : AJTCAM 20070101
Title: Inhibition of MMP-2 secretion from brain tumor cells suggests chemopreventive properties of a furanocoumarin glycoside and of chalcones isolated from the twigs of Dorstenia turbinata.
Journal: Phytochemistry 20061201
Title: In vivo evaluation of coumarin and nicotine as probe drugs to predict the metabolic capacity of CYP2A6 due to genetic polymorphism in Thais.
Journal: Drug metabolism and pharmacokinetics 20061201
Title: Monoamine oxidase inhibitory coumarins from the aerial parts of Dictamnus albus.
Journal: Archives of pharmacal research 20061201
Title: [Studies on chemical constituents from fruits of Paliurus ramosissimus].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061201
Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.
Journal: Journal of molecular graphics & modelling 20061101
Title: OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice.
Journal: PLoS medicine 20061101
Title: Simultaneous determination of urinary metabolites of methoxypsoralens in human and Umbelliferae medicines by high-performance liquid chromatography.
Journal: Journal of chromatographic science 20060901
Title: [Tissue-like cultures of rat hepatocytes in study of phase I and phase II drug metabolism].
Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20060901
Title: Chemical constituents of the root of Dystaenia takeshimana and their anti-inflammatory activity.
Journal: Archives of pharmacal research 20060801
Title: Selective effects of nitric oxide on the disposition of chlorzoxazone and dextromethorphan in isolated perfused rat livers.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701
Title: Interface of AOT/Brij mixed reverse micellar systems: conductometric and spectrophotometric investigations.
Journal: Journal of colloid and interface science 20060615
Title: Antioxidant role of Umbelliferone in STZ-diabetic rats.
Journal: Life sciences 20060613
Title: Molluscicidal activity of Ferula asafoetida, Syzygium aromaticum and Carum carvi and their active components against the snail Lymnaea acuminata.
Journal: Chemosphere 20060601
Title: Evaluation of laser speckle flowmetry for imaging cortical perfusion in experimental stroke studies: quantitation of perfusion and detection of peri-infarct depolarisations.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Empirical validation of a rat in vitro organ slice model as a tool for in vivo clearance prediction.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060401
Title: Relationships between chemical composition, physical properties and transfection efficiency of polysaccharide-spermine conjugates.
Journal: Biomaterials 20060301
Title: Accumulation of coumarins in Arabidopsis thaliana.
Journal: Phytochemistry 20060201
Title: Use of the land snail Helix aspersa as sentinel organism for monitoring ecotoxicologic effects of urban pollution: an integrated approach.
Journal: Environmental health perspectives 20060101
Title: [A new dicoumarin from stem bark of Wikstroemia indica].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060101
Title: Inter-species comparison of 7-hydroxycoumarin glucuronidation and sulfation in liver S9 fractions.
Journal: In vitro cellular & developmental biology. Animal 20060101
Title: Spectrofluorometric analysis of CYP2A6-catalyzed coumarin 7-hydroxylation.
Journal: Methods in molecular biology (Clifton, N.J.) 20060101
Title: Use of 7-ethoxycoumarin to monitor multiple enzymes in the human CYP1, CYP2, and CYP3 families.
Journal: Methods in molecular biology (Clifton, N.J.) 20060101
Title: Electrochemical profiles of Herba Saussureae Involucratae by capillary electrophoresis with electrochemical detection.
Journal: Phytochemical analysis : PCA 20060101
Title: Gitksan medicinal plants--cultural choice and efficacy.
Journal: Journal of ethnobiology and ethnomedicine 20060101
Title: Rapid analysis of coumarins using surface plasmon resonance.
Journal: Journal of AOAC International 20060101
Title: Chemical constituents of Selinum cryptotaenium.
Journal: Journal of Asian natural products research 20060101
Title: Ethnopharmacological evaluation of radal (leaves of Lomatia hirsuta) and isolation of 2-methoxyjuglone.
Journal: BMC complementary and alternative medicine 20060101
Title: Antihyperglycemic effect of umbelliferone in streptozotocin-diabetic rats.
Journal: Journal of medicinal food 20060101
Title: Synthesis, characterization, and cytotoxic activity of new lanthanum(III) complexes of bis-coumarins.
