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451-40-1,MFCD27966903
Catalog No.:AA00704F

451-40-1 | Deoxybenzoin

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5g
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$6.00   $4.00
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10g
98%
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$8.00   $6.00
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25g
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100g
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00704F
Chemical Name:
Deoxybenzoin
CAS Number:
451-40-1
Molecular Formula:
C14H12O
Molecular Weight:
196.2445
MDL Number:
MFCD27966903
SMILES:
O=C(c1ccccc1)Cc1ccccc1
Properties
Computed Properties
 
Complexity:
197  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
3.2  

Upstream Synthesis Route

[1]JournalofHeterocyclicChemistry,2011,vol.48,#5,p.1095-1102

[1]Tetrahedron,1985,vol.41,#20,p.4615-4620

[1]JournaloftheChemicalSociety,1957,p.3175,3180

[1]ChemicalandPharmaceuticalBulletin,1998,vol.46,#2,p.199-206

[1]Heterocycles,1997,vol.45,#1,p.1-5

Downstream Synthesis Route

[1]ChemischeBerichte,1888,vol.21,p.1305

[2]Tetrahedron,1968,vol.24,p.3031-3041

[1]ChemischeBerichte,1922,vol.55,p.3518

[1]JustusLiebigsAnnalenderChemie,1899,vol.308,p.156

[1]Patent:DE574840,1931,    Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.19,p.820

[2]ChemicalCommunications,2019,vol.55,p.5922-5925

[1]JournaloftheChemicalSociety,1957,p.3175,3180

Literature

Title: Design, synthesis and molecular simulation studies of dihydrostilbene derivatives as potent tyrosinase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20120901

Title: Antihyperuricemic and nephroprotective effects of resveratrol and its analogues in hyperuricemic mice.

Journal: Molecular nutrition & food research 20120901

Title: Identification of enterodiol as a masker for caffeine bitterness by using a pharmacophore model based on structural analogues of homoeriodictyol.

Journal: Journal of agricultural and food chemistry 20120627

Title: Reactions of microsolvated organic compounds at ambient surfaces: droplet velocity, charge state, and solvent effects.

Journal: Journal of the American Society for Mass Spectrometry 20120601

Title: Design, synthesis, and biological evaluation of chalcone oxime derivatives as potential immunosuppressive agents.

Journal: Bioorganic & medicinal chemistry letters 20120501

Title: Regioselective glucosidation of trans-resveratrol in Escherichia coli expressing glucosyltransferase from Phytolacca americana.

Journal: Biotechnology letters 20120301

Title: (Z)-2-[(4-Methyl-phen-yl)sulfon-yl]-1,2-diphenyl-ethene-selenol.

Journal: Acta crystallographica. Section E, Structure reports online 20120201

Title: Resveratrol exerts dosage and duration dependent effect on human mesenchymal stem cell development.

Journal: PloS one 20120101

Title: Metabolic engineering of yeast and plants for the production of the biologically active hydroxystilbene, resveratrol.

Journal: Journal of biomedicine & biotechnology 20120101

Title: A succinct synthesis of the vaulted biaryl ligand vanol via a dienone-phenol rearrangement.

Journal: Chemistry, an Asian journal 20110801

Title: Stereoselective synthesis of an iodinated resveratrol analog: preliminary bioevaluation studies of the radioiodinated species.

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20110701

Title: 2-Chloro-1,2-diphenyl-ethanone (desyl chloride).

Journal: Acta crystallographica. Section E, Structure reports online 20110501

Title: One step synthesis of 2-hydroxymethylisoflavone and their osteogenic activity.

Journal: Bioorganic & medicinal chemistry letters 20110315

Title: Substrate-controlled chemoselective synthesis and potent cytotoxic activity of novel 5,6,7-triarylpyrido[2,3-d]pyrimidin-4-one derivatives.

Journal: Bioorganic & medicinal chemistry letters 20110301

Title: From cleanroom to desktop: emerging micro-nanofabrication technology for biomedical applications.

Journal: Annals of biomedical engineering 20110201

Title: Chemical analyses of wasp-associated streptomyces bacteria reveal a prolific potential for natural products discovery.

Journal: PloS one 20110101

Title: The preparation of 3,5-dihydroxy-4-isopropylstilbene nanoemulsion and in vitro release.

Journal: International journal of nanomedicine 20110101

Title: Concerted Wolff rearrangement in two simple acyclic diazocarbonyl compounds.

Journal: The journal of physical chemistry. A 20101223

Title: Synthesis and structure-activity relationship study of deoxybenzoins on relaxing effects of porcine coronary artery.

