75330-75-5
[1]Clive;Murthy;Wee;Prasad;DaSilva;Majewski;Anderson;Evans;Haugen;Heerze;Barrie[JournaloftheAmericanChemicalSociety,1990,vol.112,#8,p.3018-3028]
[2]Clive,DerrickL.J.;Murthy,K.S.Keshava;Wee,AndrewG.H.;Prasad,J.Siva;Silva,GilV.J.da;etal.[JournaloftheAmericanChemicalSociety,1988,vol.110,#20,p.6914-6916]
[1]Sorensen,JohnL.;Auclair,Karine;Kennedy,Jonathan;Hutchinson,C.Richard;Vederas,JohnC.[OrganicandBiomolecularChemistry,2003,vol.1,#1,p.50-59]
[2]Ullrich,Thomas;Baumann,Karl;Welzenbach,Karl;Schmutz,Simone;Camenisch,Gian;Meingassner,JosefG.;Weitz-Schmidt,Gabriele[BioorganicandMedicinalChemistryLetters,2004,vol.14,#10,p.2483-2487]
[3]Bartmann,W.;Beck,G.;Granzer,E.;Jendralla,H.;Kerekjarto,B.v.;Wess,G.[TetrahedronLetters,1986,vol.27,#39,p.4709-4712]
[4]Locationinpatent:experimentalpartZhu,Lin;Yau,Lee-Fong;Lu,Jing-Guang;Zhu,Guo-Yuan;Wang,Jing-Rong;Han,Quan-Bin;Hsiao,Wen-Luan;Jiang,Zhi-Hong[JournalofAgriculturalandFoodChemistry,2012,vol.60,#4,p.934-939]
[1]Kuo,C.H.;Patchett,A.A.;Wendler,N.L.[JournalofOrganicChemistry,1983,vol.48,#12,p.1991-1998]
[1]Kuo,C.H.;Patchett,A.A.;Wendler,N.L.[JournalofOrganicChemistry,1983,vol.48,#12,p.1991-1998]
[2]Kuo,C.H.;Patchett,A.A.;Wendler,N.L.[JournalofOrganicChemistry,1983,vol.48,#12,p.1991-1998]
[1]Kuo,C.H.;Patchett,A.A.;Wendler,N.L.[JournalofOrganicChemistry,1983,vol.48,#12,p.1991-1998]
Title: Ganoderic Acid A improves high fat diet-induced obesity, lipid accumulation and insulin sensitivity through regulating SREBP pathway.
Journal: Chemico-biological interactions 20180625
Title: Anti-inflammatory effect of lovastatin is mediated via the modulation of NF-κB and inhibition of HDAC1 and the PI3K/Akt/mTOR pathway in RAW264.7 macrophages.
Journal: International journal of molecular medicine 20180201
Title: Rac1-mediated cardiac damage causes diastolic dysfunction in a mouse model of subacute doxorubicin-induced cardiotoxicity.
Journal: Archives of toxicology 20180101
Title: Curcumin rescues high fat diet-induced obesity and insulin sensitivity in mice through regulating SREBP pathway.
Journal: Toxicology and applied pharmacology 20160801
Title: Lovastatin lactone elicits human lung cancer cell apoptosis via a COX-2/PPARγ-dependent pathway.
Journal: Oncotarget 20160301
Title: Lovastatin prevents cisplatin-induced activation of pro-apoptotic DNA damage response (DDR) of renal tubular epithelial cells.
Journal: Toxicology and applied pharmacology 20160201
Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.
Journal: Chemical research in toxicology 20150518
Title: Efficacy of lovastatin on learning and memory deficits caused by chronic intermittent hypoxia-hypercapnia: through regulation of NR2B-containing NMDA receptor-ERK pathway.
Journal: PloS one 20140101
Title: Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines.
Journal: Journal of biomedical science 20140101
Title: Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action.
Journal: PloS one 20140101
Title: Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131201
Title: A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131101
Title: Hexavalent chromium-induced alteration of proteomic landscape in human skin fibroblast cells.
Journal: Journal of proteome research 20130705
Title: ATP-dependent transport of statins by human and rat MRP2/Mrp2.
Journal: Toxicology and applied pharmacology 20130601
Title: Dietary Monascus adlay supplements facilitate suppression of cigarette smoke-induced pulmonary endoplasmic reticulum stress, autophagy, apoptosis and emphysema-related PLGF in the rat.
Journal: Food chemistry 20130115
Title: Statin use and the risk of Clostridium difficile in academic medical centres.
Journal: Gut 20121101
Title: What is a food and what is a medicinal product in the European Union? Use of the benchmark dose (BMD) methodology to define a threshold for 'pharmacological action'.
Journal: Regulatory toxicology and pharmacology : RTP 20121101
Title: Bi-lateral changes to hippocampal cholesterol levels during epileptogenesis and in chronic epilepsy following focal-onset status epilepticus in mice.
Journal: Brain research 20121022
Title: [Histological character of intimal hyperplasia post jugular vein grafts and the protective effect of lovastatin].
Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20121018
Title: Anti-cancer characteristics of mevinolin against three different solid tumor cell lines was not solely p53-dependent.
Journal: Journal of enzyme inhibition and medicinal chemistry 20121001
Title: Development and validation of a simple and fast HPLC method for determination of lovastatin, pravastatin and simvastatin.
Journal: Journal of chromatographic science 20121001
Title: Combined blockade of signalling pathways shows marked anti-tumour potential in phaeochromocytoma cell lines.
Journal: Journal of molecular endocrinology 20121001
Title: Lovastatin-induced apoptosis is modulated by geranylgeraniol in a neuroblastoma cell line.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20121001
Title: Teratogenic risk of statins in pregnancy.
Journal: The Annals of pharmacotherapy 20121001
Title: HMG CoA reductase inhibitors, NSAIDs and risk of glioma.
Journal: International journal of cancer 20120915
Title: Novel properties of statins: suppression of the systemic and bone marrow responses induced by exposure to ambient particulate matter (PM(10)) air pollution.
Journal: American journal of physiology. Lung cellular and molecular physiology 20120915
Title: Red mold dioscorea: a potentially safe traditional function food for the treatment of hyperlipidemia.
Journal: Food chemistry 20120915
Title: Simvastatin evokes an unpredicted inhibition of β-adrenoceptor-mediated vasodilatation in porcine coronary artery.
Journal: European journal of pharmacology 20120905
Title: Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.
Journal: Oncology reports 20120901
Title: Interference with RhoA-ROCK signaling mechanism in autoreactive CD4+ T cells enhances the bioavailability of 1,25-dihydroxyvitamin D3 in experimental autoimmune encephalomyelitis.
Journal: The American journal of pathology 20120901
Title: A statin-regulated microRNA represses human c-Myc expression and function.
Journal: EMBO molecular medicine 20120901
Title: Statins and new-onset diabetes: a retrospective longitudinal cohort study.
Journal: Clinical therapeutics 20120901
Title: Statins increase cytochrome P450 4F3-mediated eicosanoids production in human liver cells: a PXR dependent mechanism.
Journal: Biochemical pharmacology 20120815
Title: Transforming growth factor-β2 induces synthesis and secretion of endothelin-1 in human trabecular meshwork cells.
Journal: Investigative ophthalmology & visual science 20120807
Title: Prenylation of Rho G-proteins: a novel mechanism regulating gene expression and protein stability in human trabecular meshwork cells.
Journal: Molecular neurobiology 20120801
Title: Statin medication in patients treated with antiepileptic drugs in Norway.
Journal: Pharmacoepidemiology and drug safety 20120801
Title: Cholesterol-lowering drugs inhibit lectin-like oxidized low-density lipoprotein-1 receptor function by membrane raft disruption.
Journal: Molecular pharmacology 20120801
Title: Short-term high-dose effect of lovastatin on thrombolysis by rt-PA in a human whole-blood in vitro clot model.
Journal: Current neurovascular research 20120801
Title: Statins and downstream inhibitors of the isoprenylation pathway increase type 2 iodothyronine deiodinase activity.
Journal: Endocrinology 20120801
Title: Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent.
Journal: PLoS biology 20120801
Title: Development of monacolin K-enriched ganghwayakssuk (Artemisia princeps Pamp.) by fermentation with Monascus pilosus.
Journal: Journal of microbiology and biotechnology 20120701
Title: Lovastatin protects mithochondrial and renal function in kidney ischemia-reperfusion in rats.
Journal: Acta cirurgica brasileira 20120701
Title: Protective effects of gypenosides against fatty liver disease induced by high fat and cholesterol diet and alcohol in rats.
Journal: Archives of pharmacal research 20120701
Title: [Effects of three different treatments on atherosclerosis and adipose in rats].
Journal: Zhonghua yi xue za zhi 20120619
Title: Cost-effectiveness of extended-release niacin/laropiprant added to a stable simvastatin dose in secondary prevention patients not at cholesterol goal in Germany.
Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20120601
Title: Impact of CYP2D6 polymorphisms on the pharmacokinetics of lovastatin in Chinese subjects.
Journal: European journal of clinical pharmacology 20120601
Title: Molecular pathways regulating macrophage polarization: implications for atherosclerosis.
Journal: Current atherosclerosis reports 20120601
Title: Lovastatin alters TGF-β-induced epithelial-mesenchymal transition in porcine lens epithelial cells.
Journal: Current eye research 20120601
Title: The natural carotenoid astaxanthin, a PPAR-α agonist and PPAR-γ antagonist, reduces hepatic lipid accumulation by rewiring the transcriptome in lipid-loaded hepatocytes.
Journal: Molecular nutrition & food research 20120601
Title: Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Journal: Journal of medicinal chemistry 20120524
Title: The lipid lowering drug lovastatin protects against doxorubicin-induced hepatotoxicity.
Journal: Toxicology and applied pharmacology 20120515
Title: Discovery of a new role of human resistin in hepatocyte low-density lipoprotein receptor suppression mediated in part by proprotein convertase subtilisin/kexin type 9.
Journal: Journal of the American College of Cardiology 20120508
Title: Effects of rose hip intake on risk markers of type 2 diabetes and cardiovascular disease: a randomized, double-blind, cross-over investigation in obese persons.
Journal: European journal of clinical nutrition 20120501
Title: Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120501
Title: Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120501
Title: Effects of a nutraceutical combination on left ventricular remodeling and vasoreactivity in subjects with the metabolic syndrome.
Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20120501
Title: Fibroblasts--a key host cell type in tumor initiation, progression, and metastasis.
Journal: Upsala journal of medical sciences 20120501
Title: Drug-drug interactions with glucagon-like peptide-1 receptor agonists.
Journal: The Annals of pharmacotherapy 20120501
Title: Assaying embryotoxicity in the test tube: current limitations of the embryonic stem cell test (EST) challenging its applicability domain.
Journal: Critical reviews in toxicology 20120501
Title: Prediction of drug-target interactions and drug repositioning via network-based inference.
Journal: PLoS computational biology 20120501
Title: Lovastatin regulates brain spontaneous low-frequency brain activity in neurofibromatosis type 1.
Journal: Neuroscience letters 20120425
Title: Molecular cloning of mevalonate pathway genes from Taraxacum brevicorniculatum and functional characterisation of the key enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Journal: Molecular biology reports 20120401
Title: Simultaneous determination of simvastatin, lovastatin and niacin in human plasma by LC-MS/MS and its application to a human pharmacokinetic study.
Journal: Biomedical chromatography : BMC 20120401
Title: Uniform mesoporous carbon as a carrier for poorly water soluble drug and its cytotoxicity study.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120401
Title: Complete mitochondrial genome of compactin-producing fungus Penicillium solitum and comparative analysis of Trichocomaceae mitochondrial genomes.
Journal: FEMS microbiology letters 20120401
Title: The molecular basis of chemoradiosensitivity in rectal cancer: implications for personalized therapies.
Journal: Langenbeck's archives of surgery 20120401
Title: Effect of lovastatin therapy and withdrawal on serum uric acid level in people with type 2 diabetic nephropathy.
Journal: Nucleosides, nucleotides & nucleic acids 20120401
Title: The Effects of Combined Treatment with an HMG-CoA Reductase Inhibitor and PPARγ Agonist on the Activation of Rat Pancreatic Stellate Cells.
Journal: Gut and liver 20120401
Title: Spectrofluorimetric determination of aliskiren in tablets and spiked human plasma through derivatization with dansyl chloride.
Journal: Journal of fluorescence 20120301
Title: In vitro evaluation of phototoxic properties of proton pump inhibitors, H2-receptor antagonists and statins.
Journal: Acta dermato-venereologica 20120301
Title: Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting.
Journal: Acta neuropathologica 20120301
Title: Differential blood lipid-lowering effects of alkylsulfonated chitosan of different molecular weights in Syrian hamsters in vivo.
Journal: Molecular medicine reports 20120301
Title: Hypolipidemic effects of kaempferide-7-O-(4''-O-acetylrhamnosyl)-3-O-rutinoside in hyperlipidemic rats induced by a high-fat diet.
Journal: Molecular medicine reports 20120301
Title: Towards safer and more predictable drug treatment--reflections from studies of the First BCPT Prize awardee.
Journal: Basic & clinical pharmacology & toxicology 20120301
Title: Medication prescribing patterns among chronic kidney disease patients in a hospital in Malaysia.
Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20120301
Title: Genomic analysis of the hydrocarbon-producing, cellulolytic, endophytic fungus Ascocoryne sarcoides.
Journal: PLoS genetics 20120301
Title: Anti-hypercholesterolemic and anti-atherosclerotic effects of polarized-light therapy in rabbits fed a high-cholesterol diet.
Journal: Laboratory animal research 20120301
Title: Antihypercholesterolaemic influence of dietary tender cluster beans (Cyamopsis tetragonoloba) in cholesterol fed rats.
Journal: The Indian journal of medical research 20120301
Title: Simvastatin inhibits sphingosylphosphorylcholine-induced differentiation of human mesenchymal stem cells into smooth muscle cells.
Journal: Experimental & molecular medicine 20120227
Title: Effects of 4-week administration of simvastatin in different doses on heart rate and blood pressure after metoprolol injection in normocholesterolaemic and normotensive rats.
Journal: Archives of medical science : AMS 20120227
Title: Relationship between paraoxonase and homocysteine: crossroads of oxidative diseases.
Journal: Archives of medical science : AMS 20120227
Title: The association of statins and taxanes: an efficient combination trigger of cancer cell apoptosis.
Journal: British journal of cancer 20120214
Title: PPARγ contributes to PKM2 and HK2 expression in fatty liver.
Journal: Nature communications 20120214
Title: Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.
Journal: Nature cell biology 20120212
Title: Proteomics and bioinformatics analysis of lovastatin-induced differentiation in ARO cells.
Journal: Journal of proteomics 20120202
Title: Synergistic inhibitory effect of apomine and lovastatin on osteosarcoma cell growth.
Journal: Cancer 20120201
Title: Adverse events associated with individual statin treatments for cardiovascular disease: an indirect comparison meta-analysis.
Journal: QJM : monthly journal of the Association of Physicians 20120201
Title: A review of the rationale for additional therapeutic interventions to attain lower LDL-C when statin therapy is not enough.
Journal: Current atherosclerosis reports 20120201
Title: Explication of interactions between HMGCR isoform 2 and various statins through In silico modeling and docking.
Journal: Computers in biology and medicine 20120201
Title: Identification and characterization of Penicillium citrinum VeA and LaeA as global regulators for ML-236B production.
Journal: Current genetics 20120201
Title: Cytotoxic dehydromonacolins from red yeast rice.
Journal: Journal of agricultural and food chemistry 20120201
Title: HMG-CoA reductase inhibitors (statins) reduce hypertrophic scar formation in a rabbit ear wounding model.
Journal: Plastic and reconstructive surgery 20120201
Title: Pravastatin reduces steroid-induced osteonecrosis of the femoral head in SHRSP rats.
Journal: Acta orthopaedica 20120201
Title: Selecting an invertebrate model host for the study of fungal pathogenesis.
Journal: PLoS pathogens 20120201
Title: ChLae1 and ChVel1 regulate T-toxin production, virulence, oxidative stress response, and development of the maize pathogen Cochliobolus heterostrophus.
Journal: PLoS pathogens 20120201
Title: Acute rhabdomyolysis caused by combination therapy with atorvastatin and warfarin.
Journal: British journal of hospital medicine (London, England : 2005) 20120201
Title: Suppression of esophageal cancer cell growth using curcumin, (-)-epigallocatechin-3-gallate and lovastatin.
Journal: World journal of gastroenterology 20120114
Title: Trillin, a steroidal saponin isolated from the rhizomes of Dioscorea nipponica, exerts protective effects against hyperlipidemia and oxidative stress.
Journal: Journal of ethnopharmacology 20120106
Title: Fast screening of lovastatin in red yeast rice products by flow injection tandem mass spectrometry.
Journal: Journal of pharmaceutical and biomedical analysis 20120105
Title: [Specific considerations on the prescription and therapeutic interchange of statins].
Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20120101
Title: Hypertriglyceridemia, Metabolic Syndrome, and Cardiovascular Disease in HIV-Infected Patients: Effects of Antiretroviral Therapy and Adipose Tissue Distribution.
Journal: International journal of vascular medicine 20120101
Title: Understanding postprandial inflammation and its relationship to lifestyle behaviour and metabolic diseases.
Journal: International journal of vascular medicine 20120101
Title: Prospective analysis of association between use of statins or other lipid-lowering agents and colorectal cancer risk.
Journal: Annals of epidemiology 20120101
Title: The PPARγ Agonist Rosiglitazone Is Antifibrotic for Scleroderma Lung Fibroblasts: Mechanisms of Action and Differential Racial Effects.
Journal: Pulmonary medicine 20120101
Title: Analysis of the role of RhoGDI1 and isoprenylation in the degradation of RhoGTPases.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Non-alcoholic Fatty liver disease: the bile Acid-activated farnesoid x receptor as an emerging treatment target.
Journal: Journal of lipids 20120101
Title: The long-term effect of statins on the risk of new-onset diabetes mellitus in elderly Taiwanese patients with hypertension and dyslipidaemia: a retrospective longitudinal cohort study.
Journal: Drugs & aging 20120101
Title: A systematic review of economic evaluations of interventions to tackle cardiovascular disease in low- and middle-income countries.
Journal: BMC public health 20120101
Title: Cancer metabolism: current perspectives and future directions.
Journal: Cell death & disease 20120101
Title: Exogenously-added copper/zinc superoxide dismutase rescues damage of endothelial cells from lethal irradiation.
Journal: Journal of clinical biochemistry and nutrition 20120101
Title: Lipid disorders in elderly hypertensive patients.
Journal: International journal of hypertension 20120101
Title: Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer.
Journal: Cell death & disease 20120101
Title: Evidence-based prediction of statin use with lipid-panel data from the National Health and Nutrition Examination Survey.
Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20120101
Title: Lack of effect of lowering LDL cholesterol on cancer: meta-analysis of individual data from 175,000 people in 27 randomised trials of statin therapy.
Journal: PloS one 20120101
Title: Impact of circulating cholesterol levels on growth and intratumoral androgen concentration of prostate tumors.
Journal: PloS one 20120101
Title: Managing atrial fibrillation in the elderly: critical appraisal of dronedarone.
Journal: Clinical interventions in aging 20120101
Title: Pharmacokinetics of venlafaxine and its major metabolite o-desmethylvenlafaxine in freely moving mice using automated dosing/sampling system.
Journal: Indian journal of pharmacology 20120101
Title: Antihyperlipidemic activity of Salacia chinensis root extracts in triton-induced and atherogenic diet-induced hyperlipidemic rats.
Journal: Indian journal of pharmacology 20120101
Title: Iron - A Key Nexus in the Virulence of Aspergillus fumigatus.
Journal: Frontiers in microbiology 20120101
Title: An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes.
Journal: International journal of biological sciences 20120101
Title: The effect of statin therapy in stroke outcome: a double blind clinical trial.
Journal: International journal of preventive medicine 20120101
Title: The functions of myosin II and myosin V homologs in tip growth and septation in Aspergillus nidulans.
Journal: PloS one 20120101
Title: Quantification and clustering of phenotypic screening data using time-series analysis for chemotherapy of schistosomiasis.
Journal: BMC genomics 20120101
Title: The relation between serum lipids and lutein and zeaxanthin in the serum and retina: results from cross-sectional, case-control and case study designs.
Journal: Lipids in health and disease 20120101
Title: Cocoa, hazelnuts, sterols and soluble fiber cream reduces lipids and inflammation biomarkers in hypertensive patients: a randomized controlled trial.
Journal: PloS one 20120101
Title: Assessment of extracts from red yeast rice for herb-drug interaction by in-vitro and in-vivo assays.
Journal: Scientific reports 20120101
Title: Comparison of prescription drug costs in the United States and the United Kingdom, Part 1: statins.
Journal: Pharmacotherapy 20120101
Title: NMR evaluation of total statin content and HMG-CoA reductase inhibition in red yeast rice (Monascus spp.) food supplements.
Journal: Chinese medicine 20120101
Title: Rosuvastatin: a review of the pharmacology and clinical effectiveness in cardiovascular disease.
Journal: Clinical Medicine Insights. Cardiology 20120101
Title: From neurodevelopment to neurodegeneration: the interaction of neurofibromin and valosin-containing protein/p97 in regulation of dendritic spine formation.
Journal: Journal of biomedical science 20120101
Title: Perturbation of cytokinin and ethylene-signalling pathways explain the strong rooting phenotype exhibited by Arabidopsis expressing the Schizosaccharomyces pombe mitotic inducer, cdc25.
Journal: BMC plant biology 20120101
Title: LIPITENSION: Interplay between dyslipidemia and hypertension.
Journal: Indian journal of endocrinology and metabolism 20120101
Title: The PPAR-γ agonist pioglitazone protects cortical neurons from inflammatory mediators via improvement in peroxisomal function.
Journal: Journal of neuroinflammation 20120101
Title: [Cholesterol-degrading in mice by Lactobacillus plantarum LpT1 and LpT2 in vivo].
Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20120101
Title: New therapeutic approaches by using microorganism-derived compounds.
Journal: Current medicinal chemistry 20120101
Title: Involvement of the ubiquitin-proteasome system in the formation of experimental postsurgical peritoneal adhesions.
Journal: Mediators of inflammation 20120101
Title: Study of the effects of total flavonoids of Astragalus on atherosclerosis formation and potential mechanisms.
Journal: Oxidative medicine and cellular longevity 20120101
Title: Elucidation of the Rotavirus NSP4-Caveolin-1 and -Cholesterol Interactions Using Synthetic Peptides.
Journal: Journal of amino acids 20120101
Title: Screening of medicinal higher Basidiomycetes mushrooms from Turkey for lovastatin production.
Journal: International journal of medicinal mushrooms 20120101
Title: Abnormal barrier function in the pathogenesis of ichthyosis: therapeutic implications for lipid metabolic disorders.
Journal: Clinics in dermatology 20120101
Title: Efficacy of short-term high-dose statin in preventing contrast-induced nephropathy: a meta-analysis of seven randomized controlled trials.
Journal: PloS one 20120101
Title: A comparative clinical study of hypolipidemic efficacy of Amla (Emblica officinalis) with 3-hydroxy-3-methylglutaryl-coenzyme-A reductase inhibitor simvastatin.
Journal: Indian journal of pharmacology 20120101
Title: A comparative effect of atorvastatin with other statins in patients of hyperlipidemia.
Journal: Indian journal of pharmacology 20120101
Title: Novel therapies in glioblastoma.
Journal: Neurology research international 20120101
Title: Investigation of antimicrobial activity and statistical optimization of Bacillus subtilis SPB1 biosurfactant production in solid-state fermentation.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Ethanolic Extract of Vitis thunbergii Exhibits Lipid Lowering Properties via Modulation of the AMPK-ACC Pathway in Hypercholesterolemic Rabbits.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Cell cycle inhibition without disruption of neurogenesis is a strategy for treatment of aberrant cell cycle diseases: an update.
Journal: TheScientificWorldJournal 20120101
Title: An overview of the evidence and mechanisms of herb-drug interactions.
Journal: Frontiers in pharmacology 20120101
Title: A systematic review of xuezhikang, an extract from red yeast rice, for coronary heart disease complicated by dyslipidemia.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Systematic analysis of cell cycle effects of common drugs leads to the discovery of a suppressive interaction between gemfibrozil and fluoxetine.
Journal: PloS one 20120101
Title: Reactive oxygen species and inhibitors of inflammatory enzymes, NADPH oxidase, and iNOS in experimental models of Parkinson's disease.
Journal: Mediators of inflammation 20120101
Title: Synthesis of naringin 6'-ricinoleate using immobilized lipase.
Journal: Chemistry Central journal 20120101
Title: Public health concerns for anti-obesity medicines imported for personal use through the internet: a cross-sectional study.
Journal: BMJ open 20120101
Title: Discontinuation of statin therapy in older people: does a cancer diagnosis make a difference? An observational cohort study using data linkage.
Journal: BMJ open 20120101
Title: BMP-2 up-regulates PTEN expression and induces apoptosis of pulmonary artery smooth muscle cells under hypoxia.
Journal: PloS one 20120101
Title: Do statins improve outcomes in patients with asthma on inhaled corticosteroid therapy? A retrospective cohort analysis.
Journal: BMJ open 20120101
Title: Plasticity and mTOR: towards restoration of impaired synaptic plasticity in mTOR-related neurogenetic disorders.
Journal: Neural plasticity 20120101
Title: Investigation of the biosynthetic potential of endophytes in traditional Chinese anticancer herbs.
Journal: PloS one 20120101
Title: Deciphering the molecular functions of sterols in cellulose biosynthesis.
Journal: Frontiers in plant science 20120101
Title: Epigenetics modifications and therapeutic prospects in human thyroid cancer.
Journal: Frontiers in endocrinology 20120101
Title: Optimization of the Nutritional Parameters for Enhanced Production of B. subtilis SPB1 Biosurfactant in Submerged Culture Using Response Surface Methodology.
Journal: Biotechnology research international 20120101
Title: LDL-apheresis: technical and clinical aspects.
Journal: TheScientificWorldJournal 20120101
Title: PPARs: Interference with Warburg' Effect and Clinical Anticancer Trials.
Journal: PPAR research 20120101
Title: Effect of levels of acetate on the mevalonate pathway of Borrelia burgdorferi.
Journal: PloS one 20120101
Title: Early dengue virus protein synthesis induces extensive rearrangement of the endoplasmic reticulum independent of the UPR and SREBP-2 pathway.
Journal: PloS one 20120101
Title: The effects of dietary intervention on HIV dyslipidaemia: a systematic review and meta-analysis.
Journal: PloS one 20120101
Title: Statistical optimization of process variables for antibiotic activity of Xenorhabdus bovienii.
Journal: PloS one 20120101
Title: Simvastatin reduces endotoxin-induced acute lung injury by decreasing neutrophil recruitment and radical formation.
Journal: PloS one 20120101
Title: Lovastatin modulates glycogen synthase kinase-3β pathway and inhibits mossy fiber sprouting after pilocarpine-induced status epilepticus.
Journal: PloS one 20120101
Title: Phylogenomic and domain analysis of iterative polyketide synthases in Aspergillus species.
Journal: Evolutionary bioinformatics online 20120101
Title: Effect of hydroalcoholic extract of Hypericum perforatum on selected traditional and novel biochemical factors of cardiovascular diseases and atherosclerotic lesions in hypercholesterolemic rabbits: A comparison between the extract and lovastatin.
Journal: Journal of pharmacy & bioallied sciences 20120101
Title: Effects of tocotrienol and lovastatin combination on osteoblast and osteoclast activity in estrogen-deficient osteoporosis.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: A survey of the FDA's AERS database regarding muscle and tendon adverse events linked to the statin drug class.
Journal: PloS one 20120101
Title: Differential effects of lovastatin on cisplatin responses in normal human mesothelial cells versus cancer cells: implication for therapy.
Journal: PloS one 20120101
Title: Lovastatin induces multiple stress pathways including LKB1/AMPK activation that regulate its cytotoxic effects in squamous cell carcinoma cells.
Journal: PloS one 20120101
Title: Transgelin 2 participates in lovastatin-induced anti-angiogenic effects in endothelial cells through a phosphorylated myosin light chain-related mechanism.
Journal: PloS one 20120101
Title: Regulatory cross talk and microbial induction of fungal secondary metabolite gene clusters.
Journal: Methods in enzymology 20120101
Title: Lovastatin production by Aspergillus terreus using agro-biomass as substrate in solid state fermentation.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Quantitative proteomic analysis revealed lovastatin-induced perturbation of cellular pathways in HL-60 cells.
Journal: Journal of proteome research 20111202
Title: CKD-MBD after kidney transplantation.
Journal: Pediatric nephrology (Berlin, Germany) 20111201
Title: Association of lower total bilirubin level with statin usage: the United States National Health and Nutrition Examination Survey 1999-2008.
Journal: Atherosclerosis 20111201
Title: Therapeutics for childhood neurofibromatosis type 1 and type 2.
Journal: Current treatment options in neurology 20111201
Title: Inhibition of neuronal cholesterol biosynthesis with lovastatin leads to impaired synaptic vesicle release even in the presence of lipoproteins or geranylgeraniol.
Journal: Journal of neurochemistry 20111201
Title: Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the Rho/ROCK-mediated pathway.
Journal: Biochemical pharmacology 20111201
Title: Regulation of apoptosis in human melanoma and neuroblastoma cells by statins, sodium arsenite and TRAIL: a role of combined treatment versus monotherapy.
Journal: Apoptosis : an international journal on programmed cell death 20111201
Title: Preparation and characterization of a lovastatin-loaded protein-free nanostructured lipid carrier resembling high-density lipoprotein and evaluation of its targeting to foam cells.
Journal: AAPS PharmSciTech 20111201
Title: Long-term curcumin administration protects against atherosclerosis via hepatic regulation of lipoprotein cholesterol metabolism.
Journal: Molecular nutrition & food research 20111201
Title: Valosin-containing protein and neurofibromin interact to regulate dendritic spine density.
Journal: The Journal of clinical investigation 20111201
Title: Fatal rhabdomyolysis in a patient with liver cirrhosis after switching from simvastatin to fluvastatin.
Journal: Journal of Korean medical science 20111201
Title: Floral odor bouquet loses its ant repellent properties after inhibition of terpene biosynthesis.
Journal: Journal of chemical ecology 20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins.
Journal: Oncotarget 20111201
Title: Recent advances in mechanisms and treatments of airway remodeling in asthma: a message from the bench side to the clinic.
Journal: The Korean journal of internal medicine 20111201
Title: Prediction of drug combinations by integrating molecular and pharmacological data.
Journal: PLoS computational biology 20111201
Title: [Red yeast rice can lower cholesterol but should not replace established therapy].
Journal: Lakartidningen 20111201
Title: [Achievement of therapeutic target in subjects on statin treatment in clinical practice. Results of the STAR (Statins Target Assessment in Real practice) study].
Journal: Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20111201
Title: Discovery and synthesis of novel substituted benzocoumarins as orally active lipid modulating agents.
Journal: Bioorganic & medicinal chemistry letters 20111115
Title: Phylogeny of Penicillium and the segregation of Trichocomaceae into three families.
Journal: Studies in mycology 20111115
Title: Cost-effectiveness of the use of low- and high-potency statins in people at low cardiovascular risk.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20111108
Title: Pathogenesis-based therapy reverses cutaneous abnormalities in an inherited disorder of distal cholesterol metabolism.
Journal: The Journal of investigative dermatology 20111101
Title: Fluvastatin modulates renal water reabsorption in vivo through increased AQP2 availability at the apical plasma membrane of collecting duct cells.
Journal: Pflugers Archiv : European journal of physiology 20111101
Title: Statins inhibit iNOS-mediated microbicidal potential of activated monocyte-derived dendritic cells by an IFN-β-dependent mechanism.
Journal: European journal of immunology 20111101
Title: A novel bisphosphonate inhibitor of squalene synthase combined with a statin or a nitrogenous bisphosphonate in vitro.
Journal: Journal of lipid research 20111101
Title: Efficient bioconversion of compactin to pravastatin by the quinoline-degrading microorganism Pseudonocardia carboxydivorans isolated from petroleum-contaminated soil.
Journal: Bioresource technology 20111101
Title: Statin effects on regulatory and proinflammatory factors in chronic idiopathic urticaria.
Journal: Clinical and experimental immunology 20111101
Title: A cost-benefit analysis of lipid standardization in the United States.
Journal: Preventing chronic disease 20111101
Title: Modifiers of symptomatic embolic risk in infective endocarditis.
Journal: Mayo Clinic proceedings 20111101
Title: Preparation of lovastatin matrix sustained-release pellets by extrusion-spheronization combined with microcrystal dispersion technique.
Journal: Archives of pharmacal research 20111101
Title: Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I.
Journal: Human molecular genetics 20111015
Title: Highly efficient release of lovastatin from poly(lactic-co-glycolic acid) nanoparticles enhances bone repair in rats.
Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20111001
Title: Pleiotropic effects of a schweinfurthin on isoprenoid homeostasis.
Journal: Lipids 20111001
Title: Thalidomide, dexamethasone and lovastatin with autologous stem cell transplantation as a salvage immunomodulatory therapy in patients with relapsed and refractory multiple myeloma.
Journal: Annals of hematology 20111001
Title: Induction of a high-yield lovastatin mutant of Aspergillus terreus by ¹²C⁶⁺ heavy-ion beam irradiation and the influence of culture conditions on lovastatin production under submerged fermentation.
Journal: Applied biochemistry and biotechnology 20111001
Title: Subcellular localization and regulation of StarD4 protein in macrophages and fibroblasts.
Journal: Biochimica et biophysica acta 20111001
Title: The cytostatic effects of lovastatin on ACC-MESO-1 cells.
Journal: The Journal of surgical research 20111001
Title: Discovery of a new class of HMG-CoA reductase inhibitor from Polyalthia longifolia as potential lipid lowering agent.
Journal: European journal of medicinal chemistry 20111001
Title: Antioxidant effect of red mould rice in hypercholesterolemic Wistar male rats.
Journal: Cell biochemistry and function 20111001
Title: Lovastatin as treatment for neurocognitive deficits in neurofibromatosis type 1: phase I study.
Journal: Pediatric neurology 20111001
Title: Adverse drug reactions caused by drug-drug interactions reported to Croatian Agency for Medicinal Products and Medical Devices: a retrospective observational study.
Journal: Croatian medical journal 20111001
Title: [Rhabdomyolysis related to statin and seizures: report of 3 cases].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20111001
Title: [Study on effect of berberine on modulating lipid and CPT I A gene expression].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111001
Title: Are patients undergoing treatment of hyperlipidaemia with statins the best candidates for early cardiac rehabilitation?
Journal: Archives of medical science : AMS 20111001
Title: Osteoprotective effect of Monascus-fermented dioscorea in ovariectomized rat model of postmenopausal osteoporosis.
Journal: Journal of agricultural and food chemistry 20110914
Title: The 2',4',6'-trihydroxyacetophenone isolated from Myrcia multiflora has antiobesity and mixed hypolipidemic effects with the reduction of lipid intestinal absorption.
Journal: Planta medica 20110901
Title: Cholesterol-independent neuroprotective and neurotoxic activities of statins: perspectives for statin use in Alzheimer disease and other age-related neurodegenerative disorders.
Journal: Pharmacological research 20110901
Title: Beneficial effects of combinatorial micronutrition on body fat and atherosclerosis in mice.
Journal: Cardiovascular research 20110901
Title: AAPS workshop report: strategies to address therapeutic protein-drug interactions during clinical development.
Journal: The AAPS journal 20110901
Title: Lipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinib.
Journal: Journal of cellular physiology 20110901
Title: Xuezhikang, extract of red yeast rice, inhibited tissue factor and hypercoagulable state through suppressing nicotinamide adenine dinucleotide phosphate oxidase and extracellular signal-regulated kinase activation.
Journal: Journal of cardiovascular pharmacology 20110901
Title: Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients.
Journal: Annals of neurology 20110901
Title: Evaluation of a pharmacist-managed amiodarone monitoring program.
Journal: Journal of managed care pharmacy : JMCP 20110901
Title: Genomic and proteomic analyses of the fungus Arthrobotrys oligospora provide insights into nematode-trap formation.
Journal: PLoS pathogens 20110901
Title: The receptor tyrosine kinase Alk controls neurofibromin functions in Drosophila growth and learning.
Journal: PLoS genetics 20110901
Title: Neurotoxic effect of statins on mouse neuroblastoma NB2a cell line.
Journal: European review for medical and pharmacological sciences 20110901
Title: [Clinical study on the treatment of abnormal blood lipids complicated with carotid atherosclerosis with lipid-reducing red rice minute powder: a randomized controlled trial].
Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20110901
Title: Inhibition of endothelial adhesion molecule expression by Monascus purpureus-fermented rice metabolites, monacolin K, ankaflavin, and monascin.
Journal: Journal of the science of food and agriculture 20110815
Title: Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist.
Journal: The Biochemical journal 20110815
Title: Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs.
Journal: The pharmacogenomics journal 20110801
Title: Prelamin A-mediated recruitment of SUN1 to the nuclear envelope directs nuclear positioning in human muscle.
Journal: Cell death and differentiation 20110801
Title: Characterization of environmental chemicals with potential for DNA damage using isogenic DNA repair-deficient chicken DT40 cell lines.
Journal: Environmental and molecular mutagenesis 20110801
Title: Survivin upregulation, dependent on leptin-EGFR-Notch1 axis, is essential for leptin-induced migration of breast carcinoma cells.
Journal: Endocrine-related cancer 20110801
Title: Parkinson's disease mouse models in translational research.
Journal: Mammalian genome : official journal of the International Mammalian Genome Society 20110801
Title: Disturbed subjective sleep characteristics in adult patients with long-standing type 1 diabetes mellitus.
Journal: Diabetologia 20110801
Title: Effects of farnesyl pyrophosphate accumulation on calvarial osteoblast differentiation.
Journal: Endocrinology 20110801
Title: Juvenile toxicity assessment of open-acid lovastatin in rats.
Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20110801
Title: Function of MRP1/ABCC1 is not dependent on cholesterol or cholesterol-stabilized lipid rafts.
Journal: The Biochemical journal 20110801
Title: SR-PSOX at sites predisposed to atherosclerotic lesion formation mediates monocyte-endothelial cell adhesion.
Journal: Atherosclerosis 20110801
Title: Inhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity.
Journal: Cell death & disease 20110801
Title: Anti-apoptotic machinery protects the necrotrophic fungus Botrytis cinerea from host-induced apoptotic-like cell death during plant infection.
Journal: PLoS pathogens 20110801
Title: Diallyl disulphide and lovastatin: effects on energy and protein utilisation in, as well as methane emission from, sheep.
Journal: Archives of animal nutrition 20110801
Title: Comparison of different extraction methods for the determination of statin drugs in wastewater and river water by HPLC/Q-TOF-MS.
Journal: Talanta 20110715
Title: Rhadbomyolysis associated with co-administration of danazol and lovastatin.
Journal: British journal of clinical pharmacology 20110701
Title: The farnesyltransferase inhibitors tipifarnib and lonafarnib inhibit cytokines secretion in a cellular model of mevalonate kinase deficiency.
Journal: Pediatric research 20110701
Title: Use of transporter knockdown Caco-2 cells to investigate the in vitro efflux of statin drugs.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110701
Title: Antitumor effects of the combination of cholesterol reducing drugs.
Journal: Oncology reports 20110701
Title: Ruminal methane inhibition potential of various pure compounds in comparison with garlic oil as determined with a rumen simulation technique (Rusitec).
Journal: The British journal of nutrition 20110701
Title: Is there a treatment advantage when paclitaxel and lovastatin are combined to dose anaplastic thyroid carcinoma cell lines?
Journal: Thyroid : official journal of the American Thyroid Association 20110701
Title: Lovastatin and valproic acid additively attenuate cell invasion in ACC-MESO-1 cells.
Journal: Biochemical and biophysical research communications 20110701
Title: Trichothecenes: from simple to complex mycotoxins.
Journal: Toxins 20110701
Title: Antioxidant effects of Citrus aurantifolia (Christm) juice and peel extract on LDL oxidation.
Journal: Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110701
Title: New species in Aspergillus section Terrei.
Journal: Studies in mycology 20110630
Title: [Pharmaco-economic optimization of cholesterol-lowering treatment with statins].
Journal: Medicina clinica 20110625
Title: Polysorbates as novel lipid-modulating candidates for reducing serum total cholesterol and low-density lipoprotein levels in hyperlipidemic C57BL/6J mice and rats.
Journal: European journal of pharmacology 20110625
Title: Statins and prostate cancer diagnosis and grade in a veterans population.
Journal: Journal of the National Cancer Institute 20110608
Title: Lovastatin inhibits thrombospondin-1-induced smooth muscle cell chemotaxis.
Journal: The Journal of surgical research 20110601
Title: Mode of action of parasporin-4, a cytocidal protein from Bacillus thuringiensis.
Journal: Biochimica et biophysica acta 20110601
Title: A clone-based transcriptomics approach for the identification of genes relevant for itaconic acid production in Aspergillus.
Journal: Fungal genetics and biology : FG & B 20110601
Title: Role of intestinal cytochrome P450 (P450) in modulating the bioavailability of oral lovastatin: insights from studies on the intestinal epithelium-specific P450 reductase knockout mouse.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110601
Title: Double oxidation of the cyclic nonaketide dihydromonacolin L to monacolin J by a single cytochrome P450 monooxygenase, LovA.
Journal: Journal of the American Chemical Society 20110601
Title: Specific inhibitions of annonaceous acetogenins on class II 3-hydroxy-3-methylglutaryl coenzyme A reductase from Streptococcus pneumoniae.
Journal: Bioorganic & medicinal chemistry 20110601
Title: Niacin extended-release therapy in phase III clinical trials is associated with relatively low rates of drug discontinuation due to flushing and treatment-related adverse events: a pooled analysis.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20110601
Title: Lovastatin causes diminished PSA secretion by inhibiting AR expression and function in LNCaP prostate cancer cells.
Journal: Urology 20110601
Title: Antihyperlipidemic activities of Pleurotus ferulae on biochemical and histological function in hypercholesterolemic rats.
Journal: Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110601
Title: [Experimental studies on blood lipid regulating effects of shuanghua granules].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110601
Title: 2-Aminophenoxazine-3-one and 2-amino-4,4α-dihydro-4α,7-dimethyl-3H-phenoxazine-3-one cause cellular apoptosis by reducing higher intracellular pH in cancer cells.
Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110511
Title: Cytotoxic effect of different statins and thiazolidinediones on malignant glioma cells.
Journal: Cancer chemotherapy and pharmacology 20110501
Title: Host cholesterol synthesis contributes to growth of intracellular Toxoplasma gondii in macrophages.
Journal: The Journal of veterinary medical science 20110501
Title: Development of natural anti-tumor drugs by microorganisms.
Journal: Journal of bioscience and bioengineering 20110501
Title: Bisphosphonates induce autophagy by depleting geranylgeranyl diphosphate.
Journal: The Journal of pharmacology and experimental therapeutics 20110501
Title: Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells.
Journal: Cancer letters 20110501
Title: Adherence to single-pill combination versus multiple-pill combination lipid-modifying therapy among patients with mixed dyslipidemia in a managed care population.
Journal: Current medical research and opinion 20110501
Title: Statins downregulate K6a promoter activity: a possible therapeutic avenue for pachyonychia congenita.
Journal: The Journal of investigative dermatology 20110501
Title: Decrease in dipeptidyl peptidase IV activity is linked to the efficacy of differentiating compounds in follicular thyroid carcinoma cell lines.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20110501
Title: Native low-density lipoprotein-dependent interleukin-8 production through pertussis toxin-sensitive G-protein coupled receptors and hydrogen peroxide generation contributes to migration of human aortic smooth muscle cells.
Journal: Yonsei medical journal 20110501
Title: Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells.
Journal: Experimental biology and medicine (Maywood, N.J.) 20110501
Title: Effects of ezetimibe added to ongoing statin therapy on C-reactive protein levels in hypercholesterolemic patients.
Journal: Korean circulation journal 20110501
Title: Isoprenoid biosynthetic pathway inhibition disrupts monoclonal protein secretion and induces the unfolded protein response pathway in multiple myeloma cells.
Journal: Leukemia research 20110401
Title: Lovastatin promotes redifferentiation of human nucleus pulposus cells during expansion in monolayer culture.
Journal: Artificial organs 20110401
Title: The effect of lovastatin on oxidative stress and antioxidant enzymes in hydrogen peroxide intoxicated rat.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110401
Title: Lactone form 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) stimulate the osteoblastic differentiation of mouse periodontal ligament cells via the ERK pathway.
Journal: Journal of periodontal research 20110401
Title: Simvastatin prevents skeletal metastasis of breast cancer by an antagonistic interplay between p53 and CD44.
Journal: The Journal of biological chemistry 20110401
Title: Aborted autophagy and nonapoptotic death induced by farnesyl transferase inhibitor and lovastatin.
Journal: The Journal of pharmacology and experimental therapeutics 20110401
Title: Statins inhibit T-acute lymphoblastic leukemia cell adhesion and migration through Rap1b.
Journal: Journal of leukocyte biology 20110401
Title: An eight-week trial investigating the efficacy and tolerability of atorvastatin for children and adolescents with heterozygous familial hypercholesterolemia.
Journal: Pediatric cardiology 20110401
Title: Chinese red yeast rice inhibition of prostate tumor growth in SCID mice.
Journal: Cancer prevention research (Philadelphia, Pa.) 20110401
Title: Arecoline stimulated Cyr61 production in human gingival epithelial cells: inhibition by lovastatin.
Journal: Oral oncology 20110401
Title: Geranylgeranylation facilitates proteasomal degradation of rho G-proteins in human trabecular meshwork cells.
Journal: Investigative ophthalmology & visual science 20110325
Title: Demographic determinants of response to statin medications.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110315
Title: Aspergillus as a multi-purpose cell factory: current status and perspectives.
Journal: Biotechnology letters 20110301
Title: Lovastatin sensitizes lung cancer cells to ionizing radiation: modulation of molecular pathways of radioresistance and tumor suppression.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110301
Title: Structure elucidation and complete NMR spectral assignment of an unusual aromatic monacolin analog from Monascus purpureus-fermented rice.
Journal: Magnetic resonance in chemistry : MRC 20110301
Title: Azathioprine-induced fever in sarcoidosis.
Journal: The Annals of pharmacotherapy 20110301
Title: Effects of carnitine and coenzyme Q10 on lipid profile and serum levels of lipoprotein(a) in maintenance hemodialysis patients on statin therapy.
Journal: Iranian journal of kidney diseases 20110301
Title: Survival rates of early-stage HCV-related liver cirrhosis patients without hepatocellular carcinoma are decreased by alcohol.
Journal: Journal of clinical biochemistry and nutrition 20110301
Title: Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis.
Journal: PLoS biology 20110301
Title: Depressogenic effects of medications: a review.
Journal: Dialogues in clinical neuroscience 20110301
Title: Thrombotic Thrombocytopenic Purpura associated with Clopidogrel: a case report and review of the literature.
Journal: Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110301
Title: C-reactive protein concentration and the vascular benefits of statin therapy: an analysis of 20,536 patients in the Heart Protection Study.
Journal: Lancet (London, England) 20110205
Title: Promotion of Monacolin K production by Agrobacterium tumefaciens-mediated transformation in Monascus albidus 9901.
Journal: Current microbiology 20110201
Title: Lovastatin enhances paraoxonase enzyme activity and quells low-density lipoprotein susceptibility to oxidation in type 2 diabetic nephropathy.
Journal: Clinical biochemistry 20110201
Title: Statin therapy in metabolic syndrome and hypertension post-JUPITER: what is the value of CRP?
Journal: Current atherosclerosis reports 20110201
Title: Suppression of statin effectiveness by copper and zinc in yeast and human cells.
Journal: Molecular bioSystems 20110201
Title: What combination therapy with a statin, if any, would you recommend?
Journal: Current atherosclerosis reports 20110201
Title: OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling.
Journal: Atherosclerosis 20110201
Title: Orthopaedic aspects of neurofibromatosis: update.
