[1]CurrentPatentAssignee:MERCK&COINC-US2008/132542,2008,A1Locationinpatent:Page/Pagecolumn25
[1]Oballa,RenataM.;Belair,Liette;Black,W.Cameron;Bleasby,Kelly;Chan,ChiChung;Desroches,Carole;Du,Xiaobing;Gordon,Robert;Guay,Jocelyne;Guiral,Sebastien;Hafey,MichaelJ.;Hamelin,Emelie;Huang,Zheng;Kennedy,Brian;Lachance,Nicolas;Landry,France;Li,ChunSing;Mancini,Joseph;Normandin,Denis;Pocai,Alessandro;Powell,DavidA.;Ramtohul,YeemanK.;Skorey,Kathryn;Sørensen,Dan;Sturkenboom,Wayne;Styhler,Angela;Waddleton,DeenaM.;Wang,Hao;Wong,Simon;Xu,Lijing;Zhang,Lei[JournalofMedicinalChemistry,2011,vol.54,#14,p.5082-5096]
[1]Oballa,RenataM.;Belair,Liette;Black,W.Cameron;Bleasby,Kelly;Chan,ChiChung;Desroches,Carole;Du,Xiaobing;Gordon,Robert;Guay,Jocelyne;Guiral,Sebastien;Hafey,MichaelJ.;Hamelin,Emelie;Huang,Zheng;Kennedy,Brian;Lachance,Nicolas;Landry,France;Li,ChunSing;Mancini,Joseph;Normandin,Denis;Pocai,Alessandro;Powell,DavidA.;Ramtohul,YeemanK.;Skorey,Kathryn;Sørensen,Dan;Sturkenboom,Wayne;Styhler,Angela;Waddleton,DeenaM.;Wang,Hao;Wong,Simon;Xu,Lijing;Zhang,Lei[JournalofMedicinalChemistry,2011,vol.54,#14,p.5082-5096]
[1]Oballa,RenataM.;Belair,Liette;Black,W.Cameron;Bleasby,Kelly;Chan,ChiChung;Desroches,Carole;Du,Xiaobing;Gordon,Robert;Guay,Jocelyne;Guiral,Sebastien;Hafey,MichaelJ.;Hamelin,Emelie;Huang,Zheng;Kennedy,Brian;Lachance,Nicolas;Landry,France;Li,ChunSing;Mancini,Joseph;Normandin,Denis;Pocai,Alessandro;Powell,DavidA.;Ramtohul,YeemanK.;Skorey,Kathryn;Sørensen,Dan;Sturkenboom,Wayne;Styhler,Angela;Waddleton,DeenaM.;Wang,Hao;Wong,Simon;Xu,Lijing;Zhang,Lei[JournalofMedicinalChemistry,2011,vol.54,#14,p.5082-5096]
[1]Oballa,RenataM.;Belair,Liette;Black,W.Cameron;Bleasby,Kelly;Chan,ChiChung;Desroches,Carole;Du,Xiaobing;Gordon,Robert;Guay,Jocelyne;Guiral,Sebastien;Hafey,MichaelJ.;Hamelin,Emelie;Huang,Zheng;Kennedy,Brian;Lachance,Nicolas;Landry,France;Li,ChunSing;Mancini,Joseph;Normandin,Denis;Pocai,Alessandro;Powell,DavidA.;Ramtohul,YeemanK.;Skorey,Kathryn;Sørensen,Dan;Sturkenboom,Wayne;Styhler,Angela;Waddleton,DeenaM.;Wang,Hao;Wong,Simon;Xu,Lijing;Zhang,Lei[JournalofMedicinalChemistry,2011,vol.54,#14,p.5082-5096]
Title: Discovery of potent and liver-selective stearoyl-CoA desaturase (SCD) inhibitors in an acyclic linker series.
Journal: Bioorganic & medicinal chemistry letters 20120101
Title: Plasma-based approach to measure target engagement for liver-targeting stearoyl-CoA desaturase 1 inhibitors.
Journal: Journal of lipid research 20110801
Title: Development of a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor (MK-8245) to establish a therapeutic window for the treatment of diabetes and dyslipidemia.
Journal: Journal of medicinal chemistry 20110728
Title: Oballa RM, et al. Development of a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor (MK-8245) to establish a therapeutic window for the treatment of diabetes and dyslipidemia.J Med Chem. 2011 Jul 28;54(14):5082-96. Epub 2011 Jun 28.
