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68-89-3,MFCD00020783
Catalog No.:AA006FVR

68-89-3 | Dipyrone

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25g
≥98%
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$69.00   $48.00
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50g
≥98%
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA006FVR
Chemical Name:
Dipyrone
CAS Number:
68-89-3
Molecular Formula:
C13H16N3NaO4S
Molecular Weight:
333.3386
MDL Number:
MFCD00020783
SMILES:
CN(c1c(C)n(n(c1=O)c1ccccc1)C)CS(=O)(=O)[O-].[Na+]
Properties
Properties
 
Form:
Solid  
MP:
212-215°C  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
552  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
6  
Rotatable Bond Count:
4  

Literature

Title: Synergistic effect of the L-tryptophan and kynurenic acid with dipyrone or paracetamol in mice.

Journal: Chemico-biological interactions 20130925

Title: High-performance liquid chromatographic assay for metamizol metabolites in rat plasma: application to pharmacokinetic studies.

Journal: Journal of pharmaceutical and biomedical analysis 20121201

Title: Factors associated with intolerance after refeeding in mild acute pancreatitis.

Journal: Pancreas 20121101

Title: Involvement of PGE2 and RANTES in Staphylococcus aureus-induced fever in rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20121101

Title: Hypernociception and wound healing after application of cyanoacrylate ester as a tissue adhesive in rats.

Journal: Oral surgery, oral medicine, oral pathology and oral radiology 20121101

Title: Evaluation of the endogenous cannabinoid system in mediating the behavioral effects of dipyrone (metamizol) in mice.

Journal: Behavioural pharmacology 20121001

Title: Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms. part II: furoxan derivatives.

Journal: Journal of medicinal chemistry 20120913

Title: Dexamethasone versus ondansetron in combination with dexamethasone for the prophylaxis of postoperative vomiting in pediatric outpatients: a double-blind, randomized, placebo-controlled clinical trial.

Journal: Paediatric anaesthesia 20120901

Title: Antinociceptive and anti-inflammatory activities of crude methanolic extract of red alga Bryothamnion triquetrum.

Journal: Marine drugs 20120901

Title: Importance of MS selectivity and chromatographic separation in LC-MS/MS-based methods when investigating pharmaceutical metabolites in water. Dipyrone as a case of study.

Journal: Journal of mass spectrometry : JMS 20120801

Title: The effect of paracetamol, metamizole sodium and ibuprofen on postoperative hemorrhage following pediatric tonsillectomy.

Journal: International journal of pediatric otorhinolaryngology 20120701

Title: Oral administration of an anti-inflammatory does not compromise the efficacy of intra-testicular injection of zinc gluconate as a contraceptive for dogs.

Journal: Animal reproduction science 20120601

Title: IgE-mediated metamizol allergy and the usefulness of the cellular allergen stimulation test.

Journal: European annals of allergy and clinical immunology 20120601

Title: Dipyrone attenuates acute sickness response to lipopolysaccharide in mice.

Journal: Neuroscience letters 20120510

Title: Effect of dipyrone and thalidomide alone and in combination on STZ-induced diabetic neuropathic pain.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120501

Title: Metamizol, a non-opioid analgesic, acts via endocannabinoids in the PAG-RVM axis during inflammation in rats.

Journal: European journal of pain (London, England) 20120501

Title: [Pharmacokinetics interaction between methadone and metamizole: study of 53 cases].

Journal: Medicina clinica 20120428

Title: Near-infrared spectrometric determination of dipyrone in closed ampoules.

Journal: Talanta 20120415

Title: The role of inflammation and COX-derived prostanoids in the effects of bradykinin on isolated rat aorta and urinary bladder.

Journal: Inflammation 20120401

Title: [Lupus, Graves' disease, and vasculitis: a case report].

Journal: Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20120301

Title: [Peripheral acting mediators pain and analgesia potentiate the central analgesic action of fentanyl and dipyrone].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20120301

Title: Analgesic effectiveness of dipyrone (metamizol) for postoperative pain after herniorrhaphy: a randomized, double-blind, dose-response study.

Journal: Pain practice : the official journal of World Institute of Pain 20120201

Title: Ibuprofen or diclofenac is associated with more severe acute kidney injury in nephropathia epidemica.

Journal: Scandinavian journal of urology and nephrology 20120201

Title: Efficacy and tolerability of combined dipyrone, isometheptene and caffeine in the treatment of mild-to-moderate primary headache episodes.

Journal: Expert review of neurotherapeutics 20120201

Title: Determination of dipyrone in pharmaceutical preparations based on the chemiluminescent reaction of the quinolinic hydrazide-H2O2-vanadium(IV) system and flow-injection analysis.

Journal: Luminescence : the journal of biological and chemical luminescence 20120101

Title: Novel bioactive metabolites of dipyrone (metamizol).

Journal: Bioorganic & medicinal chemistry 20120101

Title: [Continuous propofol perfusion in critically ill children].

Journal: Medicina intensiva 20120101

Title: Difficulty in diagnosing oral paracoccidioidomycosis after topical nystatin usage.

Journal: General dentistry 20120101

Title: [Metamizole in postoperative pain management].

Journal: Nederlands tijdschrift voor geneeskunde 20120101

Title: A randomized, double-blind, controlled trial on non-opioid analgesics and opioid consumption for postoperative pain relief after laparoscopic cholecystectomy.

Journal: Acta anaesthesiologica Belgica 20120101

Title: Postoperative pain management at Tirana university hospital center -Mother Teresa-, Tirana, Albania.

Journal: Journal of biological regulators and homeostatic agents 20120101

Title: Anaphylaxis due to sulpiride and sensitization to metamizole.

Journal: Journal of investigational allergology & clinical immunology 20120101

Title: Intrapleural analgesia after endoscopic thoracic sympathectomy.

Journal: Acta cirurgica brasileira 20111201

Title: Dipyrone inhibits neuronal cell death and diminishes hypoxic/ischemic brain injury.

Journal: Neurosurgery 20111001

Title: Antinociceptive and anti-inflammatory activities of nicotinamide and its isomers in different experimental models.

Journal: Pharmacology, biochemistry, and behavior 20111001

Title: Cobalt phthalocyanine as a biomimetic catalyst in the amperometric quantification of dipyrone using FIA.

Journal: Talanta 20110930

Title: [Pupillary block acute glaucoma due to acrylic intraocular lens posterior dislocation after Nd:YAG capsulotomy].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20110901

Title: Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms.

Journal: Journal of medicinal chemistry 20110825

Title: Analgesic and anti-inflammatory activities of salicylaldehyde 2-chlorobenzoyl hydrazone (H(2)LASSBio-466), salicylaldehyde 4-chlorobenzoyl hydrazone (H(2)LASSBio-1064) and their zinc(II) complexes.

Journal: Molecules (Basel, Switzerland) 20110815

Title: Over-expression of the LTC4 synthase gene in mice reproduces human aspirin-induced asthma.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20110801

Title: The use of different doses of metamizol for post-operative analgesia in dogs.

Journal: Veterinary anaesthesia and analgesia 20110701

Title: Myometrial response to neurotropic and musculotropic spasmolytic drugs in an extracorporeal perfusion model of swine uteri.

Journal: Reproductive biomedicine online 20110701

Title: [Synergistic combination therapy in osteoporosis. Strategies against painful bone loss].

Journal: MMW Fortschritte der Medizin 20110512

Title: Mechanisms involved in the antinociceptive effects of 7-hydroxycoumarin.

Journal: Journal of natural products 20110425

Title: [Postoperative pain management after ambulatory surgery. A survey of anaesthesiologists].

Journal: Schmerz (Berlin, Germany) 20110401

Title: [Medical management of acute renal colic - there is more than hydration and Buscopan®...].

Journal: Praxis 20110302

Title: Subchronic effects of dipyrone on the fish species Rhamdia quelen.

Journal: Ecotoxicology and environmental safety 20110301

Title: The antipyretic effect of dipyrone is unrelated to inhibition of PGE(2) synthesis in the hypothalamus.

Journal: British journal of pharmacology 20110301

Title: Efficacy of intravenous paracetamol compared to dipyrone and parecoxib for postoperative pain management after minor-to-intermediate surgery: a randomised, double-blind trial.

Journal: European journal of anaesthesiology 20110201

Title: The role of metamizol induction for the detection of perfusion reversibility on thallium-201 myocardial perfusion scintigraphy.

