Title: Effect of oestrogen receptors on brain NMDA receptors of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice.
Journal: Journal of neuroendocrinology 20121101
Title: Ifenprodil, a NR2B-selective antagonist of NMDA receptor, inhibits reverse Na+/Ca2+ exchanger in neurons.
Journal: Neuropharmacology 20121101
Title: Involvement of the anterior cingulate cortex in formation, consolidation, and reconsolidation of recent and remote contextual fear memory.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20120914
Title: NMDARs mediate the role of monoamine oxidase A in pathological aggression.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120620
Title: NMDA receptor mediated phosphorylation of GluR1 subunits contributes to the appearance of calcium-permeable AMPA receptors after mechanical stretch injury.
Journal: Neurobiology of disease 20120601
Title: Investigation of the antidyskinetic site of action of metabotropic and ionotropic glutamate receptor antagonists. Intracerebral infusions in 6-hydroxydopamine-lesioned rats with levodopa-induced dyskinesia.
Journal: European journal of pharmacology 20120515
Title: Hippocampus versus entorhinal cortex decoupling by an NR2 subunit-specific block of NMDA receptors in a rat in vitro model of temporal lobe epilepsy.
Journal: Epilepsia 20120501
Title: Reduction of inflammatory pain in female rats after NR2B NMDA cortical antagonism.
Journal: Psicothema 20120501
Title: Effect of NMDA NR2B antagonist on neuropathic pain in two spinal cord injury models.
Journal: Pain 20120501
Title: Role of GluN2A and GluN2B subunits in the formation of filopodia and secondary dendrites in cultured hippocampal neurons.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120201
Title: Isoflurane/nitrous oxide anesthesia induces increases in NMDA receptor subunit NR2B protein expression in the aged rat brain.
Journal: Brain research 20120111
Title: Inhibition of Ca2+/calmodulin-dependent protein kinase II reverses oxaliplatin-induced mechanical allodynia in rats.
Journal: Molecular pain 20120101
Title: Genetic, pharmacological and lesion analyses reveal a selective role for corticohippocampal GLUN2B in a novel repeated swim stress paradigm.
Journal: Neuroscience 20111013
Title: Neuronal NR2B-containing NMDA receptor mediates spinal astrocytic c-Jun N-terminal kinase activation in a rat model of neuropathic pain.
Journal: Brain, behavior, and immunity 20111001
Title: Blockade of NMDA receptors 2A subunit in the dorsal striatum impairs the learning of a complex motor skill.
Journal: Behavioral neuroscience 20111001
Title: Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110831
Title: Blockade of NMDA GluN2B receptors selectively impairs behavioral flexibility but not initial discrimination learning.
Journal: Psychopharmacology 20110801
Title: Involvement of synaptic NR2B-containing NMDA receptors in long-term depression induction in the young rat visual cortex in vitro.
Journal: The Chinese journal of physiology 20110630
Title: Peripheral administration of NR2 antagonists attenuates orofacial formalin-induced nociceptive behavior in rats.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20110601
Title: A silent synapse-based mechanism for cocaine-induced locomotor sensitization.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110601
Title: Dopamine induces a GluN2A-dependent form of long-term depression of NMDA synaptic responses in the nucleus accumbens.
Journal: Neuropharmacology 20110501
Title: Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices.
Journal: Neuropharmacology 20110501
Title: NR2B subunit blockade does not affect motor symptoms induced by 3-nitropropionic acid.
Journal: Neurological research 20110501
Title: Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure.
Journal: Biological psychiatry 20110415
Title: The effects of NMDA receptor antagonists on attentional set-shifting task performance in mice.
Journal: Psychopharmacology 20110401
Title: NR2B subunit-specific NMDA antagonist Ro25-6981 inhibits the expression of conditioned fear: a comparison with the NMDA antagonist MK-801 and fluoxetine.
Journal: Behavioural pharmacology 20110401
Title: Nickel modulates the electrical activity of cultured cortical neurons through a specific effect on N-methyl-D-aspartate receptor channels.
Journal: Neuroscience 20110317
Title: Cyclic adenosine monophosphate-independent tyrosine phosphorylation of NR2B mediates cocaine-induced extracellular signal-regulated kinase activation.
