Title: Chronic alcohol consumption enhances iNKT cell maturation and activation.
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Title: Enhanced TCR footprint by a novel glycolipid increases NKT-dependent tumor protection.
Journal: Journal of immunology (Baltimore, Md. : 1950)20130915
Title: Bacterial CD1d-restricted glycolipids induce IL-10 production by human regulatory T cells upon cross-talk with invariant NKT cells.
Journal: Journal of immunology (Baltimore, Md. : 1950)20130901
Title: Slam haplotype 2 promotes NKT but suppresses Vγ4+ T-cell activation in coxsackievirus B3 infection leading to increased liver damage but reduced myocarditis.
Journal: The American journal of pathology20130201
Title: Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs.
Journal: Proceedings of the National Academy of Sciences of the United States of America20130129
Title: Lack of PD-L1 expression by iNKT cells improves the course of influenza A infection.
Journal: PloS one20130101
Title: CD1d-dependent, iNKT-cell cytotoxicity against keratinocytes in allergic contact dermatitis.
Journal: Experimental dermatology20121201
Title: Human and mouse type I natural killer T cell antigen receptors exhibit different fine specificities for CD1d-antigen complex.
Journal: The Journal of biological chemistry20121109
Title: The molecular basis for recognition of CD1d/α-galactosylceramide by a human non-Vα24 T cell receptor.
Journal: PLoS biology20121001
Title: Key role for respiratory CD103(+) dendritic cells, IFN-γ, and IL-17 in protection against Streptococcus pneumoniae infection in response to α-galactosylceramide.
Journal: The Journal of infectious diseases20120901
Title: Type II natural killer T cells use features of both innate-like and conventional T cells to recognize sulfatide self antigens.
Journal: Nature immunology20120901
Title: C-Glycosphingolipids with an exo-methylene substituent: stereocontrolled synthesis and immunostimulation of mouse and human natural killer T lymphocytes.
Journal: Chembiochem : a European journal of chemical biology20120813
Title: RCAI-84, 91, and 105-108, ureido and thioureido analogs of KRN7000: their synthesis and bioactivity for mouse lymphocytes to produce Th1-biased cytokines.
Journal: Bioorganic & medicinal chemistry20120715
Title: Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice.
Journal: Proceedings of the National Academy of Sciences of the United States of America20120508
Title: Bacterial species-characteristic profiles of molecular species, and the antigenicity of phospholipids and glycolipids in symbiotic Lactobacillus, Staphylococcus and Streptococcus species.
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Title: Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor.
Journal: The EMBO journal20120418
Title: Structural and functional characterization of a novel nonglycosidic type I NKT agonist with immunomodulatory properties.
Journal: Journal of immunology (Baltimore, Md. : 1950)20120301
Title: 3-fluoro- and 3,3-difluoro-3,4-dideoxy-KRN7000 analogues as new potent immunostimulator agents: total synthesis and biological evaluation in human invariant natural killer T cells and mice.
Journal: Journal of medicinal chemistry20120209
Title: Structural basis for the recognition of C20:2-αGalCer by the invariant natural killer T cell receptor-like antibody L363.
Journal: The Journal of biological chemistry20120106
Title: Natural variations at position 93 of the invariant Vα24-Jα18 α chain of human iNKT-cell TCRs strongly impact on CD1d binding.
Journal: European journal of immunology20120101
Title: Crystal structures of bovine CD1d reveal altered αGalCer presentation and a restricted A' pocket unable to bind long-chain glycolipids.
Journal: PloS one20120101
Title: Activation of Invariant NKT cells with glycolipid ligand α-galactosylceramide ameliorates glucose-6-phosphate isomerase peptide-induced arthritis.
Journal: PloS one20120101
Title: Divergent synthetic approach to 6''-modified α-GalCer analogues.
Journal: Organic & biomolecular chemistry20111221
Title: Total synthesis of α-1C-galactosylceramide, an immunostimulatory C-glycosphingolipid, and confirmation of the stereochemistry in the first-generation synthesis.
Journal: The Journal of organic chemistry20111104
Title: Invariant NKT cell defects in vitamin D receptor knockout mice prevents experimental lung inflammation.
Journal: Journal of immunology (Baltimore, Md. : 1950)20111101
Title: Prevention of type 1 diabetes by inducing subclinical dermatitis on a small area.
Journal: Diabetes/metabolism research and reviews20111101
Title: Unique interplay between sugar and lipid in determining the antigenic potency of bacterial antigens for NKT cells.
Journal: PLoS biology20111101
Title: Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria.
Journal: Nature immunology20111001
Title: Cutting edge: structural basis for the recognition of β-linked glycolipid antigens by invariant NKT cells.
Journal: Journal of immunology (Baltimore, Md. : 1950)20110901
Title: Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors.
Journal: Nature immunology20110731
Title: A semi-invariant Vα10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties.
Journal: Nature immunology20110612
Title: Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection.
Journal: The Journal of experimental medicine20110606
Title: Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.
Journal: The EMBO journal20110601
Title: Functional invariant NKT cells in pig lungs regulate the airway hyperreactivity: a potential animal model.
Journal: Journal of clinical immunology20110401
Title: A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells.
Journal: Immunity20110325
Title: A molecular basis for NKT cell recognition of CD1d-self-antigen.
