188181-42-2,MFCD19443751
Catalog No.:AA00ANPM

188181-42-2 | 5'-O-(Elaidoyl) 1-β-D-arabinofuranosylcytosine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$15.00   $11.00
- +
5mg
98%
in stock  
$37.00   $26.00
- +
10mg
98%
in stock  
$54.00   $38.00
- +
50mg
98%
in stock  
$153.00   $107.00
- +
100mg
98%
in stock  
$258.00   $181.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00ANPM
Chemical Name:
5'-O-(Elaidoyl) 1-β-D-arabinofuranosylcytosine
CAS Number:
188181-42-2
Molecular Formula:
C27H45N3O6
Molecular Weight:
507.6627
MDL Number:
MFCD19443751
SMILES:
CCCCCCCC/C=C/CCCCCCCC(=O)OC[C@H]1O[C@H]([C@H]([C@@H]1O)O)n1ccc(nc1=O)N
Properties
Computed Properties
 
Complexity:
754  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
1  
Formal Charge:
0  
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
19  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
5.7  

Downstream Synthesis Route
112-77-6    69-74-9   
elacytarabine 

[1]Patent:US6335322,2002,B1.Locationinpatent:Example1

Literature

Title: Metabolism and accumulation of the lipophilic deoxynucleoside analogs elacytarabine and CP-4126.

Journal: Investigational new drugs 20121001

Title: Elacytarabine has single-agent activity in patients with advanced acute myeloid leukaemia.

Journal: British journal of haematology 20120901

Title: Phase I and pharmacokinetic study of elacytarabine, a novel 5'-elaidic acid derivative of cytarabine, in adults with refractory hematological malignancies.

Journal: Leukemia 20120701

Title: Elacytarabine, a novel 5'-elaidic acid derivative of cytarabine, and idarubicin combination is active in refractory acute myeloid leukemia.

Journal: Leukemia research 20120401

Title: Elacytarabine--lipid vector technology overcoming drug resistance in acute myeloid leukemia.

Journal: Expert opinion on investigational drugs 20111201

Title: A phase I-II study of elacytarabine (CP-4055) in the treatment of patients with ovarian cancer resistant or refractory to platinum therapy.

Journal: Cancer chemotherapy and pharmacology 20111101

Title: Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity.

Journal: Current medicinal chemistry 20110101

Title: The activity of the lipophilic nucleoside derivatives elacytarabine and CP-4126 in a panel of tumor cell lines resistant to nucleoside analogues.

Journal: Nucleosides, nucleotides & nucleic acids 20100601

Title: Induction of resistance to the lipophilic cytarabine prodrug elacytarabine (CP-4055) in CEM leukemic cells.

Journal: Nucleosides, nucleotides & nucleic acids 20100601

Title: Cell cycle effects of fatty acid derivatives of cytarabine, CP-4055, and of gemcitabine, CP-4126, as basis for the interaction with oxaliplatin and docetaxel.

Journal: International journal of oncology 20100101

Title: Intravenous administration of CP-4055 (ELACYT) in patients with solid tumours. A Phase I study.

Journal: Acta oncologica (Stockholm, Sweden) 20090101

Title: CP-4055 and CP-4126 are active in ara-C and gemcitabine-resistant lymphoma cell lines.

Journal: British journal of haematology 20090101

Title: Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells.

Journal: Leukemia & lymphoma 20080401

Title: Antiproliferative activity and mechanism of action of fatty acid derivatives of arabinofuranosylcytosine in leukemia and solid tumor cell lines.

Journal: Biochemical pharmacology 20040201

Title: DiNardo CD, et al. Elacytarabine (CP-4055) in the treatment of acute myeloid leukemia. Future Oncol. 2013 Aug;9(8):1073-82.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 188181-42-2
Tags:188181-42-2 Molecular Formula|188181-42-2 MDL|188181-42-2 SMILES|188181-42-2 5'-O-(Elaidoyl) 1-β-D-arabinofuranosylcytosine
Catalog No.: AA00ANPM
188181-42-2,MFCD19443751
188181-42-2 | 5'-O-(Elaidoyl) 1-β-D-arabinofuranosylcytosine
Pack Size: 1mg
Purity: 98%
in stock
$15.00 $11.00
Pack Size: 5mg
Purity: 98%
in stock
$37.00 $26.00
Pack Size: 10mg
Purity: 98%
in stock
$54.00 $38.00
Pack Size: 50mg
Purity: 98%
in stock
$153.00 $107.00
Pack Size: 100mg
Purity: 98%
in stock
$258.00 $181.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00ANPM
Chemical Name: 5'-O-(Elaidoyl) 1-β-D-arabinofuranosylcytosine
CAS Number: 188181-42-2
Molecular Formula: C27H45N3O6
Molecular Weight: 507.6627
MDL Number: MFCD19443751
SMILES: CCCCCCCC/C=C/CCCCCCCC(=O)OC[C@H]1O[C@H]([C@H]([C@@H]1O)O)n1ccc(nc1=O)N
Properties
Complexity: 754  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 4  
Defined Bond Stereocenter Count: 1  
Formal Charge: 0  
Heavy Atom Count: 36  
Hydrogen Bond Acceptor Count: 6  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 19  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 5.7  
Downstream Synthesis Route
112-77-6    69-74-9   
elacytarabine 