Journal: Biological psychiatry 20110201
Title: [Effects of the neurogenesis stimulator Ro 25-6981 upon formation of spatial skill in adult rats depend on the term of its administration and the animals' ability to learn].
Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20110201
Title: An examination of NMDA receptor contribution to conditioned responding evoked by the conditional stimulus effects of nicotine.
Journal: Psychopharmacology 20110101
Title: Involvement of spinal NR2B-containing NMDA receptors in oxaliplatin-induced mechanical allodynia in rats.
Journal: Molecular pain 20110101
Title: Intracisternal administration of NR2 subunit antagonists attenuates the nociceptive behavior and p-p38 MAPK expression produced by compression of the trigeminal nerve root.
Journal: Molecular pain 20110101
Title: Lack of efficacy of NMDA receptor-NR2B selective antagonists in the R6/2 model of Huntington disease.
Journal: Experimental neurology 20101001
Title: Identification of a novel NR2B-selective NMDA receptor antagonist using a virtual screening approach.
Journal: Bioorganic & medicinal chemistry letters 20100915
Title: mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists.
Journal: Science (New York, N.Y.) 20100820
Title: Long-lasting adaptations of the NR2B-containing NMDA receptors in the dorsomedial striatum play a crucial role in alcohol consumption and relapse.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100728
Title: Inverse relationship between seizure expression and extrasynaptic NMDAR function following chronic NMDAR inhibition.
Journal: Epilepsia 20100701
Title: Stoichiometry of N-methyl-D-aspartate receptors within the suprachiasmatic nucleus.
Journal: Journal of neurophysiology 20100601
Title: Contribution of the spinal cord BDNF to the development of neuropathic pain by activation of the NR2B-containing NMDA receptors in rats with spinal nerve ligation.
Journal: Experimental neurology 20100401
Title: Effects of agents targeting glutamatergic systems on marble-burying behavior.
Journal: Neuroscience letters 20100303
Title: NMDA NR2B subtype-selective receptor antagonists fail to antagonize electrically-precipitated seizures and elicit popping in mice.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20100301
Title: Effects of acute stress and GluN2B-containing NMDA receptor antagonism on object and object-place recognition memory.
Journal: Neurobiology of learning and memory 20100201
Title: Intracisternal administration of NR2 antagonists attenuates facial formalin-induced nociceptive behavior in rats.
Journal: Journal of orofacial pain 20100101
Title: Postsynaptic response to stimulation of the Schaffer collaterals with properties similar to those of synaptosomal aspartate release.
Journal: Brain research 20091027
Title: NR2A-containing NMDA receptors are required for L-LTP induction and depotentiation in CA1 region of hippocampal slices.
Journal: The European journal of neuroscience 20090601
Title: A novel protein complex in membrane rafts linking the NR2B glutamate receptor and autophagy is disrupted following traumatic brain injury.
Journal: Journal of neurotrauma 20090501
Title: Platelet-derived growth factor selectively inhibits NR2B-containing N-methyl-D-aspartate receptors in CA1 hippocampal neurons.
Journal: The Journal of biological chemistry 20090320
Title: Late phase of long-term potentiation induced by co-application of N-methyl-d-aspartic acid and the antagonist of NR2B-containing N-methyl-d-aspartic acid receptors in rat hippocampus.
Journal: Neuroscience 20090303
Title: Development of 3-substituted-1H-indole derivatives as NR2B/NMDA receptor antagonists.
Journal: Bioorganic & medicinal chemistry 20090215
Title: Role of the spinal cord NR2B-containing NMDA receptors in the development of neuropathic pain.
Journal: Experimental neurology 20090201
Title: Fear memory impairing effects of systemic treatment with the NMDA NR2B subunit antagonist, Ro 25-6981, in mice: attenuation with ageing.
Journal: Pharmacology, biochemistry, and behavior 20090101
Title: A role of periaqueductal grey NR2B-containing NMDA receptor in mediating persistent inflammatory pain.
Journal: Molecular pain 20090101
Title: D1/5 receptor-mediated enhancement of LTP requires PKA, Src family kinases, and NR2B-containing NMDARs.
Journal: Neuropharmacology 20081001
Title: Differential effect of NR2A and NR2B subunit selective NMDA receptor antagonists on striato-pallidal neurons: relationship to motor response in the 6-hydroxydopamine model of parkinsonism.
