315-22-0,MFCD00084656
Catalog No.:AA00BY83

315-22-0 | Monocrotaline

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50mg
≥98%
in stock  
$89.00   $62.00
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100mg
≥98%
in stock  
$165.00   $115.00
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250mg
98%
in stock  
$214.00   $150.00
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500mg
≥98%
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1g
98%
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  • Technical Information
  • Properties
  • Literature
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Technical Information
Catalog Number:
AA00BY83
Chemical Name:
Monocrotaline
CAS Number:
315-22-0
Molecular Formula:
C16H23NO6
Molecular Weight:
325.3569
MDL Number:
MFCD00084656
SMILES:
O=C1O[C@@H]2CCN3[C@@H]2C(=CC3)COC(=O)[C@]([C@]([C@H]1C)(C)O)(C)O
Properties
Properties
 
Form:
Solid  
MP:
>140°C (dec.)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
575  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
XLogP3:
-0.7  

Literature

Title: Liquiritigenin and liquiritin alleviated MCT-induced HSOS by activating Nrf2 antioxidative defense system.

Journal: Toxicology and applied pharmacology 20180915

Title: Integrative analysis of hepatic microRNA and mRNA to identify potential biological pathways associated with monocrotaline-induced liver injury in mice.

Journal: Toxicology and applied pharmacology 20171015

Title: Serum microRNA-122-3p, microRNA-194-5p and microRNA-5099 are potential toxicological biomarkers for the hepatotoxicity induced by Airpotato yam.

Journal: Toxicology letters 20171005

Title: Galectin-3 contributes to vascular fibrosis in monocrotaline-induced pulmonary arterial hypertension rat model.

Journal: Journal of biochemical and molecular toxicology 20170501

Title: Comparative Study of Hepatotoxicity of Pyrrolizidine Alkaloids Retrorsine and Monocrotaline.

Journal: Chemical research in toxicology 20170220

Title: Comparative gene and protein expression analyses of a panel of cytokines in acute and chronic drug-induced liver injury in rats.

Journal: Toxicology 20141003

Title: Caveolin-1 is a negative regulator of NADPH oxidase-derived reactive oxygen species.

Journal: Free radical biology & medicine 20140801

Title: NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20140801

Title: Metabolomic analysis of arginine metabolism in acute hepatic injury in rats.

Journal: The Journal of toxicological sciences 20140201

Title: Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action.

Journal: PloS one 20140101

Title: The flavonoid quercetin reverses pulmonary hypertension in rats.

Journal: PloS one 20140101

Title: Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important role in its hepatotoxicity.

Journal: Toxicology 20130915

Title: Tissue factor antisense deoxyoligonucleotide prevents monocrotaline/LPS hepatotoxicity in mice.

Journal: Journal of applied toxicology : JAT 20130801

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: Sorafenib attenuates monocrotaline-induced sinusoidal obstruction syndrome in rats through suppression of JNK and MMP-9.

Journal: Journal of hepatology 20121101

Title: Bortezomib alleviates experimental pulmonary arterial hypertension.

Journal: American journal of respiratory cell and molecular biology 20121101

Title: Superiority of desflurane over sevoflurane and isoflurane in the presence of pressure-overload right ventricle hypertrophy in rats.

Journal: Anesthesiology 20121101

Title: Immune and inflammatory cell involvement in the pathology of idiopathic pulmonary arterial hypertension.

Journal: American journal of respiratory and critical care medicine 20121101

Title: Beneficial effects of γ-aminobutyric acid on right ventricular pressure and pulmonary vascular remodeling in experimental pulmonary hypertension.

Journal: Life sciences 20121015

Title: Comparison of metabolism-mediated effects of pyrrolizidine alkaloids in a HepG2/C3A cell-S9 co-incubation system and quantification of their glutathione conjugates.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20121001

Title: A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents.

Journal: American journal of respiratory and critical care medicine 20121001

Title: Dysregulated renin-angiotensin-aldosterone system contributes to pulmonary arterial hypertension.

Journal: American journal of respiratory and critical care medicine 20121001

Title: Benzenesulfonamide attenuates monocrotaline-induced pulmonary arterial hypertension in a rat model.

Journal: European journal of pharmacology 20120905

Title: Cardiac and vascular atrogin-1 mRNA expression is not associated with dexamethasone efficacy in the monocrotaline model of pulmonary hypertension.

Journal: Cardiovascular toxicology 20120901

Title: Plumbagin reverses proliferation and resistance to apoptosis in experimental PAH.

Journal: The European respiratory journal 20120901

Title: Atorvastatin prevents dehydromonocrotaline-induced pulmonary hypertension in beagles.

Journal: Experimental lung research 20120901

Title: Impaired natural killer cell phenotype and function in idiopathic and heritable pulmonary arterial hypertension.

Journal: Circulation 20120828

Title: Enhanced Ca(2+)-sensing receptor function in idiopathic pulmonary arterial hypertension.

Journal: Circulation research 20120803

Title: Attenuation of monocrotaline-induced pulmonary arterial hypertension in rats by rosuvastatin.

Journal: Journal of cardiovascular pharmacology 20120801

Title: Genistein, a soy phytoestrogen, reverses severe pulmonary hypertension and prevents right heart failure in rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20120801

Title: Caveolin-1 expression during the progression of pulmonary hypertension.

Journal: Experimental biology and medicine (Maywood, N.J.) 20120801

Title: The flavonoid monoHER prevents monocrotaline-induced hepatic sinusoidal injury in rats.

Journal: Journal of surgical oncology 20120701

Title: Effects of purple grape juice in the redox-sensitive modulation of right ventricular remodeling in a pulmonary arterial hypertension model.

Journal: Journal of cardiovascular pharmacology 20120701

Title: The Rho kinase inhibitor azaindole-1 has long-acting vasodilator activity in the pulmonary vascular bed of the intact chest rat.

Journal: Canadian journal of physiology and pharmacology 20120701

Title: Reverse right ventricular structural and extracellular matrix remodeling by estrogen in severe pulmonary hypertension.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20120701

Title: Effect of chronic sodium nitrite therapy on monocrotaline-induced pulmonary hypertension.

Journal: Nitric oxide : biology and chemistry 20120630

Title: Haemodynamic and neuroendocrine effects of tezosentan in chronic experimental pulmonary hypertension.

Journal: Intensive care medicine 20120601

Title: Cardiac arrhythmia mechanisms in rats with heart failure induced by pulmonary hypertension.

Journal: American journal of physiology. Heart and circulatory physiology 20120601

Title: Role of Src tyrosine kinases in experimental pulmonary hypertension.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20120601

Title: Changes of gene expression after bone marrow cell transfusion in rats with monocrotaline-induced pulmonary hypertension.

Journal: Journal of Korean medical science 20120601

Title: [Pathological changes of monocrotaline-induced pulmonary hypertension in miniature pigs].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120601

Title: Combined effects of the ATP-sensitive potassium channel opener pinacidil and simvastatin on pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.

Journal: Die Pharmazie 20120601

Title: Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.

Journal: Circulation research 20120525

Title: Mechanical load-dependent cardiac ER stress in vitro and in vivo: effects of preload and afterload.

Journal: FEBS letters 20120507

Title: Implantation of mesenchymal stem cells improves right ventricular impairments caused by experimental pulmonary hypertension.

Journal: The American journal of the medical sciences 20120501

Title: Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology 20120501

Title: [Pathophysiological characteristics of rat pulmonary hypertension and cor pulmonale induced by monocrotaline].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20120501

Title: Oxygen radicals and substance P in perinatal hypoxia-exaggerated, monocrotaline-induced pulmonary hypertension.

Journal: The Chinese journal of physiology 20120430

Title: Effects of 2-azafluorenones on phosphatidyl-inositol specific phospholipase C activation in c6 glioma cells.

Journal: The Chinese journal of physiology 20120430

Title: PAR-2 inhibition reverses experimental pulmonary hypertension.

Journal: Circulation research 20120427

Title: Cardiac-specific genetic inhibition of nuclear factor-κB prevents right ventricular hypertrophy induced by monocrotaline.

Journal: American journal of physiology. Heart and circulatory physiology 20120415

Title: Dehydropyrrolizidine alkaloids, including monoesters with an unusual esterifying acid, from cultivated Crotalaria juncea (Sunn Hemp cv.'Tropic Sun').

Journal: Journal of agricultural and food chemistry 20120411

Title: Fluoxetine protects against monocrotaline-induced pulmonary arterial remodeling by inhibition of hypoxia-inducible factor-1α and vascular endothelial growth factor.

