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1038915-64-8,MFCD20502397
Catalog No.:AA008TFB

1038915-64-8 | MK-4827 hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
98%
in stock  
$234.00   $164.00
- +
50mg
98%
in stock  
$375.00   $263.00
- +
100mg
98%
in stock  
$552.00   $387.00
- +
500mg
98%
in stock  
$2,284.00   $1,599.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA008TFB
Chemical Name:
MK-4827 hydrochloride
CAS Number:
1038915-64-8
Molecular Formula:
C19H21ClN4O
Molecular Weight:
356.8492
MDL Number:
MFCD20502397
SMILES:
NC(=O)c1cccc2c1nn(c2)c1ccc(cc1)[C@@H]1CCCNC1.Cl
Properties

Literature

Title: Jones P, et al. Discovery of 2-{4-[(3S)-piperidin-3-ylphenyl}-2H-indazole-7-carboxamide (MK-4827): a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors. J Med Chem. 2009 Nov 26;52(22):7170-85.

Title: Bridges KA, et al. Niraparib (MK-4827), a novel poly(ADP-Ribose) polymerase inhibitor, radiosensitizes human lung and breast cancer cells. Oncotarget. 2014 Jul 15;5(13):5076-86.

Title: Wang L, et al. MK-4827, a PARP-1/-2 inhibitor, strongly enhances response of human lung and breast cancer xenografts to radiation. Invest New Drugs. 2012 Dec;30(6):2113-20.

Title: Mirza MR, et al. Niraparib Maintenance Therapy in Platinum-Sensitive, Recurrent Ovarian Cancer. N Engl J Med. 2016 Dec 1;375(22):2154-2164.

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SDS
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Tags:1038915-64-8 Molecular Formula|1038915-64-8 MDL|1038915-64-8 SMILES|1038915-64-8 MK-4827 hydrochloride
Catalog No.: AA008TFB
1038915-64-8,MFCD20502397
1038915-64-8 | MK-4827 hydrochloride
Pack Size： 10mg
Purity： 98%
in stock
$234.00 $164.00
Pack Size： 50mg
Purity： 98%
in stock
$375.00 $263.00
Pack Size： 100mg
Purity： 98%
in stock
$552.00 $387.00
Pack Size： 500mg
Purity： 98%
in stock
$2,284.00 $1,599.00
Quantity
- +
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bulk Quotation Request
Technical Information
Catalog Number: AA008TFB
Chemical Name: MK-4827 hydrochloride
CAS Number: 1038915-64-8
Molecular Formula: C19H21ClN4O
Molecular Weight: 356.8492
MDL Number: MFCD20502397
SMILES: NC(=O)c1cccc2c1nn(c2)c1ccc(cc1)[C@@H]1CCCNC1.Cl
Properties
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