Journal: Current opinion in pediatrics 20110201
Title: Novel extended-release formulation of lovastatin by one-step melt granulation: in vitro and in vivo evaluation.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110201
Title: Approach to dyslipidemia, lipodystrophy, and cardiovascular risk in patients with HIV infection.
Journal: Current atherosclerosis reports 20110201
Title: Influence of one-year treatment with lovastatin on myocardial remodeling and ischemia in patients with coronary artery disease.
Journal: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20110201
Title: In vivo and in vitro anti-inflammatory and anti-nociceptive activities of lovastatin in rodents.
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20110201
Title: May lovastatin target both autism and epilepsy? A novel hypothesized treatment.
Journal: Epilepsy & behavior : E&B 20110201
Title: Progression of carotid artery intima-media thickness during 12 years in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study.
Journal: Diabetes 20110201
Title: Is red yeast rice safe and effective for lowering serum cholesterol?
Journal: Journal of the American Dietetic Association 20110201
Title: Lovastatin changes activities of lactate dehydrogenase A and B genes in rat myocardial cells.
Journal: Chinese medical journal 20110201
Title: Production of lovastatin by wild strains of Aspergillus terreus.
Journal: Natural product communications 20110201
Title: Letter: a retrospective study on the efficacy of a ten-milligram dosage of atorvastatin for treatment of hypercholesterolemia in type 2 diabetes mellitus patients (korean diabetes j 2010;34:359-67).
Journal: Diabetes & metabolism journal 20110201
Title: [Retention behavior of statins in microemulsion liquid chromatography].
Journal: Se pu = Chinese journal of chromatography 20110201
Title: Rosuvastatin reduces nonalcoholic fatty liver disease in patients with chronic hepatitis C treated with α-interferon and ribavirin: Rosuvastatin reduces NAFLD in HCV patients.
Journal: Hepatitis monthly 20110201
Title: FT-ICR-MS characterization of intermediates in the biosynthesis of the α-methylbutyrate side chain of lovastatin by the 277 kDa polyketide synthase LovF.
Journal: Biochemistry 20110118
Title: Development of biodegradable porous starch foam for improving oral delivery of poorly water soluble drugs.
Journal: International journal of pharmaceutics 20110117
Title: Lovastatin biosynthesis by Aspergillus terreus with the simultaneous use of lactose and glycerol in a discontinuous fed-batch culture.
Journal: Journal of biotechnology 20110110
Title: Construction of a novel expression vector in Pseudonocardia autotrophica and its application to efficient biotransformation of compactin to pravastatin, a specific HMG-CoA reductase inhibitor.
Journal: Biochemical and biophysical research communications 20110107
Title: Medical therapy for advanced pancreatic cancer: work in progress.
Journal: JOP : Journal of the pancreas 20110105
Title: Red Mold Rice Mitigates Oral Carcinogenesis in 7,12-Dimethyl-1,2-Benz[a]anthracene-Induced Oral Carcinogenesis in Hamster.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Statins: 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitors demonstrate anti-atherosclerotic character due to their antioxidant capacity.
Journal: Applied biochemistry and biotechnology 20110101
Title: Effects of bile salts on the lovastatin pharmacokinetics following oral administration to rats.
Journal: Drug delivery 20110101
Title: Proteomics of industrial fungi: trends and insights for biotechnology.
Journal: Applied microbiology and biotechnology 20110101
Title: Generation of human chiral metabolites of simvastatin and lovastatin by bacterial CYP102A1 mutants.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101
Title: Use of ultra high performance liquid chromatography-tandem mass spectrometry to demonstrate decreased serum statin levels after extracorporeal LDL-cholesterol elimination.
Journal: Journal of biomedicine & biotechnology 20110101
Title: Sterol regulatory element-binding protein 2 (SREBP2) activation after excess triglyceride storage induces chemerin in hypertrophic adipocytes.
Journal: Endocrinology 20110101
Title: Lovastatin decreases the synthesis of inflammatory mediators in the hippocampus and blocks the hyperthermia of rats submitted to long-lasting status epilepticus.
Journal: Epilepsy & behavior : E&B 20110101
Title: Statins have an early antiplatelet effect in patients with acute myocardial infarction.
Journal: Platelets 20110101
Title: Effect of hydroxymethylglutaryl-CoA reductase inhibitors on low-density lipoprotein cholesterol, interleukin-6, and high-sensitivity C-reactive protein in end-stage renal disease.
Journal: Iranian journal of kidney diseases 20110101
Title: Effects of lovastatin on the pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, in rats: possible role of cytochrome P450 3A4 and P-glycoprotein inhibition by lovastatin.
Journal: The Journal of pharmacy and pharmacology 20110101
Title: Transcription factors CgUPC2A and CgUPC2B regulate ergosterol biosynthetic genes in Candida glabrata.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20110101
Title: Simvastatin is the statin that most efficiently protects against kainate-induced excitotoxicity and memory impairment.
Journal: Journal of Alzheimer's disease : JAD 20110101
Title: Polyunsaturated fatty acids reduce fatty acid synthase and hydroxy-methyl-glutaryl CoA-reductase gene expression and promote apoptosis in HepG2 cell line.
Journal: Lipids in health and disease 20110101
Title: Statins reduce dengue virus production via decreased virion assembly.
Journal: Intervirology 20110101
Title: Cardiovascular prevention of cognitive decline.
Journal: Cardiology research and practice 20110101
Title: Restoration of cognitive deficits after statin feeding in TBI.
Journal: Restorative neurology and neuroscience 20110101
Title: Considering statins for cholesterol-reduction in children if lifestyle and diet changes do not improve their health: a review of the risks and benefits.
Journal: Vascular health and risk management 20110101
Title: Low density lipoprotein receptor gene Ava II polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations.
Journal: Lipids in health and disease 20110101
Title: Low level bacterial endotoxin activates two distinct signaling pathways in human peripheral blood mononuclear cells.
Journal: Journal of inflammation (London, England) 20110101
Title: Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage.
Journal: Malaria journal 20110101
Title: δ-Tocotrienol and quercetin reduce serum levels of nitric oxide and lipid parameters in female chickens.
Journal: Lipids in health and disease 20110101
Title: Effect of atorvastatin and clopidogrel co-administration after coronary stenting in korean patients with stable angina.
Journal: Korean circulation journal 20110101
Title: Topical preparations for pain relief: efficacy and patient adherence.
Journal: Journal of pain research 20110101
Title: Neurite outgrowth mediated by translation elongation factor eEF1A1: a target for antiplatelet agent cilostazol.
Journal: PloS one 20110101
Title: The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signals.
Journal: PloS one 20110101
Title: Synchronous high-performance liquid chromatography with a photodiode array detector and mass spectrometry for the determination of citrinin, monascin, ankaflavin, and the lactone and acid forms of monacolin K in red mold rice.
Journal: Journal of AOAC International 20110101
Title: Lipoprotein(a) Is the Best Single Marker in Assessing Unstable Angina Pectoris.
Journal: Cardiology research and practice 20110101
Title: Sex differences in drug disposition.
Journal: Journal of biomedicine & biotechnology 20110101
Title: Cell cycle-dependent induction of homologous recombination by a tightly regulated I-SceI fusion protein.
Journal: PloS one 20110101
Title: Apolipoprotein E epsilon-4 polymorphism is associated with younger age at referral to a lipidology clinic and a poorer response to lipid-lowering therapy.
Journal: Lipids in health and disease 20110101
Title: Statins: cardiovascular risk reduction in percutaneous coronary intervention-basic and clinical evidence of hyperacute use of statins.
Journal: International journal of hypertension 20110101
Title: Structure modeling and inhibitor prediction ofNADP oxidoreductase enzyme from Methanobrevibacter smithii.
Journal: Bioinformation 20110101
Title: Ticagrelor: the evidence for its clinical potential as an oral antiplatelet treatment for the reduction of major adverse cardiac events in patients with acute coronary syndromes.
Journal: Core evidence 20110101
Title: Clinical utility of rosuvastatin and other statins for cardiovascular risk reduction among the elderly.
Journal: Clinical interventions in aging 20110101
Title: Elevated expression of CDK4 in lung cancer.
Journal: Journal of translational medicine 20110101
Title: NCI60 cancer cell line panel data and RNAi analysis help identify EAF2 as a modulator of simvastatin and lovastatin response in HCT-116 cells.
Journal: PloS one 20110101
Title: Hypolipidemic potential of ethanolic extract of Verbesina encelioides Benth. roots.
Journal: Acta poloniae pharmaceutica 20110101
Title: Tocotrienols-induced inhibition of platelet thrombus formation and platelet aggregation in stenosed canine coronary arteries.
Journal: Lipids in health and disease 20110101
Title: Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males.
Journal: PloS one 20110101
Title: Impacts of membrane biophysics in Alzheimer's disease: from amyloid precursor protein processing to aβ Peptide-induced membrane changes.
Journal: International journal of Alzheimer's disease 20110101
Title: Pleiotropic effects of the HMG-CoA reductase inhibitors.
Journal: International journal of general medicine 20110101
Title: Clinical use and effectiveness of lipid lowering therapies in diabetes mellitus--an observational study from the Swedish National Diabetes Register.
Journal: PloS one 20110101
Title: Genes associated with prognosis after surgery for malignant pleural mesothelioma promote tumor cell survival in vitro.
Journal: BMC cancer 20110101
Title: Metabolic changes in skin caused by Scd1 deficiency: a focus on retinol metabolism.
Journal: PloS one 20110101
Title: Long-term use of fenofibrate is associated with increased prevalence of gallstone disease among patients undergoing maintenance hemodialysis.
Journal: Renal failure 20110101
Title: 'Humanized' stem cell culture techniques: the animal serum controversy.
Journal: Stem cells international 20110101
Title: Exogenous control of the expression of Group I CD1 molecules competent for presentation of microbial nonpeptide antigens to human T lymphocytes.
Journal: Clinical & developmental immunology 20110101
Title: Lipid lowering by hydroalcoholic extracts of Amaranthus caudatus L. induces regression of rabbits atherosclerotic lesions.
Journal: Lipids in health and disease 20110101
Title: Sphingosine kinase 1 regulates the Akt/FOXO3a/Bim pathway and contributes to apoptosis resistance in glioma cells.
Journal: PloS one 20110101
Title: Exploring dietitians' salient beliefs about shared decision-making behaviors.
Journal: Implementation science : IS 20110101
Title: Orange juice and its component, hesperidin, decrease the expression of multidrug resistance-associated protein 2 in rat small intestine and liver.
Journal: Journal of biomedicine & biotechnology 20110101
Title: Manipulation of pH shift to enhance the growth and antibiotic activity of Xenorhabdus nematophila.
Journal: Journal of biomedicine & biotechnology 20110101
Title: Clinical characteristics and evaluation of LDL-cholesterol treatment of the Spanish Familial Hypercholesterolemia Longitudinal Cohort Study (SAFEHEART).
Journal: Lipids in health and disease 20110101
Title: Aliskiren: An orally active renin inhibitor.
Journal: Journal of pharmacy & bioallied sciences 20110101
Title: Tolvaptan, hyponatremia, and heart failure.
Journal: International journal of nephrology and renovascular disease 20110101
Title: The role of fatty aldehyde dehydrogenase in epidermal structure and function.
Journal: Dermato-endocrinology 20110101
Title: Pathogenesis of the cutaneous phenotype in inherited disorders of cholesterol metabolism: Therapeutic implications for topical treatment of these disorders.
Journal: Dermato-endocrinology 20110101
Title: The RNA editing pattern of cox2 mRNA is affected by point mutations in plant mitochondria.
Journal: PloS one 20110101
Title: Relationship between a novel polymorphism of the C5L2 gene and coronary artery disease.
Journal: PloS one 20110101
Title: Effects of HMG-CoA reductase inhibitors on the pharmacokinetics of losartan and its main metabolite EXP-3174 in rats: possible role of CYP3A4 and P-gp inhibition by HMG-CoA reductase inhibitors.
Journal: Pharmacology 20110101
Title: A comparative study of the pharmacokinetics of traditional and automated dosing/blood sampling systems using gabapentin.
Journal: Indian journal of pharmacology 20110101
Title: Association of statin therapy with blood pressure control in hypertensive hypercholesterolemic outpatients in clinical practice.
Journal: Journal of cardiovascular disease research 20110101
Title: Generation of polyclonal antibody with high avidity to rosuvastatin and its use in development of highly sensitive ELISA for determination of rosuvastatin in plasma.
Journal: Chemistry Central journal 20110101
Title: Synchronization of HeLa cells.
Journal: Methods in molecular biology (Clifton, N.J.) 20110101
Title: Sensitivity to lovastatin of Saccharomyces cerevisiae strains deleted for pleiotropic drug resistance (PDR) genes.
Journal: Journal of molecular microbiology and biotechnology 20110101
Title: Stem cells for cardiac repair: status, mechanisms, and new strategies.
Journal: Stem cells international 20110101
Title: Treating statin-intolerant patients.
Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20110101
Title: Adherence with statins in a real-life setting is better when associated cardiovascular risk factors increase: a cohort study.
Journal: BMC cardiovascular disorders 20110101
Title: Antiatherogenic Potential of Nigella sativa Seeds and Oil in Diet-Induced Hypercholesterolemia in Rabbits.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: The roles of buyang huanwu decoction in anti-inflammation, antioxidation and regulation of lipid metabolism in rats with myocardial ischemia.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Depression in vascular pathologies: the neurologist's point of view.
Journal: Vascular health and risk management 20110101
Title: Morphology engineering--osmolality and its effect on Aspergillus niger morphology and productivity.
Journal: Microbial cell factories 20110101
Title: Deciphering the Actions of Antiparkinsonian and Antipsychotic Drugs on cAMP/DARPP-32 Signaling.
Journal: Frontiers in neuroanatomy 20110101
Title: Clopidogrel effectively suppresses endothelial microparticle generation induced by indoxyl sulfate via inhibition of the p38 mitogen-activated protein kinase pathway.
Journal: Blood purification 20110101
Title: Carotid plaque regression following 6-month statin therapy assessed by 3T cardiovascular magnetic resonance: comparison with ultrasound intima media thickness.
Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101
Title: Ligation of macrophage Fcγ receptors recapitulates the gene expression pattern of vulnerable human carotid plaques.
Journal: PloS one 20110101
Title: Assessment of cholesterol homeostasis in astrocytes and neurons.
Journal: Methods in molecular biology (Clifton, N.J.) 20110101
Title: Lysophosphatidic acid and lovastatin might protect kidney in renal I/R injury by downregulating MCP-1 in rat.
Journal: Renal failure 20110101
Title: Trypanosoma cruzi epimastigotes are able to store and mobilize high amounts of cholesterol in reservosome lipid inclusions.
Journal: PloS one 20110101
Title: Simultaneous enrichment of deglycosylated ginsenosides and monacolin K in red ginseng by fermentation with Monascus pilosus.
Journal: Bioscience, biotechnology, and biochemistry 20110101
Title: Mesenchymal stem cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cells.
Journal: Journal of biomedical science 20110101
Title: Anti-inflammatory effect of fluvastatin on IL-8 production induced by Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosis.
Journal: PloS one 20110101
Title: Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma.
Journal: Journal of experimental & clinical cancer research : CR 20110101
Title: Tacrolimus and 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors: An interaction study in CYP3A5 non-expressors, renal transplant recipients.
Journal: Indian journal of pharmacology 20110101
Title: Paraoxonase (PON1 and PON3) Polymorphisms: Impact on Liver Expression and Atorvastatin-Lactone Hydrolysis.
Journal: Frontiers in pharmacology 20110101
Title: Response by sex to statin plus ezetimibe or statin monotherapy: a pooled analysis of 22,231 hyperlipidemic patients.
Journal: Lipids in health and disease 20110101
Title: Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts.
Journal: Respiratory research 20110101
Title: Branch retinal vein occlusion associated with quetiapine fumarate.
Journal: BMC ophthalmology 20110101
Title: Treatment of allergic asthma: modulation of Th2 cells and their responses.
Journal: Respiratory research 20110101
Title: Treatment of an adrenomyeloneuropathy patient with Lorenzo's oil and supplementation with docosahexaenoic acid--a case report.
Journal: Lipids in health and disease 20110101
Title: Striatal Signaling in L-DOPA-Induced Dyskinesia: Common Mechanisms with Drug Abuse and Long Term Memory Involving D1 Dopamine Receptor Stimulation.
Journal: Frontiers in neuroanatomy 20110101
Title: Stepwise approach to myopathy in systemic disease.
Journal: Frontiers in neurology 20110101
Title: Synthesis, characterization and quantification of simvastatin metabolites and impurities.
Journal: Scientia pharmaceutica 20110101
Title: Three new compounds from Aspergillus terreus PT06-2 grown in a high salt medium.
Journal: Marine drugs 20110101
Title: Emerging therapies for severe asthma.
Journal: BMC medicine 20110101
Title: Formulation and evaluation of solid lipid nanoparticles of ramipril.
Journal: Journal of young pharmacists : JYP 20110101
Title: Remembering what's new in Alzheimer's management.
Journal: Journal of pharmacology & pharmacotherapeutics 20110101
Title: High Sensitivity C - Reactive Protein is Associated with Diastolic Dysfunction in Young African Americans without Clinically Evident Cardiac Disease.
Journal: The open cardiovascular medicine journal 20110101
Title: Potential role of differential medication use in explaining excess risk of cardiovascular events and death associated with chronic kidney disease: a cohort study.
Journal: BMC nephrology 20110101
Title: The hedgehog receptor patched is involved in cholesterol transport.
Journal: PloS one 20110101
Title: Neuronal (bi)polarity as a self-organized process enhanced by growing membrane.
Journal: PloS one 20110101
Title: Exposure to statins and risk of common cancers: a series of nested case-control studies.
Journal: BMC cancer 20110101
Title: Administration of simvastatin after kainic acid-induced status epilepticus restrains chronic temporal lobe epilepsy.
Journal: PloS one 20110101
Title: Antioxidant and inflammatory aspects of lipoprotein-associated phospholipase A₂ (Lp-PLA₂): a review.
Journal: Lipids in health and disease 20110101
Title: Pulsed electromagnetic fields stimulation prevents steroid-induced osteonecrosis in rats.
Journal: BMC musculoskeletal disorders 20110101
Title: A retrospective cohort study of the potency of lipid-lowering therapy and race-gender differences in LDL cholesterol control.
Journal: BMC cardiovascular disorders 20110101
Title: Formulation and characterization of lipid-based drug delivery system of raloxifene-microemulsion and self-microemulsifying drug delivery system.
Journal: Journal of pharmacy & bioallied sciences 20110101
Title: The importance of the stem cell marker prominin-1/CD133 in the uptake of transferrin and in iron metabolism in human colon cancer Caco-2 cells.
Journal: PloS one 20110101
Title: Intraperitoneal oxygen/ozone treatment decreases the formation of experimental postsurgical peritoneal adhesions and the levels/activity of the local ubiquitin-proteasome system.
Journal: Mediators of inflammation 20110101
Title: The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1.
Journal: PloS one 20110101
Title: Topical treatment of CHILD nevus and Sjögren-Larsson Syndrome with combined lovastatin and cholesterol.
Journal: European journal of dermatology : EJD 20110101
Title: Predicting P-glycoprotein-mediated drug transport based on support vector machine and three-dimensional crystal structure of P-glycoprotein.
Journal: PloS one 20110101
Title: Effectiveness of Ezetimibe in Reducing the Estimated Risk for Fatal Cardiovascular Events in Hypercholesterolaemic Patients with Inadequate Lipid Control While on Statin Monotherapy as Measured by the SCORE Model.
Journal: Advances in preventive medicine 20110101
Title: Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells.
Journal: Respiratory research 20110101
Title: Challenges associated with tyrosine kinase inhibitor therapy for metastatic thyroid cancer.
Journal: Journal of thyroid research 20110101
Title: Changes in cholesterol homeostasis modify the response of F1B hamsters to dietary very long chain n-3 and n-6 polyunsaturated fatty acids.
Journal: Lipids in health and disease 20110101
Title: L-DOPA-Induced Dyskinesia and Abnormal Signaling in Striatal Medium Spiny Neurons: Focus on Dopamine D1 Receptor-Mediated Transmission.
Journal: Frontiers in behavioral neuroscience 20110101
Title: Rac1-regulated endothelial radiation response stimulates extravasation and metastasis that can be blocked by HMG-CoA reductase inhibitors.
Journal: PloS one 20110101
Title: Optimal production and biochemical properties of a lipase from Candida albicans.
Journal: International journal of molecular sciences 20110101
Title: Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity.
Journal: PloS one 20110101
Title: Predicting in vivo anti-hepatofibrotic drug efficacy based on in vitro high-content analysis.
Journal: PloS one 20110101
Title: Apolipoprotein E mRNA expression in mononuclear cells from normolipidemic and hypercholesterolemic individuals treated with atorvastatin.
Journal: Lipids in health and disease 20110101
Title: Diffuse Idiopathic Skeletal Hyperostosis (DISH)-A Rare Etiology of Dysphagia.
Journal: Clinical medicine insights. Arthritis and musculoskeletal disorders 20110101
Title: Extended release niacin-laropiprant in patients with hypercholesterolemia or mixed dyslipidemias improves clinical parameters.
Journal: Clinical Medicine Insights. Cardiology 20110101
Title: Use of antimony in the treatment of leishmaniasis: current status and future directions.
Journal: Molecular biology international 20110101
Title: Chimeric anti-staphylococcal enterotoxin B antibodies and lovastatin act synergistically to provide in vivo protection against lethal doses of SEB.
Journal: PloS one 20110101
Title: Adaptation to statins restricts human tumour growth in Nude mice.
Journal: BMC cancer 20110101
Title: Regulation of neutrophil survival/apoptosis by Mcl-1.
Journal: TheScientificWorldJournal 20110101
Title: Inhibitory effects of clinical reagents having anti-oxidative activity on transforming growth factor-β1-induced expression of α-smooth muscle actin in human fetal lung fibroblasts.
Journal: The Journal of toxicological sciences 20110101
Title: Ras-ERK Signaling in Behavior: Old Questions and New Perspectives.
Journal: Frontiers in behavioral neuroscience 20110101
Title: P(5A)-type ATPase Cta4p is essential for Ca2+ transport in the endoplasmic reticulum of Schizosaccharomyces pombe.
Journal: PloS one 20110101
Title: Factors Affecting EWS-FLI1 Activity in Ewing's Sarcoma.
Journal: Sarcoma 20110101
Title: Structural basis and kinetics of force-induced conformational changes of an αA domain-containing integrin.
Journal: PloS one 20110101
Title: Interkingdom gene transfer of a hybrid NPS/PKS from bacteria to filamentous Ascomycota.
Journal: PloS one 20110101
Title: Decrease in the production of β-amyloid by berberine inhibition of the expression of β-secretase in HEK293 cells.
Journal: BMC neuroscience 20110101
Title: Statins promote the regression of atherosclerosis via activation of the CCR7-dependent emigration pathway in macrophages.
Journal: PloS one 20110101
Title: Novel mucus-penetrating liposomes as a potential oral drug delivery system: preparation, in vitro characterization, and enhanced cellular uptake.
Journal: International journal of nanomedicine 20110101
Title: Medical angioplasty - hope and expectations: an optimistic overview.
Journal: Journal of family & community medicine 20110101
Title: Assessment of monacolin in the fermented products using Monascus purpureus FTC5391.
Journal: Journal of biomedicine & biotechnology 20110101
Title: Peroxisome Proliferator-Activated Receptor-α Activation Decreases Mean Arterial Pressure, Plasma Interleukin-6, and COX-2 While Increasing Renal CYP4A Expression in an Acute Model of DOCA-Salt Hypertension.
Journal: PPAR research 20110101
Title: Cholesterol, C-Reactive Protein, and Periodontitis: HMG-CoA-Reductase Inhibitors (Statins) as Effect Modifiers.
Journal: ISRN dentistry 20110101
Title: Statin-associated muscular and renal adverse events: data mining of the public version of the FDA adverse event reporting system.
Journal: PloS one 20110101
Title: Differential effects of pravastatin and simvastatin on the growth of tumor cells from different organ sites.
Journal: PloS one 20110101
Title: Preparation and characterization of pioglitazone cyclodextrin inclusion complexes.
Journal: Journal of young pharmacists : JYP 20110101
Title: Critical appraisal of ticagrelor in the management of acute coronary syndrome.
Journal: Therapeutics and clinical risk management 20110101
Title: Two-way pharmacokinetic interaction studies between saxagliptin and cytochrome P450 substrates or inhibitors: simvastatin, diltiazem extended-release, and ketoconazole.
Journal: Clinical pharmacology : advances and applications 20110101
Title: Mthfs is an Essential Gene in Mice and a Component of the Purinosome.
Journal: Frontiers in genetics 20110101
Title: Triterpenoid modulation of IL-17 and Nrf-2 expression ameliorates neuroinflammation and promotes remyelination in autoimmune encephalomyelitis.
Journal: Scientific reports 20110101
Title: Formulation and evaluation of controlled-release tablet of zolpidem tartrate by melt granulation technique.
Journal: ISRN pharmaceutics 20110101
Title: No consensus on definition criteria for stroke registry common data elements.
Journal: Cerebrovascular diseases extra 20110101
Title: Statin Hepatotoxicity: Is it a Real Concern?
Journal: Heart views : the official journal of the Gulf Heart Association 20110101
Title: Statins: past and present.
Journal: Heart views : the official journal of the Gulf Heart Association 20110101
Title: Improved bioavailability through floating microspheres of lovastatin.
Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101
Title: Renoprotective effects of combining ACE inhibitors and statins in experimental diabetic rats.
Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101
Title: Approach to lipid screening as a risk marker for cardiovascular disease in pediatric patients with diabetes.
Journal: Frontiers in endocrinology 20110101
Title: Activation of LDL receptor expression by small RNAs complementary to a noncoding transcript that overlaps the LDLR promoter.
Journal: Chemistry & biology 20101222
Title: Differential interactions between statins and P-glycoprotein: implications for exploiting statins as anticancer agents.
Journal: International journal of cancer 20101215
Title: Membrane raft association of the Vpu protein of human immunodeficiency virus type 1 correlates with enhanced virus release.
Journal: Virology 20101205
Title: Effects of Satureja khuzestanica on Serum Glucose, Lipids and Markers of Oxidative Stress in Patients with Type 2 Diabetes Mellitus: A Double-Blind Randomized Controlled Trial.
Journal: Evidence-based complementary and alternative medicine : eCAM 20101201
Title: Lovastatin overcomes gefitinib resistance in human non-small cell lung cancer cells with K-Ras mutations.
Journal: Investigational new drugs 20101201
Title: Lipophilic statins prevent matrix metalloproteinase-mediated cartilage collagen breakdown by inhibiting protein geranylgeranylation.
Journal: Annals of the rheumatic diseases 20101201
Title: Lovastatin induces neuronal differentiation and apoptosis of embryonal carcinoma and neuroblastoma cells: enhanced differentiation and apoptosis in combination with dbcAMP.
Journal: Molecular and cellular biochemistry 20101201
Title: In vitro evaluation of inhibitory effects of antidiabetic and antihyperlipidemic drugs on human carboxylesterase activities.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Detailed molecular fingerprinting of four new anaplastic thyroid carcinoma cell lines and their use for verification of RhoB as a molecular therapeutic target.
Journal: The Journal of clinical endocrinology and metabolism 20101201
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Engineered polyketide biosynthesis and biocatalysis in Escherichia coli.
Journal: Applied microbiology and biotechnology 20101201
Title: IL-2 costimulation enables statin-mediated activation of human NK cells, preferentially through a mechanism involving CD56+ dendritic cells.
Journal: Cancer research 20101201
Title: Natural variation in Arabidopsis leads to the identification of REME1, a pentatricopeptide repeat-DYW protein controlling the editing of mitochondrial transcripts.
Journal: Plant physiology 20101201
Title: Experimental analysis and modelling of in vitro HUVECs proliferation in the presence of various types of drugs.
Journal: Cell proliferation 20101201
Title: Response surface methodology for lovastatin production by Aspergillus terreus GD13 strain.
Journal: Acta microbiologica et immunologica Hungarica 20101201
Title: d-δ-Tocotrienol-mediated cell cycle arrest and apoptosis in human melanoma cells.
Journal: Anticancer research 20101201
Title: Human hydroxymethylglutaryl-coenzyme A reductase (HMGCR) and statin sensitivity.
Journal: Indian journal of biochemistry & biophysics 20101201
Title: Tumor specific low pH environments enhance the cytotoxicity of lovastatin and cantharidin.
Journal: Cancer letters 20101128
Title: Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion.
Journal: The Journal of biological chemistry 20101126
Title: Synthesis and antihyperlipidemic activity of novel coumarin bisindole derivatives.
Journal: Bioorganic & medicinal chemistry letters 20101115
Title: Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials.
Journal: Lancet (London, England) 20101113
Title: Potent anti-ischaemic effects of statins in chronic stable angina: incremental benefit beyond lipid lowering?
Journal: European heart journal 20101101
Title: Simvastatin and purine analogs have a synergic effect on apoptosis of chronic lymphocytic leukemia cells.
Journal: Annals of hematology 20101101
Title: Prevalence and overlap of different lipid abnormalities in statin-treated patients at high cardiovascular risk in clinical practice in Germany.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20101101
Title: Activation of PPAR-γ and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells.
Journal: Glia 20101101
Title: Molecular cloning and characterization of the global regulator LaeA in Penicillium citrinum.
Journal: Biotechnology letters 20101101
Title: Lovastatin raises serum osteoprotegerin level in people with type 2 diabetic nephropathy.
Journal: Clinical biochemistry 20101101
Title: Effect of fluvastatin, lovastatin, nifedipine and verapamil on the systemic exposure of nateglinide in rabbits.
Journal: Biopharmaceutics & drug disposition 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: The requirement of p53 for maintaining chromosomal stability during tetraploidization.
Journal: Oncotarget 20101101
Title: Marked variability of monacolin levels in commercial red yeast rice products: buyer beware!
Journal: Archives of internal medicine 20101025
Title: Synthesis and biological evaluation of a series of aromatic bisphosphonates.
Journal: Bioorganic & medicinal chemistry 20101015
Title: Accelerated solvent extraction of monacolin K from red yeast rice and purification by high-speed counter-current chromatography.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015
Title: Impact of dietary fat type within the context of altered cholesterol homeostasis on cholesterol and lipoprotein metabolism in the F1B hamster.
Journal: Metabolism: clinical and experimental 20101001
Title: Cholesterol biosynthesis pathway intermediates and inhibitors regulate glucose-stimulated insulin secretion and secretory granule formation in pancreatic beta-cells.
Journal: Endocrinology 20101001
Title: Compromized geranylgeranylation of RhoA and Rac1 in mevalonate kinase deficiency.
Journal: Journal of inherited metabolic disease 20101001
Title: Effects of lovastatin on the pharmacokinetics of nicardipine in rats.
Journal: Biopharmaceutics & drug disposition 20101001
Title: High Lipoprotein(a) Levels are Associated With Long-Term Adverse Outcomes in Acute Myocardial Infarction Patients in High Killip Classes.
Journal: Korean circulation journal 20101001
Title: Are we getting to lipid targets in real life?
Journal: Archives of medical science : AMS 20101001
Title: Discovering drug-drug interactions: a text-mining and reasoning approach based on properties of drug metabolism.
Journal: Bioinformatics (Oxford, England) 20100915
Title: Simvastatin-dependent up-regulation of heme oxygenase-1 via mRNA stabilization in human endothelial cells.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100911
Title: Mevastatin accelerates loss of synaptic proteins and neurite degeneration in aging cortical neurons in a heme-independent manner.
Journal: Neurobiology of aging 20100901
Title: Lipid Lowering Activity of Anthocephalus indicus Root in Hyperlipidemic Rats.
Journal: Evidence-based complementary and alternative medicine : eCAM 20100901
Title: Do statins beneficially or adversely affect glucose homeostasis?
Journal: Current vascular pharmacology 20100901
Title: Profiling induction of cytochrome p450 enzyme activity by statins using a new liquid chromatography-tandem mass spectrometry cocktail assay in human hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20100901
Title: Impact of linoleic acid supplementation on lovastatin production in Aspergillus terreus cultures.
Journal: Applied microbiology and biotechnology 20100901
Title: Biosynthesis of lovastatin and related metabolites formed by fungal iterative PKS enzymes.
Journal: Biopolymers 20100901
Title: Cholesterol depletion affects infectivity and stability of pseudorabies virus.
Journal: Virus research 20100901
Title: Lovastatin inhibits gap junctional communication in cultured aortic smooth muscle cells.
Journal: Journal of cardiovascular pharmacology and therapeutics 20100901
Title: Rosuvastatin, identified from a zebrafish chemical genetic screen for antiangiogenic compounds, suppresses the growth of prostate cancer.
Journal: European urology 20100901
Title: Gluconic acid production by Aspergillus terreus.
Journal: Letters in applied microbiology 20100901
Title: Effectiveness, safety and cost of drug substitution in hypertension.
Journal: British journal of clinical pharmacology 20100901
Title: Molecular insights into amyloid regulation by membrane cholesterol and sphingolipids: common mechanisms in neurodegenerative diseases.
Journal: Expert reviews in molecular medicine 20100901
Title: Conversion investigation for lovastatin and its derivatives by HPLC.
Journal: Journal of chromatographic science 20100901
Title: Persistence with statins and onset of rheumatoid arthritis: a population-based cohort study.
Journal: PLoS medicine 20100901
Title: Ultrasound diagnosis of bilateral quadriceps tendon rupture after statin use.
Journal: The western journal of emergency medicine 20100901
Title: Lovastatin inhibits EGFR dimerization and AKT activation in squamous cell carcinoma cells: potential regulation by targeting rho proteins.
Journal: Oncogene 20100819
Title: [Effects of clinically effective dose of lovastatin on prostate cancer PC3 cells].
Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20100818
Title: Lipid raft modulation inhibits NSCLC cell migration through delocalization of the focal adhesion complex.
Journal: Lung cancer (Amsterdam, Netherlands) 20100801
Title: Ichthyosis in Sjögren-Larsson syndrome reflects defective barrier function due to abnormal lamellar body structure and secretion.
Journal: Archives of dermatological research 20100801
Title: Inhibitory effects of norcantharidin against human lung cancer cell growth and migration.
Journal: Cytotechnology 20100801
Title: Scavenger receptor-B1 and luteal function in mice.
Journal: Journal of lipid research 20100801
Title: Colorimetric determination of simvastatin and lovastatin in pure form and in pharmaceutical formulations.
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100801
Title: Unexpected common mechanistic pathways for embryotoxicity of warfarin and lovastatin.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20100801
Title: Immunomodulatory effects of IFN-beta and lovastatin on immunophenotype of monocyte-derived dendritic cells in multiple sclerosis.
Journal: Archivum immunologiae et therapiae experimentalis 20100801
Title: Effects of fungal statins on high-glucose-induced mouse mesangial cell hypocontractility may involve filamentous actin, t-complex polypeptide 1 subunit beta, and glucose regulated protein 78.
Journal: Translational research : the journal of laboratory and clinical medicine 20100801
Title: Activation of c-Jun N-terminal kinase is required for mevastatin-induced apoptosis of salivary adenoid cystic carcinoma cells.
Journal: Anti-cancer drugs 20100801
Title: Acute activation of eNOS by statins involves scavenger receptor-B1, G protein subunit Gi, phospholipase C and calcium influx.
Journal: British journal of pharmacology 20100801
Title: Lipid rafts are essential for peroxisome biogenesis in HepG2 cells.
Journal: Hepatology (Baltimore, Md.) 20100801
Title: [Effect of lovastatin and rosiglitazone on cholesterol reverse transportation in foam cell].
Journal: Zhonghua nei ke za zhi 20100801
Title: The role of soy in vegetarian diets.
Journal: Nutrients 20100801
Title: Chronic cholesterol depletion using statin impairs the function and dynamics of human serotonin(1A) receptors.
Journal: Biochemistry 20100706
Title: Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20100701
Title: A sustained release of lovastatin from biodegradable, elastomeric polyurethane scaffolds for enhanced bone regeneration.
Journal: Tissue engineering. Part A 20100701
Title: Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009.
Journal: Diabetologia 20100701
Title: Lovastatin induces VSMC differentiation through inhibition of Rheb and mTOR.
Journal: American journal of physiology. Cell physiology 20100701
Title: Variation of herbivore-induced volatile terpenes among Arabidopsis ecotypes depends on allelic differences and subcellular targeting of two terpene synthases, TPS02 and TPS03.
Journal: Plant physiology 20100701
Title: The influence of Sam-Chil-Geun (Panax notoginseng) on the serum lipid levels and inflammations of rats with hyperlipidemia induced by poloxamer-407.
Journal: Yonsei medical journal 20100701
Title: Current and future pharmacological treatment strategies in X-linked adrenoleukodystrophy.
Journal: Brain pathology (Zurich, Switzerland) 20100701
Title: Red yeast rice stimulates osteoblast proliferation and increases alkaline phosphatase activity in MC3T3-E1 cells.
Journal: Nutrition research (New York, N.Y.) 20100701
Title: Influence of drug treatment on glucocorticoid receptor levels in patients with coronary heart disease.
Journal: Chinese medical journal 20100701
Title: A novel statin-mediated 'prenylation block-and-release' assay provides insight into the membrane targeting mechanisms of small GTPases.
Journal: Biochemical and biophysical research communications 20100618
Title: Solanapyrone synthase, a possible Diels-Alderase and iterative type I polyketide synthase encoded in a biosynthetic gene cluster from Alternaria solani.
Journal: Chembiochem : a European journal of chemical biology 20100614
Title: Effect of niacin ER/lovastatin on claudication symptoms in patients with peripheral artery disease.
Journal: Vascular medicine (London, England) 20100601
Title: Inhibition of reactive oxygen species by Lovastatin downregulates vascular endothelial growth factor expression and ameliorates blood-retinal barrier breakdown in db/db mice: role of NADPH oxidase 4.
Journal: Diabetes 20100601
Title: Effects of an anticoagulant and a lipid-lowering agent on the prevention of steroid-induced osteonecrosis in rabbits.
Journal: International journal of experimental pathology 20100601
Title: Severe hypocholesterolaemia is often neglected in haematological malignancies.
Journal: European journal of cancer (Oxford, England : 1990) 20100601
Title: Statin-associated muscle-related adverse effects: a case series of 354 patients.
Journal: Pharmacotherapy 20100601
Title: Lovastatin interacts with natural products to influence cultured hepatocarcinoma cell (hep-g2) growth.
Journal: Journal of the American College of Nutrition 20100601
Title: The role of functional foods, nutraceuticals, and food supplements in intestinal health.
Journal: Nutrients 20100601
Title: Colloid formation by drugs in simulated intestinal fluid.
Journal: Journal of medicinal chemistry 20100527
Title: Lovastatin improves neurological outcome after nucleus basalis magnocellularis lesion in rats.
Journal: Neuroscience 20100519
Title: A historical perspective on the discovery of statins.
Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences 20100511
Title: Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase.
Journal: Journal of cellular and molecular medicine 20100501
Title: Targeted disruption of steroidogenic acute regulatory protein D4 leads to modest weight reduction and minor alterations in lipid metabolism.
Journal: Journal of lipid research 20100501
Title: Lovastatin decreases acute mucosal inflammation via 15-epi-lipoxin A4.
Journal: Mucosal immunology 20100501
Title: Relationships between metabolic syndrome and other baseline factors and the efficacy of ezetimibe/simvastatin and atorvastatin in patients with type 2 diabetes and hypercholesterolemia.
Journal: Diabetes care 20100501
Title: Unraveling polyketide synthesis in members of the genus Aspergillus.
Journal: Applied microbiology and biotechnology 20100501
Title: Soluble epoxide hydrolase in atherosclerosis.
Journal: Current atherosclerosis reports 20100501
Title: HMG-CoA reductase inhibitor lovastatin causes reversible cytoskeleton perturbation by RhoA signalling suppression in peritoneal cell line Met5A.
Journal: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20100501
Title: [Mevastatin inhibits the differentiation of thyroid-associated ophthalmopathy derived orbital preadipocytes].
Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100501
Title: Lipid metabolism and HCV infection.
Journal: Viruses 20100501
Title: Rapid multilabel detection of geranylgeranylated proteins by using bioorthogonal ligation chemistry.
Journal: Chembiochem : a European journal of chemical biology 20100412
Title: Modulation of human T cells signaling transduction by lovastatin.
Journal: International journal of cardiology 20100401
Title: Enhancement of lovastatin production by supplementing polyketide antibiotics to the submerged culture of Aspergillus terreus.
Journal: Applied biochemistry and biotechnology 20100401
Title: Hormone and pharmaceutical regulation of ASP production in 3T3-L1 adipocytes.
Journal: Journal of cellular biochemistry 20100401
Title: Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells.
Journal: Diabetes 20100401
Title: A novel geranylgeranyl transferase inhibitor in combination with lovastatin inhibits proliferation and induces autophagy in STS-26T MPNST cells.
Journal: The Journal of pharmacology and experimental therapeutics 20100401
Title: Effects of mevastatin on grafted bone in MRL/MpJ mice.
Journal: Connective tissue research 20100401
Title: Radioprotectors and mitigators of radiation-induced normal tissue injury.
Journal: The oncologist 20100401
Title: PLoS Computational Biology conference postcards from PSB 2010.
Journal: PLoS computational biology 20100401
Title: A systematic review and meta-analysis on the therapeutic equivalence of statins.
Journal: Journal of clinical pharmacy and therapeutics 20100401
Title: Effects of grape pomace on the antioxidant defense system in diet-induced hypercholesterolemic rabbits.
Journal: Nutrition research and practice 20100401
Title: Lovastatin prevents carcinogenesis in a rat model for liver cancer. Effects of ubiquinone supplementation.
Journal: Anticancer research 20100401
Title: Ochratoxin a: general overview and actual molecular status.
Journal: Toxins 20100401
Title: Pharmacokinetic interaction between oral lovastatin and verapamil in healthy subjects: role of P-glycoprotein inhibition by lovastatin.
Journal: European journal of clinical pharmacology 20100301
Title: Expression, localization, and pharmacological role of Kv7 potassium channels in skeletal muscle proliferation, differentiation, and survival after myotoxic insults.
Journal: The Journal of pharmacology and experimental therapeutics 20100301
Title: BMPER is upregulated by statins and modulates endothelial inflammation by intercellular adhesion molecule-1.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20100301
Title: Effect of statins on the viability of macrophages and smooth muscle cells.
Journal: Journal of cardiovascular pharmacology 20100301
Title: Effects of lipophilic emulsifiers on the oral administration of lovastatin from nanostructured lipid carriers: physicochemical characterization and pharmacokinetics.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20100301
Title: Drug interactions with HMG-CoA reductase inhibitors (statins): the importance of CYP enzymes, transporters and pharmacogenetics.
Journal: Current opinion in investigational drugs (London, England : 2000) 20100301
Title: Role of C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome.
Journal: Current atherosclerosis reports 20100301
Title: [Establishment of a model for evaluating hypolipidemic effect in HepG2 cells].
Journal: Wei sheng yan jiu = Journal of hygiene research 20100301
Title: Substituted benzothiophene or benzofuran derivatives as a novel class of bone morphogenetic protein-2 up-regulators: synthesis, structure-activity relationships, and preventive bone loss efficacies in senescence accelerated mice (SAMP6) and ovariectomized rats.
Journal: Journal of medicinal chemistry 20100225
Title: Red mold rice promotes neuroprotective sAPPalpha secretion instead of Alzheimer's risk factors and amyloid beta expression in hyperlipidemic Abeta40-infused rats.
Journal: Journal of agricultural and food chemistry 20100224
Title: Cholesterol reduction impairs exocytosis of synaptic vesicles.
Journal: Journal of cell science 20100215
Title: Improvement of trochanteric bone quality in an osteoporosis model after short-term treatment with parathyroid hormone: a new mechanical test for trochanteric region of rat femur.
Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20100201
Title: Statins potentiate cytostatic/cytotoxic activity of sorafenib but not sunitinib against tumor cell lines in vitro.
Journal: Cancer letters 20100201
Title: The isoprenoid pathway and transcriptional response to its inhibitors in the yeast Saccharomyces cerevisiae.
Journal: FEMS yeast research 20100201
Title: In vitro interactions between primycin and different statins in their effects against some clinically important fungi.
Journal: Journal of medical microbiology 20100201
Title: Effects of walnut consumption on endothelial function in type 2 diabetic subjects: a randomized controlled crossover trial.
Journal: Diabetes care 20100201
Title: The PPR protein encoded by the LOVASTATIN INSENSITIVE 1 gene is involved in RNA editing at three sites in mitochondria of Arabidopsis thaliana.
Journal: The Plant journal : for cell and molecular biology 20100201
Title: The effect of ethanol on oral cocaine pharmacokinetics reveals an unrecognized class of ethanol-mediated drug interactions.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20100201
Title: Lovastatin-induced cholesterol depletion affects both apical sorting and endocytosis of aquaporin-2 in renal cells.
Journal: American journal of physiology. Renal physiology 20100201
Title: The mitochondrial PPR protein LOVASTATIN INSENSITIVE 1 plays regulatory roles in cytosolic and plastidial isoprenoid biosynthesis through RNA editing.
Journal: The Plant journal : for cell and molecular biology 20100201
Title: Lovastatin ameliorates alpha-synuclein accumulation and oxidation in transgenic mouse models of alpha-synucleinopathies.
Journal: Experimental neurology 20100201
Title: Prediction of cardiovascular event risk reduction from lipid changes associated with high potency dyslipidemia therapy.
Journal: Current medical research and opinion 20100201
Title: Building a tiered approach to in vitro predictive toxicity screening: a focus on assays with in vivo relevance.
Journal: Combinatorial chemistry & high throughput screening 20100201
Title: Measuring hsCRP--an important part of a comprehensive risk profile or a clinically redundant practice?
Journal: PLoS medicine 20100201
Title: Lovastatin inhibits the thrombin-induced loss of barrier integrity in bovine corneal endothelium.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20100201
Title: Effect of preoperative statin therapy on myocardial protection and morbidity endpoints following off-pump coronary bypass surgery in patients with elevated C-reactive protein level.
Journal: Korean journal of anesthesiology 20100201
Title: Lovastatin in X-linked adrenoleukodystrophy.
Journal: The New England journal of medicine 20100121
Title: A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion.
Journal: British journal of cancer 20100119
Title: In vivo evidence of duality effects for lovastatin in a nude mouse cancer model.
Journal: International journal of cancer 20100115
Title: Farnesyl pyrophosphate inhibits epithelialization and wound healing through the glucocorticoid receptor.
Journal: The Journal of biological chemistry 20100115
Title: Identification of the mokH gene encoding transcription factor for the upregulation of monacolin K biosynthesis in Monascus pilosus.
Journal: Journal of agricultural and food chemistry 20100113
Title: Ethanol enhances hepatitis C virus replication through lipid metabolism and elevated NADH/NAD+.
Journal: The Journal of biological chemistry 20100108
Title: Lovastatin inhibits oxidized L-A-phosphatidylcholine B-arachidonoyl-gamma-palmitoyl (ox-PAPC)-stimulated interleukin-8 mRNA and protein synthesis in human aortic endothelial cells by depleting stores of geranylgeranyl pyrophosphate.
Journal: Atherosclerosis 20100101
Title: Development and characterization of a lovastatin-loaded self-microemulsifying drug delivery system.
Journal: Pharmaceutical development and technology 20100101
Title: Biotechnological production and applications of statins.
Journal: Applied microbiology and biotechnology 20100101
Title: A role of nitric oxide in neurite outgrowth of neuroblastoma cells triggered by mevastatin or serum reduction.
Journal: Neuroscience letters 20100101
Title: Drug resistance in visceral leishmaniasis.
Journal: Journal of biomedicine & biotechnology 20100101
Title: Effect of lovastatin on primary prevention of cardiovascular events in mild CKD and kidney function loss: a post hoc analysis of the Air Force/Texas Coronary Atherosclerosis Prevention Study.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20100101
Title: Targeting viral infection by microRNA inhibition.
Journal: Genome biology 20100101
Title: Effects of lovastatin on breast cancer cells: a proteo-metabonomic study.
Journal: Breast cancer research : BCR 20100101
Title: An alternative treatment of hyperlipidemia with red yeast rice: a case report.
