Name: Name:GRGDNP
Brand: AABLOCKS
SKU: AA008RPG
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA008RPG

Chemical Name: GRGDNP

CAS Number: 114681-65-1

Molecular Formula: C23H38N10O10

Molecular Weight: 614.6088

MDL Number: MFCD00153556

SMILES: NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)O)CC(=O)N)CC(=O)O)CCCNC(=N)N

Properties

Complexity: 1110

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 4

Heavy Atom Count: 43

Hydrogen Bond Acceptor Count: 12

Hydrogen Bond Donor Count: 10

Rotatable Bond Count: 18

XLogP3: -8.4

Literature fold

Title: Induction of non-small cell lung carcinoma apoptosis using soluble RGD-TRAIL by targeting the integrin receptor of tumor cells.

Journal: Molecular medicine reports20121201

Title: Mechanotransduction by integrin is essential for IL-6 secretion from endothelial cells in response to uniaxial continuous stretch.

Journal: American journal of physiology. Cell physiology20050501

Title: Inhibition of the adherence of T-lymphocytes to epithelial cells by a cyclic peptide derived from inserted domain of lymphocyte function-associated antigen-1.

Journal: Inflammation20010601

Title: Pathogenetic role of Arg-Gly-Asp-recognizing integrins in acute renal failure. off.

Journal: Proceedings of the National Academy of Sciences of the United States of America19930615

Title: Ruoslahti, E., and Öbrink, B. Common principles in cell adhesion Experimental Cell Research 227, 1-11 (1996).

Title: Meredith JE Jr, et al. Integrins, adhesion and apoptosis. Trends Cell Biol. 1997 Apr;7(4):146-50.

Title: Yang W, et al. Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1. J Biol Chem. 1999 Mar 26;274(13):8524-30.

114681-65-1 | GRGDNP