153439-40-8,MFCD00865710
Catalog No.:AA007I62

153439-40-8 | 2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid hydrochloride

Pack Size
Purity
Availability
Price(USD)
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1mg
98%
in stock  
$7.00   $5.00
- +
10mg
98%
in stock  
$9.00   $7.00
- +
50mg
98%
in stock  
$12.00   $8.00
- +
1g
97%(HPLC)
in stock  
$45.00   $32.00
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5g
98 - 102% (Assay on anhydrous basis)
in stock  
$100.00   $70.00
- +
25g
98 - 102% (Assay on anhydrous basis)
in stock  
$272.00   $190.00
- +
100g
98 - 102% (Assay on anhydrous basis)
in stock  
$815.00   $570.00
- +
250g
98 - 102% (Assay on anhydrous basis)
in stock  
$1,815.00   $1,270.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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Technical Information
Catalog Number:
AA007I62
Chemical Name:
2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid hydrochloride
CAS Number:
153439-40-8
Molecular Formula:
C32H40ClNO4
Molecular Weight:
538.1173
MDL Number:
MFCD00865710
SMILES:
OC(=O)C(c1ccc(cc1)C(CCCN1CCC(CC1)C(c1ccccc1)(c1ccccc1)O)O)(C)C.Cl
NSC Number:
758678
Properties
Computed Properties
 
Complexity:
678  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
38  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0  
Rotatable Bond Count:
10  
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0  

Downstream Synthesis Route

[1]Patent:WO2011/158262,2011,A1.Locationinpatent:Page/Pagecolumn13

[2]Patent:CN103333100,2016,B.Locationinpatent:Paragraph0023

[3]Patent:WO2003/104197,2003,A1.Locationinpatent:Page15-16

[4]Patent:WO2003/104197,2003,A1.Locationinpatent:Page17

[5]Patent:WO2005/102999,2005,A2.Locationinpatent:Page/Pagecolumn18;19-20;22

[6]Patent:WO2005/102999,2005,A2.Locationinpatent:Page/Pagecolumn22

[7]Patent:WO2005/102999,2005,A2.Locationinpatent:Page/Pagecolumn20

[8]Patent:WO2005/102999,2005,A2.Locationinpatent:Page/Pagecolumn18

[9]Patent:WO2005/102999,2005,A2.Locationinpatent:Page/Pagecolumn18-19

[10]Patent:WO2006/37042,2006,A1.Locationinpatent:Page/Pagecolumn10

[11]Patent:WO2007/7347,2007,A1.Locationinpatent:Page/Pagecolumn10;13-14

[12]Patent:WO2007/135693,2007,A2.Locationinpatent:Page/Pagecolumn19

[13]Patent:WO2009/34582,2009,A2.Locationinpatent:Page/Pagecolumn10

[14]Patent:WO2009/136412,2009,A2.Locationinpatent:Page/Pagecolumn9

[15]Patent:WO2007/110884,2007,A2.Locationinpatent:Page/Pagecolumn6-7;9

[16]Patent:WO2007/110884,2007,A2.Locationinpatent:Page/Pagecolumn7-8

[17]Patent:WO2007/110884,2007,A2.Locationinpatent:Page/Pagecolumn8

[18]Patent:WO2007/110884,2007,A2.Locationinpatent:Page/Pagecolumn8-9

[1]CurrentPatentAssignee:SANOFI-WO2017/68129,2017,A1Locationinpatent:Page/Pagecolumn42;43

[2]CurrentPatentAssignee:SANOFI-WO2017/68129,2017,A1

[1]CurrentPatentAssignee:SUZHOUHEALTHCOLLEGE-CN104876853,2017,BLocationinpatent:Paragraph0050;0051

[1]CurrentPatentAssignee:XIANWANLONGPHARMACEUTICAL-CN114539131,2022,ALocationinpatent:Paragraph0062;0069-0074;0088-0107

Literature

Title: Mechanism of As2O3-Induced Action Potential Prolongation and Using hiPS-CMs to Evaluate the Rescue Efficacy of Drugs With Different Rescue Mechanism.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170801

Title: H1-antihistamines exacerbate high-fat diet-induced hepatic steatosis in wild-type but not in apolipoprotein E knockout mice.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20140715

Title: Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice.

Journal: PloS one 20140101

Title: H(1)-antihistamines and urticaria: how can we predict the best drug for our patient?

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20121001

Title: Effect of intestinal first-pass hydrolysis on the oral bioavailability of an ester prodrug of fexofenadine.

Journal: Journal of pharmaceutical sciences 20120901

Title: Quantification of fexofenadine in biological matrices: a review of bioanalytical methods.

Journal: Biomedical chromatography : BMC 20120801

Title: Exploring novel colon-targeting antihistaminic prodrug for colitis.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20120801

Title: Microdosing clinical study: pharmacokinetic, pharmacogenomic (SLCO2B1), and interaction (grapefruit juice) profiles of celiprolol following the oral microdose and therapeutic dose.

Journal: Journal of clinical pharmacology 20120701

Title: Enhanced systemic exposure of fexofenadine via the intranasal administration of chitosan-coated liposome.

Journal: International journal of pharmaceutics 20120701

Title: Long-lasting inhibition of the intestinal absorption of fexofenadine by cyclosporin A in rats.

Journal: Journal of pharmaceutical sciences 20120701

Title: Influence of Panax ginseng on cytochrome P450 (CYP)3A and P-glycoprotein (P-gp) activity in healthy participants.

Journal: Journal of clinical pharmacology 20120601

Title: The impact of P-glycoprotein mediated efflux on absorption of 11 sedating and less-sedating antihistamines using Caco-2 monolayers.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20120601

Title: Enhancement of clara cell 10-kD protein (CC10) production from nasal epithelial cells by fexofenadine hydrochloride.

Journal: Asian Pacific journal of allergy and immunology 20120601

Title: Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects.

Journal: European journal of clinical pharmacology 20120501

Title: Effects of single therapeutic doses of promethazine, fexofenadine and olopatadine on psychomotor function and histamine-induced wheal- and flare-responses: a randomized double-blind, placebo-controlled study in healthy volunteers.

Journal: Archives of dermatological research 20120501

Title: Preseasonal prophylactic treatment with antihistamines suppresses IL-5 but not IL-33 mRNA expression in the nasal mucosa of patients with seasonal allergic rhinitis caused by Japanese cedar pollen.

Journal: Acta oto-laryngologica 20120401

Title: Different effects of the selective serotonin reuptake inhibitors fluvoxamine, paroxetine, and sertraline on the pharmacokinetics of fexofenadine in healthy volunteers.

Journal: Journal of clinical psychopharmacology 20120401

Title: Structure determination of fexofenadine-α-cyclodextrin complex by quantitative 2D ROESY analysis and molecular mechanics studies.

Journal: Magnetic resonance in chemistry : MRC 20120401

Title: In vitro-in situ permeability and dissolution of fexofenadine with kinetic modeling in the presence of sodium dodecyl sulfate.

Journal: European journal of drug metabolism and pharmacokinetics 20120301

Title: Carbamazepine differentially affects the pharmacokinetics of fexofenadine enantiomers.

Journal: British journal of clinical pharmacology 20120301

Title: A randomized control trail of stepwise treatment with fluticasone propionate nasal spray and fexofenadine hydrochloride tablet for seasonal allergic rhinitis.

Journal: Allergology international : official journal of the Japanese Society of Allergology 20120301

Title: The effects of an H3 receptor antagonist (PF-03654746) with fexofenadine on reducing allergic rhinitis symptoms.

Journal: The Journal of allergy and clinical immunology 20120201

Title: Ketoconazole-associated preferential increase in dopamine D2 receptor occupancy in striatum compared to pituitary in vivo: role for drug transporters?

Journal: Journal of clinical psychopharmacology 20120201

Title: Treatment of acquired perforating dermatosis with cantharidin.

Journal: Archives of dermatology 20120201

Title: Spectrofluorimetric determination of etodolac, moxepril HCl and fexofenadine HCl using europium sensitized fluorescence in bulk and pharmaceutical preparations.

Journal: Journal of fluorescence 20120101

Title: Effects of bepotastine and fexofenadine on histamine-induced flare, wheal and itch.

Journal: International archives of allergy and immunology 20120101

Title: Adaptation and validation of the Urticaria Patient Daily Diary for adolescents.

Journal: Allergy and asthma proceedings 20120101

Title: The effect of antihistamines on seizures induced by increasing-current electroshocks: ketotifen, but not olopatadine, promotes the seizures in infant rats.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Development of a highly sensitive methodology for quantitative determination of fexofenadine in a microdose study by multiple injection method using ultra-high performance liquid chromatography with tandem mass spectrometry.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Comparison of nasal steroid with antihistamine in prophylactic treatment against pollinosis using an environmental challenge chamber.

Journal: Allergy and asthma proceedings 20120101

Title: Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example.

Journal: Rapid communications in mass spectrometry : RCM 20111215

Title: Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111120

Title: Ameliorating effect of Yokukansan on the development of atopic dermatitis-like lesions and scratching behavior in socially isolated NC/Nga mice.

Journal: Archives of dermatological research 20111101

Title: Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters.

Journal: Molecular pharmaceutics 20111003

Title: Evaluation of the genotoxicity and cytotoxicity of fexofenadine in cultured human peripheral blood lymphocytes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20111001

Title: Assessment of fexofenadine hydrochloride permeability and dissolution with an anionic surfactant using Caco-2 cells.

Journal: Die Pharmazie 20111001

Title: Quantification of the transporter substrate fexofenadine in cell lysates by liquid chromatography/tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20110830

Title: Histaminergic modulation of acetylcholine-induced γ oscillations in rat hippocampus.

Journal: Neuroreport 20110803

Title: Buspirone, fexofenadine, and omeprazole: quantification of probe drugs and their metabolites in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20110715

Title: In brief: fexofenadine (Allegra) and fruit juice.

Journal: The Medical letter on drugs and therapeutics 20110530

Title: The discovery of phthalazinone-based human H1 and H3 single-ligand antagonists suitable for intranasal administration for the treatment of allergic rhinitis.

Journal: Journal of medicinal chemistry 20110414

Title: Poloxamer/cyclodextrin/chitosan-based thermoreversible gel for intranasal delivery of fexofenadine hydrochloride.

Journal: Journal of pharmaceutical sciences 20110201

Title: The effects of the SLCO2B1 c.1457C > T polymorphism and apple juice on the pharmacokinetics of fexofenadine and midazolam in humans.

Journal: Pharmacogenetics and genomics 20110201

Title: Effect of histamine H1 receptor antagonists on TARC/CCL17 and MDC/CCL22 production from CD14+ cells induced by antigenic stimulation in vitro.

Journal: International archives of allergy and immunology 20110101

Title: The effect of histamine on ciliary beat frequency in the acute phase of allergic rhinitis.

Journal: American journal of otolaryngology 20110101

Title: Intranasal phototherapy is more effective than fexofenadine hydrochloride in the treatment of seasonal allergic rhinitis: results of a pilot study.

Journal: Photochemistry and photobiology 20110101

Title: Urticaria due to antihistamines.

Journal: Journal of investigational allergology & clinical immunology 20110101

Title: Analysis of fexofenadine in pharmaceutical formulations using tris(1,10-phenanthroline)-ruthenium(II) peroxydisulphate chemiluminescence system in a multichip device.

Journal: Luminescence : the journal of biological and chemical luminescence 20110101

Title: Development of a novel high-throughput analytical methodology, multiple injection method, for quantitative analysis in drug metabolism and pharmacokinetic studies using liquid chromatography with tandem mass spectrometry.

Journal: Biological & pharmaceutical bulletin 20110101

Title: Improvement of effect of water-in-oil microemulsion as an oral delivery system for fexofenadine: in vitro and in vivo studies.

Journal: International journal of nanomedicine 20110101

Title: Systematic review on the efficacy of fexofenadine in seasonal allergic rhinitis: a meta-analysis of randomized, double-blind, placebo-controlled clinical trials.

Journal: International archives of allergy and immunology 20110101

Title: Regional absorption of fexofenadine in rat intestine.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20101223

Title: Rational quantitative structure-activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands.

Journal: Chemico-biological interactions 20101205

Title: 20(S)-ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: a case for herb-drug interactions.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Influence of drug-transporter polymorphisms on the pharmacokinetics of fexofenadine enantiomers.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20101101

Title: Pharmacokinetics of fexofenadine following LPS administration to rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20101101

Title: Fruit juice inhibition of uptake transport: a new type of food-drug interaction.

Journal: British journal of clinical pharmacology 20101101

Title: The relationship between the drug concentration profiles in plasma and the drug doses in the colon.

Journal: Chemical & pharmaceutical bulletin 20101001

Title: Efficacy of leukotriene antagonists as concomitant therapy in allergic rhinitis.

Journal: The Laryngoscope 20100901

Title: A quantitative structure-activity relationship for the modulation effects of flavonoids on p-glycoprotein-mediated transport.

Journal: Chemical & pharmaceutical bulletin 20100901

Title: Preparation and evaluation of fexofenadine microemulsions for intranasal delivery.

Journal: International journal of pharmaceutics 20100816

Title: Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.

Journal: The Journal of clinical investigation 20100802

Title: Effect of metronidazole on the pharmacokinetics of fexofenadine, a P-glycoprotein substrate, in healthy male volunteers.

Journal: European journal of clinical pharmacology 20100701

Title: Melt-in-mouth pellets of fexofenadine hydrochloride using crospovidone as an extrusion-spheronisation aid.

Journal: AAPS PharmSciTech 20100601

Title: Pharmacokinetics of fexofenadine: evaluation of a microdose and assessment of absolute oral bioavailability.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100512

Title: The effects of bilastine compared with cetirizine, fexofenadine, and placebo on allergen-induced nasal and ocular symptoms in patients exposed to aeroallergen in the Vienna Challenge Chamber.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100501

Title: Preparation and evaluation of spray-dried hyaluronic acid microspheres for intranasal delivery of fexofenadine hydrochloride.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100416

Title: Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.

Journal: Clinical pharmacokinetics 20100401

Title: Microdose study of a P-glycoprotein substrate, fexofenadine, using a non-radioisotope-labelled drug and LC/MS/MS.

Journal: Journal of clinical pharmacy and therapeutics 20100401

Title: Effect of piperine, a major component of black pepper, on the intestinal absorption of fexofenadine and its implication on food-drug interaction.

Journal: Journal of food science 20100401

Title: Measurement of fexofenadine concentration in micro-sample human plasma by a rapid and sensitive LC-MS/MS employing protein precipitation: application to a clinical pharmacokinetic study.

Journal: Biomedical chromatography : BMC 20100301

Title: Development of a novel system for estimating human intestinal absorption using Caco-2 cells in the absence of esterase activity.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100201

Title: Validation and application of a liquid chromatography-tandem mass spectrometric method for quantification of the drug transport probe fexofenadine in human plasma using 96-well filter plates.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201

Title: Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H.