Journal: Canadian journal of physiology and pharmacology 20120401

Title: Angiotensin-converting enzyme 2 activation protects against pulmonary arterial hypertension through improving early endothelial function and mediating cytokines levels.

Journal: Chinese medical journal 20120401

Title: Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1.

Journal: Cardiovascular research 20120315

Title: Lung ¹⁸F-fluorodeoxyglucose positron emission tomography for diagnosis and monitoring of pulmonary arterial hypertension.

Journal: American journal of respiratory and critical care medicine 20120315

Title: Effects of everolimus in combination with sildenafil in monocrotaline-induced pulmonary hypertension in rats.

Journal: Cardiovascular toxicology 20120301

Title: Mast cell inhibition improves pulmonary vascular remodeling in pulmonary hypertension.

Journal: Chest 20120301

Title: Attenuation of the extract from Moringa oleifera on monocrotaline-induced pulmonary hypertension in rats.

Journal: The Chinese journal of physiology 20120227

Title: The monocrotaline model of pulmonary hypertension in perspective.

Journal: American journal of physiology. Lung cellular and molecular physiology 20120215

Title: Targeted gene delivery of BMPR2 attenuates pulmonary hypertension.

Journal: The European respiratory journal 20120201

Title: Spontaneous ventricular fibrillation in right ventricular failure secondary to chronic pulmonary hypertension.

Journal: Circulation. Arrhythmia and electrophysiology 20120201

Title: Sildenafil prevents and reverses transverse-tubule remodeling and Ca(2+) handling dysfunction in right ventricle failure induced by pulmonary artery hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20120201

Title: Year in review in Intensive Care Medicine 2011: I. Nephrology, epidemiology, nutrition and therapeutics, neurology, ethical and legal issues, experimentals.

Journal: Intensive care medicine 20120201

Title: [Genistein attenuates monocrotaline-induced pulmonary arterial hypertension in rats by up-regulating heme oxygenase-1 expression].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120201

Title: Factor VIII can be synthesized in hemophilia A mice liver by bone marrow progenitor cell-derived hepatocytes and sinusoidal endothelial cells.

Journal: Stem cells and development 20120101

Title: Transgenic expression of human matrix metalloproteinase-1 attenuates pulmonary arterial hypertension in mice.

Journal: Clinical science (London, England : 1979) 20120101

Title: Fibrosis of pulmonary vascular remodeling in carotid artery-jugular vein shunt pulmonary artery hypertension model of rats.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20120101

Title: Enhanced store-operated Ca²+ entry and TRPC channel expression in pulmonary arteries of monocrotaline-induced pulmonary hypertensive rats.

Journal: American journal of physiology. Cell physiology 20120101

Title: Development and characterization of an animal model of severe pulmonary arterial hypertension.

Journal: Journal of vascular research 20120101

Title: Regional skeletal muscle remodeling and mitochondrial dysfunction in right ventricular heart failure.

Journal: American journal of physiology. Heart and circulatory physiology 20120101

Title: Resveratrol reverses monocrotaline-induced pulmonary vascular and cardiac dysfunction: a potential role for atrogin-1 in smooth muscle.

Journal: Vascular pharmacology 20120101

Title: Bisoprolol delays progression towards right heart failure in experimental pulmonary hypertension.

Journal: Circulation. Heart failure 20120101

Title: TGFβ signaling and cardiovascular diseases.

Journal: International journal of biological sciences 20120101

Title: Effects of autologous bone marrow mononuclear cells implantation in canine model of pulmonary hypertension.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: New cardiovascular and pulmonary therapeutic strategies based on the Angiotensin-converting enzyme 2/angiotensin-(1-7)/mas receptor axis.

Journal: International journal of hypertension 20120101

Title: Independent recruitment of a flavin-dependent monooxygenase for safe accumulation of sequestered pyrrolizidine alkaloids in grasshoppers and moths.

Journal: PloS one 20120101

Title: Chronic allergic inflammation causes vascular remodeling and pulmonary hypertension in BMPR2 hypomorph and wild-type mice.

Journal: PloS one 20120101

Title: Comparative potential therapeutic effect of sesame oil and peanut oil against acute monocrotaline (Crotalaria) poisoning in a rat model.

Journal: Journal of veterinary internal medicine 20120101

Title: Relation of bosentan, iloprost, and sildenafil with growth factor levels in monocrotaline-induced pulmonary hypertension.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20120101

Title: Liver disorders in inflammatory bowel disease.

Journal: Gastroenterology research and practice 20120101

Title: Nicorandil attenuates monocrotaline-induced vascular endothelial damage and pulmonary arterial hypertension.

Journal: PloS one 20120101

Title: Early treatment with fumagillin, an inhibitor of methionine aminopeptidase-2, prevents Pulmonary Hypertension in monocrotaline-injured rats.

Journal: PloS one 20120101

Title: Targeting the adventitial microenvironment in pulmonary hypertension: A potential approach to therapy that considers epigenetic change.

Journal: Pulmonary circulation 20120101

Title: Serum osteoprotegerin is increased and predicts survival in idiopathic pulmonary arterial hypertension.

Journal: Pulmonary circulation 20120101

Title: Identification of functional progenitor cells in the pulmonary vasculature.

Journal: Pulmonary circulation 20120101

Title: Smooth muscle myosin inhibition: a novel therapeutic approach for pulmonary hypertension.

Journal: PloS one 20120101

Title: Acute effects of vardenafil on pulmonary artery responsiveness in pulmonary hypertension.

Journal: TheScientificWorldJournal 20120101

Title: Longitudinal in vivo SPECT/CT imaging reveals morphological changes and cardiopulmonary apoptosis in a rodent model of pulmonary arterial hypertension.

Journal: PloS one 20120101

Title: Activation of the unfolded protein response is associated with pulmonary hypertension.

Journal: Pulmonary circulation 20120101

Title: The Role of Astrocytes in Metabolism and Neurotoxicity of the Pyrrolizidine Alkaloid Monocrotaline, the Main Toxin of Crotalaria retusa.

Journal: Frontiers in pharmacology 20120101

Title: Comparison of two experimental models of pulmonary hypertension.

Journal: Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 20120101

Title: Nicorandil prevents right ventricular remodeling by inhibiting apoptosis and lowering pressure overload in rats with pulmonary arterial hypertension.

Journal: PloS one 20120101

Title: Assessment of neurotoxicity of monocrotaline, an alkaloid extracted from Crotalaria retusa in astrocyte/neuron co-culture system.

Journal: Neurotoxicology 20111201

Title: Association of the time course of pulmonary arterial hypertension with changes in oxidative stress in the left ventricle.

Journal: Clinical and experimental pharmacology & physiology 20111201

Title: Morphological aspects of neuromuscular junctions and gene expression of nicotinic acetylcholine receptors (nAChRs) in skeletal muscle of rats with heart failure.

Journal: Journal of molecular histology 20111201

Title: C-122, a novel antagonist of serotonin receptor 5-HT2B, prevents monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: European journal of pharmacology 20111116

Title: Therapeutic sesamol attenuates monocrotaline-induced sinusoidal obstruction syndrome in rats by inhibiting matrix metalloproteinase-9.

Journal: Cell biochemistry and biophysics 20111101

Title: ¹H NMR study of monocrotaline and its metabolites in human blood.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111101

Title: Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension.

Journal: American journal of physiology. Heart and circulatory physiology 20111101

Title: Egr-1 expression during neointimal development in flow-associated pulmonary hypertension.

Journal: The American journal of pathology 20111101

Title: Evidence of diminished coronary flow in pulmonary hypertension: explaining angina pectoris in this patient group?

Journal: Clinical physiology and functional imaging 20111101

Title: Stem-cell therapy in an experimental model of pulmonary hypertension and right heart failure: role of paracrine and neurohormonal milieu in the remodeling process.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20111101

Title: Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease.

Journal: The Journal of clinical investigation 20111101

Title: Silencing of tissue factor by antisense deoxyoligonucleotide prevents monocrotaline/LPS renal injury in mice.

Journal: Archives of toxicology 20111001

Title: Matrix metalloproteinase-2 (MMP-2) and membrane-type 1 MMP (MT1-MMP) affect the remodeling of glomerulosclerosis in diabetic OLETF rats.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111001

Title: A role for coagulation factor Xa in experimental pulmonary arterial hypertension.

Journal: Cardiovascular research 20111001

Title: Advances in tenascin-C biology.