Journal: Journal of medical case reports 20100101
Title: Evaluation of a pig femoral head osteonecrosis model.
Journal: Journal of orthopaedic surgery and research 20100101
Title: Current status and future directions in lipid management: emphasizing low-density lipoproteins, high-density lipoproteins, and triglycerides as targets for therapy.
Journal: Vascular health and risk management 20100101
Title: Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin: potential therapeutic relevance.
Journal: BMC cancer 20100101
Title: HMG-CoA reductase inhibitors in kidney transplant recipients receiving tacrolimus: statins not associated with improved patient or graft survival.
Journal: BMC nephrology 20100101
Title: Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer.
Journal: BMC cancer 20100101
Title: Effects of statins on nitric oxide/cGMP signaling in human umbilical vein endothelial cells.
Journal: Pharmacological reports : PR 20100101
Title: Upregulation of geranylgeranyltransferase I in bronchial smooth muscle of mouse experimental asthma: its inhibition by lovastatin.
Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20100101
Title: Simvastatin protects bladder and renal functions following spinal cord injury in rats.
Journal: Journal of inflammation (London, England) 20100101
Title: Statins and cognitive functioning in the elderly: a population-based study.
Journal: Journal of Alzheimer's disease : JAD 20100101
Title: Statins and the squalene synthase inhibitor zaragozic acid stimulate the non-amyloidogenic pathway of amyloid-beta protein precursor processing by suppression of cholesterol synthesis.
Journal: Journal of Alzheimer's disease : JAD 20100101
Title: Metabolic engineering for production of biorenewable fuels and chemicals: contributions of synthetic biology.
Journal: Journal of biomedicine & biotechnology 20100101
Title: High-content, image-based screening for drug targets in yeast.
Journal: PloS one 20100101
Title: Critical appraisal of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia.
Journal: Therapeutics and clinical risk management 20100101
Title: Phenotypic connections in surprising places.
Journal: Genome biology 20100101
Title: Cardiovascular dementia - a different perspective.
Journal: The open biochemistry journal 20100101
Title: Major diet-drug interactions affecting the kinetic characteristics and hypolipidaemic properties of statins.
Journal: Nutricion hospitalaria 20100101
Title: Toxicology and drug delivery by cucurbit[n]uril type molecular containers.
Journal: PloS one 20100101
Title: Treatment with apolipoprotein A-1 mimetic peptide reduces lupus-like manifestations in a murine lupus model of accelerated atherosclerosis.
Journal: Arthritis research & therapy 20100101
Title: A role for the mevalonate pathway in the induction of subtype cross-reactive immunity to influenza A virus by human gammadelta T lymphocytes.
Journal: Cellular immunology 20100101
Title: Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch database.
Journal: BMJ (Clinical research ed.) 20100101
Title: Atorvastatin as a potential anti-malarial drug: in vitro synergy in combinational therapy with quinine against Plasmodium falciparum.
Journal: Malaria journal 20100101
Title: Statin treatment and mortality in bacterial infections--a systematic review and meta-analysis.
Journal: PloS one 20100101
Title: Optimization of the fermentation process of actinomycete strain hhs.015.
Journal: Journal of biomedicine & biotechnology 20100101
Title: New and extended-action treatments in the management of ADHD: a critical appraisal of lisdexamfetamine in adults and children.
Journal: Neuropsychiatric disease and treatment 20100101
Title: The risk for significant creatine kinase elevation with statins.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20100101
Title: Statins in candidemia: clinical outcomes from a matched cohort study.
Journal: BMC infectious diseases 20100101
Title: Dynamics of lamin-A processing following precursor accumulation.
Journal: PloS one 20100101
Title: Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication.
Journal: Molecular systems biology 20100101
Title: Fenofibric acid: a new fibrate approved for use in combination with statin for the treatment of mixed dyslipidemia.
Journal: Vascular health and risk management 20100101
Title: Lovastatin protects against experimental plague in mice.
Journal: PloS one 20100101
Title: Paraoxonase: Its antiatherogenic role in chronic renal failure.
Journal: Indian journal of nephrology 20100101
Title: Cell cycle and anti-estrogen effects synergize to regulate cell proliferation and ER target gene expression.
Journal: PloS one 20100101
Title: Membrane plasmalogen composition and cellular cholesterol regulation: a structure activity study.
Journal: Lipids in health and disease 20100101
Title: Exenatide: a new promising antidiabetic agent.
Journal: Indian journal of pharmaceutical sciences 20100101
Title: [With red rice against cholesterol?].
Journal: Duodecim; laaketieteellinen aikakauskirja 20100101
Title: Characterization of the apoptotic response of human leukemia cells to organosulfur compounds.
Journal: BMC cancer 20100101
Title: Exobiopolymer production of Ophiocordyceps dipterigena BCC 2073: optimization, production in bioreactor and characterization.
Journal: BMC biotechnology 20100101
Title: Osteogenic activity of locally applied small molecule drugs in a rat femur defect model.
Journal: Journal of biomedicine & biotechnology 20100101
Title: Effect of apoA-I on cholesterol release and apoE secretion in human mature adipocytes.
Journal: Lipids in health and disease 20100101
Title: Differences in efficacy and safety of pharmaceutical treatments between men and women: an umbrella review.
Journal: PloS one 20100101
Title: Molecular apocrine differentiation is a common feature of breast cancer in patients with germline PTEN mutations.
Journal: Breast cancer research : BCR 20100101
Title: Volatile profiling reveals intracellular metabolic changes in Aspergillus parasiticus: veA regulates branched chain amino acid and ethanol metabolism.
Journal: BMC biochemistry 20100101
Title: Activating Transcription Factor 3 regulates in part the enhanced tumour cell cytotoxicity of the histone deacetylase inhibitor M344 and cisplatin in combination.
Journal: Cancer cell international 20100101
Title: Lovastatin inhibits VEGFR and AKT activation: synergistic cytotoxicity in combination with VEGFR inhibitors.
Journal: PloS one 20100101
Title: Chicken model of steroid-induced bone marrow adipogenesis using proteome analysis: a preliminary study.
Journal: Proteome science 20100101
Title: Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway.
Journal: Journal of experimental & clinical cancer research : CR 20100101
Title: Analysis of a vascular screening program in a rural community.
Journal: Journal of cardiovascular disease research 20100101
Title: Plant sterols, marine-derived omega-3 fatty acids and other functional ingredients: a new frontier for treating hyperlipidemia.
Journal: Nutrition & metabolism 20100101
Title: Statins and clinical outcome of acute ischemic stroke: a systematic review.
Journal: International archives of medicine 20100101
Title: FasL and FADD delivery by a glioma-specific and cell cycle-dependent HSV-1 amplicon virus enhanced apoptosis in primary human brain tumors.
Journal: Molecular cancer 20100101
Title: Lovastatin inhibits T-cell proliferation while preserving the cytolytic function of EBV, CMV, and MART-1-specific CTLs.
Journal: Journal of immunotherapy (Hagerstown, Md. : 1997) 20100101
Title: Benefits of statin therapy and compliance in high risk cardiovascular patients.
Journal: Vascular health and risk management 20100101
Title: The effects of a commercially available botanical supplement on strength, body composition, power output, and hormonal profiles in resistance-trained males.
Journal: Journal of the International Society of Sports Nutrition 20100101
Title: Expression of human A53T alpha-synuclein in the rat substantia nigra using a novel AAV1/2 vector produces a rapidly evolving pathology with protein aggregation, dystrophic neurite architecture and nigrostriatal degeneration with potential to model the pathology of Parkinson's disease.
Journal: Molecular neurodegeneration 20100101
Title: Drug interaction and pharmacist.
Journal: Journal of young pharmacists : JYP 20100101
Title: A new fluorescence-based method identifies protein phosphatases regulating lipid droplet metabolism.
Journal: PloS one 20100101
Title: A candidate gene association study on muscat flavor in grapevine (Vitis vinifera L.).
Journal: BMC plant biology 20100101
Title: Niacin or ezetimibe for patients with, or at risk of coronary heart disease.
Journal: Clinical Medicine Insights. Cardiology 20100101
Title: The cost effectiveness of statin therapies in Spain in 2010, after the introduction of generics and reference prices.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20100101
Title: Expression of 3-hydroxy-3-methylglutaryl-CoA reductase, p-hydroxybenzoate-m-geranyltransferase and genes of phenylpropanoid pathway exhibits positive correlation with shikonins content in arnebia [Arnebia euchroma (Royle) Johnston].
Journal: BMC molecular biology 20100101
Title: Clinical evaluation of Dyslipidemia among type II diabetic patients at Public hospital Penang, Malaysia.
Journal: International archives of medicine 20100101
Title: [Effect of polymorphisms of cytochrome P450 and apolipoprotein E genes on therapeutic efficacy of statins].
Journal: Kardiologiia 20100101
Title: [Effect of lovastatin on adhesive and aggregation function of platelets in patients with arterial hypertension and dislipidemia].
Journal: Klinicheskaia meditsina 20100101
Title: Synergic effect of eicosapentaenoic acid and lovastatin on gene expression of HMGCoA reductase and LDL receptor in cultured HepG2 cells.
Journal: Lipids in health and disease 20100101
Title: Combination therapy of statin and ezetimibe for the treatment of familial hypercholesterolemia.
Journal: Vascular health and risk management 20100101
Title: Low high-density lipoprotein cholesterol: current status and future strategies for management.
Journal: Vascular health and risk management 20100101
Title: Pitavastatin approved for treatment of primary hypercholesterolemia and combined dyslipidemia.
Journal: Vascular health and risk management 20100101
Title: Use of hamster as a model to study diet-induced atherosclerosis.
Journal: Nutrition & metabolism 20100101
Title: A novel target of action of minocycline in NGF-induced neurite outgrowth in PC12 cells: translation initiation [corrected] factor eIF4AI.
Journal: PloS one 20100101
Title: Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.
Journal: PloS one 20100101
Title: Simvastatin impairs murine melanoma growth.
Journal: Lipids in health and disease 20100101
Title: Tocotrienols inhibit lipopolysaccharide-induced pro-inflammatory cytokines in macrophages of female mice.
Journal: Lipids in health and disease 20100101
Title: Use of the Joint British Society cardiovascular risk calculator before initiating statins for primary prevention in hospital medicine: experience from a large university teaching hospital.
Journal: International journal of general medicine 20100101
Title: Combination of niacin extended-release and simvastatin results in a less atherogenic lipid profile than atorvastatin monotherapy.
Journal: Vascular health and risk management 20100101
Title: Optimal management of familial hypercholesterolemia: treatment and management strategies.
Journal: Vascular health and risk management 20100101
Title: Pilot study: rapidly cycling hypobaric pressure improves pain after 5 days in adiposis dolorosa.
Journal: Journal of pain research 20100101
Title: Statins STAT for (over)ventilated patients?
Journal: Critical care (London, England) 20100101
Title: Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspective.
Journal: Drug design, development and therapy 20100101
Title: Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment.
Journal: The open cardiovascular medicine journal 20100101
Title: Role of bone marrow-derived monocytes/macrophages in the repair of mucosal damage caused by irradiation and/or anticancer drugs in colitis model.
Journal: Mediators of inflammation 20100101
Title: Controversial data on simvastatin in asthma: What about the rat model?
Journal: Journal of asthma and allergy 20100101
Title: Vitamin B12 Deficiency due to Chlorofluorocarbon: A Case Report.
Journal: Case reports in medicine 20100101
Title: Pitavastatin: evidence for its place in treatment of hypercholesterolemia.
Journal: Core evidence 20100101
Title: Lipid Metabolism and Cardiovascular Risk in HIV-1 Infection and HAART: Present and Future Problems.
Journal: Cholesterol 20100101
Title: Randomized Trial of a Pharmacist-Delivered Intervention for Improving Lipid-Lowering Medication Adherence among Patients with Coronary Heart Disease.
Journal: Cholesterol 20100101
Title: [Evidence-based grounds of the efficacy of simvastatin (zocor): 15 years later].
Journal: Terapevticheskii arkhiv 20100101
Title: Rosuvastatin counteracts vessel arterialisation and sinusoid capillarisation, reduces tumour growth, and prolongs survival in murine hepatocellular carcinoma.
Journal: Gastroenterology research and practice 20100101
Title: Functional toxicogenomics: mechanism-centered toxicology.
Journal: International journal of molecular sciences 20100101
Title: Safety and efficacy of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia.
Journal: Drug, healthcare and patient safety 20100101
Title: Screening of nutrient parameters for mevastatin production by Penicillium citrinum MTCC 1256 under submerged fermentation using the Plackett-Burman design.
Journal: Journal of pharmacy & bioallied sciences 20100101
Title: Traditional used Plants against Cognitive Decline and Alzheimer Disease.
Journal: Frontiers in pharmacology 20100101
Title: Policies to enhance prescribing efficiency in europe: findings and future implications.
Journal: Frontiers in pharmacology 20100101
Title: Cytotoxic evaluation of doxorubicin in combination with simvastatin against human cancer cells.
Journal: Research in pharmaceutical sciences 20100101
Title: Long-term treatment of patients with HIV-1: the role of atazanavir.
Journal: HIV/AIDS (Auckland, N.Z.) 20100101
Title: Individualized initiation of statin therapy determined by baseline LDL-C: Are you more likely to achieve goal LDL-C?
Journal: Risk management and healthcare policy 20100101
Title: Comparing the effects of lovastatin and cornus MAS fruit on fibrinogen level in hypercholesterolemic rabbits.
Journal: ARYA atherosclerosis 20100101
Title: Iatrogenic Femoral Artery Pseudoaneurysm (REVIEW OF TREATMENT OPTIONS).
Journal: ARYA atherosclerosis 20100101
Title: Pharmacological management of metabolic syndrome and its lipid complications.
Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101
Title: Operons.
Journal: Cellular and molecular life sciences : CMLS 20091201
Title: Fluvastatin and lovastatin inhibit granulocyte macrophage-colony stimulating factor-stimulated human eosinophil adhesion to inter-cellular adhesion molecule-1 under flow conditions.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20091201
Title: Identification of mokB involved in monacolin K biosynthesis in Monascus pilosus.
Journal: Biotechnology letters 20091201
Title: The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro.
Journal: Bone 20091201
Title: HTS and hit finding in academia--from chemical genomics to drug discovery.
Journal: Drug discovery today 20091201
Title: Geranylgeraniol prevents the cytotoxic effects of mevastatin in THP-1 cells, without decreasing the beneficial effects on cholesterol synthesis.
Journal: British journal of pharmacology 20091201
Title: Blocking LFA-1 activation with lovastatin prevents graft-versus-host disease in mouse bone marrow transplantation.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20091201
Title: Statins: in the beginning.
Journal: The journal of the Royal College of Physicians of Edinburgh 20091201
Title: Cooperation between a coenzyme A-independent stand-alone initiation module and an iterative type I polyketide synthase during synthesis of mycobacterial phenolic glycolipids.
Journal: Journal of the American Chemical Society 20091125
Title: Simvastatin as a potential therapeutic for acute respiratory distress syndrome.
Journal: American journal of respiratory and critical care medicine 20091115
Title: Direct imaging of the disruption of hepatitis C virus replication complexes by inhibitors of lipid metabolism.
Journal: Virology 20091110
Title: Compactin production studies using Penicillium brevicompactum under solid-state fermentation conditions.
Journal: Applied biochemistry and biotechnology 20091101
Title: Aberrant expression of synaptic plasticity-related genes in the NF1+/- mouse hippocampus.
Journal: Journal of neuroscience research 20091101
Title: Regulation of steroid 5-alpha reductase type 2 (Srd5a2) by sterol regulatory element binding proteins and statin.
Journal: Experimental cell research 20091101
Title: Determination of the extent of phosphopantetheinylation of polyketide synthases expressed in Escherichia coli and Saccharomyces cerevisiae.
Journal: Analytical biochemistry 20091101
Title: LFA-1 antagonists as agents limiting human immunodeficiency virus type 1 infection and transmission and potentiating the effect of the fusion inhibitor T-20.
Journal: Antimicrobial agents and chemotherapy 20091101
Title: 7-Difluoromethyl-5,4'-dimethoxygenistein, a novel genistein derivative, has therapeutic effects on atherosclerosis in a rabbit model.
Journal: Journal of cardiovascular pharmacology 20091101
Title: Impact of fixed-dose and multi-pill combination dyslipidemia therapies on medication adherence and the economic burden of sub-optimal adherence.
Journal: Current medical research and opinion 20091101
Title: Novel synthetic inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity that inhibit tumor cell proliferation and are structurally unrelated to existing statins.
Journal: International journal of molecular medicine 20091101
Title: Synergistic effects of lovastatin and celecoxib on caveolin-1 and its down-stream signaling molecules: Implications for colon cancer prevention.
Journal: International journal of oncology 20091101
Title: Quantitative determination of geranyl diphosphate levels in cultured human cells.
Journal: Lipids 20091101
Title: A hidden Markov model for single particle tracks quantifies dynamic interactions between LFA-1 and the actin cytoskeleton.
Journal: PLoS computational biology 20091101
Title: Coronary pressure measurement based decision making for percutaneous coronary intervention.
Journal: Current cardiology reviews 20091101
Title: Complete reconstitution of a highly reducing iterative polyketide synthase.
Journal: Science (New York, N.Y.) 20091023
Title: Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine.
Journal: The Journal of biological chemistry 20091016
Title: Distinct modes of molecular regulation of CCL3 induced calcium flux in monocytic cells.
Journal: Biochemical pharmacology 20091015
Title: Suppression in mevalonate synthesis mediates antitumor effects of combined statin and gamma-tocotrienol treatment.
Journal: Lipids 20091001
Title: Statin therapy and risk of developing type 2 diabetes: a meta-analysis.
Journal: Diabetes care 20091001
Title: Effects of lovastatin on the pharmacokinetics of verapamil and its active metabolite, norverapamil in rats: possible role of P-glycoprotein inhibition by lovastatin.
Journal: Archives of pharmacal research 20091001
Title: Preventing and managing cardiometabolic risk: the logic for intervention.
Journal: International journal of environmental research and public health 20091001
Title: Hypolipidemic effects of Monascus-fermented soybean extracts in rats fed a high-fat and -cholesterol diet.
Journal: Journal of agricultural and food chemistry 20090923
Title: The Monascus metabolite monacolin K reduces tumor progression and metastasis of Lewis lung carcinoma cells.
Journal: Journal of agricultural and food chemistry 20090923
Title: [18F]fluorodeoxyglucose positron emission tomography for lung antiinflammatory response evaluation.
Journal: American journal of respiratory and critical care medicine 20090915
Title: Effects of increasing high-density lipoprotein cholesterol and decreasing low-density lipoprotein cholesterol on the incidence of first acute coronary events (from the Air Force/Texas Coronary Atherosclerosis Prevention Study).
Journal: The American journal of cardiology 20090915
Title: Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090909
Title: Survivin plays as a resistant factor against tamoxifen-induced apoptosis in human breast cancer cells.
Journal: Breast cancer research and treatment 20090901
Title: Statin-induced muscle damage and atrogin-1 induction is the result of a geranylgeranylation defect.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090901
Title: The use of simvastatin in bone regeneration.
Journal: Medicina oral, patologia oral y cirugia bucal 20090901
Title: Lovastatin attenuates ionizing radiation-induced normal tissue damage in vivo.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20090901
Title: Ultrasound assisted ionic liquid dispersive liquid phase extraction of lovastatin and simvastatin: a new pretreatment procedure.
Journal: Journal of separation science 20090901
Title: Inhibition of platelet-rich arterial thrombus in vivo: acute antithrombotic effect of intravenous HMG-CoA reductase therapy.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20090901
Title: Using basic science to design a clinical trial: baseline characteristics of women enrolled in the Kronos Early Estrogen Prevention Study (KEEPS).
Journal: Journal of cardiovascular translational research 20090901
Title: Molecular mechanisms underlying the cholesterol-lowering effect of Ginkgo biloba extract in hepatocytes: a comparative study with lovastatin.
Journal: Acta pharmacologica Sinica 20090901
Title: A simple and sensitive HPLC-UV method for quantitation of lovastatin in human plasma: application to a bioequivalence study.
Journal: Biological & pharmaceutical bulletin 20090901
Title: REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis.
Journal: PLoS biology 20090901
Title: Short term treatment with clarithromycin resulting in colchicine-induced rhabdomyolysis.
Journal: Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20090901
Title: Rhabdomyolysis a result of azithromycin and statins: an unrecognized interaction.
Journal: British journal of clinical pharmacology 20090901
Title: Control of chondrocyte gene expression by actin dynamics: a novel role of cholesterol/Ror-alpha signalling in endochondral bone growth.
Journal: Journal of cellular and molecular medicine 20090901
Title: Cloning and bioinformatic analysis of lovastatin biosynthesis regulatory gene lovE.
Journal: Chinese medical journal 20090805
Title: Synergistic anti-tumor efficacy of lovastatin and protein kinase C-beta inhibitor in hepatocellular carcinoma.
Journal: Cancer chemotherapy and pharmacology 20090801
Title: Red yeast rice fermentation by selected Monascus sp. with deep-red color, lovastatin production but no citrinin, and effect of temperature-shift cultivation on lovastatin production.
Journal: Applied biochemistry and biotechnology 20090801
Title: Different differentiation of stroma cells from patients with osteonecrosis: a pilot study.
Journal: Clinical orthopaedics and related research 20090801
Title: 3-hydroxy 3-methylglutaryl coenzyme A reductase increase is essential for rat muscle differentiation.
Journal: Journal of cellular physiology 20090801
Title: Safety evaluation of Monascus purpureus red mould rice in albino rats.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090801
Title: Myelin proteomics: molecular anatomy of an insulating sheath.
Journal: Molecular neurobiology 20090801
Title: Application of a 3,3-diphenylpentane skeleton as a multi-template for creation of HMG-CoA reductase inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20090801
Title: Synthesis and evaluation of 1-(benzo[b]thiophen-2-yl)ethanone analogues as novel anti-osteoporosis agents acting on BMP-2 promotor.
Journal: Bioorganic & medicinal chemistry letters 20090801
Title: OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism.
Journal: Journal of molecular medicine (Berlin, Germany) 20090801
Title: Autocrine amplification loop in statin-induced apoptosis of human melanoma cells.
Journal: British journal of pharmacology 20090801
Title: High-dose lovastatin for acute ischemic stroke: results of the phase I dose escalation neuroprotection with statin therapy for acute recovery trial (NeuSTART).
Journal: Cerebrovascular diseases (Basel, Switzerland) 20090801
Title: High lovastatin production by Aspergillus terreus in solid-state fermentation on polyurethane foam: an artificial inert support.
Journal: Journal of bioscience and bioengineering 20090801
Title: No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin.
Journal: British journal of clinical pharmacology 20090801
Title: A comparison of pectin, polyphenols, and phytosterols, alone or in combination, to lovastatin for reduction of serum lipids in familial hypercholesterolemic swine.
Journal: Journal of medicinal food 20090801
Title: Inhibitory effect of novel diallyldisulfide analogs on HMG-CoA reductase expression in hypercholesterolemic rats: CREB as a potential upstream target.
Journal: Life sciences 20090731
Title: Mevastatin-induced neurite outgrowth of neuroblastoma cells via activation of EGFR.
Journal: Journal of neuroscience research 20090701
Title: Lovastatin inhibits antigen-induced airway eosinophilia without affecting the production of inflammatory mediators in mice.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090701
Title: Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development.
Journal: Hepatology (Baltimore, Md.) 20090701
Title: Statins inhibit the growth of variant human embryonic stem cells and cancer cells in vitro but not normal human embryonic stem cells.
Journal: British journal of pharmacology 20090701
Title: Comparison of common carotid artery intima-media thickness between Brazilian Euro-descendants and Afro-descendants with atherosclerosis risk factors.
Journal: Clinics (Sao Paulo, Brazil) 20090701
Title: Serum levels of lipoprotein(a) and homocysteine in patients on hemodialysis who take hydroxymethylglutaryl-CoA reductase inhibitors, vitamin B6, and folic acid.
Journal: Iranian journal of kidney diseases 20090701
Title: Effect of precultural and nutritional parameters on compactin production by solid-state fermentation.
Journal: Journal of microbiology and biotechnology 20090701
Title: [Determination of lovastatin and its active metabolites in human plasma with high performance liquid chromatography-tandem mass spectrometry].
Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090701
Title: Effect of folate supplementation on serum homocysteine and plasma total antioxidant capacity in hypercholesterolemic adults under lovastatin treatment: a double-blind randomized controlled clinical trial.
Journal: Archives of medical research 20090701
Title: Acyltransferase mediated polyketide release from a fungal megasynthase.
Journal: Journal of the American Chemical Society 20090624
Title: Cholesterol biosynthesis modulation regulates dengue viral replication.
Journal: Virology 20090620
Title: Systemic administration of HMG-CoA reductase inhibitor protects the blood-retinal barrier and ameliorates retinal inflammation in type 2 diabetes.
Journal: Experimental eye research 20090615
Title: Elevated creatine phosphokinase levels associated with linezolid therapy.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090615
Title: Variability in responsiveness to lovastatin of the primitive CD34+ AML subfraction compared to normal CD34+ cells.
Journal: Annals of hematology 20090601
Title: High-dose lovastatin decreased basal prostacyclin production in cultured endothelial cells.
Journal: Prostaglandins & other lipid mediators 20090601
Title: Increased RhoA and RhoB protein accumulation in cultured human trabecular meshwork cells by lovastatin.
Journal: Investigative ophthalmology & visual science 20090601
Title: MlcR, a zinc cluster activator protein, is able to bind to a single (A/T)CGG site of cognate asymmetric motifs in the ML-236B (compactin) biosynthetic gene cluster.
Journal: Molecular genetics and genomics : MGG 20090601
Title: Improvement of compactin (ML-236B) production by genetic engineering in compactin high-producing Penicillium citrinum.
Journal: Applied microbiology and biotechnology 20090601
Title: Statin-induced liver injury involves cross-talk between cholesterol and selenoprotein biosynthetic pathways.
Journal: Molecular pharmacology 20090601
Title: Combined treatment of gamma-tocotrienol with statins induce mammary tumor cell cycle arrest in G1.
Journal: Experimental biology and medicine (Maywood, N.J.) 20090601
Title: Acute hepatitis caused by a natural lipid-lowering product: when 'alternative' medicine is no 'alternative' at all.
Journal: Journal of hepatology 20090601
Title: [Effect of intensive treatment with atorvastatin versus standard doses of statins on the risk of stroke. A meta-analysis from five randomized trials including 25,709 patients].
Journal: Revista de neurologia 20090601
Title: Impact of apolipoprotein A5 variants on statin treatment efficacy.
Journal: Pharmacogenomics 20090601
Title: Efflux in fungi: la pièce de résistance.
Journal: PLoS pathogens 20090601
Title: Safety and efficacy of red yeast rice (Monascus purpureus) as an alternative therapy for hyperlipidemia.
Journal: P & T : a peer-reviewed journal for formulary management 20090601
Title: Screening and selection of lovastatin hyper-producing mutants of Aspergillus terreus using cyclic mutagenesis.
Journal: Acta microbiologica et immunologica Hungarica 20090601
Title: Adult reversal of cognitive phenotypes in neurodevelopmental disorders.
Journal: Journal of neurodevelopmental disorders 20090601
Title: Human caspase 7 is positively controlled by SREBP-1 and SREBP-2.
Journal: The Biochemical journal 20090527
Title: Comparison of UV and charged aerosol detection approach in pharmaceutical analysis of statins.
Journal: Talanta 20090515
Title: Desmosterol can replace cholesterol in sustaining cell proliferation and regulating the SREBP pathway in a sterol-Delta24-reductase-deficient cell line.
Journal: The Biochemical journal 20090513
Title: How essential is cholesterol?
Journal: The Biochemical journal 20090513
Title: Effects of acid and lactone forms of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on the induction of MDR1 expression and function in LS180 cells.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090512
Title: Quantitative measures of femoral fracture repair in rats derived by micro-computed tomography.
Journal: Journal of biomechanics 20090511
Title: Statins induce apoptosis in ovarian cancer cells through activation of JNK and enhancement of Bim expression.
Journal: Cancer chemotherapy and pharmacology 20090501
Title: Induction of iodide uptake in transformed thyrocytes: a compound screening in cell lines.
Journal: European journal of nuclear medicine and molecular imaging 20090501
Title: Digoxin and ouabain increase the synthesis of cholesterol in human liver cells.
Journal: Cellular and molecular life sciences : CMLS 20090501
Title: d-δ-Tocotrienol-mediated suppression of the proliferation of human PANC-1, MIA PaCa-2, and BxPC-3 pancreatic carcinoma cells.
Journal: Pancreas 20090501
Title: Simvastatin and lovastatin inhibit breast cell invasion induced by H-Ras.
Journal: Oncology reports 20090501
Title: Complete blockage of the mevalonate pathway results in male gametophyte lethality.
Journal: Journal of experimental botany 20090501
Title: The YTA7 gene is involved in the regulation of the isoprenoid pathway in the yeast Saccharomyces cerevisiae.
Journal: FEMS yeast research 20090501
Title: Lovastatin restores the function of endothelial progenitor cells damaged by oxLDL.
Journal: Acta pharmacologica Sinica 20090501
Title: Physiological, morphological and kinetic aspects of lovastatin biosynthesis by Aspergillus terreus.
Journal: Biotechnology journal 20090501
Title: Managing toxicities and optimal dosing of targeted drugs in advanced kidney cancer.
Journal: Current oncology (Toronto, Ont.) 20090501
Title: Asymmetric dimethylarginine (ADMA) and endothelial dysfunction: implications for atherogenesis.
Journal: Clinics (Sao Paulo, Brazil) 20090501
Title: Trypanosoma cruzi: participation of cholesterol and placental alkaline phosphatase in the host cell invasion.
Journal: Experimental parasitology 20090501
Title: Heart Disease in Patients with HIV/AIDS-An Emerging Clinical Problem.
Journal: Current cardiology reviews 20090501
Title: The ginsenoside-Rb2 lowers cholesterol and triacylglycerol levels in 3T3-L1 adipocytes cultured under high cholesterol or fatty acids conditions.
Journal: BMB reports 20090430
Title: Efficient biotransformations using Escherichia coli with tolC acrAB mutations expressing cytochrome P450 genes.
Journal: Bioscience, biotechnology, and biochemistry 20090423
Title: Statins for the prevention of dementia.
Journal: The Cochrane database of systematic reviews 20090415
Title: The g.-762T>C polymorphism of the NPC1L1 gene is common in Chinese and contributes to a higher promoter activity and higher serum cholesterol levels.
Journal: Journal of human genetics 20090401
Title: AMP-activated protein kinase pathway: a potential therapeutic target in cardiometabolic disease.
Journal: Clinical science (London, England : 1979) 20090401
Title: A platform to standardize, store, and visualize proteomics experimental data.
Journal: Acta biochimica et biophysica Sinica 20090401
Title: Towards prediction of metabolic products of polyketide synthases: an in silico analysis.
Journal: PLoS computational biology 20090401
Title: Modified local straight-line screening to detect synthetic drugs in adulterated herbal medicines.
Journal: Applied spectroscopy 20090401
Title: C-reactive protein level following treatment and withdrawal of lovastatin in diabetic nephropathy.
Journal: Iranian journal of kidney diseases 20090401
Title: HIV entry in macrophages is dependent on intact lipid rafts.
Journal: Virology 20090330
Title: Lovastatin induces the formation of abnormal myelin-like membrane sheets in primary oligodendrocytes.
Journal: Glia 20090301
Title: Lovastatin potentiates the antidepressant efficacy of fluoxetine in rats.
Journal: Pharmacology, biochemistry, and behavior 20090301
Title: Effect of Curcuma kwangsiensis polysaccharides on blood lipid profiles and oxidative stress in high-fat rats.
Journal: International journal of biological macromolecules 20090301
Title: Molecular beacons can assess changes in expression and 3'-polyadenylation of human eNOS mRNA.
Journal: American journal of physiology. Cell physiology 20090301
Title: Effects of rutin on lipid profile in hypercholesterolaemic rats.
Journal: Basic & clinical pharmacology & toxicology 20090301
Title: Rhabdomyolysis caused by a potential sitagliptin-lovastatin interaction.
Journal: Pharmacotherapy 20090301
Title: Cholesterol-dependent anaplasma phagocytophilum exploits the low-density lipoprotein uptake pathway.
Journal: PLoS pathogens 20090301
Title: Strategies for blocking the fibrogenic actions of connective tissue growth factor (CCN2): From pharmacological inhibition in vitro to targeted siRNA therapy in vivo.
Journal: Journal of cell communication and signaling 20090301
Title: The carotenogenesis pathway via the isoprenoid-beta-carotene interference approach in a new strain of Dunaliella salina isolated from Baja California Mexico.
Journal: Marine drugs 20090301
Title: Mevinolin enhances osteogenic genes (ALP, type I collagen and osteocalcin), CD44, CD47 and CD51 expression during osteogenic differentiation.
Journal: Life sciences 20090227
Title: Oxysterol activation of phosphatidylcholine synthesis involves CTP:phosphocholine cytidylyltransferase alpha translocation to the nuclear envelope.
Journal: The Biochemical journal 20090215
Title: [Statin therapy and muscle disorders].
Journal: Orvosi hetilap 20090208
Title: [Comment from the lipidologic viewpoint].
Journal: Praxis 20090204
Title: Enhancement of drug solubility in supramolecular and colloidal systems.
Journal: Journal of pharmaceutical sciences 20090201
Title: Mevastatin reduces cartilage degradation in rabbit experimental osteoarthritis through inhibition of synovial inflammation.
Journal: Osteoarthritis and cartilage 20090201
Title: Differential influence of different dietary fatty acids on very low-density lipoprotein secretion when delivered to hepatocytes in chylomicron remnants.
Journal: Metabolism: clinical and experimental 20090201
Title: Should high creatine kinase discourage the initiation or continuance of statins for the treatment of hypercholesterolemia?
Journal: Metabolism: clinical and experimental 20090201
Title: Hematologic parameters, atherosclerotic progression, and prognosis in patients with previous coronary artery bypass grafting (from the Post CABG Trial).
Journal: The American journal of cardiology 20090201
Title: Lack of efficacy of the statins atorvastatin and lovastatin in rodent mammary carcinogenesis.
Journal: Cancer prevention research (Philadelphia, Pa.) 20090201
Title: Co-medication of statins and CYP3A4 inhibitors before and after introduction of new reimbursement policy.
Journal: British journal of clinical pharmacology 20090201
Title: The relationship between reduction in low-density lipoprotein cholesterol by statins and reduction in risk of cardiovascular outcomes: an updated meta-analysis.
Journal: Clinical therapeutics 20090201
Title: [Local straight line screening method for the detection of Chinese proprietary medicines containing undeclared prescription drugs].
Journal: Guang pu xue yu guang pu fen xi = Guang pu 20090201
Title: The effect of dyslipidemic drugs on mortality: A meta-analysis.
Journal: Indian journal of pharmacology 20090201
Title: Combination therapy of lovastatin and rolipram provides neuroprotection and promotes neurorepair in inflammatory demyelination model of multiple sclerosis.
Journal: Glia 20090115
Title: Cloning of the Rhizomucor miehei 3-hydroxy-3-methylglutaryl-coenzyme A reductase gene and its heterologous expression in Mucor circinelloides.
Journal: Antonie van Leeuwenhoek 20090101
Title: Aspergillus westerdijkiae polyketide synthase gene 'aoks1' is involved in the biosynthesis of ochratoxin A.
Journal: Fungal genetics and biology : FG & B 20090101
Title: Does nicotinic acid (niacin) lower blood pressure?
Journal: International journal of clinical practice 20090101
Title: Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis.
Journal: Bioorganic & medicinal chemistry 20090101
Title: Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus.
Journal: BMC chemical biology 20090101
Title: The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression.
Journal: PloS one 20090101
Title: Survey of physician knowledge regarding antiretroviral medications in hospitalized HIV-infected patients.
Journal: Journal of the International AIDS Society 20090101
Title: Neural differentiation potential of human bone marrow-derived mesenchymal stromal cells: misleading marker gene expression.
Journal: BMC neuroscience 20090101
Title: Effects of statins on the secretion of human serum albumin in cultured HepG2 cells.
Journal: Journal of biomedical science 20090101
Title: Campylobacter jejuni induces transcellular translocation of commensal bacteria via lipid rafts.
Journal: Gut pathogens 20090101
Title: Fungal type I polyketide synthases.
Journal: Methods in enzymology 20090101
Title: Neuroprotective effects of statins in an in vitro model of Alzheimer's disease.
Journal: Journal of Alzheimer's disease : JAD 20090101
Title: Pretreatment with lovastatin prevents N-methyl-D-aspartate-induced neurodegeneration in the magnocellular nucleus basalis and behavioral dysfunction.
Journal: Journal of Alzheimer's disease : JAD 20090101
Title: Chapter 2. From microbial products to novel drugs that target a multitude of disease indications.
Journal: Methods in enzymology 20090101
Title: The influence of lovastatin on thrombomodulin gene expression in vascular endothelial cells--in vitro study.
Journal: Folia histochemica et cytobiologica 20090101
Title: Ten-Year Survival in 75-Year-Old Men and Women: Predictive Ability of Total Cholesterol, HDL-C, and LDL-C.
Journal: Current gerontology and geriatrics research 20090101
Title: Role of atazanavir in the treatment of HIV infection.
Journal: Therapeutics and clinical risk management 20090101
Title: Efficacy and safety of rosuvastatin in the management of dyslipidemia.
Journal: Vascular health and risk management 20090101
Title: Prevention of atherosclerosis in patients living with HIV.
Journal: Vascular health and risk management 20090101
Title: Management of complex lipid abnormalities with a fixed dose combination of simvastatin and extended release niacin.
Journal: Vascular health and risk management 20090101
Title: Dyslipidemia treatment of patients with diabetes mellitus in a US managed care plan: a retrospective database analysis.
Journal: Cardiovascular diabetology 20090101
Title: Pharmacological Treatment of Alzheimer's Disease: Is it Progressing Adequately?
Journal: The open neurology journal 20090101
Title: Efficacy, effectiveness and real life goal attainment of statins in managing cardiovascular risk.
Journal: Vascular health and risk management 20090101
Title: Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors.
Journal: Vascular health and risk management 20090101
Title: Impact of statins and ACE inhibitors on mortality after COPD exacerbations.
Journal: Respiratory research 20090101
Title: SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis.
Journal: PloS one 20090101
Title: Lovastatin enhances the genotoxicity of doxorubicin in Chinese hamster V79 cells via noncovalent DNA binding.
Journal: Drug and chemical toxicology 20090101
Title: The biosynthesis and accumulation of beta-carotene in Dunaliella salina proceed via the glyceraldehyde 3-phosphate/pyruvate pathway.
Journal: Natural product research 20090101
Title: Statin use and risk of community acquired pneumonia in older people: population based case-control study.
Journal: BMJ (Clinical research ed.) 20090101
Title: Antiretroviral effect of lovastatin on HIV-1-infected individuals without highly active antiretroviral therapy (The LIVE study): a phase-II randomized clinical trial.
Journal: Trials 20090101
Title: Effect of HMG-CoA reductase inhibitors on activation of human gammadeltaT cells induced by Mycobacterium tuberculosis antigens.
Journal: Immunopharmacology and immunotoxicology 20090101
Title: Postulated vasoactive neuropeptide immunopathology affecting the blood-brain/blood-spinal barrier in certain neuropsychiatric fatigue-related conditions: A role for phosphodiesterase inhibitors in treatment?
Journal: Neuropsychiatric disease and treatment 20090101
Title: A novel flow cytometric high throughput assay for a systematic study on molecular mechanisms underlying T cell receptor-mediated integrin activation.
Journal: PloS one 20090101
Title: The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials.
Journal: BMJ (Clinical research ed.) 20090101
Title: Leptin stimulated C-reactive protein production by human coronary artery endothelial cells.
Journal: Journal of vascular research 20090101
Title: Substance P scavenger enhances antioxidant defenses and prevents prothrombotic effects on the rat lung after acute exposure to oil smoke.
Journal: Journal of biomedical science 20090101
Title: Associations between statins and COPD: a systematic review.
Journal: BMC pulmonary medicine 20090101
Title: Statin-induced calcification in human mesenchymal stem cells is cell death related.
Journal: Journal of cellular and molecular medicine 20090101
Title: Regulation of bile acid and cholesterol metabolism by PPARs.
Journal: PPAR research 20090101
Title: New options in the treatment of lipid disorders in HIV-infected patients.
Journal: The open AIDS journal 20090101
Title: Characteristics, management and attainment of lipid target levels in diabetic and cardiac patients enrolled in Disease Management Program versus those in routine care: LUTZ registry.
Journal: BMC public health 20090101
Title: Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs.
Journal: Interdisciplinary perspectives on infectious diseases 20090101
Title: Managing treatment-experienced pediatric and adolescent HIV patients: role of darunavir.
Journal: Therapeutics and clinical risk management 20090101
Title: Utilization of genomic signatures to identify phenotype-specific drugs.
Journal: PloS one 20090101
Title: Myopathy with concurrent tadalafil and simvastatin.
Journal: Case reports in medicine 20090101
Title: Magnetic resonance imaging of the natural history of in situ mammary neoplasia in transgenic mice: a pilot study.
Journal: Breast cancer research : BCR 20090101
Title: Management of avascular necrosis of femoral head at pre-collapse stage.
Journal: Indian journal of orthopaedics 20090101
Title: Effects of lovastatin and pentoxyphyllin in nonalcoholic steatohepatitis.
Journal: Hepato-gastroenterology 20090101
Title: Decreased ubiquinone availability and impaired mitochondrial cytochrome oxidase activity associated with statin treatment.
Journal: Toxicology mechanisms and methods 20090101
Title: Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action.
Journal: Molecular cancer 20090101
Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.
Journal: PloS one 20090101
Title: [Statins in practice of the vascular surgeon and cardiologist].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20090101
Title: Thinking beyond low-density lipoprotein cholesterol: strategies to further reduce cardiovascular risk.
Journal: Vascular health and risk management 20090101
Title: Apoptosis of lens epithelial cells induced by high concentration of glucose is associated with a decrease in caveolin-1 levels.
Journal: Molecular vision 20090101
Title: A 60-year-old man with chronic renal failure and a costal mass: a case report and review of the literature.
Journal: Journal of medical case reports 20090101
Title: Pleiotropic vasoprotective effects of statins: the chicken or the egg?
Journal: Drug design, development and therapy 20090101
Title: Increased frequency and nocturia in a middle aged male may not always be due to Benign Prostatic Hypertrophy (BPH): a case report.
Journal: Cases journal 20090101
Title: Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.
Journal: Lipids in health and disease 20090101
Title: Prediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profiles.
Journal: PloS one 20090101
Title: Influenza morbidity and mortality in elderly patients receiving statins: a cohort study.
Journal: PloS one 20090101
Title: Management of dyslipidemia in children.
Journal: Diabetology & metabolic syndrome 20090101
Title: [Achievement of blood lipid target levels with Ezetimibe/Simvastatin in patients with atherosclerosis and/or diabetes mellitus--an Austrian observational study].
Journal: Wiener medizinische Wochenschrift (1946) 20090101
Title: Fatal hemopericardial tamponade due to primary pericardial mesothelioma: a case report.
Journal: Diagnostic pathology 20090101
Title: Aurora-A overexpression enhances cell-aggregation of Ha-ras transformants through the MEK/ERK signaling pathway.
Journal: BMC cancer 20090101
Title: Model system for the analysis of cell surface expression of human ABCA1.
Journal: BMC cell biology 20090101
Title: SP-D counteracts GM-CSF-mediated increase of granuloma formation by alveolar macrophages in lysinuric protein intolerance.
Journal: Orphanet journal of rare diseases 20090101
Title: The JUPITER and AURORA clinical trials for rosuvastatin in special primary prevention populations: perspectives, outcomes, and consequences.
Journal: Vascular health and risk management 20090101
Title: Dermatomyositis presenting with rhabdomyolysis and acute renal failure; an uncommon manifestation.
Journal: Annals of Indian Academy of Neurology 20090101
Title: Lipid abnormalities in streptozotocin-diabetes: Amelioration by Morus indica L. cv Suguna leaves.
Journal: International journal of diabetes in developing countries 20090101
Title: Increased frequency and nocturia in a middle aged male may not always be due to benign prostatic hypertrophy: a case report.
Journal: Cases journal 20090101
Title: Lovastatin and fluvastatin reduce viremia and the pro-inflammatory cytokines in the patients with chronic hepatitis C.
Journal: Hepato-gastroenterology 20090101
Title: Acute coronary syndrome in pregnancy.
Journal: Clinical medicine. Cardiology 20090101
Title: Targeted therapy in the treatment of malignant gliomas.
Journal: OncoTargets and therapy 20090101
Title: Epidemiologic characteristics and risk factors for renal cell cancer.
Journal: Clinical epidemiology 20090101
Title: Raising HDL cholesterol in women.
Journal: International journal of women's health 20090101
Title: Improving glycemic and cholesterol control through an integrated approach incorporating colesevelam - a clinical perspective.
Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20090101
Title: Enhanced cytostatic activity of statins in mouse mammary carcinoma cells overexpressing β2-chimaerin.
Journal: Molecular medicine reports 20090101
Title: Long-term use of rosuvastatin: a critical risk benefit appraisal and comparison with other antihyperlipidemics.
Journal: Drug, healthcare and patient safety 20090101
Title: Reconstruction of a bacterial isoprenoid biosynthetic pathway in Saccharomyces cerevisiae.
Journal: FEBS letters 20081210
Title: Berberine decreases PCSK9 expression in HepG2 cells.
Journal: Atherosclerosis 20081201
Title: Statin cost-effectiveness comparisons using real-world effectiveness data: formulary implications.
Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20081201
Title: Lovastatin inhibits adipogenesis and prevents osteonecrosis in steroid-treated rabbits.
Journal: Joint, bone, spine : revue du rhumatisme 20081201
Title: Actin cytoskeleton remodeling governs aquaporin-4 localization in astrocytes.
Journal: Glia 20081201
Title: Interaction between statins and clopidogrel: is there anything clinically relevant?
Journal: QJM : monthly journal of the Association of Physicians 20081201
Title: Combined medication of lovastatin with rolipram suppresses severity of experimental autoimmune encephalomyelitis.
Journal: Experimental neurology 20081201
Title: Lovastatin induces apoptosis of k-ras-transformed thyroid cells via inhibition of ras farnesylation and by modulating redox state.
Journal: Journal of molecular medicine (Berlin, Germany) 20081201
Title: Comparative evaluation of the hypolipidemic effects of coconut water and lovastatin in rats fed fat-cholesterol enriched diet.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081201
Title: Molecular characterization of the Aspergillus fumigatus NCS-1 homologue, NcsA.
Journal: Molecular genetics and genomics : MGG 20081201
Title: Myotoxicity of lipid-lowering agents in a teenager with MELAS mutation.
Journal: Pediatric neurology 20081201
Title: Overexpression of RhoA enhances peritoneal dissemination: RhoA suppression with Lovastatin may be useful for ovarian cancer.
Journal: Cancer science 20081201
Title: Chinese red yeast rice versus lovastatin effects on prostate cancer cells with and without androgen receptor overexpression.
Journal: Journal of medicinal food 20081201
Title: Anti-hyperlipidemic effect of an edible brown algae, Ecklonia stolonifera, and its constituents on poloxamer 407-induced hyperlipidemic and cholesterol-fed rats.
Journal: Archives of pharmacal research 20081201
Title: Solubility enhancement of lovastatin by modified locust bean gum using solid dispersion techniques.
Journal: AAPS PharmSciTech 20081201
Title: Bama miniature pigs (Sus scrofa domestica) as a model for drug evaluation for humans: comparison of in vitro metabolism and in vivo pharmacokinetics of lovastatin.
Journal: Comparative medicine 20081201
Title: Fifth International Workshop on the CCN Family of Genes: Abstracts and Posters October 18-22, 2008.
Journal: Journal of cell communication and signaling 20081201
Title: Report on the fifth international workshop on the CCN family of genes.