Journal: International archives of allergy and immunology 20100101

Title: Clinical pharmacokinetics of fexofenadine enantiomers.

Journal: Expert opinion on drug metabolism & toxicology 20100101

Title: Tramadol-induced seizurogenic effect: a possible role of opioid-dependent histamine H1 receptor activation-linked mechanism.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20100101

Title: [Administration of premedication with fexofenadine for paclitaxel-induced hypersensitive reactions in breast cancer patients complicated with closed-angle glaucoma].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20100101

Title: Simultaneous determination of gliquidone, fexofenadine, buclizine, and levocetirizine in dosage formulation and human serum by RP-HPLC.

Journal: Journal of chromatographic science 20100101

Title: N-(3,4-dimethoxyphenethyl)-4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2[1H]-yl)-6,7-dimethoxyquinazolin-2-amine (CP-100,356) as a 'chemical knock-out equivalent' to assess the impact of efflux transporters on oral drug absorption in the rat.

Journal: Journal of pharmaceutical sciences 20091201

Title: Effects of the P-glycoprotein inducer carbamazepine on fexofenadine pharmacokinetics.

Journal: Therapeutic drug monitoring 20091201

Title: Assessment of the antiobstructive effect of fexofenadine on nasal allergy challenge in patients with seasonal allergic rhinitis.

Journal: Asian Pacific journal of allergy and immunology 20091201

Title: Leukotriene receptor antagonist in the treatment of childhood allergic rhinitis--a randomized placebo-controlled study.

Journal: Pediatric pulmonology 20091101

Title: Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist.

Journal: The Journal of toxicological sciences 20091001

Title: ESRD impairs nonrenal clearance of fexofenadine but not midazolam.

Journal: Journal of the American Society of Nephrology : JASN 20091001

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Comparing the stimulant effects of the H1-antagonist fexofenadine with 2 psychostimulants, modafinil and methylphenidate.

Journal: Journal of clinical psychopharmacology 20091001

Title: Integration of preclinical and clinical data with pharmacokinetic modeling and simulation to evaluate fexofenadine as a probe for hepatobiliary transport function.

Journal: Pharmaceutical research 20090801

Title: Ureteral stones due to systemic mastocytosis: diagnostic and therapeutic characteristics.

Journal: Urological research 20090801

Title: Effect of St John's wort on the disposition of fexofenadine in the isolated perfused rat liver.

Journal: The Journal of pharmacy and pharmacology 20090801

Title: Fexofenadine: biochemical, pharmacokinetic and pharmacodynamic properties and its unique role in allergic disorders.

Journal: Expert opinion on drug metabolism & toxicology 20090701

Title: Allergies in India: a study on medication compliance.

Journal: Journal of the Indian Medical Association 20090701

Title: Pharmacokinetic drug interaction between fexofenadine and fluvastatin mediated by organic anion-transporting polypeptides in rats.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628

Title: Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers.

Journal: European journal of clinical pharmacology 20090601

Title: Effects of pranlukast hydrate on airway hyperresponsiveness in non-asthmatic patients with Japanese cedar pollinosis.

Journal: Allergology international : official journal of the Japanese Society of Allergology 20090601

Title: Fexofenadine hydrochloride enhances the efficacy of contact immunotherapy for extensive alopecia areata: Retrospective analysis of 121 cases.

Journal: The Journal of dermatology 20090601

Title: Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20090601

Title: Relationship between airborne pollen count and treatment outcome in Japanese cedar pollinosis patients.

Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20090501

Title: A review of the efficacy of desloratadine, fexofenadine, and levocetirizine in the treatment of nasal congestion in patients with allergic rhinitis.

Journal: Clinical therapeutics 20090501

Title: Enantioselective disposition of fexofenadine with the P-glycoprotein inhibitor verapamil.

Journal: British journal of clinical pharmacology 20090501

Title: Multiple H1-antihistamine-induced urticaria.

Journal: The Journal of dermatology 20090401

Title: The inhibition of human multidrug and toxin extrusion 1 is involved in the drug-drug interaction caused by cimetidine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090301

Title: Fexofenadine brain exposure and the influence of blood-brain barrier P-glycoprotein after fexofenadine and terfenadine administration.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090301

Title: IL-16 variability and modulation by antiallergic drugs in a murine experimental allergic rhinitis model.

Journal: International archives of allergy and immunology 20090101

Title: Fluticasone furoate nasal spray is more effective than fexofenadine for nighttime symptoms of seasonal allergy.

Journal: Allergy and asthma proceedings 20090101

Title: Evaluation of the efficacy and safety of olopatadine and fexofenadine compared with placebo in Japanese cedar pollinosis using an environmental exposure unit.

Journal: Journal of investigational allergology & clinical immunology 20090101

Title: Long-term effects of Panax ginseng on disposition of fexofenadine in rats in vivo.

Journal: The American journal of Chinese medicine 20090101

Title: Bioequivalence of fexofenadine tablet formulations assessed in healthy Iranian volunteers.

Journal: Arzneimittel-Forschung 20090101

Title: Mechanistic modeling of hepatic transport from cells to whole body: application to napsagatran and fexofenadine.

Journal: Molecular pharmaceutics 20090101

Title: Efficacy of repeated pretreatment with olopatadine hydrochloride on rhinitis induced by intranasal instillation of toluene-2,4-diisocyanate in rats.

Journal: Pharmacology 20090101

Title: Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast.

Journal: Drugs 20090101

Title: Effects of fexofenadine on inflammatory mediators in nasal lavage fluid in intermittent allergic rhinitis.

Journal: Journal of investigational allergology & clinical immunology 20090101

Title: Psoriasis vulgaris and digestive system disorders: is there a linkage?

Journal: Folia histochemica et cytobiologica 20090101

Title: Involvement of intestinal uptake transporters in the absorption of azithromycin and clarithromycin in the rat.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20081201

Title: Design, data analysis, and simulation of in vitro drug transport kinetic experiments using a mechanistic in vitro model.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20081201

Title: Narrowband ultraviolet B phototherapy is beneficial in antihistamine-resistant symptomatic dermographism: a pilot study.

Journal: Journal of the American Academy of Dermatology 20081101

Title: Potential benefit from an H1-receptor antagonist on postexercise syncope in the heat.

Journal: Medicine and science in sports and exercise 20081101

Title: Validation of the use of nonnaive surgically catheterized rats for pharmacokinetics studies.

Journal: Journal of the American Association for Laboratory Animal Science : JAALAS 20081101

Title: Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics: II. Ritonavir effects on CYP3A and P-glycoprotein activities.

Journal: Clinical pharmacology and therapeutics 20081001

Title: Relative contribution of absorptive and secretory transporters to the intestinal absorption of fexofenadine in rats.

Journal: International journal of pharmaceutics 20080901

Title: Probenecid, but not cystic fibrosis, alters the total and renal clearance of fexofenadine.

Journal: Journal of clinical pharmacology 20080801

Title: Fexofenadine effects on cognitive performance in aviators at ground level and simulated altitude.

Journal: Aviation, space, and environmental medicine 20080801

Title: A simple and rapid high performance liquid chromatographic method with fluorescence detection for the estimation of fexofenadine in rat plasma--application to preclinical pharmacokinetics.

Journal: Talanta 20080715

Title: Evaluation of the antihistamine effects of olopatadine, cetirizine and fexofenadine during a 24 h period: a double-blind, randomized, crossover, placebo-controlled comparison in skin responses induced by histamine iontophoresis.

Journal: Archives of dermatological research 20080701

Title: The effects of fexofenadine at steady-state on sleep architecture: a study using polysomnography in healthy Korean volunteers.

Journal: Expert opinion on pharmacotherapy 20080701

Title: Involvement of multiple efflux transporters in hepatic disposition of fexofenadine.

Journal: Molecular pharmacology 20080501

Title: Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080501

Title: The different effects of itraconazole on the pharmacokinetics of fexofenadine enantiomers.

Journal: British journal of clinical pharmacology 20080501

Title: Modest effect of impaired P-glycoprotein on the plasma concentrations of fexofenadine, quinidine, and loperamide following oral administration in collies.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080501

Title: Time-dependent inhibition of histamine-induced cutaneous responses by oral and intramuscular diphenhydramine and oral fexofenadine.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20080501

Title: Investigation of the inhibitory effects of various drugs on the hepatic uptake of fexofenadine in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080401

Title: Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.

Journal: Methods and findings in experimental and clinical pharmacology 20080401

Title: Fexofenadine in pediatrics: oral tablet and suspension formulations.

Journal: Expert opinion on pharmacotherapy 20080201

Title: Effect of Ginkgo biloba extract on lopinavir, midazolam and fexofenadine pharmacokinetics in healthy subjects.

Journal: Current medical research and opinion 20080201

Title: Isolation and structure elucidation of photodegradation products of fexofenadine.

Journal: Journal of pharmaceutical and biomedical analysis 20080122

Title: Development and validation of a rapid RP-HPLC method for the determination of cetirizine or fexofenadine with pseudoephedrine in binary pharmaceutical dosage forms.

Journal: Journal of pharmaceutical and biomedical analysis 20080122

Title: Multidrug resistance-associated protein 2 is primarily responsible for the biliary excretion of fexofenadine in mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080101

Title: Fexofenadine downmodulates antigen-presenting ability of murine epidermal Langerhans cells.

Journal: Journal of dermatological science 20080101

Title: Atopic cough-like cough hypersensitivity caused by active sensitization with protein fraction of Aspergillus restrictus strain A-17.

Journal: Pulmonary pharmacology & therapeutics 20080101

Title: Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review.

Journal: Clinical pharmacokinetics 20080101

Title: Non-interventional study comparing treatment satisfaction in patients treated with antihistamines.

Journal: Clinical drug investigation 20080101

Title: Pharmacokinetics, safety and tolerability of an oral suspension of fexofenadine for children with allergic rhinitis.

Journal: Allergy and asthma proceedings 20080101

Title: Comparative efficacy of levocetirizine, desloratidine and fexofenadine by histamine wheal suppression test.

Journal: Indian journal of dermatology, venereology and leprology 20080101

Title: Loratadine provides early symptom control in seasonal allergic rhinitis.

Journal: Allergy and asthma proceedings 20080101

Title: Visualization of first-pass drug metabolism of terfenadine by MALDI-imaging mass spectrometry.

Journal: Drug metabolism letters 20080101

Title: Alternative and improved method for the simultaneous determination of fexofenadine and pseudoephedrine in their combined tablet formulation.

Journal: Journal of pharmaceutical and biomedical analysis 20071221

Title: Antihistamine and sodium cromoglycate medication for food cold water exercise-induced anaphylaxis.

Journal: Allergy 20071201

Title: [Linear dermatitis due to shiitake mushrooms].

Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20071201

Title: Two cases of alopecia areata responsive to fexofenadine.

Journal: The Journal of dermatology 20071201

Title: Safety and tolerability of fexofenadine hydrochloride, 15 and 30 mg, twice daily in children aged 6 months to 2 years with allergic rhinitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20071201

Title: Laser ablation electrospray ionization for atmospheric pressure, in vivo, and imaging mass spectrometry.

Journal: Analytical chemistry 20071101

Title: Fexofenadine/cyclodextrin inclusion complexation: phase solubility, thermodynamic, physicochemical, and computational analysis.

Journal: Drug development and industrial pharmacy 20071101

Title: Microdose clinical trial: quantitative determination of fexofenadine in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015

Title: Suppressive activity of fexofenadine hydrochloride on nitric oxide production in-vitro and in-vivo.

Journal: The Journal of pharmacy and pharmacology 20071001

Title: Safety and tolerability of fexofenadine for the treatment of allergic rhinitis in children 2 to 5 years old.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20071001

Title: Formaldehyde-induced urticarial vasculitis.

Journal: The Australasian journal of dermatology 20070801

Title: Combination therapy using fexofenadine, disodium cromoglycate, and a hypoallergenic amino acid-based formula induced remission in a patient with steroid-dependent, chronically active ulcerative colitis.

Journal: International journal of colorectal disease 20070701

Title: Bioequivalence of two fexofenadine formulations in healthy human volunteers after single oral administration.

Journal: Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20070601

Title: Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice.

Journal: Clinical pharmacology and therapeutics 20070401

Title: Effect of oral ketoconazole on intestinal first-pass effect of midazolam and fexofenadine in cynomolgus monkeys.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070301

Title: Intestinal drug transporter expression and the impact of grapefruit juice in humans.

Journal: Clinical pharmacology and therapeutics 20070301

Title: Pharmacokinetics of fexofenadine enantiomers in healthy subjects.

Journal: Chirality 20070301

Title: Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats.

Journal: Biological & pharmaceutical bulletin 20070301

Title: Enhancing effect of surfactants on fexofenadine.HCl transport across the human nasal epithelial cell monolayer.

Journal: International journal of pharmaceutics 20070207

Title: Quantification of fexofenadine in human plasma by liquid chromatography coupled to electrospray tandem mass spectrometry using mosapride as internal standard.

Journal: Biomedical chromatography : BMC 20070201

Title: Simple and reliable HPLC analysis of fexofenadine hydrochloride in tablets and its application to dissolution studies.

Journal: Die Pharmazie 20070201

Title: The effect of fexofenadine hydrochloride on productivity and quality of life in patients with chronic idiopathic urticaria.

Journal: Cutis 20070201

Title: Determination of fexofenadine enantiomers in human plasma with high-performance liquid chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20070117

Title: Inhibition of cytokine-induced expression of T-cell cytokines by antihistamines.

Journal: Journal of investigational allergology & clinical immunology 20070101

Title: Efficacy of fexofenadine versus desloratadine in suppressing histamine-induced wheal and flare.

Journal: Allergy and asthma proceedings 20070101

Title: Direct injection liquid chromatographic technique for simultaneous determination of two antihistaminic drugs and their main metabolites in serum.

Journal: Journal of AOAC International 20070101

Title: Some pharmacokinetic aspects of the lipophilic terfenadine and zwitterionic fexofenadine in humans.

Journal: Drugs in R&D 20070101

Title: The proarrhythmic antihistaminic drug terfenadine increases spontaneous calcium release in human atrial myocytes.

Journal: European journal of pharmacology 20061228

Title: Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs.

Journal: European annals of allergy and clinical immunology 20061201

Title: Lack of dose-dependent effects of itraconazole on the pharmacokinetic interaction with fexofenadine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20061101

Title: Treatment of allergic rhinitis can improve blood pressure control.

Journal: Journal of human hypertension 20061101

Title: New antihistamines: a critical view.

Journal: Jornal de pediatria 20061101

Title: Ultrarush venom desensitization after systemic reactions during conventional venom immunotherapy.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20061101

Title: [Inhibition of histamine-induced wheel after a recommended single dose administration of 10 mg cetirizine, 5 mg desloratadine, 120 i 180 mg fexofenadine, 5 mg levocetirizine and 10 mg loratadine--a randomized, double-blind, placebo controlled trial].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20061101

Title: [The effect of 5-days of cetirizine, desloratadine, fexofenadine 120 and 180 mg, levocetirizine, loratadine treatment on the histamine-induced skin reaction and skin blood flow--a randomized, double-blind, placebo controlled trial].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20061101

Title: Involvement of ionotropic purinergic receptors in the histamine-induced enhancement of the cough reflex sensitivity in guinea pigs.