[1]Patent:US6335322,2002,B1.Locationinpatent:Example1

Literature fold

Title: Metabolism and accumulation of the lipophilic deoxynucleoside analogs elacytarabine and CP-4126.

Journal: Investigational new drugs20121001

Title: Elacytarabine has single-agent activity in patients with advanced acute myeloid leukaemia.

Journal: British journal of haematology20120901

Title: Phase I and pharmacokinetic study of elacytarabine, a novel 5'-elaidic acid derivative of cytarabine, in adults with refractory hematological malignancies.

Journal: Leukemia20120701

Title: Elacytarabine, a novel 5'-elaidic acid derivative of cytarabine, and idarubicin combination is active in refractory acute myeloid leukemia.

Journal: Leukemia research20120401

Title: Elacytarabine--lipid vector technology overcoming drug resistance in acute myeloid leukemia.

Journal: Expert opinion on investigational drugs20111201

Title: A phase I-II study of elacytarabine (CP-4055) in the treatment of patients with ovarian cancer resistant or refractory to platinum therapy.

Journal: Cancer chemotherapy and pharmacology20111101

Title: Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity.

Journal: Current medicinal chemistry20110101

Title: The activity of the lipophilic nucleoside derivatives elacytarabine and CP-4126 in a panel of tumor cell lines resistant to nucleoside analogues.

Journal: Nucleosides, nucleotides & nucleic acids20100601

Title: Induction of resistance to the lipophilic cytarabine prodrug elacytarabine (CP-4055) in CEM leukemic cells.

Journal: Nucleosides, nucleotides & nucleic acids20100601

Title: Cell cycle effects of fatty acid derivatives of cytarabine, CP-4055, and of gemcitabine, CP-4126, as basis for the interaction with oxaliplatin and docetaxel.

Journal: International journal of oncology20100101

Title: Intravenous administration of CP-4055 (ELACYT) in patients with solid tumours. A Phase I study.

Journal: Acta oncologica (Stockholm, Sweden)20090101

Title: CP-4055 and CP-4126 are active in ara-C and gemcitabine-resistant lymphoma cell lines.

Journal: British journal of haematology20090101

Title: Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells.

Journal: Leukemia & lymphoma20080401

Title: Antiproliferative activity and mechanism of action of fatty acid derivatives of arabinofuranosylcytosine in leukemia and solid tumor cell lines.

Journal: Biochemical pharmacology20040201

Title: DiNardo CD, et al. Elacytarabine (CP-4055) in the treatment of acute myeloid leukemia. Future Oncol. 2013 Aug;9(8):1073-82.

Building Blocks More >
189107-45-7
189107-45-7
1-Methyl-1h-indazole-5-carbonitrile
AA00AO5W | MFCD12028575
18486-69-6
18486-69-6
(-)-Myrtenal
AA00AOHH | MFCD00074768
19017-00-6
19017-00-6
1H-Indole,1-(2-propynyl)-
AA00AOQQ | MFCD09263947
167498-29-5
167498-29-5
Z-FY-CHO
AA00AP0V | MFCD00942274
1846-70-4
1846-70-4
2-NONYNOIC ACID
AA00AP7U | MFCD00014373
169750-76-9
169750-76-9
tert-Butyl methyl(piperidin-3-ylmethyl)carbamate
AA00APEF | MFCD06800386
171047-01-1
171047-01-1
3'-Hydroxybiphenyl-3-carboxylic acid
AA00APLH | MFCD04117370
1631-29-4
1631-29-4
1-(4-Chlorophenyl)-1H-pyrrole-2,5-dione
AA00APUF | MFCD00022574
152932-65-5
152932-65-5
3'-(O-SO3NA)GAL-BETA1,4(FUC-ALPHA1,3)GLCNAC, NA
AA00AQ5H | MFCD06656107
146877-98-7
146877-98-7
2'-DEOXYGUANOSINE 5'-MONOPHOSPHATE, DISO DIUM SALT HYDRATE
AA00AQAI | MFCD00150758
Submit
© 2017 AA BLOCKS, INC. All rights reserved.