Journal: Journal of neurochemistry 20080701
Title: Cerebellar granule cells cultured from adolescent rats express functional NMDA receptors: an in vitro model for studying the developing cerebellum.
Journal: Journal of neurochemistry 20080701
Title: D-serine augments NMDA-NR2B receptor-dependent hippocampal long-term depression and spatial reversal learning.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080401
Title: Spinal cord long-term potentiation is attenuated by the NMDA-2B receptor antagonist Ro 25-6981.
Journal: Acta physiologica (Oxford, England) 20080301
Title: Tonic facilitation of glutamate release by glycine binding sites on presynaptic NR2B-containing NMDA autoreceptors in the rat visual cortex.
Journal: Neuroscience letters 20080227
Title: Intrathecal high-dose histamine induces spinally-mediated nociceptive behavioral responses through a polyamine site of NMDA receptors.
Journal: European journal of pharmacology 20080226
Title: Brain-derived neurotrophic factor activation of extracellular signal-regulated kinase is autonomous from the dominant extrasynaptic NMDA receptor extracellular signal-regulated kinase shutoff pathway.
Journal: Neuroscience 20080124
Title: Effects of pan- and subtype-selective N-methyl-D-aspartate receptor antagonists on cortical spreading depression in the rat: therapeutic potential for migraine.
Journal: The Journal of pharmacology and experimental therapeutics 20070501
Title: Selective NR1/2B N-methyl-D-aspartate receptor antagonists among indole-2-carboxamides and benzimidazole-2-carboxamides.
Journal: Journal of medicinal chemistry 20070308
Title: Contribution of NMDA receptor NR2B subunit to synaptic plasticity during associative learning in behaving rats.
Journal: The European journal of neuroscience 20070201
Title: Activation of NR2B-containing NMDA receptors is not required for NMDA receptor-dependent long-term depression.
Journal: Neuropharmacology 20070101
Title: Differential roles of NR2A and NR2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus.
Journal: Neuropharmacology 20070101
Title: NR2B antagonists restrict spatiotemporal spread of activity in a rat model of cortical dysplasia.
Journal: Epilepsy research 20061201
Title: N-methyl-D-aspartate receptor-dependent long-term potentiation in CA1 region affects synaptic expression of glutamate receptor subunits and associated proteins in the whole hippocampus.
Journal: Neuroscience 20060901
Title: Benzimidazole-2-carboxamides as novel NR2B selective NMDA receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20060901
Title: NR2B-containing N-methyl-D-aspartate subtype glutamate receptors regulate the acute stress effect on hippocampal long-term potentiation/long-term depression in vivo.
Journal: Neuroreport 20060821
Title: Estradiol-induced increase in the magnitude of long-term potentiation is prevented by blocking NR2B-containing receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060816
Title: An animal model of chronic inflammatory pain: pharmacological and temporal differentiation from acute models.
Journal: European journal of pain (London, England) 20060801
Title: Effects of N-methyl-D-aspartate receptor antagonism on neuroleptic-induced orofacial dyskinesias.
Journal: Psychopharmacology 20060401
Title: Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060315
Title: Glutamate-based therapeutic approaches: NR2B receptor antagonists.
Journal: Current opinion in pharmacology 20060201
Title: Novel blockade of protein kinase A-mediated phosphorylation of AMPA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060125
Title: Tonic facilitation of glutamate release by presynaptic NR2B-containing NMDA receptors is increased in the entorhinal cortex of chronically epileptic rats.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060111
Title: Role of neuronal NR2B subunit-containing NMDA receptor-mediated Ca2+ influx and astrocytic activation in cultured mouse cortical neurons and astrocytes.
Journal: Synapse (New York, N.Y.) 20060101
Title: Contribution of NR2A and NR2B NMDA subunits to bidirectional synaptic plasticity in the hippocampus in vivo.
Journal: Hippocampus 20060101
Title: Stress evoked by opiate withdrawal facilitates hippocampal LTP in vivo.
Journal: Hippocampus 20060101
Title: Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memory.
Journal: Neuron 20050915
Title: Functional roles of NMDA receptor NR2A and NR2B subunits in the acute intoxicating effects of ethanol in mice.