Journal: European journal of pharmacology 20061010

Title: QT interval prolongation and beyond.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20061001

Title: Onset of action of fexofenadine hydrochloride 60 mg/pseudoephedrine hydrochloride 120 mg in subjects aged 12 years with moderate to severe seasonal allergic rhinitis: a pooled analysis of two single-dose, randomized, double-blind, placebo-controlled allergen exposure unit studies.

Journal: Clinical therapeutics 20061001

Title: Effects of single and multiple doses of itraconazole on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein.

Journal: British journal of clinical pharmacology 20060901

Title: Altered oral bioavailability and pharmacokinetics of P-glycoprotein substrates by coadministration of biochanin A.

Journal: Journal of pharmaceutical sciences 20060901

Title: Hepatobiliary disposition of a drug/metabolite pair: Comprehensive pharmacokinetic modeling in sandwich-cultured rat hepatocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20060801

Title: Facial thermography is a sensitive tool to determine antihistaminic activity: comparison of levocetirizine and fexofenadine.

Journal: British journal of clinical pharmacology 20060801

Title: Alteration of fexofenadine disposition in the rat isolated perfused liver following injection of bacterial lipopolysaccharide.

Journal: Clinical and experimental pharmacology & physiology 20060801

Title: Transporter-mediated intestinal absorption of fexofenadine in rats.

Journal: Drug metabolism and pharmacokinetics 20060801

Title: A combined neurophysiological and behavioural study into the stimulating effects of fexofenadine on performance.

Journal: Journal of psychopharmacology (Oxford, England) 20060701

Title: First-pass effects of verapamil on the intestinal absorption and liver disposition of fexofenadine in the porcine model.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701

Title: Stimulating effects of the antihistamine fexofenadine: testing the dopamine transporter hypothesis.

Journal: Psychopharmacology 20060701

Title: Time-dependent interaction between lopinavir/ritonavir and fexofenadine.

Journal: Journal of clinical pharmacology 20060701

Title: Allergy medication in Japanese volunteers: treatment effect of single doses on nocturnal sleep architecture and next day residual effects.

Journal: Current medical research and opinion 20060701

Title: Efficacy and central nervous system impairment of newer-generation prescription antihistamines in seasonal allergic rhinitis.

Journal: Southern medical journal 20060601

Title: Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060501

Title: Effect of P-glycoprotein on intestinal absorption and brain penetration of antiallergic agent bepotastine besilate.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Once-daily immediate-release fexofenadine and sustained-release pseudoephedrine combination: a new treatment option for allergic rhinitis.

Journal: Expert opinion on pharmacotherapy 20060501

Title: Effects of itraconazole and diltiazem on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein.

Journal: British journal of clinical pharmacology 20060501

Title: Pustular exacerbation of psoriasis due to fexofenadine.

Journal: Clinical and experimental dermatology 20060501

Title: Fexofenadine in horses: pharmacokinetics, pharmacodynamics and effect of ivermectin pretreatment.

Journal: Journal of veterinary pharmacology and therapeutics 20060401

Title: Effect of pretreatment with fexofenadine on the safety of immunotherapy in patients with allergic rhinitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060401

Title: The effect of short- and long-term administration of verapamil on the disposition of cytochrome P450 3A and P-glycoprotein substrates.

Journal: Clinical pharmacology and therapeutics 20060301

Title: Efficacy of fexofenadine in the prophylactic control of cat allergen-induced allergic rhinitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060201

Title: Effect of erythromycin on the absorption of fexofenadine in the jejunum, ileum and colon determined using local intubation in healthy volunteers.

Journal: International journal of clinical pharmacology and therapeutics 20060201

Title: Fexofenadine, an H1-receptor antagonist, partially but rapidly inhibits the itch of contact dermatitis induced by diphenylcyclopropenone in patients with alopecia areata.

Journal: The Journal of dermatology 20060201

Title: Differential effects of fexofenadine on arachidonic acid metabolism in cultured human monocytes.

Journal: Pharmacology 20060101

Title: In vivo pharmacological characterisation of bilastine, a potent and selective histamine H1 receptor antagonist.

Journal: Drugs in R&D 20060101

Title: Efficacy of desloratadine, 5 mg, compared with fexofenadine, 180 mg, in patients with symptomatic seasonal allergic rhinitis.

Journal: Allergy and asthma proceedings 20060101

Title: Saliva secretion in patients with allergic rhinitis.

Journal: International archives of allergy and immunology 20060101

Title: Marketing of a new non-sedating antihistamine (fexofenadine) puts an additional burden on healthcare system resources in Israel.

Journal: The European journal of general practice 20060101

Title: Simultaneous quantification of fexofenadine and pseudoephedrine in human plasma by liquid chromatography/tandem mass spectrometry with electrospray ionization: method development, validation and application to a clinical study.

Journal: Rapid communications in mass spectrometry : RCM 20060101

Title: New evidence of H1-receptor independent COX-2 inhibition by fexofenadine HCl in vitro.

Journal: Pharmacology 20060101

Title: The effect of fexofenadine on pruritus in a mouse model (HR-ADf) of atopic dermatitis.

Journal: The Journal of international medical research 20060101

Title: Selecting the optimal oral antihistamine for patients with allergic rhinitis.

Journal: Drugs 20060101

Title: [Treatment of allergic rhinitis associated with hypothyroidism].

Journal: Vestnik otorinolaringologii 20060101

Title: The methanol disolvate and the dihydrate of fexofenadine, an antihistamine drug.

Journal: Acta crystallographica. Section C, Crystal structure communications 20051201

Title: The efficacy and safety of 30 mg fexofenadine HCl bid in pediatric patients with allergic rhinitis.

Journal: Asian Pacific journal of allergy and immunology 20051201

Title: Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20051001

Title: Effects of fexofenadine hydrochloride in a guinea pig model of antigen-induced rhinitis.

Journal: Pharmacology 20051001

Title: Effects of fexofenadine and hydroxyzine on brake reaction time during car-driving with cellular phone use.

Journal: Human psychopharmacology 20051001

Title: Transport of anti-allergic drugs across the passage cultured human nasal epithelial cell monolayer.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20051001

Title: Treatment of ear pain in pilots in flight.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20051001

Title: The various effects of four H1-antagonists on serum substance P levels in patients with atopic dermatitis.

Journal: The Journal of dermatology 20051001

Title: [Wheat anaphylaxis enhanced by administration of acetylsalicylic acid or by exercise].

Journal: Arerugi = [Allergy] 20051001

Title: Suppression of the histamine-induced wheal and flare response by fexofenadine HCl 60 mg twice daily, loratadine 10 mg once daily and placebo in healthy Japanese volunteers.

Journal: Current medical research and opinion 20050901

Title: Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050901

Title: Determination of fexofenadine in tablets by capillary electrophoresis in free solution and in solution with cyclodextrins as analyte carriers.

Journal: Drug development and industrial pharmacy 20050901

Title: Histamine H1 receptor occupancy and pharmacodynamics of second generation H1-antihistamines.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050901

Title: Development and validation of dissolution tests for fexofenadine hydrochloride capsules and coated tablets.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20050811

Title: Management of seasonal allergic rhinitis: comparative efficacy of the newer-generation prescription antihistamines.

Journal: Journal of the American Academy of Nurse Practitioners 20050801

Title: Effect of itraconazole on the pharmacokinetics and pharmacodynamics of fexofenadine in relation to the MDR1 genetic polymorphism.

Journal: Clinical pharmacology and therapeutics 20050801

Title: The advantages of the Ussing chamber in drug absorption studies.

Journal: Journal of biomolecular screening 20050801

Title: Assessing the therapeutic benefits of antihistamines for the treatment of chronic idiopathic urticaria--a requirement for well-designed comparative clinical studies.

Journal: The Journal of dermatological treatment 20050801

Title: P-glycoprotein plays a major role in the efflux of fexofenadine in the small intestine and blood-brain barrier, but only a limited role in its biliary excretion.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050701

Title: Levocetirizine has a longer duration of action on improving total nasal symptoms score than fexofenadine after single administration.

Journal: British journal of clinical pharmacology 20050701

Title: Once-daily fexofenadine treatment for chronic idiopathic urticaria: a multicenter, randomized, double-blind, placebo-controlled study.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050601

Title: Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1).

Journal: British journal of clinical pharmacology 20050501

Title: Single-dose and steady-state bioequivalence of fexofenadine and pseudoephedrine combination tablets compared with individual formulations in healthy adults.

Journal: Current medical research and opinion 20050501

Title: Preferential downmodulation of certain chemokines by fexofenadine in human keratinocytes.

Journal: Journal of dermatological science 20050401

Title: The efficacy of short-term administration of 3 antihistamines vs placebo under natural exposure to Japanese cedar pollen.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050401

Title: H1 receptor-mediated vasodilatation contributes to postexercise hypotension.

Journal: The Journal of physiology 20050301

Title: CYP3A and P-glycoprotein activity induction with St. John's Wort in healthy volunteers from 6 ethnic populations.

Journal: Journal of clinical pharmacology 20050301

Title: Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: possible role of organic anion transporting polypeptides.

Journal: Clinical pharmacology and therapeutics 20050301

Title: Effect of fruit juices on the oral bioavailability of fexofenadine in rats.

Journal: Journal of pharmaceutical sciences 20050201

Title: Fexofenadine improves the quality of life and work productivity in Japanese patients with seasonal allergic rhinitis during the peak cedar pollinosis season.

Journal: International archives of allergy and immunology 20050201

Title: Evaluation of first-pass cytochrome P4503A (CYP3A) and P-glycoprotein activities using alfentanil and fexofenadine in combination.

Journal: Journal of clinical pharmacology 20050101

Title: Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics.

Journal: Clinical pharmacology and therapeutics 20050101

Title: Minimal important difference (MID) of the Dermatology Life Quality Index (DLQI): results from patients with chronic idiopathic urticaria.

Journal: Health and quality of life outcomes 20050101

Title: Comparative effects of fexofenadine and montelukast on allergen-induced wheal and flare.

Journal: Allergy and asthma proceedings 20050101

Title: Capillary electrophoresis method for fexofenadine hydrochloride in capsules.

Journal: Journal of AOAC International 20050101

Title: Comparative efficacy of cetirizine and fexofenadine for seasonal allergic rhinitis, 5-12 hours postdose, in the environmental exposure unit.

Journal: Allergy and asthma proceedings 20050101

Title: The effect of fexofenadine on expression of intercellular adhesion molecule 1 and induction of apoptosis on peripheral eosinophils.

Journal: Allergy and asthma proceedings 20050101

Title: The utility of mixed-effects covariate analysis in rapid selection of doses in pediatric subjects: a case study with fexofenadine hydrochloride.

Journal: Biopharmaceutics & drug disposition 20041201

Title: Similar rapid onset of action and magnitude of effect of fexofenadine and cetirizine as assessed by inhibition of histamine-induced wheal-and-flare reaction.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20041201

Title: Suppressive activity of fexofenadine hydrochloride on metalloproteinase production from nasal fibroblasts in vitro.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20041201

Title: Microbial oxidation of terfenadine and ebastine into fexofenadine and carebastine.

Journal: Bioorganic & medicinal chemistry letters 20041101

Title: A variant 2677A allele of the MDR1 gene affects fexofenadine disposition.

Journal: Clinical pharmacology and therapeutics 20041101

Title: Effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-induced wheal-and flare-response, sedation, and psychomotor performance.

Journal: Clinical and experimental dermatology 20040901

Title: Venom immunotherapy: adverse reactions and treatment failure.

Journal: Current opinion in allergy and clinical immunology 20040801

Title: Central effects of fexofenadine and cetirizine: measurement of psychomotor performance, subjective sleepiness, and brain histamine H1-receptor occupancy using 11C-doxepin positron emission tomography.

Journal: Journal of clinical pharmacology 20040801

Title: Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans.

Journal: Fundamental & clinical pharmacology 20040801

Title: Validation of the Dermatology Life Quality Index as an outcome measure for urticaria-related quality of life.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040801

Title: Efficacy of azelastine nasal spray in seasonal allergic rhinitis patients who remain symptomatic after treatment with fexofenadine.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040801

Title: A novel membrane sensor for histamine H1-receptor antagonist 'fexofenadine'.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20040801

Title: Transport characteristics of fexofenadine in the Caco-2 cell model.

Journal: Pharmaceutical research 20040801

Title: Determination of fexofenadine in human plasma using 96-well solid phase extraction and HPLC with tandem mass spectrometric detection.

Journal: Journal of pharmaceutical and biomedical analysis 20040629

Title: Liquid chromatographic determination of fexofenadine in human plasma with fluorescence detection.

Journal: Journal of pharmaceutical and biomedical analysis 20040629

Title: Effects of single or combined histamine H1-receptor and leukotriene CysLT1-receptor antagonism on nasal adenosine monophosphate challenge in persistent allergic rhinitis.

Journal: British journal of clinical pharmacology 20040601

Title: Safety and efficacy of oral fexofenadine in children with seasonal allergic rhinitis--a pooled analysis of three studies.

Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20040601

Title: Fexofenadine does not affect omeprazole pharmacokinetics: both are putative P-glycoprotein substrates.

Journal: Basic & clinical pharmacology & toxicology 20040501

Title: Comparative efficacy of wheal-and-flare suppression among various non-sedating antihistamines and the pharmacologic insights to their efficacy.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20040501

Title: Repeated dosing effects of mediator antagonists in inhaled corticosteroid-treated atopic asthmatic patients.

Journal: Chest 20040401

Title: A placebo-controlled evaluation of butterbur and fexofenadine on objective and subjective outcomes in perennial allergic rhinitis.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040401

Title: Comparative effects of desloratadine, fexofenadine, and levocetirizine on nasal adenosine monophosphate challenge in patients with perennial allergic rhinitis.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040401

Title: Lack of association between fexofenadine and rhabdomyolysis.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040401

Title: Mizolastine and fexofenadine modulate cytokine pattern after nasal allergen challenge.

Journal: European annals of allergy and clinical immunology 20040401

Title: Suppressive activity of fexofenadine hydrochloride on thymus- and activation-regulated chemokine production from human peripheral blood leukocytes in response to antigenic stimulation in vitro.

Journal: International archives of allergy and immunology 20040301

Title: The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis.

Journal: International immunopharmacology 20040301

Title: The effects of butterbur on the histamine and allergen cutaneous response.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040201

Title: Assessing patient satisfaction with desloratadine after conversion from loratadine, fexofenadine, or cetirizine.

Journal: Managed care interface 20040201

Title: Anti-inflammatory activity of H1-receptor antagonists: review of recent experimental research.

Journal: Current medical research and opinion 20040101

Title: Comparative efficacy of cetirizine and fexofenadine in the treatment of chronic idiopathic urticaria.