Journal: Bioinorganic chemistry and applications 20060101
Title: Structure-Activity Relationships of Synthetic Coumarins as HIV-1 Inhibitors.
Journal: Bioinorganic chemistry and applications 20060101
Title: A direct fluorometric assay for tissue transglutaminase.
Journal: Analytical biochemistry 20051215
Title: Generation and characterization of a transgenic mouse model with hepatic expression of human CYP2A6.
Journal: Biochemical and biophysical research communications 20051209
Title: Characterization of rat small intestinal and colon precision-cut slices as an in vitro system for drug metabolism and induction studies.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20051101
Title: Synthesis and antiinflammatory activity of coumarin derivatives.
Journal: Journal of medicinal chemistry 20051006
Title: New diorganotin(IV) derivatives of 7-hydroxycoumarin (umbelliferone) and their adducts with 1,10-phenanthroline.
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051001
Title: Activation of mitogen activated protein kinase pathways and melanogenesis by novel nitro-derivatives of 7-hydroxycomarin in human malignant melanoma cells.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050901
Title: An odorant-binding protein facilitates odorant transfer from air to hydrophilic surroundings in the blowfly.
Journal: Chemical senses 20050901
Title: Inhibition of P-glycoprotein transport function and reversion of MDR1 multidrug resistance by cnidiadin.
Journal: Cancer chemotherapy and pharmacology 20050801
Title: Effects of coumarin and 7OH-coumarin on bcl-2 and Bax expression in two human lung cancer cell lines in vitro.
Journal: Cell biology international 20050801
Title: Accumulation of biologically active furanocoumarins in agitated cultures of Ruta graveolens L. and Ruta graveolens ssp. divaricata (Tenore) Gams.
Journal: Die Pharmazie 20050801
Title: [Interaction between bovine serum albumin and umbelliferone with/without metal ions of Cu2+ or Zn2+].
Journal: Guang pu xue yu guang pu fen xi = Guang pu 20050801
Title: Antihyperlipidemic and antidiabetic effects of umbelliferone in streptozotocin diabetic rats.
Journal: The Yale journal of biology and medicine 20050701
Title: Rapid simultaneous determination of metabolic clearance of multiple compounds catalyzed in vitro by recombinant human UDP-glucuronosyltransferases.
Journal: Analytical biochemistry 20050601
Title: Sulfation in dog.
Journal: Current drug metabolism 20050601
Title: Post-stress metabolism involves umbelliferone production in anthocyanin-producing and nonproducing cells of Glehnia littoralis suspension cultures.
Journal: Journal of plant physiology 20050601
Title: Plant-derived anti-inflammatory compounds affect MIF tautomerase activity.
Journal: International immunopharmacology 20050501
Title: In vitro free radical and ONOO- scavengers from Sophora flavescens.
Journal: Archives of pharmacal research 20050501
Title: Effects of iron on Vitamin C/copper-induced hydroxyl radical generation in bicarbonate-rich water.
Journal: Free radical research 20050501
Title: Impact of umbelliferone on erythrocyte redox status in STZ-diabetic rats.
Journal: The Yale journal of biology and medicine 20050501
Title: Kinetic analysis of oxidation of coumarins by human cytochrome P450 2A6.
Journal: The Journal of biological chemistry 20050401
Title: Design and development of a fluorescent probe for monitoring hydrogen peroxide using photoinduced electron transfer.
Journal: Bioorganic & medicinal chemistry 20050215
Title: Lack of strain-related differences in drug metabolism and efflux transporter characteristics between CD-1 and athymic nude mice.
Journal: Cancer chemotherapy and pharmacology 20050201
Title: The influence of brain death on liver function.
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Title: Analysis of substrate specificities and tissue expression of rat UDP-glucuronosyltransferases UGT1A7 and UGT1A8.
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Title: A new technique for preparing precision-cut slices from small intestine and colon for drug biotransformation studies.
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Title: [Determination of scopoletin and umbelliferone contents in Saussurea medusa Maxim by high-performance liquid chromatography].
Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050101
Title: Troxerutin protects the isolated perfused rat liver from a possible lipid peroxidation by coumarin.