Journal: Nuclear medicine communications 20110201

Title: [Estimation of postoperative pain after tonsillectomy in adults using QUIPS: an instrument to improve postoperative pain management].

Journal: Laryngo- rhino- otologie 20110201

Title: [17-year-old patient with neutropenia and fever during therapy with analgesics].

Journal: Deutsche medizinische Wochenschrift (1946) 20110201

Title: Comparison of dipyrone/propofol versus fentanyl/propofol anaesthesia during surgery in rabbits.

Journal: Laboratory animals 20110101

Title: Antipyretic effect of ibuprofen and dipyrone in febrile children.

Journal: Jornal de pediatria 20110101

Title: Standardized antipyretic treatment in stroke: a pilot study.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20110101

Title: Effective fever control in acute stroke: still wanted!

Journal: Cerebrovascular diseases (Basel, Switzerland) 20110101

Title: Metamizole is not as safe as we think or assume.

Journal: Turkish neurosurgery 20110101

Title: Opioid sensitivity of nucleus raphe magnus ater analgesia by nonsteroidal anti-inflammatory drugs.

Journal: Georgian medical news 20110101

Title: Acute kidney injury associated with metamizole sodium ingestion.

Journal: Renal failure 20110101

Title: Effect of Buscopan compositum on the motility of the duodenum, cecum and left ventral colon in healthy conscious horses.

Journal: Berliner und Munchener tierarztliche Wochenschrift 20110101

Title: Efficiency of postoperative pain management after gynecologic oncological surgeries with the use of morphine + acetaminophen + ketoprofen versus morphine + metamizol + ketoprofen.

Journal: European journal of gynaecological oncology 20110101

Title: Epidural and opioid analgesia following the Nuss procedure.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20110101

Title: N-acetyltransferase 2 polymorphisms and susceptibility to infant leukemia with maternal exposure to dipyrone during pregnancy.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20101201

Title: Population pharmacokinetic analysis of the active product of dipyrone.

Journal: International journal of clinical pharmacology and therapeutics 20101201

Title: [Chronic dizziness in a pain patient--pharmacogenomic identification of tramadol as cause].

Journal: Die Rehabilitation 20101201

Title: Assessment of early post-operative pain following septorhinoplasty.

Journal: The Journal of laryngology and otology 20101101

Title: Synthesis and biological evaluation of N-antipyrine-4-substituted amino-3-chloromaleimide derivatives.

Journal: European journal of medicinal chemistry 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: [Quality of over-the-counter medicines: a study with dipyrone brands commercialized in a drugstore in Cascavel city (Paraná, Brazil)].

Journal: Ciencia & saude coletiva 20101101

Title: Effect of metamizol on morphine pharmacokinetics and pharmacodynamics after acute and subchronic administration in arthritic rats.

Journal: European journal of pharmacology 20101025

Title: Antinociceptive effect of methanol extract of Capparis ovata in mice.

Journal: Pharmaceutical biology 20101001

Title: Primary dysmenorrhea among Mexican university students: prevalence, impact and treatment.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20100901

Title: [A non-abscess-forming inflammation of the corpora cavernosa in a diabetic patient - case report].

Journal: Aktuelle Urologie 20100901

Title: Immediate rhinoconjunctivitis induced by metamizole: an allergic reaction?

Journal: Allergy 20100801

Title: Graphite-epoxy electrodes modified with functionalised carbon nanotubes and chitosan for the rapid electrochemical determination of dipyrone.

Journal: Combinatorial chemistry & high throughput screening 20100801

Title: Investigation of the microbial degradation of phenazone-type drugs and their metabolites by natural biofilms derived from river water using liquid chromatography/tandem mass spectrometry (LC-MS/MS).

Journal: Water research 20100801

Title: Analgesic, anti-pyretic and DNA cleavage studies of novel pyrimidine derivatives of coumarin moiety.

Journal: European journal of medicinal chemistry 20100601

Title: [Antipyretic strategies for acute stroke: a nationwide survey among German stroke units].

Journal: Der Nervenarzt 20100601

Title: Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.

Journal: European journal of anaesthesiology 20100501

Title: [Urolithiasis].

Journal: MMW Fortschritte der Medizin 20100422

Title: Synergism between COX-3 inhibitors in two animal models of pain.

Journal: Inflammopharmacology 20100401

Title: Elevated urinary biopyrrin excretion and oxidative bilirubin metabolism during 24-hour ultramarathon running.

Journal: Rinsho byori. The Japanese journal of clinical pathology 20100401

Title: Transient renal insufficiency following dipyrone overdose.

Journal: Archives of disease in childhood 20100301

Title: Tolerance induced by non-opioid analgesic microinjections into rat's periaqueductal gray and nucleus raphe.

Journal: Georgian medical news 20100301

Title: Analgesic and antiinflammatory activity of Morinda citrifolia L. (Noni) fruit.

Journal: Phytotherapy research : PTR 20100101

Title: Postoperative and preincisional electrical nerve stimulation TENS reduce postoperative opioid requirement after major spinal surgery.

Journal: Journal of neurosurgical anesthesiology 20100101

Title: Effects of postoperative analgesia on acute phase response in thoracic surgery.

Journal: Medicinski arhiv 20100101

Title: Postoperative pain and respiratory function in patients treated with electroacupuncture following coronary surgery.

Journal: Neurosciences (Riyadh, Saudi Arabia) 20100101

Title: Individual variability of response and non-response to acetyl salicylic acid after cardiac surgery.

Journal: Platelets 20100101

Title: Single dose dipyrone for acute postoperative pain.

Journal: The Cochrane database of systematic reviews 20100101

Title: Update on the incidence of metamizole sodium-induced blood dyscrasias in Poland.

Journal: The Journal of international medical research 20100101

Title: Phenylpyrazolone derivatives inhibit gastric emptying in rats by a capsaicin-sensitive afferent pathway.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20091101

Title: Cardiovascular effects of dipyrone and propofol on hemodynamic function in rabbits.

Journal: American journal of veterinary research 20091101

Title: The effects of chronic administration of sumatriptan and dipyrone on serotonergic system in the rat brain: an immunohistochemical study.

Journal: Acta neurologica Scandinavica 20091001

Title: Drug/nutrition interaction in the developing brain: dipyrone enhances spreading depression in rats.

Journal: Experimental neurology 20091001

Title: Toponomics analysis of drug-induced changes in arachidonic acid-dependent signaling pathways during spinal nociceptive processing.

Journal: Journal of proteome research 20091001

Title: Synthesis and analgesic profile of conformationally constrained N-acylhydrazone analogues: discovery of novel N-arylideneamino quinazolin-4(3H)-one compounds derived from natural safrole.

Journal: Bioorganic & medicinal chemistry 20090915

Title: Sciatic injection injuries in adults: is dipyrone a foe to nerve?

Journal: Acta neurologica Belgica 20090901

Title: [Adverse events associated with tramadol and dipirona administration in a level III hospital].

Journal: Biomedica : revista del Instituto Nacional de Salud 20090901

Title: Effect of 5-trifluoromethyl-4,5-dihydro-1H-pyrazoles on chronic inflammatory pain model in rats.

Journal: European journal of pharmacology 20090815

Title: The effective duration of analgesia after intrathecal morphine in patients without additional opioid analgesia: a randomized double-blind multicentre study on orthopaedic patients.

Journal: European journal of anaesthesiology 20090801

Title: Immunoglobulin E-mediated immediate allergic reactions to dipyrone: value of basophil activation test in the identification of patients.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20090801

Title: Analgesic efficacy of lysine clonixinate, paracetamol and dipyrone in lower third molar extraction: a randomized controlled trial.

Journal: Medicina oral, patologia oral y cirugia bucal 20090801

Title: Paracetamol versus metamizol in the treatment of postoperative pain after breast surgery: a randomized, controlled trial.

Journal: European journal of anaesthesiology 20090801

Title: [Influence of acupuncture on postoperative pain, nausea and vomiting after visceral surgery : a prospective, randomized comparative study of metamizole and standard treatment].

Journal: Schmerz (Berlin, Germany) 20090801

Title: Necrotising fasciitis caused by adulterated traditional Asian medicine: a case report.

Journal: Journal of orthopaedic surgery (Hong Kong) 20090801

Title: Can metamizol play a role in nuclear medicine practice?

