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117620-77-6,MFCD00467359
Catalog No.:AA0077IF

117620-77-6 | 3-Cyano-7-ethoxycoumarin

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1mg
98%
in stock  
$16.00   $11.00
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10mg
98%
in stock  
$56.00   $39.00
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25mg
98%
in stock  
$94.00   $66.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0077IF
Chemical Name:
3-Cyano-7-ethoxycoumarin
CAS Number:
117620-77-6
Molecular Formula:
C12H9NO3
Molecular Weight:
215.2048
MDL Number:
MFCD00467359
SMILES:
CCOc1ccc2c(c1)oc(=O)c(c2)C#N
Properties
Computed Properties
 
Complexity:
366  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
2  
XLogP3:
2.2  

Literature

Title: Potent inhibition of CYP1A2 by Frutinone A, an active ingredient of the broad spectrum antimicrobial herbal extract from P. fruticosa.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20121001

Title: Bioactive hydroperoxyl cembranoids from the Red Sea soft coral Sarcophyton glaucum.

Journal: Marine drugs 20120101

Title: Evaluation of the effects of 18 non-synonymous single-nucleotide polymorphisms of CYP450 2C19 on in vitro drug inhibition potential by a fluorescence-based high-throughput assay.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110901

Title: Functional differences in the cytochrome P450 1 family enzymes from zebrafish (Danio rerio) using heterologously expressed proteins.

Journal: Archives of biochemistry and biophysics 20101001

Title: Assessment of cytochrome P450 fluorometric substrates with rainbow trout and killifish exposed to dexamethasone, pregnenolone-16alpha-carbonitrile, rifampicin, and beta-naphthoflavone.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20100510

Title: Effects of cytochrome P450 inhibitors on the biotransformation of fluorogenic substrates by adult male rat liver microsomes and cDNA-expressed rat cytochrome P450 isoforms.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100201

Title: Inactivation of hepatic enzymes by inhalant nitrite--in vivo and in vitro studies.

Journal: The AAPS journal 20070901

Title: 3D structure modeling of cytochrome P450 2C19 and its implication for personalized drug design.

Journal: Biochemical and biophysical research communications 20070406

Title: Observational study of hepatic cytochrome P-450 protein expression and activity in summer flounder (Paralichtys dentatus) after combination ormetoprim-sulfadimethoxine treatment.

Journal: Chemotherapy 20070101

Title: Recombinant production of human microsomal cytochrome P450 2D6 in the methylotrophic yeast Pichia pastoris.

Journal: Chembiochem : a European journal of chemical biology 20051101

Title: Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040701

Title: Rapid determination of enzyme activities of recombinant human cytochromes P450, human liver microsomes and hepatocytes.

Journal: Biopharmaceutics & drug disposition 20031201

Title: Cytochrome P450 fluorometric substrates: identification of isoform-selective probes for rat CYP2D2 and human CYP3A4.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020701

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Tags:117620-77-6 Molecular Formula|117620-77-6 MDL|117620-77-6 SMILES|117620-77-6 3-Cyano-7-ethoxycoumarin