Journal: The Journal of dermatological treatment 20040101

Title: Comparison of the combinations of fexofenadine-pseudoephedrine and loratadine-montelukast in the treatment of seasonal allergic rhinitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040101

Title: Randomized double-blind comparison of cetirizine and fexofenadine after pollen challenge in the Environmental Exposure Unit: duration of effect in subjects with seasonal allergic rhinitis.

Journal: Allergy and asthma proceedings 20040101

Title: Onset of action for the relief of allergic rhinitis symptoms with second-generation antihistamines.

Journal: Allergy and asthma proceedings 20040101

Title: Suppressive activity of fexofenadine hydrochloride on the production of eosinophil chemoattractants from human nasal fibroblasts in vitro.

Journal: Arzneimittel-Forschung 20040101

Title: Development and validation of a liquid chromatographic method for fexofenadine hydrochloride in capsules.

Journal: Journal of AOAC International 20040101

Title: Fexofenadine HCl 60 mg/ pseudoephedrine HCl 120 mg has a 60-minute onset of action in the treatment of seasonal allergic rhinitis symptoms, as assessed in an allergen exposure unit.

Journal: Allergy and asthma proceedings 20040101

Title: [Serum sICAM-1 in patients suffering from allergic rhinitis treated with fexofenadine or fluticasone].

Journal: Pneumonologia i alergologia polska 20040101

Title: Comparative study of acute effects of single doses of fexofenadine, olopatadine, d-chlorpheniramine and placebo on psychomotor function in healthy volunteers.

Journal: Human psychopharmacology 20031201

Title: Multiple transport mechanisms involved in the intestinal absorption and first-pass extraction of fexofenadine.

Journal: Clinical pharmacology and therapeutics 20031101

Title: A study comparing the inhibitory effects of single and repeated oral doses of ebastine and fexofenadine against histamine-induced skin reactivity.

Journal: International archives of allergy and immunology 20031101

Title: Effect of the second-generation antihistamine, fexofenadine, on cough reflex sensitivity and pulmonary function.

Journal: British journal of clinical pharmacology 20031101

Title: Mite-antigen induced immediate reactions in atopic dermatitis are inhibited by daily administration of fexofenadine.

Journal: The Journal of dermatology 20031101

Title: Efficacy and safety profile of fexofenadine HCl: a unique therapeutic option in H1-receptor antagonist treatment.

Journal: The Journal of allergy and clinical immunology 20031001

Title: Effects of fexofenadine and other antihistamines on components of the allergic response: adhesion molecules.

Journal: The Journal of allergy and clinical immunology 20031001

Title: Effects of fexofenadine on T-cell function in a murine model of allergen-induced airway inflammation and hyperresponsiveness.

Journal: The Journal of allergy and clinical immunology 20031001

Title: Is 3-mm less drowsiness important?

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20031001

Title: Fexofenadine hydrochloride, 180 mg, exhibits equivalent efficacy to cetirizine, 10 mg, with less drowsiness in patients with moderate-to-severe seasonal allergic rhinitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20031001

Title: Omalizumab, an anti-IgE antibody, in the treatment of adults and adolescents with perennial allergic rhinitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030801

Title: The effects of fexofenadine on reaction time, decision-making, and driver behavior.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030801

Title: Randomized, double-masked comparison of olopatadine ophthalmic solution, mometasone furoate monohydrate nasal spray, and fexofenadine hydrochloride tablets using the conjunctival and nasal allergen challenge models.

Journal: Clinical therapeutics 20030801

Title: Herbal supplements and skin testing: the lack of effect of commonly used herbal supplements on histamine skin prick testing.

Journal: Allergy 20030601

Title: Supplementation of fexofenadine therapy with nedocromil sodium 2% ophthalmic solution to treat ocular symptoms of seasonal allergic conjunctivitis.

Journal: Clinical & experimental ophthalmology 20030601

Title: H1-antihistaminic activity of cetirizine and fexofenadine in allergic children.

Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20030601

Title: Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study.

Journal: The British journal of dermatology 20030601

Title: Relative potency of fexofenadine HCl 180 mg, loratadine 10 mg, and placebo using a skin test model of wheal-and-flare suppression.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030601

Title: [Clinical aspects of anti-inflammatory action of antihistamines].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030601

Title: Effects of fexofenadine, diphenhydramine, and placebo on performance of the test of variables of attention (TOVA).

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030501

Title: A single-center, randomized, double-blind, placebo-controlled, crossover investigation of the effects of fexofenadine hydrochloride 180 mg alone and with alcohol, with hydroxyzine hydrochloride 50 mg as a positive internal control, on aspects of cognitive and psychomotor function related to driving a car.

Journal: Clinical therapeutics 20030501

Title: Fexofenadine is efficacious and safe in children (aged 6-11 years) with seasonal allergic rhinitis.

Journal: The Journal of allergy and clinical immunology 20030401

Title: The effects of acute doses of fexofenadine, promethazine, and placebo on cognitive and psychomotor function in healthy Japanese volunteers.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030401

Title: [H1 histamine antagonists].

Journal: Revue medicale de Bruxelles 20030401

Title: Decongestant effects of antihistamines: a class effect?

Journal: The Journal of allergy and clinical immunology 20030301

Title: Solar urticaria induced by infrared radiation.

Journal: Clinical and experimental dermatology 20030301

Title: Effect of fexofenadine hydrochloride on cedar pollinosis.

Journal: Auris, nasus, larynx 20030201

Title: Failure of cetirizine and fexofenadine to prevent motion sickness.

Journal: The Annals of pharmacotherapy 20030201

Title: The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique.

Journal: British journal of clinical pharmacology 20030201

Title: Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.

Journal: The Journal of allergy and clinical immunology 20030201

Title: The effects of single-dose fexofenadine, diphenhydramine, and placebo on cognitive performance in flight personnel.

Journal: Aviation, space, and environmental medicine 20030201

Title: Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects.

Journal: Clinical pharmacology and therapeutics 20030101

Title: Internal standard signal suppression by co-eluting analyte in isotope dilution LC-ESI-MS.

Journal: The Analyst 20030101

Title: [Effect of fexofenadine--selective antagonist of histamine receptor (H1) on histamine-induced bronchoconstriction].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030101

Title: Assessing satisfaction with desloratadine and fexofenadine in allergy patients who report dissatisfaction with loratadine.

Journal: BMC family practice 20030101

Title: Roles of histamine in regulation of arousal and cognition: functional neuroimaging of histamine H1 receptors in human brain.

Journal: Life sciences 20021220

Title: Inhibitory effects of oral prednisolone and fexofenadine on skin responses by prick tests with histamine and compound 48/80.

Journal: Journal of dermatological science 20021201

Title: Facial swelling and eosinophilia in a 44-year-old woman.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021201

Title: Effects of fexofenadine on the early response to nasal allergen challenge.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021201

Title: Effect of fexofenadine, a mast cell blocker, in infertile men with significantly increased testicular mast cells.

Journal: Asian journal of andrology 20021201

Title: The antihistamine fexofenadine does not affect I(Kr) currents in a case report of drug-induced cardiac arrhythmia.

Journal: British journal of pharmacology 20021101

Title: Fexofenadine transport in Caco-2 cells: inhibition with verapamil and ritonavir.

Journal: Journal of clinical pharmacology 20021101

Title: Clinical pharmacology of H1-antihistamines in the skin.

Journal: The Journal of allergy and clinical immunology 20021101

Title: Effects of fexofenadine and desloratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20021001

Title: Review of fexofenadine in the treatment of chronic idiopathic urticaria.

Journal: International journal of dermatology 20021001

Title: The use of handheld computers in clinical trials.

Journal: Controlled clinical trials 20021001

Title: Simultaneous determination of fexofenadine and its related compounds by HPLC.

Journal: Journal of pharmaceutical and biomedical analysis 20020720

Title: Chronic urticaria and angioedema.

Journal: The New England journal of medicine 20020718

Title: Role of lung inflammatory mediators as a cause of exercise-induced arterial hypoxemia in young athletes.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20020701

Title: Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness.

Journal: The Journal of allergy and clinical immunology 20020701

Title: Onset of action, efficacy, and safety of fexofenadine 60 mg/pseudoephedrine 120 mg versus placebo in the Atlanta allergen exposure unit.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020701

Title: Comparison of the efficacy of combined fluticasone propionate and olopatadine versus combined fluticasone propionate and fexofenadine for the treatment of allergic rhinoconjunctivitis induced by conjunctival allergen challenge.

Journal: Clinical therapeutics 20020701

Title: In vivo anti-inflammatory effects of fexofenadine in chronic idiopathic urticaria.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20020701

Title: Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block.

Journal: Circulation 20020618

Title: Are herbal products dietary supplements or drugs? An important question for public safety.

Journal: Clinical pharmacology and therapeutics 20020601

Title: Effect of St John's wort on the pharmacokinetics of fexofenadine.

Journal: Clinical pharmacology and therapeutics 20020601

Title: MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine.

Journal: British journal of clinical pharmacology 20020501

Title: Evaluation of cytokines in nasal secretions after nasal antigen challenge: lack of influence of antihistamines.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020501

Title: [Hay fever and asthma. Many of your patients have both].

Journal: MMW Fortschritte der Medizin 20020425

Title: [Chronic idiopathic urticaria: effectiveness of fexofenadine. A double-blind, placebo controlled study with 21 patients].

Journal: Praxis 20020410

Title: A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020201

Title: Are antihistamines useful in managing asthma?

Journal: Current opinion in allergy and clinical immunology 20020201

Title: Determination of fexofenadine in human plasma and urine by liquid chromatography-mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020125

Title: Induction of multidrug resistance-1 and cytochrome P450 mRNAs in human mononuclear cells by rifampin.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020101

Title: Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.

Journal: Clinical pharmacology and therapeutics 20020101

Title: Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine.

Journal: Clinical pharmacokinetics 20020101

Title: [Comparative antihistamine and anti-allergic effects of various antihistamine preparations].

Journal: Terapevticheskii arkhiv 20020101

Title: A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20020101

Title: An evaluation of the effects of high-dose fexofenadine on the central nervous system: a double-blind, placebo-controlled study in healthy volunteers.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20020101

Title: Liquid chromatography/tandem mass spectrometric bioanalysis using normal-phase columns with aqueous/organic mobile phases - a novel approach of eliminating evaporation and reconstitution steps in 96-well SPE.

Journal: Rapid communications in mass spectrometry : RCM 20020101

Title: The use of antihistamines in safety-critical jobs: a meeting report.

Journal: Current medical research and opinion 20020101

Title: Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state.

Journal: Drugs under experimental and clinical research 20020101

Title: Fexofenadine reduces nasal congestion in perennial allergic rhinitis.

Journal: Allergy 20011101

Title: The costs of nonsedating antihistamine therapy for allergic rhinitis in managed care: an updated analysis.

Journal: The American journal of managed care 20011001

Title: Ugly wait at the counter. Insurer pushes to make allergy drugs nonprescription.

Journal: Modern healthcare 20010806

Title: Identification of functionally variant MDR1 alleles among European Americans and African Americans.

Journal: Clinical pharmacology and therapeutics 20010801

Title: Safety of fexofenadine in children treated for seasonal allergic rhinitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010701

Title: Evaluation of the safety of fexofenadine from experience gained in general practice use in England in 1997.

Journal: European journal of clinical pharmacology 20010701

Title: [Seasonal allergic rhinitis. Nasal obstruction can also beh improved].

Journal: MMW Fortschritte der Medizin 20010503

Title: Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol.

Journal: American journal of respiratory and critical care medicine 20010501

Title: Controlled comparison of the efficacy and safety of cetirizine 10 mg o.d. and fexofenadine 120 mg o.d. in reducing symptoms of seasonal allergic rhinitis.

Journal: International archives of allergy and immunology 20010501

Title: A descriptive analysis of the use and cost of new-generation antihistamines in the treatment of allergic rhinitis: a retrospective database analysis.

Journal: The American journal of managed care 20010501

Title: Newer antihistamines.

Journal: The Medical letter on drugs and therapeutics 20010430

Title: Uptake and efflux of the peptidic delta-opioid receptor agonist.

Journal: Neuroscience letters 20010406

Title: Twenty-four hours of activity of cetirizine and fexofenadine in the skin.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010401

Title: Histamine induces exocytosis and IL-6 production from human lung macrophages through interaction with H1 receptors.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010315

Title: Skin concentrations of H1-receptor antagonists.

Journal: The Journal of allergy and clinical immunology 20010301

Title: The effect of rifampin administration on the disposition of fexofenadine.

Journal: Clinical pharmacology and therapeutics 20010301

Title: Fexofenadine hydrochloride--a new anti-histaminic drug.

Journal: The Israel Medical Association journal : IMAJ 20010301

Title: Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: a randomized, placebo-controlled, parallel-group study.

Journal: Clinical therapeutics 20010301

Title: Fixed solar urticaria to visible light successfully treated with fexofenadine.

Journal: Photodermatology, photoimmunology & photomedicine 20010201

Title: Multicenter study of the efficacy and safety of fexofenadine 60 mg. twice daily in 108 Thai patients with chronic idiopathic urticaria.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20010201

Title: Comparison of montelukast and fexofenadine for chronic idiopathic urticaria.

Journal: Archives of dermatology 20010101

Title: Suppression of the early and late cutaneous allergic responses using fexofenadine and montelukast.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010101

Title: Histamine-induced activation of human lung macrophages.

Journal: International archives of allergy and immunology 20010101

Title: [The effect of second generation histamine antagonists on the heart].

Journal: Pneumonologia i alergologia polska 20010101

Title: [Efficacy and safety of fexofenadine and cetirizine in the treatment of allergic rhinitis].

Journal: Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20010101

Title: Fexofenadine HCl is safe and effective for treatment of chronic idiopathic urticaria.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20000501

Title: Sedation with 'non-sedating' antihistamines: four prescription-event monitoring studies in general practice.

Journal: BMJ (Clinical research ed.) 20000429

Title: Severe cardiac arrhythmia on fexofenadine?

Journal: Prescrire international 20000201

Title: Fexofenadine and prolonged QT intervals.

Journal: Nursing 19990901

Title: QT lengthening and life-threatening arrhythmias associated with fexofenadine.

Journal: Lancet (London, England) 19990320

Title: Fexofenadine.