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Title: Accumulation of biologically active furanocoumarins in Ruta graveolens ssp. divaricata (Tenore) Gams in vitro culture.
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Title: Glucuronidation and sulfation of 7-hydroxycoumarin in liver matrices from human, dog, monkey, rat, and mouse.
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Title: Functional characterization of single nucleotide polymorphisms with amino acid substitution in CYP1A2, CYP2A6, and CYP2B6 found in the Japanese population.
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Title: Determination of CC-5013, an analogue of thalidomide, in human plasma by liquid chromatography-mass spectrometry.
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Title: Evidence for concurrent effects of exposure to environmental cadmium and lead on hepatic CYP2A6 phenotype and renal function biomarkers in nonsmokers.
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Title: A study of the role of cell cycle events mediating the action of coumarin derivatives in human malignant melanoma cells.
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Title: Pharmacokinetics of the nonsteroidal steroid sulphatase inhibitor 667 COUMATE and its sequestration into red blood cells in rats.
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Title: Novel squalene-hopene cyclase inhibitors derived from hydroxycoumarins and hydroxyacetophenones.
Journal: Chemical & pharmaceutical bulletin 20041001
Title: Glucosylation of phenolic compounds by Pharbitis nil hairy roots: I. Glucosylation of coumarin and flavone derivatives.
Journal: Bioscience, biotechnology, and biochemistry 20041001
Title: Umbelliferone released from hairy root cultures of Pharbitis nil treated with copper sulfate and its subsequent glucosylation.
Journal: Bioscience, biotechnology, and biochemistry 20040901
Title: Metabolic and structural viability of precision-cut rat lung slices in culture.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040801
Title: Identification of Val117 and Arg372 as critical amino acid residues for the activity difference between human CYP2A6 and CYP2A13 in coumarin 7-hydroxylation.
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Title: Effect of bisphenol A on drug metabolising enzymes in rat hepatic microsomes and precision-cut rat liver slices.
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Title: Validated assays for human cytochrome P450 activities.
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Title: Aldehyde detection by chromogenic/fluorogenic oxime bond fragmentation.
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Title: Structure-activity relationships of novel inhibitors of glyceraldehyde-3-phosphate dehydrogenase.
Journal: Bioorganic & medicinal chemistry letters 20040503
Title: Functional co-expression of xenobiotic metabolizing enzymes, rat cytochrome P450 1A1 and UDP-glucuronosyltransferase 1A6, in yeast microsomes.
Journal: Biochimica et biophysica acta 20040503
Title: An active and water-soluble truncation mutant of the human UDP-glucuronosyltransferase 1A9.
Journal: Molecular pharmacology 20040401
Title: Effects of chronic exposure to low-level cadmium on renal tubular function and CYP2A6-mediated coumarin metabolism in healthy human subjects.
Journal: Toxicology letters 20040321
Title: Investigation of intracellular signalling events mediating the mechanism of action of 7-hydroxycoumarin and 6-nitro-7-hdroxycoumarin in human renal cells.
Journal: Cancer letters 20040308
Title: Anthrone and oxanthrone C-glycosides from Picramnia latifolia collected in Peru.
Journal: Journal of natural products 20040301
Title: Apoptosis and cell cycle disturbances induced by coumarin and 7-hydroxycoumarin on human lung carcinoma cell lines.
Journal: Lung cancer (Amsterdam, Netherlands) 20040301
Title: [Isolation and structure identification of the chemical constituents from pine needles of Pinus massoniana Lamb].
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Title: Prediction of whole-body metabolic clearance of drugs through the combined use of slices from rat liver, lung, kidney, small intestine and colon.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040301
Title: Phase I and II enzyme characterization of two sources of HepG2 cell lines.
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Title: Phase I and phase II metabolic activities are retained in liver slices from mouse, rat, dog, monkey and human after cryopreservation.
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Title: Absolute stereochemistry of dihydrofuroangelicins bearing C-8 substituted double bonds: a combined chemical/exciton chirality protocol.
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Title: Studies on coumarins and coumarin-related compounds to determine their therapeutic role in the treatment of cancer.
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Title: Quantitative changes of secondary metabolites of Matricaria chamomilla by abiotic stress.