Journal: Journal of cell communication and signaling 20081201
Title: Tolerability and effects on lipids of ezetimibe coadministered with pravastatin or simvastatin for twelve months: results from two open-label extension studies in hypercholesterolemic patients.
Journal: Clinical therapeutics 20081201
Title: [Effects of gamma linolenic acid on atherosclerosis induced by cholesterol-rich diet in rats].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081201
Title: Systems biology: a therapeutic target for tumor therapy.
Journal: Cancer microenvironment : official journal of the International Cancer Microenvironment Society 20081201
Title: An integral approach to the etiopathogenesis of human neurodegenerative diseases (HNDDs) and cancer. Possible therapeutic consequences within the frame of the trophic factor withdrawal syndrome (TFWS).
Journal: Neuropsychiatric disease and treatment 20081201
Title: Renin inhibition with aliskiren in hypertension: focus on aliskiren/hydrochlorothiazide combination therapy.
Journal: Vascular health and risk management 20081201
Title: Ranpirnase and its potential for the treatment of unresectable malignant mesothelioma.
Journal: Biologics : targets & therapy 20081201
Title: Concomitant use of statins and CYP3A4 inhibitors in administrative claims and electronic medical records databases.
Journal: Journal of clinical lipidology 20081201
Title: Primary prevention of cardiovascular mortality and events with statin treatments: a network meta-analysis involving more than 65,000 patients.
Journal: Journal of the American College of Cardiology 20081125
Title: The influence of statin medications on prostate-specific antigen levels.
Journal: Journal of the National Cancer Institute 20081105
Title: SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice.
Journal: The Journal of clinical investigation 20081103
Title: Transdermal lovastatin enhances fracture repair in rats.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20081101
Title: Statin suppresses apoptosis in osteoblastic cells: role of transforming growth factor-beta-Smad3 pathway.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20081101
Title: Impact of adherence to statins on chronic heart failure in primary prevention.
Journal: British journal of clinical pharmacology 20081101
Title: Spatial and temporal analysis of pharmaceutical concentrations in the upper Tennessee River basin.
Journal: Chemosphere 20081101
Title: Red mold rice prevents the development of obesity, dyslipidemia and hyperinsulinemia induced by high-fat diet.
Journal: International journal of obesity (2005) 20081101
Title: An evaluation of a data mining signal for amyotrophic lateral sclerosis and statins detected in FDA's spontaneous adverse event reporting system.
Journal: Pharmacoepidemiology and drug safety 20081101
Title: Pleiotropic effect of lovastatin, with and without cholestyramine, in the post coronary artery bypass graft (Post CABG) trial.
Journal: The American journal of cardiology 20081015
Title: Lovastatin enhances gefitinib activity in glioblastoma cells irrespective of EGFRvIII and PTEN status.
Journal: Journal of neuro-oncology 20081001
Title: Lovastatin, but not pravastatin, limits in vitro infection due to Coxiella burnetii.
Journal: The Journal of antimicrobial chemotherapy 20081001
Title: Potent inhibition of cicatricial contraction in proliferative vitreoretinal diseases by statins.
Journal: Diabetes 20081001
Title: AMP-activated protein kinase promotes the differentiation of endothelial progenitor cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20081001
Title: Statins limit Rickettsia conorii infection in cells.
Journal: International journal of antimicrobial agents 20081001
Title: A combination of proteasome inhibitors and antibiotics prevents lethality in a septic shock model.
Journal: Innate immunity 20081001
Title: A gift from nature: the birth of the statins.
Journal: Nature medicine 20081001
Title: Grapefruit juice-drug interaction studies as a method to assess the extent of intestinal availability: utility and limitations.
Journal: Current drug metabolism 20081001
Title: Renal failure and rhabdomyolysis associated with sitagliptin and simvastatin use.
Journal: Diabetic medicine : a journal of the British Diabetic Association 20081001
Title: Excess coronary artery disease risk in South Asian immigrants: can dysfunctional high-density lipoprotein explain increased risk?
Journal: Vascular health and risk management 20081001
Title: The renin angiotensin system in the development of cardiovascular disease: role of aliskiren in risk reduction.
Journal: Vascular health and risk management 20081001
Title: Frequency of secondary dyslipidemia in obese children.
Journal: Vascular health and risk management 20081001
Title: Miscellaneous.
Journal: Indian journal of pharmacology 20081001
Title: Autonomic nervous system and cardiovascular system.
Journal: Indian journal of pharmacology 20081001
Title: Lovastatin inhibits TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts.
Journal: Investigative ophthalmology & visual science 20080901
Title: Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention.
Journal: International journal of cancer 20080901
Title: Utility of a novel Oatp1b2 knockout mouse model for evaluating the role of Oatp1b2 in the hepatic uptake of model compounds.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080901
Title: Extended-release niacin alters the metabolism of plasma apolipoprotein (Apo) A-I and ApoB-containing lipoproteins.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20080901
Title: Metabolically favorable remodeling of human adipose tissue by human adenovirus type 36.
Journal: Diabetes 20080901
Title: Identification of the specific sequence recognized by Penicillium citrinum MlcR, a GAL4-type transcriptional activator of ML-236B (compactin) biosynthetic genes.
Journal: Fungal genetics and biology : FG & B 20080901
Title: BRCA1 overexpression sensitizes cancer cells to lovastatin via regulation of cyclin D1-CDK4-p21WAF1/CIP1 pathway: analyses using a breast cancer cell line and tumoral xenograft model.
Journal: International journal of oncology 20080901
Title: Statins induce regulatory T cell recruitment via a CCL1 dependent pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20080901
Title: Therapy of X-linked adrenoleukodystrophy.
Journal: Expert review of neurotherapeutics 20080901
Title: Lipid lowering effect of antioxidant alpha-lipoic Acid in experimental atherosclerosis.
Journal: Journal of clinical biochemistry and nutrition 20080901
Title: HIV infection in the elderly.
Journal: Clinical interventions in aging 20080901
Title: Study of the intima-media thickening in carotid arteries of healthy elderly with high blood pressure and elderly with high blood pressure and dyslipidemia.
Journal: Clinical interventions in aging 20080901
Title: Can HMG Co-A reductase inhibitors ('statins') slow the progression of age-related macular degeneration? The age-related maculopathy statin study (ARMSS).
Journal: Clinical interventions in aging 20080901
Title: Targeted magnetic iron oxide nanoparticles for tumor imaging and therapy.
Journal: International journal of nanomedicine 20080901
Title: The relationship between obesity and atherosclerotic progression and prognosis among patients with coronary artery bypass grafts the effect of aggressive statin therapy.
Journal: Journal of the American College of Cardiology 20080819
Title: Mevinolin, citrinin and pigments of adlay angkak fermented by Monascus sp.
Journal: International journal of food microbiology 20080815
Title: Alkamides from the fruits of Piper longum and Piper nigrum displaying potent cell adhesion inhibition.
Journal: Bioorganic & medicinal chemistry letters 20080815
Title: Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death.
Journal: Neuroscience letters 20080808
Title: Detection of Lipitor counterfeits: a comparison of NIR and Raman spectroscopy in combination with chemometrics.
Journal: Journal of pharmaceutical and biomedical analysis 20080805
Title: Functional coupling of Gs and CFTR is independent of their association with lipid rafts in epithelial cells.
Journal: Pflugers Archiv : European journal of physiology 20080801
Title: Cholesterol potentiates beta-amyloid-induced toxicity in human neuroblastoma cells: involvement of oxidative stress.
Journal: Neurochemical research 20080801
Title: Effect of APOE genotype on lipid levels in patients with coronary heart disease during a 3-week inpatient rehabilitation program.
Journal: Clinical pharmacology and therapeutics 20080801
Title: Lovastatin effect in rat neuroblasts of the CNS: inhibition of cap-dependent translation.
Journal: Journal of neurochemistry 20080801
Title: Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin.
Journal: Journal of neurochemistry 20080801
Title: Effects of statins on high-density lipoproteins: a potential contribution to cardiovascular benefit.
Journal: Cardiovascular drugs and therapy 20080801
Title: Subclinical atherosclerosis: what it is, what it means and what we can do about it.
Journal: International journal of clinical practice 20080801
Title: Synthesis, DNA binding, and cytotoxic evaluation of new analogs of diallyldisulfide, an active principle of garlic.
Journal: Bioorganic & medicinal chemistry 20080801
Title: Lipophilicity and cardiovascular outcome in patients with CHF.
Journal: American heart journal 20080801
Title: Redispersible, dry emulsion of lovastatin protects against intestinal metabolism and improves bioavailability.
Journal: Acta pharmacologica Sinica 20080801
Title: Synchronization of the cell cycle using lovastatin.
Journal: Cell cycle (Georgetown, Tex.) 20080801
Title: The Neuroprotection with Statin Therapy for Acute Recovery Trial (NeuSTART): an adaptive design phase I dose-escalation study of high-dose lovastatin in acute ischemic stroke.
Journal: International journal of stroke : official journal of the International Stroke Society 20080801
Title: A practical protocol to measure common carotid artery intima-media thickness.
Journal: Clinics (Sao Paulo, Brazil) 20080801
Title: Oxamniquine, praziquantel and lovastatin association in the experimental Schistosomiasis mansoni.
Journal: Memorias do Instituto Oswaldo Cruz 20080801
Title: [Lovastatin protects mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis through activation of PI3K/Akt and ERK1/2 signaling pathways].
Journal: Zhonghua xin xue guan bing za zhi 20080801
Title: Posaconazole in the management of refractory invasive fungal infections.
Journal: Therapeutics and clinical risk management 20080801
Title: The Relationship Between HIV Infection and Cardiovascular Disease.
Journal: Current cardiology reviews 20080801
Title: Cloning and characterization of monacolin K biosynthetic gene cluster from Monascus pilosus.
Journal: Journal of agricultural and food chemistry 20080723
Title: Statins activate a mitochondria-operated pathway of apoptosis in breast tumor cells by a mechanism regulated by ErbB2 and dependent on the prenylation of proteins.
Journal: FEBS letters 20080723
Title: Solubility of lovastatin in a family of six alcohols: Ethanol, 1-propanol, 1-butanol, 1-pentanol, 1-hexanol, and 1-octanol.
Journal: International journal of pharmaceutics 20080709
Title: Anticancer effects of Chinese red yeast rice versus monacolin K alone on colon cancer cells.
Journal: The Journal of nutritional biochemistry 20080701
Title: Method for comparing the structures of protein ligand-binding sites and application for predicting protein-drug interactions.
Journal: Proteins 20080701
Title: Efficacy and safety of disodium ascorbyl phytostanol phosphates in men with moderate dyslipidemia.
Journal: European journal of clinical pharmacology 20080701
Title: Induction of apoptosis in neurofibromatosis type 1 malignant peripheral nerve sheath tumor cell lines by a combination of novel farnesyl transferase inhibitors and lovastatin.
Journal: The Journal of pharmacology and experimental therapeutics 20080701
Title: Red mold rice extract represses amyloid beta peptide-induced neurotoxicity via potent synergism of anti-inflammatory and antioxidative effect.
Journal: Applied microbiology and biotechnology 20080701
Title: Novel intermolecular iterative mechanism for biosynthesis of mycoketide catalyzed by a bimodular polyketide synthase.
Journal: PLoS biology 20080701
Title: Rhabdomyolysis and pancreatitis associated with coadministration of danazol 600 mg/d and lovastatin 40 mg/d.
Journal: Clinical therapeutics 20080701
Title: Evidence for AMPK-dependent regulation of exocytosis of lipoproteins in a model liver cell line.
Journal: Experimental cell research 20080610
Title: Selective binding of sterol regulatory element-binding protein isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver.
Journal: The Journal of biological chemistry 20080606
Title: Statins reduce neuronal alpha-synuclein aggregation in in vitro models of Parkinson's disease.
Journal: Journal of neurochemistry 20080601
Title: Atorvastatin and uptake of ultrasmall superparamagnetic iron oxide nanoparticles (Ferumoxtran-10) in human monocyte-macrophages: implications for magnetic resonance imaging.
Journal: Biomaterials 20080601
Title: Impact of the FcgammaII-receptor on quartz uptake and inflammatory response by alveolar macrophages.
Journal: American journal of physiology. Lung cellular and molecular physiology 20080601
Title: The comparative effectiveness of rosuvastatin vs. other statins in patients with an increased risk of failure to reach NCEP ATP III goal.
Journal: International journal of clinical practice 20080601
Title: Efficacy of lipid-lowering medications in patients treated with clozapine: a naturalistic study.
Journal: Journal of clinical psychopharmacology 20080601
Title: Environmental induction of white-opaque switching in Candida albicans.
Journal: PLoS pathogens 20080601
Title: Evaluation of coenzyme Q as an antioxidant strategy for Alzheimer's disease.
Journal: Journal of Alzheimer's disease : JAD 20080601
Title: Current industrial practices in assessing CYP450 enzyme induction: preclinical and clinical.
Journal: The AAPS journal 20080601
Title: Atorvastatin and cardiovascular risk in the elderly--patient considerations.
Journal: Clinical interventions in aging 20080601
Title: [Pleiotropic effects of statins].
Journal: Revista medica de Chile 20080601
Title: [Advance in the study of compounds inducing the expression of heme oxygenase-1].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080601
Title: The use of fondaparinux for the treatment of venous thromboembolism in a patient with heparin-induced thombocytopenia and thrombosis caused by heparin flushes.
Journal: Therapeutics and clinical risk management 20080601
Title: Relative safety profiles of high dose statin regimens.
Journal: Vascular health and risk management 20080601
Title: Can consumers self-select for appropriate use of an over-the-counter statin? The Self Evaluation of Lovastatin to Enhance Cholesterol Treatment Study.
Journal: The American journal of cardiology 20080515
Title: Zooplankton chitobiase activity as an endpoint of pharmaceutical effect.
Journal: Archives of environmental contamination and toxicology 20080501
Title: Determination of lovastatin in human plasma by ultra-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
Journal: Biomedical chromatography : BMC 20080501
Title: Histone modifications and chromatin dynamics: a focus on filamentous fungi.
Journal: FEMS microbiology reviews 20080501
Title: Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis.
Journal: Molecular pharmacology 20080501
Title: Lovastatin inhibits amyloid precursor protein (APP) beta-cleavage through reduction of APP distribution in Lubrol WX extractable low density lipid rafts.
Journal: Journal of neurochemistry 20080501
Title: Human urotensin II induces tissue factor and cellular adhesion molecules expression in human coronary endothelial cells: an emerging role for urotensin II in cardiovascular disease.
Journal: Journal of thrombosis and haemostasis : JTH 20080501
Title: Lovastatin inhibits formation of AA amyloid.
Journal: Journal of leukocyte biology 20080501
Title: Therapeutic potential of statins in thyroid proliferative disease.
Journal: Nature clinical practice. Endocrinology & metabolism 20080501
Title: Lovastatin interferes with the infarct size-limiting effect of ischemic preconditioning and postconditioning in rat hearts.
Journal: American journal of physiology. Heart and circulatory physiology 20080501
Title: Bioconversion of lovastatin to a novel statin by Amycolatopsis sp.
Journal: Applied microbiology and biotechnology 20080501
Title: Genomewide location analysis of Candida albicans Upc2p, a regulator of sterol metabolism and azole drug resistance.
Journal: Eukaryotic cell 20080501
Title: Atorvastatin monotherapy vs. combination therapy in the management of patients with combined hyperlipidemia.
Journal: European journal of internal medicine 20080501
Title: Lovastatin biosynthetic genes of Aspergillus terreus are expressed differentially in solid-state and in liquid submerged fermentation.
Journal: Applied microbiology and biotechnology 20080501
Title: Lovastatin enhances the antitumoral and apoptotic activity of doxorubicin in murine tumor models.
Journal: Oncology reports 20080501
Title: [Determination of simvastatin in human plasma using ultra-performance liquid chromatography-tandem mass spectrometry].
Journal: Se pu = Chinese journal of chromatography 20080501
Title: The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor lovastatin reduces severity of L-DOPA-induced abnormal involuntary movements in experimental Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080423
Title: Transforming growth factor-beta1 (TGFbeta1) stimulates connective tissue growth factor (CCN2/CTGF) expression in human gingival fibroblasts through a RhoA-independent, Rac1/Cdc42-dependent mechanism: statins with forskolin block TGFbeta1-induced CCN2/CTGF expression.
Journal: The Journal of biological chemistry 20080418
Title: The safety of niacin in the US Food and Drug Administration adverse event reporting database.
Journal: The American journal of cardiology 20080417
Title: The effect of HMG-CoA reductase inhibitors on naturally occurring CD4+CD25+ T cells.
Journal: Atherosclerosis 20080401
Title: Cholesterol modulates cellular TGF-beta responsiveness by altering TGF-beta binding to TGF-beta receptors.
Journal: Journal of cellular physiology 20080401
Title: Regulation of the PTEN promoter by statins and SREBP.
Journal: Human molecular genetics 20080401
Title: Intracellular cholesterol modifies the ERAD of glucocerebrosidase in Gaucher disease patients.
Journal: Molecular genetics and metabolism 20080401
Title: Madin-Darby canine kidney II cells: a pharmacologically validated system for NPC1L1-mediated cholesterol uptake.
Journal: Molecular pharmacology 20080401
Title: Lovastatin inhibits bronchial hyperresponsiveness by reducing RhoA signaling in rat allergic asthma.
Journal: American journal of physiology. Lung cellular and molecular physiology 20080401
Title: Mechanisms of leukocyte migration across the blood-retina barrier.
Journal: Seminars in immunopathology 20080401
Title: Differential regulation of neutrophil CD18 integrin function by di- and tri-valent cations: manganese vs. gadolinium.
Journal: Annals of biomedical engineering 20080401
Title: Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells.
Journal: Liver international : official journal of the International Association for the Study of the Liver 20080401
Title: Lipid levels and low-density lipoprotein cholesterol goal attainment in diabetic patients: rosuvastatin compared with other statins in usual care.
Journal: Expert opinion on pharmacotherapy 20080401
Title: Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells.
Journal: The American journal of gastroenterology 20080401
Title: Statins in esophageal cancer cell lines: promising lead?
Journal: The American journal of gastroenterology 20080401
Title: Statins and cancer risk.
Journal: The American journal of medicine 20080401
Title: Human chorionic gonadotropin (hCG) interacts with lovastatin and ionizing radiation to modulate prostate cancer cell viability in vivo.
Journal: Cancer biology & therapy 20080401
Title: Statins increase p21 through inhibition of histone deacetylase activity and release of promoter-associated HDAC1/2.
Journal: Cancer research 20080401
Title: Biphasic effects of atorvastatin on inflammation.
Journal: Pakistan journal of pharmaceutical sciences 20080401
Title: [Use of statins in children].
Journal: Anales de pediatria (Barcelona, Spain : 2003) 20080401
Title: Determination of lovastatin hydroxy acid in female B6C3F1 mouse serum.
Journal: Journal of analytical toxicology 20080401
Title: A multipronged approach to prostate cancer.
Journal: Cancer biology & therapy 20080401
Title: Pharmacological topics of bone metabolism: antiresorptive microbial compounds that inhibit osteoclast differentiation, function, and survival.
Journal: Journal of pharmacological sciences 20080401
Title: [Effect of assorted use of Chinese drugs for detoxifying and activating blood circulation on serum high sensitive C-reactive protein in apolipoprotein E gene knock-out mice].
Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20080401
Title: Combination therapy in cholesterol reduction: focus on ezetimibe and statins.
Journal: Vascular health and risk management 20080401
Title: Clinical efficacy and safety of statins in managing cardiovascular risk.
Journal: Vascular health and risk management 20080401
Title: Preferred drug lists: potential impact on healthcare economics.
Journal: Vascular health and risk management 20080401
Title: Monascus purpureus Went rice in nephrotic hyperlipidemia.
Journal: Indian journal of nephrology 20080401
Title: Rapid liquid chromatography-tandem mass spectrometry method for the determination of a broad mixture of pharmaceuticals in surface water.
Journal: Journal of chromatography. A 20080328
Title: Differences in antitumor effects of various statins on human pancreatic cancer.
Journal: International journal of cancer 20080315
Title: Increased basolateral sorting of carcinoembryonic antigen in a polarized colon carcinoma cell line after cholesterol depletion-Implications for treatment of inflammatory bowel disease.
Journal: World journal of gastroenterology 20080314
Title: An improved and fully validated LC-MS/MS method for the simultaneous quantification of simvastatin and simvastatin acid in human plasma.
Journal: Journal of pharmaceutical and biomedical analysis 20080313
Title: Determination of lovastatin in human plasma by ultra-performance liquid chromatography-electrospray ionization tandem mass spectrometry and its application in a pharmacokinetic study.
Journal: Journal of pharmaceutical and biomedical analysis 20080313
Title: Inhibition of ABC transporters abolishes antimony resistance in Leishmania Infection.
Journal: Antimicrobial agents and chemotherapy 20080301
Title: Inhibition of geranylgeranyl diphosphate synthase induces apoptosis through multiple mechanisms and displays synergy with inhibition of other isoprenoid biosynthetic enzymes.
Journal: The Journal of pharmacology and experimental therapeutics 20080301
Title: The Food and Drug Administration and over-the-counter statins: an opportunity lost?
Journal: Journal of clinical hypertension (Greenwich, Conn.) 20080301
Title: Flexible initial dosing of atorvastatin based upon initial low-density lipoprotein cholesterol levels in type 2 diabetic patients.
Journal: The Korean journal of internal medicine 20080301
Title: Statins impair antitumor effects of rituximab by inducing conformational changes of CD20.
Journal: PLoS medicine 20080301
Title: Lovastatin induces neuroprotection through tumor necrosis factor receptor 2 signaling pathways.
Journal: Journal of Alzheimer's disease : JAD 20080301
Title: [Prescription patterns for antilipidemic drugs in a group of Colombian patients].
Journal: Revista panamericana de salud publica = Pan American journal of public health 20080301
Title: [Biosynthesis of simvastatin--a mini-review].
Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20080301
Title: Partial blockage of sterol biosynthesis with a squalene synthase inhibitor in early postnatal Niemann-Pick type C npcnih null mice brains reduces neuronal cholesterol accumulation, abrogates astrogliosis, but may inhibit myelin maturation.
Journal: Journal of neuroscience methods 20080215
Title: Reversal of chemoresistance and enhancement of apoptosis by statins through down-regulation of the NF-kappaB pathway.
Journal: Biochemical pharmacology 20080215
Title: Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis.
Journal: Journal of neuro-oncology 20080201
Title: The economic consequences of noncompliance in cardiovascular disease and related conditions: a literature review.
Journal: International journal of clinical practice 20080201
Title: Class effects of statins in elderly patients with congestive heart failure: a population-based analysis.
Journal: American heart journal 20080201
Title: New developments in medulloblastoma treatment: the potential of a cyclopamine-lovastatin combination.
Journal: Expert opinion on investigational drugs 20080201
Title: Statins induce lethal effects in acute myeloblastic leukemia [corrected] cells within 72 hours.
Journal: Leukemia & lymphoma 20080201
Title: Comparative anticancer effects of flavonoids and diazepam in cultured cancer cells.
Journal: Biological & pharmaceutical bulletin 20080201
Title: Pharmacokinetics and bioequivalence study of two tablet formulations of lovastatin in healthy volunteers.
Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20080201
Title: Red yeast rice and omega-3 fatty acids for cholesterol management.
Journal: South Dakota medicine : the journal of the South Dakota State Medical Association 20080201
Title: Update on the use of fibrates: focus on bezafibrate.
Journal: Vascular health and risk management 20080201
Title: Perioperative use of statins in noncardiac surgery.
Journal: Vascular health and risk management 20080201
Title: High density lipoprotein cholesterol: an evolving target of therapy in the management of cardiovascular disease.
Journal: Vascular health and risk management 20080201
Title: The real code of leonardo da vinci.
Journal: Current cardiology reviews 20080201
Title: Comparing pharmacokinetic and pharmacodynamic profiles in female rats orally exposed to lovastatin by gavage versus diet.
Journal: Chemico-biological interactions 20080130
Title: The association between statins and cancer incidence in a veterans population.
Journal: Journal of the National Cancer Institute 20080116
Title: Effects of lovastatin on Rho isoform expression, activity, and association with guanine nucleotide dissociation inhibitors.
Journal: Biochemical pharmacology 20080115
Title: FDA advisers again reject nonprescription lovastatin.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080115
Title: Synergistic induction of apoptosis by HMG-CoA reductase inhibitor and histone deacetylases inhibitor in HeLa cells.
Journal: Biochemical and biophysical research communications 20080111
Title: Lovastatin protects mesenchymal stem cells against hypoxia- and serum deprivation-induced apoptosis by activation of PI3K/Akt and ERK1/2.
Journal: Journal of cellular biochemistry 20080101
Title: Geranylgeranyl pyrophosphate stimulates gamma-secretase to increase the generation of Abeta and APP-CTFgamma.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080101
Title: Hydrophobic but not hydrophilic statins enhance phagocytosis and decrease apoptosis of human peripheral blood cells in vitro.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080101
Title: Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling.
Journal: Planta 20080101
Title: Screening statins for possible carcinogenic risk: up to 9 years of follow-up of 361,859 recipients.
Journal: Pharmacoepidemiology and drug safety 20080101
Title: Pancreatic stellate cells: new target in the treatment of chronic pancreatitis.
Journal: Journal of gastroenterology and hepatology 20080101
Title: Statin use and risk of breast cancer.
Journal: Cancer 20080101
Title: In vitro mechanisms of lovastatin on lung cancer cell lines as a potential chemopreventive agent.
Journal: Lung 20080101
Title: Lovastatin inhibits oxidized low-density lipoprotein-induced plasminogen activator inhibitor and transforming growth factor-beta1 expression via a decrease in Ras/extracellular signal-regulated kinase activity in mesangial cells.
Journal: Translational research : the journal of laboratory and clinical medicine 20080101
Title: Statin modulates insulin signaling and insulin resistance in liver and muscle of rats fed a high-fat diet.
Journal: Metabolism: clinical and experimental 20080101
Title: Ciglitazone, an agonist of peroxisome proliferator-activated receptor gamma, exerts potentiated cytostatic/cytotoxic effects against tumor cells when combined with lovastatin.
Journal: International journal of oncology 20080101
Title: Effects of lovastatin alone or combined with irradiation on tumor cells in vitro and in vivo.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20080101
Title: The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells.
Journal: BMC cancer 20080101
Title: Statin induces apoptosis and cell growth arrest in prostate cancer cells.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080101
Title: Incidence of adverse events with HMG-CoA reductase inhibitors in liver transplant patients.
Journal: Clinical transplantation 20080101
Title: Evidence for horizontal transfer of a secondary metabolite gene cluster between fungi.
Journal: Genome biology 20080101
Title: Cell cycle and cell death are not necessary for appressorium formation and plant infection in the fungal plant pathogen Colletotrichum gloeosporioides.
Journal: BMC biology 20080101
Title: Peroxisome proliferator activated receptors and lipoprotein metabolism.
Journal: PPAR research 20080101
Title: Opossum carboxylesterases: sequences, phylogeny and evidence for CES gene duplication events predating the marsupial-eutherian common ancestor.
Journal: BMC evolutionary biology 20080101
Title: Frequency and clinical relevance of drug interactions with lovastatin and simvastatin: an observational database study.
Journal: Drug safety 20080101
Title: Does productivity influence priority setting? A case study from the field of CVD prevention.
Journal: Cost effectiveness and resource allocation : C/E 20080101
Title: [New approaches to the drug prophylaxis of mammary tumor: evaluation of the prophylactic effect of lovastatin and captopril in rats with experimental mammary gland tumors].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20080101
Title: Hepatic effects of lovastatin exposure in patients with liver disease: a retrospective cohort study.
Journal: Drug safety 20080101
Title: The Lipid lowering and Onset of Renal Disease (LORD) Trial: a randomized double blind placebo controlled trial assessing the effect of atorvastatin on the progression of kidney disease.
Journal: BMC nephrology 20080101
Title: Fosamprenavir or atazanavir once daily boosted with ritonavir 100 mg, plus tenofovir/emtricitabine, for the initial treatment of HIV infection: 48-week results of ALERT.
Journal: AIDS research and therapy 20080101
Title: Chinese red yeast rice (Monascus purpureus-fermented rice) promotes bone formation.
Journal: Chinese medicine 20080101
Title: Analysis of Aspergillus nidulans metabolism at the genome-scale.
Journal: BMC genomics 20080101
Title: Changes in cholesterol kinetics following sugar cane policosanol supplementation: a randomized control trial.
Journal: Lipids in health and disease 20080101
Title: Farnesyl transferase inhibitors induce extended remissions in transgenic mice with mature B cell lymphomas.
Journal: Molecular cancer 20080101
Title: Interaction of the HMG-CoA reductase inhibitor lovastatin and nitric oxide in cardiomyocyte cell death.
Journal: Pharmacology 20080101
Title: A Role for the PPARgamma in Cancer Therapy.
Journal: PPAR research 20080101
Title: Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin.
Journal: Clinical pharmacokinetics 20080101
Title: Potentiation of nerve growth factor-induced neurite outgrowth by fluvoxamine: role of sigma-1 receptors, IP3 receptors and cellular signaling pathways.
Journal: PloS one 20080101
Title: Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key?
Journal: PPAR research 20080101
Title: Secondary prevention of coronary heart disease in elderly patients following myocardial infarction: are all HMG-CoA reductase inhibitors alike?
Journal: Drugs & aging 20080101
Title: Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin.
Journal: BMC medicine 20080101
Title: Statins, bone, and neurofibromatosis type 1.
Journal: BMC medicine 20080101
Title: Yeast cell factories for fine chemical and API production.
Journal: Microbial cell factories 20080101
Title: 15-deoxy-delta12,14-prostaglandin J2 attenuates endothelial-monocyte interaction: implication for inflammatory diseases.
Journal: Journal of inflammation (London, England) 20080101
Title: Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats.
Journal: BMC pharmacology 20080101
Title: Activated PPARgamma Targets Surface and Intracellular Signals That Inhibit the Proliferation of Lung Carcinoma Cells.
Journal: PPAR research 20080101
Title: Use of rosiglitazone before and after vascular injury in hypercholesterolemic rabbits: Assessment of neointimal formation.
Journal: Thrombosis journal 20080101
Title: Effects of krill oil on serum lipids of hyperlipidemic rats and human SW480 cells.
Journal: Lipids in health and disease 20080101
Title: Influence of sodium monoketocholate on the hypolipidemic activity of lovastatin in healthy and diabetic rats.
Journal: European journal of drug metabolism and pharmacokinetics 20080101
Title: PPARgamma: The Portrait of a Target Ally to Cancer Chemopreventive Agents.
Journal: PPAR research 20080101
Title: Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells.
Journal: BMC biology 20080101
Title: Non-healing painful ulcers in a patient with chronic kidney disease and role of sodium thiosulfate: a case report.
Journal: Cases journal 20080101
Title: Unlocking the power of cross-species genomic analyses: identification of evolutionarily conserved breast cancer networks and validation of preclinical models.
Journal: Breast cancer research : BCR 20080101
Title: Inhibition of antigen-induced bronchial smooth muscle hyperresponsiveness by lovastatin in mice.
Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20080101
Title: The prince and the pauper. A tale of anticancer targeted agents.
Journal: Molecular cancer 20080101
Title: In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites.
Journal: BMC bioinformatics 20080101
Title: Net efficacy adjusted for risk (NEAR): a simple procedure for measuring risk:benefit balance.
Journal: PloS one 20080101
Title: Implementing shared decision-making in nutrition clinical practice: a theory-based approach and feasibility study.
Journal: Implementation science : IS 20080101
Title: The effects of lovastatin on conventional medical treatment of lower urinary tract symptoms with finasteride.
Journal: International braz j urol : official journal of the Brazilian Society of Urology 20080101
Title: Dynamical modeling of the cholesterol regulatory pathway with Boolean networks.
Journal: BMC systems biology 20080101
Title: Defective rotavirus particle assembly in lovastatin-treated MA104 cells.
Journal: Archives of virology 20080101
Title: Design of floating bilayer tablets of diltiazem hydrochloride and lovastatin.
Journal: PDA journal of pharmaceutical science and technology 20080101
Title: Improved Insulin Resistance and Lipid Metabolism by Cinnamon Extract through Activation of Peroxisome Proliferator-Activated Receptors.
Journal: PPAR research 20080101
Title: PPARgamma, PTEN, and the Fight against Cancer.
Journal: PPAR research 20080101
Title: Clinical Use of PPARgamma Ligands in Cancer.
Journal: PPAR research 20080101
Title: Oxidative imbalance in nonstimulated X-adrenoleukodystrophy-derived lymphoblasts.
Journal: Developmental neuroscience 20080101
Title: HMG-CoA reductase is regulated by environmental salinity and its activity is essential for halotolerance in halophilic fungi.
Journal: Studies in mycology 20080101
Title: Statin treatment, carotid atherosclerotic plaque macrophage infiltration and circulating inflammatory markers.
Journal: The open cardiovascular medicine journal 20080101
Title: Sphincter of Oddi and its dysfunction.
Journal: Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20080101
Title: Determination of key intermediates in cholesterol and bile acid biosynthesis by stable isotope dilution mass spectrometry.
Journal: Analytical chemistry insights 20080101
Title: Microbial production and biomedical applications of lovastatin.
Journal: Indian journal of pharmaceutical sciences 20080101
Title: Frequency and predictors of tablet splitting in statin prescriptions: a population-based analysis.
Journal: Open medicine : a peer-reviewed, independent, open-access journal 20080101
Title: A simple and rapid approach for removing citrinin while retaining monacolin K in red mold rice.
Journal: Journal of agricultural and food chemistry 20071226
Title: The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity.
Journal: The Journal of clinical investigation 20071203
Title: Comparison of a dietary portfolio diet of cholesterol-lowering foods and a statin on LDL particle size phenotype in hypercholesterolaemic participants.
Journal: The British journal of nutrition 20071201
Title: Simultaneous biosynthesis of (+)-geodin by a lovastatin-producing fungus Aspergillus terreus.
Journal: Journal of biotechnology 20071201
Title: Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells.
Journal: Lipids 20071201
Title: Evidence of artemisinin production from IPP stemming from both the mevalonate and the nonmevalonate pathways.
Journal: Plant cell reports 20071201
Title: P-glycoprotein is downregulated in KG1a-primitive leukemia cells by LDL cholesterol deprivation and by HMG-CoA reductase inhibitors.
Journal: Experimental hematology 20071201
Title: Hypolipidemic and antioxidant effects of ethanolic extract from dried calyx of Hibiscus sabdariffa in alloxan-induced diabetic rats.
Journal: Fundamental & clinical pharmacology 20071201
Title: The antitumour activities of statins.
Journal: Current oncology (Toronto, Ont.) 20071201
Title: Zoledronic acid affects over-angiogenic phenotype of endothelial cells in patients with multiple myeloma.
Journal: Molecular cancer therapeutics 20071201
Title: Understanding practice patterns and low-density lipoprotein cholesterol goal attainment implications of switching patients from simvastatin in a health plan setting.
Journal: The American journal of managed care 20071201
Title: 3-hydroxy-3-methylglutaryl coenzyme a reductase 1 interacts with NORK and is crucial for nodulation in Medicago truncatula.
Journal: The Plant cell 20071201
Title: Aliskiren--an orally active renin inhibitor. Review of pharmacology, pharmacodynamics, kinetics, and clinical potential in the treatment of hypertension.
Journal: Vascular health and risk management 20071201
Title: The antioxidant effect of lovastatin on phagocyte-induced DNA damage: implications for cancer prevention.
Journal: Journal of experimental & clinical cancer research : CR 20071201
Title: [Protection of vascular endothelial cells from ox-LDL induced injury by protocatechualdehyde].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071201
Title: Anti-inflammatory and immune therapy for Alzheimer's disease: current status and future directions.
Journal: Current neuropharmacology 20071201
Title: Structural elucidation of an unknown Simvastatin by-product in industrial synthesis starting from Lovastatin.
Journal: Journal of pharmaceutical and biomedical analysis 20071130
Title: The impact of generic reference pricing interventions in the statin market.
Journal: Health policy (Amsterdam, Netherlands) 20071101
Title: Red mold rice ameliorates impairment of memory and learning ability in intracerebroventricular amyloid beta-infused rat by repressing amyloid beta accumulation.
Journal: Journal of neuroscience research 20071101
Title: Lovastatin enhances the replication of the oncolytic adenovirus dl1520 and its antineoplastic activity against anaplastic thyroid carcinoma cells.
Journal: Endocrinology 20071101
Title: Lovastatin induces the expression of bradykinin type 2 receptors in cultured human coronary artery endothelial cells.
Journal: Journal of molecular and cellular cardiology 20071101
Title: Effect of combining viscous fibre with lovastatin on serum lipids in normal human subjects.
Journal: International journal of clinical practice 20071101
Title: Effects of vitamin E on cholesterol levels of hypercholesterolemic patients receiving statins.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20071101
Title: Cholesterol-lowering drugs and prostate cancer risk: a population-based case-control study.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20071101
Title: Synergistic activity of the histone deacetylase inhibitor suberoylanilide hydroxamic acid and the bisphosphonate zoledronic acid against prostate cancer cells in vitro.
Journal: Molecular cancer therapeutics 20071101
Title: Comparative evaluation of the effects of statins on human stem and cancer cells in vitro.
Journal: Reproductive biomedicine online 20071101
Title: Antifungal activity of statins against Aspergillus species.
Journal: Medical mycology 20071101
Title: Titration patterns with rosuvastatin as compared with other statins in clinical practice: a retrospective observational cohort study using an electronic medical record database.
Journal: Clinical therapeutics 20071101
Title: Comparison of a statin vs. hypolipemic diet on the oxidant status in hemodialyzed patients with chronic renal failure.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20071101
Title: Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis.
Journal: Journal of cell science 20071015
Title: Activation of the integrated stress response regulates lovastatin-induced apoptosis.
Journal: The Journal of biological chemistry 20071012
Title: Locally delivered lovastatin nanoparticles enhance fracture healing in rats.
Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20071001
Title: Risk of congenital anomalies in pregnant users of statin drugs.
Journal: British journal of clinical pharmacology 20071001
Title: Salicylic acid-induced taxol production and isopentenyl pyrophosphate biosynthesis in suspension cultures of Taxus chinensis var. mairei.
Journal: Cell biology international 20071001
Title: Growth hormone (GH) replacement decreases serum total and LDL-cholesterol in hypopituitary patients on maintenance HMG CoA reductase inhibitor (statin) therapy.
Journal: Clinical endocrinology 20071001
Title: P-glycoprotein has differential effects on the disposition of statin acid and lactone forms in mdr1a/b knockout and wild-type mice.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20071001
Title: ICAM-1 peptide inhibitors of T-cell adhesion bind to the allosteric site of LFA-1. An NMR characterization.
Journal: Chemical biology & drug design 20071001
Title: Effectiveness of statins in Medicare-eligible patients and patients < 65 years using clinical practice data.
Journal: International journal of clinical practice 20071001
Title: The road to LOAD: late-onset Alzheimer's disease and a possible way to block it.
Journal: Expert opinion on therapeutic targets 20071001
Title: The effect of statins in colorectal cancer is mediated through the bone morphogenetic protein pathway.
Journal: Gastroenterology 20071001
Title: Life style-related diseases of the digestive system: cell culture system for the screening of anti-hepatitis C virus (HCV) reagents: suppression of HCV replication by statins and synergistic action with interferon.
Journal: Journal of pharmacological sciences 20071001
Title: A meta-analysis to evaluate the efficacy of statins in children with familial hypercholesterolemia.
Journal: International journal of clinical pharmacology and therapeutics 20071001
Title: Comparison of the efficacies of five different statins on inhibition of human saphenous vein smooth muscle cell proliferation and invasion.
Journal: Journal of cardiovascular pharmacology 20071001
Title: The role of HMG-CoA reductase inhibition in endothelial dysfunction and inflammation.
Journal: Vascular health and risk management 20071001
Title: Cholesterol lowering for secondary prevention: what statin dose should we use?
Journal: Vascular health and risk management 20071001
Title: Colesevelam hydrochloride: reducing atherosclerotic coronary heart disease risk factors.
Journal: Vascular health and risk management 20071001
Title: Mitochondrial impairment by PPAR agonists and statins identified via immunocaptured OXPHOS complex activities and respiration.
Journal: Toxicology and applied pharmacology 20070915
Title: Statins reduce amyloid-beta production through inhibition of protein isoprenylation.
Journal: The Journal of biological chemistry 20070914
Title: Inhibition of the mevalonate pathway and activation of p38 MAP kinase are independently regulated by nitrogen-containing bisphosphonates in breast cancer cells.
Journal: European journal of pharmacology 20070910
Title: Increased smooth muscle cell expression of caveolin-1 and caveolae contribute to the pathophysiology of idiopathic pulmonary arterial hypertension.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070901
Title: A phase I study to assess the safety and activity of topical lovastatin (FP252S) for the prevention of chemotherapy-induced alopecia.
Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20070901
Title: Statins prevent cholinesterase inhibitor blockade of sympathetic alpha7-nAChR-mediated currents in rat superior cervical ganglion neurons.
Journal: American journal of physiology. Heart and circulatory physiology 20070901
Title: The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet.
Journal: Biopharmaceutics & drug disposition 20070901
Title: Effect of statin and angiotensin-converting enzyme inhibition on structural and hemodynamic alterations in autosomal dominant polycystic kidney disease model.
Journal: American journal of physiology. Renal physiology 20070901
Title: Effectiveness of rosuvastatin in low-density lipoprotein cholesterol lowering and National Cholesterol Education Program Adult Treatment Panel guideline III LDL-C goal attainment compared to other statins among diabetes mellitus patients: a retrospective study using an electronic medical records dataset in the United States.
Journal: Current medical research and opinion 20070901
Title: Lovastatin enhances phenylbutyrate-induced MR-visible glycerophosphocholine but not apoptosis in DU145 prostate cells.
Journal: Biochimica et biophysica acta 20070901
Title: A new perspective on nonprescription statins: an opportunity for patient education and involvement.
Journal: The American journal of cardiology 20070901
Title: Optimization of production of monacolin K from gamma-irradiated Monascus mutant by use of response surface methodology.
Journal: Journal of medicinal food 20070901
Title: Low-density lipoprotein cholesterol (LDL-C) levels and LDL-C goal attainment among elderly patients treated with rosuvastatin compared with other statins in routine clinical practice.
Journal: The American journal of geriatric pharmacotherapy 20070901
Title: Ask the doctor. I saw a newspaper column that said red yeast rice is a safer, more effective way to treat high cholesterol than statin drugs. Is that true?
Journal: Harvard heart letter : from Harvard Medical School 20070901
Title: The molecular genetics of breast cancer and targeted therapy.
Journal: Biologics : targets & therapy 20070901
Title: Strategies for eliminating PrP(c) as substrate for prion conversion and for enhancing PrP(Sc) degradation.
Journal: Veterinary microbiology 20070831
Title: Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease.
Journal: Neurology 20070828
Title: Red mold dioscorea has greater hypolipidemic and antiatherosclerotic effect than traditional red mold rice and unfermented dioscorea in hamsters.
Journal: Journal of agricultural and food chemistry 20070822
Title: Lovastatin suppresses erythropoietin receptor surface expression through dual inhibition of glycosylation and geranylgeranylation.
Journal: Biochemical pharmacology 20070815
Title: Improving the ratio of monacolin K to citrinin production of Monascus purpureus NTU 568 under dioscorea medium through the mediation of pH value and ethanol addition.
Journal: Journal of agricultural and food chemistry 20070808
Title: Chemotherapy and zoledronate sensitize solid tumour cells to Vgamma9Vdelta2 T cell cytotoxicity.
Journal: Cancer immunology, immunotherapy : CII 20070801
Title: Statins in elderly patients with acute coronary syndrome: an analysis of dose and class effects in typical practice.
Journal: Heart (British Cardiac Society) 20070801
Title: Effect of reduced levels of the LDL receptor of Ehrlich ascites tumor cells on cholesterol uptake and cell proliferation: a coculture study with baby hamster kidney cells.
Journal: Cell biology international 20070801
Title: Atorvastatin glucuronidation is minimally and nonselectively inhibited by the fibrates gemfibrozil, fenofibrate, and fenofibric acid.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070801
Title: Simvastatin inhibits IFN-gamma-induced CD40 gene expression by suppressing STAT-1alpha.
Journal: Journal of leukocyte biology 20070801
Title: Establishing the benefit of statins in low-to-moderate--risk primary prevention: the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS).
Journal: Atherosclerosis. Supplements 20070801
Title: On the factors modulating the effect of statins on malignant cell proliferation.
Journal: Cancer investigation 20070801
Title: Impact of statin dosing intensity on transaminase and creatine kinase.
Journal: The American journal of medicine 20070801
Title: Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus.
Journal: PLoS pathogens 20070801
Title: Prolonged-release nicotinic acid for the management of dyslipidemia: an update including results from the NAUTILUS study.
Journal: Vascular health and risk management 20070801
Title: Review of tipranavir in the treatment of drug-resistant HIV.
Journal: Therapeutics and clinical risk management 20070801
Title: Evaluation of patient care interventions and recommendations by a transitional care pharmacist.
Journal: Therapeutics and clinical risk management 20070801
Title: Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials.
Journal: Journal of the American College of Cardiology 20070731
Title: Lack of evidence of a clopidogrel-statin interaction in the CHARISMA trial.
Journal: Journal of the American College of Cardiology 20070724
Title: A macrokinetic modelling of the biosynthesis of lovastatin by Aspergillus terreus.
Journal: Journal of biotechnology 20070715
Title: Synthesis, biochemical, and cellular evaluation of farnesyl monophosphate prodrugs as farnesyltransferase inhibitors.
Journal: Journal of medicinal chemistry 20070712
Title: Survivin down-regulation plays a crucial role in 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor-induced apoptosis in cancer.
Journal: The Journal of biological chemistry 20070706
Title: Lovastatin improves histological and functional outcomes and reduces inflammation after experimental traumatic brain injury.
Journal: Life sciences 20070704
Title: Esterase inhibition attribute of grapefruit juice leading to a new drug interaction.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070701
Title: Apomine enhances the antitumor effects of lovastatin on myeloma cells by down-regulating 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Journal: The Journal of pharmacology and experimental therapeutics 20070701
Title: Esterase inhibition by grapefruit juice flavonoids leading to a new drug interaction.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070701
Title: SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma.
Journal: Journal of lipid research 20070701
Title: Rac1, RhoA, and Cdc42 participate in HeLa cell invasion by group B streptococcus.
Journal: FEMS microbiology letters 20070701
Title: Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells.
Journal: European journal of cell biology 20070701
Title: Improving simvastatin bioconversion in Escherichia coli by deletion of bioH.
Journal: Metabolic engineering 20070701
Title: Effects of lactose and glucose on production of itaconic acid and lovastatin by Aspergillus terreus ATCC 20542.
Journal: Journal of bioscience and bioengineering 20070701
Title: What do medical records tell us about potentially harmful co-prescribing?
Journal: Joint Commission journal on quality and patient safety 20070701
Title: Chromatography-mass spectrometry methods for the quantitation of statins in biological samples.
Journal: Journal of pharmaceutical and biomedical analysis 20070628
Title: Hepatitis and rhabdomyolysis in a patient with hormone refractory prostate cancer on ketoconazole and concurrent lovastatin therapy.
Journal: Investigational new drugs 20070601
Title: Modulation of COX-2 expression by statins in human monocytic cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070601
Title: Asbestos induces nitric oxide synthesis in mesothelioma cells via Rho signaling inhibition.
Journal: American journal of respiratory cell and molecular biology 20070601
Title: Effects of statins on bone mineral density: a meta-analysis of clinical studies.
Journal: Bone 20070601
Title: Biochemical characterization of the minimal polyketide synthase domains in the lovastatin nonaketide synthase LovB.
Journal: The FEBS journal 20070601
Title: Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo.
Journal: International journal of oncology 20070601
Title: German evidence-based guidelines for the treatment of Psoriasis vulgaris (short version).
Journal: Archives of dermatological research 20070601
Title: Lovastatin effects on bone mineral density in postmenopausal women with type 2 diabetes mellitus.
Journal: Acta diabetologica 20070601
Title: Determinants of sensitivity to lovastatin-induced apoptosis in multiple myeloma.
