Title: Insights into the inhibition of the p90 ribosomal S6 kinase (RSK) by the flavonol glycoside SL0101 from the 1.5 Å crystal structure of the N-terminal domain of RSK2 with bound inhibitor.
Journal: Biochemistry 20120821
Title: Spectaflavoside A, a new potent iron chelating dimeric flavonol glycoside from the rhizomes of Zingiber spectabile Griff.
Journal: Bioorganic & medicinal chemistry letters 20120601
Title: Analogs of the RSK inhibitor SL0101: optimization of in vitro biological stability.
Journal: Bioorganic & medicinal chemistry letters 20120501
Title: Differential mTOR and ERK pathway utilization by effector CD4 T cells suggests combinatorial drug therapy of arthritis.
Journal: Clinical immunology (Orlando, Fla.) 20120201
Title: SHAFTS: a hybrid approach for 3D molecular similarity calculation. 2. Prospective case study in the discovery of diverse p90 ribosomal S6 protein kinase 2 inhibitors to suppress cell migration.
Journal: Journal of medicinal chemistry 20110526
Title: Differential regulation of NHE1 phosphorylation and glucose uptake by inhibitors of the ERK pathway and p90RSK in 3T3-L1 adipocytes.
Journal: Cellular signalling 20091201
Title: Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells.
Journal: Breast cancer research : BCR 20080101
Title: The selectivity of protein kinase inhibitors: a further update.
Journal: The Biochemical journal 20071215
Title: Structural basis for the activity of the RSK-specific inhibitor, SL0101.
Journal: Bioorganic & medicinal chemistry 20070715
Title: De novo asymmetric syntheses of SL0101 and its analogues via a palladium-catalyzed glycosylation.
Journal: Organic letters 20061026
Title: Influence of rhamnose substituents on the potency of SL0101, an inhibitor of the Ser/Thr kinase, RSK.
Journal: Bioorganic & medicinal chemistry 20060901
Title: Homology model of RSK2 N-terminal kinase domain, structure-based identification of novel RSK2 inhibitors, and preliminary common pharmacophore.
Journal: Bioorganic & medicinal chemistry 20060901
Title: Sesquiterpenes and flavonol glycosides from Zingiber aromaticum and their CYP3A4 and CYP2D6 inhibitory activities.
Journal: Journal of natural products 20040701
Title: Smith JA, et al. Identification of the first specific inhibitor of p90 ribosomal S6 kinase (RSK) reveals an unexpected role for RSK in cancer cell proliferation. Cancer Res. 2005 Feb 1;65(3):1027-34.
Title: Yu Li, et al. The Affinity of RSK for Cylitol Analogues of SL0101 Is Critically Dependent on the B-ring C-4'-hydroxy. Chem Commun (Camb). 2020 Mar 10;56(20):3058-3060.