Journal: Cellular and molecular life sciences : CMLS 20111001

Title: Alteration of pulmonary artery integrin levels in chronic hypoxia and monocrotaline-induced pulmonary hypertension.

Journal: Journal of vascular research 20111001

Title: Simvastatin protects against the development of monocrotaline-induced pulmonary hypertension in rats via a heme oxygenase-1-dependent pathway.

Journal: Experimental lung research 20111001

Title: The relationship between structurally different pyrrolizidine alkaloids and western flower thrips resistance in F(2) hybrids of Jacobaea vulgaris and Jacobaea aquatica.

Journal: Journal of chemical ecology 20111001

Title: Influence of estrogen on pulmonary arterial hypertension: role of oxidative stress.

Journal: Cell biochemistry and function 20111001

Title: [Determination of pulmonary vascular resistance by improved right heart catheter in rat].

Journal: Zhonghua xin xue guan bing za zhi 20111001

Title: Efficacy of aminaftone in a rat model of monocrotaline-induced pulmonary hypertension.

Journal: European journal of pharmacology 20110930

Title: Estrogen rescues preexisting severe pulmonary hypertension in rats.

Journal: American journal of respiratory and critical care medicine 20110915

Title: Oxidized low-density lipoprotein and tissue factor are involved in monocrotaline/lipopolysaccharide-induced hepatotoxicity.

Journal: Archives of toxicology 20110901

Title: Aspirin attenuates pulmonary arterial hypertension in rats by reducing plasma 5-hydroxytryptamine levels.

Journal: Cell biochemistry and biophysics 20110901

Title: Rosuvastatin attenuates monocrotaline-induced pulmonary hypertension via regulation of Akt/eNOS signaling and asymmetric dimethylarginine metabolism.

Journal: European journal of pharmacology 20110901

Title: Intralipid prevents and rescues fatal pulmonary arterial hypertension and right ventricular failure in rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20110901

Title: Changes of pulmonary pathology and gene expressions after simvastatin treatment in the monocrotaline-induced pulmonary hypertension rat model.

Journal: Korean circulation journal 20110901

Title: Urantide alleviates monocrotaline induced pulmonary arterial hypertension in Wistar rats.

Journal: Pulmonary pharmacology & therapeutics 20110801

Title: Rapid quantification of myocardial fibrosis: a new macro-based automated analysis.

Journal: Cellular oncology (Dordrecht) 20110801

Title: Levosimendan attenuates pulmonary vascular remodeling.

Journal: Intensive care medicine 20110801

Title: Exacerbated pulmonary arterial hypertension and right ventricular hypertrophy in animals with loss of function of extracellular superoxide dismutase.

Journal: Hypertension (Dallas, Tex. : 1979) 20110801

Title: Rodent models of pulmonary hypertension: harmonisation with the world health organisation's categorisation of human PH.

Journal: International journal of clinical practice. Supplement 20110801

Title: Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension.

Journal: Journal of molecular medicine (Berlin, Germany) 20110801

Title: [Transplantation of marrow mesenchymal stem cells transfected with vascular endothelial growth factor gene for the treatment of pulmonary hypertension in rats].

Journal: Zhonghua yi xue za zhi 20110712

Title: Perivascular T-cell infiltration leads to sustained pulmonary artery remodeling after endothelial cell damage.

Journal: American journal of respiratory cell and molecular biology 20110701

Title: Treatment of pulmonary arterial hypertension with circulating angiogenic cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20110701

Title: Tissue factor dependent liver injury causes release of retinoid receptors (RXR-α and RAR-α) as lipid droplets.

Journal: Biochemical and biophysical research communications 20110624

Title: Mast cells promote lung vascular remodelling in pulmonary hypertension.

Journal: The European respiratory journal 20110601

Title: Arrhythmogenic substrate in hearts of rats with monocrotaline-induced pulmonary hypertension and right ventricular hypertrophy.

Journal: American journal of physiology. Heart and circulatory physiology 20110601

Title: Downregulation of osteopontin is associated with fluoxetine amelioration of monocrotaline-induced pulmonary inflammation and vascular remodelling.

Journal: Clinical and experimental pharmacology & physiology 20110601

Title: Dexamethasone attenuates development of monocrotaline-induced pulmonary arterial hypertension.

Journal: Molecular biology reports 20110601

Title: Differential morphofunctional characteristics and gene expression in fast and slow muscle of rats with monocrotaline-induced heart failure.

Journal: Journal of molecular histology 20110601

Title: Cytotoxicity of monocrotaline in isolated rat hepatocytes: effects of dithiothreitol and fructose.

Journal: Toxicon : official journal of the International Society on Toxinology 20110601

Title: Peptide-directed highly selective targeting of pulmonary arterial hypertension.

Journal: The American journal of pathology 20110601

Title: Diaphragm muscle fiber weakness in pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine 20110515

Title: Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats.

Journal: The European respiratory journal 20110501

Title: New perspectives for the treatment of pulmonary hypertension.

Journal: British journal of pharmacology 20110501

Title: Involvement of BMPR2 in the protective effect of fluoxetine against monocrotaline-induced endothelial apoptosis in rats.

Journal: Canadian journal of physiology and pharmacology 20110501

Title: [Studies on the alkaloids of Senecio scandens growing in Guangdong].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110501

Title: Impact of pulmonary vascular resistances in heart transplantation for congenital heart disease.

Journal: Current cardiology reviews 20110501

Title: Dexamethasone reverses monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: The European respiratory journal 20110401

Title: Suppression of tissue inhibitors of metalloproteinases may reverse severe pulmonary arterial hypertension.

Journal: Cytotherapy 20110401

Title: Role of Rho-kinase signaling and endothelial dysfunction in modulating blood flow distribution in pulmonary hypertension.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20110401

Title: Hepatocyte growth factor improves the survival of rats with pulmonary arterial hypertension via the amelioration of pulmonary hemodynamics.

Journal: International journal of molecular medicine 20110401

Title: Doppler flow spectra of the superior vena cava in a rat model of chronic pulmonary hypertension.

Journal: Laboratory animals 20110401

Title: Effects of simvastatin on pulmonary C-fiber sensitivity in rats with monocrotaline-induced pulmonary hypertension.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20110301

Title: Pulmonary and systemic vasodilator responses to the soluble guanylyl cyclase activator, BAY 60-2770, are not dependent on endogenous nitric oxide or reduced heme.

Journal: American journal of physiology. Heart and circulatory physiology 20110301

Title: [Effects of rosuvastatin on monocrotaline-induced pulmonary artery hypertension in rats].

Journal: Zhonghua xin xue guan bing za zhi 20110301

Title: [Evaluation of vitro hepatotoxicity of monocrotaline by precision-cut liver slice technique].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110301

Title: [Simultaneous quantitation of adonifoline and senecionine in Senecio herbs by UPLC-MS].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110301

Title: Right ventricular failure following chronic pressure overload is associated with reduction in left ventricular mass: evidence for atrophic remodeling.

Journal: Journal of the American College of Cardiology 20110222

Title: Transgenic expression of human matrix metalloproteinase-9 augments monocrotaline-induced pulmonary arterial hypertension in mice.

Journal: Journal of hypertension 20110201

Title: Fluoxetine inhibited extracellular matrix of pulmonary artery and inflammation of lungs in monocrotaline-treated rats.

Journal: Acta pharmacologica Sinica 20110201

Title: Nanoparticle-mediated delivery of pitavastatin into lungs ameliorates the development and induces regression of monocrotaline-induced pulmonary artery hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20110201

Title: Emerging pathogenetic mechanisms of pulmonary arterial hypertension: nitric oxide and more.

Journal: Korean circulation journal 20110201

Title: Gene expressions of nitric oxide synthase and matrix metalloproteinase-2 in monocrotaline-induced pulmonary hypertension in rats after bosentan treatment.

Journal: Korean circulation journal 20110201

Title: [Toxicity of monocrotaline on in vitro cultured mouse embryos].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110201

Title: The effects of antiangiogenic compound SU5416 in a rat model of pulmonary arterial hypertension.

Journal: Respiration; international review of thoracic diseases 20110101

Title: Perturbations in ataxia telangiectasia mutant signaling pathways after drug-induced acute liver failure and their reversal during rescue of animals by cell therapy.

Journal: The American journal of pathology 20110101

Title: Pressure load: the main factor for altered gene expression in right ventricular hypertrophy in chronic hypoxic rats.

Journal: PloS one 20110101

Title: Placenta growth factor and vascular endothelial growth factor B expression in the hypoxic lung.