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Title: 'Open access' generic method for continuous determination of major human CYP450 probe substrates/metabolites and its application in drug metabolism studies.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20031201
Title: Modulation of mitogen-activated protein kinases by 6-nitro-7-hydroxycoumarin mediates apoptosis in renal carcinoma cells.
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Title: The first fluorogenic assay for detecting a Baeyer-Villigerase activity in microbial cells.
Journal: Organic & biomolecular chemistry 20031021
Title: Coumarins from Peucedanum wulongense.
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Title: Application of capillary electrophoresis with pH-mediated sample stacking to analysis of coumarin metabolites in microsomal incubations.
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Title: A low background high-throughput screening (HTS) fluorescence assay for lipases and esterases using acyloxymethylethers of umbelliferone.
Journal: Bioorganic & medicinal chemistry letters 20030707
Title: Interactions of a series of novel spiropyranocoumarin derivatives with reactive oxygen species.
Journal: The Journal of pharmacy and pharmacology 20030701
Title: Spectrofluorimetric analysis of 7-hydroxycoumarin binding to bovine phenol sulfotransferase.
Journal: Biochimica et biophysica acta 20030530
Title: Acaricidal activity of tonka bean extracts. Synthesis and structure-activity relationships of bioactive derivatives.
Journal: Journal of natural products 20030501
Title: Single copy of variant CYP2A6 alleles does not confer susceptibility to liver dysfunction in patients treated with coumarin.
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Title: Fluorogenic stereochemical probes for transaldolases.
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Title: Natural fungicides from Ruta graveolens L. leaves, including a new quinolone alkaloid.
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Title: Comparative metabolism and kinetics of coumarin in mice and rats.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030201
Title: Protection of coumarins against linoleic acid hydroperoxide-induced cytotoxicity.
Journal: Chemico-biological interactions 20030106
Title: Is neuroprotective efficacy of nNOS inhibitor 7-NI dependent on ischemic intracellular pH?
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Title: CYP2A13-catalysed coumarin metabolism: comparison with CYP2A5 and CYP2A6.
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Title: Superoxide organic chemistry within the liposomal bilayer, part II: a correlation between location and chemistry.
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Title: Variation in coumarin 7-hydroxylase activity associated with genetic polymorphism of cytochrome P450 2A6 and the body status of iron stores in adult Thai males and females.
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Title: Some coumarins and triphenylethene derivatives as inhibitors of human testes microsomal 17beta-hydroxysteroid dehydrogenase (17beta-HSD type 3): further studies with tamoxifen on the rat testes microsomal enzyme.
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Title: A novel ISFET-type biosensor based on P450 monooxygenases.
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Title: Characterization by liquid chromatography-nuclear magnetic resonance spectroscopy and liquid chromatography-mass spectrometry of two coupled oxidative-conjugative metabolic pathways for 7-ethoxycoumarin in human liver microsomes treated with alamethicin.
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Title: A rapid fluorescence-based assay for detecting soluble methane monooxygenase.
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Title: Inhibitory effects of phenylpropanoid metabolites on copper-induced protein oxidative modification of mice brain homogenate, in vitro.
Journal: Biological trace element research 20020201
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Title: Yu SM, et al. Umbelliferone exhibits anticancer activity via the induction of apoptosis and cell cycle arrest in HepG2 hepatocellular carcinoma cells. Mol Med Rep. 2015 Sep;12(3):3869-3873.
Umbelliferone, a versatile compound in organic synthesis, finds applications across various fields due to its unique properties and reactivity. It serves as a crucial building block in the creation of fluorescent probes utilized for the detection of cyanide anions in water under biological pH conditions. Additionally, it plays a significant role in the development of optical data storage materials, particularly in the synthesis of coumarin-based polymers. Umbelliferone's synthetic utility extends to the preparation of novobiocin derivatives, which exhibit antibacterial properties and serve as inhibitors of DNA gyrase, an essential enzyme in bacterial replication. Moreover, Umbelliferone serves as a valuable starting material for the synthesis of bioactive compounds such as (+)-decursinol and (+)-angelmarin. Its versatility and diverse applications make it an indispensable component in the synthesis of compounds with potential biological and pharmaceutical significance.