Journal: Molecular cancer therapeutics 20070601
Title: Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans.
Journal: PLoS pathogens 20070601
Title: [Experimental study of anti-atherosclerosis potency by lycium seed oil and its possible mechanism].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070601
Title: Studies on free radicals, antioxidants, and co-factors.
Journal: Clinical interventions in aging 20070601
Title: Statins synergistically potentiate 7-hydroxystaurosporine (UCN-01) lethality in human leukemia and myeloma cells by disrupting Ras farnesylation and activation.
Journal: Blood 20070515
Title: Interactions between statins and Penicillium chrysogenum antifungal protein (PAF) to inhibit the germination of sporangiospores of different sensitive Zygomycetes.
Journal: FEMS microbiology letters 20070501
Title: Effects of statins on alpha7 nicotinic receptor, cholinesterase and alpha-form of secreted amyloid precursor peptide in SH-SY5Y cells.
Journal: Neurochemistry international 20070501
Title: Lovastatin specifically prevents focal ischemic ventricular tachycardia due to triggered activity.
Journal: Heart rhythm 20070501
Title: Effect of HMGCoA reductase inhibitors on cytochrome P450 expression in endothelial cell line.
Journal: Journal of cardiovascular pharmacology 20070501
Title: In vitro study of lovastatin interactions with amiodarone and with carbon tetrachloride in isolated rat hepatocytes.
Journal: World journal of gastroenterology 20070421
Title: Beneficial effect of statins in multiple sclerosis: is it dose-dependent?
Journal: Atherosclerosis 20070401
Title: Partial silencing of a hydroxy-methylglutaryl-CoA reductase-encoding gene in Trichoderma harzianum CECT 2413 results in a lower level of resistance to lovastatin and lower antifungal activity.
Journal: Fungal genetics and biology : FG & B 20070401
Title: Synthesis and biological evaluation of unprecedented classes of spiro-beta-lactams and azido-beta-lactams as acyl-CoA:cholesterol acyltransferase inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20070401
Title: Stacking and quantitative analysis of lovastatin in urine samples by the transient moving chemical reaction boundary method in capillary electrophoresis.
Journal: Analytical and bioanalytical chemistry 20070401
Title: The effect of aggressive versus conventional lipid-lowering therapy on markers of inflammatory and oxidative stress.
Journal: Cardiovascular drugs and therapy 20070401
Title: Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans.
Journal: Nature chemical biology 20070401
Title: Tocotrienols potentiate lovastatin-mediated growth suppression in vitro and in vivo.
Journal: Experimental biology and medicine (Maywood, N.J.) 20070401
Title: [Lovastatin induction of the redundant gene: implications for therapy of X-linked adrenoleukodystrophy].
Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20070401
Title: The potential antioxidant capacity and angiotensin I-converting enzyme inhibitory activity of Monascus-fermented soybean extracts: evaluation of Monascus-fermented soybean extracts as multifunctional food additives.
Journal: Journal of food science 20070401
Title: Effect of beta-hydroxy-beta-methylglutaryl coenzyme A reductase inhibitors and antioxidant vitamins on free radical lipid oxidation in rat liver.
Journal: Bulletin of experimental biology and medicine 20070401
Title: Characterization of Salmonella enterica serovar Typhimurium DT104 invasion in an epithelial cell line (IPEC J2) from porcine small intestine.
Journal: Veterinary microbiology 20070310
Title: [The neurobiology of learning difficulties: neurofibromatosis type 1 as a model for researching and treating learning disorders].
Journal: Revista de neurologia 20070302
Title: Role of microglia in the pathogenesis of osmotic-induced demyelination.
Journal: Experimental neurology 20070301
Title: Cholesterol-dependent balance between evoked and spontaneous synaptic vesicle recycling.
Journal: The Journal of physiology 20070301
Title: Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070301
Title: Treatment of experimental autoimmune uveoretinitis with atorvastatin and lovastatin.
Journal: Experimental eye research 20070301
Title: Predicting the oxidative metabolism of statins: an application of the MetaSite algorithm.
Journal: Pharmaceutical research 20070301
Title: High-dose methylprednisolone influences the physiology and virulence of Candida albicans ambiguously and enhances the candidacidal activity of the polyene antibiotic amphotericin B and the superoxide-generating agent menadione.
Journal: FEMS yeast research 20070301
Title: Lovastatin attenuates nerve injury in an animal model of Guillain-Barré syndrome.
Journal: Journal of neurochemistry 20070301
Title: Functional analysis of the hepatic HMG-CoA reductase promoter by in vivo electroporation.
Journal: Experimental biology and medicine (Maywood, N.J.) 20070301
Title: Preparation, characterization, and in vitro and in vivo evaluation of lovastatin solid lipid nanoparticles.
Journal: AAPS PharmSciTech 20070301
Title: Neuropsychiatric consequences of cardiovascular medications.
Journal: Dialogues in clinical neuroscience 20070301
Title: C/T conversion alters interleukin-1A promoter function in a human astrocyte cell line.
Journal: Life sciences 20070227
Title: Regulation of human cytochrome P450 4F2 expression by sterol regulatory element-binding protein and lovastatin.
Journal: The Journal of biological chemistry 20070223
Title: Digeranyl bisphosphonate inhibits geranylgeranyl pyrophosphate synthase.
Journal: Biochemical and biophysical research communications 20070223
Title: Statin-induced Ras activation integrates the phosphatidylinositol 3-kinase signal to Akt and MAPK for bone morphogenetic protein-2 expression in osteoblast differentiation.
Journal: The Journal of biological chemistry 20070216
Title: Targeting EGF-receptor-signalling in squamous cell carcinomas of the head and neck.
Journal: British journal of cancer 20070212
Title: Effects of statin treatment and withdrawal on angiotensin II-induced phosphorylation of p38 MAPK and ERK1/2 in cultured vascular smooth muscle cells.
Journal: Biochemical and biophysical research communications 20070202
Title: Lovastatin protects human neurons against Abeta-induced toxicity and causes activation of beta-catenin-TCF/LEF signaling.
Journal: Neuroscience letters 20070202
Title: Haplotypes in the lipoprotein lipase gene influence high-density lipoprotein cholesterol response to statin therapy and progression of atherosclerosis in coronary artery bypass grafts.
Journal: The pharmacogenomics journal 20070201
Title: Effect of a statin on an in vitro model of endometriosis.
Journal: Fertility and sterility 20070201
Title: Decrease of cholesterol in mouse melanoma causes secretion of lysosomal enzymes.
Journal: Journal of biochemistry 20070201
Title: Lovastatin insensitive 1, a Novel pentatricopeptide repeat protein, is a potential regulatory factor of isoprenoid biosynthesis in Arabidopsis.
Journal: Plant & cell physiology 20070201
Title: Statins (HMG-CoA reductase inhibitors) decrease postoperative adhesions by increasing peritoneal fibrinolytic activity.
Journal: Annals of surgery 20070201
Title: The use of statins in postoperative adhesion prevention.
Journal: Annals of surgery 20070201
Title: c-Jun N-terminal protein kinase signalling pathway mediates lovastatin-induced rat brain neuroblast apoptosis.
Journal: Biochimica et biophysica acta 20070201
Title: Safety of lovastatin/extended release niacin compared with lovastatin alone, atorvastatin alone, pravastatin alone, and simvastatin alone (from the United States Food and Drug Administration adverse event reporting system).
Journal: The American journal of cardiology 20070201
Title: Exenatide effects on statin pharmacokinetics and lipid response.
Journal: International journal of clinical pharmacology and therapeutics 20070201
Title: Estimating the impact of adding C-reactive protein as a criterion for lipid lowering treatment in the United States.
Journal: Journal of general internal medicine 20070201
Title: Meta-analysis of drug-induced adverse events associated with intensive-dose statin therapy.
Journal: Clinical therapeutics 20070201
Title: Effect of lipid-lowering and anti-hypertensive drugs on plasma homocysteine levels.
Journal: Vascular health and risk management 20070201
Title: Lovastatin and cyclopamine combination in medulloblastoma.
Journal: Cancer biology & therapy 20070201
Title: Production of dihydroisocoumarins in Fusarium verticillioides by swapping ketosynthase domain of the fungal iterative polyketide synthase Fum1p with that of lovastatin diketide synthase.
Journal: Journal of the American Chemical Society 20070110
Title: Critical role for FoxO3a-dependent regulation of p21CIP1/WAF1 in response to statin signaling in cardiac myocytes.
Journal: Circulation research 20070105
Title: Quantitative analysis of lovastatin in capsule of Chinese medicine monascus by capillary zone electrophoresis with UV-vis detector.
Journal: Journal of pharmaceutical and biomedical analysis 20070104
Title: Syntheses of conjugated pyrones for the enzymatic assay of lovastatin nonaketide synthase, an iterative polyketide synthase.
Journal: Organic letters 20070104
Title: Herpes zoster-associated acute urinary retention: a case report.
Journal: International urogynecology journal and pelvic floor dysfunction 20070101
Title: Supplementation of the cultivation media with B-group vitamins enhances lovastatin biosynthesis by Aspergillus terreus.
Journal: Journal of biotechnology 20070101
Title: Phenantroline, lovastatin, and mebendazole do not inhibit oviposition in the murine experimental infection with Angiostrongylus costaricensis.
Journal: Parasitology research 20070101
Title: Lovastatin inhibits the extracellular-signal-regulated kinase pathway in immortalized rat brain neuroblasts.
Journal: The Biochemical journal 20070101
Title: In silico prediction of pregnane X receptor activators by machine learning approaches.
Journal: Molecular pharmacology 20070101
Title: Optimization of nutrient parameters for lovastatin production by Monascus purpureus MTCC 369 under submerged fermentation using response surface methodology.
Journal: Applied microbiology and biotechnology 20070101
Title: Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers.
Journal: The Journal of pharmacology and experimental therapeutics 20070101
Title: Human chorionic gonadotropin modulates prostate cancer cell survival after irradiation or HMG CoA reductase inhibitor treatment.
Journal: Molecular pharmacology 20070101
Title: Influences of lovastatin on membrane ion flow and intracellular signaling in breast cancer cells.
Journal: Cellular & molecular biology letters 20070101
Title: Therapeutic approach to FSGS in children.
Journal: Pediatric nephrology (Berlin, Germany) 20070101
Title: Apolipoprotein E genotype affects the response to lipid-lowering therapy in Chinese patients with type 2 diabetes mellitus.
Journal: Diabetes, obesity & metabolism 20070101
Title: Hedgehog signaling promotes medulloblastoma survival via Bc/II.
Journal: The American journal of pathology 20070101
Title: Optimal low-density lipoprotein cholesterol lowering--morning versus evening statin administration.
Journal: The Annals of pharmacotherapy 20070101
Title: Probable statin-induced testicular pain.
Journal: The Annals of pharmacotherapy 20070101
Title: [Regulatory effect of Chinese herbal compound for detoxifying and activating blood circulation on expression of NF-kappaB and MMP-9 in aorta of apolipoprotein E gene knocked-out mice].
Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20070101
Title: Cost-effectiveness of medical interventions to prevent cardiovascular disease in a sub-Saharan African country--the case of Tanzania.
Journal: Cost effectiveness and resource allocation : C/E 20070101
Title: Chemical combination effects predict connectivity in biological systems.
Journal: Molecular systems biology 20070101
Title: The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases.
Journal: Immunity & ageing : I & A 20070101
Title: How equitable are GP practice prescribing rates for statins?: an ecological study in four primary care trusts in North West England.
Journal: International journal for equity in health 20070101
Title: The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention.
Journal: Molecular cancer 20070101
Title: The lipid lowering effect of plant sterol ester capsules in hypercholesterolemic subjects.
Journal: Lipids in health and disease 20070101
Title: Risk and predictability of drug interactions in the elderly.
Journal: International review of neurobiology 20070101
Title: Physicochemical characterization and dissolution study of solid dispersions of Lovastatin with polyethylene glycol 4000 and polyvinylpyrrolidone K30.
Journal: Pharmaceutical development and technology 20070101
Title: Statins disrupt CCR5 and RANTES expression levels in CD4(+) T lymphocytes in vitro and preferentially decrease infection of R5 versus X4 HIV-1.
Journal: PloS one 20070101
Title: Severe rhabdomyolysis and acute renal failure secondary to concomitant use of simvastatin, amiodarone, and atazanavir.
Journal: Journal of the American Board of Family Medicine : JABFM 20070101
Title: Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease.
Journal: BMC medicine 20070101
Title: Mevastatin increases eNO synthase expression and inhibits lipid peroxidation in human endothelial cells.
Journal: Clinical hemorheology and microcirculation 20070101
Title: Reduction of protein synthesis and statin-induced cardiomyocyte cell death.
Journal: Cardiovascular toxicology 20070101
Title: General framework for the quantitative prediction of CYP3A4-mediated oral drug interactions based on the AUC increase by coadministration of standard drugs.
Journal: Clinical pharmacokinetics 20070101
Title: HMG-CoA reductase inhibitors reduce nicotine-induced expression of cellular adhesion molecules in cultured human coronary endothelial cells.
Journal: Journal of vascular research 20070101
Title: Should we encourage over-the-counter statins? A population perspective for coronary heart disease prevention.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101
Title: Regression or reduction in progression of atherosclerosis, and avoidance of coronary events, with lovastatin in patients with or at high risk of cardiovascular disease: a review.
Journal: Clinical drug investigation 20070101
Title: An integrative in silico approach for discovering candidates for drug-targetable protein-protein interactions in interactome data.
Journal: BMC pharmacology 20070101
Title: The Role of PPARs in Lung Fibrosis.
Journal: PPAR research 20070101
Title: Determination of pitavastatin in human plasma via HPLC-ESI-MS/MS and subsequent application to a clinical study in healthy Chinese volunteers.
Journal: Clinica chimica acta; international journal of clinical chemistry 20070101
Title: The LeFE algorithm: embracing the complexity of gene expression in the interpretation of microarray data.
Journal: Genome biology 20070101
Title: Locally applied Simvastatin improves fracture healing in mice.
Journal: BMC musculoskeletal disorders 20070101
Title: Monascus rice products.
Journal: Advances in food and nutrition research 20070101
Title: Dissecting complex transcriptional responses using pathway-level scores based on prior information.
Journal: BMC bioinformatics 20070101
Title: Increased expression of CD14 in macrophages after inhibition of the cholesterol biosynthetic pathway by lovastatin.
Journal: Molecular medicine (Cambridge, Mass.) 20070101
Title: Fish-oil esters of plant sterols differ from vegetable-oil sterol esters in triglycerides lowering, carotenoid bioavailability and impact on plasminogen activator inhibitor-1 (PAI-1) concentrations in hypercholesterolemic subjects.
Journal: Lipids in health and disease 20070101
Title: Medicinal importance of grapefruit juice and its interaction with various drugs.
Journal: Nutrition journal 20070101
Title: Inhibition of cell motility by troglitazone in human ovarian carcinoma cell line.
Journal: BMC cancer 20070101
Title: Manipulation of hedgehog signaling in Xenopus by means of embryo microinjection and application of chemical inhibitors.
Journal: Methods in molecular biology (Clifton, N.J.) 20070101
Title: The Ontario printed educational message (OPEM) trial to narrow the evidence-practice gap with respect to prescribing practices of general and family physicians: a cluster randomized controlled trial, targeting the care of individuals with diabetes and hypertension in Ontario, Canada.
Journal: Implementation science : IS 20070101
Title: Antihyperlipemic and antihypertensive effects of Spirulina maxima in an open sample of Mexican population: a preliminary report.
Journal: Lipids in health and disease 20070101
Title: A critical gap between recommended and achieved LDL-cholesterol levels. Results of statin therapy in Slovakia.
Journal: Bratislavske lekarske listy 20070101
Title: Peroxisome proliferator-activated receptors in lung cancer.
Journal: PPAR research 20070101
Title: Effect of Coenzyme Q10 and green tea on plasma and liver lipids, platelet aggregation, TBARS production and erythrocyte Na leak in simvastatin treated hypercholesterolmic rats.
Journal: Nutrition research and practice 20070101
Title: Elevated K-ras activity with cholestyramine and lovastatin, but not konjac mannan or niacin in lung--importance of mouse strain.
Journal: Biochemical pharmacology 20061215
Title: Cholesterol depletion reduces serotonin binding and signaling via human 5-HT(7(a)) receptors.
Journal: European journal of pharmacology 20061215
Title: Upregulation of p27 and its inhibition of CDK2/cyclin E activity following DNA damage by a novel platinum agent are dependent on the expression of p21.
Journal: British journal of cancer 20061204
Title: Osteogenic gene expression decreases in stromal cells of patients with osteonecrosis.
Journal: Clinical orthopaedics and related research 20061201
Title: Colchicine and HMG Co-A reductase inhibitors induced myopathy-a case report.
Journal: Neurotoxicology 20061201
Title: Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide.
Journal: British journal of pharmacology 20061201
Title: Berberine, a natural cholesterol reducing product, exerts antitumor cytostatic/cytotoxic effects independently from the mevalonate pathway.
Journal: Oncology reports 20061201
Title: Lovastatin possesses a fungistatic effect against Candida albicans, but does not trigger apoptosis in this opportunistic human pathogen.
Journal: FEMS yeast research 20061201
Title: Chemopreventive agents alters global gene expression pattern: predicting their mode of action and targets.
Journal: Current cancer drug targets 20061201
Title: Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance.
Journal: Clinical pharmacology and therapeutics 20061201
Title: Regulation of hepatic cholesterol metabolism in CETP/LDLr mice by cholesterol feeding and by drugs (cholestyramine and lovastatin) that lower plasma cholesterol.
Journal: Clinical and experimental pharmacology & physiology 20061201
Title: Molecular diagnosis of a BRAF papillary thyroid carcinoma with multiple chromosome abnormalities and rare adrenal and hypothalamic metastases.
Journal: Thyroid : official journal of the American Thyroid Association 20061201
Title: Lipid lowering inefficacy of high-dose statin therapy due to concurrent use of phenytoin.
Journal: Southern medical journal 20061201
Title: Who should receive a statin drug to lower cardiovascular risk? Does the drug and the dose of the drug matter?
Journal: Vascular health and risk management 20061201
Title: Phenotypic conversion leads to structural and functional changes of smooth muscle sarcolemma.
Journal: Experimental cell research 20061101
Title: HMG-CoA reductase inhibitors inhibit rat propylthiouracil-induced goiter by modulating the ras-MAPK pathway.
Journal: Journal of molecular medicine (Berlin, Germany) 20061101
Title: Direct demonstration of an antiinflammatory effect of simvastatin in subjects with the metabolic syndrome.
Journal: The Journal of clinical endocrinology and metabolism 20061101
Title: Plasma cholesterol is hyperresponsive to statin in ABCG5/ABCG8 transgenic mice.
Journal: Hepatology (Baltimore, Md.) 20061101
Title: Role of P-glycoprotein in statin drug interactions.
Journal: Pharmacotherapy 20061101
Title: Statins, fibrates, and melanoma risk: a systematic review and meta-analysis.
Journal: Journal of the National Cancer Institute 20061101
Title: Biosynthesis of lovastatin analogs with a broadly specific acyltransferase.
Journal: Chemistry & biology 20061101
Title: Distribution of lovastatin to bone and its effect on bone turnover in rats.
Journal: The Journal of pharmacy and pharmacology 20061101
Title: Statins inhibit the dimerization of beta-secretase via both isoprenoid- and cholesterol-mediated mechanisms.
Journal: The Biochemical journal 20061015
Title: Monascus fermentation of dioscorea for increasing the production of cholesterol-lowering agent--monacolin K and antiinflammation agent--monascin.
Journal: Applied microbiology and biotechnology 20061001
Title: Influence of cholesterol and lovastatin on alpha-form of secreted amyloid precursor protein and expression of alpha7 nicotinic receptor on astrocytes.
Journal: Neurochemistry international 20061001
Title: Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions.
Journal: Pharmacology & therapeutics 20061001
Title: Neopterin induces pro-atherothrombotic phenotype in human coronary endothelial cells.
Journal: Journal of thrombosis and haemostasis : JTH 20061001
Title: Depletion of substrates for protein prenylation increases apoptosis in human periovulatory granulosa cells.
Journal: Molecular reproduction and development 20061001
Title: The role of geranylgeranylated proteins in human mesangial cell proliferation.
Journal: Kidney international 20061001
Title: Mevastatin inhibits proliferation of rat ovarian theca-interstitial cells by blocking the mitogen-activated protein kinase pathway.
Journal: Fertility and sterility 20061001
Title: Cost efficiency and formulary considerations for statin therapy.
Journal: The American journal of managed care 20061001
Title: Neuropeptides induced a pronounced and statin-sensitive dysregulation of mevalonate cycle in human monocytes of patients with hypercholesterolemia.
Journal: Neuropeptides 20061001
Title: MUBs, a family of ubiquitin-fold proteins that are plasma membrane-anchored by prenylation.
Journal: The Journal of biological chemistry 20060915
Title: An automated blood sampling system to measure lovastatin level in plasma and faeces.
Journal: Biomedical chromatography : BMC 20060901
Title: The key role of apoptosis in the pathogenesis and treatment of pulmonary hypertension.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20060901
Title: Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis.
Journal: The American journal of pathology 20060901
Title: Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin.
Journal: The Journal of clinical investigation 20060901
Title: Differential efficacy of 3-hydroxy-3-methylglutaryl CoA reductase inhibitors on the cell cycle of prostate cancer cells.
Journal: Molecular cancer therapeutics 20060901
Title: Stimulation of an alpha1-adrenergic receptor downregulates ecto-5' nucleotidase activity on the apical membrane of RPE cells.
Journal: Purinergic signalling 20060901
Title: Proteomic analysis of Caco-2 cells treated with monacolin K.
Journal: Journal of agricultural and food chemistry 20060823
Title: Compound heterozygosity for mutations in LMNA causes a progeria syndrome without prelamin A accumulation.
Journal: Human molecular genetics 20060815
Title: Herbicidal effects of statin pharmaceuticals in Lemna gibba.
Journal: Environmental science & technology 20060815
Title: Roles of endogenously synthesized sterols in the endocytic pathway.
Journal: The Journal of biological chemistry 20060811
Title: Cholesterol deficiency perturbs actin signaling and glutamate homeostasis in hippocampal astrocytes.
Journal: Brain research 20060809
Title: Screening of compactin-resistant microorganisms capable of converting compactin to pravastatin.
Journal: Current microbiology 20060801
Title: Clinical inquiries. Which medications can be split without compromising efficacy and safety?
Journal: The Journal of family practice 20060801
Title: Effect of red mold rice supplements on serum and meat cholesterol levels of broilers chicken.
Journal: Applied microbiology and biotechnology 20060801
Title: Statins in the treatment of chronic heart failure: a systematic review.
Journal: PLoS medicine 20060801
Title: Statins, especially atorvastatin, may improve survival following brachytherapy for clinically localized prostate cancer.
Journal: Urologic nursing 20060801
Title: [Protective effect of effective parts of Zingiber Offecinal on vascular endothelium of the experimental hyperlipidemic rats].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060801
Title: Strategies to enhance epidermal growth factor inhibition: targeting the mevalonate pathway.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060715
Title: Alzheimer-like plaque formation by human macrophages is reduced by fibrillation inhibitors and lovastatin.
Journal: Journal of molecular biology 20060707
Title: Inhibitory effects of statins on human monocarboxylate transporter 4.
Journal: International journal of pharmaceutics 20060706
Title: Statins revert doxorubicin resistance via nitric oxide in malignant mesothelioma.
Journal: International journal of cancer 20060701
Title: A comparative study on the antimutagenicity of atorvastatin and lovastatin against directly acting mutagens.
Journal: Cell biology and toxicology 20060701
Title: Statins reduce human blood-brain barrier permeability and restrict leukocyte migration: relevance to multiple sclerosis.
Journal: Annals of neurology 20060701
Title: Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis.
Journal: Biochimica et biophysica acta 20060701
Title: Lovastatin-induced apoptosis in macrophages through the Rac1/Cdc42/JNK pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20060701
Title: Cyclodextrins but not compactin inhibit the lateral diffusion of membrane proteins independent of cholesterol.
Journal: Traffic (Copenhagen, Denmark) 20060701
Title: Different anti-HCV profiles of statins and their potential for combination therapy with interferon.
Journal: Hepatology (Baltimore, Md.) 20060701
Title: Persistence and adherence to cholesterol lowering agents: evidence from Régie de l'Assurance Maladie du Québec data.
Journal: American heart journal 20060701
Title: Lovastatin modulates increased cholesterol and oxysterol levels and has a neuroprotective effect on rat hippocampal neurons after kainate injury.
Journal: Journal of neuropathology and experimental neurology 20060701
Title: Study on the conversion of three natural statins from lactone forms to their corresponding hydroxy acid forms and their determination in Pu-Erh tea.
Journal: Journal of chromatography. A 20060630
Title: Peroxisomal cholesterol biosynthesis and Smith-Lemli-Opitz syndrome.
Journal: Biochemical and biophysical research communications 20060623
Title: Lovastatin enhances clearance of apoptotic cells (efferocytosis) with implications for chronic obstructive pulmonary disease.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20060615
Title: Mitomycin C induces apoptosis via Fas/FasL dependent pathway and suppression of IL-18 in cervical carcinoma cells.
Journal: Cancer letters 20060608
Title: Effects of the sporulation conditions on the lovastatin production by Aspergillus terreus.
Journal: Bioprocess and biosystems engineering 20060601
Title: Polyamine depletion and cell cycle manipulation in combination with HSV thymidine kinase/ganciclovir cancer gene therapy.
Journal: International journal of oncology 20060601
Title: Randomized comparative study of the effects of treatment with once-daily, niacin extended-release/lovastatin and with simvastatin on lipid profile and fibrinolytic parameters in Taiwan.
Journal: The Kaohsiung journal of medical sciences 20060601
Title: Repression of secondary metabolite production by exogenous cAMP in Monascus.
Journal: Bioscience, biotechnology, and biochemistry 20060601
Title: Rosuvastatin 5 and 10 mg/d: a pilot study of the effects in hypercholesterolemic adults unable to tolerate other statins and reach LDL cholesterol goals with nonstatin lipid-lowering therapies.
Journal: Clinical therapeutics 20060601
Title: Lipoprotein-associated phospholipase A2, vascular inflammation and cardiovascular risk prediction.
Journal: Vascular health and risk management 20060601
Title: Plant sterols as dietary adjuvants in the reduction of cardiovascular risk: theory and evidence.
Journal: Vascular health and risk management 20060601
Title: Fenofibrate: a novel formulation (Triglide) in the treatment of lipid disorders: a review.
Journal: International journal of nanomedicine 20060601
Title: Statin use and breast cancer: prospective results from the Women's Health Initiative.
Journal: Journal of the National Cancer Institute 20060517
Title: Increased PTEN expression due to transcriptional activation of PPARgamma by Lovastatin and Rosiglitazone.
Journal: International journal of cancer 20060515
Title: Tissue-specific effects of statins on the expression of heme oxygenase-1 in vivo.
Journal: Biochemical and biophysical research communications 20060512
Title: Statins and stroke: current clinical practice.
Journal: Stroke 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Effect of statins on platelet PAR-1 thrombin receptor in patients with the metabolic syndrome (from the PAR-1 inhibition by statins [PARIS] study).
Journal: The American journal of cardiology 20060501
Title: Moderate alcohol consumption and safety of lovastatin and warfarin among men: the post-coronary artery bypass graft trial.
Journal: The American journal of medicine 20060501
Title: The quantification of monacolin K in some red yeast rice from Fujian province and the comparison of the other product.
Journal: Chemical & pharmaceutical bulletin 20060501
Title: Effects of the principal nutrients on lovastatin production by Monascus pilosus.
Journal: Bioscience, biotechnology, and biochemistry 20060501
Title: Is atorvastatin superior to other statins? Analysis of the clinical trials with atorvastatin having cardiovascular endpoints.
Journal: Reviews on recent clinical trials 20060501
Title: Statin safety and drug interactions: clinical implications.
Journal: The American journal of cardiology 20060417
Title: Statin safety: a systematic review.
Journal: The American journal of cardiology 20060417
Title: Proapoptotic and antitumor activities of the HMG-CoA reductase inhibitor, lovastatin, against Dalton's lymphoma ascites tumor in mice.
Journal: Clinica chimica acta; international journal of clinical chemistry 20060401
Title: Lovastatin and thalidomide have a combined effect on the rate of multiple myeloma cell apoptosis in short term cell cultures.
Journal: European journal of clinical pharmacology 20060401
Title: The influence of co-treatment with carbamazepine, amiodarone and statins on warfarin metabolism and maintenance dose.
Journal: European journal of clinical pharmacology 20060401
Title: Effect of rosuvastatin compared with other statins on lipid levels and National Cholesterol Education Program goal attainment for low-density lipoprotein cholesterol in a usual care setting.
Journal: Pharmacotherapy 20060401
Title: Genetically determined apo B levels and peak LDL density predict angiographic response to intensive lipid-lowering therapy.
Journal: Journal of internal medicine 20060401
Title: Retrospective review of sex differences in the management of dyslipidemia in coronary heart disease: an analysis of patient data from a Maryland-based health maintenance organization.
Journal: Clinical therapeutics 20060401
Title: The beneficial in vitro effects of lovastatin and chelerythrine on relaxatory response to acetylcholine in the perfused mesentric bed isolated from diabetic rats.
Journal: European journal of pharmacology 20060327
Title: Potential impact on cardiovascular public health of over-the-counter statin availability.
Journal: The American journal of cardiology 20060315
Title: Analysis of five HMG-CoA reductase inhibitors-- atorvastatin, lovastatin, pravastatin, rosuvastatin and simvastatin: pharmacological, pharmacokinetic and analytical overview and development of a new method for use in pharmaceutical formulations analysis and in vitro metabolism studies.
Journal: Biomedical chromatography : BMC 20060301
Title: Comparative evaluation of HERG currents and QT intervals following challenge with suspected torsadogenic and nontorsadogenic drugs.
Journal: The Journal of pharmacology and experimental therapeutics 20060301
Title: Effects of acid and lactone forms of eight HMG-CoA reductase inhibitors on CYP-mediated metabolism and MDR1-mediated transport.
Journal: Pharmaceutical research 20060301
Title: HMG-CoA reductase inhibitors induce apoptosis in pericytes.
Journal: Microvascular research 20060301
Title: Effects of various statins on cytokine-dependent growth and IgE-dependent release of histamine in human mast cells.
Journal: Allergy 20060301
Title: Coxiella burnetii inhabits a cholesterol-rich vacuole and influences cellular cholesterol metabolism.
Journal: Cellular microbiology 20060301
Title: Evidence-based prescribing of statins: a developing world perspective.
Journal: PLoS medicine 20060301
Title: Exenatide.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060301
Title: Low high-density lipoprotein cholesterol and cardiovascular disease: risk reduction with statin therapy.
Journal: American heart journal 20060301
Title: N6-isopentenyladenosine arrests tumor cell proliferation by inhibiting farnesyl diphosphate synthase and protein prenylation.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301
Title: Hydroxymethylglutaryl-CoA reductase inhibitors in older persons with acute myocardial infarction: evidence for an age-statin interaction.
Journal: Journal of the American Geriatrics Society 20060301
Title: Inhibitory effect of Magnolia officinalis and lovastatin on aortic oxidative stress and apoptosis in hyperlipidemic rabbits.
Journal: Journal of cardiovascular pharmacology 20060301
Title: Processing of amyloid precursor protein as a biochemical link between atherosclerosis and Alzheimer's disease.
Journal: Cardiovascular & hematological disorders drug targets 20060301
Title: [Lowering plasma homocysteine with vitamins B6, B12, and folic acid. Effect on lipids concentration in patients with secondary hyperlipoproteinemia type IV, with and without Lovastatina treatment].
Journal: Archivos latinoamericanos de nutricion 20060301
Title: Complementary therapy to target LDL cholesterol: the role of the ezetimibe/simvastatin combination.
Journal: Vascular health and risk management 20060301
Title: Evaluation of efficacy and safety of fixed dose lovastatin and niacin(ER) combination in asian Indian dyslipidemic patients: a multicentric study.
Journal: Vascular health and risk management 20060301
Title: Dietary approaches that delay age-related diseases.
Journal: Clinical interventions in aging 20060301
Title: Telithromycin in the treatment of acute bacterial sinusitis, acute exacerbations of chronic bronchitis, and community-acquired pneumonia.
Journal: Therapeutics and clinical risk management 20060301
Title: Formal enantioselective synthesis of (+)-compactin.
Journal: Organic letters 20060216
Title: Statins induce calcium-dependent mitochondrial permeability transition.
Journal: Toxicology 20060215
Title: Dramatic synergistic anticancer effect of clinically achievable doses of lovastatin and troglitazone.
Journal: International journal of cancer 20060201
Title: The prion protein requires cholesterol for cell surface localization.
Journal: Molecular and cellular neurosciences 20060201
Title: Rho/ROCK pathway as a target of tumor therapy.
Journal: Journal of neuroscience research 20060201
Title: Activators of the energy sensing kinase AMPK inhibit random cell movement and chemotaxis in U937 cells.
Journal: Immunology and cell biology 20060201
Title: Alcohol consumption, atherosclerotic progression, and prognosis among patients with coronary artery bypass grafts.
Journal: American heart journal 20060201
Title: The influence of cholesterol and lipid metabolism on host cell structure and hepatitis C virus replication.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201
Title: Lovastatin protects human endothelial cells from killing by ionizing radiation without impairing induction and repair of DNA double-strand breaks.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060201
Title: Lovastatin reduces apoptosis and downregulates the CD40 expression induced by TNF-alpha in cerebral vascular endothelial cells.
Journal: Current neurovascular research 20060201
Title: Kinetics and mechanisms of cholesterol esterase inhibition by cardiovascular drugs in vitro.
Journal: Indian journal of biochemistry & biophysics 20060201
Title: Lovastatin-induced RhoA modulation and its effect on senescence in prostate cancer cells.
Journal: Biochemical and biophysical research communications 20060120
Title: Alkylamines cause Vgamma9Vdelta2 T-cell activation and proliferation by inhibiting the mevalonate pathway.
Journal: Blood 20060115
Title: Farnesyl and geranylgeranyl transferase inhibitors induce G1 arrest by targeting the proteasome.
Journal: Cancer research 20060115
Title: Pharmacodynamic effects of high dose lovastatin in subjects with advanced malignancies.
Journal: Cancer chemotherapy and pharmacology 20060101
Title: Erythropoietin receptor signal transduction requires protein geranylgeranylation.
Journal: The Journal of pharmacology and experimental therapeutics 20060101
Title: HMG-CoA reductase inhibitors upregulate heme oxygenase-1 expression in murine RAW264.7 macrophages via ERK, p38 MAPK and protein kinase G pathways.
Journal: Cellular signalling 20060101
Title: Cleavage of focal adhesion proteins and PKCdelta during lovastatin-induced apoptosis in spontaneously immortalized rat brain neuroblasts.
Journal: The FEBS journal 20060101
Title: Statins and osteoporosis: new role for old drugs.
Journal: The Journal of pharmacy and pharmacology 20060101
Title: Effects of garlic oil on postmenopausal osteoporosis using ovariectomized rats: comparison with the effects of lovastatin and 17beta-estradiol.
Journal: Phytotherapy research : PTR 20060101
Title: Statins decrease serotonin-induced contractions in coronary arteries of swine in vitro.
Journal: Pharmacology 20060101
Title: Increased therapeutic potential of an experimental anti-mitotic inhibitor SB715992 by genistein in PC-3 human prostate cancer cell line.
Journal: BMC cancer 20060101
Title: Statin wars following coronary revascularization--evidence-based clinical practice?
Journal: The Canadian journal of cardiology 20060101
Title: New treatment strategies for multiple myeloma by targeting BCL-2 and the mevalonate pathway.
Journal: Current pharmaceutical design 20060101
Title: Statin-related adverse events: a meta-analysis.
Journal: Clinical therapeutics 20060101
Title: Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells.
Journal: Molecular cancer 20060101
Title: Farnesylation or geranylgeranylation? Efficient assays for testing protein prenylation in vitro and in vivo.
Journal: BMC biochemistry 20060101
Title: [Correction of thrombocyte-vascular hemostasis in metabolic syndrome].
Journal: Klinicheskaia meditsina 20060101
Title: Fluvastatin does not elevate periosteal osteogenesis induce by Moloney sarcoma virus (MSV) in mice.
Journal: Pharmacological reports : PR 20060101
Title: Guinea pigs: a suitable animal model to study lipoprotein metabolism, atherosclerosis and inflammation.
Journal: Nutrition & metabolism 20060101
Title: Action of Lovastatin (Mevinolin) on an in vitro model of angiogenesis and its co-culture with malignant melanoma cell lines.
Journal: Cancer cell international 20060101
Title: Lovastatin production by Pleurotus ostreatus: effects of the C:N ratio.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20060101
Title: Inhibition of NF-kappaB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia.
Journal: Journal of neuroinflammation 20060101
Title: Mevalonate kinase deficiencies: from mevalonic aciduria to hyperimmunoglobulinemia D syndrome.
Journal: Orphanet journal of rare diseases 20060101
Title: A randomized trial to assess the impact of opinion leader endorsed evidence summaries on the use of secondary prevention strategies in patients with coronary artery disease: the ESP-CAD trial protocol [NCT00175240].
Journal: Implementation science : IS 20060101
Title: Transdermal application of lovastatin to rats causes profound increases in bone formation and plasma concentrations.
Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20060101
Title: Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts.
Journal: Arthritis research & therapy 20060101
Title: Cholesterol distribution, not total levels, correlate with altered amyloid precursor protein processing in statin-treated mice.
Journal: Neuromolecular medicine 20060101
Title: Cost-effectiveness analysis of cholesterol-lowering therapies in Spain.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101
Title: Synchronous analysis method for detection of citrinin and the lactone and acid forms of monacolin K in red mold rice.
Journal: Journal of AOAC International 20060101
Title: Comparison between mevinolin and PTH action on MG63 osteoblast-like cells.
Journal: Biomedical sciences instrumentation 20060101
Title: Adherence and persistence with single-dosage form extended-release niacin/lovastatin compared with statins alone or in combination with extended-release niacin.
Journal: The Annals of pharmacotherapy 20060101
Title: Statin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis.
Journal: Arthritis research & therapy 20060101
Title: Safety issues with statin therapy.
Journal: Journal of the American Pharmacists Association : JAPhA 20060101
Title: Coronary heart disease policy models: a systematic review.
Journal: BMC public health 20060101
Title: A long-term study of dyslipidemia and dyslipoproteinemia in stable post-renal transplant patients.
Journal: Renal failure 20060101
Title: Roles of cholesterol and lipids in the etiopathogenesis of Alzheimer's disease.
Journal: Journal of biomedicine & biotechnology 20060101
Title: Dendritic cell-mediated HIV-1 transmission to T cells of LAD-1 patients is impaired due to the defect in LFA-1.
Journal: Retrovirology 20060101
Title: Statins, bugs and prophylaxis: intriguing possibilities.
Journal: Critical care (London, England) 20060101
Title: Chinese red yeast rice (Monascus purpureus) for primary hyperlipidemia: a meta-analysis of randomized controlled trials.
Journal: Chinese medicine 20060101
Title: Determination by chromatographic methods of selected medicines reducing the level of cholesterol.
Journal: Acta poloniae pharmaceutica 20060101
Title: Effect of Monascus purpureus-fermented rice on lipidemia and fatty liver in quail.
Journal: Research communications in molecular pathology and pharmacology 20060101
Title: [A short-term effect of lovastatin on lipoprotein metabolism in patients with cerebrovascular lesions concomitant with diabetes mellitus II type].
Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101
Title: Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation.
Journal: The Journal of biological chemistry 20051216
Title: Implications from the Air Force/Texas Coronary Atherosclerosis Prevention Study for the Adult Treatment Panel III guidelines.
Journal: The American journal of cardiology 20051215
Title: Statins prevent beta-amyloid inhibition of sympathetic alpha7-nAChR-mediated nitrergic neurogenic dilation in porcine basilar arteries.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20051201
Title: Lovastatin stimulates p75 TNF receptor (TNFR2) expression in primary human endothelial cells.
Journal: International journal of molecular medicine 20051201
Title: Plasma clearance of lovastatin versus chinese red yeast rice in healthy volunteers.
Journal: Journal of alternative and complementary medicine (New York, N.Y.) 20051201
Title: Lovastatin reduces neuronal cell death in hippocampal CA1 subfield after pilocarpine-induced status epilepticus: preliminary results.
Journal: Arquivos de neuro-psiquiatria 20051201
Title: Extracts of Monascusus purpureus beyond statins--profile of efficacy and safety of the use of extracts of Monascus purpureus.
Journal: Chinese journal of integrative medicine 20051201
Title: [Fluvastatin-induced dermatomyositis].
Journal: Annales de dermatologie et de venereologie 20051201
Title: Replication of Coxiella burnetii is inhibited in CHO K-1 cells treated with inhibitors of cholesterol metabolism.
Journal: Annals of the New York Academy of Sciences 20051201
Title: Optimal lipid modification: the rationale for combination therapy.
Journal: Vascular health and risk management 20051201
Title: Efficacy and safety of atorvastatin in South Asian patients with dyslipidemia: an open label noncomparative pilot study.
Journal: Vascular health and risk management 20051201
Title: Are statins being underdosed in clinical practice? Data from TACTICS-TIMI 18.
Journal: Critical pathways in cardiology 20051201
Title: Safety and tolerability of oral antifungal agents in the treatment of fungal nail disease: a proven reality.
Journal: Therapeutics and clinical risk management 20051201
Title: INSIG: a broadly conserved transmembrane chaperone for sterol-sensing domain proteins.
Journal: The EMBO journal 20051116
Title: Lovastatin stimulates up-regulation of alpha7 nicotinic receptors in cultured neurons without cholesterol dependency, a mechanism involving production of the alpha-form of secreted amyloid precursor protein.
Journal: Journal of neuroscience research 20051115
Title: The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1.
Journal: Current biology : CB 20051108
Title: The effect of six different statins on the proliferation, migration, and invasion of human smooth muscle cells.
Journal: The Journal of surgical research 20051101
Title: Pregnancy outcomes after maternal exposure to simvastatin and lovastatin.
Journal: Birth defects research. Part A, Clinical and molecular teratology 20051101
Title: Optimal goals for statin use in patients with coronary artery disease.
Journal: Current opinion in cardiology 20051101
Title: PAF-receptor antagonists, lovastatin, and the PTK inhibitor genistein inhibit H2O2 secretion by macrophages cultured on oxidized-LDL matrices.
Journal: Journal of leukocyte biology 20051101
Title: Experience with statin use in patients with chronic hepatitis C infection.
Journal: The American journal of cardiology 20051101
Title: X-Hitting: an algorithm for novelty detection and dereplication by UV spectra of complex mixtures of natural products.
Journal: Analytical chemistry 20051101
Title: Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment.
Journal: Cellular and molecular life sciences : CMLS 20051101
Title: The effect of switching on compliance and persistence: the case of statin treatment.
Journal: The American journal of managed care 20051101
Title: Pharmacokinetic interactions of the oral renin inhibitor aliskiren with lovastatin, atenolol, celecoxib and cimetidine.
Journal: International journal of clinical pharmacology and therapeutics 20051101
Title: Safety of statins: effects on muscle and the liver.
Journal: Cleveland Clinic journal of medicine 20051101
Title: The benefits of statin therapy--what questions remain?
Journal: Clinical cardiology 20051101
Title: Statins and fibrates for preventing melanoma.
Journal: The Cochrane database of systematic reviews 20051019
Title: Calmodulin binding to the small GTPase Ral requires isoprenylated Ral.
Journal: Biochemical and biophysical research communications 20051014
Title: Evaluation of the anti-HIV activity of statins.
Journal: AIDS (London, England) 20051014
Title: Hypolipidaemic and antioxidant effect of Enicostemma littorale Blume aqueous extract in cholesterol fed rats.
Journal: Journal of ethnopharmacology 20051003
Title: Cholesterol biosynthesis and the pro-apoptotic effects of the p75 nerve growth factor receptor in PC12 pheochromocytoma cells.
Journal: Brain research. Molecular brain research 20051003
Title: In vitro effect of statins on cytokine production and mitogen response of human peripheral blood mononuclear cells.
Journal: Clinical immunology (Orlando, Fla.) 20051001
Title: Persistence and determinants of statin therapy among middle-aged patients free of cardiovascular disease.
Journal: European journal of clinical pharmacology 20051001
Title: Differential association between statin exposure and elevated levels of creatine kinase.
Journal: The Annals of pharmacotherapy 20051001
Title: Clinical and economic outcomes of conversion of simvastatin to lovastatin in a group-model health maintenance organization.
Journal: Journal of managed care pharmacy : JMCP 20051001
Title: Tobacco BY-2 cells expressing fission yeast cdc25 bypass a G2/M block on the cell cycle.
Journal: The Plant journal : for cell and molecular biology 20051001
Title: The association between RhoB and caspase-2: changes with lovastatin-induced apoptosis.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20051001
Title: Statins modulate the levels of osteoprotegerin/receptor activator of NFkappaB ligand mRNA in mouse bone-cell cultures.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20051001
Title: Grape fruit juice-drug interactions.
Journal: Pakistan journal of pharmaceutical sciences 20051001
Title: [Hypolipidemic treatment under special conditions: posttransplant and/or immunosuppressive therapy].
Journal: Arquivos brasileiros de cardiologia 20051001
Title: Study on red fermented rice with high concentration of monacolin K and low concentration of citrinin.
Journal: International journal of food microbiology 20050915
Title: Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil.
Journal: Journal of molecular biology 20050909
Title: Review of primary and secondary prevention trials with lovastatin, pravastatin, and simvastatin.
Journal: The American journal of cardiology 20050905
Title: Lovastatin inhibits the growth and survival pathway of phosphoinositide 3-kinase/protein kinase B in immortalized rat brain neuroblasts.
Journal: Journal of neurochemistry 20050901
Title: HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050901
Title: The pharmacological potential of mushrooms.
Journal: Evidence-based complementary and alternative medicine : eCAM 20050901
Title: Efficacy and safety of lovastatin therapy in adolescent girls with heterozygous familial hypercholesterolemia.
Journal: Pediatrics 20050901
Title: Lovastatin reduces nuclear factor kappaB activation induced by C-reactive protein in human vascular endothelial cells.
Journal: Biological & pharmaceutical bulletin 20050901
Title: Combining prenylation inhibitors causes synergistic cytotoxicity, apoptosis and disruption of RAS-to-MAP kinase signalling in multiple myeloma cells.
Journal: British journal of haematology 20050901
Title: Successful conversion of patients with hypercholesterolemia from a brand name to a generic cholesterol-lowering drug.
Journal: The American journal of managed care 20050901
Title: Lovastatin suppresses invasiveness of anaplastic thyroid cancer cells by inhibiting Rho geranylgeranylation and RhoA/ROCK signaling.
Journal: Endocrine-related cancer 20050901
Title: Regulation of connexin expression after balloon injury: possible mechanisms for antiproliferative effect of statins.
Journal: American journal of hypertension 20050901
Title: Fluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells.
Journal: British journal of cancer 20050808
Title: Leukocyte function-associated antigen 1-mediated adhesion stability is dynamically regulated through affinity and valency during bond formation with intercellular adhesion molecule-1.
Journal: The Journal of biological chemistry 20050805
Title: Lovastatin-induced PC-12 cell differentiation is associated with RhoA/RhoA kinase pathway inactivation.
Journal: Molecular and cellular neurosciences 20050801
Title: Genomic effect of vitamin 'C' and statins within human mononuclear cells involved in atherogenic process.
Journal: European journal of clinical nutrition 20050801
Title: Lipoprotein-associated phospholipase A2 as a target of therapy.
Journal: Current opinion in lipidology 20050801
Title: Comparison of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) as inhibitors of cytochrome P450 2C8.
Journal: Basic & clinical pharmacology & toxicology 20050801
Title: The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, lovastatin (statin) ameliorates CCK-induced acute pancreatitis in rats.
Journal: Biological & pharmaceutical bulletin 20050801
Title: Evolutionary relationships among Aspergillus terreus isolates and their relatives.
