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1221277-90-2,MFCD28396416
Catalog No.:AA00A1D0

1221277-90-2 | GSK 2033

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
99% (HPLC)
in stock  
$198.00   $138.00
- +
10mg
99% (HPLC)
in stock  
$290.00   $203.00
- +
25mg
99% (HPLC)
in stock  
$541.00   $379.00
- +
50mg
99% (HPLC)
in stock  
$877.00   $614.00
- +
100mg
99% (HPLC)
in stock  
$1,471.00   $1,030.00
- +
500mg
99% (HPLC)
in stock  
$4,607.00   $3,225.00
- +
1000mg
99% (HPLC)
in stock  
$7,334.00   $5,134.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00A1D0
Chemical Name:
GSK 2033
CAS Number:
1221277-90-2
Molecular Formula:
C29H28F3NO5S2
Molecular Weight:
591.6615
MDL Number:
MFCD28396416
SMILES:
Cc1cc(C)c(c(c1)C)S(=O)(=O)N(Cc1ccc(o1)C(F)(F)F)Cc1ccc(cc1)c1cccc(c1)S(=O)(=O)C
Properties
Computed Properties
 
Complexity:
1040  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
40  
Hydrogen Bond Acceptor Count:
9  
Rotatable Bond Count:
8  
XLogP3:
6  

Literature

Title: Discovery of tertiary sulfonamides as potent liver X receptor antagonists.

Journal: Journal of medicinal chemistry 20100422

Title: Zuercher WJ, et al. Discovery of tertiary sulfonamides as potent liver X receptor antagonists. J Med Chem. 2010 Apr 22;53(8):3412-6.

Title: Griffett K, et al. Promiscuous activity of the LXR antagonist GSK2033 in a mouse model of fatty liver disease. Biochem Biophys Res Commun. 2016 Oct 21;479(3):424-428.

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SDS
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Tags:1221277-90-2 Molecular Formula|1221277-90-2 MDL|1221277-90-2 SMILES|1221277-90-2 GSK 2033
Catalog No.: AA00A1D0
1221277-90-2,MFCD28396416
1221277-90-2 | GSK 2033
Pack Size： 1mg
Purity： ≥98%
in stock
$46.00 $32.00
Pack Size： 5mg
Purity： 99% (HPLC)
in stock
$198.00 $138.00
Pack Size： 10mg
Purity： 99% (HPLC)
in stock
$290.00 $203.00
Pack Size： 25mg
Purity： 99% (HPLC)
in stock
$541.00 $379.00
Pack Size： 50mg
Purity： 99% (HPLC)
in stock
$877.00 $614.00
Pack Size： 100mg
Purity： 99% (HPLC)
in stock
$1,471.00 $1,030.00
Pack Size： 500mg
Purity： 99% (HPLC)
in stock
$4,607.00 $3,225.00
Pack Size： 1000mg
Purity： 99% (HPLC)
in stock
$7,334.00 $5,134.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA00A1D0
Chemical Name: GSK 2033
CAS Number: 1221277-90-2
Molecular Formula: C29H28F3NO5S2
Molecular Weight: 591.6615
MDL Number: MFCD28396416
SMILES: Cc1cc(C)c(c(c1)C)S(=O)(=O)N(Cc1ccc(o1)C(F)(F)F)Cc1ccc(cc1)c1cccc(c1)S(=O)(=O)C
Properties
Complexity: 1040  
Covalently-Bonded Unit Count: 1  
Heavy Atom Count: 40  
Hydrogen Bond Acceptor Count: 9  
Rotatable Bond Count: 8  
XLogP3: 6  
Literature fold

Title: Discovery of tertiary sulfonamides as potent liver X receptor antagonists.

Journal: Journal of medicinal chemistry20100422

Title: Zuercher WJ, et al. Discovery of tertiary sulfonamides as potent liver X receptor antagonists. J Med Chem. 2010 Apr 22;53(8):3412-6.

Title: Griffett K, et al. Promiscuous activity of the LXR antagonist GSK2033 in a mouse model of fatty liver disease. Biochem Biophys Res Commun. 2016 Oct 21;479(3):424-428.

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