Journal: Synapse (New York, N.Y.) 20050615
Title: Selective subunit antagonists suggest an inhibitory relationship between NR2B and NR2A-subunit containing N-methyl-D: -aspartate receptors in hippocampal slices.
Journal: Experimental brain research 20050401
Title: BDNF enhancement of postsynaptic NMDA receptors is blocked by ethanol.
Journal: Synapse (New York, N.Y.) 20050101
Title: The NR2B-selective N-methyl-D-aspartate receptor antagonist Ro 25-6981 [(+/-)-(R*,S*)-alpha-(4-hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidine propanol] potentiates the effect of nicotine on locomotor activity and dopamine release in the nucleus accumbens.
Journal: The Journal of pharmacology and experimental therapeutics 20041101
Title: Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908
Title: Oxamides as novel NR2B selective NMDA receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20040802
Title: Modulation of morphine analgesia by site-specific N-methyl-D-aspartate receptor antagonists: dependence on sex, site of antagonism, morphine dose, and time.
Journal: Pain 20040601
Title: Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity.
Journal: Science (New York, N.Y.) 20040514
Title: Antiparkinsonian activity of Ro 25-6981, a NR2B subunit specific NMDA receptor antagonist, in animal models of Parkinson's disease.
Journal: Experimental neurology 20040501
Title: The NMDA receptor NR2B subunit: a valid therapeutic target for multiple CNS pathologies.
Journal: Current medicinal chemistry 20040201
Title: Identification of critical residues in the amino terminal domain of the human NR2B subunit involved in the RO 25-6981 binding pocket.
Journal: The Journal of pharmacology and experimental therapeutics 20031201
Title: Indole-2-carboxamides as novel NR2B selective NMDA receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20031103
Title: Asymmetrical allocation of NMDA receptor epsilon2 subunits in hippocampal circuitry.
Journal: Science (New York, N.Y.) 20030509
Title: Role of the NMDA receptor NR2B subunit in the discriminative stimulus effects of ketamine.
Journal: Behavioural pharmacology 20030501
Title: 2-(3,4-Dihydro-1H-isoquinolin-2yl)-pyridines as a novel class of NR1/2B subtype selective NMDA receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20030310
Title: Novel N1-(benzyl)cinnamamidine derived NR2B subtype-selective NMDA receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20030224
Title: The NMDA receptor NR2B subtype selective antagonist Ro 25-6981 aggravates paroxysmal dyskinesia in the dt(sz) mutant.
Journal: European journal of pharmacology 20030101
Title: Blockade of NMDA receptor subtype NR2B prevents seizures but not apoptosis of dentate gyrus neurons in bacterial meningitis in infant rats.
Journal: BMC neuroscience 20030101
Title: Role of NR2B-containing N-methyl-D-aspartate receptors in haloperidol-induced c-Fos expression in the striatum and nucleus accumbens.
Journal: Neuroscience 20030101
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: Discovery of (R)-1-[2-hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4-methyl-benzyl)-piperidin-4-ol: a novel NR1/2B subtype selective NMDA receptor antagonist.
Journal: Bioorganic & medicinal chemistry letters 20010820
Title: Estrogen-like activity of tamoxifen and raloxifene on NMDA receptor binding and expression of its subunits in rat brain.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010801
Title: NMDA receptor antagonists do not block the development of sensitization of catalepsy, but make its expression state-dependent.
Journal: Behavioural pharmacology 20010401
Title: Pharmacological characterization of interactions of RO 25-6981 with the NR2B (epsilon2) subunit.
Journal: European journal of pharmacology 20010330
Title: Löschmann PA, et al. Antiparkinsonian activity of Ro 25-6981, a NR2B subunit specific NMDA receptor antagonist, in animal models of Parkinson's disease. Exp Neurol. 2004 May;187(1):86-93.
Title: Szczurowska E,et al. Different action of a specific NR2B/NMDA antagonist Ro 25-6981 on cortical evoked potentials and epileptic afterdischarges in immature rats. Brain Res Bull. 2015 Feb;111:1-8.
Title: Jiang M, et al. Antinociception and prevention of hyperalgesia by intrathecal administration of Ro 25-6981, a highly selective antagonist of the 2B subunit of N-methyl-D-aspartate receptor. Pharmacol Biochem Behav. 2013 Nov;112:56-63.