Journal: Antonie van Leeuwenhoek 20050801
Title: Statin-induced blockade of prenylation alters nucleocytoplasmic shuttling of GTP-binding proteins gamma2 and beta2 and enhances their suppressive effect on glucocorticoid receptor transcriptional activity.
Journal: European journal of clinical investigation 20050801
Title: Polar body formation in Spisula oocytes: function of the peripheral aster.
Journal: The Biological bulletin 20050801
Title: [Effect of Laminaria japonica polysaccharides on lowing serum lipid and anti-atherosclerosis in hyperlipemia quails].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050801
Title: Natural insights for chemical biologists.
Journal: Nature chemical biology 20050801
Title: Risks of a nonprescription lovastatin.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050715
Title: Association between short-term effectiveness of statins and long-term adherence to lipid-lowering therapy.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050715
Title: Induction of macrophage elastase (MMP-12) gene expression by statins.
Journal: Journal of cellular physiology 20050701
Title: Direct comparison of dietary portfolio vs statin on C-reactive protein.
Journal: European journal of clinical nutrition 20050701
Title: Inhibition of phosphoinositide 3 kinase-Akt (protein kinase B)-nuclear factor-kappa B pathway by lovastatin limits endothelial-monocyte cell interaction.
Journal: Journal of neurochemistry 20050701
Title: Low high-density lipoprotein cholesterol disorders and cardiovascular risk: contribution of associated low-density lipoprotein subclass abnormalities.
Journal: Current opinion in cardiology 20050701
Title: Cholesterol levels and statin use in patients with coronary heart disease treated in primary care settings.
Journal: Preventing chronic disease 20050701
Title: Effects of cholesterol-lowering statins on the aqueous humor outflow pathway.
Journal: Investigative ophthalmology & visual science 20050701
Title: In vivo and in vitro effects of statins on lymphocytes in patients with Hashimoto's thyroiditis.
Journal: European journal of endocrinology 20050701
Title: JBMR anniversary classic. Nitrogen-containing biophosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. Originally published in Volume 7, number 4, pp 581-9 (1998).
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20050701
Title: Gestational exposure to lovastatin followed by cardiac malformation misclassified as holoprosencephaly.
Journal: The New England journal of medicine 20050630
Title: Degradation of HMG-CoA reductase in rat liver is cholesterol and ubiquitin independent.
Journal: FEBS letters 20050606
Title: Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities.
Journal: Journal of lipid research 20050601
Title: Statin drugs and congenital anomalies.
Journal: American journal of medical genetics. Part A 20050601
Title: Relation of progression of coronary artery atherosclerosis to risk of cardiovascular events (from the Monitored Atherosclerosis Regression Study).
Journal: The American journal of cardiology 20050601
Title: A promoter polymorphism in cholesterol 7alpha-hydroxylase interacts with apolipoprotein E genotype in the LDL-lowering response to atorvastatin.
Journal: Atherosclerosis 20050601
Title: The effect of simvastatin on the proliferation and differentiation of human bone marrow stromal cells.
Journal: Journal of Korean medical science 20050601
Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.
Journal: Chemical research in toxicology 20050601
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20050601
Title: 4,8-Dimethyldecanal, the aggregation pheromone of Tribolium castaneum, is biosynthesized through the fatty acid pathway.
Journal: Journal of chemical ecology 20050601
Title: A new paradigm of cardiovascular risk factor modification.
Journal: Vascular health and risk management 20050601
Title: PKCalpha is involved in phorbol ester TPA-mediated stabilization of p14ARF.
Journal: Biochemical and biophysical research communications 20050520
Title: Remote asymmetric induction in an intramolecular ionic Diels-Alder reaction: application to the total synthesis of (+)-dihydrocompactin.
Journal: Journal of the American Chemical Society 20050511
Title: HMG CoA reductase inhibitors (statins) to treat Epstein-Barr virus-driven lymphoma.
Journal: British journal of cancer 20050509
Title: Statins activate the mitochondrial pathway of apoptosis in human lymphoblasts and myeloma cells.
Journal: Carcinogenesis 20050501
Title: Hepatic uptake of the novel antifungal agent caspofungin.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050501
Title: The sterol response element binding protein regulates cyclooxygenase-2 gene expression in endothelial cells.
Journal: Journal of lipid research 20050501
Title: Interleukin-6 and mevastatin regulate plasminogen activator inhibitor-1 through CCAAT/enhancer-binding protein-delta.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20050501
Title: Lovastatin alters the isoprenoid biosynthetic pathway in acute myelogenous leukemia cells in vivo.
Journal: Leukemia research 20050501
Title: Effects of atorvastatin versus other statins on fasting and postprandial C-reactive protein and lipoprotein-associated phospholipase A2 in patients with coronary heart disease versus control subjects.
Journal: The American journal of cardiology 20050501
Title: Ascorbate depletion: a critical step in nickel carcinogenesis?
Journal: Environmental health perspectives 20050501
Title: A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the ezetimibe add-on to statin for effectiveness (EASE) trial.
Journal: Mayo Clinic proceedings 20050501
Title: National trends in statin use by coronary heart disease risk category.
Journal: PLoS medicine 20050501
Title: [Hypothyroidism and lovastatin-induced myositis].
Journal: Anales de medicina interna (Madrid, Spain : 1984) 20050501
Title: Statins reduce connexin40 and connexin43 expression in atherosclerotic aorta of rabbits.
Journal: International journal of cardiology 20050428
Title: Effectiveness of statins for secondary prevention in elderly patients after acute myocardial infarction: an evaluation of class effect.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050426
Title: Frequency of myopathy in patients receiving lovastatin.
Journal: The American journal of cardiology 20050415
Title: Statins potentiate the IFN-gamma-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells.
Journal: Biochimica et biophysica acta 20050415
Title: Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050401
Title: Projected coronary heart disease risk benefit with ezetimibe.
Journal: Atherosclerosis 20050401
Title: Measurement of saturable and non-saturable components of anandamide uptake into P19 embryonic carcinoma cells in the presence of fatty acid-free bovine serum albumin.
Journal: Chemistry and physics of lipids 20050401
Title: Post-translational processing of beta-secretase in Alzheimer's disease.
Journal: Proteomics 20050401
Title: The effect of lovastatin and thioridazine on the degradation of cocaine in human serum in vitro.
Journal: Therapeutic drug monitoring 20050401
Title: Heart failure and statins--why do we need a clinical trial?
Journal: Zeitschrift fur Kardiologie 20050401
Title: Disruption of lipid rafts causes apoptotic cell death in HaCaT keratinocytes.
Journal: Experimental dermatology 20050401
Title: [Effects of fosmidomycin and lovastatin treatment on taxol biosynthesis in suspension culture cells of Taxus chinensis].
Journal: Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20050401
Title: Lovastatin-induced apoptosis in human melanoma cell lines.
Journal: Melanoma research 20050401
Title: Targeted therapy in multiple myeloma.
Journal: Cancer control : journal of the Moffitt Cancer Center 20050401
Title: A role for hydroxy-methylglutaryl coenzyme a reductase in pulmonary inflammation and host defense.
Journal: American journal of respiratory and critical care medicine 20050315
Title: The regulation of beta-secretase by cholesterol and statins in Alzheimer's disease.
Journal: Journal of the neurological sciences 20050315
Title: Targeting the mevalonate pathway inhibits the function of the epidermal growth factor receptor.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050315
Title: Pellet morphology, culture rheology and lovastatin production in cultures of Aspergillus terreus.
Journal: Journal of biotechnology 20050302
Title: Progesterone-receptor antagonists and statins decrease de novo cholesterol synthesis and increase apoptosis in rat and human periovulatory granulosa cells in vitro.
Journal: Biology of reproduction 20050301
Title: A Phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix.
Journal: European journal of cancer (Oxford, England : 1990) 20050301
Title: FDA advisers vote against nonprescription lovastatin.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050301
Title: Is atorvastatin more appropriate to use in combination with niacin than simvastatin in patients with the metabolic syndrome?
Journal: American heart journal 20050301
Title: Lovastatin enhances in vitro radiation-induced apoptosis of rat B-cell lymphoma cells.
Journal: Journal of experimental & clinical cancer research : CR 20050301
Title: A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line.
Journal: The AAPS journal 20050301
Title: Ongoing clinical trials of the pleiotropic effects of statins.
Journal: Vascular health and risk management 20050301
Title: Clinical outcomes and management of mechanism-based inhibition of cytochrome P450 3A4.
Journal: Therapeutics and clinical risk management 20050301
Title: Suppression of autoimmune retinal disease by lovastatin does not require Th2 cytokine induction.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050215
Title: [The 'healthy' patient with hypercholesterolemia].
Journal: Medizinische Klinik (Munich, Germany : 1983) 20050215
Title: Statin-inhibited endothelial permeability could be associated with its effect on PECAM-1 in endothelial cells.
Journal: FEBS letters 20050214
Title: Chronic administration of statins alters multiple gene expression patterns in mouse cerebral cortex.
Journal: The Journal of pharmacology and experimental therapeutics 20050201
Title: Statins as coronary vasodilators in isolated bovine coronary arteries--involvement of PGI2 and NO.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20050201
Title: Differential effects of RhoA signaling on anticancer agent-induced cell death.
Journal: Oncology reports 20050201
Title: Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update.
Journal: Fundamental & clinical pharmacology 20050201
Title: Existence of a clinically relevant interaction between clopidogrel and HMG-CoA reductase inhibitors? Re-evaluating the evidence.
Journal: Basic & clinical pharmacology & toxicology 20050201
Title: Gender-specific effects of estrogen receptor alpha gene haplotype on high-density lipoprotein cholesterol response to atorvastatin: interaction with apolipoprotein AI gene polymorphism.
Journal: Atherosclerosis 20050201
Title: Lovastatin compromises C-reactive protein induced endothelial dysfunction including altered expression of cell adhesion molecules and increased monocyte recruitment.
Journal: Atherosclerosis 20050201
Title: Patients with elevated baseline liver enzymes do not have higher frequency of hepatotoxicity from lovastatin than those with normal baseline liver enzymes.
Journal: The American journal of the medical sciences 20050201
Title: Statins and osteoporosis: a clinical review.
Journal: Pharmacotherapy 20050201
Title: Simultaneous determination of farnesyl and geranylgeranyl pyrophosphate levels in cultured cells.
Journal: Analytical biochemistry 20050101
Title: Factors regulating macrophage endocytosis of nanoparticles: implications for targeted magnetic resonance plaque imaging.
Journal: Atherosclerosis 20050101
Title: Inhibitory effects of mevastatin and a geranylgeranyl transferase I inhibitor (GGTI-2166) on mononuclear osteoclast formation induced by receptor activator of NF kappa B ligand (RANKL) or tumor necrosis factor-alpha (TNF-alpha).
Journal: Biochemical pharmacology 20050101
Title: Examination of 209 drugs for inhibition of cytochrome P450 2C8.
Journal: Journal of clinical pharmacology 20050101
Title: Rosuvastatin reduces plasma lipids by inhibiting VLDL production and enhancing hepatobiliary lipid excretion in ApoE*3-leiden mice.
Journal: Journal of cardiovascular pharmacology 20050101
Title: Effect of tadalafil on cytochrome P450 3A4-mediated clearance: studies in vitro and in vivo.
Journal: Clinical pharmacology and therapeutics 20050101
Title: Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK.
Journal: PLoS medicine 20050101
Title: Endogenous cytokinin oscillations control cell cycle progression of tobacco BY-2 cells.
Journal: Plant biology (Stuttgart, Germany) 20050101
Title: Cardiovascular pharmacotherapy and herbal medicines: the risk of drug interaction.
Journal: International journal of cardiology 20050101
Title: Changes in lipids over twelve months after initiating protease inhibitor therapy among persons treated for HIV/AIDS.
Journal: Lipids in health and disease 20050101
Title: Acute administration of red yeast rice (Monascus purpureus) depletes tissue coenzyme Q(10) levels in ICR mice.
Journal: The British journal of nutrition 20050101
Title: Parallel capillary electrophoresis for the quantitative screening of fermentation broths containing natural products.
Journal: Metabolic engineering 20050101
Title: Do the pleiotropic effects of statins in the vasculature predict a role in inflammatory diseases?
Journal: Arthritis research & therapy 20050101
Title: Human macrophages limit oxidation products in low density lipoprotein.
Journal: Lipids in health and disease 20050101
Title: Cost effectiveness of treating low HDL-cholesterol in the primary prevention of coronary heart disease.
Journal: PharmacoEconomics 20050101
Title: [Effects of withdrawal of statins on nitric oxide production in vascular endothelial cells].
Journal: Zhonghua nei ke za zhi 20050101
Title: The effects of cholesterol lowering with simvastatin on cause-specific mortality and on cancer incidence in 20,536 high-risk people: a randomised placebo-controlled trial [ISRCTN48489393].
Journal: BMC medicine 20050101
Title: Renewed interest in lovastatin following launch of Lovachol.
Journal: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20050101
Title: Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK.
Journal: Molecular and cellular biochemistry 20050101
Title: The 'Statinth' wonder of the world: a panacea for all illnesses or a bubble about to burst.
Journal: Journal of negative results in biomedicine 20050101
Title: Effect of cholesterol lowering and cardiovascular risk factors on the progression of aortoiliac arteriosclerosis: a quantitative cineangiography study.
Journal: Angiology 20050101
Title: [Protective effects of Lovastatin on early diabetic renal tissue and the possible mechanism].
Journal: Wei sheng yan jiu = Journal of hygiene research 20050101
Title: Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions.
Journal: Clinical pharmacokinetics 20050101
Title: The utility of pathway selective estrogen receptor ligands that inhibit nuclear factor-kappa B transcriptional activity in models of rheumatoid arthritis.
Journal: Arthritis research & therapy 20050101
Title: Effect of rosuvastatin on outcomes in chronic haemodialysis patients - design and rationale of the AURORA study.
Journal: Current controlled trials in cardiovascular medicine 20050101
Title: Comparison of rosuvastatin and atorvastatin for lipid lowering in patients with type 2 diabetes mellitus: results from the URANUS study.
Journal: Cardiovascular diabetology 20050101
Title: [Prevalence of nonmevalonate and mevalonate pathways for isoprenoid biosynthesis among bacteria of different systematic groups].
Journal: Mikrobiologiia 20050101
Title: Statins research unfinished saga: desirability versus feasibility.
Journal: Cardiovascular diabetology 20050101
Title: An association study of 43 SNPs in 16 candidate genes with atorvastatin response.
Journal: The pharmacogenomics journal 20050101
Title: [Isoprenoid pigments in representatives of the family Microbacteriaceae].
Journal: Mikrobiologiia 20050101
Title: Relationship between lipophilicity of BCS class III and IV drugs and the functional activity of peroral absorption enhancers.
Journal: Farmaco (Societa chimica italiana : 1989) 20050101
Title: Enzymatic examination of potential interaction between statins or fibrates and consumed Tricholoma equestre.
Journal: Przeglad lekarski 20050101
Title: Absorption enhancement, mechanistic and toxicity studies of medium chain fatty acids, cyclodextrins and bile salts as peroral absorption enhancers.
Journal: Farmaco (Societa chimica italiana : 1989) 20050101
Title: Time as a variable with niacin extended-release/lovastatin vs. atorvastatin and simvastatin.
Journal: Preventive cardiology 20050101
Title: Considerations in the treatment of dyslipidemia associated with chronic kidney failure and renal transplantation.
Journal: Preventive cardiology 20050101
Title: Treatment of dyslipidemia with lovastatin and ezetimibe in an adolescent with cholesterol ester storage disease.
Journal: Lipids in health and disease 20050101
Title: [Impact of dietotherapy with enterosorbent of marine origin on the indices of mineral and lipid metabolism for patients suffering from kidney diseases].
Journal: Voprosy pitaniia 20050101
Title: Cost-effectiveness of rosuvastatin compared with other statins from a managed care perspective.
Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20050101
Title: Pharmacist intervention in safe and effective conversion of brand to generic drugs.
Journal: Journal of managed care pharmacy : JMCP 20050101
Title: Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation.
Journal: Journal of neuroinflammation 20050101
Title: [Interactions in solution between cyclodextrins and statins].
Journal: Acta pharmaceutica Hungarica 20050101
Title: Altered mitochondrial function and cholesterol synthesis influences protein synthesis in extended HepG2 spheroid cultures.
Journal: Archives of biochemistry and biophysics 20041215
Title: The antioxidant defense protein heme oxygenase 1 is a novel target for statins in endothelial cells.
Journal: Free radical biology & medicine 20041215
Title: Mechanistic and epidemiologic considerations in the evaluation of adverse birth outcomes following gestational exposure to statins.
Journal: American journal of medical genetics. Part A 20041215
Title: Statin-associated exacerbation of myasthenia gravis.
Journal: Neurology 20041214
Title: HMG-CoA reductase inhibitors induce COX-2 gene expression in murine macrophages: role of MAPK cascades and promoter elements for CREB and C/EBPbeta.
Journal: Experimental cell research 20041210
Title: Stanol esters decrease plasma cholesterol independently of intestinal ABC sterol transporters and Niemann-Pick C1-like 1 protein gene expression.
Journal: Journal of lipid research 20041201
Title: Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20041201
Title: Niacin therapy in atherosclerosis.
Journal: Current opinion in lipidology 20041201
Title: Lovastatin potentiates antitumor effects of saquinavir against human lymphoma cells.
Journal: Oncology reports 20041201
Title: Hypolipidemic drugs can change the composition of rat brain lipids.
Journal: The Tohoku journal of experimental medicine 20041201
Title: [Effects of lovastatin on renal function and expression of phosphorylating-p38 mitogen-activated protein kinase in experimental diabetic nephropathy in rats].
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20041201
Title: Atazanavir for the treatment of human immunodeficiency virus infection.
Journal: Pharmacotherapy 20041201
Title: Randomized trial of the effects of simvastatin on cognitive functioning in hypercholesterolemic adults.
Journal: The American journal of medicine 20041201
Title: Consistency in efficacy and safety of ezetimibe coadministered with statins for treatment of hypercholesterolemia in women and men.
Journal: Journal of women's health (2002) 20041201
Title: [Therapeutic compliance in the prevention of primary cardiovascular diseases with lovastatine. PRELOVAS study].
Journal: Medicina clinica 20041120
Title: Modified mutation method for screening low citrinin-producing strains of Monascus purpureus on rice culture.
Journal: Journal of agricultural and food chemistry 20041117
Title: Fluvastatin and lovastatin but not pravastatin induce neuroglial differentiation in human mesenchymal stem cells.
Journal: Journal of cellular biochemistry 20041115
Title: A Consumer Use Study of Over-The-Counter lovastatin (CUSTOM).
Journal: The American journal of cardiology 20041115
Title: Over-the-counter statin drug.
Journal: The American journal of cardiology 20041115
Title: Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors on microglia.
Journal: The Journal of biological chemistry 20041112
Title: Recurrent acute pancreatitis possibly induced by atorvastatin and rosuvastatin. Is statin induced pancreatitis a class effect?
Journal: JOP : Journal of the pancreas 20041110
Title: Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells.
Journal: Circulation 20041109
Title: Improved lymphocyte function-associated antigen-1 (LFA-1) inhibition by statin derivatives: molecular basis determined by x-ray analysis and monitoring of LFA-1 conformational changes in vitro and ex vivo.
Journal: The Journal of biological chemistry 20041105
Title: Consumer behavior in the setting of over-the-counter statin availability: lessons from the consumer use study of OTC Mevacor.
Journal: The American journal of cardiology 20041104
Title: Lovastatin exacerbates atypical absence seizures with only minimal effects on brain sterols.
Journal: Journal of lipid research 20041101
Title: Statin inhibition of Fc receptor-mediated phagocytosis by macrophages is modulated by cell activation and cholesterol.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20041101
Title: Bis[3-(4'-substituted phenyl)prop-2-ene]disulfides as a new class of antihyperlipidemic compounds.
Journal: Bioorganic & medicinal chemistry letters 20041101
Title: Statin compounds reduce human immunodeficiency virus type 1 replication by preventing the interaction between virion-associated host intercellular adhesion molecule 1 and its natural cell surface ligand LFA-1.
Journal: Journal of virology 20041101
Title: Synergistic upregulation of low-density lipoprotein receptor activity by tamoxifen and lovastatin.
Journal: Cardiovascular research 20041101
Title: OTC status for low-dose lovastatin would have widespread implications.
Journal: Managed care (Langhorne, Pa.) 20041101
Title: Lovastatin modulation of microglial activation via suppression of functional CD40 expression.
Journal: Journal of neuroscience research 20041015
Title: Lovastatin inhibits tumor growth and lung metastasis in mouse mammary carcinoma model: a p53-independent mitochondrial-mediated apoptotic mechanism.
Journal: Carcinogenesis 20041001
Title: Management of hypertriglyceridemia in patients receiving interferon for malignant melanoma.
Journal: The Annals of pharmacotherapy 20041001
Title: Impaired peroxisomal function in the central nervous system with inflammatory disease of experimental autoimmune encephalomyelitis animals and protection by lovastatin treatment.
Journal: Brain research 20041001
Title: Antihypercholesterolemic property of naringin alters plasma and tissue lipids, cholesterol-regulating enzymes, fecal sterol and tissue morphology in rabbits.
Journal: Clinical nutrition (Edinburgh, Scotland) 20041001
Title: C-reactive protein-induced expression of CD40-CD40L and the effect of lovastatin and fenofibrate on it in human vascular endothelial cells.
Journal: Biological & pharmaceutical bulletin 20041001
Title: Mevastatin inhibits ovarian theca-interstitial cell proliferation and steroidogenesis.
Journal: Fertility and sterility 20041001
Title: Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1.
Journal: PLoS medicine 20041001
Title: Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity. 1976.
Journal: Atherosclerosis. Supplements 20041001
Title: Therapeutic effects of ml-236B in primary hypercholesterolemia. 1980.
Journal: Atherosclerosis. Supplements 20041001
Title: Effects of an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase on serum lipoproteins and ubiquinone-10 levels in patients with familial hypercholesterolemia. 1981.
Journal: Atherosclerosis. Supplements 20041001
Title: Lowering plasma cholesterol by raising ldl receptors. 1981.
Journal: Atherosclerosis. Supplements 20041001
Title: Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholeserolemia heterozygotes. 1983.
Journal: Atherosclerosis. Supplements 20041001
Title: Effects of lovastatin and pravastatin on amyloid processing and inflammatory response in TgCRND8 brain.
Journal: Neurochemical research 20041001
Title: [Study on space flight-mutants of Monascus purpureus using Random Amplified Polymorphic DNA].
Journal: Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering 20041001
Title: Dietary palmitic acid influences LDL-mediated lymphocyte proliferation differently to other mono- and polyunsaturated fatty acids in rats.
Journal: Diabetes, nutrition & metabolism 20041001
Title: The HMG-CoA reductase inhibitor simvastatin overcomes cell adhesion-mediated drug resistance in multiple myeloma by geranylgeranylation of Rho protein and activation of Rho kinase.
Journal: Blood 20040915
Title: Cholesterol synthesis and import contribute to protective cholesterol increments in acute myeloid leukemia cells.
Journal: Blood 20040915
Title: Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosis.
Journal: Cancer research 20040915
Title: Development of methodologies based on HPLC and Raman spectroscopy for monitoring the stability of lovastatin in solid state in the presence of gallic acid.
Journal: Journal of pharmaceutical and biomedical analysis 20040903
Title: Identification and chemical profiling of monacolins in red yeast rice using high-performance liquid chromatography with photodiode array detector and mass spectrometry.
Journal: Journal of pharmaceutical and biomedical analysis 20040903
Title: Cholesterol depletion upregulates involucrin expression in epidermal keratinocytes through activation of p38.
Journal: The Journal of investigative dermatology 20040901
Title: Development of an acetylene black-dihexadecyl hydrogen phosphate composite-modified glassy-carbon electrode, and its application in the determination of lovastatin in dosage drug forms.
Journal: Analytical and bioanalytical chemistry 20040901
Title: Statins inhibit reoxygenation-induced cardiomyocyte apoptosis: role for glycogen synthase kinase 3beta and transcription factor beta-catenin.
Journal: Journal of molecular and cellular cardiology 20040901
Title: [Vastatins in atherosclerosis prevention. Current data].
Journal: Arquivos brasileiros de cardiologia 20040901
Title: Pharmacokinetic interaction between ezetimibe and lovastatin in healthy volunteers.
Journal: Current medical research and opinion 20040901
Title: Oral administration of pravastatin reduces egg cholesterol but not plasma cholesterol in laying hens.
Journal: Poultry science 20040901
Title: New decalin derivatives, eujavanoic acids A and B, from Eupenicillium javanicum.
Journal: Journal of natural products 20040901
Title: Rosuvastatin in the management of hyperlipidemia.
Journal: Clinical therapeutics 20040901
Title: Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways.
Journal: Circulation research 20040820
Title: Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins.
Journal: Circulation 20040817
Title: Statins inhibit HIV-1 infection by down-regulating Rho activity.
Journal: The Journal of experimental medicine 20040816
Title: Ionizing radiation-induced E-selectin gene expression and tumor cell adhesion is inhibited by lovastatin and all-trans retinoic acid.
Journal: Carcinogenesis 20040801
Title: Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin.
Journal: Blood 20040801
Title: Acute activation and phosphorylation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors.
Journal: American journal of physiology. Heart and circulatory physiology 20040801
Title: Chronic mevastatin modulates receptor-dependent vascular contraction in eNOS-deficient mice.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20040801
Title: Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20040801
Title: Cholesterol (and cardiovascular risk) in adolescence.
Journal: Current opinion in pediatrics 20040801
Title: Safety and compliance with once-daily niacin extended-release/lovastatin as initial therapy in the Impact of Medical Subspecialty on Patient Compliance to Treatment (IMPACT) study.
Journal: The American journal of cardiology 20040801
Title: Lipid-lowering response to statins is affected by CYP3A5 polymorphism.
Journal: Pharmacogenetics 20040801
Title: Focal adhesion kinase mediates endothelin-induced cyclin D3 expression in rat cultured astrocytes.
Journal: Journal of neurochemistry 20040801
Title: [Effects of lovastatin on cell cycle distribution in MCF-7 cells transfected with BRCA1].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20040801
Title: The hypolipidemic compound cetaben induces changes in Golgi morphology and vesicle movement.
Journal: Histochemistry and cell biology 20040801
Title: The multifunctional role of fibroblasts during wound healing in Hirudo medicinalis (Annelida, Hirudinea).
Journal: Biology of the cell 20040801
Title: Efficacy and safety of ezetimibe coadministered with statins: randomised, placebo-controlled, blinded experience in 2382 patients with primary hypercholesterolemia.
Journal: International journal of clinical practice 20040801
Title: Lipid rafts mediate the synaptic localization of alpha-synuclein.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040728
Title: Depletion of membrane cholesterol causes ligand-independent activation of Fas and apoptosis.
Journal: Biochemical and biophysical research communications 20040716
Title: Evaluation of hesperetin 7-O-lauryl ether as lipid-lowering agent in high-cholesterol-fed rats.
Journal: Bioorganic & medicinal chemistry 20040701
Title: Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin.
Journal: Journal of neuroscience research 20040701
Title: Differential effects of simvastatin on mesangial cells.
Journal: Kidney international 20040701
Title: Genetically modified mice and their use in developing therapeutic strategies for prostate cancer.
Journal: The Journal of urology 20040701
Title: Extended-release niacin/lovastatin: the first combination product for dyslipidemia.
Journal: Expert review of cardiovascular therapy 20040701
Title: Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention.
Journal: Experimental biology and medicine (Maywood, N.J.) 20040701
Title: Apoptotic injury in cultured human hepatocytes induced by HMG-CoA reductase inhibitors.
Journal: Biochemical pharmacology 20040615
Title: Compactin-a review.
Journal: Applied microbiology and biotechnology 20040601
Title: Maintenance of G1 checkpoint controls in telomerase-immortalized endothelial cells.
Journal: Cell cycle (Georgetown, Tex.) 20040601
Title: Cell-based screen of HMG-CoA reductase inhibitors and expression regulators using LC-MS.
Journal: Analytical biochemistry 20040601
Title: Inhibition of the class II HMG-CoA reductase of Pseudomonas mevalonii.
Journal: Protein science : a publication of the Protein Society 20040601
Title: Extended-release niacin for modifying the lipoprotein profile.
Journal: Expert opinion on pharmacotherapy 20040601
Title: Multisite inhibition by phenylacetate of PC-3 cell growth.
Journal: Anti-cancer drugs 20040601
Title: Overdependence on the host-an Achilles' heel of HCV?
Journal: Hepatology (Baltimore, Md.) 20040601
Title: Statins: novel additions to the dermatologic arsenal?
Journal: Experimental dermatology 20040601
Title: Effects of ezetimibe on the pharmacodynamics and pharmacokinetics of lovastatin.
Journal: Current medical research and opinion 20040601
Title: [In vitro effects of mevastatin on the proliferation and apoptosis in human multiple myeloma cell line U266].
Journal: Zhongguo shi yan xue ye xue za zhi 20040601
Title: Metaanalysis of statins and survival in de novo cardiac transplantation.
Journal: Transplantation proceedings 20040601
Title: The role of maternal toxicity in lovastatin-induced developmental toxicity.
Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20040601
Title: Molecular basis of ML-236B production in the high-producing mutant No. 41520 of Penicillium citrinum.
Journal: The Journal of general and applied microbiology 20040601
Title: Efficacy of extended-release niacin with lovastatin for hypercholesterolemia: assessing all reasonable doses with innovative surface graph analysis.
Journal: Archives of internal medicine 20040524
Title: Statin-derived 1,3-oxazinan-2-ones as submicromolar inhibitors of LFA-1/ICAM-1 interaction: stabilization of the metabolically labile vanillyl side chain.
Journal: Bioorganic & medicinal chemistry letters 20040517
Title: Hydrophilic 7 beta-hydroxy bile acids, lovastatin, and cholestyramine are ineffective in the treatment of cerebrotendinous xanthomatosis.
Journal: Metabolism: clinical and experimental 20040501
Title: Class-specific pro-apoptotic effect of statins on human vascular endothelial cells.
Journal: Zeitschrift fur Kardiologie 20040501
Title: Effect of administration of lovastatin on the development of late pulmonary effects after whole-lung irradiation in a murine model.
Journal: Radiation research 20040501
Title: Statins and liver toxicity: a meta-analysis.
Journal: Pharmacotherapy 20040501
Title: Betulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells in mice.
Journal: British journal of cancer 20040419
Title: Statins downregulate ATP-binding-cassette transporter A1 gene expression in macrophages.
Journal: Biochemical and biophysical research communications 20040409
Title: Cyclin E deregulation alters the biologic properties of ovarian cancer cells.
Journal: Oncogene 20040408
Title: Professional athletes suffering from familial hypercholesterolaemia rarely tolerate statin treatment because of muscular problems.
Journal: British journal of clinical pharmacology 20040401
Title: Psychological and cognitive function: predictors of adherence with cholesterol lowering treatment.
Journal: Annals of behavioral medicine : a publication of the Society of Behavioral Medicine 20040401
Title: Lovastatin-induced up-regulation of the BH3-only protein, Bim, and cell death in glioblastoma cells.
Journal: Journal of neurochemistry 20040401
Title: Depletion of cellular cholesterol and lipid rafts increases shedding of CD30.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040401
Title: LaeA, a regulator of secondary metabolism in Aspergillus spp.
Journal: Eukaryotic cell 20040401
Title: Inhibition of Rho modulates cytokine-induced prostaglandin E2 formation in renal mesangial cells.
Journal: Biochimica et biophysica acta 20040322
Title: Statins inhibit osteoblast migration by inhibiting Rac-Akt signaling.
Journal: Biochemical and biophysical research communications 20040312
Title: Rational elimination of Aspergillus terreus sulochrin production.
Journal: Journal of biotechnology 20040304
Title: Effects of brassinazole, an inhibitor of brassinosteroid biosynthesis, on light- and dark-grown Chlorella vulgaris.
Journal: Planta 20040301
Title: Blood-brain barrier permeability and monocyte infiltration in experimental allergic encephalomyelitis: a quantitative MRI study.
Journal: Brain : a journal of neurology 20040301
Title: Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20040301
Title: Loss of function of 3-hydroxy-3-methylglutaryl coenzyme A reductase 1 (HMG1) in Arabidopsis leads to dwarfing, early senescence and male sterility, and reduced sterol levels.
Journal: The Plant journal : for cell and molecular biology 20040301
Title: De novo biosynthesis and radiolabeling of mammalian digitalis-like factors.
Journal: Clinical chemistry 20040301
Title: Eggplant (Solanum melongena) extract does not alter serum lipid levels.
Journal: Arquivos brasileiros de cardiologia 20040301
Title: Association of dyslipidemia and effects of statins on nonmacrovascular diseases.
Journal: Clinical therapeutics 20040301
Title: Naringin alters the cholesterol biosynthesis and antioxidant enzyme activities in LDL receptor-knockout mice under cholesterol fed condition.
Journal: Life sciences 20040213
Title: Statin use and cancer risk in the General Practice Research Database.
Journal: British journal of cancer 20040209
Title: Role of cholesterol in the regulation of growth plate chondrogenesis and longitudinal bone growth.
Journal: The Journal of biological chemistry 20040206
Title: Hormonal changes with cholesterol reduction: a double-blind pilot study.
Journal: Journal of clinical pharmacy and therapeutics 20040201
Title: Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040201
Title: Oral anticoagulant drug interactions with statins: case report of fluvastatin and review of the literature.
Journal: Pharmacotherapy 20040201
Title: Atorvastatin: gold standard for prophylaxis of myocardial ischemia and stroke - comparison of the clinical benefit of statins on the basis of randomized controlled endpoint studies.
Journal: European journal of medical research 20040126
Title: Leukaemia inhibitory factor or oncostatin M induction of Swiss 3T3 cells does not require mevalonic acid synthesis nor protein isoprenylation to initiate DNA replication.
Journal: Biochemical and biophysical research communications 20040123
Title: Statins potentiate caspase-3 activity in immortalized murine neurons.
Journal: Neuroscience letters 20040123
Title: Influence of lipid lowering fibrates on P-glycoprotein activity in vitro.
Journal: Biochemical pharmacology 20040115
Title: Statins upregulate CD36 expression in human monocytes, an effect strengthened when combined with PPAR-gamma ligands Putative contribution of Rho GTPases in statin-induced CD36 expression.
Journal: Biochemical pharmacology 20040115
Title: Potential targets of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor for multiple sclerosis therapy.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040115
Title: Lovastatin and mevastatin reduce basal and cytokine-stimulated production of prostaglandins from rat microglial cells in vitro: evidence for a mechanism unrelated to the inhibition of hydroxy-methyl-glutaryl CoA reductase.
Journal: Neuroscience letters 20040109
Title: Lovastatin inhibits Rho-regulated expression of E-selectin by TNFalpha and attenuates tumor cell adhesion.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040101
Title: Biosynthesis of camptothecin. In silico and in vivo tracer study from [1-13C]glucose.
Journal: Plant physiology 20040101
Title: Distinct light-mediated pathways regulate the biosynthesis and exchange of isoprenoid precursors during Arabidopsis seedling development.
Journal: The Plant cell 20040101
Title: Differential effects of lipid-lowering agents on human cholinesterases.
Journal: Clinical biochemistry 20040101
Title: Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancer.
Journal: Breast cancer research : BCR 20040101
Title: Statin therapy in patients with coronary artery disease improves the impaired endothelial progenitor cell differentiation into cardiomyogenic cells.
Journal: Basic research in cardiology 20040101
Title: Comparisons of effects of statins (atorvastatin, fluvastatin, lovastatin, pravastatin, and simvastatin) on fasting and postprandial lipoproteins in patients with coronary heart disease versus control subjects.
Journal: The American journal of cardiology 20040101
Title: Allocation of resources between smoking cessation methods and lovastatin treatment of hypercholesterolaemia: based on cost effectiveness and the social welfare function.
Journal: PharmacoEconomics 20040101
Title: Lovastatin inhibits its own synthesis in Aspergillus terreus.
Journal: Journal of industrial microbiology & biotechnology 20040101
Title: Efficacy of once-daily extended-release lovastatin as compared to immediate-release lovastatin in patients with hypercholesterolemia.
Journal: Current medical research and opinion 20040101
Title: Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs.
Journal: Lipids in health and disease 20040101
Title: [X-linked adrenoleukodystrophy (ALD)].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20040101
Title: Gene transfer into human hepatoma cells by receptor-associated protein/polylysine conjugates.
Journal: Bioconjugate chemistry 20040101
Title: Down-regulating effect of nicotine on connexin43 gap junctions in human umbilical vein endothelial cells is attenuated by statins.
Journal: European journal of cell biology 20040101
Title: Rising statin use and effect on ischemic stroke outcome.
Journal: BMC medicine 20040101
Title: C-reactive protein is not only an inflammatory marker but also a direct cause of cardiovascular diseases.
Journal: Medical hypotheses 20040101
Title: Expression and localization of nuclear proteins in autosomal-dominant Emery-Dreifuss muscular dystrophy with LMNA R377H mutation.
Journal: BMC cell biology 20040101
Title: Effect of Lovastatin on lipid peroxidation and total antioxidant concentrations in hemodialysis patients.
Journal: Lipids in health and disease 20040101
Title: The influence of statins on the free intracellular calcium concentration in human umbilical vein endothelial cells.
Journal: BMC cardiovascular disorders 20040101
Title: Assessing compliance of cardiologists with the national cholesterol education program (NCEP) III guidelines in an ambulatory care setting.
Journal: Lipids in health and disease 20040101
Title: Lichenoid drug eruption with HMG-CoA reductase inhibitors (fluvastatin and lovastatin).
Journal: Acta dermato-venereologica 20040101
Title: DRF 3188 a novel semi-synthetic analog of andrographolide: cellular response to MCF 7 breast cancer cells.
Journal: BMC cancer 20040101
Title: Statins rise cytoplasmic calcium level [Ca2+]i in cultured endothelial cells.
Journal: Polish journal of pharmacology 20040101
Title: [Idiopathic membranous nephropathy associated with anti-calcineurin toxicity. Prognosis and other immunosuppressive treatments].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101
Title: Effect of Nandrolone Decanoate on serum lipoprotein (a) and its isoforms in hemodialysis patients.
Journal: Lipids in health and disease 20040101
Title: Cost-effectiveness analysis of simvastatin and lovastatin/extended- release niacin to achieve LDL and HDL goal using NHANES data.
Journal: Journal of managed care pharmacy : JMCP 20040101
Title: Combinatorial chemoprevention: efficacy of lovostatin and exisulind on the formation and progression of aberrant crypt foci.
Journal: Anticancer research 20040101
Title: Mevastatin-induced apoptosis and growth suppression in U266 myeloma cells.
Journal: Anticancer research 20040101
Title: Role of isoprenoids in cytoskeleton integrity and albumin endocytosis by opossum kidney cells.
Journal: Nephron. Experimental nephrology 20040101
Title: Pharmacokinetic study on lovastatin sustained-release tablet and sustained-release capsule in Beagal dogs.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20040101
Title: Low-molecular-weight cyclin E: the missing link between biology and clinical outcome.
Journal: Breast cancer research : BCR 20040101
Title: Metabolic cholesterol depletion hinders cell-surface trafficking of the nicotinic acetylcholine receptor.
Journal: Neuroscience 20040101
Title: Interactions between grapefruit juice and cardiovascular drugs.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101
Title: Effect of time of administration on cholesterol-lowering by psyllium: a randomized cross-over study in normocholesterolemic or slightly hypercholesterolemic subjects.
Journal: Nutrition journal 20040101
Title: [Lovastatin effect on ergosterol production and growth of Tolypocladium inflatum 106].
Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101
Title: The pivotal role of cholesterol absorption inhibitors in the management of dyslipidemia.
Journal: Lipids in health and disease 20040101
Title: Influence of lovastatin on BCL-2 and BAX expression by plasma cells and T lymphocytes in short-term cultures of multiple myeloma bone marrow mononuclear cells.
Journal: Polish journal of pharmacology 20040101
Title: Sparse graphical Gaussian modeling of the isoprenoid gene network in Arabidopsis thaliana.
Journal: Genome biology 20040101
Title: The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases.
Journal: Genome biology 20040101
Title: Lipoprotein lipase locus and progression of atherosclerosis in coronary-artery bypass grafts.
Journal: Genetics in medicine : official journal of the American College of Medical Genetics 20040101
Title: Effect of 3,4-di(OH)-cinnamate synthetic derivative on plasma and hepatic cholesterol level and antioxidant enzyme activities in high cholesterol-fed rats.
Journal: Journal of biochemical and molecular toxicology 20040101
Title: Cytoskeletal actin degradation induced by lovastatin in cardiomyocytes is mediated through caspase-2.
Journal: Cell biology international 20040101
Title: The need for a large-scale trial of fibrate therapy in diabetes: the rationale and design of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. [ISRCTN64783481].
Journal: Cardiovascular diabetology 20040101
Title: [Thrombocytic hemostasis in hypertensive patients with metabolic syndrome and its correction with lovastatin].
Journal: Klinicheskaia meditsina 20040101
Title: Anti-Plasmodium activity of ceramide analogs.
Journal: Malaria journal 20040101
Title: Lipid metabolism in zebrafish.
Journal: Methods in cell biology 20040101
Title: [Mevastatin induced apoptosis in U266 human myeloma cell line].
Journal: Magyar onkologia 20040101
Title: KGF-induced motility of breast cancer cells is dependent on Grb2 and Erk1,2.
Journal: Clinical & experimental metastasis 20040101
Title: [Screening of natural compounds with hypolipidemic activity].
Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101
Title: [Estimation of the efficacy of screened natural hypolipidemic compounds in a model of rabbit hypercholesterolemia].
Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101
Title: Farnesyl-O-acetylhydroquinone and geranyl-O-acetylhydroquinone suppress the proliferation of murine B16 melanoma cells, human prostate and colon adenocarcinoma cells, human lung carcinoma cells, and human leukemia cells.
Journal: Cancer letters 20031230
Title: Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20031223
Title: Lovastatin-induced cardiac toxicity involves both oncotic and apoptotic cell death with the apoptotic component blunted by both caspase-2 and caspase-3 inhibitors.
Journal: Toxicology and applied pharmacology 20031215
Title: Statins induce suppressor of cytokine signaling-3 in macrophages.
Journal: FEBS letters 20031204
Title: Two derivative spectrophotometric methods for the simultaneous determination of lovastatin combined with three antioxidants.
Journal: Journal of pharmaceutical and biomedical analysis 20031204
Title: Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20031201
Title: Proximal tubular cholesterol loading after mitochondrial, but not glycolytic, blockade.
Journal: American journal of physiology. Renal physiology 20031201
Title: Methyl palmitate: a novel product of the Medfly (Ceratitis capitata) corpus allatum.
Journal: Insect biochemistry and molecular biology 20031201
Title: Chinese red rice-induced myopathy.
Journal: Southern medical journal 20031201
Title: [Ezetimibe: from pharmacology to clinical trials].
Journal: Annales d'endocrinologie 20031201
Title: Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia.
Journal: British journal of cancer 20031117
Title: Protein geranylgeranylation is critical for the regulation of survival and proliferation of lymphoma tumor cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20031115
Title: Inhibition of hydroxymethylglutaryl-coenzyme a reductase reduces Th1 development and promotes Th2 development.
Journal: Circulation research 20031114
Title: Rosuvastatin in the primary prevention of cardiovascular disease among patients with low levels of low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: rationale and design of the JUPITER trial.
Journal: Circulation 20031111
Title: Effects of statins on platelet inhibition by a high loading dose of clopidogrel.
Journal: Circulation 20031104
Title: Inhibition of protein geranylgeranylation induces apoptosis in myeloma plasma cells by reducing Mcl-1 protein levels.
Journal: Blood 20031101
Title: Epidermal growth factor receptor-targeted therapy potentiates lovastatin-induced apoptosis in head and neck squamous cell carcinoma cells.
Journal: Journal of cancer research and clinical oncology 20031101
Title: 3-hydroxy-3-methylglutaryl-coenzyme A reductase in the lobster mandibular organ: regulation by the eyestalk.
Journal: General and comparative endocrinology 20031101
Title: Effects of cholesterol-lowering foods versus lovastatin on serum lipids and C-reactive protein.
Journal: Current atherosclerosis reports 20031101
Title: HMG-CoA reductase inhibition reduces the proinflammatory activation of human vascular smooth muscle cells by the terminal complement factor C5b-9.
Journal: Basic research in cardiology 20031101
Title: FK506 potentiates NGF-induced neurite outgrowth via the Ras/Raf/MAP kinase pathway.
Journal: British journal of pharmacology 20031101
Title: Rho A negatively regulates cytokine-mediated inducible nitric oxide synthase expression in brain-derived transformed cell lines: negative regulation of IKKalpha.
Journal: Free radical biology & medicine 20031101
Title: Effect of HMG-CoA reductase inhibitors on reduction of panel reactivity.
Journal: Transplantation proceedings 20031101
Title: Improvement of monacolin K, gamma-aminobutyric acid and citrinin production ratio as a function of environmental conditions of Monascus purpureus NTU 601.
Journal: Journal of industrial microbiology & biotechnology 20031101
Title: Cell-cycle gene expression in lovastatin-induced medulloblastoma apoptosis.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20031101
Title: Bioconversion of compactin into pravastatin by Streptomyces sp.
Journal: Biotechnology letters 20031101
Title: A multicenter, randomized, double-blind clinical trial comparing the low-density lipoprotein cholesterol-lowering ability of lovastatin 10, 20, and 40 mg/d with fluvastatin 20 and 40 mg/d.
Journal: Clinical therapeutics 20031101
Title: p21-dependent inhibition of colon cancer cell growth by mevastatin is independent of inhibition of G1 cyclin-dependent kinases.
Journal: The Journal of biological chemistry 20031031
Title: Unique induction of p21(WAF1/CIP1)expression by vinorelbine in androgen-independent prostate cancer cells.
Journal: British journal of cancer 20031020
Title: Inhibition of lysophosphatidic acid-induced RhoA activation and tumor cell invasion by 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors.
Journal: International journal of oncology 20031001
Title: Lipophilic statins interfere with the inhibitory effects of clopidogrel on platelet function--a flow cytometry study.
Journal: European heart journal 20031001
Title: Protective effects of lovastatin on vascular endothelium injured by low density lipoprotein.
Journal: Acta pharmacologica Sinica 20031001
Title: The bisphosphonate pamidronate is a potent inhibitor of Ewing's sarcoma cell growth in vitro.
Journal: Anti-cancer drugs 20031001
Title: Lovastatin inhibits adipogenic and stimulates osteogenic differentiation by suppressing PPARgamma2 and increasing Cbfa1/Runx2 expression in bone marrow mesenchymal cell cultures.
Journal: Bone 20031001
Title: Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase lower fecundity in the German cockroach: correlation between the effects on fecundity in vivo with the inhibition of enzymatic activity in embryo cells.
Journal: Pest management science 20031001
Title: The mevalonate synthesis pathway as a therapeutic target in cancer.
Journal: Clinical orthopaedics and related research 20031001
Title: Statins differentially regulate vascular endothelial growth factor synthesis in endothelial and vascular smooth muscle cells.
Journal: Atherosclerosis 20031001
Title: All hydrophobic HMG-CoA reductase inhibitors induce apoptotic death in rat pulmonary vein endothelial cells.
Journal: Atherosclerosis 20031001
Title: Antifungal activity of fluconazole in combination with lovastatin and their effects on gene expression in the ergosterol and prenylation pathways in Candida albicans.
Journal: Medical mycology 20031001
Title: [Effect of space flight on yield of Monascus purpureus].
Journal: Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering 20031001
Title: Cholesterol oxidase and the hydroxymethylglutaryl coenzyme A reductase inhibitor mevinolin perturb endocytic trafficking in cultured vascular smooth muscle cells.
Journal: Journal of submicroscopic cytology and pathology 20031001
Title: Small-molecule cyclin-dependent kinase modulators.
Journal: Oncogene 20030929
Title: cDNA cloning and gene expression analysis of human myo-inositol 1-phosphate synthase.