Journal: European journal of nuclear medicine and molecular imaging 20090701

Title: Lack of effect of naltrindole on the spinal synergism of morphine and non-steroidal anti-inflammatory drugs (NSAIDS).

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20090601

Title: Characterization and pharmacological evaluation of febrile response on zymosan-induced arthritis in rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090501

Title: [Early results of surgical treatment of haemorrhoids at use of harmonic scalpel].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20090501

Title: Quantification of 4-methylaminoantipyrine, the active metabolite of dipyrone, in human plasma.

Journal: Bioanalysis 20090501

Title: D-propoxyphene and dipyrone co-administration produces greater antinociception and fewer adverse effects than single treatments in rats.

Journal: European journal of pharmacology 20090401

Title: [Agranulocytosis from metamizole: a potential problem for the British population].

Journal: Revista clinica espanola 20090401

Title: Dipyrone use during pregnancy and adverse perinatal events.

Journal: Archives of gynecology and obstetrics 20090301

Title: Dipyrone increases the blood flow of arterial dorsal skin flaps: are prospective studies always properly designed?

Journal: Aesthetic plastic surgery 20090301

Title: Determination of tramadol, metamizole, ropivacaine, and bupivacaine in analgesic mixture samples by HPLC with DAD detection.

Journal: Journal of chromatographic science 20090301

Title: Tolerance to non-opioid analgesics in PAG involves unresponsiveness of medullary pain-modulating neurons in male rats.

Journal: The European journal of neuroscience 20090301

Title: [Evaluation of the analgesic effects of the lumiracoxib compared with placebo in the 24 first postoperative hours].

Journal: Revista do Colegio Brasileiro de Cirurgioes 20090201

Title: Cooling therapy for acute stroke.

Journal: The Cochrane database of systematic reviews 20090121

Title: Nociceptive behavior induced by mustard oil injection into the temporomandibular joint is blocked by a peripheral non-opioid analgesic and a central opioid analgesic.

Journal: Pharmacology, biochemistry, and behavior 20090101

Title: Drug enhancement of myocardial tracer uptake during myocardial perfusion imaging.

Journal: European journal of nuclear medicine and molecular imaging 20090101

Title: Synthesis and pharmacological evaluation of N-(dimethylamino)ethyl derivatives of benzo- and pyridopyridazinones.

Journal: Archiv der Pharmazie 20090101

Title: The effect of nitric oxide synthase inhibitors on the development of analgesic tolerance to dipyrone in mice.

Journal: The International journal of neuroscience 20090101

Title: [Comparison of sublingual ketorolac vs. IV metamizole in the management of pain after same-day surgery].

Journal: Cirugia y cirujanos 20090101

Title: [Scorpionism caused by Tityus pusillus Pocock, 1893 (Scorpiones; Buthidae) in State of Pernambuco].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20090101

Title: Advise against metamizole.

Journal: Deutsches Arzteblatt international 20090101

Title: [Study of the ocular findings in Stevens-Johnson syndrome patients from a tertiary ophthalmologic center].

Journal: Arquivos brasileiros de oftalmologia 20090101

Title: [Safety of metamizole and paracetamol for acute pain treatment].

Journal: Anestezjologia intensywna terapia 20090101

Title: [Comparison of the analgesic effect between 90 mg etoricoxib and dipyrone after exeresis of primary pterygium with conjunctival autograft].

Journal: Arquivos brasileiros de oftalmologia 20090101

Title: Influence of oxcarbazepine on the antinociceptive action of morphine and metamizole in mice.

Journal: Acta poloniae pharmaceutica 20090101

Title: [Management of anxiety associated with oral surgery].

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20090101

Title: Antinociceptive action of 4-methyl-5-trifluoromethyl-5-hydroxy-4, 5-dihydro-1H-pyrazole methyl ester in models of inflammatory pain in mice.

Journal: Life sciences 20081121

Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Journal: Journal of medicinal chemistry 20081113

Title: The antinociceptive efficacy of morphine, metamizol, or their combination in an experimental rat model with different levels of inflammatory pain.

Journal: Pharmacology, biochemistry, and behavior 20081101

Title: [Leeches, phytotherapy and physiotherapy in osteo-arthrosis of the knee--a geriatric case study].

Journal: Forschende Komplementarmedizin (2006) 20081001

Title: Synthesis of new 1-phenyl-3-{4-[(2E)-3-phenylprop-2-enoyl]phenyl}-thiourea and urea derivatives with anti-nociceptive activity.

Journal: Bioorganic & medicinal chemistry 20080915

Title: Dipyrone increases the blood flow of arterial dorsal skin flaps.

Journal: Aesthetic plastic surgery 20080901

Title: Biphasic elevation of bilirubin oxidation during myocardial ischemia reperfusion.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20080901

Title: 99mTc sestamibi myocardial perfusion scintigraphy with the novel use of metamizol for the detection of perfusion reversibility.

Journal: European journal of nuclear medicine and molecular imaging 20080801

Title: Design and microwave-assisted synthesis of 5-trifluoromethyl-4,5-dihydro-1H-pyrazoles: novel agents with analgesic and anti-inflammatory properties.

Journal: European journal of medicinal chemistry 20080601

Title: Femoral nerve blockade administered preclinically for pain relief in severe knee trauma is more feasible and effective than intravenous metamizole: a randomized controlled trial.

Journal: The Journal of trauma 20080601

Title: Lysine clonixinate versus dipyrone (metamizole) for the acute treatment of severe migraine attacks: a single-blind, randomized study.

Journal: Arquivos de neuro-psiquiatria 20080601

Title: [Intrauterine closure of the ductus arteriosus probably associated with the taking of metamizole during the third trimester].

Journal: Anales de pediatria (Barcelona, Spain : 2003) 20080601

Title: Systemic effects of isolated brain injury: an experimental animal study.

Journal: Neurological research 20080601

Title: Photodegradation study of three dipyrone metabolites in various water systems: identification and toxicity of their photodegradation products.

Journal: Water research 20080501

Title: Study of non-opioid analgesics tolerance in young and adult rats.

Journal: Georgian medical news 20080501

Title: Life-threatening bite injury of the lower lip after use of metamizole.

Journal: Oral and maxillofacial surgery 20080501

Title: Occurrence, fate and assessment of polar metamizole (dipyrone) residues in hospital and municipal wastewater.

Journal: Chemosphere 20080401

Title: [Intrathecal morphine in orthopaedic surgery patients. Optimised dose in patients receiving dipyrone].

Journal: Der Anaesthesist 20080401

Title: Tepid sponging plus dipyrone versus dipyrone alone for reducing body temperature in febrile children.

Journal: Sao Paulo medical journal = Revista paulista de medicina 20080306

Title: Patient-controlled analgesia with lornoxicam vs. dipyrone for acute postoperative pain relief after septorhinoplasty: a prospective, randomized, double-blind, placebo-controlled study.

Journal: European journal of anaesthesiology 20080301

Title: Extralabel use of nonsteroidal anti-inflammatory drugs in cattle.

Journal: Journal of the American Veterinary Medical Association 20080301

Title: Efficacy of lornoxicam for acute postoperative pain relief after septoplasty: a comparison with diclofenac, ketoprofen, and dipyrone.

Journal: Journal of clinical anesthesia 20080301

Title: Different mechanisms underlie the analgesic actions of paracetamol and dipyrone in a rat model of inflammatory pain.

Journal: British journal of pharmacology 20080201

Title: [Chikungunya: fever and joint pains after vacation in a tropical area].

Journal: Deutsche medizinische Wochenschrift (1946) 20080201

Title: Pyrazolinone analgesics prevent the antiplatelet effect of aspirin and preserve human platelet thromboxane synthesis.

Journal: Journal of thrombosis and haemostasis : JTH 20080101

Title: Efficacy and tolerance of metamizole versus morphine for acute pancreatitis pain.

Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20080101

Title: Lipomatous metaplasia after severe and chronic cutaneous inflammation.

Journal: Dermatology (Basel, Switzerland) 20080101

Title: [Characterization of chronic pain and analgesic approaches among community-dwelling elderly].

Journal: Revista da Associacao Medica Brasileira (1992) 20080101

Title: Parecoxib versus dipyrone (metamizole) for postoperative pain relief after hysterectomy : a prospective, single-centre, randomized, double-blind trial.

Journal: Clinical drug investigation 20080101

Title: Singlet oxygen scavenging activity of non-steroidal anti-inflammatory drugs.

