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104869-31-0,MFCD11046019
Catalog No.:AA007G1V

104869-31-0 | 1,3,5-Naphthalenetrisulfonicacid, 8,8'-[carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-, sodium salt(1:6)

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1mg
≥90%
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$52.00   $36.00
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5mg
≥90%
in stock  
$168.00   $117.00
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10mg
≥90%
in stock  
$256.00   $179.00
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25mg
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$575.00   $402.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA007G1V
Chemical Name:
1,3,5-Naphthalenetrisulfonicacid, 8,8'-[carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-, sodium salt(1:6)
CAS Number:
104869-31-0
Molecular Formula:
C35H26N4Na6O21S6
Molecular Weight:
1168.9238
MDL Number:
MFCD11046019
SMILES:
O=C(Nc1cccc(c1)C(=O)Nc1ccc(c2c1c(cc(c2)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)Nc1cccc(c1)C(=O)Nc1ccc(c2c1c(cc(c2)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O.[Na].[Na].[Na].[Na].[Na].[Na]
Properties
Computed Properties
 
Complexity:
2270  
Covalently-Bonded Unit Count:
7  
Heavy Atom Count:
72  
Hydrogen Bond Acceptor Count:
21  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
6  

Literature

Title: Falcipain-2 inhibition by suramin and suramin analogues.

Journal: Bioorganic & medicinal chemistry 20130701

Title: Structure-based inhibition of Norovirus RNA-dependent RNA polymerases.

Journal: Journal of molecular biology 20120608

Title: Identification of P2X₃ and P2X₇ purinergic receptors activated by ATP in rat lacrimal gland.

Journal: Investigative ophthalmology & visual science 20110501

Title: Identification of specific inhibitors for a trypanosomatid RNA editing reaction.

Journal: RNA (New York, N.Y.) 20101201

Title: Melanin-concentrating hormone reduces somatolactin release from cultured goldfish pituitary cells.

Journal: The Journal of endocrinology 20091201

Title: Stimulation of alpha2-adrenoceptors suppresses excitatory synaptic transmission in the medial prefrontal cortex of rat.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080801

Title: Suprasternal gland secretion of male short-tailed opossum induces IP3 generation in the vomeronasal organ.

Journal: Biochimica et biophysica acta 20070501

Title: Synthesis and structure-activity relationships of suramin-derived P2Y11 receptor antagonists with nanomolar potency.

Journal: Journal of medicinal chemistry 20051103

Title: Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050706

Title: Role of adenylate and guanylate cyclases in beta1-, beta2-, and beta3-adrenoceptor-mediated relaxation of internal anal sphincter smooth muscle.

Journal: The Journal of pharmacology and experimental therapeutics 20040301

Title: Cooperation in signal transduction of extracellular guanosine 5' triphosphate and nerve growth factor in neuronal differentiation of PC12 cells.

Journal: Neuroscience 20040101

Title: P2X receptor-mediated excitatory synaptic currents in somatosensory cortex.

Journal: Molecular and cellular neurosciences 20031101

Title: Cloning, tissue distribution and functional characterization of the chicken P2X1 receptor.

Journal: FEBS letters 20030102

Title: Role of G protein and protein kinase signalling in influenza virus budding in MDCK cells.

Journal: The Journal of general virology 20021201

Title: Comparative analysis of human and rat S1P(5) (edg8): differential expression profiles and sensitivities to antagonists.

Journal: Biochemical pharmacology 20021015

Title: Purine and pyrimidine (P2) receptors as drug targets.

Journal: Journal of medicinal chemistry 20020912

Title: Cdc25A phosphatase suppresses apoptosis induced by serum deprivation.

Journal: Oncogene 20010727

Title: F Soto, et al. Antagonistic Properties of the Suramin Analogue NF023 at Heterologously Expressed P2X Receptors. Neuropharmacology. 1999 Jan;38(1):141-9.

Title: M Freissmuth, et al. Suramin Analogues as Subtype-Selective G Protein Inhibitors. Mol Pharmacol. 1996 Apr;49(4):602-11.

Title: G Lambrecht, et al. Agonists and Antagonists Acting at P2X Receptors: Selectivity Profiles and Functional Implications. Naunyn Schmiedebergs Arch Pharmacol. 2000 Nov;362(4-5):340-50.

Title: M Silva-Ramos, et al. Activation of Prejunctional P2x2/3 Heterotrimers by ATP Enhances the Cholinergic Tone in Obstructed Human Urinary Bladders. J Pharmacol Exp Ther. 2020 Jan;372(1):63-72.

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Tags:104869-31-0 Molecular Formula|104869-31-0 MDL|104869-31-0 SMILES|104869-31-0 1,3,5-Naphthalenetrisulfonicacid, 8,8'-[carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-, sodium salt(1:6)