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1312991-76-6,MFCD06798375
Catalog No.:AA003ART

1312991-76-6 | Ro 25-6981 Maleate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$82.00   $57.00
- +
5mg
98%
in stock  
$218.00   $153.00
- +
10mg
≥95%
in stock  
$238.00   $166.00
- +
50mg
98%
in stock  
$906.00   $634.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003ART
Chemical Name:
Ro 25-6981 Maleate
CAS Number:
1312991-76-6
Molecular Formula:
C26H33NO6
Molecular Weight:
455.5433
MDL Number:
MFCD06798375
SMILES:
C[C@H]([C@H](c1ccc(cc1)O)O)CN1CCC(CC1)Cc1ccccc1.OC(=O)/C=C\C(=O)O
Properties
Computed Properties
 
Complexity:
485  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
8  

Literature

Title: Löschmann PA, et al. Antiparkinsonian activity of Ro 25-6981, a NR2B subunit specific NMDA receptor antagonist, in animal models of Parkinson's disease. Exp Neurol. 2004 May;187(1):86-93.

Title: Szczurowska E,et al. Different action of a specific NR2B/NMDA antagonist Ro 25-6981 on cortical evoked potentials and epileptic afterdischarges in immature rats. Brain Res Bull. 2015 Feb;111:1-8.

Title: Jiang M, et al. Antinociception and prevention of hyperalgesia by intrathecal administration of Ro 25-6981, a highly selective antagonist of the 2B subunit of N-methyl-D-aspartate receptor. Pharmacol Biochem Behav. 2013 Nov;112:56-63.

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SDS
Tags:1312991-76-6 Molecular Formula|1312991-76-6 MDL|1312991-76-6 SMILES|1312991-76-6 Ro 25-6981 Maleate