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172922-91-7,MFCD09879259
Catalog No.:AA007VKI

172922-91-7 | 5,11-Dihydroindolo[3,2-b]carbazole-6-carbaldehyde

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$163.00   $114.00
- +
5mg
≥95%
in stock  
$268.00   $188.00
- +
10mg
≥95%
in stock  
$375.00   $263.00
- +
25mg
≥95%
in stock  
$675.00   $473.00
- +
100mg
97%
in stock  
$710.00   $497.00
- +
250mg
97%
in stock  
$1,208.00   $846.00
- +
1g
97%
in stock  
$3,004.00 $2,103.00
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA007VKI
Chemical Name:
5,11-Dihydroindolo[3,2-b]carbazole-6-carbaldehyde
CAS Number:
172922-91-7
Molecular Formula:
C19H12N2O
Molecular Weight:
284.3114
MDL Number:
MFCD09879259
SMILES:
O=Cc1c2[nH]c3c(c2cc2c1c1ccccc1[nH]2)cccc3
Properties
Computed Properties
 
Complexity:
453  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
4.3  

Downstream Synthesis Route

[1]Tholander,Joakim;Bergman,Jan[TetrahedronLetters,1998,vol.39,#12,p.1619-1622]

204455-46-9    6336-32-9   
6-Formylindolo-(3,2-b)-carbazole 

[1]Tetrahedron,1999,vol.55,p.6243-6260

[1]Tholander,Joakim;Bergman,Jan[Tetrahedron,1999,vol.55,#19,p.6243-6260]

[1]Wahlstroem,Niklas;Romero,Ivan;Bergman,Jan[EuropeanJournalofOrganicChemistry,2004,#12,p.2593-2602]

[2]Sekine,Daisuke;Okeda,Shota;Hosokawa,Seijiro[ChemistryLetters,2014,vol.43,#12,p.1932-1934]

[1]Wahlstroem,Niklas;Romero,Ivan;Bergman,Jan[EuropeanJournalofOrganicChemistry,2004,#12,p.2593-2602]

Literature

Title: Mohammadi-Bardbori A, et al. The highly bioactive molecule and signal substance 6-formylindolo,2-bcarbazole (FICZ) plays bi-functional roles in cell growth and apoptosis in vitro. Arch Toxicol. 2017 Mar 13

Title: Farmahin R, et al. Time-dependent transcriptomic and biochemical responses of 6-formylindolo,2-bcarbazole (FICZ) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) are explained by AHR activation time. Biochem Pharmacol. 2016 Sep 1;115:134-43

Title: Smith BW, et al. Genome Editing of the CYP1A1 Locus in iPSCs as a Platform to Map AHR Expression throughout Human Development. Stem Cells Int. 2016;2016:2574152.

Title: Wincent E, et al. Biological effects of 6-formylindolo,2-bcarbazole (FICZ) in vivo are enhanced by loss of CYP1A function in an Ahr2-dependent manner. Biochem Pharmacol. 2016 Jun 15;110-111:117-29.

Title: N A Davarinos, et al. Aryl Hydrocarbon Receptor Imported Into the Nucleus Following Ligand Binding Is Rapidly Degraded via the Cytosplasmic Proteasome Following Nuclear Export. J Biol Chem. 1999 Oct 1;274(40):28708-15.

Title: Riccardo Sibilano, et al. The Aryl Hydrocarbon Receptor Modulates Acute and Late Mast Cell Responses. J Immunol. 2012 Jul 1;189(1):120-7.

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SDS
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Tags:172922-91-7 Molecular Formula|172922-91-7 MDL|172922-91-7 SMILES|172922-91-7 5,11-Dihydroindolo[3,2-b]carbazole-6-carbaldehyde
Catalog No.: AA007VKI
172922-91-7,MFCD09879259
172922-91-7 | 5,11-Dihydroindolo[3,2-b]carbazole-6-carbaldehyde
Pack Size： 1mg
Purity： ≥95%
in stock
$163.00 $114.00
Pack Size： 5mg
Purity： ≥95%
in stock
$268.00 $188.00
Pack Size： 10mg
Purity： ≥95%
in stock
$375.00 $263.00
Pack Size： 25mg
Purity： ≥95%
in stock
$675.00 $473.00
Pack Size： 100mg
Purity： 97%
in stock
$710.00 $497.00
Pack Size： 250mg
Purity： 97%
in stock
$1,208.00 $846.00
Pack Size： 1g
Purity： 97%
in stock
$3,004.00 $2,103.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA007VKI
Chemical Name: 5,11-Dihydroindolo[3,2-b]carbazole-6-carbaldehyde
CAS Number: 172922-91-7
Molecular Formula: C19H12N2O
Molecular Weight: 284.3114
MDL Number: MFCD09879259
SMILES: O=Cc1c2[nH]c3c(c2cc2c1c1ccccc1[nH]2)cccc3
Properties
Complexity: 453  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 22  
Hydrogen Bond Acceptor Count: 1  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 1  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 4.3  
Downstream Synthesis Route
204455-46-9    172922-91-7 

[1]Tholander,Joakim;Bergman,Jan[TetrahedronLetters,1998,vol.39,#12,p.1619-1622]

204455-46-9    6336-32-9   
6-Formylindolo-(3,2-b)-carbazole 

[1]Tetrahedron,1999,vol.55,p.6243-6260

229020-82-0    172922-91-7 

[1]Tholander,Joakim;Bergman,Jan[Tetrahedron,1999,vol.55,#19,p.6243-6260]

1432053-78-5    172922-91-7 

[1]Wahlstroem,Niklas;Romero,Ivan;Bergman,Jan[EuropeanJournalofOrganicChemistry,2004,#12,p.2593-2602]

[2]Sekine,Daisuke;Okeda,Shota;Hosokawa,Seijiro[ChemistryLetters,2014,vol.43,#12,p.1932-1934]

229020-86-4    172922-91-7 

[1]Wahlstroem,Niklas;Romero,Ivan;Bergman,Jan[EuropeanJournalofOrganicChemistry,2004,#12,p.2593-2602]

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