Journal: Drugs 19980201

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Tags:153439-40-8 Molecular Formula|153439-40-8 MDL|153439-40-8 SMILES|153439-40-8 2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid hydrochloride
Catalog No.: AA007I62
153439-40-8,MFCD00865710
153439-40-8 | 2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid hydrochloride
Pack Size: 1mg
Purity: 98%
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Pack Size: 10mg
Purity: 98%
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Purity: 98%
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Pack Size: 1g
Purity: 97%(HPLC)
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Purity: 98 - 102% (Assay on anhydrous basis)
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$100.00 $70.00
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Purity: 98 - 102% (Assay on anhydrous basis)
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$272.00 $190.00
Pack Size: 100g
Purity: 98 - 102% (Assay on anhydrous basis)
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$815.00 $570.00
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Purity: 98 - 102% (Assay on anhydrous basis)
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Technical Information
Catalog Number: AA007I62
Chemical Name: 2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid hydrochloride
CAS Number: 153439-40-8
Molecular Formula: C32H40ClNO4
Molecular Weight: 538.1173
MDL Number: MFCD00865710
SMILES: OC(=O)C(c1ccc(cc1)C(CCCN1CCC(CC1)C(c1ccccc1)(c1ccccc1)O)O)(C)C.Cl
NSC Number: 758678
Properties
Complexity: 678  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 38  
Hydrogen Bond Acceptor Count: 5  
Hydrogen Bond Donor Count: 4  
Isotope Atom Count: 0  
Rotatable Bond Count: 10  
Undefined Atom Stereocenter Count: 1  
Undefined Bond Stereocenter Count: 0  
Downstream Synthesis Route
83799-24-0    138452-21-8 

[1]Patent:WO2011/158262,2011,A1.Locationinpatent:Page/Pagecolumn13

[2]Patent:CN103333100,2016,B.Locationinpatent:Paragraph0023

[3]Patent:WO2003/104197,2003,A1.Locationinpatent:Page15-16

[4]Patent:WO2003/104197,2003,A1.Locationinpatent:Page17

[5]Patent:WO2005/102999,2005,A2.Locationinpatent:Page/Pagecolumn18;19-20;22

[6]Patent:WO2005/102999,2005,A2.Locationinpatent:Page/Pagecolumn22

[7]Patent:WO2005/102999,2005,A2.Locationinpatent:Page/Pagecolumn20

[8]Patent:WO2005/102999,2005,A2.Locationinpatent:Page/Pagecolumn18

[9]Patent:WO2005/102999,2005,A2.Locationinpatent:Page/Pagecolumn18-19

[10]Patent:WO2006/37042,2006,A1.Locationinpatent:Page/Pagecolumn10

[11]Patent:WO2007/7347,2007,A1.Locationinpatent:Page/Pagecolumn10;13-14

[12]Patent:WO2007/135693,2007,A2.Locationinpatent:Page/Pagecolumn19

[13]Patent:WO2009/34582,2009,A2.Locationinpatent:Page/Pagecolumn10

[14]Patent:WO2009/136412,2009,A2.Locationinpatent:Page/Pagecolumn9

[15]Patent:WO2007/110884,2007,A2.Locationinpatent:Page/Pagecolumn6-7;9

[16]Patent:WO2007/110884,2007,A2.Locationinpatent:Page/Pagecolumn7-8

[17]Patent:WO2007/110884,2007,A2.Locationinpatent:Page/Pagecolumn8

[18]Patent:WO2007/110884,2007,A2.Locationinpatent:Page/Pagecolumn8-9

394222-36-7    153439-40-8 

[1]CurrentPatentAssignee:SANOFI-WO2017/68129,2017,A1Locationinpatent:Page/Pagecolumn42;43

[2]CurrentPatentAssignee:SANOFI-WO2017/68129,2017,A1

169280-32-4    153439-40-8 

[1]CurrentPatentAssignee:SUZHOUHEALTHCOLLEGE-CN104876853,2017,BLocationinpatent:Paragraph0050;0051

154477-55-1    153439-40-8 

[1]CurrentPatentAssignee:XIANWANLONGPHARMACEUTICAL-CN114539131,2022,ALocationinpatent:Paragraph0062;0069-0074;0088-0107

Literature fold

Title: Mechanism of As2O3-Induced Action Potential Prolongation and Using hiPS-CMs to Evaluate the Rescue Efficacy of Drugs With Different Rescue Mechanism.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20170801

Title: H1-antihistamines exacerbate high-fat diet-induced hepatic steatosis in wild-type but not in apolipoprotein E knockout mice.

Journal: American journal of physiology. Gastrointestinal and liver physiology20140715

Title: Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice.

Journal: PloS one20140101

Title: H(1)-antihistamines and urticaria: how can we predict the best drug for our patient?

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology20121001

Title: Effect of intestinal first-pass hydrolysis on the oral bioavailability of an ester prodrug of fexofenadine.

Journal: Journal of pharmaceutical sciences20120901

Title: Quantification of fexofenadine in biological matrices: a review of bioanalytical methods.

Journal: Biomedical chromatography : BMC20120801

Title: Exploring novel colon-targeting antihistaminic prodrug for colitis.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society20120801

Title: Microdosing clinical study: pharmacokinetic, pharmacogenomic (SLCO2B1), and interaction (grapefruit juice) profiles of celiprolol following the oral microdose and therapeutic dose.

Journal: Journal of clinical pharmacology20120701

Title: Enhanced systemic exposure of fexofenadine via the intranasal administration of chitosan-coated liposome.

Journal: International journal of pharmaceutics20120701

Title: Long-lasting inhibition of the intestinal absorption of fexofenadine by cyclosporin A in rats.

Journal: Journal of pharmaceutical sciences20120701

Title: Influence of Panax ginseng on cytochrome P450 (CYP)3A and P-glycoprotein (P-gp) activity in healthy participants.

Journal: Journal of clinical pharmacology20120601

Title: The impact of P-glycoprotein mediated efflux on absorption of 11 sedating and less-sedating antihistamines using Caco-2 monolayers.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20120601

Title: Enhancement of clara cell 10-kD protein (CC10) production from nasal epithelial cells by fexofenadine hydrochloride.

Journal: Asian Pacific journal of allergy and immunology20120601

Title: Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects.

Journal: European journal of clinical pharmacology20120501

Title: Effects of single therapeutic doses of promethazine, fexofenadine and olopatadine on psychomotor function and histamine-induced wheal- and flare-responses: a randomized double-blind, placebo-controlled study in healthy volunteers.

Journal: Archives of dermatological research20120501

Title: Preseasonal prophylactic treatment with antihistamines suppresses IL-5 but not IL-33 mRNA expression in the nasal mucosa of patients with seasonal allergic rhinitis caused by Japanese cedar pollen.

Journal: Acta oto-laryngologica20120401

Title: Different effects of the selective serotonin reuptake inhibitors fluvoxamine, paroxetine, and sertraline on the pharmacokinetics of fexofenadine in healthy volunteers.

Journal: Journal of clinical psychopharmacology20120401

Title: Structure determination of fexofenadine-α-cyclodextrin complex by quantitative 2D ROESY analysis and molecular mechanics studies.

Journal: Magnetic resonance in chemistry : MRC20120401

Title: In vitro-in situ permeability and dissolution of fexofenadine with kinetic modeling in the presence of sodium dodecyl sulfate.

Journal: European journal of drug metabolism and pharmacokinetics20120301

Title: Carbamazepine differentially affects the pharmacokinetics of fexofenadine enantiomers.

Journal: British journal of clinical pharmacology20120301

Title: A randomized control trail of stepwise treatment with fluticasone propionate nasal spray and fexofenadine hydrochloride tablet for seasonal allergic rhinitis.

Journal: Allergology international : official journal of the Japanese Society of Allergology20120301

Title: The effects of an H3 receptor antagonist (PF-03654746) with fexofenadine on reducing allergic rhinitis symptoms.

Journal: The Journal of allergy and clinical immunology20120201

Title: Ketoconazole-associated preferential increase in dopamine D2 receptor occupancy in striatum compared to pituitary in vivo: role for drug transporters?

Journal: Journal of clinical psychopharmacology20120201

Title: Treatment of acquired perforating dermatosis with cantharidin.

Journal: Archives of dermatology20120201

Title: Spectrofluorimetric determination of etodolac, moxepril HCl and fexofenadine HCl using europium sensitized fluorescence in bulk and pharmaceutical preparations.

Journal: Journal of fluorescence20120101

Title: Effects of bepotastine and fexofenadine on histamine-induced flare, wheal and itch.

Journal: International archives of allergy and immunology20120101

Title: Adaptation and validation of the Urticaria Patient Daily Diary for adolescents.

Journal: Allergy and asthma proceedings20120101

Title: The effect of antihistamines on seizures induced by increasing-current electroshocks: ketotifen, but not olopatadine, promotes the seizures in infant rats.

Journal: Biological & pharmaceutical bulletin20120101

Title: Development of a highly sensitive methodology for quantitative determination of fexofenadine in a microdose study by multiple injection method using ultra-high performance liquid chromatography with tandem mass spectrometry.

Journal: Biological & pharmaceutical bulletin20120101

Title: Comparison of nasal steroid with antihistamine in prophylactic treatment against pollinosis using an environmental challenge chamber.

Journal: Allergy and asthma proceedings20120101

Title: Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example.

Journal: Rapid communications in mass spectrometry : RCM20111215

Title: Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20111120

Title: Ameliorating effect of Yokukansan on the development of atopic dermatitis-like lesions and scratching behavior in socially isolated NC/Nga mice.

Journal: Archives of dermatological research20111101

Title: Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters.

Journal: Molecular pharmaceutics20111003

Title: Evaluation of the genotoxicity and cytotoxicity of fexofenadine in cultured human peripheral blood lymphocytes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20111001

Title: Assessment of fexofenadine hydrochloride permeability and dissolution with an anionic surfactant using Caco-2 cells.

Journal: Die Pharmazie20111001

Title: Quantification of the transporter substrate fexofenadine in cell lysates by liquid chromatography/tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM20110830

Title: Histaminergic modulation of acetylcholine-induced γ oscillations in rat hippocampus.

Journal: Neuroreport20110803

Title: Buspirone, fexofenadine, and omeprazole: quantification of probe drugs and their metabolites in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis20110715

Title: In brief: fexofenadine (Allegra) and fruit juice.

Journal: The Medical letter on drugs and therapeutics20110530

Title: The discovery of phthalazinone-based human H1 and H3 single-ligand antagonists suitable for intranasal administration for the treatment of allergic rhinitis.

Journal: Journal of medicinal chemistry20110414

Title: Poloxamer/cyclodextrin/chitosan-based thermoreversible gel for intranasal delivery of fexofenadine hydrochloride.

Journal: Journal of pharmaceutical sciences20110201

Title: The effects of the SLCO2B1 c.1457C > T polymorphism and apple juice on the pharmacokinetics of fexofenadine and midazolam in humans.

Journal: Pharmacogenetics and genomics20110201

Title: Effect of histamine H1 receptor antagonists on TARC/CCL17 and MDC/CCL22 production from CD14+ cells induced by antigenic stimulation in vitro.

Journal: International archives of allergy and immunology20110101

Title: The effect of histamine on ciliary beat frequency in the acute phase of allergic rhinitis.

Journal: American journal of otolaryngology20110101

Title: Intranasal phototherapy is more effective than fexofenadine hydrochloride in the treatment of seasonal allergic rhinitis: results of a pilot study.

Journal: Photochemistry and photobiology20110101

Title: Urticaria due to antihistamines.

Journal: Journal of investigational allergology & clinical immunology20110101

Title: Analysis of fexofenadine in pharmaceutical formulations using tris(1,10-phenanthroline)-ruthenium(II) peroxydisulphate chemiluminescence system in a multichip device.

Journal: Luminescence : the journal of biological and chemical luminescence20110101

Title: Development of a novel high-throughput analytical methodology, multiple injection method, for quantitative analysis in drug metabolism and pharmacokinetic studies using liquid chromatography with tandem mass spectrometry.

Journal: Biological & pharmaceutical bulletin20110101

Title: Improvement of effect of water-in-oil microemulsion as an oral delivery system for fexofenadine: in vitro and in vivo studies.

Journal: International journal of nanomedicine20110101

Title: Systematic review on the efficacy of fexofenadine in seasonal allergic rhinitis: a meta-analysis of randomized, double-blind, placebo-controlled clinical trials.

Journal: International archives of allergy and immunology20110101

Title: Regional absorption of fexofenadine in rat intestine.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20101223

Title: Rational quantitative structure-activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands.

Journal: Chemico-biological interactions20101205

Title: 20(S)-ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: a case for herb-drug interactions.

Journal: Drug metabolism and disposition: the biological fate of chemicals20101201

Title: Influence of drug-transporter polymorphisms on the pharmacokinetics of fexofenadine enantiomers.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20101101

Title: Pharmacokinetics of fexofenadine following LPS administration to rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20101101

Title: Fruit juice inhibition of uptake transport: a new type of food-drug interaction.

Journal: British journal of clinical pharmacology20101101

Title: The relationship between the drug concentration profiles in plasma and the drug doses in the colon.

Journal: Chemical & pharmaceutical bulletin20101001

Title: Efficacy of leukotriene antagonists as concomitant therapy in allergic rhinitis.

Journal: The Laryngoscope20100901

Title: A quantitative structure-activity relationship for the modulation effects of flavonoids on p-glycoprotein-mediated transport.

Journal: Chemical & pharmaceutical bulletin20100901

Title: Preparation and evaluation of fexofenadine microemulsions for intranasal delivery.

Journal: International journal of pharmaceutics20100816

Title: Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.

Journal: The Journal of clinical investigation20100802

Title: Effect of metronidazole on the pharmacokinetics of fexofenadine, a P-glycoprotein substrate, in healthy male volunteers.

Journal: European journal of clinical pharmacology20100701

Title: Melt-in-mouth pellets of fexofenadine hydrochloride using crospovidone as an extrusion-spheronisation aid.

Journal: AAPS PharmSciTech20100601

Title: Pharmacokinetics of fexofenadine: evaluation of a microdose and assessment of absolute oral bioavailability.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20100512

Title: The effects of bilastine compared with cetirizine, fexofenadine, and placebo on allergen-induced nasal and ocular symptoms in patients exposed to aeroallergen in the Vienna Challenge Chamber.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]20100501

Title: Preparation and evaluation of spray-dried hyaluronic acid microspheres for intranasal delivery of fexofenadine hydrochloride.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20100416

Title: Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.

Journal: Clinical pharmacokinetics20100401

Title: Microdose study of a P-glycoprotein substrate, fexofenadine, using a non-radioisotope-labelled drug and LC/MS/MS.

Journal: Journal of clinical pharmacy and therapeutics20100401

Title: Effect of piperine, a major component of black pepper, on the intestinal absorption of fexofenadine and its implication on food-drug interaction.

Journal: Journal of food science20100401

Title: Measurement of fexofenadine concentration in micro-sample human plasma by a rapid and sensitive LC-MS/MS employing protein precipitation: application to a clinical pharmacokinetic study.

Journal: Biomedical chromatography : BMC20100301

Title: Development of a novel system for estimating human intestinal absorption using Caco-2 cells in the absence of esterase activity.

Journal: Drug metabolism and disposition: the biological fate of chemicals20100201

Title: Validation and application of a liquid chromatography-tandem mass spectrometric method for quantification of the drug transport probe fexofenadine in human plasma using 96-well filter plates.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20100201

Title: Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H.

Journal: International archives of allergy and immunology20100101

Title: Clinical pharmacokinetics of fexofenadine enantiomers.