Journal: Respiratory research 20110101

Title: The protective effects of cerium oxide nanoparticles against hepatic oxidative damage induced by monocrotaline.

Journal: International journal of nanomedicine 20110101

Title: Protective effects of hydrogen-rich saline on monocrotaline-induced pulmonary hypertension in a rat model.

Journal: Respiratory research 20110101

Title: Ang-(1-7) might prevent the development of monocrotaline induced pulmonary arterial hypertension in rats.

Journal: European review for medical and pharmacological sciences 20110101

Title: Role of the gap junctions in the contractile response to agonists in pulmonary artery from two rat models of pulmonary hypertension.

Journal: Respiratory research 20110101

Title: Acceleration of Ca2+ waves in monocrotaline-induced right ventricular hypertrophy in the rat.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101

Title: [A sharp increase in the density of pulmonary and pericardial mast cells under monocrotaline-induced pulmonary hypertension in rats].

Journal: Tsitologiia 20110101

Title: Prospect of vasoactive intestinal peptide therapy for COPD/PAH and asthma: a review.

Journal: Respiratory research 20110101

Title: Phosphodiesterase 10A upregulation contributes to pulmonary vascular remodeling.

Journal: PloS one 20110101

Title: Pulmonary arterial dysfunction in insulin resistant obese Zucker rats.

Journal: Respiratory research 20110101

Title: Glycogen synthase kinase 3beta contributes to proliferation of arterial smooth muscle cells in pulmonary hypertension.

Journal: PloS one 20110101

Title: MicroRNA let-7f inhibits tumor invasion and metastasis by targeting MYH9 in human gastric cancer.

Journal: PloS one 20110101

Title: Involvement of mast cells in monocrotaline-induced pulmonary hypertension in rats.

Journal: Respiratory research 20110101

Title: Recent trends in pulmonary arterial hypertension.

Journal: Lung India : official organ of Indian Chest Society 20110101

Title: Cell-specific dual role of caveolin-1 in pulmonary hypertension.

Journal: Pulmonary medicine 20110101

Title: Therapeutic strategies in pulmonary hypertension.

Journal: Frontiers in pharmacology 20110101

Title: ACE2 improves right ventricular function in a pressure overload model.

Journal: PloS one 20110101

Title: What is new for an old molecule? Systematic review and recommendations on the use of resveratrol.

Journal: PloS one 20110101

Title: Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension.

Journal: Respiratory research 20110101

Title: Novel interventional approaches for ALI/ARDS: cell-based gene therapy.

Journal: Mediators of inflammation 20110101

Title: Angiogenesis gene expression in murine endothelial cells during post-pneumonectomy lung growth.

Journal: Respiratory research 20110101

Title: Hypoxia-inducible factor-1 α/platelet derived growth factor axis in HIV-associated pulmonary vascular remodeling.

Journal: Respiratory research 20110101

Title: Pulmonary oxidative stress is increased in cyclooxygenase-2 knockdown mice with mild pulmonary hypertension induced by monocrotaline.

Journal: PloS one 20110101

Title: Increased oxidative stress and severe arterial remodeling induced by permanent high-flow challenge in experimental pulmonary hypertension.

Journal: Respiratory research 20110101

Title: Krüppel-like factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension.

Journal: Respiratory research 20110101

Title: Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells.

Journal: Respiratory research 20110101

Title: VIP and endothelin receptor antagonist: an effective combination against experimental pulmonary arterial hypertension.

Journal: Respiratory research 20110101

Title: Progenitor cells in pulmonary vascular remodeling.

Journal: Pulmonary circulation 20110101

Title: Protein trafficking dysfunctions: Role in the pathogenesis of pulmonary arterial hypertension.

Journal: Pulmonary circulation 20110101

Title: Combination use of sildenafil and simvastatin increases BMPR-II signal transduction in rats with monocrotaline-mediated pulmonary hypertension.

Journal: Pulmonary circulation 20110101

Title: Transgenic mice over-expressing ET-1 in the endothelial cells develop systemic hypertension with altered vascular reactivity.

Journal: PloS one 20110101

Title: Xanthine oxidase-derived ROS upregulate Egr-1 via ERK1/2 in PA smooth muscle cells; model to test impact of extracellular ROS in chronic hypoxia.

Journal: PloS one 20110101

Title: The genetics of pulmonary arterial hypertension in the post-BMPR2 era.

Journal: Pulmonary circulation 20110101

Title: Apelin and pulmonary hypertension.

Journal: Pulmonary circulation 20110101

Title: Epigenetic mechanisms of pulmonary hypertension.

Journal: Pulmonary circulation 20110101

Title: MicroRNAs-control of essential genes: Implications for pulmonary vascular disease.

Journal: Pulmonary circulation 20110101

Title: Pharmacogenomics in pulmonary arterial hypertension: Toward a mechanistic, target-based approach to therapy.

Journal: Pulmonary circulation 20110101

Title: Development of pulmonary arterial hypertension in mice over-expressing S100A4/Mts1 is specific to females.

Journal: Respiratory research 20110101

Title: Treatment with LA-419 prevents monocrotaline-induced pulmonary hypertension and lung injury in the rat.

Journal: Proceedings of the Western Pharmacology Society 20110101

Title: Reversible or irreversible remodeling in pulmonary arterial hypertension.

Journal: American journal of respiratory cell and molecular biology 20101201

Title: Gene delivery of cytochrome p450 epoxygenase ameliorates monocrotaline-induced pulmonary artery hypertension in rats.

Journal: American journal of respiratory cell and molecular biology 20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Urotensin II receptor antagonist attenuates monocrotaline-induced cardiac hypertrophy in rats.

Journal: American journal of physiology. Heart and circulatory physiology 20101201

Title: [Comparison of the hepatic veno-occlusive disease models induced by gynura segetum, monocrotaline and cyclophosphamide].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20101201

Title: Simvastatin, sildenafil and their combination in monocrotaline induced pulmonary arterial hypertension.

Journal: Korean circulation journal 20101201

Title: Innate immunity in the therapeutic actions of endothelial progenitor cells in pulmonary hypertension.

Journal: American journal of respiratory cell and molecular biology 20101101

Title: Effects of atorvastatin and L-arginine treatments on electrical field stimulation-mediated relaxations in pulmonary arterial rings of monocrotaline-induced pulmonary hypertensive rats.

Journal: Journal of cardiovascular pharmacology 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Synergistic therapeutic effects of 2-methoxyestradiol with either sildenafil or bosentan on amelioration of monocrotaline-induced pulmonary hypertension and vascular remodeling.

Journal: Journal of cardiovascular pharmacology 20101101

Title: Effects of HIV protease inhibitors on progression of monocrotaline- and hypoxia-induced pulmonary hypertension in rats.

Journal: Circulation 20101101

Title: Contribution of oxidative stress to pulmonary arterial hypertension.

Journal: World journal of cardiology 20101026

Title: The angiotensin-converting enzyme 2/angiogenesis-(1-7)/Mas axis confers cardiopulmonary protection against lung fibrosis and pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine 20101015

Title: Combination of sildenafil and simvastatin ameliorates monocrotaline-induced pulmonary hypertension in rats.

Journal: Pulmonary pharmacology & therapeutics 20101001

Title: Fasudil reduces monocrotaline-induced pulmonary arterial hypertension: comparison with bosentan and sildenafil.

Journal: The European respiratory journal 20101001

Title: Downregulation of oxytocin receptors in right ventricle of rats with monocrotaline-induced pulmonary hypertension.

Journal: Acta physiologica (Oxford, England) 20101001

Title: Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension.

Journal: The European respiratory journal 20101001

Title: The effects of atorvastatin on pulmonary arterial hypertension and expression of p38, p27, and Jab1 in rats.

Journal: International journal of molecular medicine 20101001

Title: Differential cellular responses to protein adducts of naphthoquinone and monocrotaline pyrrole.

Journal: Chemical research in toxicology 20100920

Title: Adrenergic receptor blockade reverses right heart remodeling and dysfunction in pulmonary hypertensive rats.

Journal: American journal of respiratory and critical care medicine 20100901

Title: Analysis of heart rate variability in a rat model of induced pulmonary hypertension.

Journal: Medical engineering & physics 20100901

Title: Validation of high-resolution echocardiography and magnetic resonance imaging vs. high-fidelity catheterization in experimental pulmonary hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology 20100901

Title: Developing and characterizing a mouse model of hepatotoxicity using oral pyrrolizidine alkaloid (monocrotaline) administration, with potentiation of the liver injury by co-administration of LPS.

