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28643-80-3,MFCD30377206
Catalog No.:AA002VW0

28643-80-3 | Nigericin Sodium

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥95%
in stock  
$82.00   $57.00
- +
10mg
≥95%
in stock  
$116.00   $81.00
- +
25mg
≥95%
in stock  
$253.00   $177.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002VW0
Chemical Name:
Nigericin Sodium
CAS Number:
28643-80-3
Molecular Formula:
C40H68O11
Molecular Weight:
724.9613
MDL Number:
MFCD30377206
SMILES:
COC1CC(CC2CCC(C(O2)C(C(=O)O)C)C)OC2(C1C)OC(CC2C)(C)C1CCC(O1)(C)C1OC(CC1C)C1OC(O)(CO)C(CC1C)C
Properties
Computed Properties
 
Complexity:
1240  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
19  
Heavy Atom Count:
52  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
9  

Literature

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: Yakisich JS, et al. Nigericin decreases the viability of multidrug-resistant cancer cells and lung tumorspheres and potentiates the effects of cardiac glycosides. Tumour Biol. 2017 Mar;39(3):1010428317694310

Title: Bissinger R, et al. Triggering of Suicidal Erythrocyte Death by the Antibiotic Ionophore Nigericin. Basic Clin Pharmacol Toxicol. 2016 May;118(5):381-9

Title: Deng CC, et al. Nigericin selectively targets cancer stem cells in nasopharyngeal carcinoma. Int J Biochem Cell Biol. 2013 Sep;45(9):1997-2006

Title: Zhou HM, et al. Suppression of colorectal cancer metastasis by nigericin through inhibition of epithelial-mesenchymal transition. World J Gastroenterol. 2012 Jun 7;18(21):2640-8

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SDS
Tags:28643-80-3 Molecular Formula|28643-80-3 MDL|28643-80-3 SMILES|28643-80-3 Nigericin Sodium