Journal: Redox report : communications in free radical research 20080101

Title: [Synergism of caffeine on antinociceptive effects of metamizole].

Journal: Cirugia y cirujanos 20080101

Title: [Estimated methods of predicting risk of analgetic interstitial renal disease].

Journal: Terapevticheskii arkhiv 20080101

Title: Antibiotic use in post-adenotonsillectomy morbidity: a randomized prospective study.

Journal: Brazilian journal of otorhinolaryngology 20080101

Title: [Is the assessment of serum creatinine reliable?].

Journal: Casopis lekaru ceskych 20080101

Title: Ketoprofen is superior to metamizole in relieving postoperative pain after head and neck tumor operation.

Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20080101

Title: Usefulness of intradermal test and patch test in the diagnosis of nonimmediate reactions to metamizol.

Journal: Allergy 20071201

Title: Flow-injection spectrophotometric determination of novalgin in pharmaceuticals using micellar medium.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20071201

Title: The effects of some nonsteroidal anti-inflammatory drugs on experimental induced gastric ulcers in rats.

Journal: Inflammopharmacology 20071201

Title: Adjunct dipyrone in association with oral morphine for cancer-related pain: the sooner the better.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20071101

Title: [Analysis of three metabolite residues of dipyrone in bovine muscle and pork muscle using high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20071101

Title: Are false-positive phencyclidine immunoassay instant-view multi-test results caused by overdose concentrations of Ibuprofen, metamizol, and dextromethorphan?

Journal: Therapeutic drug monitoring 20071001

Title: [Comparison of tramadol, tramadol-metamizol and tramadol-lornoxicam administered by intravenous PCA in management of postoperative pain].

Journal: Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology 20071001

Title: Selective induction of human hepatic cytochromes P450 2B6 and 3A4 by metamizole.

Journal: Clinical pharmacology and therapeutics 20070901

Title: Dipyrone elicits substantial inhibition of peripheral cyclooxygenases in humans: new insights into the pharmacology of an old analgesic.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070801

Title: Comparison of intravenous dexketoprofen and dipyrone in acute renal colic.

Journal: European journal of clinical pharmacology 20070801

Title: Bilirubin oxidation provoked by nitric oxide radicals predicts the progression of acute cardiac allograft rejection.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070801

Title: Effect of 4-aminoantipyrine on gastric compliance and liquid emptying in rats.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20070701

Title: Effect of cigarette smoking on serum hydrocodone levels in chronic pain patients.

Journal: The Journal of the Arkansas Medical Society 20070701

Title: Inhibition of cyclooxygenases by dipyrone.

Journal: British journal of pharmacology 20070601

Title: Multiple fixed drug eruption due to intradermal test with metamizole.

Journal: Allergy 20070601

Title: Urinary excretion of oxidative metabolites of bilirubin in subjects with Gilbert syndrome.

Journal: Journal of gastroenterology and hepatology 20070601

Title: Control of postoperative pain after awake craniotomy with local intradermal analgesia and metamizol.

Journal: The Israel Medical Association journal : IMAJ 20070501

Title: Dipyrone for acute primary headaches.

Journal: The Cochrane database of systematic reviews 20070418

Title: The local antinociceptive actions of nonsteroidal antiinflammatory drugs in the mouse radiant heat tail-flick test.

Journal: Anesthesia and analgesia 20070401

Title: [Cost-effectiveness analysis of patient-controlled analgesia compared to continuous elastomeric pump infusion of tramadol and metamizole].

Journal: Revista espanola de anestesiologia y reanimacion 20070401

Title: [Stress response under continuous infusion of remifentanil compared to bolus doses of fentanyl assessed by levels of cytokines, C-reactive protein, and cortisol during and after abdominal hysterectomy].

Journal: Revista espanola de anestesiologia y reanimacion 20070401

Title: Suicide by multidrug ingestion: hypothesis on the role played by the self-administration of activated charcoal.

Journal: The American journal of forensic medicine and pathology 20070301

Title: Update on the role of non-opioids for postoperative pain treatment.

Journal: Best practice & research. Clinical anaesthesiology 20070301

Title: Effects of parecoxib and dipyrone on platelet aggregation in patients undergoing meniscectomy: a double-blind, randomized, parallel-group study.

Journal: Clinical therapeutics 20070301

Title: Dipyrone and acetaminophen: correct dosing by parents?

Journal: Sao Paulo medical journal = Revista paulista de medicina 20070104

Title: A population-based case-control teratologic study of oral dipyrone treatment during pregnancy.

Journal: Drug safety 20070101

Title: A nonopioid analgesic acts upon the PAG-RVM axis to reverse inflammatory hyperalgesia.

Journal: The European journal of neuroscience 20070101

Title: Unilateral conjunctival chemosis as a unique symptom of nonsteroidal anti-inflammatory drug intolerance.

Journal: Journal of investigational allergology & clinical immunology 20070101

Title: Isobolographic analyses of the gabapentin-metamizol combination after local peripheral, intrathecal and oral administration in the rat.

Journal: Pharmacology 20070101

Title: Rheumatoid arthritis patients with therapy-induced myelodysplastic syndrome present with long-term remission after recovery.

Journal: Scandinavian journal of rheumatology 20070101

Title: [Combined action of mexidol and non-narcotic analgesics on pain thresholds and emotional stress behavior in animals].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20070101

Title: Bioactive phenolic compounds from aerial parts of Plinia glomerata.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

Title: Simultaneous determination of caffeine, ergotamine, and metamizol in solid pharmaceutical formulation by HPTLC-UV-FLD with mass confirmation by online HPTLC-ESI-MS.

Journal: Journal of chromatographic science 20070101

Title: Acetaminophen, phenacetin and dipyrone do not modulate pressor responses to arachidonic Acid or to pressor agents.

Journal: Pharmacology 20070101

Title: Dipyrone improves small airway function in asthmatic patients with moderate obstruction.

Journal: Journal of investigational allergology & clinical immunology 20070101

Title: Influence of tiagabine on the antinociceptive action of morphine, metamizole and indomethacin in mice.

Journal: Acta poloniae pharmaceutica 20070101

Title: [Antinociceptive effects of the combination metamizol + morphine in rats with intense pain (arthritic gout-type pain produced with AU)].

Journal: Cirugia y cirujanos 20070101

Title: [Comparison of intravenous dipyrone to intravenous metoclopramide in the treatment of acute crisis of migraine: randomized clinical trial].

Journal: Arquivos de neuro-psiquiatria 20061201

Title: [Fulminant pancreatitis--internal point of view].

Journal: Praxis 20061129

Title: [Agranulocytosis in a patient treated with metamizole and clopidogrel].

Journal: Praxis 20061108

Title: Considerations about the theoretically expected crushing strength of tablets from binary powder mixtures: double layer tablets versus arithmetic additivity rule.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20061101

Title: Analgesics for pain after traumatic or orthopaedic surgery: what is the evidence--a systematic review.

Journal: European journal of clinical pharmacology 20061101

Title: Effect of antipyrine on the gastric emptying of liquid in rats.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20061101

Title: Multiple endocrine neoplasia-like syndrome in a horse.

Journal: The Veterinary record 20061014

Title: Paediatric cancer pain management using the WHO analgesic ladder--results of a prospective analysis from 2265 treatment days during a quality improvement study.

Journal: European journal of pain (London, England) 20061001

Title: Epidemiology of adverse cutaneous drug reactions. A prospective study in hospitalized patients.

Journal: Archives of medical research 20061001

Title: Clinical equivalence of IV paracetamol compared to IV dipyrone for postoperative analgesia after surgery for breast cancer.

Journal: Current medical research and opinion 20061001

Title: Dipyrone-induced oligohydramnios and ductus arteriosus restriction.

Journal: The Israel Medical Association journal : IMAJ 20061001

Title: Endogenous opioids are involved in morphine and dipyrone analgesic potentiation in the tail flick test in rats.

Journal: European journal of pharmacology 20060928

Title: [Medical liability in diagnostic errors. Judgement of the High Court of Koblenz on 29.06.2006]].

Journal: Deutsche medizinische Wochenschrift (1946) 20060922

Title: Dipyrone (metamizole) metabolites interfere with HPLC analysis of plasma catecholamines but not with the determination of urinary catecholamines.

Journal: Clinical chemistry 20060901

Title: Dipyrone (metamizole) use in the United States: a lethal tango?

