Name: Name:Maduramicin Ammonium Salt
Brand: AABLOCKS
SKU: AA004W6R
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA004W6R

Chemical Name: Maduramicin Ammonium Salt

CAS Number: 84878-61-5

Molecular Formula: C47H83NO17

Molecular Weight: 934.1584

MDL Number: MFCD00865282

SMILES: CO[C@H]1C[C@H](O[C@H]([C@@H]1OC)C)O[C@H]1C[C@@H](OC1[C@]1(C)CCC(O1)[C@]1(C)CC[C@@]2(O1)C[C@H](O)[C@H]([C@H](O2)[C@H]([C@@H]1O[C@](O)(CC(=O)[O-])[C@H]([C@@H]([C@H]1OC)OC)C)C)C)C1O[C@](C)(O)[C@@H](C[C@@H]1C)C.[NH4+]

Properties

Form: Solid

MP: 170-175 °C

Storage: Inert atmosphere;2-8℃;

Complexity: 1610

Covalently-Bonded Unit Count: 2

Defined Atom Stereocenter Count: 24

Heavy Atom Count: 65

Hydrogen Bond Acceptor Count: 18

Hydrogen Bond Donor Count: 5

Rotatable Bond Count: 13

Literature fold

Title: Maduramicin induces apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20180801

Title: Transcriptome profile analysis reveals cardiotoxicity of maduramicin in primary chicken myocardial cells.

Journal: Archives of toxicology20180301

Title: Maduramicin-activated protein phosphatase 2A results in extracellular signal-regulated kinase 1/2 inhibition, leading to cytotoxicity in myocardial H9c2 cells.

Journal: Toxicology letters20180301

Title: Determination of narasin and monensin in bovine, swine, and chicken tissues by liquid chromatography with tandem mass spectrometry: first action 2011.24.

Journal: Journal of AOAC International20120101

Title: Rapid method for the simultaneous determination of six ionophores in feed by liquid chromatography/mass spectrometry.

Journal: Journal of AOAC International20120101

Title: Effects of ionophores on liver CYP1A and 3A in male broilers.

Journal: Journal of veterinary pharmacology and therapeutics20101201

Title: Validation of the procedure for the determination of maduramicin in concentrates, premixes, and feeds by liquid chromatography.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment20090101

Title: Eimeria tenella: analysis of differentially expressed genes in the monensin- and maduramicin-resistant lines using cDNA array.

Journal: Experimental parasitology20080601

Title: Efficacy of decoquinate against drug sensitive laboratory strains of Eimeria tenella and field isolates of Eimeria spp. in broiler chickens in China.

Journal: Veterinary parasitology20070720

Title: Isolation and selection of ionophore-tolerant Eimeria precocious lines: E. tenella, E. maxima and E. acervulina.

Journal: Veterinary parasitology20040206

Title: Determination of maduramicin in feedingstuffs and premixtures by liquid chromatography: development, validation, and interlaboratory study.

Journal: Journal of AOAC International20040101

Title: Study of resistance against some ionophores in Eimeria tenella field isolates.

Journal: Veterinary parasitology20011203

Title: In vitro anticryptosporidial activity of dinitroaniline herbicides.

Journal: FEMS microbiology letters19960301

Title: Evaluation of maduramicin and alborixin in a SCID mouse model of chronic cryptosporidiosis.

Journal: Antimicrobial agents and chemotherapy19950401

Title: Inhibition of Cryptosporidium parvum in neonatal Hsd:(ICR)BR Swiss miceby polyether ionophores and aromatic amidines.

Journal: Antimicrobial agents and chemotherapy19910701

Title: McDougald LR, et al. Efficacy of maduramicin ammonium against coccidiosis in turkeys under laboratory and floor-pen conditions.Avian Dis. 1990 Jul-Sep;34(3):634-8.

Title: Gao X, et al.Maduramicin induces apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways.Toxicol In Vitro. 2018 Aug;50:190-200.

84878-61-5 | Maduramicin Ammonium Salt