Home Thiazoles 2682-49-7
2682-49-7,MFCD01332388
Catalog No.:AA00BBHT

2682-49-7 | Thiazolidin-2-one

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5g
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10g
97%
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$8.00   $6.00
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25g
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100g
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
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  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00BBHT
Chemical Name:
Thiazolidin-2-one
CAS Number:
2682-49-7
Molecular Formula:
C3H5NOS
Molecular Weight:
103.1429
MDL Number:
MFCD01332388
SMILES:
C1CSC(=O)N1
NSC Number:
122613
Properties
Computed Properties
 
Complexity:
73.2  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
XLogP3:
0.3  

Upstream Synthesis Route

[1]Patent:WO2007/138072,2007,A2,.Locationinpatent:Page/Pagecolumn80

Downstream Synthesis Route

[1]JournaloftheAmericanChemicalSociety,1956,vol.78,p.5349

dithiocarbonicacid<i>S</i>-(2-amino-ethylester)-<i>S'</i>-methylester;hydrochloride 
  2682-49-7 

[1]JournaloftheChemicalSociety,1952,p.3094,3098,3102

[1]JournaloftheChemicalSociety,1952,p.3094,3098,3102

[1]JustusLiebigsAnnalenderChemie,1958,vol.614,p.83,94

[1]IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1982,vol.21,p.1115-1117

Literature

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Title: Synthesis and antimicrobial evaluation of some new thiazole, thiazolidinone and thiazoline derivatives starting from 1-chloro-3,4-dihydronaphthalene-2-carboxaldehyde.

Journal: European journal of medicinal chemistry 20070701

Title: Synthesis and biological evaluation of thiazolidine-2-one 1,1-dioxide as inhibitors of Escherichia coli beta-ketoacyl-ACP-synthase III (FabH).

Journal: Bioorganic & medicinal chemistry letters 20070215

Title: Latrunculin analogues with improved biological profiles by 'diverted total synthesis': preparation, evaluation, and computational analysis.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

Title: Anticancer activity of 5-benzylidene-2-phenylimino-1, 3-thiazolidin-4-one (BPT) analogs.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20061101

Title: Synthesis and in vitro antitumor evaluation of some indeno[1,2-c]pyrazol(in)es substituted with sulfonamide, sulfonylurea(-thiourea) pharmacophores, and some derived thiazole ring systems.

Journal: Bioorganic & medicinal chemistry 20061001

Title: Synthesis and anticonvulsant activity of some potential thiazolidinonyl 2-oxo/thiobarbituric acids.

Journal: European journal of medicinal chemistry 20061001

Title: Synthesis and pharmacological activity of 2-(substituted)-3-{2-[(4-phenyl-4-cyano)piperidino]ethyl}-1,3-thiazolidin-4-ones.

Journal: Chemical biology & drug design 20060601

Title: Allosteric activation of the follicle-stimulating hormone (FSH) receptor by selective, nonpeptide agonists.

Journal: The Journal of biological chemistry 20060512

Title: Microwave assisted synthesis of fragrant jasmone heterocyclic analogues.

Journal: European journal of medicinal chemistry 20060501

Title: Diversity of Cl(-) channels.

Journal: Cellular and molecular life sciences : CMLS 20060101

Title: CFTR chloride channel drug discovery--inhibitors as antidiarrheals and activators for therapy of cystic fibrosis.

Journal: Current pharmaceutical design 20060101

Title: Evidence that CFTR is expressed in rat tracheal smooth muscle cells and contributes to bronchodilation.

Journal: Respiratory research 20060101

Title: Structure-based discovery of inhibitors of the YycG histidine kinase: new chemical leads to combat Staphylococcus epidermidis infections.

Journal: BMC microbiology 20060101

Title: Preparation of highly substituted gamma-lactam follicle stimulating hormone receptor agonists.

Journal: Bioorganic & medicinal chemistry 20051101

Title: Synthesis of new 4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine derivatives with an incorporated thiazolidinone moiety and testing their possible serine protease and cercarial elastase inhibitory effects with a possible prospective to block penetration of Schistosoma mansoni cercariae into the mice skin.