Journal: Expert opinion on drug metabolism & toxicology20100101

Title: Tramadol-induced seizurogenic effect: a possible role of opioid-dependent histamine H1 receptor activation-linked mechanism.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20100101

Title: [Administration of premedication with fexofenadine for paclitaxel-induced hypersensitive reactions in breast cancer patients complicated with closed-angle glaucoma].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20100101

Title: Simultaneous determination of gliquidone, fexofenadine, buclizine, and levocetirizine in dosage formulation and human serum by RP-HPLC.

Journal: Journal of chromatographic science20100101

Title: N-(3,4-dimethoxyphenethyl)-4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2[1H]-yl)-6,7-dimethoxyquinazolin-2-amine (CP-100,356) as a 'chemical knock-out equivalent' to assess the impact of efflux transporters on oral drug absorption in the rat.

Journal: Journal of pharmaceutical sciences20091201

Title: Effects of the P-glycoprotein inducer carbamazepine on fexofenadine pharmacokinetics.

Journal: Therapeutic drug monitoring20091201

Title: Assessment of the antiobstructive effect of fexofenadine on nasal allergy challenge in patients with seasonal allergic rhinitis.

Journal: Asian Pacific journal of allergy and immunology20091201

Title: Leukotriene receptor antagonist in the treatment of childhood allergic rhinitis--a randomized placebo-controlled study.

Journal: Pediatric pulmonology20091101

Title: Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist.

Journal: The Journal of toxicological sciences20091001

Title: ESRD impairs nonrenal clearance of fexofenadine but not midazolam.

Journal: Journal of the American Society of Nephrology : JASN20091001

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology20091001

Title: Comparing the stimulant effects of the H1-antagonist fexofenadine with 2 psychostimulants, modafinil and methylphenidate.

Journal: Journal of clinical psychopharmacology20091001

Title: Integration of preclinical and clinical data with pharmacokinetic modeling and simulation to evaluate fexofenadine as a probe for hepatobiliary transport function.

Journal: Pharmaceutical research20090801

Title: Ureteral stones due to systemic mastocytosis: diagnostic and therapeutic characteristics.

Journal: Urological research20090801

Title: Effect of St John's wort on the disposition of fexofenadine in the isolated perfused rat liver.

Journal: The Journal of pharmacy and pharmacology20090801

Title: Fexofenadine: biochemical, pharmacokinetic and pharmacodynamic properties and its unique role in allergic disorders.

Journal: Expert opinion on drug metabolism & toxicology20090701

Title: Allergies in India: a study on medication compliance.

Journal: Journal of the Indian Medical Association20090701

Title: Pharmacokinetic drug interaction between fexofenadine and fluvastatin mediated by organic anion-transporting polypeptides in rats.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20090628

Title: Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers.

Journal: European journal of clinical pharmacology20090601

Title: Effects of pranlukast hydrate on airway hyperresponsiveness in non-asthmatic patients with Japanese cedar pollinosis.

Journal: Allergology international : official journal of the Japanese Society of Allergology20090601

Title: Fexofenadine hydrochloride enhances the efficacy of contact immunotherapy for extensive alopecia areata: Retrospective analysis of 121 cases.

Journal: The Journal of dermatology20090601

Title: Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20090601

Title: Relationship between airborne pollen count and treatment outcome in Japanese cedar pollinosis patients.

Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery20090501

Title: A review of the efficacy of desloratadine, fexofenadine, and levocetirizine in the treatment of nasal congestion in patients with allergic rhinitis.

Journal: Clinical therapeutics20090501

Title: Enantioselective disposition of fexofenadine with the P-glycoprotein inhibitor verapamil.

Journal: British journal of clinical pharmacology20090501

Title: Multiple H1-antihistamine-induced urticaria.

Journal: The Journal of dermatology20090401

Title: The inhibition of human multidrug and toxin extrusion 1 is involved in the drug-drug interaction caused by cimetidine.

Journal: Drug metabolism and disposition: the biological fate of chemicals20090301

Title: Fexofenadine brain exposure and the influence of blood-brain barrier P-glycoprotein after fexofenadine and terfenadine administration.

Journal: Drug metabolism and disposition: the biological fate of chemicals20090301

Title: IL-16 variability and modulation by antiallergic drugs in a murine experimental allergic rhinitis model.

Journal: International archives of allergy and immunology20090101

Title: Fluticasone furoate nasal spray is more effective than fexofenadine for nighttime symptoms of seasonal allergy.

Journal: Allergy and asthma proceedings20090101

Title: Evaluation of the efficacy and safety of olopatadine and fexofenadine compared with placebo in Japanese cedar pollinosis using an environmental exposure unit.

Journal: Journal of investigational allergology & clinical immunology20090101

Title: Long-term effects of Panax ginseng on disposition of fexofenadine in rats in vivo.

Journal: The American journal of Chinese medicine20090101

Title: Bioequivalence of fexofenadine tablet formulations assessed in healthy Iranian volunteers.

Journal: Arzneimittel-Forschung20090101

Title: Mechanistic modeling of hepatic transport from cells to whole body: application to napsagatran and fexofenadine.

Journal: Molecular pharmaceutics20090101

Title: Efficacy of repeated pretreatment with olopatadine hydrochloride on rhinitis induced by intranasal instillation of toluene-2,4-diisocyanate in rats.

Journal: Pharmacology20090101

Title: Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast.

Journal: Drugs20090101

Title: Effects of fexofenadine on inflammatory mediators in nasal lavage fluid in intermittent allergic rhinitis.

Journal: Journal of investigational allergology & clinical immunology20090101

Title: Psoriasis vulgaris and digestive system disorders: is there a linkage?

Journal: Folia histochemica et cytobiologica20090101

Title: Involvement of intestinal uptake transporters in the absorption of azithromycin and clarithromycin in the rat.

Journal: Drug metabolism and disposition: the biological fate of chemicals20081201

Title: Design, data analysis, and simulation of in vitro drug transport kinetic experiments using a mechanistic in vitro model.

Journal: Drug metabolism and disposition: the biological fate of chemicals20081201

Title: Narrowband ultraviolet B phototherapy is beneficial in antihistamine-resistant symptomatic dermographism: a pilot study.

Journal: Journal of the American Academy of Dermatology20081101

Title: Potential benefit from an H1-receptor antagonist on postexercise syncope in the heat.

Journal: Medicine and science in sports and exercise20081101

Title: Validation of the use of nonnaive surgically catheterized rats for pharmacokinetics studies.

Journal: Journal of the American Association for Laboratory Animal Science : JAALAS20081101

Title: Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics: II. Ritonavir effects on CYP3A and P-glycoprotein activities.

Journal: Clinical pharmacology and therapeutics20081001

Title: Relative contribution of absorptive and secretory transporters to the intestinal absorption of fexofenadine in rats.

Journal: International journal of pharmaceutics20080901

Title: Probenecid, but not cystic fibrosis, alters the total and renal clearance of fexofenadine.

Journal: Journal of clinical pharmacology20080801

Title: Fexofenadine effects on cognitive performance in aviators at ground level and simulated altitude.

Journal: Aviation, space, and environmental medicine20080801

Title: A simple and rapid high performance liquid chromatographic method with fluorescence detection for the estimation of fexofenadine in rat plasma--application to preclinical pharmacokinetics.

Journal: Talanta20080715

Title: Evaluation of the antihistamine effects of olopatadine, cetirizine and fexofenadine during a 24 h period: a double-blind, randomized, crossover, placebo-controlled comparison in skin responses induced by histamine iontophoresis.

Journal: Archives of dermatological research20080701

Title: The effects of fexofenadine at steady-state on sleep architecture: a study using polysomnography in healthy Korean volunteers.

Journal: Expert opinion on pharmacotherapy20080701

Title: Involvement of multiple efflux transporters in hepatic disposition of fexofenadine.

Journal: Molecular pharmacology20080501

Title: Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers.

Journal: Drug metabolism and disposition: the biological fate of chemicals20080501

Title: The different effects of itraconazole on the pharmacokinetics of fexofenadine enantiomers.

Journal: British journal of clinical pharmacology20080501

Title: Modest effect of impaired P-glycoprotein on the plasma concentrations of fexofenadine, quinidine, and loperamide following oral administration in collies.

Journal: Drug metabolism and disposition: the biological fate of chemicals20080501

Title: Time-dependent inhibition of histamine-induced cutaneous responses by oral and intramuscular diphenhydramine and oral fexofenadine.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20080501

Title: Investigation of the inhibitory effects of various drugs on the hepatic uptake of fexofenadine in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals20080401

Title: Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.

Journal: Methods and findings in experimental and clinical pharmacology20080401

Title: Fexofenadine in pediatrics: oral tablet and suspension formulations.

Journal: Expert opinion on pharmacotherapy20080201

Title: Effect of Ginkgo biloba extract on lopinavir, midazolam and fexofenadine pharmacokinetics in healthy subjects.

Journal: Current medical research and opinion20080201

Title: Isolation and structure elucidation of photodegradation products of fexofenadine.

Journal: Journal of pharmaceutical and biomedical analysis20080122

Title: Development and validation of a rapid RP-HPLC method for the determination of cetirizine or fexofenadine with pseudoephedrine in binary pharmaceutical dosage forms.

Journal: Journal of pharmaceutical and biomedical analysis20080122

Title: Multidrug resistance-associated protein 2 is primarily responsible for the biliary excretion of fexofenadine in mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals20080101

Title: Fexofenadine downmodulates antigen-presenting ability of murine epidermal Langerhans cells.

Journal: Journal of dermatological science20080101

Title: Atopic cough-like cough hypersensitivity caused by active sensitization with protein fraction of Aspergillus restrictus strain A-17.

Journal: Pulmonary pharmacology & therapeutics20080101

Title: Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review.

Journal: Clinical pharmacokinetics20080101

Title: Non-interventional study comparing treatment satisfaction in patients treated with antihistamines.

Journal: Clinical drug investigation20080101

Title: Pharmacokinetics, safety and tolerability of an oral suspension of fexofenadine for children with allergic rhinitis.

Journal: Allergy and asthma proceedings20080101

Title: Comparative efficacy of levocetirizine, desloratidine and fexofenadine by histamine wheal suppression test.

Journal: Indian journal of dermatology, venereology and leprology20080101

Title: Loratadine provides early symptom control in seasonal allergic rhinitis.

Journal: Allergy and asthma proceedings20080101

Title: Visualization of first-pass drug metabolism of terfenadine by MALDI-imaging mass spectrometry.

Journal: Drug metabolism letters20080101

Title: Alternative and improved method for the simultaneous determination of fexofenadine and pseudoephedrine in their combined tablet formulation.

Journal: Journal of pharmaceutical and biomedical analysis20071221

Title: Antihistamine and sodium cromoglycate medication for food cold water exercise-induced anaphylaxis.

Journal: Allergy20071201

Title: [Linear dermatitis due to shiitake mushrooms].

Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete20071201

Title: Two cases of alopecia areata responsive to fexofenadine.

Journal: The Journal of dermatology20071201

Title: Safety and tolerability of fexofenadine hydrochloride, 15 and 30 mg, twice daily in children aged 6 months to 2 years with allergic rhinitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20071201

Title: Laser ablation electrospray ionization for atmospheric pressure, in vivo, and imaging mass spectrometry.

Journal: Analytical chemistry20071101

Title: Fexofenadine/cyclodextrin inclusion complexation: phase solubility, thermodynamic, physicochemical, and computational analysis.

Journal: Drug development and industrial pharmacy20071101

Title: Microdose clinical trial: quantitative determination of fexofenadine in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20071015

Title: Suppressive activity of fexofenadine hydrochloride on nitric oxide production in-vitro and in-vivo.

Journal: The Journal of pharmacy and pharmacology20071001

Title: Safety and tolerability of fexofenadine for the treatment of allergic rhinitis in children 2 to 5 years old.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20071001

Title: Formaldehyde-induced urticarial vasculitis.

Journal: The Australasian journal of dermatology20070801

Title: Combination therapy using fexofenadine, disodium cromoglycate, and a hypoallergenic amino acid-based formula induced remission in a patient with steroid-dependent, chronically active ulcerative colitis.

Journal: International journal of colorectal disease20070701

Title: Bioequivalence of two fexofenadine formulations in healthy human volunteers after single oral administration.

Journal: Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia20070601

Title: Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice.

Journal: Clinical pharmacology and therapeutics20070401

Title: Effect of oral ketoconazole on intestinal first-pass effect of midazolam and fexofenadine in cynomolgus monkeys.

Journal: Drug metabolism and disposition: the biological fate of chemicals20070301

Title: Intestinal drug transporter expression and the impact of grapefruit juice in humans.

Journal: Clinical pharmacology and therapeutics20070301

Title: Pharmacokinetics of fexofenadine enantiomers in healthy subjects.

Journal: Chirality20070301

Title: Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats.

Journal: Biological & pharmaceutical bulletin20070301

Title: Enhancing effect of surfactants on fexofenadine.HCl transport across the human nasal epithelial cell monolayer.

Journal: International journal of pharmaceutics20070207

Title: Quantification of fexofenadine in human plasma by liquid chromatography coupled to electrospray tandem mass spectrometry using mosapride as internal standard.

Journal: Biomedical chromatography : BMC20070201

Title: Simple and reliable HPLC analysis of fexofenadine hydrochloride in tablets and its application to dissolution studies.

Journal: Die Pharmazie20070201

Title: The effect of fexofenadine hydrochloride on productivity and quality of life in patients with chronic idiopathic urticaria.

Journal: Cutis20070201

Title: Determination of fexofenadine enantiomers in human plasma with high-performance liquid chromatography.

Journal: Journal of pharmaceutical and biomedical analysis20070117

Title: Inhibition of cytokine-induced expression of T-cell cytokines by antihistamines.

Journal: Journal of investigational allergology & clinical immunology20070101

Title: Efficacy of fexofenadine versus desloratadine in suppressing histamine-induced wheal and flare.

Journal: Allergy and asthma proceedings20070101

Title: Direct injection liquid chromatographic technique for simultaneous determination of two antihistaminic drugs and their main metabolites in serum.

Journal: Journal of AOAC International20070101

Title: Some pharmacokinetic aspects of the lipophilic terfenadine and zwitterionic fexofenadine in humans.

Journal: Drugs in R&D20070101

Title: The proarrhythmic antihistaminic drug terfenadine increases spontaneous calcium release in human atrial myocytes.

Journal: European journal of pharmacology20061228

Title: Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs.

Journal: European annals of allergy and clinical immunology20061201

Title: Lack of dose-dependent effects of itraconazole on the pharmacokinetic interaction with fexofenadine.

Journal: Drug metabolism and disposition: the biological fate of chemicals20061101

Title: Treatment of allergic rhinitis can improve blood pressure control.

Journal: Journal of human hypertension20061101

Title: New antihistamines: a critical view.

