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254109-20-1,MFCD03453541
Catalog No.:AA00BCGU

254109-20-1 | DAF-FM

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1mg
>98%
1 week  
$1,097.00   $768.00
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5mg
>98%
1 week  
$3,570.00   $2,499.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BCGU
Chemical Name:
DAF-FM
CAS Number:
254109-20-1
Molecular Formula:
C21H14F2N2O5
Molecular Weight:
412.3431
MDL Number:
MFCD03453541
SMILES:
CNc1ccc2c(c1N)C(=O)OC12c2cc(F)c(cc2Oc2c1cc(F)c(c2)O)O
Properties
Computed Properties
 
Complexity:
668  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
1  
XLogP3:
3.5  

Literature

Title: The vasodilatory effect of testosterone on renal afferent arterioles.

Journal: Gender medicine 20120401

Title: Relaxin induces rapid dilation of rodent small renal and human subcutaneous arteries via PI3 kinase and nitric oxide.

Journal: Endocrinology 20110701

Title: Chronic intermittent hypoxia induces NMDA receptor-dependent plasticity and suppresses nitric oxide signaling in the mouse hypothalamic paraventricular nucleus.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100908

Title: Short-term type 1 diabetes alters the mechanism of endothelium-dependent relaxation in the rat carotid artery.

Journal: American journal of physiology. Heart and circulatory physiology 20100801

Title: Morphine prevents the mitochondrial permeability transition pore opening through NO/cGMP/PKG/Zn2+/GSK-3beta signal pathway in cardiomyocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20100201

Title: Endogenous nitric oxide is a key promoting factor for initiation of seizure-like events in hippocampal and entorhinal cortex slices.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090701

Title: Phenylephrine-induced cardiomyocyte injury is triggered by superoxide generation through uncoupled endothelial nitric-oxide synthase and ameliorated by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxyindazole (DY-9836), a novel calmodulin antagonist.

Journal: Molecular pharmacology 20090101

Title: T cells cooperate with palmitic acid in induction of beta cell apoptosis.

Journal: BMC immunology 20090101

Title: Endothelial cell-derived nitric oxide mobilization is attenuated in copper-deficient rats.

Journal: Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20081201

Title: Estrogen and the Ca2+-mobilizing agonist ATP evoke acute NO synthesis via distinct pathways in an individual human vascular endothelium-derived cell.

Journal: American journal of physiology. Cell physiology 20080601

Title: Measuring NO production by plant tissues and suspension cultured cells.

Journal: Molecular plant 20080301

Title: Regulation of endothelial nitric oxide synthase: involvement of protein kinase G 1 beta, serine 116 phosphorylation and lipid structures.

Journal: Clinical and experimental pharmacology & physiology 20080201

Title: Postconditioning prevents reperfusion injury by activating delta-opioid receptors.

Journal: Anesthesiology 20080201

Title: Small- and intermediate-conductance Ca2+-activated K+ channels directly control agonist-evoked nitric oxide synthesis in human vascular endothelial cells.

Journal: American journal of physiology. Cell physiology 20070701

Title: Glucose, insulin, and leptin signaling pathways modulate nitric oxide synthesis in glucose-inhibited neurons in the ventromedial hypothalamus.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070401

Title: Aspects of programmed cell death during early senescence of barley leaves: possible role of nitric oxide.

Journal: Protoplasma 20070101

Title: Opioid receptor-independent protection of ischemic rat hepatocytes by morphine.

Journal: Biochemical and biophysical research communications 20061229

Title: Impaired shear stress-induced nitric oxide production through decreased NOS phosphorylation contributes to age-related vascular stiffness.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20061201

Title: iNOS initiates and sustains metabolic arrest in hypoxic lung adenocarcinoma cells: mechanism of cell survival in solid tumor core.

Journal: American journal of physiology. Cell physiology 20051001

Title: On the specificity of 4-amino-5-methylamino-2',7'-difluorofluorescein as a probe for nitric oxide.

Journal: Free radical biology & medicine 20050801

Title: The novel red-fluorescent probe DAR-4M measures reactive nitrogen species rather than NO.

Journal: Journal of pharmacological and toxicological methods 20050101

Title: alpha-keto-beta-methyl-n-valeric acid diminishes reactive oxygen species and alters endoplasmic reticulum Ca(2+) stores.

Journal: Free radical biology & medicine 20041201

Title: Nitrite generates an oxidant stress and increases nitric oxide in EA.hy926 endothelial cells.

Journal: Free radical research 20040601

Title: Redox activity associated with the maturation and capacitation of mammalian spermatozoa.

Journal: Free radical biology & medicine 20040415

Title: Nitric oxide-mediated signaling in the bystander response of individually targeted glioma cells.

Journal: Cancer research 20031201

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