Journal: Natural product communications 20100901

Title: Drug off-target effects predicted using structural analysis in the context of a metabolic network model.

Journal: PLoS computational biology 20100901

Title: Gene expression of endothelin-1 and endothelin receptor a on monocrotaline-induced pulmonary hypertension in rats after bosentan treatment.

Journal: Korean circulation journal 20100901

Title: Skeletal muscle proteins oxidation in chronic right heart failure in rats: can different beta-blockers prevent it to the same degree?

Journal: International journal of cardiology 20100820

Title: Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension.

Journal: Science translational medicine 20100811

Title: PRX-08066, a novel 5-hydroxytryptamine receptor 2B antagonist, reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20100801

Title: Consistency of predictive signature genes and classifiers generated using different microarray platforms.

Journal: The pharmacogenomics journal 20100801

Title: Smad-dependent and smad-independent induction of id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo.

Journal: Circulation research 20100723

Title: Determination of endothelin-1 in rats using a high-performance liquid chromatography coupled to electrospray tandem mass spectrometry.

Journal: Talanta 20100715

Title: Analysis of responses to the Rho-kinase inhibitor Y-27632 in the pulmonary and systemic vascular bed of the rat.

Journal: American journal of physiology. Heart and circulatory physiology 20100701

Title: Early inflammatory response during the development of right ventricular heart failure in a rat model.

Journal: European journal of heart failure 20100701

Title: Smurf1 ubiquitin ligase causes downregulation of BMP receptors and is induced in monocrotaline and hypoxia models of pulmonary arterial hypertension.

Journal: Experimental biology and medicine (Maywood, N.J.) 20100701

Title: A comparison of echocardiography to invasive measurement in the evaluation of pulmonary arterial hypertension in a rat model.

Journal: The international journal of cardiovascular imaging 20100601

Title: L-arginine restores endothelial nitric oxide synthase-coupled activity and attenuates monocrotaline-induced pulmonary artery hypertension in rats.

Journal: American journal of physiology. Endocrinology and metabolism 20100601

Title: Sildenafil limits monocrotaline-induced pulmonary hypertension in rats through suppression of pulmonary vascular remodeling.

Journal: Journal of cardiovascular pharmacology 20100601

Title: The xanthine derivative KMUP-1 inhibits models of pulmonary artery hypertension via increased NO and cGMP-dependent inhibition of RhoA/Rho kinase.

Journal: British journal of pharmacology 20100601

Title: KMUP-1 ameliorates monocrotaline-induced pulmonary arterial hypertension through the modulation of Ca2+ sensitization and K+-channel.

Journal: Life sciences 20100508

Title: Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats.

Journal: Basic research in cardiology 20100501

Title: Gene expression profile in flow-associated pulmonary arterial hypertension with neointimal lesions.

Journal: American journal of physiology. Lung cellular and molecular physiology 20100401

Title: Pulmonary hypertension is ameliorated in mice deficient in thrombin-activatable fibrinolysis inhibitor.

Journal: Journal of thrombosis and haemostasis : JTH 20100401

Title: Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20100401

Title: Reduced mechanical efficiency of rat papillary muscle related to degree of hypertrophy of cardiomyocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20100401

Title: Sodium valproate, a histone deacetylase inhibitor, but not captopril, prevents right ventricular hypertrophy in rats.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20100401

Title: High-performance liquid chromatography electrospray ionization tandem mass spectrometry for the detection and quantitation of pyrrolizidine alkaloid-derived DNA adducts in vitro and in vivo.

Journal: Chemical research in toxicology 20100315

Title: Glucuronidation, a new metabolic pathway for pyrrolizidine alkaloids.

Journal: Chemical research in toxicology 20100315

Title: Cardiomyocyte-specific inactivation of thyroid hormone in pathologic ventricular hypertrophy: an adaptative response or part of the problem?

Journal: Heart failure reviews 20100301

Title: Antioxidant treatment attenuates pulmonary arterial hypertension-induced heart failure.

Journal: American journal of physiology. Heart and circulatory physiology 20100301

Title: A high-calorie diet attenuates cachexia and adipose tissue inflammation in monocrotaline-induced pulmonary hypertensive rats.

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20100301

Title: [TRPC6 mediates the enhancements of pulmonary arterial tone and intracellular Ca2+ concentration of pulmonary arterial smooth muscle cells in pulmonary hypertension rats].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20100225

Title: Resveratrol inhibits right ventricular hypertrophy induced by monocrotaline in rats.

Journal: Clinical and experimental pharmacology & physiology 20100201

Title: Impaired vasoconstriction and nitric oxide-mediated relaxation in pulmonary arteries of hypoxia- and monocrotaline-induced pulmonary hypertensive rats.

Journal: The Journal of pharmacology and experimental therapeutics 20100201

Title: The enzymatic degradation of hyaluronan is associated with disease progression in experimental pulmonary hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology 20100201

Title: Progressive endothelial cell damage in an inflammatory model of pulmonary hypertension.

Journal: Experimental lung research 20100201

Title: Heart failure increases atrogin-1 and MuRF1 gene expression in skeletal muscle with fiber type-specific atrophy.

Journal: Journal of molecular histology 20100201

Title: Ghrelin and cardiovascular diseases.

Journal: Current cardiology reviews 20100201

Title: Role of epidermal growth factor inhibition in experimental pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine 20100115

Title: Retrorsine, but not monocrotaline, is a mechanism-based inactivator of P450 3A4.

Journal: Chemico-biological interactions 20100105

Title: Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase-dependent nitric oxide generation.

Journal: Circulation 20100105

Title: The effects and mechanisms of mycophenolate mofetil on pulmonary arterial hypertension in rats.

Journal: Rheumatology international 20100101

Title: Poisoning of sheep by seeds of Crotalaria retusa: acquired resistance by continuous administration of low doses.

Journal: Toxicon : official journal of the International Society on Toxinology 20100101

Title: Genotoxicity and morphological changes induced by the alkaloid monocrotaline, extracted from Crotalaria retusa, in a model of glial cells.

Journal: Toxicon : official journal of the International Society on Toxinology 20100101

Title: Modulation of monocrotaline-induced cor pulmonale by grape juice.

Journal: Journal of cardiovascular pharmacology 20100101

Title: The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle.

Journal: Journal of molecular medicine (Berlin, Germany) 20100101

Title: Pulmonary hemodynamic response to acute combination and monotherapy with sildenafil and brain natriuretic peptide in rats with monocrotaline-induced pulmonary hypertension.

Journal: The American journal of the medical sciences 20100101

Title: The extracellular signal-regulated kinase is involved in the effects of sildenafil on pulmonary vascular remodeling.

Journal: Cardiovascular therapeutics 20100101

Title: Polyamine regulatory pathways as pharmacologic targets in pulmonary arterial hypertension.

Journal: Advances in experimental medicine and biology 20100101

Title: The PPARbeta/delta agonist GW0742 relaxes pulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension.

Journal: PloS one 20100101

Title: Novel approaches to treat experimental pulmonary arterial hypertension: a review.

Journal: Journal of biomedicine & biotechnology 20100101

Title: Estrogen-induced relaxation of the rat tail artery is attenuated in rats with pulmonary hypertension.

Journal: Pharmacological reports : PR 20100101

Title: Idiopathic pulmonary arterial hypertension.

Journal: Disease models & mechanisms 20100101

Title: Flavin-dependent monooxygenases as a detoxification mechanism in insects: new insights from the arctiids (lepidoptera).

Journal: PloS one 20100101

Title: Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELM alpha) recruits bone marrow-derived cells to the murine pulmonary vasculature.

Journal: PloS one 20100101

Title: Dose-dependent therapeutic effects of 2-Methoxyestradiol on Monocrotaline-Induced pulmonary hypertension and vascular remodelling.

Journal: Prilozi 20100101

Title: Involvement of asymmetric dimethylarginine and Rho kinase in the vascular remodeling in monocrotaline-induced pulmonary hypertension.

Journal: Vascular pharmacology 20100101

Title: KMUP-1 inhibits pulmonary artery proliferation by targeting serotonin receptors/transporter and NO synthase, inactivating RhoA and suppressing AKT/ERK phosphorylation.

Journal: Vascular pharmacology 20100101

Title: Systemic evaluation of platelet and leukocyte activation and interaction in a rat model of pulmonary arterial hypertension.

Journal: Cardiology 20100101

Title: Genetics of pulmonary arterial hypertension: do the molecular findings have translational value?