Journal: Jornal de pediatria20061101

Title: Ultrarush venom desensitization after systemic reactions during conventional venom immunotherapy.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20061101

Title: [Inhibition of histamine-induced wheel after a recommended single dose administration of 10 mg cetirizine, 5 mg desloratadine, 120 i 180 mg fexofenadine, 5 mg levocetirizine and 10 mg loratadine--a randomized, double-blind, placebo controlled trial].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego20061101

Title: [The effect of 5-days of cetirizine, desloratadine, fexofenadine 120 and 180 mg, levocetirizine, loratadine treatment on the histamine-induced skin reaction and skin blood flow--a randomized, double-blind, placebo controlled trial].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego20061101

Title: Involvement of ionotropic purinergic receptors in the histamine-induced enhancement of the cough reflex sensitivity in guinea pigs.

Journal: European journal of pharmacology20061010

Title: QT interval prolongation and beyond.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc20061001

Title: Onset of action of fexofenadine hydrochloride 60 mg/pseudoephedrine hydrochloride 120 mg in subjects aged 12 years with moderate to severe seasonal allergic rhinitis: a pooled analysis of two single-dose, randomized, double-blind, placebo-controlled allergen exposure unit studies.

Journal: Clinical therapeutics20061001

Title: Effects of single and multiple doses of itraconazole on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein.

Journal: British journal of clinical pharmacology20060901

Title: Altered oral bioavailability and pharmacokinetics of P-glycoprotein substrates by coadministration of biochanin A.

Journal: Journal of pharmaceutical sciences20060901

Title: Hepatobiliary disposition of a drug/metabolite pair: Comprehensive pharmacokinetic modeling in sandwich-cultured rat hepatocytes.

Journal: The Journal of pharmacology and experimental therapeutics20060801

Title: Facial thermography is a sensitive tool to determine antihistaminic activity: comparison of levocetirizine and fexofenadine.

Journal: British journal of clinical pharmacology20060801

Title: Alteration of fexofenadine disposition in the rat isolated perfused liver following injection of bacterial lipopolysaccharide.

Journal: Clinical and experimental pharmacology & physiology20060801

Title: Transporter-mediated intestinal absorption of fexofenadine in rats.

Journal: Drug metabolism and pharmacokinetics20060801

Title: A combined neurophysiological and behavioural study into the stimulating effects of fexofenadine on performance.

Journal: Journal of psychopharmacology (Oxford, England)20060701

Title: First-pass effects of verapamil on the intestinal absorption and liver disposition of fexofenadine in the porcine model.

Journal: Drug metabolism and disposition: the biological fate of chemicals20060701

Title: Stimulating effects of the antihistamine fexofenadine: testing the dopamine transporter hypothesis.

Journal: Psychopharmacology20060701

Title: Time-dependent interaction between lopinavir/ritonavir and fexofenadine.

Journal: Journal of clinical pharmacology20060701

Title: Allergy medication in Japanese volunteers: treatment effect of single doses on nocturnal sleep architecture and next day residual effects.

Journal: Current medical research and opinion20060701

Title: Efficacy and central nervous system impairment of newer-generation prescription antihistamines in seasonal allergic rhinitis.

Journal: Southern medical journal20060601

Title: Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid.

Journal: Drug metabolism and disposition: the biological fate of chemicals20060501

Title: Effect of P-glycoprotein on intestinal absorption and brain penetration of antiallergic agent bepotastine besilate.

Journal: Drug metabolism and disposition: the biological fate of chemicals20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: Once-daily immediate-release fexofenadine and sustained-release pseudoephedrine combination: a new treatment option for allergic rhinitis.

Journal: Expert opinion on pharmacotherapy20060501

Title: Effects of itraconazole and diltiazem on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein.

Journal: British journal of clinical pharmacology20060501

Title: Pustular exacerbation of psoriasis due to fexofenadine.

Journal: Clinical and experimental dermatology20060501

Title: Fexofenadine in horses: pharmacokinetics, pharmacodynamics and effect of ivermectin pretreatment.

Journal: Journal of veterinary pharmacology and therapeutics20060401

Title: Effect of pretreatment with fexofenadine on the safety of immunotherapy in patients with allergic rhinitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20060401

Title: The effect of short- and long-term administration of verapamil on the disposition of cytochrome P450 3A and P-glycoprotein substrates.

Journal: Clinical pharmacology and therapeutics20060301

Title: Efficacy of fexofenadine in the prophylactic control of cat allergen-induced allergic rhinitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20060201

Title: Effect of erythromycin on the absorption of fexofenadine in the jejunum, ileum and colon determined using local intubation in healthy volunteers.

Journal: International journal of clinical pharmacology and therapeutics20060201

Title: Fexofenadine, an H1-receptor antagonist, partially but rapidly inhibits the itch of contact dermatitis induced by diphenylcyclopropenone in patients with alopecia areata.

Journal: The Journal of dermatology20060201

Title: Differential effects of fexofenadine on arachidonic acid metabolism in cultured human monocytes.

Journal: Pharmacology20060101

Title: In vivo pharmacological characterisation of bilastine, a potent and selective histamine H1 receptor antagonist.

Journal: Drugs in R&D20060101

Title: Efficacy of desloratadine, 5 mg, compared with fexofenadine, 180 mg, in patients with symptomatic seasonal allergic rhinitis.

Journal: Allergy and asthma proceedings20060101

Title: Saliva secretion in patients with allergic rhinitis.

Journal: International archives of allergy and immunology20060101

Title: Marketing of a new non-sedating antihistamine (fexofenadine) puts an additional burden on healthcare system resources in Israel.

Journal: The European journal of general practice20060101

Title: Simultaneous quantification of fexofenadine and pseudoephedrine in human plasma by liquid chromatography/tandem mass spectrometry with electrospray ionization: method development, validation and application to a clinical study.

Journal: Rapid communications in mass spectrometry : RCM20060101

Title: New evidence of H1-receptor independent COX-2 inhibition by fexofenadine HCl in vitro.

Journal: Pharmacology20060101

Title: The effect of fexofenadine on pruritus in a mouse model (HR-ADf) of atopic dermatitis.

Journal: The Journal of international medical research20060101

Title: Selecting the optimal oral antihistamine for patients with allergic rhinitis.

Journal: Drugs20060101

Title: [Treatment of allergic rhinitis associated with hypothyroidism].

Journal: Vestnik otorinolaringologii20060101

Title: The methanol disolvate and the dihydrate of fexofenadine, an antihistamine drug.

Journal: Acta crystallographica. Section C, Crystal structure communications20051201

Title: The efficacy and safety of 30 mg fexofenadine HCl bid in pediatric patients with allergic rhinitis.

Journal: Asian Pacific journal of allergy and immunology20051201

Title: Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals20051001

Title: Effects of fexofenadine hydrochloride in a guinea pig model of antigen-induced rhinitis.

Journal: Pharmacology20051001

Title: Effects of fexofenadine and hydroxyzine on brake reaction time during car-driving with cellular phone use.

Journal: Human psychopharmacology20051001

Title: Transport of anti-allergic drugs across the passage cultured human nasal epithelial cell monolayer.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20051001

Title: Treatment of ear pain in pilots in flight.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20051001

Title: The various effects of four H1-antagonists on serum substance P levels in patients with atopic dermatitis.

Journal: The Journal of dermatology20051001

Title: [Wheat anaphylaxis enhanced by administration of acetylsalicylic acid or by exercise].

Journal: Arerugi = [Allergy]20051001

Title: Suppression of the histamine-induced wheal and flare response by fexofenadine HCl 60 mg twice daily, loratadine 10 mg once daily and placebo in healthy Japanese volunteers.

Journal: Current medical research and opinion20050901

Title: Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20050901

Title: Determination of fexofenadine in tablets by capillary electrophoresis in free solution and in solution with cyclodextrins as analyte carriers.

Journal: Drug development and industrial pharmacy20050901

Title: Histamine H1 receptor occupancy and pharmacodynamics of second generation H1-antihistamines.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]20050901

Title: Development and validation of dissolution tests for fexofenadine hydrochloride capsules and coated tablets.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques20050811

Title: Management of seasonal allergic rhinitis: comparative efficacy of the newer-generation prescription antihistamines.

Journal: Journal of the American Academy of Nurse Practitioners20050801

Title: Effect of itraconazole on the pharmacokinetics and pharmacodynamics of fexofenadine in relation to the MDR1 genetic polymorphism.

Journal: Clinical pharmacology and therapeutics20050801

Title: The advantages of the Ussing chamber in drug absorption studies.

Journal: Journal of biomolecular screening20050801

Title: Assessing the therapeutic benefits of antihistamines for the treatment of chronic idiopathic urticaria--a requirement for well-designed comparative clinical studies.

Journal: The Journal of dermatological treatment20050801

Title: P-glycoprotein plays a major role in the efflux of fexofenadine in the small intestine and blood-brain barrier, but only a limited role in its biliary excretion.

Journal: Drug metabolism and disposition: the biological fate of chemicals20050701

Title: Levocetirizine has a longer duration of action on improving total nasal symptoms score than fexofenadine after single administration.

Journal: British journal of clinical pharmacology20050701

Title: Once-daily fexofenadine treatment for chronic idiopathic urticaria: a multicenter, randomized, double-blind, placebo-controlled study.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20050601

Title: Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1).

Journal: British journal of clinical pharmacology20050501

Title: Single-dose and steady-state bioequivalence of fexofenadine and pseudoephedrine combination tablets compared with individual formulations in healthy adults.

Journal: Current medical research and opinion20050501

Title: Preferential downmodulation of certain chemokines by fexofenadine in human keratinocytes.

Journal: Journal of dermatological science20050401

Title: The efficacy of short-term administration of 3 antihistamines vs placebo under natural exposure to Japanese cedar pollen.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20050401

Title: H1 receptor-mediated vasodilatation contributes to postexercise hypotension.

Journal: The Journal of physiology20050301

Title: CYP3A and P-glycoprotein activity induction with St. John's Wort in healthy volunteers from 6 ethnic populations.

Journal: Journal of clinical pharmacology20050301

Title: Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: possible role of organic anion transporting polypeptides.

Journal: Clinical pharmacology and therapeutics20050301

Title: Effect of fruit juices on the oral bioavailability of fexofenadine in rats.

Journal: Journal of pharmaceutical sciences20050201

Title: Fexofenadine improves the quality of life and work productivity in Japanese patients with seasonal allergic rhinitis during the peak cedar pollinosis season.

Journal: International archives of allergy and immunology20050201

Title: Evaluation of first-pass cytochrome P4503A (CYP3A) and P-glycoprotein activities using alfentanil and fexofenadine in combination.

Journal: Journal of clinical pharmacology20050101

Title: Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics.

Journal: Clinical pharmacology and therapeutics20050101

Title: Minimal important difference (MID) of the Dermatology Life Quality Index (DLQI): results from patients with chronic idiopathic urticaria.

Journal: Health and quality of life outcomes20050101

Title: Comparative effects of fexofenadine and montelukast on allergen-induced wheal and flare.

Journal: Allergy and asthma proceedings20050101

Title: Capillary electrophoresis method for fexofenadine hydrochloride in capsules.

Journal: Journal of AOAC International20050101

Title: Comparative efficacy of cetirizine and fexofenadine for seasonal allergic rhinitis, 5-12 hours postdose, in the environmental exposure unit.

Journal: Allergy and asthma proceedings20050101

Title: The effect of fexofenadine on expression of intercellular adhesion molecule 1 and induction of apoptosis on peripheral eosinophils.

Journal: Allergy and asthma proceedings20050101

Title: The utility of mixed-effects covariate analysis in rapid selection of doses in pediatric subjects: a case study with fexofenadine hydrochloride.

Journal: Biopharmaceutics & drug disposition20041201

Title: Similar rapid onset of action and magnitude of effect of fexofenadine and cetirizine as assessed by inhibition of histamine-induced wheal-and-flare reaction.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20041201

Title: Suppressive activity of fexofenadine hydrochloride on metalloproteinase production from nasal fibroblasts in vitro.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology20041201

Title: Microbial oxidation of terfenadine and ebastine into fexofenadine and carebastine.

Journal: Bioorganic & medicinal chemistry letters20041101

Title: A variant 2677A allele of the MDR1 gene affects fexofenadine disposition.

Journal: Clinical pharmacology and therapeutics20041101

Title: Effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-induced wheal-and flare-response, sedation, and psychomotor performance.

Journal: Clinical and experimental dermatology20040901

Title: Venom immunotherapy: adverse reactions and treatment failure.

Journal: Current opinion in allergy and clinical immunology20040801

Title: Central effects of fexofenadine and cetirizine: measurement of psychomotor performance, subjective sleepiness, and brain histamine H1-receptor occupancy using 11C-doxepin positron emission tomography.

Journal: Journal of clinical pharmacology20040801

Title: Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans.

Journal: Fundamental & clinical pharmacology20040801

Title: Validation of the Dermatology Life Quality Index as an outcome measure for urticaria-related quality of life.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20040801

Title: Efficacy of azelastine nasal spray in seasonal allergic rhinitis patients who remain symptomatic after treatment with fexofenadine.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20040801

Title: A novel membrane sensor for histamine H1-receptor antagonist 'fexofenadine'.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry20040801

Title: Transport characteristics of fexofenadine in the Caco-2 cell model.

Journal: Pharmaceutical research20040801

Title: Determination of fexofenadine in human plasma using 96-well solid phase extraction and HPLC with tandem mass spectrometric detection.

Journal: Journal of pharmaceutical and biomedical analysis20040629

Title: Liquid chromatographic determination of fexofenadine in human plasma with fluorescence detection.

Journal: Journal of pharmaceutical and biomedical analysis20040629

Title: Effects of single or combined histamine H1-receptor and leukotriene CysLT1-receptor antagonism on nasal adenosine monophosphate challenge in persistent allergic rhinitis.

Journal: British journal of clinical pharmacology20040601

Title: Safety and efficacy of oral fexofenadine in children with seasonal allergic rhinitis--a pooled analysis of three studies.

Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology20040601

Title: Fexofenadine does not affect omeprazole pharmacokinetics: both are putative P-glycoprotein substrates.

Journal: Basic & clinical pharmacology & toxicology20040501

Title: Comparative efficacy of wheal-and-flare suppression among various non-sedating antihistamines and the pharmacologic insights to their efficacy.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet20040501

Title: Repeated dosing effects of mediator antagonists in inhaled corticosteroid-treated atopic asthmatic patients.

Journal: Chest20040401

Title: A placebo-controlled evaluation of butterbur and fexofenadine on objective and subjective outcomes in perennial allergic rhinitis.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology20040401

Title: Comparative effects of desloratadine, fexofenadine, and levocetirizine on nasal adenosine monophosphate challenge in patients with perennial allergic rhinitis.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology20040401

Title: Lack of association between fexofenadine and rhabdomyolysis.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists20040401

Title: Mizolastine and fexofenadine modulate cytokine pattern after nasal allergen challenge.

Journal: European annals of allergy and clinical immunology20040401

Title: Suppressive activity of fexofenadine hydrochloride on thymus- and activation-regulated chemokine production from human peripheral blood leukocytes in response to antigenic stimulation in vitro.