Journal: Southern medical journal 20060901

Title: Metamizole use among Hispanics in Miami: report of a survey conducted in a primary care setting.

Journal: Southern medical journal 20060901

Title: Pattern of dipyrone exposure in Texas, 1998 to 2004.

Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20060901

Title: Prediction of tablet hardness based on near infrared spectra of raw mixed powders by chemometrics.

Journal: Journal of pharmaceutical sciences 20060701

Title: The efficacy of the non-opioid analgesics parecoxib, paracetamol and metamizol for postoperative pain relief after lumbar microdiscectomy.

Journal: Anesthesia and analgesia 20060701

Title: Pharmacodynamics and potential toxicity of intranasally administered dipyrone.

Journal: Biological & pharmaceutical bulletin 20060701

Title: [Intraoperative bronchospasm during paranasal sinus surgery -- indicator of aspirin intolerance syndrome?].

Journal: Laryngo- rhino- otologie 20060601

Title: The Ginkgo biloba extract, EGb 761, fails to reduce brain infarct size in rats after transient, middle cerebral artery occlusion in conditions of unprevented, ischemia-induced fever.

Journal: Phytotherapy research : PTR 20060601

Title: Antipyretic efficacy and tolerability of oral ibuprofen, oral dipyrone and intramuscular dipyrone in children: a randomized controlled trial.

Journal: Sao Paulo medical journal = Revista paulista de medicina 20060504

Title: Does dipyrone have any effect on respiratory function in COPD patients?

Journal: Respiratory medicine 20060501

Title: Characterization of oxalic acid derivatives as new metabolites of metamizol (dipyrone) in incubated hen's egg and human.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060501

Title: Dipyrone-induced granulocytopenia: a case for awareness.

Journal: Pharmacotherapy 20060301

Title: [Acute intermittent porphyria and oral contraception. Case report].

Journal: Ginekologia polska 20060301

Title: Inhibition of human neutrophil oxidative burst by pyrazolone derivatives.

Journal: Free radical biology & medicine 20060215

Title: Use of patch test in fixed drug eruption due to metamizole (Nolotil).

Journal: Contact dermatitis 20060201

Title: Antinociceptive activity of 3-O-beta-d-glucopyranosyl-23,24-dihydrocucurbitacin F from Hintonia standleyana (Rubiaceae).

Journal: Pharmacology, biochemistry, and behavior 20060201

Title: [Postoperative pain management in clinics of otolaryngology].

Journal: Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat 20060101

Title: Dipyrone and aminopyrine are effective scavengers of reactive nitrogen species.

Journal: Redox report : communications in free radical research 20060101

Title: [Parotid phlegmon with involvement of both lobes. Report of a case].

Journal: Anales otorrinolaringologicos ibero-americanos 20060101

Title: Airway smooth muscle relaxations induced by dipyrone.

Journal: Pharmacology 20060101

Title: Intraperitoneal bupivacaine for postoperative pain relief after laparoscopic cholecystectomy.

Journal: Pain medicine (Malden, Mass.) 20060101

Title: [First record of scorpionism caused by Tityus adrianoi Lourenço (Scorpiones: Buthidae)].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20060101

Title: [Comparative efficiency study, safety and usage of tested drugs in patients with renal colic].

Journal: Medicinski arhiv 20060101

Title: Cloning, expression, and functional characterization of human cyclooxygenase-1 splicing variants: evidence for intron 1 retention.

Journal: The Journal of pharmacology and experimental therapeutics 20051201

Title: [Effectiveness of early dipyrone administration on severity of dengue virus infection in a prospective cohort].

Journal: Enfermedades infecciosas y microbiologia clinica 20051201

Title: [Rational diagnostic and therapy of renal colic in the year 2005--what's new?].

Journal: Zentralblatt fur Chirurgie 20051201

Title: Dipyrone: The ban, the justification.

Journal: African journal of medicine and medical sciences 20051201

Title: Intraoperative metamizol as cause for acute anaphylactic collapse.

Journal: European journal of anaesthesiology 20051001

Title: A comparison between IV paracetamol and IV metamizol for postoperative analgesia after retinal surgery.

Journal: Current medical research and opinion 20051001

Title: [Clinical biochemical evaluation of central fatigue with 24-hour continuous exercise].

Journal: Rinsho byori. The Japanese journal of clinical pathology 20050901

Title: Neutropenia, agranulocytosis and dipyrone.

Journal: Sao Paulo medical journal = Revista paulista de medicina 20050901

Title: [Postoperative pain therapy after tonsillectomy in children. An observational study for 7 days].

Journal: HNO 20050801

Title: Metamizol acts as an ATP sensitive potassium channel opener to inhibit the contracting response induced by angiotensin II but not to norepinephrine in rat thoracic aorta smooth muscle.

Journal: Vascular pharmacology 20050801

Title: Pro-drugs in in vitro experiments.

Journal: Anesthesia and analgesia 20050801

Title: [Systemic hypertension at emergency units. The use of symptomatic drugs as choice for management].

Journal: Arquivos brasileiros de cardiologia 20050801

Title: Safety of mixture of morphine with ketamine for postoperative patient-controlled analgesia: an audit with 1026 patients.

Journal: Acta anaesthesiologica Scandinavica 20050701

Title: Antinociception induced by intravenous dipyrone (metamizol) upon dorsal horn neurons: involvement of endogenous opioids at the periaqueductal gray matter, the nucleus raphe magnus, and the spinal cord in rats.

Journal: Brain research 20050628

Title: [Open heart tricuspid valve replacement in a heroin addict Anaesthesiological management].

Journal: Der Anaesthesist 20050601

Title: Drug hypersensitivities: which room for biological tests?

Journal: European annals of allergy and clinical immunology 20050601

Title: Dipyrone and blood dyscrasia revisited: 'non-evidence based medicine'.

Journal: Sao Paulo medical journal = Revista paulista de medicina 20050502

Title: Antinociceptive properties of ethanolic extract and fractions of Pterodon pubescens Benth. seeds.

Journal: Journal of ethnopharmacology 20050408

Title: Intravenous ketoprofen in postoperative pain treatment after major abdominal surgery.

Journal: World journal of surgery 20050401

Title: Pharmacological investigation of the nociceptive response and edema induced by venom of the scorpion Tityus serrulatus.

Journal: Toxicon : official journal of the International Society on Toxinology 20050401

Title: Metamizol (dipyrone, optalgin) in pregnancy, is it safe? A prospective comparative study.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20050401

Title: Effect of piroxicam, metamizol, and S-adenosylmethionine in a murine model of experimental trichomoniasis.

Journal: Parasite (Paris, France) 20050301

Title: [Dual agranulocytosis episode likely resulting from metamizole use].

Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20050301

Title: Agranulocytosis associated with dipyrone (metamizol).

Journal: European journal of clinical pharmacology 20050101

Title: Peristalsis in the Guinea pig small intestine in vitro is impaired by acetaminophen but not aspirin and dipyrone.

Journal: Anesthesia and analgesia 20050101

Title: Absence of re-epithelialization in a fatal case of toxic epidermal necrolysis: is hyperbilirubinemia a culprit?

Journal: Archives of dermatology 20050101

Title: Effect of the GABAB agonist baclofen on dipyrone-induced delayed gastric emptying in rats.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20050101

Title: [Agranulocytosis induced by metamizole and its management with granulocyte growth factor].

Journal: Vojnosanitetski pregled 20050101

Title: [Metamizole and pseudo-ephedrine induced acute generalized exanthematous pustulosis].

Journal: Annales de dermatologie et de venereologie 20050101

Title: Simultaneous determination of residues of dipyrone and its major metabolites in milk, bovine muscle, and porcine muscle by liquid chromatography/mass spectrometry.

Journal: Journal of AOAC International 20050101

Title: Drug-induced anaphylaxis : case/non-case study based on an italian pharmacovigilance database.

Journal: Drug safety 20050101

Title: Pancreatitis due to codeine.

Journal: Allergologia et immunopathologia 20050101

Title: [Use of analgesics and aspirin in a Spanish multicenter study].

Journal: Gaceta sanitaria 20050101

Title: [A possible protocol for postoperative management in laparoscopic cholecystectomy].

Journal: Chirurgia (Bucharest, Romania : 1990) 20050101

Title: Influence of antipyretic drugs on the labeling of blood elements with technetium-99m.

