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284028-90-6,MFCD08703132
Catalog No.:AA007KLQ

284028-90-6 | 7,8-Dihydro-2-methyl-1h-thiopyrano[4,3-d]pyrimidin-4(5h)-one

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1mg
≥98%
in stock  
$46.00   $32.00
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5mg
≥98%
in stock  
$106.00   $74.00
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10mg
≥98%
in stock  
$175.00   $122.00
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25mg
≥98%
in stock  
$329.00   $230.00
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50mg
98%(HPLC)
in stock  
$588.00   $412.00
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100mg
98%(HPLC)
in stock  
$852.00   $597.00
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA007KLQ
Chemical Name:
7,8-Dihydro-2-methyl-1h-thiopyrano[4,3-d]pyrimidin-4(5h)-one
CAS Number:
284028-90-6
Molecular Formula:
C8H10N2OS
Molecular Weight:
182.2428
MDL Number:
MFCD08703132
SMILES:
O=c1nc(C)[nH]c2c1CSCC2
Properties
Computed Properties
 
Complexity:
293  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
XLogP3:
-0.2  

Literature

Title: A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 [2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20050201

Title: Nakajima H, et, al. A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 -methyl-3,5,7,8-tetrahydrothiopyrano,3-d-pyrimidine-4-one: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats. J Pharmacol Exp Ther. 2005 Feb;312(2):472-81.

Title: Xu Z, et, al. Endonuclease G does not play an obligatory role in poly(ADP-ribose) polymerase-dependent cell death after transient focal cerebral ischemia. Am J Physiol Regul Integr Comp Physiol. 2010 Jul;299(1):R215-21.

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Tags:284028-90-6 Molecular Formula|284028-90-6 MDL|284028-90-6 SMILES|284028-90-6 7,8-Dihydro-2-methyl-1h-thiopyrano[4,3-d]pyrimidin-4(5h)-one