Journal: International archives of allergy and immunology20040301

Title: The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis.

Journal: International immunopharmacology20040301

Title: The effects of butterbur on the histamine and allergen cutaneous response.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20040201

Title: Assessing patient satisfaction with desloratadine after conversion from loratadine, fexofenadine, or cetirizine.

Journal: Managed care interface20040201

Title: Anti-inflammatory activity of H1-receptor antagonists: review of recent experimental research.

Journal: Current medical research and opinion20040101

Title: Comparative efficacy of cetirizine and fexofenadine in the treatment of chronic idiopathic urticaria.

Journal: The Journal of dermatological treatment20040101

Title: Comparison of the combinations of fexofenadine-pseudoephedrine and loratadine-montelukast in the treatment of seasonal allergic rhinitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20040101

Title: Randomized double-blind comparison of cetirizine and fexofenadine after pollen challenge in the Environmental Exposure Unit: duration of effect in subjects with seasonal allergic rhinitis.

Journal: Allergy and asthma proceedings20040101

Title: Onset of action for the relief of allergic rhinitis symptoms with second-generation antihistamines.

Journal: Allergy and asthma proceedings20040101

Title: Suppressive activity of fexofenadine hydrochloride on the production of eosinophil chemoattractants from human nasal fibroblasts in vitro.

Journal: Arzneimittel-Forschung20040101

Title: Development and validation of a liquid chromatographic method for fexofenadine hydrochloride in capsules.

Journal: Journal of AOAC International20040101

Title: Fexofenadine HCl 60 mg/ pseudoephedrine HCl 120 mg has a 60-minute onset of action in the treatment of seasonal allergic rhinitis symptoms, as assessed in an allergen exposure unit.

Journal: Allergy and asthma proceedings20040101

Title: [Serum sICAM-1 in patients suffering from allergic rhinitis treated with fexofenadine or fluticasone].

Journal: Pneumonologia i alergologia polska20040101

Title: Comparative study of acute effects of single doses of fexofenadine, olopatadine, d-chlorpheniramine and placebo on psychomotor function in healthy volunteers.

Journal: Human psychopharmacology20031201

Title: Multiple transport mechanisms involved in the intestinal absorption and first-pass extraction of fexofenadine.

Journal: Clinical pharmacology and therapeutics20031101

Title: A study comparing the inhibitory effects of single and repeated oral doses of ebastine and fexofenadine against histamine-induced skin reactivity.

Journal: International archives of allergy and immunology20031101

Title: Effect of the second-generation antihistamine, fexofenadine, on cough reflex sensitivity and pulmonary function.

Journal: British journal of clinical pharmacology20031101

Title: Mite-antigen induced immediate reactions in atopic dermatitis are inhibited by daily administration of fexofenadine.

Journal: The Journal of dermatology20031101

Title: Efficacy and safety profile of fexofenadine HCl: a unique therapeutic option in H1-receptor antagonist treatment.

Journal: The Journal of allergy and clinical immunology20031001

Title: Effects of fexofenadine and other antihistamines on components of the allergic response: adhesion molecules.

Journal: The Journal of allergy and clinical immunology20031001

Title: Effects of fexofenadine on T-cell function in a murine model of allergen-induced airway inflammation and hyperresponsiveness.

Journal: The Journal of allergy and clinical immunology20031001

Title: Is 3-mm less drowsiness important?

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20031001

Title: Fexofenadine hydrochloride, 180 mg, exhibits equivalent efficacy to cetirizine, 10 mg, with less drowsiness in patients with moderate-to-severe seasonal allergic rhinitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20031001

Title: Omalizumab, an anti-IgE antibody, in the treatment of adults and adolescents with perennial allergic rhinitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20030801

Title: The effects of fexofenadine on reaction time, decision-making, and driver behavior.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20030801

Title: Randomized, double-masked comparison of olopatadine ophthalmic solution, mometasone furoate monohydrate nasal spray, and fexofenadine hydrochloride tablets using the conjunctival and nasal allergen challenge models.

Journal: Clinical therapeutics20030801

Title: Herbal supplements and skin testing: the lack of effect of commonly used herbal supplements on histamine skin prick testing.

Journal: Allergy20030601

Title: Supplementation of fexofenadine therapy with nedocromil sodium 2% ophthalmic solution to treat ocular symptoms of seasonal allergic conjunctivitis.

Journal: Clinical & experimental ophthalmology20030601

Title: H1-antihistaminic activity of cetirizine and fexofenadine in allergic children.

Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology20030601

Title: Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study.

Journal: The British journal of dermatology20030601

Title: Relative potency of fexofenadine HCl 180 mg, loratadine 10 mg, and placebo using a skin test model of wheal-and-flare suppression.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20030601

Title: [Clinical aspects of anti-inflammatory action of antihistamines].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego20030601

Title: Effects of fexofenadine, diphenhydramine, and placebo on performance of the test of variables of attention (TOVA).

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20030501

Title: A single-center, randomized, double-blind, placebo-controlled, crossover investigation of the effects of fexofenadine hydrochloride 180 mg alone and with alcohol, with hydroxyzine hydrochloride 50 mg as a positive internal control, on aspects of cognitive and psychomotor function related to driving a car.

Journal: Clinical therapeutics20030501

Title: Fexofenadine is efficacious and safe in children (aged 6-11 years) with seasonal allergic rhinitis.

Journal: The Journal of allergy and clinical immunology20030401

Title: The effects of acute doses of fexofenadine, promethazine, and placebo on cognitive and psychomotor function in healthy Japanese volunteers.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20030401

Title: [H1 histamine antagonists].

Journal: Revue medicale de Bruxelles20030401

Title: Decongestant effects of antihistamines: a class effect?

Journal: The Journal of allergy and clinical immunology20030301

Title: Solar urticaria induced by infrared radiation.

Journal: Clinical and experimental dermatology20030301

Title: Effect of fexofenadine hydrochloride on cedar pollinosis.

Journal: Auris, nasus, larynx20030201

Title: Failure of cetirizine and fexofenadine to prevent motion sickness.

Journal: The Annals of pharmacotherapy20030201

Title: The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique.

Journal: British journal of clinical pharmacology20030201

Title: Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.

Journal: The Journal of allergy and clinical immunology20030201

Title: The effects of single-dose fexofenadine, diphenhydramine, and placebo on cognitive performance in flight personnel.

Journal: Aviation, space, and environmental medicine20030201

Title: Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects.

Journal: Clinical pharmacology and therapeutics20030101

Title: Internal standard signal suppression by co-eluting analyte in isotope dilution LC-ESI-MS.

Journal: The Analyst20030101

Title: [Effect of fexofenadine--selective antagonist of histamine receptor (H1) on histamine-induced bronchoconstriction].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego20030101

Title: Assessing satisfaction with desloratadine and fexofenadine in allergy patients who report dissatisfaction with loratadine.

Journal: BMC family practice20030101

Title: Roles of histamine in regulation of arousal and cognition: functional neuroimaging of histamine H1 receptors in human brain.

Journal: Life sciences20021220

Title: Inhibitory effects of oral prednisolone and fexofenadine on skin responses by prick tests with histamine and compound 48/80.

Journal: Journal of dermatological science20021201

Title: Facial swelling and eosinophilia in a 44-year-old woman.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20021201

Title: Effects of fexofenadine on the early response to nasal allergen challenge.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20021201

Title: Effect of fexofenadine, a mast cell blocker, in infertile men with significantly increased testicular mast cells.

Journal: Asian journal of andrology20021201

Title: The antihistamine fexofenadine does not affect I(Kr) currents in a case report of drug-induced cardiac arrhythmia.

Journal: British journal of pharmacology20021101

Title: Fexofenadine transport in Caco-2 cells: inhibition with verapamil and ritonavir.

Journal: Journal of clinical pharmacology20021101

Title: Clinical pharmacology of H1-antihistamines in the skin.

Journal: The Journal of allergy and clinical immunology20021101

Title: Effects of fexofenadine and desloratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology20021001

Title: Review of fexofenadine in the treatment of chronic idiopathic urticaria.

Journal: International journal of dermatology20021001

Title: The use of handheld computers in clinical trials.

Journal: Controlled clinical trials20021001

Title: Simultaneous determination of fexofenadine and its related compounds by HPLC.

Journal: Journal of pharmaceutical and biomedical analysis20020720

Title: Chronic urticaria and angioedema.

Journal: The New England journal of medicine20020718

Title: Role of lung inflammatory mediators as a cause of exercise-induced arterial hypoxemia in young athletes.

Journal: Journal of applied physiology (Bethesda, Md. : 1985)20020701

Title: Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness.

Journal: The Journal of allergy and clinical immunology20020701

Title: Onset of action, efficacy, and safety of fexofenadine 60 mg/pseudoephedrine 120 mg versus placebo in the Atlanta allergen exposure unit.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20020701

Title: Comparison of the efficacy of combined fluticasone propionate and olopatadine versus combined fluticasone propionate and fexofenadine for the treatment of allergic rhinoconjunctivitis induced by conjunctival allergen challenge.

Journal: Clinical therapeutics20020701

Title: In vivo anti-inflammatory effects of fexofenadine in chronic idiopathic urticaria.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV20020701

Title: Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block.

Journal: Circulation20020618

Title: Are herbal products dietary supplements or drugs? An important question for public safety.

Journal: Clinical pharmacology and therapeutics20020601

Title: Effect of St John's wort on the pharmacokinetics of fexofenadine.

Journal: Clinical pharmacology and therapeutics20020601

Title: MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine.

Journal: British journal of clinical pharmacology20020501

Title: Evaluation of cytokines in nasal secretions after nasal antigen challenge: lack of influence of antihistamines.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20020501

Title: [Hay fever and asthma. Many of your patients have both].

Journal: MMW Fortschritte der Medizin20020425

Title: [Chronic idiopathic urticaria: effectiveness of fexofenadine. A double-blind, placebo controlled study with 21 patients].

Journal: Praxis20020410

Title: A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20020201

Title: Are antihistamines useful in managing asthma?

Journal: Current opinion in allergy and clinical immunology20020201

Title: Determination of fexofenadine in human plasma and urine by liquid chromatography-mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20020125

Title: Induction of multidrug resistance-1 and cytochrome P450 mRNAs in human mononuclear cells by rifampin.

Journal: Drug metabolism and disposition: the biological fate of chemicals20020101

Title: Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.

Journal: Clinical pharmacology and therapeutics20020101

Title: Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine.

Journal: Clinical pharmacokinetics20020101

Title: [Comparative antihistamine and anti-allergic effects of various antihistamine preparations].

Journal: Terapevticheskii arkhiv20020101

Title: A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology20020101

Title: An evaluation of the effects of high-dose fexofenadine on the central nervous system: a double-blind, placebo-controlled study in healthy volunteers.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology20020101

Title: Liquid chromatography/tandem mass spectrometric bioanalysis using normal-phase columns with aqueous/organic mobile phases - a novel approach of eliminating evaporation and reconstitution steps in 96-well SPE.

Journal: Rapid communications in mass spectrometry : RCM20020101

Title: The use of antihistamines in safety-critical jobs: a meeting report.

Journal: Current medical research and opinion20020101

Title: Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state.

Journal: Drugs under experimental and clinical research20020101

Title: Fexofenadine reduces nasal congestion in perennial allergic rhinitis.

Journal: Allergy20011101

Title: The costs of nonsedating antihistamine therapy for allergic rhinitis in managed care: an updated analysis.

Journal: The American journal of managed care20011001

Title: Ugly wait at the counter. Insurer pushes to make allergy drugs nonprescription.

Journal: Modern healthcare20010806

Title: Identification of functionally variant MDR1 alleles among European Americans and African Americans.

Journal: Clinical pharmacology and therapeutics20010801

Title: Safety of fexofenadine in children treated for seasonal allergic rhinitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20010701

Title: Evaluation of the safety of fexofenadine from experience gained in general practice use in England in 1997.

Journal: European journal of clinical pharmacology20010701

Title: [Seasonal allergic rhinitis. Nasal obstruction can also beh improved].

Journal: MMW Fortschritte der Medizin20010503

Title: Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol.

Journal: American journal of respiratory and critical care medicine20010501

Title: Controlled comparison of the efficacy and safety of cetirizine 10 mg o.d. and fexofenadine 120 mg o.d. in reducing symptoms of seasonal allergic rhinitis.

Journal: International archives of allergy and immunology20010501

Title: A descriptive analysis of the use and cost of new-generation antihistamines in the treatment of allergic rhinitis: a retrospective database analysis.

Journal: The American journal of managed care20010501

Title: Newer antihistamines.

Journal: The Medical letter on drugs and therapeutics20010430

Title: Uptake and efflux of the peptidic delta-opioid receptor agonist.

Journal: Neuroscience letters20010406

Title: Twenty-four hours of activity of cetirizine and fexofenadine in the skin.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20010401

Title: Histamine induces exocytosis and IL-6 production from human lung macrophages through interaction with H1 receptors.

Journal: Journal of immunology (Baltimore, Md. : 1950)20010315

Title: Skin concentrations of H1-receptor antagonists.

Journal: The Journal of allergy and clinical immunology20010301

Title: The effect of rifampin administration on the disposition of fexofenadine.

Journal: Clinical pharmacology and therapeutics20010301

Title: Fexofenadine hydrochloride--a new anti-histaminic drug.

Journal: The Israel Medical Association journal : IMAJ20010301

Title: Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: a randomized, placebo-controlled, parallel-group study.

Journal: Clinical therapeutics20010301

Title: Fixed solar urticaria to visible light successfully treated with fexofenadine.

Journal: Photodermatology, photoimmunology & photomedicine20010201

Title: Multicenter study of the efficacy and safety of fexofenadine 60 mg. twice daily in 108 Thai patients with chronic idiopathic urticaria.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet20010201

Title: Comparison of montelukast and fexofenadine for chronic idiopathic urticaria.

Journal: Archives of dermatology20010101

Title: Suppression of the early and late cutaneous allergic responses using fexofenadine and montelukast.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20010101

Title: Histamine-induced activation of human lung macrophages.

Journal: International archives of allergy and immunology20010101

Title: [The effect of second generation histamine antagonists on the heart].

Journal: Pneumonologia i alergologia polska20010101

Title: [Efficacy and safety of fexofenadine and cetirizine in the treatment of allergic rhinitis].

Journal: Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)20010101

Title: Fexofenadine HCl is safe and effective for treatment of chronic idiopathic urticaria.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20000501

Title: Sedation with 'non-sedating' antihistamines: four prescription-event monitoring studies in general practice.

Journal: BMJ (Clinical research ed.)20000429

Title: Severe cardiac arrhythmia on fexofenadine?

Journal: Prescrire international20000201

Title: Fexofenadine and prolonged QT intervals.

Journal: Nursing19990901

Title: QT lengthening and life-threatening arrhythmias associated with fexofenadine.

Journal: Lancet (London, England)19990320

Title: Fexofenadine.

Journal: Drugs19980201

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