Journal: Acta biologica Hungarica 20050101

Title: Antinociceptive effect of selected Mexican traditional medicinal species.

Journal: Proceedings of the Western Pharmacology Society 20050101

Title: The effectiveness of analgesics in traumatic injuries of the extremities.

Journal: Advances in therapy 20050101

Title: Comparison of the effects on spinal reflexes of acetylsalicylate and metamizol in spinalized and normal rats.

Journal: Acta medica (Hradec Kralove) 20050101

Title: Involvement of cholecystokinin in the opioid tolerance induced by dipyrone (metamizol) microinjections into the periaqueductal gray matter of rats.

Journal: Pain 20041101

Title: Dipyrone potentiates morphine-induced antinociception in dipyrone-treated and morphine-tolerant rats.

Journal: European journal of pharmacology 20041011

Title: Non-oliguric acute renal failure and abortion induced by metamizol overdose.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041001

Title: Safety of the new selective cyclooxygenase type 2 inhibitors rofecoxib and celecoxib in patients with anaphylactoid reactions to nonsteroidal anti-inflammatory drugs.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20041001

Title: A prospective study of the incidence of agranulocytosis and aplastic anemia associated with the oral use of metamizole sodium in Poland.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20040901

Title: The flow-cytometric determination of basophil activation induced by aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) is useful for in vitro diagnosis of the NSAID hypersensitivity syndrome.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040901

Title: Sequential supraclavicular brachial plexus block and intravenous regional anaesthesia for upper limb surgery.

Journal: European journal of anaesthesiology 20040901

Title: Alpha 2-adrenoceptors and 5-HT receptors mediate the antinociceptive effect of new pyrazolines, but not of dipyrone.

Journal: European journal of pharmacology 20040802

Title: Effort-reward imbalance and physical health among Japanese workers in a recently downsized corporation.

Journal: International archives of occupational and environmental health 20040801

Title: Delayed reaction urticaria due to trimebutine.

Journal: Allergy 20040701

Title: Topical provocation in fixed drug eruption due to metamizol and naproxen.

Journal: Clinical and experimental dermatology 20040701

Title: Comparison of cizolirtine citrate and metamizol sodium in the treatment of adult acute renal colic: a randomized, double-blind, clinical pilot study.

Journal: Clinical therapeutics 20040701

Title: Metamizole sodium-induced severe aplastic anemia and its recovery with a short-course steroid therapy.

Journal: Pediatric hematology and oncology 20040601

Title: Modulatory effect of diclofenac on antispasmodic effect of pitofenone in cholinergic spasm.

Journal: Indian journal of experimental biology 20040601

Title: Effects of celecoxib on acid-challenged gastric mucosa of rats: comparison with metamizol and piroxicam.

Journal: Digestive diseases and sciences 20040601

Title: Characterization of the role of physicochemical factors on the hydrolysis of dipyrone.

Journal: Journal of pharmaceutical and biomedical analysis 20040528

Title: Tetracycline compound placement to prevent dry socket: a postoperative study of 200 impacted mandibular third molars.

Journal: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20040501

Title: Metamizol as a cause of postoperative erythroderma.

Journal: Contact dermatitis 20040501

Title: [Bone marrow aplasia following dipyrone treatment in a patient with Crohn's disease receiving long-term methotrexate].

Journal: Gastroenterologie clinique et biologique 20040501

Title: [Drug-induced headache and pain reduction medication with amitriptyline in an 11-year old pupil].

Journal: Der Nervenarzt 20040501

Title: Evidence for the involvement of metabotropic glutamatergic, neurokinin 1 receptor pathways and protein kinase C in the antinociceptive effect of dipyrone in mice.

Journal: Brain research 20040402

Title: Controlled-release oxycodone is better tolerated than intravenous tramadol/metamizol for postoperative analgesia after retinal-surgery.

Journal: Current eye research 20040401

Title: Randomized trial of the effect of antipyresis by metamizol, propacetamol or external cooling on metabolism, hemodynamics and inflammatory response.

Journal: Intensive care medicine 20040301

Title: An electronic pressure-meter nociception paw test for rats.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040301

Title: An electronic pressure-meter nociception paw test for mice.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040301

Title: [Severe anaphylactic reaction to metamizol during subarachnoid anesthesia].

Journal: Revista espanola de anestesiologia y reanimacion 20040301

Title: [Two cases of anaphylactic shock after metamizol given during postoperative recovery].

Journal: Revista espanola de anestesiologia y reanimacion 20040301

Title: [Selective quantitation of analgin by flow injection chemiluminescence method].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20040201

Title: Does preoperative administration of metamizol (Novalgin) affect postoperative body weight and duration of recovery from ketamine-xylazine anaesthesia in mice undergoing embryo transfer: a preliminary report.

Journal: Laboratory animals 20040101

Title: Effect of dexamethasone and dipyrone on lingual and inferior alveolar nerve hypersensitivity following third molar extractions: preliminary report.

Journal: Journal of orofacial pain 20040101

Title: [Consensus of a group of Mexican experts: efficacy and safety of metamizol (Dipirone)].

Journal: Gaceta medica de Mexico 20040101

Title: Dipyrone overdose.

Journal: Journal of toxicology. Clinical toxicology 20040101

Title: Use of a complex approach for assessment of metamizole sodium and acetylsalicylic acid toxicity, genotoxicity and cytotoxicity.

Journal: Journal of applied toxicology : JAT 20040101

Title: Influence of sertraline on the antinociceptive effect of morphine, metamizol and indomethacin in mice.

Journal: Acta poloniae pharmaceutica 20040101

Title: [Anaphylactic reaction versus carcinoid crisis: the role of octreotide as a vasoconstrictor].

Journal: Revista espanola de anestesiologia y reanimacion 20040101

Title: [Is allergy to nonsteroidal antiinflamatory drugs common in surgical patients?].

Journal: Revista espanola de anestesiologia y reanimacion 20040101

Title: The efficacy and safety of dipyrone (Novalgin) tablets in the treatment of acute migraine attacks: a double-blind, cross-over, randomized, placebo-controlled, multi-center study.

Journal: Functional neurology 20040101

Title: Synergistic interaction between gabapentin and metamizol in the rat formalin test.

Journal: Proceedings of the Western Pharmacology Society 20040101

Title: [Sensitivity to tonic pain and analgin in two lines of mice with knockout genotype].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20040101

Title: The effect of gabapentin on antinociceptive action of analgesics.

Journal: Acta poloniae pharmaceutica 20040101

Title: Specific site involvement in fixed drug eruption.

Journal: Journal of the American Academy of Dermatology 20031201

Title: Nandrolone modulates the non-opioid and opioid analgesia and tolerance/dependence: role of sexual dimorphism.

Journal: Archives of physiology and biochemistry 20031201

Title: Linear regression analysis and its application to the multivariate spectral calibrations for the multiresolution of a ternary mixture of caffeine, paracetamol and metamizol in tablets.

Journal: Journal of pharmaceutical and biomedical analysis 20031124

Title: Inhibition of spinal reflexes by acetylsalicylate and metamizol (dipyrone) in rats.

Journal: Pharmacology 20031101

Title: [Multifocal brain haemorrhage associated with migraine and medication abuse].

Journal: Revista de neurologia 20031101

Title: Associations between oxidative stress levels and total duration of engagement in jobs with exposure to fly ash among workers at municipal solid waste incinerators.

Journal: Mutagenesis 20031101

Title: Extrapleural regional versus systemic analgesia for relieving postthoracotomy pain: a clinical study of bupivacaine compared with metamizol.

Journal: The Journal of thoracic and cardiovascular surgery 20031101

Title: Evidence of the effect of dipyrone on the central nervous system as a determinant of delayed gastric emptying observed in rats after its administration.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20031001

Title: Flow injection amperometric determination of dipyrone in pharmaceutical formulations using a carbon paste electrode.

Journal: Farmaco (Societa chimica italiana : 1989) 20031001

Title: Do endogenous opioids and nitric oxide participate in the anticonvulsant action of dipyrone?

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20030901

Title: Antinociceptive profile of (-)-spectaline: a piperidine alkaloid from Cassia leptophylla.

Journal: Planta medica 20030901

Title: [Children often suffer unnecessary pain. A fever suppository after surgery is not enough!].

Journal: MMW Fortschritte der Medizin 20030821

Title: Multi-pumping flow system for the spectrophotometric determination of dipyrone in pharmaceutical preparations.