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Title: Synthesis of a versatile building block for the preparation of 6-N-derivatized α-galactosyl ceramides: rapid access to biologically active glycolipids.
Journal: The Journal of organic chemistry20110107
Title: Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation.
Journal: Bioorganic & medicinal chemistry20110101
Title: Development of spontaneous anergy in invariant natural killer T cells in a mouse model of dyslipidemia.
Journal: Arteriosclerosis, thrombosis, and vascular biology20100901
Title: Synthesis and biological activity of ester and ether analogues of alpha-galactosylceramide (KRN7000).
Journal: Carbohydrate research20100816
Title: Invariant NKT cells are required for antitumor responses induced by host-versus-graft responses.
Journal: Journal of immunology (Baltimore, Md. : 1950)20100815
Title: Dietary fatty acids modulate antigen presentation to hepatic NKT cells in nonalcoholic fatty liver disease.
Journal: Journal of lipid research20100701
Title: Plasticity of invariant NKT cell regulation of allergic airway disease is dependent on IFN-gamma production.
Journal: Journal of immunology (Baltimore, Md. : 1950)20100701
Title: Slam haplotypes modulate the response to lipopolysaccharide in vivo through control of NKT cell number and function.
Journal: Journal of immunology (Baltimore, Md. : 1950)20100701
Title: Synthesis and biological activity of alpha-L-fucosyl ceramides, analogues of the potent agonist, alpha-D-galactosyl ceramide KRN7000.
Journal: Bioorganic & medicinal chemistry letters20100601
Title: Fatty acid amide hydrolase shapes NKT cell responses by influencing the serum transport of lipid antigen in mice.
Journal: The Journal of clinical investigation20100601
Title: Innate-like control of human iNKT cell autoreactivity via the hypervariable CDR3beta loop.
Journal: PLoS biology20100601
Title: CD1d-dependent B-cell help by NK-like T cells leads to enhanced and sustained production of Bacillus anthracis lethal toxin-neutralizing antibodies.
Journal: Infection and immunity20100401
Title: A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity.
Journal: Journal of immunology (Baltimore, Md. : 1950)20100215
Title: Syntheses and biological activities of KRN7000 analogues having aromatic residues in the acyl and backbone chains with varying stereochemistry.
Journal: Bioorganic & medicinal chemistry letters20100201
Title: Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells.
Journal: Proceedings of the National Academy of Sciences of the United States of America20100126
Title: PD-L1 and PD-L2 modulate airway inflammation and iNKT-cell-dependent airway hyperreactivity in opposing directions.
Journal: Mucosal immunology20100101
Title: Mechanisms for glycolipid antigen-driven cytokine polarization by Valpha14i NKT cells.
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Title: Bacillus anthracis lethal toxin disrupts TCR signaling in CD1d-restricted NKT cells leading to functional anergy.
Journal: PLoS pathogens20090901
Title: Focus on the controversial activation of human iNKT cells by 4-deoxy analogue of KRN7000.
Journal: Journal of medicinal chemistry20090813
Title: Synthesis and biological activity of alpha-galactosyl ceramide KRN7000 and galactosyl (alpha1-->2) galactosyl ceramide.
Journal: Bioorganic & medicinal chemistry letters20090801
Title: Skin and peripheral lymph node invariant NKT cells are mainly retinoic acid receptor-related orphan receptor (gamma)t+ and respond preferentially under inflammatory conditions.
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Title: Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors.
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Title: Cutting edge: B and T lymphocyte attenuator signaling on NKT cells inhibits cytokine release and tissue injury in early immune responses.
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Title: Induction of airway hyperreactivity by IL-25 is dependent on a subset of invariant NKT cells expressing IL-17RB.
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Title: Synthesis of alpha-galactosyl ceramide (KRN7000) and analogues thereof via a common precursor and their preliminary biological assessment.
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Title: Synthesis and in vivo evaluation of 4-deoxy-4,4-difluoro-KRN7000.
Journal: Organic letters20081016
Title: The first synthesis of a thioglycoside analogue of the immunostimulant KRN7000.
Journal: Organic letters20081016
Title: RCAI-17, 22, 24-26, 29, 31, 34-36, 38-40, and 88, the analogs of KRN7000 with a sulfonamide linkage: their synthesis and bioactivity for mouse natural killer T cells to produce Th2-biased cytokines.
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Title: Prolongation of cardiac allograft survival by rapamycin and the invariant natural killer T cell glycolipid agonist OCH.
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Title: Alpha-lactosylceramide as a novel 'sugar-capped' CD1d ligand for natural killer T cells: biased cytokine profile and therapeutic activities.
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Title: Glycolipid-activated NKT cells support the induction of persistent plasma cell responses and antibody titers.
Journal: European journal of immunology20080401
Title: RCAI-8, 9, 18, 19, and 49-52, conformationally restricted analogues of KRN7000 with an azetidine or a pyrrolidine ring: Their synthesis and bioactivity for mouse natural killer T cells to produce cytokines.
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Title: Immunization with dendritic cells loaded with alpha-galactosylceramide at priming phase, but not at boosting phase, enhances cytotoxic T lymphocyte activity against infection by intracellular bacteria.
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Title: iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity.
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