+1 858-523-8231
Login | Register
menu
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
467214-20-6,MFCD08457919
Catalog No.:AA0071YF

467214-20-6 | Alvespimycin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$53.00   $37.00
- +
5mg
≥98%
in stock  
$166.00   $116.00
- +
10mg
≥98%
in stock  
$279.00   $195.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA0071YF
Chemical Name:
Alvespimycin
CAS Number:
467214-20-6
Molecular Formula:
C32H48N4O8
Molecular Weight:
616.7455
MDL Number:
MFCD08457919
SMILES:
COC1CC(C)CC2=C(NCCN(C)C)C(=O)C=C(C2=O)NC(=O)C(=CC=CC(C(C(=CC(C1O)C)C)OC(=O)N)OC)C
Properties
Computed Properties
 
Complexity:
1230  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Defined Bond Stereocenter Count:
3  
Formal Charge:
0  
Heavy Atom Count:
44  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2  

Literature

Title: Ge J, et al. Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90. J Med Chem. 2006 Jul 27;49(15):4606-15.

Title: Hertlein E, et al. 17-DMAG targets the nuclear factor-kappaB family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical implications of HSP90 inhibition. Blood. 2010 Jul 8;116(1):45-53.

Title: Henke A, et al. Reduced Contractility and Motility of Prostatic Cancer-Associated Fibroblasts after Inhibition of Heat Shock Protein 90. Cancers (Basel). 2016 Aug 24;8(9). pii: E77.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
Submit
SDS
Related Products of 467214-20-6
467214-21-7

467214-21-7

 30562-34-6

30562-34-6

 75747-14-7

75747-14-7

 91700-92-4

91700-92-4

 467214-21-7

467214-21-7

 64202-81-9

64202-81-9
Building Blocks
More >
Historical Records
870065-56-8

870065-56-8
Tags:467214-20-6 Molecular Formula|467214-20-6 MDL|467214-20-6 SMILES|467214-20-6 Alvespimycin
Catalog No.: AA0071YF
467214-20-6,MFCD08457919
467214-20-6 | Alvespimycin
Pack Size： 1mg
Purity： ≥98%
in stock
$53.00 $37.00
Pack Size： 5mg
Purity： ≥98%
in stock
$166.00 $116.00
Pack Size： 10mg
Purity： ≥98%
in stock
$279.00 $195.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA0071YF
Chemical Name: Alvespimycin
CAS Number: 467214-20-6
Molecular Formula: C32H48N4O8
Molecular Weight: 616.7455
MDL Number: MFCD08457919
SMILES: COC1CC(C)CC2=C(NCCN(C)C)C(=O)C=C(C2=O)NC(=O)C(=CC=CC(C(C(=CC(C1O)C)C)OC(=O)N)OC)C
Properties
Complexity: 1230  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 6  
Defined Bond Stereocenter Count: 3  
Formal Charge: 0  
Heavy Atom Count: 44  
Hydrogen Bond Acceptor Count: 10  
Hydrogen Bond Donor Count: 4  
Isotope Atom Count: 0  
Rotatable Bond Count: 8  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2  
Related Products of of 467214-20-6
467214-21-7
467214-21-7
30562-34-6
30562-34-6
75747-14-7
75747-14-7
91700-92-4
91700-92-4
467214-21-7
467214-21-7
64202-81-9
64202-81-9
Building Blocks More >
46376-16-3
46376-16-3
Phenylsulfonyl-sar-oh
AA0072D1 | MFCD00031398
438-67-5
438-67-5
Estra-1,3,5(10)-trien-17-one,3-(sulfooxy)-, sodium salt (1:1)
AA0072TA | MFCD00070035
41110-34-3
41110-34-3
Ethyl 5-methylpyrazine-2-carboxylate
AA007398 | MFCD05662506
196301-98-1
196301-98-1
3-(4-Fluorophenyl)-5-methyl-1,2,4-oxadiazole
AA0073SS | MFCD17214258
124-87-8
124-87-8
Picrotoxin
AA00748P | MFCD00074824
1873-11-6
1873-11-6
4-(2-Hydroxyethyl)-4-azatricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-dione
AA0074TD | MFCD01473492
4071-36-7
4071-36-7
N-Acetyl-l-leucine ethyl ester
AA0075C1 | MFCD09952004
392691-62-2
392691-62-2
[(2,6-Difluorophenyl)methyl](methyl)amine
AA0075TR | MFCD09736889
1184-65-2
1184-65-2
Germane, trichloro-
AA00769V | MFCD00135532
3989-35-3
3989-35-3
Methyl 1,2,3-thiadiazole-4-carboxylate
AA0076P5 | MFCD00955572
Historical Records
870065-56-8
870065-56-8
Submit
© 2017 AA BLOCKS, INC. All rights reserved.