Journal: Archives of biochemistry and biophysics 20030915
Title: Lactonase and lactonizing activities of human serum paraoxonase (PON1) and rabbit serum PON3.
Journal: Biochemical pharmacology 20030915
Title: Cholesterol requirement of hepatitis B surface antigen (HBsAg) secretion.
Journal: Virology 20030915
Title: Thyroid hormone regulation and cholesterol metabolism are connected through Sterol Regulatory Element-Binding Protein-2 (SREBP-2).
Journal: The Journal of biological chemistry 20030905
Title: Lovastatin enhances Abeta production and senile plaque deposition in female Tg2576 mice.
Journal: Neurobiology of aging 20030901
Title: Inhibition of Rho family GTPases results in increased TNF-alpha production after lipopolysaccharide exposure.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030901
Title: Lovastatin induces apoptosis of anaplastic thyroid cancer cells via inhibition of protein geranylgeranylation and de novo protein synthesis.
Journal: Endocrinology 20030901
Title: Role of cholesterol-enriched diet and the mevalonate pathway in cardiac nitric oxide synthesis.
Journal: Basic research in cardiology 20030901
Title: Lovastatin induces relaxation and inhibits L-type Ca(2+) current in the rat basilar artery.
Journal: Pharmacology & toxicology 20030901
Title: Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells.
Journal: Cardiovascular research 20030901
Title: Statins differ in their ability to block NF-kappaB activation in human blood monocytes.
Journal: International journal of clinical pharmacology and therapeutics 20030901
Title: What's new in lipid management?
Journal: Pharmacotherapy 20030901
Title: Inhibition of lovastatin on proliferation and expression of proinflammatory cytokines in cultured human glomerular mesangial cells.
Journal: Chinese medical journal 20030901
Title: Cholesterol and tau protein--findings in Alzheimer's and Niemann Pick C's disease.
Journal: Pharmacopsychiatry 20030901
Title: Increased expression of plasminogen activator inhibitor-1 by mediators of the acute phase response: a potential progenitor of vasculopathy in hypertensives.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20030901
Title: Chronic pancreatitis.
Journal: Current opinion in gastroenterology 20030901
Title: Transport mechanism for lovastatin acid in bovine kidney NBL-1 cells: kinetic evidences imply involvement of monocarboxylate transporter 4.
Journal: International journal of pharmaceutics 20030827
Title: Lack of adverse clopidogrel-atorvastatin clinical interaction from secondary analysis of a randomized, placebo-controlled clopidogrel trial.
Journal: Circulation 20030826
Title: Analytical methods for the quantitative determination of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in biological samples.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030815
Title: Cholesterol deficiency increases the vulnerability of hippocampal glia in primary culture to glutamate-induced excitotoxicity.
Journal: Neurochemistry international 20030801
Title: [Cholesterol-reducing medications-a new therapeutic option for multiple sclerosis? Statins as immunomodulators].
Journal: Der Nervenarzt 20030801
Title: [Statin-induced Parkinson's-syndrome. Reader's letter on the article by J. Finsterer in 'Der Nervenarzt' (2003) 74:115-122].
Journal: Der Nervenarzt 20030801
Title: Treatment with lovastatin, cholestyramine or niacin alters K-ras membrane association in mouse lung in a strain-dependent manner: results in females.
Journal: Biochemical pharmacology 20030801
Title: Simvastatin.
Journal: Acta crystallographica. Section C, Crystal structure communications 20030801
Title: HMG-CoA reductase inhibitors induce apoptosis in neointima-derived vascular smooth muscle cells.
Journal: Atherosclerosis 20030801
Title: Mevastatin suppresses lipopolysaccharide-induced Rac activation in the human monocyte cell line THP-1.
Journal: Surgery 20030801
Title: Lovastatin causes sensitization of HeLa cells to ionizing radiation-induced apoptosis by the abrogation of G2 blockage.
Journal: International journal of radiation biology 20030801
Title: Effect of red mold rice supplements on serum and egg yolk cholesterol levels of laying hens.
Journal: Journal of agricultural and food chemistry 20030730
Title: Identifying the factors and signal pathways necessary for anchorage-independent growth of Ha-ras oncogene-transformed NIH/3T3 cells.
Journal: Life sciences 20030725
Title: Ultraviolet light-induced apoptotic death is impaired by the HMG-CoA reductase inhibitor lovastatin.
Journal: Biochemical and biophysical research communications 20030725
Title: Effects of a dietary portfolio of cholesterol-lowering foods vs lovastatin on serum lipids and C-reactive protein.
Journal: JAMA 20030723
Title: Cross-talk between the cytosolic mevalonate and the plastidial methylerythritol phosphate pathways in tobacco bright yellow-2 cells.
Journal: The Journal of biological chemistry 20030718
Title: Growth factor induced activation of Rho and Rac GTPases and actin cytoskeletal reorganization in human lens epithelial cells.
Journal: Molecular vision 20030717
Title: Osteoblast-derived oxysterol is a migration-inducing factor for human breast cancer cells.
Journal: The Journal of biological chemistry 20030711
Title: Monacolin N, a compound resulting from derailment of type I iterative polyketide synthase function en route to lovastatin.
Journal: Chemical communications (Cambridge, England) 20030707
Title: Synergistic growth inhibitory effects of interferon-alpha and lovastatin on bcr-abl positive leukemic cells.
Journal: International journal of oncology 20030701
Title: Mechanism of simvastatin on induction of heat shock protein in osteoblasts.
Journal: Archives of biochemistry and biophysics 20030701
Title: Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors.
Journal: Nature reviews. Drug discovery 20030701
Title: Statins sentence thyroid cancer cells to death rho.
Journal: The Journal of clinical endocrinology and metabolism 20030701
Title: Lovastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, induces apoptosis and differentiation in human anaplastic thyroid carcinoma cells.
Journal: The Journal of clinical endocrinology and metabolism 20030701
Title: Therapeutic implications of recent ATP III guidelines and the important role of combination therapy in total dyslipidemia management.
Journal: Current opinion in cardiology 20030701
Title: Statin-associated memory loss: analysis of 60 case reports and review of the literature.
Journal: Pharmacotherapy 20030701
Title: [Effect of lovastatin on the expression of IkappaBalpha and cell-cycle regulating protein in MCF-7 cells].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20030701
Title: Increase in cholesterol and cholesterol oxidation products, and role of cholesterol oxidation products in kainate-induced neuronal injury.
Journal: Brain pathology (Zurich, Switzerland) 20030701
Title: Isoprenoid alcohols restore protein isoprenylation in a time-dependent manner independent of protein synthesis.
Journal: Lipids 20030701
Title: [Efficacy and safety of combined statin-fenofibrates therapy compared with monotherapy in patients with mixed hyperlipidemia and high risk of coronary heart disease].
Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030701
Title: Biochemical studies on marine fish oil part-I: effects of fish oil and lipid lowering drugs on HDL/LDL cholesterol levels.
Journal: Pakistan journal of pharmaceutical sciences 20030701
Title: Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis.
Journal: BMJ (Clinical research ed.) 20030628
Title: Correlation of statin-increased platelet APP ratios and reduced blood lipids in AD patients.
Journal: Neurology 20030624
Title: Of cancer and cholesterol: studies elucidate anticancer mechanisms of statins.
Journal: Journal of the National Cancer Institute 20030618
Title: Monoterpene regulation of Ras and Ras-related protein expression.
Journal: Journal of lipid research 20030601
Title: Effect of fruits of Moringa oleifera on the lipid profile of normal and hypercholesterolaemic rabbits.
Journal: Journal of ethnopharmacology 20030601
Title: Cost effectiveness of statin therapy for the primary prevention of major coronary events in individuals with type 2 diabetes.
Journal: Diabetes care 20030601
Title: Biosynthetic maturation of the corpus allatum of the female adult medfly, Ceratitis capitata, and its putative control.
Journal: Journal of insect physiology 20030601
Title: Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance.
Journal: Clinical pharmacology and therapeutics 20030601
Title: Collision-induced dissociation of the negative ions of simvastatin hydroxy acid and related species.
Journal: Journal of mass spectrometry : JMS 20030601
Title: Therapeutic potential of lovastatin in multiple sclerosis.
Journal: Journal of neurology 20030601
Title: Hypolipidemic and anti-atherogenic effects of long-term Cholestin (Monascus purpureus-fermented rice, red yeast rice) in cholesterol fed rabbits.
Journal: The Journal of nutritional biochemistry 20030601
Title: Current perspectives on statins.
Journal: Journal of the Indian Medical Association 20030601
Title: Crystal structure of a statin bound to a class II hydroxymethylglutaryl-CoA reductase.
Journal: The Journal of biological chemistry 20030530
Title: Activation of insulin-like growth factor II signaling by mutant type p53: physiological implications for potentiation of IGF-II signaling by p53 mutant 249.
Journal: Molecular and cellular endocrinology 20030530
Title: Determination of cholesterol-lowering statin drugs in aqueous samples using liquid chromatography-electrospray ionization tandem mass spectrometry.
Journal: Journal of chromatography. A 20030523
Title: Molecular cloning and characterization of CLICK-III/CaMKIgamma, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK).
Journal: The Journal of biological chemistry 20030516
Title: HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes.
Journal: Circulation research 20030516
Title: Cholesterol-modulating agents kill acute myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cholesterol responses.
Journal: Blood 20030501
Title: Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030501
Title: Statins inhibit secretion of metalloproteinases-1, -2, -3, and -9 from vascular smooth muscle cells and macrophages.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20030501
Title: Effect of HMG-CoA reductase inhibitors on proliferation and protein synthesis by rat hepatic stellate cells.
Journal: Journal of hepatology 20030501
Title: Treating dyslipidemic patients with lipid-modifying and combination therapies.
Journal: Pharmacotherapy 20030501
Title: Acute pancreatitis due to pravastatin therapy.
Journal: JOP : Journal of the pancreas 20030501
Title: Three new drugs for hyperlipidemia.
Journal: Connecticut medicine 20030501
Title: Lovastatin and phospholipase Cgamma regulate constitutive and protein kinase C dependent integrin mediated interactions of human T-cells with collagen.
Journal: Cellular immunology 20030501
Title: Lovastatin inhibits bone marrow-derived dendritic cell maturation and upregulates proinflammatory cytokine production.
Journal: Cellular immunology 20030501
Title: Ezetimibe: a novel option for lowering cholesterol.
Journal: Expert review of cardiovascular therapy 20030501
Title: Inhibition of pancreatic stellate cell activation by the hydroxymethylglutaryl coenzyme A reductase inhibitor lovastatin.
Journal: Biochemical pharmacology 20030415
Title: Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415
Title: High-density lipoprotein subpopulations in pathologic conditions.
Journal: The American journal of cardiology 20030403
Title: Role of c-Src in regulation of endothelial nitric oxide synthase expression during exercise training.
Journal: American journal of physiology. Heart and circulatory physiology 20030401
Title: A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.
Journal: Nature genetics 20030401
Title: Residual effects of lovastatin and simvastatin on urinary mevalonate excretions in patients with familial hypercholesterolemia.
Journal: The Journal of laboratory and clinical medicine 20030401
Title: Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease.
Journal: Archives of neurology 20030401
Title: Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction.
Journal: Molecular and cellular biochemistry 20030401
Title: Safety and statin therapy: reconsidering the risks and benefits.
Journal: Archives of internal medicine 20030324
Title: Differential effects of lipid-lowering therapies on stroke prevention: a meta-analysis of randomized trials.
Journal: Archives of internal medicine 20030324
Title: Mevastatin can cause G1 arrest and induce apoptosis in pulmonary artery smooth muscle cells through a p27Kip1-independent pathway.
Journal: Circulation research 20030321
Title: Comparison of once-daily, niacin extended-release/lovastatin with standard doses of atorvastatin and simvastatin (the ADvicor Versus Other Cholesterol-Modulating Agents Trial Evaluation [ADVOCATE]).
Journal: The American journal of cardiology 20030315
Title: Inhibition of paclitaxel and baccatin III accumulation by mevinolin and fosmidomycin in suspension cultures of Taxus baccata.
Journal: Journal of biotechnology 20030306
Title: Determination of Simvastatin in human plasma by liquid chromatography-mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030305
Title: Three new drugs for hyperlipidemia.
Journal: The Medical letter on drugs and therapeutics 20030303
Title: Platelet derived growth factor-BB is a potent mitogen for rat ureteral and human bladder smooth muscle cells: dependence on lipid rafts for cell signaling.
Journal: The Journal of urology 20030301
Title: Mouse macrophage paraoxonase 2 activity is increased whereas cellular paraoxonase 3 activity is decreased under oxidative stress.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20030301
Title: Statin effects on cholesterol micro-domains in brain plasma membranes.
Journal: Biochemical pharmacology 20030301
Title: Effects of hypolipidemic treatment on serum markers of vascular inflammation in dyslipidemic men.
Journal: Medical science monitor : international medical journal of experimental and clinical research 20030301
Title: [Effects of lovastatin on proliferation and gap junctional intercellular communication of human breast cancer cell MCF-7].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20030301
Title: Treating dyslipidemia with statins: the risk-benefit profile.
Journal: American heart journal 20030301
Title: Comparative effects of lovastatin on mammary and prostate oncogenesis in transgenic mouse models.
Journal: Carcinogenesis 20030301
Title: A dose-ranging study of a new, once-daily, dual-component drug product containing niacin extended-release and lovastatin.
Journal: Clinical cardiology 20030301
Title: [Determination of total lovastatin in red rice].
Journal: Wei sheng yan jiu = Journal of hygiene research 20030301
Title: Regulation of osteoclast differentiation by statins.
Journal: Journal of musculoskeletal & neuronal interactions 20030301
Title: Lovastatin stimulates human vascular smooth muscle cell expression of bone morphogenetic protein-2, a potent inhibitor of low-density lipoprotein-stimulated cell growth.
Journal: Biochemical and biophysical research communications 20030227
Title: Efficacy and safety of ezetimibe coadministered with lovastatin in primary hypercholesterolemia.
Journal: The American journal of cardiology 20030215
Title: Inhibition of cdk2 activating phosphorylation by mevastatin.
Journal: The Journal of biological chemistry 20030214
Title: Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with ras hotspot mutations or overexpression.
Journal: Leukemia research 20030201
Title: Integrating transcriptional and metabolite profiles to direct the engineering of lovastatin-producing fungal strains.
Journal: Nature biotechnology 20030201
Title: Cholesterol is necessary both for the toxic effect of Abeta peptides on vascular smooth muscle cells and for Abeta binding to vascular smooth muscle cell membranes.
Journal: Journal of neurochemistry 20030201
Title: Inhibitor studies of isopentenyl pyrophosphate biosynthesis in suspension cultures of the yew Taxus chinensis var. mairei.
Journal: Biotechnology and applied biochemistry 20030201
Title: Statins can inhibit proliferation of human breast cancer cells in vitro.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20030201
Title: Transformations of cyclic nonaketides by Aspergillus terreus mutants blocked for lovastatin biosynthesis at the lovA and lovC genes.
Journal: Organic & biomolecular chemistry 20030107
Title: The synaptophysin/synaptobrevin interaction critically depends on the cholesterol content.
Journal: Journal of neurochemistry 20030101
Title: Cytochrome P450 drug interactions within the HMG-CoA reductase inhibitor class: are they clinically relevant?
Journal: Drug safety 20030101
Title: Niacin-ER and lovastatin treatment of hypercholesterolemia and mixed dyslipidemia.
Journal: The Annals of pharmacotherapy 20030101
Title: The ability of statins to inhibit bone resorption is directly related to their inhibitory effect on HMG-CoA reductase activity.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20030101
Title: HMG-CoA reductase inhibitors regulate inflammatory transcription factors in human endothelial and vascular smooth muscle cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20030101
Title: Synergistic activation of human LDL receptor expression by SCAP ligand and cytokine oncostatin M.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20030101
Title: Cerivastatin and atorvastatin inhibit IL-3-dependent differentiation and IgE-mediated histamine release in human basophils and downmodulate expression of the basophil-activation antigen CD203c/E-NPP3.
Journal: Journal of leukocyte biology 20030101
Title: Ubiquinone does not rescue acute myeloid leukemia cells from growth inhibition by statins.
Journal: Leukemia 20030101
Title: Blockade of HMG-CoA reductase activity causes changes in microtubule-stabilizing protein tau via suppression of geranylgeranylpyrophosphate formation: implications for Alzheimer's disease.
Journal: The European journal of neuroscience 20030101
Title: The statins as anticancer agents.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030101
Title: Comparing HMG-CoA reductase inhibitors.
Journal: Clinical cardiology 20030101
Title: Production of the secondary metabolites gamma-aminobutyric acid and monacolin K by Monascus.
Journal: Journal of industrial microbiology & biotechnology 20030101
Title: The role of the ubiquitination-proteasome pathway in breast cancer: applying drugs that affect the ubiquitin-proteasome pathway to the therapy of breast cancer.
Journal: Breast cancer research : BCR 20030101
Title: Effects of policosanol and lovastatin in patients with intermittent claudication: a double-blind comparative pilot study.
Journal: Angiology 20030101
Title: Cerivastatin: a cellular and molecular drug for the future?
Journal: Cellular and molecular life sciences : CMLS 20030101
Title: Production and purification of statins from Pleurotus ostreatus (Basidiomycetes) strains.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101
Title: An economic analysis of the Atorvastatin Comparative Cholesterol Efficacy and Safety Study (ACCESS).
Journal: PharmacoEconomics 20030101
Title: Lovastatin extended release: a review of its use in the management of hypercholesterolaemia.
Journal: Drugs 20030101
Title: Lopinavir/ritonavir: a review of its use in the management of HIV infection.
Journal: Drugs 20030101
Title: The role of intracellular cholesterol on the processing of the beta-amyloid precursor protein.
Journal: The journal of nutrition, health & aging 20030101
Title: Statins stimulate arachidonic acid release and prostaglandin I2 production in rat liver cells.
Journal: Lipids in health and disease 20030101
Title: Lymphocyte function-associated antigen-1 blockade by statins: molecular basis and biological relevance.
Journal: Endothelium : journal of endothelial cell research 20030101
Title: Does simvastatin stimulate bone formation in vivo?
Journal: BMC musculoskeletal disorders 20030101
Title: 4-hydroxycinnamate lowers plasma and hepatic lipids without changing antioxidant enzyme activities.
Journal: Annals of nutrition & metabolism 20030101
Title: Variable influence of statins on isoprostanes in hyperlipidemia.
Journal: Advances in experimental medicine and biology 20030101
Title: Melanoma chemoprevention: a role for statins or fibrates?
Journal: American journal of therapeutics 20030101
Title: Characterization of a non-pigment producing Monascus purpureus mutant strain.
Journal: Antonie van Leeuwenhoek 20030101
Title: Twice-daily amprenavir 1200 mg versus amprenavir 600 mg/ritonavir 100 mg, in combination with at least 2 other antiretroviral drugs, in HIV-1-infected patients.
Journal: BMC infectious diseases 20030101
Title: Hsp25 and Hsp70 in rodent tumors treated with doxorubicin and lovastatin.
Journal: Cell stress & chaperones 20030101
Title: HMG-CoA reductase inhibitors inhibit inducible nitric oxide synthase gene expression in macrophages.
Journal: Journal of biomedical science 20030101
Title: Potential nontraditional applications of statins.
Journal: The Annals of pharmacotherapy 20030101
Title: Comparison of the cholesterol-lowering effects and toxicity of D-003 and lovastatin in normocholesterolaemic rabbits.
Journal: Drugs in R&D 20030101
Title: Microencapsulation of lipid nanoparticles containing lipophilic drug.
Journal: Journal of microencapsulation 20030101
Title: Effect of statins combined with estradiol on the proliferation of human receptor-positive and receptor-negative breast cancer cells.
Journal: Menopause (New York, N.Y.) 20030101
Title: HMG-CoA reductase inhibition aborts functional differentiation and triggers apoptosis in cultured primary human monocytes: a potential mechanism of statin-mediated vasculoprotection.
Journal: BMC cardiovascular disorders 20030101
Title: HIV protease inhibitors and dyslipidemia.
Journal: AIDS reviews 20030101
Title: Natural products of the medicinal fungus Ganoderma lucidum: occurrence, biological activities, and pharmacological functions.
Journal: Chemical record (New York, N.Y.) 20030101
Title: Cholesterol-lowering action of policosanol compares well to that of pravastatin and lovastatin.
Journal: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20030101
Title: A review of anabolic therapies for osteoporosis.
Journal: Arthritis research & therapy 20030101
Title: Clinical pharmacokinetics of statins.
Journal: Methods and findings in experimental and clinical pharmacology 20030101
Title: Behavioral implications of lowering cholesterol levels: a double-blind pilot study.
Journal: Psychosomatics 20030101
Title: Novel small molecule cyclin-dependent kinases modulators in human clinical trials.
Journal: Cancer biology & therapy 20030101
Title: Molecular regulation of cholesterol biosynthesis: implications in carcinogenesis.
Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20030101
Title: Pharmacological comparison of the statins.
Journal: Arzneimittel-Forschung 20030101
Title: Cinnamate supplementation enhances hepatic lipid metabolism and antioxidant defense systems in high cholesterol-fed rats.
Journal: Journal of medicinal food 20030101
Title: Selective inhibition of cancer cell invasion by a geranylgeranyltransferase-I inhibitor.
Journal: Clinical & experimental metastasis 20030101
Title: Once-daily niacin extended release/lovastatin combination tablet has more favorable effects on lipoprotein particle size and subclass distribution than atorvastatin and simvastatin.
Journal: Preventive cardiology 20030101
Title: Weight uniformity of split tablets required by a Veterans Affairs policy.
Journal: Journal of managed care pharmacy : JMCP 20030101
Title: The safety of over-the-counter niacin. A randomized placebo-controlled trial [ISRCTN18054903].
Journal: BMC clinical pharmacology 20030101
Title: Ezetimibe: a first-in-class, novel cholesterol absorption inhibitor.
Journal: Cardiovascular drug reviews 20030101
Title: Statin stimulates bone morphogenetic protein-2, aggrecan, and type 2 collagen gene expression and proteoglycan synthesis in rat chondrocytes.
Journal: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20030101
Title: Hypergravity-induced changes in gene expression in Arabidopsis hypocotyls.
Journal: Advances in space research : the official journal of the Committee on Space Research (COSPAR) 20030101
Title: Cholesterol regulates ABCD2 gene expression: implications for X-linked adrenoleukodstrophy.
Journal: Advances in experimental medicine and biology 20030101
Title: [Screening of natural immunosuppressors by their ability to modify steroid synthesis in hepatocytes].
Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101
Title: Differences between lovastatin and simvastatin hydrolysis in healthy male and female volunteers:gut hydrolysis of lovastatin is twice that of simvastatin.
Journal: TheScientificWorldJournal 20030101
Title: Statins in hypercholesterolaemia: a dose-specific meta-analysis of lipid changes in randomised, double blind trials.
Journal: BMC family practice 20030101
Title: [Flotation mass-spectra and surface potential of low density lipoprotein particles of hyperlipidemic patients after forced abolishment of lavostatin treatment].
Journal: Biomeditsinskaia khimiia 20030101
Title: Statin inhibits interferon-gamma-induced expression of intercellular adhesion molecule-1 (ICAM-1) in vascular endothelial and smooth muscle cells.
Journal: Experimental & molecular medicine 20021231
Title: Receptor-dependent regulation of the CYP3A4 gene.
Journal: Toxicology 20021227
Title: Secretion of apolipoprotein E by brain glia requires protein prenylation and is suppressed by statins.
Journal: Brain research 20021220
Title: 2002 Alfred Burger Award Address in Medicinal Chemistry. Natural products and design: interrelated approaches in drug discovery.
Journal: Journal of medicinal chemistry 20021219
Title: Chelation-controlled reduction: stereoselective formation of syn-1,3-diols and synthesis of compactin and mevinolin lactone.
Journal: The Journal of organic chemistry 20021213
Title: Production of lovastatin examined by an integrated approach based on chemometrics and DOSY-NMR.
Journal: Biotechnology and bioengineering 20021205
Title: Regulation of CYP2B6 and CYP3A expression by hydroxymethylglutaryl coenzyme A inhibitors in primary cultured human hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20021201
Title: Monocarboxylate transporter mediates uptake of lovastatin acid in rat cultured mesangial cells.
Journal: Journal of pharmaceutical sciences 20021201
Title: Mevalonic acid partially restores chloroplast and etioplast development in Arabidopsis lacking the non-mevalonate pathway.
Journal: Planta 20021201
Title: X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha.
Journal: Structure (London, England : 1993) 20021201
Title: Niacin extended-release/lovastatin: combination therapy for lipid disorders.
Journal: Expert opinion on pharmacotherapy 20021201
Title: Origin of the epidermal calcium gradient: regulation by barrier status and role of active vs passive mechanisms.
Journal: The Journal of investigative dermatology 20021201
Title: Cerivastatin, a HMG-CoA reductase inhibitor, reduces plasminogen activator inhibitor-1 (PAI-1) expression in endothelial cells by down-regulation of cellular signaling and the inhibition of PAI-1 promoter activity.
Journal: Japanese journal of pharmacology 20021201
Title: Amyloplast formation in cultured tobacco BY-2 cells requires a high cytokinin content.
Journal: Plant & cell physiology 20021201
Title: An examination of the effect of cytochrome P450 drug interactions of hydroxymethylglutaryl-coenzyme A reductase inhibitors on health care utilization: a Canadian population-based study.
Journal: Clinical therapeutics 20021201
Title: Enzyme inhibitors to increase poly-3-hydroxybutyrate production by transgenic tobacco.
Journal: Bioscience, biotechnology, and biochemistry 20021201
Title: Toward a role for statins in immunomodulation.
Journal: Molecular interventions 20021201
Title: [Treatment with statins: further data from the Heart Protection Study].
Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20021130
Title: Side effects of statins--prevalence, relevance, consequences.
Journal: Wiener klinische Wochenschrift 20021130
Title: Statin-induced myositis migrans.
Journal: Wiener klinische Wochenschrift 20021130
Title: Immunomodulation of experimental autoimmune encephalomyelitis in the Lewis rats by Lovastatin.
Journal: Neuroscience letters 20021129
Title: Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of gibberellins in Arabidopsis.
Journal: The Journal of biological chemistry 20021122
Title: Combination therapy for combined dyslipidemia.
Journal: The American journal of cardiology 20021120
Title: Isoprenoids influence expression of Ras and Ras-related proteins.
Journal: Biochemistry 20021119
Title: The effects of lovastatin and simvastatin on the diurnal periodicity of plasma mevalonate concentrations in patients with heterozygous familial hypercholesterolemia.
Journal: Atherosclerosis 20021101
Title: Early statin therapy for acute coronary syndromes.
Journal: The Annals of pharmacotherapy 20021101
Title: In response to Furst et al, 'Possible association of QTc interval prolongation with co-administration of quetiapine and lovastatin'.
Journal: Biological psychiatry 20021101
Title: Role of the cholesterol biosynthetic pathway in osteoblastic differentiation of marrow stromal cells.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20021101
Title: Simvastatin improves fracture healing in mice.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20021101
Title: Lipid-lowering therapy after coronary artery bypass grafting: time for more aggressive intervention.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20021101
Title: Functional analysis of mlcR, a regulatory gene for ML-236B (compactin) biosynthesis in Penicillium citrinum.
Journal: Molecular genetics and genomics : MGG 20021101
Title: Lovastatin does not accentuate but is rather additive to palmitate-induced apoptosis in cardiomyocytes.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20021101
Title: Geranylgeranyl pyrophosphate counteracts the cataractogenic effect of lovastatin on cultured rat lenses.
Journal: Experimental eye research 20021101
Title: Preclinical pharmacokinetics of statins.
Journal: Methods and findings in experimental and clinical pharmacology 20021101
Title: Rhabdomyolysis due to red yeast rice (Monascus purpureus) in a renal transplant recipient.
Journal: Transplantation 20021027
Title: Mutant K-ras oncogene regulates steroidogenesis of normal human adrenocortical cells by the RAF-MEK-MAPK pathway.
Journal: British journal of cancer 20021021
Title: Cholesterol regulates ABCD2 expression: implications for the therapy of X-linked adrenoleukodystrophy.
Journal: Human molecular genetics 20021015
Title: Statins as immunomodulators: comparison with interferon-beta 1b in MS.
Journal: Neurology 20021008
Title: Comparing the effects of five different statins on the HDL subpopulation profiles of coronary heart disease patients.
Journal: Atherosclerosis 20021001
Title: Potent suppression of proliferation of a10 vascular smooth muscle cells by combined treatment with lovastatin and 3-allylfarnesol, an inhibitor of protein farnesyltransferase.
Journal: The Journal of pharmacology and experimental therapeutics 20021001
Title: Inhibition of glucose- and calcium-induced insulin secretion from betaTC3 cells by novel inhibitors of protein isoprenylation.
Journal: The Journal of pharmacology and experimental therapeutics 20021001
Title: A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system.
Journal: The Journal of pharmacology and experimental therapeutics 20021001
Title: The HMG-CoA reductase inhibitor lovastatin protects cells from the antineoplastic drugs doxorubicin and etoposide.
Journal: International journal of molecular medicine 20021001
Title: Rhabdomyolysis with concurrent atorvastatin and diltiazem.
Journal: The Annals of pharmacotherapy 20021001
Title: Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, are able to reduce superoxide anion production by NADPH oxidase in THP-1-derived monocytes.
Journal: Journal of cardiovascular pharmacology 20021001
Title: Statin-associated myopathy with normal creatine kinase levels.
Journal: Annals of internal medicine 20021001
Title: Summaries for patients. Muscle abnormalities in four patients taking statins to treat unfavorable cholesterol levels.
Journal: Annals of internal medicine 20021001
Title: On-line analysis of the (13)CO(2) labeling of leaf isoprene suggests multiple subcellular origins of isoprene precursors.
Journal: Planta 20021001
Title: Frequency of new coronary events in older persons with peripheral arterial disease and serum low-density lipoprotein cholesterol > or = 125 mg/dl treated with statins versus no lipid-lowering drug.
Journal: The American journal of cardiology 20021001
Title: The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism.
Journal: Endocrine reviews 20021001
Title: Plasma membrane cholesterol controls the cytotoxicity of Alzheimer's disease AbetaP (1-40) and (1-42) peptides.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001
Title: Lack of isoprenoid products raises ex vivo interleukin-1beta secretion in hyperimmunoglobulinemia D and periodic fever syndrome.
Journal: Arthritis and rheumatism 20021001
Title: [Effect of lovastatin on proliferation and extracellular matrix secretion of rat hepatic stellate cells in vitro].
Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20021001
Title: Lovastatin alters biliary lipid composition and dissolves gallstones: a long-term study in prairie dogs.
Journal: Digestive diseases and sciences 20021001
Title: Lovastatin-stimulated superinduction of E-selectin, ICAM-1 and VCAM-1 in TNF-alpha activated human vascular endothelial cells.
Journal: Atherosclerosis 20020901
Title: Influence of atorvastatin and simvastatin on apolipoprotein B metabolism in moderate combined hyperlipidemic subjects with low VLDL and LDL fractional clearance rates.
Journal: Atherosclerosis 20020901
Title: Clinical implications of statin event trials.
Journal: Current atherosclerosis reports 20020901
Title: Mechanisms of NOS2 regulation by Rho GTPase signaling in airway epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20020901
Title: Mitomycin C induces apoptosis and caspase-8 and -9 processing through a caspase-3 and Fas-independent pathway.
Journal: Cell death and differentiation 20020901
Title: The effects of lovastatin on proteasome activities in highly purified rabbit 20 S proteasome preparations and mouse MC3T3-E1 osteoblastic cells.
Journal: Metabolism: clinical and experimental 20020901
Title: Policosanol safely down-regulates HMG-CoA reductase - potential as a component of the Esselstyn regimen.
Journal: Medical hypotheses 20020901
Title: Update on the management of dyslipidemia.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020901
Title: Niacin-based therapy for dyslipidemia: past evidence and future advances.
Journal: The American journal of managed care 20020901
Title: Effect of increased dosage of the ML-236B (compactin) biosynthetic gene cluster on ML-236B production in Penicillium citrinum.
Journal: Molecular genetics and genomics : MGG 20020901
Title: Management of dyslipidemia in the primary prevention of coronary heart disease.
Journal: Current opinion in cardiology 20020901
Title: Cholesterol attenuates the membrane perturbing properties of beta-amyloid peptides.
Journal: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20020901
Title: Diabetes and the role of isoprenoid biosynthesis.
Journal: FEBS letters 20020814
Title: Lovastatin downregulates renal myofibroblast function in vitro.
Journal: Nephron 20020801
Title: Reduction of bFGF-induced smooth muscle cell proliferation and endothelin receptor mRNA expression by mevastatin and atorvastatin.
Journal: Biochemical pharmacology 20020801
Title: Pharmacology of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins), including rosuvastatin and pitavastatin.
Journal: Journal of clinical pharmacology 20020801
Title: HMG-CoA reductase inhibition and PPAR- alpha activation both inhibit cyclosporin A induced endothelin-1 secretion in cultured endothelial cells.
Journal: Clinical science (London, England : 1979) 20020801
Title: Cholesterol and Alzheimer's disease.
Journal: Biochemical Society transactions 20020801
Title: Proteome analysis of Aspergillus nidulans reveals proteins associated with the response to the antibiotic concanamycin A, produced by Streptomyces species.
Journal: Molecular genetics and genomics : MGG 20020801
Title: Determination of lovastatin and simvastatin in pharmaceutical dosage forms by MEKC.
Journal: Journal of pharmaceutical and biomedical analysis 20020720
Title: Targeting the cell cycle for cancer therapy.
Journal: British journal of cancer 20020715
Title: Simvastatin, an HMG-CoA reductase inhibitor, induces the synthesis and secretion of apolipoprotein AI in HepG2 cells and primary hamster hepatocytes.
Journal: Atherosclerosis 20020701
Title: Microarray and biochemical analysis of lovastatin-induced apoptosis of squamous cell carcinomas.
Journal: Neoplasia (New York, N.Y.) 20020701
Title: Long-term prevention of premature coronary atherosclerosis in homozygous familial hypercholesterolemia.
Journal: The Journal of pediatrics 20020701
Title: The cholesterol lowering drug lovastatin induces cell death in myeloma plasma cells.
Journal: Leukemia 20020701
Title: Alterations in membrane-bound and cytoplasmic K-ras protein levels in mouse lung induced by treatment with lovastatin, cholestyramine, or niacin: effects are highly mouse strain dependent.
Journal: Biochemical pharmacology 20020701
Title: Lovastatin potentiates antitumor activity of doxorubicin in murine melanoma via an apoptosis-dependent mechanism.
Journal: International journal of cancer 20020701
Title: Molecular cloning and characterization of an ML-236B (compactin) biosynthetic gene cluster in Penicillium citrinum.
Journal: Molecular genetics and genomics : MGG 20020701
Title: Lovastatin increases longitudinal bone growth and bone morphogenetic protein-2 levels in the growth plate of Sprague-Dawley rats.
Journal: European journal of pediatrics 20020701
Title: Inhibition of Rho-kinase induces alphaB-crystallin expression in lens epithelial cells.
Journal: Biochemical and biophysical research communications 20020628
Title: The liver and lovastatin.
Journal: The American journal of cardiology 20020615
Title: By the way, doctor. I read that they're now selling a cheaper version of Mevacor. But I've also heard that Mevacor isn't as effective as the other statins. What do you think?
Journal: Harvard health letter 20020601
Title: Mevastatin induces degeneration and decreases viability of cAMP-induced differentiated neuroblastoma cells in culture by inhibiting proteasome activity, and mevalonic acid lactone prevents these effects.
Journal: Journal of neuroscience research 20020601
Title: A clinical and experimental study on the protective effects of jiangzhi tongmai fang on endothelial injury.
Journal: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20020601
Title: Policosanol: a new treatment for cardiovascular disease?
Journal: Alternative medicine review : a journal of clinical therapeutic 20020601
Title: P-glycoprotein in acute myeloid leukaemia: therapeutic implications of its association with both a multidrug-resistant and an apoptosis-resistant phenotype.
Journal: Leukemia & lymphoma 20020601
Title: A randomized, double-blind comparison of cerivastatin and lovastatin for treatment of primary hypercholesterolemia.
Journal: Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 20020601
Title: Lovastatin induces cell death in cardiomyocytes that is not reversible by coenzyme Q 10.
Journal: Pharmacology & toxicology 20020601
Title: Comparison of effect of intensive lipid lowering with atorvastatin to less intensive lowering with lovastatin on C-reactive protein in patients with stable angina pectoris and inducible myocardial ischemia.
Journal: The American journal of cardiology 20020515
Title: Statins and risk of polyneuropathy: a case-control study.
Journal: Neurology 20020514
Title: Low- and high-density lipoprotein cholesterol and ischemic cerebrovascular disease: the bezafibrate infarction prevention registry.
Journal: Archives of internal medicine 20020513
Title: Rho activity can alter the translation of p27 mRNA and is important for RasV12-induced transformation in a manner dependent on p27 status.
Journal: The Journal of biological chemistry 20020510
Title: Inhibition of protein geranylgeranylation and RhoA/RhoA kinase pathway induces apoptosis in human endothelial cells.
Journal: The Journal of biological chemistry 20020503
Title: Rhabdomyolysis after concomitant use of cyclosporine, simvastatin, gemfibrozil, and itraconazole.
Journal: The Annals of pharmacotherapy 20020501
Title: Pharmacokinetics of lovastatin extended-release dosage form (Lovastatin XL) in healthy volunteers.
Journal: Biopharmaceutics & drug disposition 20020501
Title: Immunosuppressive effects of statins.
Journal: Atherosclerosis. Supplements 20020501
Title: Pharmacological interactions of statins.
Journal: Atherosclerosis. Supplements 20020501
Title: Diabetic dyslipidemia.
Journal: Atherosclerosis. Supplements 20020501
Title: The choice of hormone replacement therapy or statin therapy in the treatment of hyperlipidemic postmenopausal women.
Journal: Atherosclerosis. Supplements 20020501
Title: Quercetin dihydrate and gallate supplements lower plasma and hepatic lipids and change activities of hepatic antioxidant enzymes in high cholesterol-fed rats.
Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20020501
Title: Expression of Nedd5, a mammalian septin, in human brain tumors.
Journal: Journal of neuro-oncology 20020501
Title: Plasma homocysteine concentration, statin therapy, and the risk of first acute coronary events.
Journal: Circulation 20020416
Title: From the Food and Drug Administration.
Journal: JAMA 20020403
Title: Statins inhibit A beta-neurotoxicity in vitro and A beta-induced vasoconstriction and inflammation in rat aortae.
Journal: Atherosclerosis 20020401
Title: Lamin B, caspase-3 activity, and apoptosis induction by a combination of HMG-CoA reductase inhibitor and COX-2 inhibitors: a novel approach in developing effective chemopreventive regimens.
Journal: International journal of oncology 20020401
Title: CD43 polarization in unprimed T cells can be dissociated from raft coalescence by inhibition of HMG CoA reductase.
Journal: Blood 20020401
Title: Pharmacological concentrations of the HMG-CoA reductase inhibitor lovastatin decrease the formation of the Alzheimer beta-amyloid peptide in vitro and in patients.
Journal: Frontiers in bioscience : a journal and virtual library 20020401
Title: Effects of hypocholesterolaemic agents on the expression and activity of 3-hydroxy-3-methylglutaryl-CoA reductase in the fat body of the German cockroach.
Journal: Archives of insect biochemistry and physiology 20020401
Title: Biosynthesis and biotechnological production of statins by filamentous fungi and application of these cholesterol-lowering drugs.
Journal: Applied microbiology and biotechnology 20020401
Title: Withdrawal of statins increases event rates in patients with acute coronary syndromes.
Journal: Circulation 20020326
Title: Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB.
Journal: The Journal of biological chemistry 20020322
Title: Long-term safety and efficacy of a once-daily niacin/lovastatin formulation for patients with dyslipidemia.
Journal: The American journal of cardiology 20020315
Title: Myopathy and rhabdomyolysis with lipid-lowering drugs.
Journal: Toxicology letters 20020310
Title: Lovastatin enhances ecto-5'-nucleotidase activity and cell surface expression in endothelial cells: implication of rho-family GTPases.
Journal: Circulation research 20020308
Title: Managing dyslipidemia in the high-risk patient.
Journal: The American journal of cardiology 20020307
Title: Analytical method for monitoring concentrations of cyclosporin and lovastatin in vitro in an everted rat intestinal sac absorption model.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020305
Title: A novel concept to preserve the beneficial effects of hormone replacement therapy in bilaterally female ovariectomized rats: role of lovastatin therapy.
Journal: Pharmacological research 20020301
Title: 3-Morpholinosydnonimine hydrochloride induces p53-dependent apoptosis in murine primary neural cells: a critical role for p21(ras)-MAPK-p19(ARF) pathway.
Journal: Nitric oxide : biology and chemistry 20020301
Title: Effect of colesevelam on lovastatin pharmacokinetics.
Journal: The Annals of pharmacotherapy 20020301
Title: Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells.
Journal: Carcinogenesis 20020301
Title: Simvastatin and lovastatin, but not pravastatin, interact with MDR1.
Journal: The Journal of pharmacy and pharmacology 20020301
Title: Assessment of ADRs associated with lipid-lowering agents recorded in the Department of Internal Medicine, University Hospital, Jena.
Journal: International journal of clinical pharmacology and therapeutics 20020301
Title: C-reactive protein: from acute phase reactant to cardiovascular disease risk factor.
Journal: MLO: medical laboratory observer 20020301
Title: [Stimulation of bone formation by anti-hyperlipidemic agent statins and its mechanism of action].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20020301
Title: HMG-CoA reductase inhibitors reduce interleukin-6 synthesis in human vascular smooth muscle cells.
Journal: Cardiovascular drugs and therapy 20020301
Title: Antioxidant treatment of therapy-resistant idiopathic membranous nephropathy with probucol: a pilot study.
Journal: Wiener klinische Wochenschrift 20020227
Title: Potentiating antitumor effects of a combination therapy with lovastatin and butyrate in the Lewis lung carcinoma model in mice.
Journal: International journal of cancer 20020220
Title: Goals of statin conversion program.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020215
Title: Therapy and clinical trials.
Journal: Current opinion in lipidology 20020201
Title: Caveolae and cholesterol distribution in vascular smooth muscle cells of different phenotypes.
Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20020201
Title: Comparative pharmacokinetics of lovastatin extended-release tablets and lovastatin immediate-release tablets in humans.
Journal: Journal of clinical pharmacology 20020201
Title: 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis.
Journal: Gastroenterology 20020201
Title: Possible association of QTc interval prolongation with co-administration of quetiapine and lovastatin.
Journal: Biological psychiatry 20020201
Title: Antileukemia activity of perillyl alcohol (POH): uncoupling apoptosis from G0/G1 arrest suggests that the primary effect of POH on Bcr/Abl-transformed cells is to induce growth arrest.
Journal: Leukemia 20020201
Title: FDA adverse event reports on statin-associated rhabdomyolysis.
Journal: The Annals of pharmacotherapy 20020201
Title: The subcellular localization of an unusual rice calmodulin isoform, OsCaM61, depends on its prenylation status.
Journal: Plant molecular biology 20020201
Title: Farnesol and geranylgeraniol: prevention and reversion of lovastatin-induced effects in NIH3T3 cells.
Journal: Lipids 20020201
Title: Lipid-lowering long-term effects of six different statins in hypercholesterolemic renal transplant patients under cyclosporine immunosuppression.
Journal: Transplantation proceedings 20020201
Title: Distinct mechanisms of bisphosphonate action between osteoblasts and breast cancer cells: identity of a potent new bisphosphonate analogue.
Journal: Breast cancer research and treatment 20020201
Title: [Inhibitory effects of lovastatin on the proliferation and cell cycle phase of cultured human glomerular mesangial cells in vitro].
Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20020201
Title: Dose response, safety, and efficacy of an extended-release formulation of lovastatin in adults with hypercholesterolemia.
Journal: The American journal of cardiology 20020115
Title: A general assessment of the safety of HMG CoA reductase inhibitors (statins).
Journal: Current atherosclerosis reports 20020101
Title: Cyclin b1 promoter activity and functional cdk1 complex formation in G1 phase of human breast cancer cells.
Journal: Cell biology international 20020101
Title: HMG CoA reductase inhibitors affect the fibrinolytic system of human vascular cells in vitro: a comparative study using different statins.
Journal: British journal of pharmacology 20020101
Title: Cholesterol, essential fatty acids, and suicide.
Journal: Pharmacopsychiatry 20020101
Title: A multiple-dose pharmacodynamic, safety, and pharmacokinetic comparison of extended- and immediate-release formulations of lovastatin.
Journal: Clinical therapeutics 20020101
Title: Requirement of Rho-family GTPases in the invasion of Type 1-piliated uropathogenic Escherichia coli.
Journal: Cellular microbiology 20020101
Title: Effect of roxithromycin on the pharmacokinetics of lovastatin in volunteers.
Journal: European journal of clinical pharmacology 20020101
Title: [Schistosoma mansoni: the action of lovastatin on the murine model].
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20020101
Title: Effect of simvastatin on bone markers in osteopenic women: a placebo-controlled, dose-ranging trial [ISRCTN85429598].
Journal: BMC musculoskeletal disorders 20020101
Title: Morphologic change and elevation of cortisol secretion in cultured human normal adrenocortical cells caused by mutant p21K-ras protein.
Journal: DNA and cell biology 20020101
Title: Advicor (niacin extended-release and lovastatin tablets).
Journal: Journal of clinical hypertension (Greenwich, Conn.) 20020101
Title: The farnesyl transferase inhibitor RPR-130401 does not alter radiation susceptibility in human tumor cells with a K-Ras mutation in spite of large changes in ploidy and lamin B distribution.
Journal: BMC pharmacology 20020101
Title: Lovastatin and extended-release niacin combination product: the first drug combination for the management of hyperlipidemia.
Journal: Heart disease (Hagerstown, Md.) 20020101
Title: Lovastatin is a potent inhibitor of meningioma cell proliferation: evidence for inhibition of a mitogen associated protein kinase.
Journal: Journal of neuro-oncology 20020101
Title: Statins as modulators of bone formation.
Journal: Arthritis research 20020101
Title: Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors.
Journal: Clinical pharmacokinetics 20020101
Title: Basic fibroblast growth factor mediated growth inhibition in breast cancer cells is independent of ras signaling pathway.
Journal: Oncology reports 20020101
Title: Synergistic interaction between highly specific cyclooxygenase-2 inhibitor, MF-tricyclic and lovastatin in murine colorectal cancer cell lines.
Journal: Oncology reports 20020101
Title: Food-drug interactions.
Journal: Drugs 20020101
Title: The role of statins as potential targets for bone formation.
Journal: Arthritis research 20020101
Title: Insights into integrin-ligand binding and activation from the first crystal structure.
Journal: Arthritis research 20020101
Title: [Myopathy due to statins, a dose-dependent effect, and of what kind?].
Journal: Atencion primaria 20020101
Title: Reappraisal of G1-phase arrest and synchronization by lovastatin.
Journal: Cell biology international 20020101
Title: Oxidation injury in patients receiving HMG-CoA reductase inhibitors: occurrence in patients without enzyme elevation or myopathy.
Journal: Drug safety 20020101
Title: [Concentration on Diapak C 16 capsules of lovastatin, mevinolinic acid and other inhibitors of biosynthesis of sterins produced by Penicillium citrinum 89].
Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20020101
Title: Mevastatin, an inhibitor of HMG-CoA reductase, induces apoptosis, differentiation and Rap1 expression in HL-60 cells.
Journal: Physiological chemistry and physics and medical NMR 20020101
Title: Lovastatin alters cytoskeleton organization and inhibits experimental metastasis of mammary carcinoma cells.
Journal: Clinical & experimental metastasis 20020101
Title: Interactions between antiretroviral drugs and drugs used for the therapy of the metabolic complications encountered during HIV infection.
Journal: Clinical pharmacokinetics 20020101
Title: Benefits and menaces related to the use of statins in patients after renal transplantation.
Journal: Annals of transplantation 20020101
Title: Statins and menopause.