Journal: Journal of pharmaceutical and biomedical analysis 20030808

Title: Acute renal failure and oligohydramnios induced by magnesium dypirone (metamizol) in a pregnant woman.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030801

Title: Sustained modelling ability of artificial neural networks in the analysis of two pharmaceuticals (dextropropoxyphene and dipyrone) present in unequal concentrations.

Journal: Analytical and bioanalytical chemistry 20030701

Title: Metamizole-induced acute generalized exanthematous pustulosis.

Journal: Contact dermatitis 20030701

Title: Morphine and dipyrone co-administration delays tolerance development and potentiates antinociception.

Journal: European journal of pharmacology 20030523

Title: Determination of dipyrone in pharmaceutical products by flow injection analysis with potentiometric detection.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030501

Title: Effects of acetylsalicylic acid and metamizol on hyaluronidase activity and sperm characteristics in rams.

Journal: Animal reproduction science 20030415

Title: 'Death due to baclofen and dipyrone ingestion', by de Giovanni N, et all.

Journal: Forensic science international 20030408

Title: Use of CD63 expression as a marker of in vitro basophil activation and leukotriene determination in metamizol allergic patients.

Journal: Allergy 20030401

Title: [Anaphylactic cardiocirculatory failure after intraoperative application of dipyrone].

Journal: Der Anaesthesist 20030401

Title: Dipyrone and agranulocytosis: what is the risk?

Journal: Lancet (London, England) 20030315

Title: Effect of adverse drug reactions on length of stay in surgical intensive care units.

Journal: Critical care medicine 20030301

Title: [Diversity and anti-oxidative effects of bilirubin].

Journal: Seikagaku. The Journal of Japanese Biochemical Society 20030301

Title: [Early extubation with caudal morphine after pediatric heart surgery].

Journal: Revista espanola de anestesiologia y reanimacion 20030201

Title: Effect of metamizol on promyelocytic and terminally differentiated granulocytic cells. Comparative analysis with acetylsalicylic acid and diclofenac.

Journal: Biochemical pharmacology 20030115

Title: Possible involvement of potassium channels in peripheral antinociception induced by metamizol: lack of participation of ATP-sensitive K+ channels.

Journal: Pharmacology, biochemistry, and behavior 20030101

Title: Antinociceptive effects of Cremophor EL orally administered to mice.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20030101

Title: [Postoperative analgesia with tramadol and metamizol. Continual infusion versus patient controlled analgesia].

Journal: Der Anaesthesist 20030101

Title: Delayed skin reactions to metamizol.

Journal: Allergy 20030101

Title: [Combined premedication at adenectomy in children].

Journal: Anesteziologiia i reanimatologiia 20030101

Title: Interaction between metamizol and tramadol in a model of acute visceral pain in rats.

Journal: European journal of pain (London, England) 20030101

Title: [Basophil activation test in the diagnosis of allergy to medicines].

Journal: Anales del sistema sanitario de Navarra 20030101

Title: Influence of felbamate on the antinociceptive action of morphine, metamizol and indomethacin in mice.

Journal: Acta poloniae pharmaceutica 20030101

Title: [Ketorolac vs metamizol preemptive analgesia in children].

Journal: Cirugia y cirujanos 20030101

Title: Allergic cholestatic hepatitis and exanthema induced by metamizole: verification by lymphocyte transformation test.

Journal: Liver 20021201

Title: Gastrointestinal tolerability of metamizol, acetaminophen, and diclofenac in subchronic treatment in rats.

Journal: Digestive diseases and sciences 20021201

Title: Pharmacology of systemic analgesics.

Journal: Best practice & research. Clinical anaesthesiology 20021201

Title: Symptomatic intravenous antipyretic therapy: efficacy of metamizol, diclofenac, and propacetamol.

Journal: Journal of pain and symptom management 20021201

Title: Metabolism of metamizol in early stages of the incubated hen's egg.

Journal: Die Pharmazie 20021201

Title: Dipyrone and agranulocytosis: what is the risk?

Journal: Lancet (London, England) 20021109

Title: Influence of mianserin on the antinociceptive effect of morphine, metamizol and indomethacin in mice.

Journal: Pharmacological research 20021101

Title: COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20021015

Title: Intravenous dipyrone in the acute treatment of migraine without aura and migraine with aura: a randomized, double blind, placebo controlled study.

Journal: Headache 20021001

Title: Intravenous dipyrone for the acute treatment of episodic tension-type headache: a randomized, placebo-controlled, double-blind study.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20021001

Title: [Metamizol versus propacetamol: comparative study of the hemodynamic and antipyretic effects in critically ill patients].

Journal: Revista espanola de anestesiologia y reanimacion 20021001

Title: Pain research. Enzyme might relieve research headache.

Journal: Science (New York, N.Y.) 20020920

Title: Hypothermic and antipyretic effects of 3-methyl- and 3-phenyl-5-hydroxy-5-trichloromethyl-4,5-dihydro-1H-pyrazole-1-carboxyamides in mice.

Journal: European journal of pharmacology 20020913

Title: [Headache and hemodialysis: evaluation of the possible triggering factors and of the treatment].

Journal: Arquivos de neuro-psiquiatria 20020901

Title: Role of prostaglandins and nitric oxide in gastric damage induced by metamizol in rats.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020801

Title: In vitro monitoring sub-nanogram amounts analgin in human urine by its inhibitory of the luminol-periodate chemiluminescence reaction using reagent immobilization release technique.

Journal: Bioorganic & medicinal chemistry 20020701

Title: Agranulocytosis and other blood dyscrasias associated with dipyrone (metamizole).

Journal: European journal of clinical pharmacology 20020701

Title: Bioavailability of two metamizole (dipyrone) solutions as single doses of 2 g versus metamizole capsules.

Journal: International journal of clinical pharmacology and therapeutics 20020701

Title: Metamizole use by Latino immigrants: a common and potentially harmful home remedy.

Journal: Pediatrics 20020601

Title: Effects of dipyrone on inflammatory infiltration and oxidative metabolism in gastric mucosa: comparison with acetaminophen and diclofenac.

Journal: Digestive diseases and sciences 20020601

Title: [Efficacy of three drugs in the treatment of migrainous aura: a randomized placebo-controlled study].

Journal: Arquivos de neuro-psiquiatria 20020601

Title: Anti-inflammatory and antinociceptive properties of dantrolene sodium in rats and mice.

Journal: Pharmacological research 20020601

Title: Reproducible identification of the causative drug of a fixed drug eruption by oral provocation and lesional patch testing.

Journal: Contact dermatitis 20020601

Title: Involvement of ATP-sensitive K(+) channels in the peripheral antinociceptive effect induced by dipyrone.

Journal: European journal of pharmacology 20020524

Title: Chronic gastric ulcer healing in rats subjected to selective and non-selective cyclooxygenase-2 inhibitors.

Journal: European journal of pharmacology 20020503

Title: Stenosis-dependent role of nitric oxide and prostaglandins in chronic renal ischemia.

Journal: American journal of physiology. Renal physiology 20020501

Title: Benzydamine: an alternative nonsteroidal anti-inflammatory drug in patients with nimesulide-induced urticaria.

Journal: Allergy 20020501

Title: [Postoperative pain therapy in urology. A prospective study].

Journal: Der Urologe. Ausg. A 20020501

Title: Hematopoietic growth factors in drug-induced agranulocytosis.

Journal: The Journal of the Association of Physicians of India 20020501

Title: Metamizol potentiates morphine antinociception but not constipation after chronic treatment.

Journal: European journal of pharmacology 20020426

Title: To use or not to use dipyrone?

Journal: Sao Paulo medical journal = Revista paulista de medicina 20020307

Title: Presurgical ketoprofen, but not morphine, dipyrone, diclofenac or tenoxicam, preempts post-incisional mechanical allodynia in rats.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020101

Title: A comparative study of the antipyretic effects of indomethacin and dipyrone in rats.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020101

Title: Pharmacokinetics of oleandomycin in dogs after intravenous or oral administration alone and after pretreatment with metamizole or dexamethasone.

Journal: Veterinary research communications 20020101

Title: Utilization pattern of metamizole in northern Sweden and risk estimates of agranulocytosis.

Journal: Pharmacoepidemiology and drug safety 20020101

Title: [Instrumental evaluation of sensory thresholds in subjects with different pain sensitivity].