Journal: Journal of agricultural and food chemistry 20100922

Title: Inhibition of cancer cell invasion and metastasis by genistein.

Journal: Cancer metastasis reviews 20100901

Title: N-(2,5-Dimeth-oxy-phen-yl)-N'-[4-(2-hy-droxy-eth-yl)phen-yl]urea.

Journal: Acta crystallographica. Section E, Structure reports online 20100901

Title: Design, synthesis, and immunosuppressive activity of new deoxybenzoin derivatives.

Journal: ChemMedChem 20100705

Title: Metronidazole-deoxybenzoin derivatives as anti-Helicobacter pylori agents with potent inhibitory activity against HPE-induced interleukin-8.

Journal: ChemMedChem 20100705

Title: Supramolecular photochemistry in beta-cyclodextrin hosts: a TREPR, NMR, and CIDNP investigation.

Journal: Langmuir : the ACS journal of surfaces and colloids 20100601

Title: Scirpusin A, a hydroxystilbene dimer from Xinjiang wine grape, acts as an effective singlet oxygen quencher and DNA damage protector.

Journal: Journal of the science of food and agriculture 20100415

Title: Design and synthesis of novel deoxybenzoin derivatives as FabH inhibitors and anti-inflammatory agents.

Journal: Bioorganic & medicinal chemistry letters 20100315

Title: Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors.

Journal: Chinese medicine 20100101

Title: 1-(3,4-Dihydroxy-phen-yl)-2-(4-hydroxy-phen-yl)ethanone.

Journal: Acta crystallographica. Section E, Structure reports online 20100101

Title: The hunt for natural skin whitening agents.

Journal: International journal of molecular sciences 20091201

Title: Desorption electrospray ionization mass spectrometry for monitoring the kinetics of Baeyer-Villiger solid-state organic reactions.

Journal: Journal of the American Society for Mass Spectrometry 20091101

Title: Mechanisms regulating skin pigmentation: the rise and fall of complexion coloration.

Journal: International journal of molecular sciences 20090901

Title: Potential antioxidants and tyrosinase inhibitors from synthetic polyphenolic deoxybenzoins.

Journal: Bioorganic & medicinal chemistry 20090701

Title: An updated review of tyrosinase inhibitors.

Journal: International journal of molecular sciences 20090601

Title: Diethyl (1-hydr-oxy-1,2-diphenyl-ethyl)phospho-nate.

Journal: Acta crystallographica. Section E, Structure reports online 20090601

Title: Amines and oximes derived from deoxybenzoins as Helicobacter pylori urease inhibitors.

Journal: European journal of medicinal chemistry 20090501

Title: A new mild base-catalyzed Mannich reaction of hetero-arylamines in water: highly efficient stereoselective synthesis of beta-aminoketones under microwave heating.

Journal: Organic & biomolecular chemistry 20090407

Title: The phytochemical piceatannol induces the loss of CBL and CBL-associated proteins.

Journal: Molecular cancer therapeutics 20090301

Title: Dimethyl (1-hydr-oxy-1,2-diphenyl-ethyl)phospho-nate.

Journal: Acta crystallographica. Section E, Structure reports online 20090301

Title: Diversity-oriented synthesis of Kröhnke pyridines.

Journal: Journal of combinatorial chemistry 20090101

Title: Photodecomposition profiles of beta-bond cleavage of phenylphenacyl derivatives in the higher triplet excited states during stepwise two-color two-laser flash photolysis.

Journal: The journal of physical chemistry. A 20081113

Title: 1-(5-Chloro-2,4-dihydroxy-phen-yl)-2-(4-ethoxy-phen-yl)ethanone.

Journal: Acta crystallographica. Section E, Structure reports online 20081001

Title: Synthesis, crystal structure and antimicrobial activity of deoxybenzoin derivatives from genistein.

Journal: European journal of medicinal chemistry 20080301

Title: An expeditious synthesis of tamoxifen, a representative SERM (selective estrogen receptor modulator), via the three-component coupling reaction among aromatic aldehyde, cinnamyltrimethylsilane, and beta-chlorophenetole.

Journal: Bioorganic & medicinal chemistry 20071215

Title: Deoxybenzoins are novel potent selective estrogen receptor modulators.

Journal: Steroids 20070901

Title: Polyphenols based on isoflavones as inhibitors of Helicobacter pylori urease.

Journal: Bioorganic & medicinal chemistry 20070601

Title: Resveratrol inhibition of Propionibacterium acnes.