Journal: F1000 biology reports 20100101

Title: Rapid quantification of myocardial fibrosis: A new macro-based automated analysis.

Journal: Analytical cellular pathology (Amsterdam) 20100101

Title: Interleukin-6 as a potential therapeutic target for pulmonary arterial hypertension.

Journal: International journal of rheumatology 20100101

Title: Diesel engine exhaust initiates a sequence of pulmonary and cardiovascular effects in rats.

Journal: Journal of toxicology 20100101

Title: Transforming growth factor-β inhibition attenuates pulmonary arterial hypertension in rats.

Journal: International journal of clinical and experimental medicine 20100101

Title: Effects of atorvastatin and losartan on monocrotaline-induced pulmonary artery remodeling in rats.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20100101

Title: Biochemistry and occurrence of o-demethylation in plant metabolism.

Journal: Frontiers in physiology 20100101

Title: Ayurveda and cancer.

Journal: Pharmacognosy research 20100101

Title: Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure.

Journal: American journal of physiology. Lung cellular and molecular physiology 20091201

Title: Effects of a pure alpha/beta-adrenergic receptor blocker on monocrotaline-induced pulmonary arterial hypertension with right ventricular hypertrophy in rats.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20091201

Title: Alterations in dystrophin-related glycoproteins in development of right ventricular failure in rats.

Journal: Journal of pharmacological sciences 20091201

Title: Identification of genomic biomarkers for concurrent diagnosis of drug-induced renal tubular injury using a large-scale toxicogenomics database.

Journal: Toxicology 20091109

Title: Senescent endothelial progenitor cells from dogs with pulmonary arterial hypertension: a before-after self-controlled study.

Journal: The journal of physiological sciences : JPS 20091101

Title: Right ventricular pacing improves right heart function in experimental pulmonary arterial hypertension: a study in the isolated heart.

Journal: American journal of physiology. Heart and circulatory physiology 20091101

Title: Allogenic stem cell therapy improves right ventricular function by improving lung pathology in rats with pulmonary hypertension.

Journal: American journal of physiology. Heart and circulatory physiology 20091101

Title: Tadalafil, a long-acting inhibitor of PDE5, improves pulmonary hemodynamics and survival rate of monocrotaline-induced pulmonary artery hypertension in rats.

Journal: Journal of pharmacological sciences 20091101

Title: [Testosterone therapy improves cardiac function of male rats with right heart failure].

Journal: Zhonghua nan ke xue = National journal of andrology 20091101

Title: Intracellular glutathione plays important roles in pyrrolizidine alkaloids-induced growth inhibition on hepatocytes.

Journal: Environmental toxicology and pharmacology 20091101

Title: Evaluation of the simvastatin effects in the treatment of pulmonary hypertension (PH).

Journal: Lijecnicki vjesnik 20091101

Title: Golgi, trafficking, and mitosis dysfunctions in pulmonary arterial endothelial cells exposed to monocrotaline pyrrole and NO scavenging.

Journal: American journal of physiology. Lung cellular and molecular physiology 20091001

Title: Effects of telmisartan on right ventricular remodeling induced by monocrotaline in rats.

Journal: Journal of pharmacological sciences 20091001

Title: Time course and mechanisms of left ventricular systolic and diastolic dysfunction in monocrotaline-induced pulmonary hypertension.

Journal: Basic research in cardiology 20090901

Title: Cirrhosis ameliorates monocrotaline-induced pulmonary hypertension in rats.

Journal: The European respiratory journal 20090901

Title: Early combined treatment with cilostazol and bone marrow-derived endothelial progenitor cells markedly attenuates pulmonary arterial hypertension in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20090901

Title: Is resveratrol the magic bullet for pulmonary hypertension?

Journal: Hypertension (Dallas, Tex. : 1979) 20090901

Title: Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20090901

Title: Propylthiouracil attenuates monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20090901

Title: Possible involvement of mitochondrial energy-producing ability in the development of right ventricular failure in monocrotaline-induced pulmonary hypertensive rats.

Journal: Journal of pharmacological sciences 20090901

Title: Feeding deterrence and detrimental effects of pyrrolizidine alkaloids fed to honey bees (Apis mellifera).

Journal: Journal of chemical ecology 20090901

Title: Monocrotaline-induced pulmonary hypertension in Wistar rats.

Journal: Current protocols in pharmacology 20090901

Title: [Administrating bone marrow mesenchymal stem cells to treat the experimental pulmonary arterial hypertension in rats].

Journal: Zhonghua yi xue za zhi 20090811

Title: Fluoxetine protects against monocrotaline-induced pulmonary arterial hypertension: potential roles of induction of apoptosis and upregulation of Kv1.5 channels in rats.

Journal: Clinical and experimental pharmacology & physiology 20090801

Title: Bone marrow progenitor cells repair rat hepatic sinusoidal endothelial cells after liver injury.

Journal: Gastroenterology 20090801

Title: Continuous fluoxetine administration prevents recurrence of pulmonary arterial hypertension and prolongs survival in rats.

Journal: Clinical and experimental pharmacology & physiology 20090801

Title: Change in pharmacological effect of endothelin receptor antagonists in rats with pulmonary hypertension: role of ETB-receptor expression levels.

Journal: Pulmonary pharmacology & therapeutics 20090801

Title: Prevention of pulmonary hypertension by Angiotensin-converting enzyme 2 gene transfer.

Journal: Hypertension (Dallas, Tex. : 1979) 20090801

Title: Serial noninvasive assessment of apoptosis during right ventricular disease progression in rats.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090801

Title: Syngeneic bone marrow mononuclear cells improve pulmonary arterial hypertension through vascular endothelial growth factor upregulation.

Journal: The Annals of thoracic surgery 20090801

Title: Alterations in pharmacological action of the right ventricle of monocrotaline-induced pulmonary hypertensive rats.

Journal: Biological & pharmaceutical bulletin 20090801

Title: Retraction. Reliable experimental model of hepatic veno-occlusive disease caused by monocrotaline.

Journal: Hepatobiliary & pancreatic diseases international : HBPD INT 20090801

Title: Temporal changes of angiopoietins and Tie2 expression in rat lungs after monocrotaline-induced pulmonary hypertension.

Journal: Comparative medicine 20090801

Title: Discriminating pulmonary hypertension caused by monocrotaline toxicity from chronic hypoxia by near-infrared spectroscopy and multivariate methods of analysis.

Journal: Analytical biochemistry 20090715

Title: Opposite effects of training in rats with stable and progressive pulmonary hypertension.

Journal: Circulation 20090707

Title: Dehydromonocrotaline induces cyclosporine A-insensitive mitochondrial permeability transition/cytochrome c release.

Journal: Toxicon : official journal of the International Society on Toxinology 20090701

Title: Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension in rats.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20090701

Title: Analysis of pulmonary vasodilator responses to SB-772077-B [4-(7-((3-amino-1-pyrrolidinyl)carbonyl)-1-ethyl-1H-imidazo(4,5-c)pyridin-2-yl)-1,2,5-oxadiazol-3-amine], a novel aminofurazan-based Rho kinase inhibitor.

Journal: The Journal of pharmacology and experimental therapeutics 20090701

Title: Effects of pyrrolizidine alkaloids on the performance of plant-parasitic and free-living nematodes.

Journal: Pest management science 20090701

Title: Preventive effects of raloxifene, a selective estrogen receptor modulator, on monocrotaline-induced pulmonary hypertension in intact and ovariectomized female rats.

Journal: European journal of pharmacology 20090701

Title: Effects of roflumilast, a phosphodiesterase-4 inhibitor, on hypoxia- and monocrotaline-induced pulmonary hypertension in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20090701

Title: Endothelin receptor blockade combined with phosphodiesterase-5 inhibition increases right ventricular mitochondrial capacity in pulmonary arterial hypertension.

Journal: American journal of physiology. Heart and circulatory physiology 20090701

Title: Changes in pulmonary blood flow distribution in monocrotaline compared with hypoxia-induced models of pulmonary hypertension: assessed using synchrotron radiation.

Journal: Journal of hypertension 20090701

Title: Molecular imaging of monocrotaline-induced pulmonary vascular disease with radiolabeled linear adrenomedullin.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090701

Title: [B-type natriuretic peptide (BNP) levels and the effects of carvedilol on BNP levels in juvenile rats with right heart failure].

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20090701

Title: Progesterone inhibits vascular remodeling and attenuates monocrotaline-induced pulmonary hypertension in estrogen-deficient rats.

Journal: Prilozi 20090701

Title: Marrow cell infusion attenuates vascular remodeling in a murine model of monocrotaline-induced pulmonary hypertension.

