Name: Name:Fmoc-Val-Cit-PAB-MMAE
Brand: AABLOCKS
SKU: AA009CJP
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA009CJP

Chemical Name: Fmoc-Val-Cit-PAB-MMAE

CAS Number: 1350456-56-2

Molecular Formula: C73H104N10O14

Molecular Weight: 1345.6655

MDL Number: MFCD30377196

SMILES: CC[C@@H]([C@H](N(C(=O)[C@H](C(C)C)NC(=O)[C@@H](N(C(=O)OCc1ccc(cc1)NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)OCC1c2ccccc2c2c1cccc2)CCCNC(=O)N)C)C(C)C)C)[C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@H](C(=O)N[C@@H]([C@H](c1ccccc1)O)C)C)OC)OC)C

Properties

Complexity: 2530

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 2

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 97

Hydrogen Bond Acceptor Count: 14

Hydrogen Bond Donor Count: 8

Isotope Atom Count: 0

Rotatable Bond Count: 36

Undefined Atom Stereocenter Count: 10

Undefined Bond Stereocenter Count: 0

XLogP3: 8.1

Downstream Synthesis Route

1350456-56-2

644981-35-1

[1]Tang,Feng;Yang,Yang;Tang,Yubo;Tang,Shuai;Yang,Liyun;Sun,Bingyang;Jiang,Bofeng;Dong,Jinhua;Liu,Hong;Huang,Min;Geng,Mei-Yu;Huang,Wei[OrganicandBiomolecularChemistry,2016,vol.14,#40,p.9501-9518]

[2]CurrentPatentAssignee:REMEGEN-US2022/72137,2022,A1Locationinpatent:Paragraph0169;0171

[3]CurrentPatentAssignee:SHENZHENENDURINGBIOTECH;SHENZHENKANGYUANLONGTERMBIOTECHNOLOGYLTD-WO2021/209007,2021,A1Locationinpatent:Page/Pagecolumn55-56;58;60

[4]CurrentPatentAssignee:NANJINGCHEMPIONBIOTECHNOLOGY-WO2022/161452,2022,A1Locationinpatent:Page/Pagecolumn66-67

[5]CurrentPatentAssignee:REGENERONPHARMACEUTICALSINC-US2018/333504,2018,A1Locationinpatent:Paragraph0373

[6]CurrentPatentAssignee:ONTARIOINSTITUTEFORCANCERRESEARCH-WO2019/109188,2019,A1Locationinpatent:Paragraph00308;00310

[7]CurrentPatentAssignee:ONTARIOINSTITUTEFORCANCERRESEARCH-WO2019/119141,2019,A1Locationinpatent:Paragraph00221;00277;00279

[8]CurrentPatentAssignee:ANTIKORBIOPHARMA-WO2016/46574,2016,A1Locationinpatent:Page/Pagecolumn144

[9]Manabe,Shino;Yamaguchi,Yoshiki;Matsumoto,Kana;Fuchigami,Hirobumi;Kawase,Taiji;Hirose,Kenji;Mitani,Ai;Sumiyoshi,Wataru;Kinoshita,Takashi;Abe,Junpei;Yasunaga,Masahiro;Matsumura,Yasuhiro;Ito,Yukishige[BioconjugateChemistry,2019,vol.30,#5,p.1343-1355]

[10]CurrentPatentAssignee:UNIVERSITYOFCAMBRIDGE-WO2020/25108,2020,A1Locationinpatent:Page/Pagecolumn48-49

[11]CurrentPatentAssignee:REMEGEN-US2020/138968,2020,A1Locationinpatent:Paragraph0070-0071;0074-0075

[12]CurrentPatentAssignee:SPIREA-WO2020/128488,2020,A1Locationinpatent:Page/Pagecolumn84-85

[13]CurrentPatentAssignee:SEAGENINC-US2021/300867,2021,A1Locationinpatent:Paragraph0551;0554

[14]CurrentPatentAssignee:DEBIOPHARMRESMANUFACTURING-WO2022/79031,2022,A1Locationinpatent:Page/Pagecolumn201-202

474645-27-7

863971-53-3

Fmoc-VC-PAB-MMAE

[1]OrganicandBiomolecularChemistry,2016,vol.14,p.9501-9518

[2]Patent:WO2019/119141,2019,A1.Locationinpatent:Paragraph00212;00277;00278

[3]Patent:WO2019/109188,2019,A1.Locationinpatent:Paragraph00308;00309

[4]Patent:WO2016/46574,2016,A1.Locationinpatent:Page/Pagecolumn144

[5]Patent:US2018/333504,2018,A1.Locationinpatent:Paragraph0373

1350456-56-2 | Fmoc-Val-Cit-PAB-MMAE