Name: Name:Ferulenol
Brand: AABLOCKS
SKU: AA006G6L
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA006G6L

Chemical Name: Ferulenol

CAS Number: 6805-34-1

Molecular Formula: C24H30O3

Molecular Weight: 366.4932

MDL Number: MFCD02183471

SMILES: CC(=CCc1c(O)oc2c(c1=O)cccc2)CCC=C(CCC=C(C)C)C

NSC Number: 655150

Properties

Complexity: 645

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 2

Formal Charge: 0

Heavy Atom Count: 27

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 1

Isotope Atom Count: 0

Rotatable Bond Count: 8

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 6.9

Literature fold

Title: Disruption of mitochondrial membrane potential by ferulenol and restoration by propolis extract: antiapoptotic role of propolis.

Journal: Acta biologica Hungarica20091201

Title: Characterization of anti-coagulant properties of prenylated coumarin ferulenol.

Journal: Biochimica et biophysica acta20071001

Title: Ferulenol specifically inhibits succinate ubiquinone reductase at the level of the ubiquinone cycle.

Journal: Biochemical and biophysical research communications20070330

Title: Synthesis and structure-activity relationships of novel warfarin derivatives.

Journal: Bioorganic & medicinal chemistry20070315

Title: Antimycobacterial coumarins from the sardinian giant fennel (Ferula communis).

Journal: Journal of natural products20041201

Title: HPLC-DAD-MS identification of bioactive secondary metabolites from Ferula communis roots.

Journal: Fitoterapia20040601

Title: Farnesyloxycoumarins, a new class of squalene-hopene cyclase inhibitors.

Journal: Bioorganic & medicinal chemistry letters20040419

Title: Microtubule-interacting activity and cytotoxicity of the prenylated coumarin ferulenol.

Journal: Planta medica20021201

Title: Acute toxicity of ferulenol, a 4-hydroxycoumarin isolated from Ferula communis L.

Journal: Veterinary and human toxicology20020201

Title: Lahouel M, et al. Ferulenol specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Biochem Biophys Res Commun. 2007 Mar 30;355(1):252-7.

Title: Mamoci E, et al. Chemical composition and in vitro activity of plant extracts from Ferula communis and Dittrichia viscosa against postharvest fungi. Molecules. 2011 Mar 22;16(3):2609-25.

Title: DrissLamnaouer, et al. Ferulenol and ω-hydroxyferulenol, toxic coumarins from Ferula communis var. genuine. Volume 26, Issue 6, 1987, Pages 1613-1615.

6805-34-1 | Ferulenol