Journal: Stem cells and development 20090601

Title: Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine 20090601

Title: Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension.

Journal: American journal of physiology. Heart and circulatory physiology 20090601

Title: Hepatic regeneration is decreased in a rat model of sinusoidal obstruction syndrome.

Journal: Journal of surgical oncology 20090601

Title: Cardiac lesions induced by testosterone: protective effects of dexrazoxane and trimetazidine.

Journal: Cardiovascular toxicology 20090601

Title: A novel therapeutic strategy for liver sinusoidal obstruction syndrome.

Journal: Journal of gastroenterology and hepatology 20090601

Title: Dai-kenchu-to attenuates rat sinusoidal obstruction syndrome by inhibiting the accumulation of neutrophils in the liver.

Journal: Journal of gastroenterology and hepatology 20090601

Title: Establishment of rat model of cardiopulmonary bypass in pulmonary hypertension.

Journal: Asian cardiovascular & thoracic annals 20090601

Title: Simvastatin restores down-regulated GATA-6 expression in pulmonary hypertensive rats.

Journal: Experimental lung research 20090601

Title: Nanoparticle-mediated delivery of nuclear factor kappaB decoy into lungs ameliorates monocrotaline-induced pulmonary arterial hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20090501

Title: A phosphodiesterase III inhibitor protects rat liver from sinusoidal obstruction syndrome through heme oxygenase-1 induction.

Journal: Annals of surgery 20090501

Title: Chronic inhibition of phosphodiesterase 5 does not prevent pressure-overload-induced right-ventricular remodelling.

Journal: Cardiovascular research 20090401

Title: [Simvastatin prevents the development of pulmonary hypertension in the rats through reduction of inflammation].

Journal: Zhonghua yi xue za zhi 20090331

Title: Warning displays may function as honest signals of toxicity.

Journal: Proceedings. Biological sciences 20090307

Title: Galphaq-protein carboxyl terminus imitation polypeptide (GCIP)-27 inhibits right ventricular hypertrophy induced by monocrotaline in rats.

Journal: Biological & pharmaceutical bulletin 20090301

Title: Pulmonary hypertension modifies responsiveness of sinoatrial cells of rat hearts to adrenomimetics and activators of ATP-sensitive K+ channels in a gender-dependent way.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20090301

Title: Low doses of monocrotaline in rats cause diminished bone marrow cellularity and compromised nitric oxide production by peritoneal macrophages.

Journal: Journal of immunotoxicology 20090301

Title: 3-Hydroxy-3-methylglutaryl (HMG)-COA reductase inhibitors and phosphodiesterase type V inhibitors attenuate right ventricular pressure and remodeling in a rat model of pulmonary hypertension.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090204

Title: Altered bone morphogenetic protein and transforming growth factor-beta signaling in rat models of pulmonary hypertension: potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease.

Journal: Circulation 20090203

Title: CPU0213, a non-selective ETA/ETB receptor antagonist, improves pulmonary arteriolar remodeling of monocrotaline-induced pulmonary hypertension in rats.

Journal: Clinical and experimental pharmacology & physiology 20090201

Title: Molecular and electrical remodeling of L- and T-type Ca(2+) channels in rat right atrium with monocrotaline-induced pulmonary hypertension.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20090201

Title: Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by monocrotaline.

Journal: The American journal of pathology 20090201

Title: Inhibition of the soluble epoxide hydrolase attenuates monocrotaline-induced pulmonary hypertension in rats.

Journal: Journal of hypertension 20090201

Title: From arginine methylation to ADMA: a novel mechanism with therapeutic potential in chronic lung diseases.

Journal: BMC pulmonary medicine 20090101

Title: Characterization of erectile function in monocrotaline-treated pulmonary hypertensive rats.

Journal: Journal of andrology 20090101

Title: The remodeling of connexin in the hypertrophied right ventricular in pulmonary arterial hypertension and the effect of a dual ET receptor antagonist (bosentan).

Journal: Pathology, research and practice 20090101

Title: Self-medication as adaptive plasticity: increased ingestion of plant toxins by parasitized caterpillars.

Journal: PloS one 20090101

Title: Simvastatin ameliorates established pulmonary hypertension through a heme oxygenase-1 dependent pathway in rats.

Journal: Respiratory research 20090101

Title: Serum VEGF levels are related to the presence of pulmonary arterial hypertension in systemic sclerosis.

Journal: BMC pulmonary medicine 20090101

Title: Inhaled iloprost for the control of pulmonary hypertension.

Journal: Vascular health and risk management 20090101

Title: Discernment of possible mechanisms of hepatotoxicity via biological processes over-represented by co-expressed genes.

Journal: BMC genomics 20090101

Title: Divergent cardiopulmonary actions of heme oxygenase enzymatic products in chronic hypoxia.

Journal: PloS one 20090101

Title: Treatment of pediatric pulmonary hypertension.

Journal: Vascular health and risk management 20090101

Title: Caveolin-1 Expression and Hemodynamics in COPD Patients.

Journal: The open respiratory medicine journal 20090101

Title: Protective effects of hydroalcoholic extract from rhizomes of Cynodon dactylon (L.) Pers. on compensated right heart failure in rats.

Journal: BMC complementary and alternative medicine 20090101

Title: RhoA/Rho-kinase signaling: a therapeutic target in pulmonary hypertension.

Journal: Vascular health and risk management 20090101

Title: Pressure overload-induced right ventricular failure is associated with re-expression of myocardial tenascin-C and elevated plasma tenascin-C levels.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101

Title: Update on pulmonary hypertension complicating chronic obstructive pulmonary disease.

Journal: International journal of chronic obstructive pulmonary disease 20090101

Title: Inhibition of SOC/Ca2+/NFAT pathway is involved in the anti-proliferative effect of sildenafil on pulmonary artery smooth muscle cells.

Journal: Respiratory research 20090101

Title: Anti-TNF treatment reduces rat skeletal muscle wasting in monocrotaline-induced cardiac cachexia.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20081201

Title: Upregulation of GLUT-4 in right ventricle of rats with monocrotaline-induced pulmonary hypertension.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20081201

Title: Captopril attenuates matrix metalloproteinase-2 and -9 in monocrotaline-induced right ventricular hypertrophy in rats.

Journal: Journal of pharmacological sciences 20081201

Title: Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling.

Journal: Circulation 20081111

Title: Effects of monocrotaline on energy metabolism in the rat liver.

Journal: Toxicology letters 20081110

Title: Analysis of pulmonary vasodilator responses to the Rho-kinase inhibitor fasudil in the anesthetized rat.

Journal: American journal of physiology. Lung cellular and molecular physiology 20081101

Title: Endothelin-3-dependent pulmonary vasoconstriction in monocrotaline-induced pulmonary arterial hypertension.

Journal: Peptides 20081101

Title: Depletion of the ATPase NSF from Golgi membranes with hypo-S-nitrosylation of vasorelevant proteins in endothelial cells exposed to monocrotaline pyrrole.

Journal: American journal of physiology. Heart and circulatory physiology 20081101

Title: Hemin treatment abrogates monocrotaline-induced pulmonary hypertension.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20081101

Title: Novel approach with intratracheal administration of microgelatin hydrogel microspheres incorporating basic fibroblast growth factor for rescue of rats with monocrotaline-induced pulmonary hypertension.

Journal: The Journal of thoracic and cardiovascular surgery 20081101

Title: Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension.

Journal: British journal of pharmacology 20081001

Title: Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.

Journal: The European respiratory journal 20081001

Title: Effects of endogenous sulfur dioxide on monocrotaline-induced pulmonary hypertension in rats.

Journal: Acta pharmacologica Sinica 20081001

Title: m-Nisoldipine attenuates monocrotaline-induced pulmonary hypertension by suppressing 5-HT/ERK MAPK pathway.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20081001

Title: Involvement of Bcl-xL degradation and mitochondrial-mediated apoptotic pathway in pyrrolizidine alkaloids-induced apoptosis in hepatocytes.

Journal: Toxicology and applied pharmacology 20080915

Title: Thymulin inhibits monocrotaline-induced pulmonary hypertension modulating interleukin-6 expression and suppressing p38 pathway.

Journal: Endocrinology 20080901

Title: Celecoxib but not the combination of celecoxib+atorvastatin prevents the development of monocrotaline-induced pulmonary hypertension in the rat.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080901

Title: A long-acting and highly selective prostacyclin receptor agonist prodrug, 2-{4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide (NS-304), ameliorates rat pulmonary hypertension with unique relaxant responses of its active form, {4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}acetic acid (MRE-269), on rat pulmonary artery.

