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69-74-9,MFCD00012839
Catalog No.:AA00IBT9

69-74-9 | Cytarabine HCl

Pack Size
Purity
Availability
Price(USD)
Quantity
  
25mg
97%
in stock  
$6.00   $4.00
- +
100mg
97%
in stock  
$7.00   $5.00
- +
1g
97%
in stock  
$11.00   $8.00
- +
5g
97%
in stock  
$13.00   $9.00
- +
10g
97%
in stock  
$18.00   $13.00
- +
25g
97%
in stock  
$44.00   $31.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IBT9
Chemical Name:
Cytarabine HCl
CAS Number:
69-74-9
Molecular Formula:
C9H14ClN3O5
Molecular Weight:
279.6776
MDL Number:
MFCD00012839
SMILES:
OC[C@@H]1O[C@@H]([C@@H]([C@H]1O)O)n1ccc(nc1=O)N.Cl
Properties
Computed Properties
 
Complexity:
383  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
2  

Literature

Title: Tobias, S.C. and R.F. Borch, Synthesis and biological evaluation of a cytarabine phosphoramidate prodrug. Mol Pharm, 2004. 1(2): p. 112-6.

Title: Shepshelovich D, et al. Pharmacodynamics of cytarabine induced leucopenia: a retrospective cohort study. Br J Clin Pharmacol. 2015 Apr;79(4):685-91.

Title: Besirli, C.G., et al. Cytosine arabinoside rapidly activates Bax-dependent apoptosis and a delayed Bax-independent death pathway in sympathetic neurons. Cell Death Differ, 2003. 10(9): p. 1045-58.

Title: Yamauchi, H., et al., Involvement of p53 in 1-beta-D-arabinofuranosylcytosine-induced trophoblastic cell apoptosis and impaired proliferation in rat placenta. Biol Reprod, 2004. 70(6): p. 1762-7.

Title: Richel, D.J., et al., Comparison of the antileukaemic activity of 5 aza-2-deoxycytidine and arabinofuranosyl-cytosine in rats with myelocytic leukaemia. Br J Cancer, 1988. 58(6): p. 730-3.

Title: Renis HE. Antiviral activity of cytarabine in herpesvirus-infected rats. Antimicrob Agents Chemother. 1973 Oct;4(4):439-44.

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SDS
Tags:69-74-9 Molecular Formula|69-74-9 MDL|69-74-9 SMILES|69-74-9 Cytarabine HCl