Home Other Building Blocks 1375465-09-0
1375465-09-0,MFCD26142654
Catalog No.:AA009C7T

1375465-09-0 | Cnx-2006

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$53.00   $37.00
- +
5mg
in stock  
$227.00   $159.00
- +
10mg
≥98%
in stock  
$405.00   $283.00
- +
25mg
in stock  
$599.00   $419.00
- +
500mg
98% by HPLC
in stock  
$7,722.00   $5,405.00
- +
1000mg
98% by HPLC
in stock  
$12,318.00   $8,623.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA009C7T
Chemical Name:
Cnx-2006
CAS Number:
1375465-09-0
Molecular Formula:
C26H27F4N7O2
Molecular Weight:
545.5319
MDL Number:
MFCD26142654
SMILES:
FCCN1CC(C1)Nc1ccc(c(c1)OC)Nc1ncc(c(n1)Nc1cccc(c1)NC(=O)C=C)C(F)(F)F
Properties
Computed Properties
 
Complexity:
801  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
39  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
11  
XLogP3:
4.8  

Literature

Title: Galvani E, et al. Abstract 3244: Role of epithelial-mesenchymal transition (EMT) in sensitivity to CNX-2006, a novel mutant-selective EGFR inhibitor which overcomes in vitro T790M-mediated resistance in NSCLC. CNX-2006, a novel mutant-selective EGFR inhibitor which overcomes in vitro T790M-mediated resistance in NSCLC. [abstract In: Proceedings of the 104th Annual Meeting of the American Association for Cancer Research; 2013 Apr 6-10; Ishington, DC. Philadelphia (PA): AACR; Cancer Res 2013;73(8 Suppl):Abstract nr 3244. doi:10.1158/1538-7445.AM2013-3244

Title: Ohashi K, et al. Abstract 2101A: CNX-2006, a novel irreversible epidermal growth factor receptor (EGFR) inhibitor, selectively inhibits EGFR T790M and fails to induce T790M-mediated resistance in vitro. [abstract In: Proceedings of the 104th Annual Meeting of the American Association for Cancer Research; 2013 Apr 6-10; Ishington, DC. Philadelphia (PA): AACR; Cancer Res 2013;73(8 Suppl):Abstract nr 2101A. doi:10.1158/1538-7445.AM2013-2101A

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 1375465-09-0
Tags:1375465-09-0 Molecular Formula|1375465-09-0 MDL|1375465-09-0 SMILES|1375465-09-0 Cnx-2006