Journal: Archives of pharmacal research 20050901

Title: Anti-microbial activity and film characterization of thiazolidinone derivatives of chitosan.

Journal: Macromolecular bioscience 20050624

Title: Discovery of 2-arylthiazolidine-4-carboxylic acid amides as a new class of cytotoxic agents for prostate cancer.

Journal: Journal of medicinal chemistry 20050407

Title: Antidiabetic and adipogenic properties in a newly synthesized thiazolidine derivative, FPFS-410.

Journal: Metabolism: clinical and experimental 20041201

Title: Syntheses and evaluation of antioxidant activity of sydnonyl substituted thiazolidinone and thiazoline derivatives.

Journal: Bioorganic & medicinal chemistry 20040901

Title: Effects of a new cystic fibrosis transmembrane conductance regulator inhibitor on Cl- conductance in human sweat ducts.

Journal: Experimental physiology 20040701

Title: A new dimension to the biosynthetic products isolated from the sponge Negombata magnifica.

Journal: Journal of natural products 20040601

Title: Agonists of the follicle stimulating hormone receptor from an encoded thiazolidinone library.

Journal: Journal of combinatorial chemistry 20040101

Title: Synthesis of some thiazolyl and thiadiazolyl derivatives of 4(3H)-quinazolinone as anti-inflammatory-antimicrobial agents.

Journal: Bollettino chimico farmaceutico 20040101

Title: Tetrazolo[1,5-a] quinoline derivatives as anti-inflammatory and antimicrobial agents [1].

Journal: Bollettino chimico farmaceutico 20040101

Title: Synthesis and biological evaluations of sulfa derivatives bearing heterocyclic moieties.

Journal: Bollettino chimico farmaceutico 20040101

Title: Synthesis and fungicidal activity of novel 4,4'-bis(2' '-aryl-5' '-methyl/unsubstituted-4' '-oxo-thiazolidin-3' '-yl) bibenzyl.

Journal: Journal of agricultural and food chemistry 20031119

Title: Synthesis of some new thiazole derivatives of pharmaceutical interest.

Journal: Bollettino chimico farmaceutico 20031101

Title: Synthesis and biological investigations of new thiazolidinone and oxadiazoline coumarin derivatives.

Journal: Archives of pharmacal research 20030901

Title: [5-Benzyl-3-phenyl-2-(2-pyridyl-kappaN)thiazolidin-4-one-kappaS]dichloropalladium(II).

Journal: Acta crystallographica. Section C, Crystal structure communications 20021201

Title: [New substituted 4-thioxothiazolidin-2-one derivatives: synthesis and structural study].

Journal: Annales pharmaceutiques francaises 20021101

Title: A new synthesis of oxadiazole, thiazolidinone, N-phthalimidoamino carbonyl and arylidene derivatives with potential antimicrobial activity.

Journal: Archiv der Pharmazie 20020601

Title: Synthesis of thiaazaheterocycle nucleoside analogues.

Journal: Nucleosides, nucleotides & nucleic acids 20020101

Title: Two thiazolino[2,3-a]isoquinolinone S-oxides.

Journal: Acta crystallographica. Section C, Crystal structure communications 20011201

Title: The reversed Kenner linker: a new safety-catch linker for the preparation of N-alkyl sulfonamides.

Journal: Organic letters 20010920

Title: Thiazolidine prodrugs as protective agents against gamma-radiation-induced toxicity and mutagenesis in V79 cells.

Journal: Journal of medicinal chemistry 20010802

Title: Synthesis and evaluation of the analgesic and antiinflammatory activities of O-substituted salicylamides.

Journal: Archives of pharmacal research 20010601

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Tags:2682-49-7 Molecular Formula|2682-49-7 MDL|2682-49-7 SMILES|2682-49-7 Thiazolidin-2-one |Heterocyclic_Building_Blocks