Journal: Stomatologiia 20020101

Title: Urticaria - as a problem.

Journal: Allergologia et immunopathologia 20020101

Title: Metamizole intolerance and bronchial asthma.

Journal: Allergologia et immunopathologia 20020101

Title: The incidence of metamizole sodium-induced agranulocytosis in Poland.

Journal: The Journal of international medical research 20020101

Title: Single dose dipyrone for acute renal colic pain.

Journal: The Cochrane database of systematic reviews 20020101

Title: [Cutaneous changes occurring after taking non-steroidal anti-inflammatory drugs--five-years' retrospective studies].

Journal: Przeglad lekarski 20020101

Title: Spectrophotometric multicomponent analysis of a mixture of metamizol, acetaminophen and caffeine in pharmaceutical formulations by two chemometric techniques.

Journal: Journal of pharmaceutical and biomedical analysis 20011201

Title: Amperometric determination of dipyrone in pharmaceutical formulations with a flow cell containing gold electrodes from recordable compact discs.

Journal: Journal of pharmaceutical sciences 20011201

Title: Doctor, there's a fly in my soup! Angiotensin-converting enzyme inhibitors, endogenous opioids and visual hallucinations.

Journal: The Israel Medical Association journal : IMAJ 20011201

Title: Death due to baclofen and dipyrone ingestion.

Journal: Forensic science international 20011115

Title: Limited-sampling strategy models for estimating the pharmacokinetic parameters of 4-methylaminoantipyrine, an active metabolite of dipyrone.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20011101

Title: Antiapoptotic effect of dipyrone on HL-60, Jurkat and Raji cell lines submitted to UV irradiation, arachidonic acid and cycloheximide treatments.

Journal: International immunopharmacology 20011101

Title: To use or not to use dipyrone? Or maybe, Central Station versus ER? That is the question.

Journal: Sao Paulo medical journal = Revista paulista de medicina 20011101

Title: [Postoperative pain therapy with hydromorphone and metamizole. A prospective randomized study in intravenous patient-controlled analgesia (PCA)].

Journal: Der Anaesthesist 20011001

Title: Moderate alcohol consumption reduces urinary 8-hydroxydeoxyguanosine by inducing of uric acid.

Journal: Industrial health 20011001

Title: Use of Neo-melubrina, a banned antipyretic drug, in San Diego, California: a survey of patients and providers.

Journal: The Western journal of medicine 20010901

Title: Oral hygiene and postoperative pain after mandibular third molar surgery.

Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20010901

Title: Generalized reaction after patch testing with metamizol.

Journal: Contact dermatitis 20010901

Title: Impairment of the metabolism of dipyrone in asymptomatic carriers of the hepatitis-B virus does not occur in rapid acetylators.

Journal: European journal of clinical pharmacology 20010901

Title: Tune compounds for electrospray ionisation/in-source collision-induced dissociation with mass spectral library searching.

Journal: Journal of chromatography. A 20010810

Title: Prohemorrhagic potential of dipyrone, ibuprofen, ketorolac, and aspirin: mechanisms associated with blood flow and erythrocyte deformability.

Journal: Journal of cardiovascular pharmacology 20010801

Title: Cromolyn sodium suppresses eosinophilic inflammation in patients with aspirin-intolerant asthma.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010801

Title: Effects of metamizol and magnesium sulfate on enzyme activity of glucose 6-phosphate dehydrogenase from human erythrocyte in vitro and rat erythrocyte in vivo.

Journal: Clinical biochemistry 20010601

Title: [44-year-old patient with thrombocytopenia, multiple organ failure and disseminated intravascular coagulation caused by drug poisoning with paracetamol, metamizole, benzodiazepines and alcohol in attempted suicide].

Journal: Der Internist 20010601

Title: Efficacy and safety of metamizol vs. acetylsalicylic acid in patients with moderate episodic tension-type headache: a randomized, double-blind, placebo- and active-controlled, multicentre study.

Journal: Cephalalgia : an international journal of headache 20010601

Title: [Self medication among patients with musculoskeletal symptoms in Araucanía region].

Journal: Revista medica de Chile 20010601

Title: Antipyretic effects of dipyrone versus ibuprofen versus acetaminophen in children: results of a multinational, randomized, modified double-blind study.

Journal: Clinical pediatrics 20010601

Title: Are we losing good drugs?

Journal: Clinical pediatrics 20010601

Title: Antinociception induced by PAG-microinjected dipyrone (metamizol) in rats: involvement of spinal endogenous opioids.

Journal: Brain research 20010330

Title: Effect of antipyretic drugs in children with malaria.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010301

Title: Exanthema to metamizole.

Journal: Allergy 20010301

Title: The effect of dipyrone on survival of skin flaps.

Journal: Scandinavian journal of plastic and reconstructive surgery and hand surgery 20010301

Title: Intravenous metamizol (Dipyrone) in acute migraine treatment and in episodic tension-type headache--a placebo-controlled study.

Journal: Cephalalgia : an international journal of headache 20010301

Title: Response variability to analgesics: a role for non-specific activation of endogenous opioids.

Journal: Pain 20010215

Title: Postoperative analgesia at home after ambulatory hand surgery: a controlled comparison of tramadol, metamizol, and paracetamol.

Journal: Anesthesia and analgesia 20010201

Title: Antibiotic-induced NSAID intolerance.

Journal: Allergy 20010101

Title: Effect of diazepam and midazolam on the antinociceptive effect of morphine, metamizol and indomethacin in mice.

Journal: Die Pharmazie 20010101

Title: Efficacy and safety of dipyrone versus tramadol in the management of pain after hysterectomy: a randomized, double-blind, multicenter study.

Journal: Regional anesthesia and pain medicine 20010101

Title: [Adequate analgesic sedation: an alternative to general anesthesia in ambulatory settings].

Journal: Anesteziologiia i reanimatologiia 20010101

Title: Single-dose dipyrone for acute postoperative pain.

Journal: The Cochrane database of systematic reviews 20010101

Title: Diclofenac and metamizol in postoperative analgesia in plastic surgery.

Journal: Acta chirurgiae plasticae 20010101

Title: Cutaneous drug reaction case reports: from the world literature.

Journal: American journal of clinical dermatology 20010101

Title: Urticaria induced by meperidine allergy.

Journal: Allergy 20000301

Title: Modifying effects of a mixture of acetaminophen, aspirin, dipyrone and ethenzamide on a multiorgan initiation model and its carcinogenicity in male F344 rats.

Journal: Cancer letters 19990108

Title: Spinal and supraspinal antinociceptive action of dipyrone in formalin, capsaicin and glutamate tests. Study of the mechanism of action.

Journal: European journal of pharmacology 19980326

Title: Use of dipyrone during pregnancy and risk of Wilms' tumor. Brazilian Wilms' Tumor Study Group.

Journal: Epidemiology (Cambridge, Mass.) 19960901

Title: Activation of the arginine-nitric oxide pathway in primary sensory neurons contributes to dipyrone-induced spinal and peripheral analgesia.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 19960601

Title: S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance.

Journal: British journal of pharmacology 19950101

Title: Octreotide dependency and headache: a case report.

Journal: Cephalalgia : an international journal of headache 19940801

Title: [Effects of verapamil on behavioral and microcirculatory disorders in pain syndrome of spinal etiology].

Journal: Biulleten' eksperimental'noi biologii i meditsiny 19900501

Title: Diagnosis of antibody-mediated drug allergy. Pyrazolinone and pyrazolidinedione cross-reactivity relationships.

Journal: Allergy 19871101

Title: Risks of agranulocytosis and aplastic anemia. A first report of their relation to drug use with special reference to analgesics. The International Agranulocytosis and Aplastic Anemia Study.

Journal: JAMA 19861003

Title: Mode of analgesic action of dipyrone: direct antagonism of inflammatory hyperalgesia.

Journal: European journal of pharmacology 19850827

Title: Modifying potential of thirty-one chemicals on the short-term development of gamma-glutamyl transpeptidase-positive foci in diethylnitrosamine-initiated rat liver.

Journal: Gan 19841001

Title: Drug utilization and morbidity statistics for the evaluation of drug safety in Sweden.

Journal: Acta medica Scandinavica. Supplementum 19840101

Title: [Experience with the use of new Bulgarian psychotropic drugs].

Journal: Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) 19820101

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