Title: Polychlorinated biphenyl 104 promotes migration of endometrial stromal cells in endometriosis.
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Title: Irreversible protein kinase inhibitors: balancing the benefits and risks.
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Journal: Neuro-oncology 20120301
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Journal: Antioxidants & redox signaling 20120215
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Journal: Experimental neurology 20120201
Title: Phenylbutyrate suppresses distinct skin reactions that are enhanced by blockade of epidermal growth factor receptor signaling.
Journal: Journal of dermatological science 20111201
Title: Epidermal growth factor receptor inhibition augments the expression of MHC class I and II genes.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110701
Title: Irritant activation of epithelial cells is mediated via protease-dependent EGFR activation.
Journal: The Journal of investigative dermatology 20110201
Title: Parasympathetic innervation maintains epithelial progenitor cells during salivary organogenesis.
Journal: Science (New York, N.Y.) 20100924
Title: Ultraviolet B radiation of human skin generates platelet-activating factor receptor agonists.
Journal: Photochemistry and photobiology 20100701
Title: Synthesis and biological evaluation of 4-anilinoquinolines as potent inhibitors of epidermal growth factor receptor.
Journal: Journal of medicinal chemistry 20100408
Title: Novel irreversible epidermal growth factor receptor inhibitors by chemical modulation of the cysteine-trap portion.
Journal: Journal of medicinal chemistry 20100311
Title: Chemogenomic profiling provides insights into the limited activity of irreversible EGFR Inhibitors in tumor cells expressing the T790M EGFR resistance mutation.
Journal: Cancer research 20100201
Title: Off-target effects of epidermal growth factor receptor antagonists mediate retinal ganglion cell disinhibited axon growth.
Journal: Brain : a journal of neurology 20091101
Title: Epidermal growth factor receptor inhibitors promote CNS axon growth through off-target effects on glia.
Journal: Neurobiology of disease 20091001
Title: Tissue inhibitor of metalloproteinase-3 inhibits neonatal mouse cardiomyocyte proliferation via EGFR/JNK/SP-1 signaling.
Journal: American journal of physiology. Cell physiology 20090401
Title: Genistein-mediated inhibition of glycosaminoglycan synthesis, which corrects storage in cells of patients suffering from mucopolysaccharidoses, acts by influencing an epidermal growth factor-dependent pathway.
Journal: Journal of biomedical science 20090101
Title: A liquid chromatography mass spectrometry assay for determination of PD168393, a specific and irreversible inhibitor of erbB membrane tyrosine kinases, in rat serum.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081215
Title: Clinical stage EGFR inhibitors irreversibly alkylate Bmx kinase.
Journal: Bioorganic & medicinal chemistry letters 20081115
Title: MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20080601
Title: Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR.
Journal: Bioorganic & medicinal chemistry 20080401
Title: Expression of signaling mediators downstream of EGF-receptor predict sensitivity to small molecule inhibitors directed against the EGF-receptor pathway.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080201
Title: Protease activated receptor 2 and epidermal growth factor receptor are involved in the regulation of human sperm motility.
Journal: Asian journal of andrology 20070901
Title: Inhibiting epidermal growth factor receptor improves structural, locomotor, sensory, and bladder recovery from experimental spinal cord injury.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070613
Title: Structure-guided development of affinity probes for tyrosine kinases using chemical genetics.
Journal: Nature chemical biology 20070401
Title: EGF receptor activity modulates apoptosis induced by inhibition of the proteasome of vascular smooth muscle cells.
Journal: Journal of the American Society of Nephrology : JASN 20070101
Title: Multitarget-directed drug design strategy: a novel molecule designed to block epidermal growth factor receptor (EGFR) and to exert proapoptotic effects.
Journal: Journal of medicinal chemistry 20061116
Title: Role of a tyrosine kinase in the CO2-induced stimulation of HCO3- reabsorption by rabbit S2 proximal tubules.
Journal: American journal of physiology. Renal physiology 20060801
Title: Interplay between epidermal growth factor receptor and Janus kinase 3 regulates polychlorinated biphenyl-induced matrix metalloproteinase-3 expression and transendothelial migration of tumor cells.
Journal: Molecular cancer research : MCR 20060601
Title: Epidermal growth factor receptor inhibitor (PD168393) potentiates cytotoxic effects of paclitaxel against androgen-independent prostate cancer cells.
Journal: Biochemical pharmacology 20060314
Title: Synthesis and structure-activity relationships of 6,7-disubstituted 4-anilinoquinoline-3-carbonitriles. The design of an orally active, irreversible inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor-2 (HER-2).
Journal: Journal of medicinal chemistry 20030102
Title: 6-Substituted-4-(3-bromophenylamino)quinazolines as putative irreversible inhibitors of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor (HER-2) tyrosine kinases with enhanced antitumor activity.
Journal: Journal of medicinal chemistry 20010816
Title: Tyrosine kinase inhibitors. 18. 6-Substituted 4-anilinoquinazolines and 4-anilinopyrido[3,4-d]pyrimidines as soluble, irreversible inhibitors of the epidermal growth factor receptor.
Journal: Journal of medicinal chemistry 20010201
Title: Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides bearing additional solubilizing functions.
Journal: Journal of medicinal chemistry 20000406
Title: D W Fry, et al. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):12022-7.