Journal: Drugs 20020101
Title: Enhanced sensitivity of G1 arrested human cancer cells suggests a novel therapeutic strategy using a combination of simvastatin and TRAIL.
Journal: Cell cycle (Georgetown, Tex.) 20020101
Title: A multidisciplinary program for achieving lipid goals in chronic hemodialysis patients.
Journal: BMC nephrology 20020101
Title: The effect of Puerariae radix on lipoprotein metabolism in liver and intestinal cells.
Journal: BMC complementary and alternative medicine 20020101
Title: The discovery and development of atorvastatin, a potent novel hypolipidemic agent.
Journal: Progress in medicinal chemistry 20020101
Title: Effects of nicotinic acid and lovastatin in combination with cholestyramine in renal transplant patients.
Journal: Missouri medicine 20020101
Title: Effect of rice--glycerol complex medium on the production of Lovastatin by Monascus ruber.
Journal: Folia microbiologica 20020101
Title: Effects of policosanol and lovastatin on lipid profile and lipid peroxidation in patients with dyslipidemia associated with type 2 diabetes mellitus.
Journal: International journal of clinical pharmacology research 20020101
Title: The eye lens evaluation of the atorvastatin-treated white rat.
Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20020101
Title: Effects of a tablet-splitting program in patients taking HMG-CoA reductase inhibitors: analysis of clinical effects, patient satisfaction, compliance, and cost avoidance.
Journal: Journal of managed care pharmacy : JMCP 20020101
Title: Management of protease inhibitor-associated hyperlipidemia.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101
Title: Application of oxygen vectors to Aspergillus terreus cultivation.
Journal: Journal of bioscience and bioengineering 20020101
Title: Modulation of COX-2 expression by statins in human aortic smooth muscle cells. Involvement of geranylgeranylated proteins.
Journal: The Journal of biological chemistry 20011214
Title: Phosphatidylinositol 3-kinase and Ras/mitogen-activated protein kinase signaling pathways are required for the regulation of 5-aminolevulinate synthase gene expression by insulin.
Journal: Experimental cell research 20011210
Title: Diels-Alderases.
Journal: Chembiochem : a European journal of chemical biology 20011203
Title: Naringin has an antiatherogenic effect with the inhibition of intercellular adhesion molecule-1 in hypercholesterolemic rabbits.
Journal: Journal of cardiovascular pharmacology 20011201
Title: Diverse effects of inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase on the expression of VCAM-1 and E-selectin in endothelial cells.
Journal: The Biochemical journal 20011201
Title: Lipid-lowering and antioxidative activities of 3,4-di(OH)-cinnamate and 3,4-di(OH)-hydrocinnamate in cholesterol-fed rats.
Journal: Clinica chimica acta; international journal of clinical chemistry 20011201
Title: Are there potential non-lipid-lowering uses of statins in the kidney?
Journal: Nephron 20011201
Title: Effect of atorvastatin, simvastatin, and lovastatin on the metabolism of cholesterol and triacylglycerides in HepG2 cells.
Journal: Biochemical pharmacology 20011201
Title: Alpha tocopheryl succinate, retinoic acid and polar carotenoids enhanced the growth-inhibitory effect of a cholesterol-lowering drug on immortalized and transformed nerve cells in culture.
Journal: Journal of the American College of Nutrition 20011201
Title: Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS): efficacy and tolerability of long-term treatment with lovastatin in women.
Journal: Journal of women's health & gender-based medicine 20011201
Title: Comparison of endothelial pleiotropic actions of angiotensin converting enzyme inhibitors and statins.
Journal: Annals of the New York Academy of Sciences 20011201
Title: Synergistic interaction of lovastatin and paclitaxel in human cancer cells.
Journal: Molecular cancer therapeutics 20011201
Title: [Effects of lovastatin combined with cyclosporine A on cultured human peripheral blood mononuclear cells proliferation, cytokines expression and cytotoxicity].
Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20011201
Title: Impairment by lovastatin of neural relaxation of the rabbit sphincter of Oddi.
Journal: European journal of pharmacology 20011130
Title: Effect of an aggressive lipid-lowering strategy on progression of atherosclerosis in the left main coronary artery from patients in the post coronary artery bypass graft trial.
Journal: Circulation 20011127
Title: Regulation of hepatic lanosterol 14 alpha-demethylase gene expression by dietary cholesterol and cholesterol-lowering agents.
Journal: Archives of biochemistry and biophysics 20011115
Title: Comparative squalene synthase gene expression in mouse liver and testis.
Journal: Archives of biochemistry and biophysics 20011115
Title: CNS synaptogenesis promoted by glia-derived cholesterol.
Journal: Science (New York, N.Y.) 20011109
Title: Locking a leukocyte integrin with statins.
Journal: The New England journal of medicine 20011108
Title: Inhibition of isoprenoid biosynthesis causes insulin resistance in 3T3-L1 adipocytes.
Journal: FEBS letters 20011102
Title: Antioxidative activity of naringin and lovastatin in high cholesterol-fed rabbits.
Journal: Life sciences 20011102
Title: Lovastatin-induced apoptosis in thyroid cells: involvement of cytochrome c and lamin B.
Journal: European journal of endocrinology 20011101
Title: Lovastatin increases nitric oxide synthesis in IL-1 beta-stimulated smooth muscle cells.
Journal: Chinese medical journal 20011101
Title: Inflammatory mechanisms in atherosclerosis: from laboratory evidence to clinical application.
Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20011101
Title: [In vitro effect of lovastatin on NB4 promyelocytic leukemia cells].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20011101
Title: Effect of hydroxymethylglutaryl coenzyme a reductase inhibitors on the progression of calcific aortic stenosis.
Journal: Circulation 20011030
Title: The antiinflammatory effects of statins.
Journal: The New England journal of medicine 20011018
Title: The antiinflammatory effects of statins.
Journal: The New England journal of medicine 20011018
Title: [Can the action of statins reveal etiology of coronary diseases?].
Journal: Lakartidningen 20011017
Title: Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis.
Journal: Journal of neuroscience research 20011015
Title: beta-Oxidation of simvastatin in mouse liver preparations.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20011001
Title: Hyperlipidaemia and cardiovascular disease.
Journal: Current opinion in lipidology 20011001
Title: Lovastatin-induced E2F-1 modulation and its effect on prostate cancer cell death.
Journal: Carcinogenesis 20011001
Title: Lovastatin-induced cytoskeletal reorganization in lens epithelial cells: role of Rho GTPases.
Journal: Investigative ophthalmology & visual science 20011001
Title: The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, ezetimibe, in combination with 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors in dogs.
Journal: Metabolism: clinical and experimental 20011001
Title: Regulation of sterol regulatory element-binding proteins by cholesterol flux in CaCo-2 cells.
Journal: Journal of lipid research 20011001
Title: Effects of prolonged intensive lipid-lowering therapy on the characteristics of carotid atherosclerotic plaques in vivo by MRI: a case-control study.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20011001
Title: Biosynthetic pathway of insect juvenile hormone III in cell suspension cultures of the sedge Cyperus iria.
Journal: Plant physiology 20011001
Title: [Cholesterol, omega-3 fatty acids, and suicide risk: empirical evidence and pathophysiological hypotheses].
Journal: Fortschritte der Neurologie-Psychiatrie 20011001
Title: Managed care trends in statin usage.
Journal: Managed care (Langhorne, Pa.) 20011001
Title: Statins in children. Why and when.
Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20011001
Title: Safety and efficacy of treatment of children and adolescents with elevated low density lipoprotein levels with a step two diet or with lovastatin.
Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20011001
Title: Apolipoprotein E genotype affects plasma lipid response to atorvastatin in a gender specific manner.
Journal: Atherosclerosis 20010901
Title: CFTR modulates programmed cell death by decreasing intracellular pH in Chinese hamster lung fibroblasts.
Journal: American journal of physiology. Cell physiology 20010901
Title: Mechanism of up-regulated gap junctional intercellular communication during chemoprevention and chemotherapy of cancer.
Journal: Mutation research 20010901
Title: Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells.
Journal: Leukemia 20010901
Title: Simvastatin-diltiazem drug interaction resulting in rhabdomyolysis and hepatitis.
Journal: Tennessee medicine : journal of the Tennessee Medical Association 20010901
Title: Effects of lovastatin and pravastatin on cognitive function in military aircrew.
Journal: Aviation, space, and environmental medicine 20010901
Title: Smoking diminishes the beneficial effect of statins: observations from the landmark trials.
Journal: Angiology 20010901
Title: C-reactive protein, coronary risk, and statins.
Journal: Harvard women's health watch 20010901
Title: Oxidation of lovastatin in the solid state and its stabilization with natural antioxidants.
Journal: Die Pharmazie 20010901
Title: Lipophilic statins can be osteogenic by promoting osteoblastic calcification in a Cbfa1- and BMP-2-independent manner.
Journal: Methods and findings in experimental and clinical pharmacology 20010901
Title: Statins in the 21st century: end of the simple story?
Journal: Expert opinion on investigational drugs 20010901
Title: In vitro antitumor activity of cerivastatin, a novel and potent HMG-CoA reductase inhibitor.
Journal: FEBS letters 20010817
Title: Efficient antitumor immunity derived from maturation of dendritic cells that had phagocytosed apoptotic/necrotic tumor cells.
Journal: International journal of cancer 20010815
Title: Achieving and maintaining National Cholesterol Education Program low-density lipoprotein cholesterol goals with five statins.
Journal: The American journal of medicine 20010815
Title: Interaction of cytosine arabinoside and lovastatin in human leukemia cells.
Journal: Leukemia research 20010801
Title: The widening role of statins: RAS signal transduction and drug-induced cytotoxicity in human leukemia: a commentary to 'interaction of cytosine arabinoside and lovastatin in human leukemia cells'.
Journal: Leukemia research 20010801
Title: Neuroprotective signal transduction in model motor neurons exposed to thrombin: G-protein modulation effects on neurite outgrowth, Ca(2+) mobilization, and apoptosis.
Journal: Journal of neurobiology 20010801
Title: Effect of perillic acid, a putative isoprenylation inhibitor, on the cultured rat lens.
Journal: Experimental eye research 20010801
Title: Correlation of non-high-density lipoprotein cholesterol with apolipoprotein B: effect of 5 hydroxymethylglutaryl coenzyme A reductase inhibitors on non-high-density lipoprotein cholesterol levels.
Journal: The American journal of cardiology 20010801
Title: Action of an HMG CoA reductase inhibitor, lovastatin, on apoptosis of untransformed and ts-SV40 transformed human smooth muscle cells derived from saphenous vein.
Journal: Journal of cardiovascular pharmacology 20010801
Title: Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins).
Journal: British journal of pharmacology 20010801
Title: Possible relationship between statin use and decreased incidence of dementia: are we ready for a new indication for these drugs?
Journal: Archives of internal medicine 20010801
Title: Pleiotropic effects of statins: do they matter?
Journal: Current opinion in lipidology 20010801
Title: By the way, doctor... My brother takes Mevacor and has been told to take the drug at bedtime. But when I started on Lipitor, my doctor said to take the medication at any time of the day. Why the difference?
Journal: Harvard health letter 20010801
Title: Polyketide biosynthesis: a millennium review.
Journal: Natural product reports 20010801
Title: Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins).
Journal: European journal of clinical pharmacology 20010801
Title: Carboxyl-methylation of Rab3D in the rat pancreatic acinar tumor cell line AR42J.
Journal: Biochemical and biophysical research communications 20010720
Title: Coronary artery disease progression assessed by electron-beam computed tomography.
Journal: The American journal of cardiology 20010719
Title: HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2.
Journal: Carcinogenesis 20010701
Title: Lipophilic statins augment inducible nitric oxide synthase expression in cytokine-stimulated cardiac myocytes.
Journal: Journal of cardiovascular pharmacology 20010701
Title: Statins and dementia.
Journal: Archives of neurology 20010701
Title: Cerivastatin triggers tumor-specific apoptosis with higher efficacy than lovastatin.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20010701
Title: Essential fatty acids as possible mediators of the actions of statins.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20010701
Title: Statin therapy and stroke prevention.
Journal: Current opinion in cardiology 20010701
Title: The role of cytochrome P450-mediated drug-drug interactions in determining the safety of statins.
Journal: Expert opinion on pharmacotherapy 20010701
Title: Treatment of the elderly with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors: focus on drug interactions.
Journal: Journal of cardiovascular pharmacology and therapeutics 20010701
Title: Dose-dependent effects of lovastatin on cell cycle progression. Distinct requirement of cholesterol and non-sterol mevalonate derivatives.
Journal: Biochimica et biophysica acta 20010629
Title: Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events.
Journal: The New England journal of medicine 20010628
Title: Statins and the acute-phase response.
Journal: The New England journal of medicine 20010628
Title: The HDV large-delta antigen fused with GFP remains functional and provides for studying its dynamic distribution.
Journal: Virology 20010620
Title: Conversion of cyclic nonaketides to lovastatin and compactin by a lovC deficient mutant of Aspergillus terreus.
Journal: Bioorganic & medicinal chemistry letters 20010618
Title: Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors.
Journal: Cancer research 20010615
Title: Use of statins and the subsequent development of deep vein thrombosis.
Journal: Archives of internal medicine 20010611
Title: Compactin enhances osteogenesis in murine embryonic stem cells.
Journal: Biochemical and biophysical research communications 20010608
Title: Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site.
Journal: Nature medicine 20010601
Title: Effect of lovastatin, an HMG CoA reductase inhibitor, on acute renal allograft rejection.
Journal: Clinical transplantation 20010601
Title: Low-dose combination therapy with colesevelam hydrochloride and lovastatin effectively decreases low-density lipoprotein cholesterol in patients with primary hypercholesterolemia.
Journal: Clinical cardiology 20010601
Title: Statin therapy and the prevention of dementia.
Journal: Archives of neurology 20010601
Title: [Improvement of endothelial function in patients with hypercholesterolemia and normal coronary arteries with lipid-lowering therapy].
Journal: Revista espanola de cardiologia 20010601
Title: Inhibition of growth of methane-producing bacteria of the ruminant forestomach by hydroxymethylglutaryl-SCoA reductase inhibitors.
Journal: Journal of dairy science 20010601
Title: Plasmodium falciparum: the lethal effects of tunicamycin and mevastatin on the parasite are not mediated by the inhibition of N-linked oligosaccharide biosynthesis.
Journal: Experimental parasitology 20010601
Title: Treatment with controlled-release lovastatin decreases serum concentrations of human beta-amyloid (A beta) peptide.
Journal: The international journal of neuropsychopharmacology 20010601
Title: HMG-CoA reductase inhibitors (statins) characterized as direct inhibitors of P-glycoprotein.
Journal: Pharmaceutical research 20010601
Title: Chromatographic purification of some 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors.
Journal: Journal of chromatography. A 20010525
Title: Regulation of sterol regulatory element-binding proteins in hamster intestine by changes in cholesterol flux.
Journal: The Journal of biological chemistry 20010518
Title: RhoA is activated during respiratory syncytial virus infection.
Journal: Virology 20010510
Title: Cholesterol ester accumulation: an immediate consequence of acute in vivo ischemic renal injury.
Journal: Kidney international 20010501
Title: Can modulation of endothelial nitric oxide synthase explain the vasculoprotective actions of statins?
Journal: Trends in molecular medicine 20010501
Title: Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TEXCAPS): additional perspectives on tolerability of long-term treatment with lovastatin.
Journal: The American journal of cardiology 20010501
Title: The combined effects of novel tocotrienols and lovastatin on lipid metabolism in chickens.
Journal: Atherosclerosis 20010501
Title: Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozil but not by bezafibrate.
Journal: Clinical pharmacology and therapeutics 20010501
Title: Long-term administration of the HMG-CoA reductase inhibitor lovastatin in two patients with cholesteryl ester storage disease.
Journal: International journal of clinical pharmacology and therapeutics 20010501
Title: Should all patients with cardiovascular disease receive statin therapy?
Journal: The American journal of managed care 20010501
Title: Statins--similarities and differences.
Journal: The American journal of managed care 20010501
Title: What do the statin trials tell us?
Journal: The American journal of managed care 20010501
Title: Revised indications for statin therapies.
Journal: Angiology 20010501
Title: Statin induced myopathy does not show up in MIBI scintigraphy.
Journal: Nuclear medicine communications 20010501
Title: The National Service Framework on coronary heart disease: is it sufficiently evidence-based?
Journal: Annals of clinical biochemistry 20010501
Title: Statins and bone formation.
Journal: Current pharmaceutical design 20010501
Title: Inhibition of purified pig and human liver retinyl ester hydrolase by pharmacologic agents.
Journal: Lipids 20010501
Title: [Effect of monascus on improving the hemorheology of rats with high blood lipids].
Journal: Wei sheng yan jiu = Journal of hygiene research 20010501
Title: Methods for synchronizing cells at specific stages of the cell cycle.
Journal: Current protocols in cell biology 20010501
Title: Deterioration of the protein kinase C-K(ATP) channel pathway in regulation of coronary flow in hypercholesterolaemic rabbits.
Journal: European journal of pharmacology 20010427
Title: Analysis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors using liquid chromatography-electrospray mass spectrometry.
Journal: Journal of chromatography. B, Biomedical sciences and applications 20010425
Title: Differential effects of lovastatin treatment on brain cholesterol levels in normal and apoE-deficient mice.
Journal: Neuroreport 20010417
Title: Assessing the results: phase 1 hyperlipidemia outcomes in 27 health plans.
Journal: The American journal of medicine 20010416
Title: Statins are magic when you gotta have heart.
Journal: U.S. news & world report 20010416
Title: The biosynthetic incorporation of the intact leucine skeleton into sterol by the trypanosomatid Leishmania mexicana.
Journal: The Journal of biological chemistry 20010413
Title: Cell cycle-related changes in regulatory volume decrease and volume-sensitive chloride conductance in mouse fibroblasts.
Journal: Journal of cellular physiology 20010401
Title: Comparative study of HMG-CoA reductase inhibitors on fibrinogen.
Journal: Atherosclerosis 20010401
Title: Antiviral activity of lovastatin against respiratory syncytial virus in vivo and in vitro.
Journal: Antimicrobial agents and chemotherapy 20010401
Title: Rho GTPases are involved in the regulation of NF-kappaB by genotoxic stress.
Journal: Experimental cell research 20010401
Title: A new simvastatin (mevinolin)-resistance marker from Haloarcula hispanica and a new Haloferax volcanii strain cured of plasmid pHV2.
Journal: Microbiology (Reading, England) 20010401
Title: Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice.
Journal: Stroke 20010401
Title: The effects of the statins lovastatin and cerivastatin on signalling by the prostanoid IP-receptor.
Journal: British journal of pharmacology 20010401
Title: An analysis of nine proprietary Chinese red yeast rice dietary supplements: implications of variability in chemical profile and contents.
Journal: Journal of alternative and complementary medicine (New York, N.Y.) 20010401
Title: 3-Hydroxy-3-methylglutaryl coenzyme A synthase-1 of Blattella germanica has structural and functional features of an active retrogene.
Journal: Insect biochemistry and molecular biology 20010315
Title: High apolipoprotein B with low high-density lipoprotein cholesterol and normal plasma triglycerides and cholesterol.
Journal: The American journal of cardiology 20010315
Title: A comparison of the effects of 3-hydroxy-3-methylglutaryl-coenzyme a (HMG-CoA) reductase inhibitors on the CYP3A4-dependent oxidation of mexazolam in vitro.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010301
Title: HMG-CoA reductase inhibitors and P-glycoprotein modulation.
Journal: British journal of pharmacology 20010301
Title: Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of human farnesyltransferase, BIM-46228.
Journal: International journal of cancer 20010301
Title: Lovastatin and phenylacetate induce apoptosis, but not differentiation, in human malignant glioma cells.
Journal: Acta neuropathologica 20010301
Title: Is a statin a statin?
Journal: International journal of clinical practice 20010301
Title: [Effect of cholesterol deficiency on the membrane fluidity of Jurkat T lymphocytes].
Journal: Wei sheng yan jiu = Journal of hygiene research 20010301
Title: Lovastatin blocks basic fibroblast growth factor-induced mitogen-activated protein kinase signaling in coronary smooth muscle cells via phosphatase inhibition.
Journal: European journal of cell biology 20010301
Title: [AFCAPS/TexCAPS [The Air Force/Texas Coronary Atherosclerosis Prevention Study]].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301
Title: [Statins do not prevent restenosis after coronary angioplasty: where to go from here?].
Journal: Herz 20010301
Title: Recent advances in the biosynthetic studies of lovastatin.
Journal: Current opinion in drug discovery & development 20010301
Title: Role of inhibitors of isoprenylation in proliferation, phenotype and apoptosis of human retinal pigment epithelium.
Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20010301
Title: A clinical focus on statins.
Journal: Current opinion in investigational drugs (London, England : 2000) 20010301
Title: [HMG-CoA reductase inhibitors and sexual dysfunction].
Journal: Anales de medicina interna (Madrid, Spain : 1984) 20010301
Title: Butyrate-induced differentiation of Caco-2 cells occurs independently from p27.
Journal: Biochemical and biophysical research communications 20010223
Title: Common hepatic lipase gene promoter variant determines clinical response to intensive lipid-lowering treatment.
Journal: Circulation 20010213
Title: Nitrogen-bisphosphonates block retinoblastoma phosphorylation and cell growth by inhibiting the cholesterol biosynthetic pathway in a keratinocyte model for esophageal irritation.
Journal: Molecular pharmacology 20010201
Title: Vascular effects of HMG CoA-reductase inhibitors (statins) unrelated to cholesterol lowering: new concepts for cardiovascular disease.
Journal: Cardiovascular research 20010201
Title: Cholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol delta8-isomerase, a cholesterogenic enzyme with multiple functions.
Journal: The Biochemical journal 20010201
Title: Bimonthly update. Therapy and clinical trials.
Journal: Current opinion in lipidology 20010201
Title: Lovastatin induces apoptosis of spontaneously immortalized rat brain neuroblasts: involvement of nonsterol isoprenoid biosynthesis inhibition.
Journal: Molecular and cellular neurosciences 20010201
Title: Mechanisms for cholesterol homeostasis in rat jejunal mucosa: effects of cholesterol, sitosterol, and lovastatin.
Journal: Journal of lipid research 20010201
Title: Do HMG-CoA reductase inhibitors affect fibrinogen?
Journal: The Annals of pharmacotherapy 20010201
Title: [Statins: a major therapeutic breakthrough].
Journal: Annales d'endocrinologie 20010201
Title: [Mechanisms of action of statins and their pleiotropic effects].
Journal: Annales d'endocrinologie 20010201
Title: [Statins and stroke].
Journal: Annales d'endocrinologie 20010201
Title: [Kidney and statins].
Journal: Annales d'endocrinologie 20010201
Title: [Statins and diabetic hyperlipidemia].
Journal: Annales d'endocrinologie 20010201
Title: [Statins: intervention studies, facts and perspectives].
Journal: Annales d'endocrinologie 20010201
Title: [Practical questions for the expert].
Journal: Annales d'endocrinologie 20010201
Title: [Endocrine disease in adrenoleukodystrophy].
Journal: Annales de medecine interne 20010201
Title: Lovastatin induced control of blast cell growth in an elderly patient with acute myeloblastic leukemia.
Journal: Leukemia & lymphoma 20010201
Title: Metabolites of Monascus ruber in silages.
Journal: Journal of animal physiology and animal nutrition 20010201
Title: [The role of HDL in the prevention of cardiovascular events].
Journal: Orvosi hetilap 20010121
Title: [Metabolic interactions with statins].
Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20010120
Title: Heart disease. Rethinking treatments for the heart.
Journal: Time 20010115
Title: Effective use of statins to prevent coronary heart disease.
Journal: American family physician 20010115
Title: Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha).
Journal: Gene 20010110
Title: Apolipoprotein B versus lipoprotein lipids: vital lessons from the AFCAPS/TexCAPS trial.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20010109
Title: Statin trials in progress: unanswered questions.
Journal: Current atherosclerosis reports 20010101
Title: New statins and new doses of older statins.
Journal: Current atherosclerosis reports 20010101
Title: Statins in children: what do we know and what do we need to do?
Journal: Current atherosclerosis reports 20010101
Title: The benefits of niacin in atherosclerosis.
Journal: Current atherosclerosis reports 20010101
Title: Reduction of LDL cholesterol in patients with primary hypercholesterolemia by SCH 48461: results of a multicenter dose-ranging study.
Journal: Journal of clinical pharmacology 20010101
Title: Molecular effects of HMG-CoA reductase inhibitors on smooth muscle cell proliferation.
Journal: Journal of the American College of Cardiology 20010101
Title: Fragmentation study of simvastatin and lovastatin using electrospray ionization tandem mass spectrometry.
Journal: Journal of mass spectrometry : JMS 20010101
Title: Rhabdomyolysis secondary to a drug interaction between simvastatin and clarithromycin.
Journal: The Annals of pharmacotherapy 20010101
Title: Differential sensitivity of various pediatric cancers and squamous cell carcinomas to lovastatin-induced apoptosis: therapeutic implications.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20010101
Title: A comparative study of policosanol vs lovastatin on intimal thickening in rabbit cuffed carotid artery.
Journal: Pharmacological research 20010101
Title: Cholesterol-dependent modulation of tau phosphorylation in cultured neurons.
Journal: Journal of neurochemistry 20010101
Title: The cyclin dependent kinase inhibitor p27 and its prognostic role in breast cancer.
Journal: Breast cancer research : BCR 20010101
Title: Cost effectiveness of HMG-CoA reductase inhibition in Canada.
Journal: The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20010101
Title: Phase II study of high-dose lovastatin in patients with advanced gastric adenocarcinoma.
Journal: Investigational new drugs 20010101
Title: New OTC drugs and devices 2000: a selective review.
Journal: Journal of the American Pharmaceutical Association (Washington,D.C. : 1996) 20010101
Title: Liver regeneration after hepatectomy.
Journal: Hepato-gastroenterology 20010101
Title: Lovastatin controls signal transduction in vascular smooth muscle cells by modulating phosphorylation levels of mevalonate-independent pathways.
Journal: Basic research in cardiology 20010101
Title: Statin-stimulated nitric oxide release from endothelium.
Journal: Medical science monitor : international medical journal of experimental and clinical research 20010101
Title: Statin therapy.
Journal: Clinical medicine (London, England) 20010101
Title: Elevated baseline triglyceride levels modulate effects of HMGCoA reductase inhibitors on plasma lipoproteins.
Journal: Journal of cardiovascular pharmacology and therapeutics 20010101
Title: [Therapeutic and pleiotropic effects of statins in primary and secondary prevention of atherosclerosis].
Journal: Bulletin de l'Academie nationale de medecine 20010101
Title: Lipid-lowering medications: what the new guidelines and data mean to women.
Journal: The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia 20010101
Title: [Substantiation of increasing doses of statins in clinical practice].
Journal: Terapevticheskii arkhiv 20010101
Title: [Effects of pathogenetic therapy on blood cholesterol in patients with glomerulonephritis].
Journal: Terapevticheskii arkhiv 20010101
Title: Transplanted livers and kidneys for HIV+ people.
Journal: TreatmentUpdate 20010101
Title: Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy.
Journal: Molecular genetics and metabolism 20010101
Title: Melanoma.
Journal: The oncologist 20010101
Title: Atorvastatin: an updated review of its pharmacological properties and use in dyslipidaemia.
Journal: Drugs 20010101
Title: Using test dose challenges to restore essential therapy in patients with idiopathic anaphylaxis and pharmacophobia: report of a patient with idiopathic anaphylaxis and statin phobia.
Journal: Allergy and asthma proceedings 20010101
Title: Statins as immunomodulatory drugs.
Journal: Advances in experimental medicine and biology 20010101
Title: Some nutritional factors influencing mevinolin production by Aspergillus terreus strain.
Journal: Folia microbiologica 20010101
Title: If LDL-C is the answer...what was the question? What do the data really show?
Journal: Heart disease (Hagerstown, Md.) 20010101
Title: Colesevelam: a new bile acid sequestrant.
Journal: Heart disease (Hagerstown, Md.) 20010101
Title: Pneumocystis carinii f. sp. carinii synthesizes de novo four homologs of ubiquinone.
Journal: The Journal of eukaryotic microbiology 20010101
Title: Lovastatin inhibits phenylephrine-induced ERK activation and growth of cardiac.
Journal: Cardiovascular toxicology 20010101
Title: Colesevelam.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20010101
Title: Increased lipid peroxidation in a patient with CK-elevation and muscle pain during statin therapy.
Journal: Atherosclerosis 20001101
Title: Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein-associated lactonase and protects low density lipoprotein against oxidation.
Journal: The Journal of biological chemistry 20001027
Title: Inhibitors of sterol biosynthesis and amphotericin B reduce the viability of pneumocystis carinii f. sp. carinii.
Journal: Antimicrobial agents and chemotherapy 20000601
Title: Differences in the effects of HMG-CoA reductase inhibitors on proliferation and viability of smooth muscle cells in culture.
Journal: Atherosclerosis 20000601
Title: Compactin and simvastatin, but not pravastatin, induce bone morphogenetic protein-2 in human osteosarcoma cells.
Journal: Biochemical and biophysical research communications 20000519
Title: Lovastatin potentiates antitumor activity and attenuates cardiotoxicity of doxorubicin in three tumor models in mice.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20000501
Title: Does vitamin E beneficially affect muscle pains during HMG-Co-enzyme-A-reductase inhibitors without CK-elevation?
Journal: Atherosclerosis 20000301
Title: Lovastatin inhibits G1/S transition of normal human B-lymphocytes independent of apoptosis.
Journal: Experimental cell research 19991010
Title: Lovastatin augments sulindac-induced apoptosis in colon cancer cells and potentiates chemopreventive effects of sulindac.
Journal: Gastroenterology 19991001
Title: Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 19990801
Title: Effect of lipid-lowering strategies on tubular cell biology.
Journal: Kidney international. Supplement 19990701
Title: Apoptosis and cell-cycle arrest in human and murine tumor cells are initiated by isoprenoids.
Journal: The Journal of nutrition 19990401
Title: Two different types of exercise-induced muscle pain without myopathy and CK-elevation during HMG-Co-enzyme-A-reductase inhibitor treatment.
Journal: Atherosclerosis 19990401
Title: Polymyalgia, hypersensitivity pneumonitis and other reactions in patients receiving HMG-CoA reductase inhibitors: a report of ten cases.
Journal: Chest 19990301
Title: Lovastatin-induced apoptosis of human medulloblastoma cell lines in vitro.
Journal: Journal of neuro-oncology 19990301
Title: Statins and peripheral neuropathy.
Journal: European journal of clinical pharmacology 19990101
Title: Lovastatin inhibits mesangial cell proliferation via p27Kip1.
Journal: Journal of the American Society of Nephrology : JASN 19981201
Title: The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway.
Journal: Cancer research 19981201
Title: The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.
Journal: The Journal of clinical investigation 19980901
Title: Peripheral neuropathy and lipid-lowering therapy.
Journal: Southern medical journal 19980701
Title: Insulin-like growth factor-I promotes multidrug resistance in MCLM colon cancer cells.
Journal: Journal of cellular physiology 19980501
Title: Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19980401
Title: Aggressive lipid lowering in postcoronary angioplasty patients with elevated cholesterol (the Lovastatin Restenosis Trial).
Journal: The American journal of cardiology 19980301
Title: Dose- and time-dependent hypocholesterolemic effect of oyster mushroom (Pleurotus ostreatus) in rats.
Journal: Nutrition (Burbank, Los Angeles County, Calif.) 19980301
Title: Failure of antioxidant therapy to attenuate interstitial disease in rats with reversible nephrotic syndrome.
Journal: Journal of the American Society of Nephrology : JASN 19980201
Title: Lovastatin induces apoptosis by inhibiting mitotic and post-mitotic events in cultured mesangial cells.
Journal: Biochimica et biophysica acta 19971030
Title: (1 alpha, 2 beta, 3 beta, 4 alpha)-1,2-bis[N-propyl-N-(4-phenoxybenzyl) amino]carbonyl]cyclobutane-3,4-dicarboxylic acid (A-87049): a novel potent squalene synthase inhibitor.
Journal: Journal of medicinal chemistry 19970704
Title: Comparison of bezafibrate and simvastatin in the treatment of dyslipidaemia in patients with NIDDM.
Journal: Diabetic medicine : a journal of the British Diabetic Association 19970701
Title: Rhabdomyolysis, acute renal failure and hepatopathy induced by lovastatin monotherapy.
Journal: Japanese heart journal 19970701
Title: Rationale and design features of a clinical trial examining the effects of cholesterol lowering and angiotensin-converting enzyme inhibition on coronary atherosclerosis: Simvastatin/Enalapril Coronary Atherosclerosis Trial (SCAT). SCAT Investigators.
Journal: The Canadian journal of cardiology 19970601
Title: [Myopathy caused by inhibitors of hydroxymethylglutaryl-coenzyme A reductase].
Journal: Revista de neurologia 19970601
Title: Polymyositis associated with simvastatin.
Journal: Lancet (London, England) 19970531
Title: Rhabdomyolysis associated with simvastatin-gemfibrozil therapy.
Journal: Southern medical journal 19970501
Title: Geranylgeraniol potentiates lovastatin inhibition of oncogenic H-Ras processing and signaling while preventing cytotoxicity.
Journal: Oncogene 19970123
Title: Myositis and rhabdomyolysis associated with concurrent use of simvastatin and nefazodone.
Journal: JAMA 19970101
Title: A head-to-head comparison of the cost effectiveness of HMG-CoA reductase inhibitors and fibrates in different types of primary hyperlipidemia.
Journal: Cardiovascular drugs and therapy 19970101
Title: Simvastatin-induced myopathy in a patient treated for hypercholesterolemia. Morphological aspects.
Journal: Polish journal of pathology : official journal of the Polish Society of Pathologists 19970101
Title: Human multidrug-resistant (MRP,p190) myeloid leukemia HL-60/ADR cells in vitro: resistance to the mevalonate pathway inhibitor lovastatin.
Journal: Neoplasma 19970101
Title: Acute on chronic renal failure induced by simvastatin.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19961101
Title: Lovastatin-associated dermatomyositis.
Journal: Postgraduate medical journal 19961101
Title: [Hepatitis due to lovastatin].
Journal: Medicina clinica 19961026
Title: Myoglobinuric renal failure due to long-standing lovastatin therapy in a patient with pre-existing chronic renal insufficiency.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19961001
Title: Effects of HMG-CoA reductase inhibitors on growth and differentiation of cultured rat skeletal muscle cells.
Journal: Biochimica et biophysica acta 19960412
Title: HMG-CoA reductase inhibitor-induced impotence.
Journal: The Annals of pharmacotherapy 19960201
Title: Fluvastatin in combination with other lipid-lowering agents.
Journal: British journal of clinical practice. Supplement 19960101
Title: [Terminal myoglobinuric renal failure in lovastatin therapy with pre-existing chronic renal insufficiency].
Journal: Wiener klinische Wochenschrift 19960101
Title: Lovastatin and peripheral neuropathy.
Journal: American heart journal 19951201
Title: Enalapril and peripheral neuropathy.
Journal: Journal of the American Geriatrics Society 19951001
Title: Currently available hypolipidaemic drugs and future therapeutic developments.
Journal: Bailliere's clinical endocrinology and metabolism 19951001
Title: Lovastatin-induced myopathy in a hypothyroid patient.
Journal: The Journal of family practice 19950901
Title: Lovastatin-induced hemolytic anemia: not a class-specific reaction.
Journal: The American journal of medicine 19950901
Title: Depression-induced absenteeism in relation to antihyperlipidemic treatment: a study using GAZEL cohort data.
Journal: Epidemiology (Cambridge, Mass.) 19950501
Title: Peripheral neuropathy associated with simvastatin.
Journal: Journal of neurology, neurosurgery, and psychiatry 19950501
Title: [Lovastatin-induced acute cholestatic hepatitis].
Journal: Deutsche medizinische Wochenschrift (1946) 19950224
Title: In vivo enhanced antitumor activity of carmustine [N,N'-bis(2-chloroethyl)-N-nitrosourea] by simvastatin.
Journal: Cancer research 19950201
Title: Fluvastatin in combination with other lipid-lowering agents.
Journal: British journal of clinical practice. Supplement 19941201
Title: Expanded Clinical Evaluation of Lovastatin (EXCEL) study results: two-year efficacy and safety follow-up.
Journal: The American journal of cardiology 19941001
Title: Synthesis and biological activity of bile acid-derived HMG-CoA reductase inhibitors. The role of 21-methyl in recognition of HMG-CoA reductase and the ileal bile acid transport system.
Journal: Journal of medicinal chemistry 19940930
Title: Cytotoxicity of simvastatin to pancreatic adenocarcinoma cells containing mutant ras gene.
Journal: Japanese journal of cancer research : Gann 19940601
Title: HMG-CoA reductase inhibitor therapy and peripheral neuropathy.
Journal: Annals of internal medicine 19940601
Title: Sleep disturbance and appetite loss after lovastatin.
Journal: Lancet (London, England) 19940416
Title: Isoprenoid biosynthesis in rat liver mitochondria. Studies on farnesyl pyrophosphate synthase and trans-prenyltransferase.
Journal: The Journal of biological chemistry 19940225
Title: Simvastatin-associated dermatomyositis.
Journal: British journal of rheumatology 19940201
Title: [Porphyria cutanea tarda induced by HMG CoA reductase inhibitors: simvastatin, pravastatin].
Journal: Annales de dermatologie et de venereologie 19940101
Title: Effect of simvastatin treatment on plasma apolipoproteins and hepatic apolipoprotein mRNA levels in the genetically hypercholesterolemic rat (RICO).
Journal: Life sciences 19940101
Title: Inhibitors of cholesterol biosynthesis. 1. 3,5-Dihydroxy-7-(N-imidazolyl)-6-heptenoates and -heptanoates, a novel series of HMG-CoA reductase inhibitors.
Journal: Journal of medicinal chemistry 19931112
Title: Inhibitors of cholesterol biosynthesis. 2. 3,5-Dihydroxy-7-(N-pyrrolyl)-6-heptenoates, a novel series of HMG-CoA reductase inhibitors.
Journal: Journal of medicinal chemistry 19931112
Title: HMG-CoA reductase inhibitors: design, synthesis, and biological activity of tetrahydroindazole-substituted 3,5-dihydroxy-6-heptenoic acid sodium salts.
Journal: Journal of medicinal chemistry 19931112
Title: Unrecognized adverse drug reactions.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 19931101
Title: Lovastatin-associated sleep and mood disturbances.
Journal: The American journal of medicine 19931101
Title: Simvastatin inhibits PDGF-induced DNA synthesis in human glomerular mesangial cells.
Journal: Kidney international 19930901
Title: Rhabdomyolysis and renal failure secondary to combination therapy of hyperlipidemia with lovastatin and gemfibozil.
Journal: Connecticut medicine 19930901
Title: Experimental lovastatin myopathy.
Journal: Journal of neuropathology and experimental neurology 19930901
Title: Selective inhibition of mammalian lanosterol 14 alpha-demethylase: a possible strategy for cholesterol lowering.
Journal: Journal of medicinal chemistry 19930723
Title: [Psychiatric disorders with use of simvastatin].
Journal: Nederlands tijdschrift voor geneeskunde 19930626
Title: Pravastatin inhibited the cholesterol synthesis in human hepatoma cell line Hep G2 less than simvastatin and lovastatin, which is reflected in the upregulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and squalene synthase.
Journal: Biochemical pharmacology 19930609
Title: Efficacy and tolerability of lovastatin in 3390 women with moderate hypercholesterolemia.
Journal: Annals of internal medicine 19930601
Title: Lovastatin 5-year safety and efficacy study. Lovastatin Study Groups I through IV.
Journal: Archives of internal medicine 19930510
Title: The effect of the HMG-CoA reductase inhibitor simvastatin and of cholestyramine on hepatic apolipoprotein mRNA levels in the rat.
Journal: Biochimica et biophysica acta 19930317
Title: Lovastatin and cholestasis.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 19930201
Title: Depressive symptoms and cholesterol-lowering drugs.
Journal: Lancet (London, England) 19930109
Title: Influence of specific mutations at the LDL-receptor gene locus on the response to simvastatin therapy in Afrikaner patients with heterozygous familial hypercholesterolaemia.
Journal: Atherosclerosis 19930104
Title: Effects of anti-hyperlipidaemic agent or dietary protein restriction on progressive renal deterioration in adriamycin-induced nephropathy in rats.
Journal: International urology and nephrology 19930101
Title: RG 12561 (dalvastatin): a novel synthetic inhibitor of HMG-CoA reductase and cholesterol-lowering agent.
Journal: Pharmacology 19930101
Title: 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 9. The synthesis and biological evaluation of novel simvastatin analogs.
Journal: Journal of medicinal chemistry 19921016
Title: Synthesis and biological evaluation of dihydroeptastatin, a novel inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Journal: Journal of medicinal chemistry 19920904
Title: [Toxic drug-induced hyposmia with lovastatin].
Journal: Laryngo- rhino- otologie 19920901
Title: Possible mechanism and treatment of o,p'DDD-induced hypercholesterolaemia.
Journal: The Quarterly journal of medicine 19920901
Title: Regulation of HMG-CoA reductase, apoprotein-B and LDL receptor gene expression by the hypocholesterolemic drugs simvastatin and ciprofibrate in Hep G2, human and rat hepatocytes.
Journal: Biochimica et biophysica acta 19920709
Title: Gemfibrozil-lovastatin therapy for primary hyperlipoproteinemias.
Journal: The American journal of cardiology 19920701
Title: Myopathy associated with HMG-CoA reductase inhibitors (HMGRIs) and cyclosporin A: evaluation in a rat model.
Journal: European heart journal 19920701
Title: Inhibitors of cholesterol biosynthesis. 6. trans-6-[2-(2-N-heteroaryl-3,5-disubstituted- pyrazol-4-yl)ethyl/ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-ones.
Journal: Journal of medicinal chemistry 19920529
Title: Lovastatin-induced hepatitis.
Journal: Israel journal of medical sciences 19920201
Title: Transcriptional derepression of the murine Cyp1a-1 gene by mevinolin.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19920106
Title: Hepatotoxicity of hydroxy-methyl-glutaryl-coenzyme A reductase inhibitors.
Journal: Minerva gastroenterologica e dietologica 19920101
Title: Lovastatin/gemfibrozil myopathy: a clinical, histochemical, and ultrastructural study.
Journal: European neurology 19920101
Title: Lack of hypotension with lovastatin and pravastatin.
Journal: Lancet (London, England) 19911123
Title: Synthesis and biological activity of new HMG-CoA reductase inhibitors. 3. Lactones of 6-phenoxy-3,5-dihydroxyhexanoic acids.
Journal: Journal of medicinal chemistry 19911001
Title: Gemfibrozil-induced myopathy.
Journal: Archives of internal medicine 19910901
Title: Phosphorus-containing inhibitors of HMG-CoA reductase. 2. Synthesis and biological activities of a series of substituted pyridines containing a hydroxyphosphinyl moiety.
Journal: Journal of medicinal chemistry 19910901
Title: 3-Hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors. 7. Modification of the hexahydronaphthalene moiety of simvastatin: 5-oxygenated and 5-oxa derivatives.
Journal: Journal of medicinal chemistry 19910801
Title: Cholesterol-lowering agent myopathy (CLAM).
Journal: Neurology 19910701
Title: HMG-CoA reductase inhibitor-induced myopathy in the rat: cyclosporine A interaction and mechanism studies.
Journal: The Journal of pharmacology and experimental therapeutics 19910601
Title: [Cholestatic jaundice during lovastatin medication].
Journal: Deutsche medizinische Wochenschrift (1946) 19910510
Title: Effect of simvastatin (MK-733) on plasma triacylglycerol levels in rats.
Journal: Biochemical pharmacology 19910415
Title: Simvastatin and proteinuria.
Journal: Lancet (London, England) 19910406
Title: Acute cholestatic hepatitis during simvastatin administration.
Journal: Recenti progressi in medicina 19910401
Title: Expanded Clinical Evaluation of Lovastatin (EXCEL) study results. I. Efficacy in modifying plasma lipoproteins and adverse event profile in 8245 patients with moderate hypercholesterolemia.
Journal: Archives of internal medicine 19910101
Title: Inhibitors of cholesterol biosynthesis. 4. trans-6-[2-(substituted-quinolinyl)ethenyl/ethyl]tetrahydro-4-hydroxy-2 H-pyran-2-ones, a novel series of HMG-CoA reductase inhibitors.
Journal: Journal of medicinal chemistry 19910101
Title: Rhabdomyolysis with simvastatin use.
Journal: Nephron 19910101
Title: Proteinuria as complication of simvastatin treatment.
Journal: Lancet (London, England) 19901208
Title: Rhabdomyolysis secondary to lovastatin therapy.
Journal: Clinical chemistry 19901201
Title: Synthesis, biological profile, and quantitative structure-activity relationship of a series of novel 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors.
Journal: Journal of medicinal chemistry 19901101
Title: Lovastatin decreases coenzyme Q levels in humans.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19901101
Title: Inhibitors of hydroxymethylglutaryl coenzyme A reductase for treating hypercholesterolaemia.
Journal: BMJ (Clinical research ed.) 19900929
Title: Myopathy and rhabdomyolysis associated with lovastatin-gemfibrozil combination therapy.
Journal: JAMA 19900704
Title: Cholestatic jaundice associated with lovastatin (Mevacor) therapy.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 19900415
Title: Purification and regulation of mevalonate kinase from rat liver.
Journal: The Journal of biological chemistry 19900205
Title: Rhabdomyolysis and acute renal failure induced by combination lovastatin and gemfibrozil therapy.
Journal: Annals of internal medicine 19900201
Title: Synthesis and biological activity of new HMG-CoA reductase inhibitors. 2. Derivatives of 7-(1H-pyrrol-3-yl)-substituted-3,5-dihydroxyhept-6(E)-enoic (-heptanoic) acids.
Journal: Journal of medicinal chemistry 19900101
Title: Inhibitors of cholesterol biosynthesis. 2. 1,3,5-trisubstituted [2-(tetrahydro-4-hydroxy-2-oxopyran-6-yl)ethyl]pyrazoles.
Journal: Journal of medicinal chemistry 19900101
Title: Synthesis and biological activity of new HMG-CoA reductase inhibitors. 1. Lactones of pyridine- and pyrimidine-substituted 3,5-dihydroxy-6-heptenoic (-heptanoic) acids.
Journal: Journal of medicinal chemistry 19900101
Title: Lovastatin, isoprenes, and myopathy.
Journal: Lancet (London, England) 19891104
Title: Plasma mevalonate response in lovastatin-related myopathy.
Journal: Lancet (London, England) 19891104
Title: Transient symptomatic hypotension in patients on simvastatin.
Journal: Lancet (London, England) 19890930
Title: Treatment of heterozygous familial hypercholesterolemia with lipid-lowering drugs.
Journal: Arteriosclerosis (Dallas, Tex.) 19890101
Title: Efficacy and long-term adverse effect pattern of lovastatin.
Journal: The American journal of cardiology 19881111
Title: Rhabdomyolysis and renal injury with lovastatin use. Report of two cases in cardiac transplant recipients.
Journal: JAMA 19880708
Title: Myolysis and acute renal failure in a heart-transplant recipient receiving lovastatin.
Journal: The New England journal of medicine 19880107
Title: HMG CoA reductase inhibitors. Current clinical experience.
Journal: Drugs 19880101
Title: Total synthesis and biological evaluation of structural analogues of compactin and dihydromevinolin.
Journal: Journal of medicinal chemistry 19871001
Title: 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 4. Side chain ester derivatives of mevinolin.
Journal: Journal of medicinal chemistry 19860501
Title: Activation of rat liver microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase by NADPH. Effects of dietary treatments.
Journal: The Journal of biological chemistry 19851015
Title: Sources of extramitochondrial corticoidogenic cholesterol in the adrenal cortex.
Journal: Japanese journal of pharmacology 19850601
Title: Compactin (ML-236B) and related compounds as potential cholesterol-lowering agents that inhibit HMG-CoA reductase.
Journal: Journal of medicinal chemistry 19850401
Title: Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19800701
Title: Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity.
Journal: FEBS letters 19761231