Journal: The Journal of antimicrobial chemotherapy 20070601

Title: Vasorelaxant effect of stilbenes from rhizome extract of rhubarb (Rheum undulatum) on the contractility of rat aorta.

Journal: Phytotherapy research : PTR 20070201

Title: Postembryonic RNAi in Heterorhabditis bacteriophora: a nematode insect parasite and host for insect pathogenic symbionts.

Journal: BMC developmental biology 20070101

Title: 7th International Workshop on the Molecular Biology and Genetics of the Lepidoptera August 20-26, 2006, Orthodox Academy of Crete, Kolympari, Crete, Greece.

Journal: Journal of insect science (Online) 20070101

Title: The effect of cicerfuran, an arylbenzofuran from Cicer bijugum, and related benzofurans and stilbenes on Leishmania aethiopica, L. tropica and L. major.

Journal: Planta medica 20060801

Title: Synthesis of the pyrazole isostere of valdecoxib.

Journal: Die Pharmazie 20060601

Title: Resveratrol inhibits gentamicin-induced mesangial cell contraction.

Journal: Life sciences 20060411

Title: New prenylated metabolites of Deguelia longeracemosa and evaluation of their antimicrobial potential.

Journal: Planta medica 20060301

Title: Regioselective sonochemical synthesis of genistein derivatives.

Journal: Ultrasonics sonochemistry 20060101

Title: Multiple hydride reduction pathways in isoflavonoids.

Journal: Beilstein journal of organic chemistry 20060101

Title: Antioxidant, prooxidant and cytotoxic activity of hydroxylated resveratrol analogues: structure-activity relationship.

Journal: Biochemical pharmacology 20050315

Title: Potent inhibition of recombinant human cytochrome p-450 1A1 by pentamethoxystilbene.

Journal: Journal of toxicology and environmental health. Part A 20041201

Title: Antioxidant activity of hydroxystilbene derivatives in homogeneous solution.

Journal: The Journal of organic chemistry 20041015

Title: Enhancement of tyrosinase inhibition of the extract of Veratrum patulum using cellulase.

Journal: Biotechnology and bioengineering 20040930

Title: Estrogenic effects of resveratrol in breast cancer cells expressing mutant and wild-type estrogen receptors: role of AF-1 and AF-2.

Journal: The Journal of steroid biochemistry and molecular biology 20040301

Title: A new class of phytoestrogens; evaluation of the estrogenic activity of deoxybenzoins.

Journal: Chemistry & biology 20040301

Title: Potent inhibition of human cytochrome P450 1 enzymes by dimethoxyphenylvinyl thiophene.

Journal: Archives of pharmacal research 20040201

Title: Synthesis and antioxidant activity of 4-[2-(3,5-dimethoxyphenyl)ethenyl]-1,2-benzenediol, a metabolite of Sphaerophysa salsula.

Journal: Bioscience, biotechnology, and biochemistry 20031101

Title: Effects of hydroxystilbene derivatives on tyrosinase activity.

Journal: Biochemical and biophysical research communications 20030808

Title: Fluoride-induced chemiluminescent decomposition of 1,2-dioxetanes bearing a phenyl moiety substituted with a methyl having an electron-withdrawing group.

Journal: Chemical communications (Cambridge, England) 20030221

Title: Protective effect of trans-resveratrol on gentamicin-induced nephrotoxicity.

Journal: Antioxidants & redox signaling 20021201

Title: Genistein.

Journal: Phytochemistry 20020601

Title: Oxyresveratrol and hydroxystilbene compounds. Inhibitory effect on tyrosinase and mechanism of action.

Journal: The Journal of biological chemistry 20020503

Title: Induction of apoptosis by 3,4'-dimethoxy-5-hydroxystilbene in human promyeloid leukemic HL-60 cells.

Journal: Planta medica 20020201

Title: X-ray investigations of sulfur-containing fungicides. III. Intramolecular forces governing the conformation of a novel orthorhombic polymorph of benzoylmethyl phenyl sulfone, benzoylmethyl 4-chlorophenyl sulfone and benzoylphenylmethyl phenyl sulfone.

Journal: Acta crystallographica. Section B, Structural science 20011201

Title: A novel tetratricopeptide repeat-containing J-protein localized in a plasma membrane-bound protein complex of the phytopathogenic oomycete Phytophthora megasperma.

Journal: European journal of cell biology 20010801

Title: Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010401

Title: Patch test sensitization to Compositae mix, sesquiterpene-lactone mix, Compositae extracts, laurel leaf, Chlorophorin, Mansonone A, and dimethoxydalbergione.

Journal: American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20010301

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