Journal: The Journal of pharmacology and experimental therapeutics 20080901

Title: Effects of a chronic exercise training protocol on oxidative stress and right ventricular hypertrophy in monocrotaline-treated rats.

Journal: Clinical and experimental pharmacology & physiology 20080801

Title: Monocrotaline pyrrol is cytotoxic and alters the patterns of GFAP expression on astrocyte primary cultures.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080801

Title: Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice.

Journal: American journal of physiology. Heart and circulatory physiology 20080801

Title: Total ginsenosides inhibit the right ventricular hypertrophy induced by monocrotaline in rats.

Journal: Biological & pharmaceutical bulletin 20080801

Title: Reliable experimental model of hepatic veno-occlusive disease caused by monocrotaline.

Journal: Hepatobiliary & pancreatic diseases international : HBPD INT 20080801

Title: Final report on carcinogens background document for riddelliine.

Journal: Report on carcinogens background document for [substance name] 20080801

Title: Role of the prostanoid EP4 receptor in iloprost-mediated vasodilatation in pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine 20080715

Title: Reduced number and activity of circulating endothelial progenitor cells in patients with idiopathic pulmonary arterial hypertension.

Journal: Respiratory medicine 20080701

Title: Involvement of RhoA/Rho kinase signaling in protection against monocrotaline-induced pulmonary hypertension in pneumonectomized rats by dehydroepiandrosterone.

Journal: American journal of physiology. Lung cellular and molecular physiology 20080701

Title: Pyrrolidine dithiocarbamate restores endothelial cell membrane integrity and attenuates monocrotaline-induced pulmonary artery hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology 20080601

Title: Down-regulation of MyoD gene expression in rat diaphragm muscle with heart failure.

Journal: International journal of experimental pathology 20080601

Title: Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, heliotrine.

Journal: Toxicology letters 20080505

Title: Skeletal muscle myofibrillar protein oxidation and exercise capacity in heart failure.

Journal: Basic research in cardiology 20080501

Title: Cilostazol therapy attenuates monocrotaline-induced pulmonary arterial hypertension in rat model.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20080501

Title: [Contribution of circulating platelet and leukocyte activation to primary pulmonary hypertension in rats].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20080501

Title: [Quantitative and functional changes of circulating endothelial progenitor cells in dogs with dehydromonocrotaline-induced pulmonary artery hypertension].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20080501

Title: [Expression of connective tissue growth factor and its down-regulation by simvastatin administration in pulmonary hypertensive rats].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20080501

Title: Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine 20080415

Title: Bone marrow progenitor cells contribute to repair and remodeling of the lung and heart in a rat model of progressive pulmonary hypertension.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080401

Title: Metabolic activation of retronecine and retronecine N-oxide - formation of DHP-derived DNA adducts.

Journal: Toxicology and industrial health 20080401

Title: Carnitine-mediated improved response to erythropoietin involves induction of haem oxygenase-1: studies in humans and in an animal model.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080301

Title: Partial reversal of experimental pulmonary hypertension by phosphodiesterase-3/4 inhibition.

Journal: The European respiratory journal 20080301

Title: Cytoplasmic provenance of STAT3 and PY-STAT3 in the endolysosomal compartments in pulmonary arterial endothelial and smooth muscle cells: implications in pulmonary arterial hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology 20080301

Title: Autologous transplantation of bone marrow-derived endothelial progenitor cells attenuates monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: Critical care medicine 20080301

Title: Pulmonary hypertension associated with COPD.

Journal: International journal of chronic obstructive pulmonary disease 20080301

Title: Effects of TNF-alpha blockade in monocrotaline-induced pulmonary hypertension.

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20080301

Title: A refined radio-telemetry technique to monitor right ventricle or pulmonary artery pressures in rats: a useful tool in pulmonary hypertension research.

Journal: Pflugers Archiv : European journal of physiology 20080201

Title: Rosuvastatin provides pleiotropic protection against pulmonary hypertension, right ventricular hypertrophy, and coronary endothelial dysfunction in rats.

Journal: American journal of physiology. Heart and circulatory physiology 20080201

Title: Smad signaling in the rat model of monocrotaline pulmonary hypertension.

Journal: Toxicologic pathology 20080201

Title: Gene transfer of extracellular superoxide dismutase ameliorates pulmonary hypertension in rats.

Journal: American journal of respiratory and critical care medicine 20080115

Title: Single injection of a sustained-release prostacyclin analog improves pulmonary hypertension in rats.

Journal: American journal of respiratory and critical care medicine 20080115

Title: Effects of erythropoietin on advanced pulmonary vascular remodelling.

Journal: The European respiratory journal 20080101

Title: Hepatocyte transplantation and drug-induced perturbations in liver cell compartments.

Journal: Hepatology (Baltimore, Md.) 20080101

Title: Evaluation of olmesartan medoxomil in the rat monocrotaline model of pulmonary hypertension.

Journal: Journal of cardiovascular pharmacology 20080101

Title: 2-Ethoxyestradiol is antimitogenic and attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling.

Journal: Vascular pharmacology 20080101

Title: Rho kinase-mediated vasoconstriction in rat models of pulmonary hypertension.

Journal: Methods in enzymology 20080101

Title: CD45RB is a novel molecular therapeutic target to inhibit Abeta peptide-induced microglial MAPK activation.

Journal: PloS one 20080101

Title: Genes related to apoptosis predict necrosis of the liver as a phenotype observed in rats exposed to a compendium of hepatotoxicants.

Journal: BMC genomics 20080101

Title: Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype.

Journal: Genome biology 20080101

Title: Effects of selective and unselective endothelin-receptor antagonists on prostacyclin synthase gene expression in experimental pulmonary hypertension.

Journal: Scandinavian journal of clinical and laboratory investigation 20080101

Title: Biomarkers for ragwort poisoning in horses: identification of protein targets.

Journal: BMC veterinary research 20080101

Title: Gene set enrichment analysis for non-monotone association and multiple experimental categories.

Journal: BMC bioinformatics 20080101

Title: Use of bioluminescent imaging to assay the transplantation of immortalized human fetal hepatocytes into mice.

Journal: Cell transplantation 20080101

Title: Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury.

Journal: BMC pulmonary medicine 20080101

Title: [Comparative characteristics of some pharmacological models of chronic heart failure].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20080101

Title: In vitro metabolism of isoline, a pyrrolizidine alkaloid from Ligularia duciformis, by rodent liver microsomal esterase and enhanced hepatotoxicity by esterase inhibitors.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20071001

Title: Dehydromonocrotaline inhibits mitochondrial complex I. A potential mechanism accounting for hepatotoxicity of monocrotaline.

Journal: Toxicon : official journal of the International Society on Toxinology 20071001

Title: Oral sildenafil prevents and reverses the development of pulmonary hypertension in monocrotaline-treated rats.

Journal: Interactive cardiovascular and thoracic surgery 20071001

Title: Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study.

Journal: American journal of physiology. Lung cellular and molecular physiology 20071001

Title: The antiproliferative effect of sildenafil on pulmonary artery smooth muscle cells is mediated via upregulation of mitogen-activated protein kinase phosphatase-1 and degradation of extracellular signal-regulated kinase 1/2 phosphorylation.

Journal: Anesthesia and analgesia 20071001

Title: A nuclear factor-kappaB inhibitor pyrrolidine dithiocarbamate ameliorates pulmonary hypertension in rats.

Journal: Chest 20071001

Title: [Effect of triptolide on the expression of matrix metalloproteinases 2 and 9 in lungs of experimental pulmonary hypertension].

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20071001

Title: Interleukin-10 expression mediated by an adeno-associated virus vector prevents monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: Circulation research 20070928

Title: Serotonin transporter protein in pulmonary hypertensive rats treated with atorvastatin.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070901

Title: Right-ventricular failure is associated with increased mitochondrial complex II activity and production of reactive oxygen species.

Journal: Cardiovascular research 20070901

Title: Plexiform-like lesions and increased tissue factor expression in a rat model of severe pulmonary arterial hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070901

Title: Preservation of diastolic function in monocrotaline-induced right ventricular hypertrophy in rats.

Journal: American journal of physiology. Heart and circulatory physiology 20070901

Title: Adenoassociated virus-mediated prostacyclin synthase expression prevents pulmonary arterial hypertension in rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20070901

Title: Rodent models of PAH: are we there yet?

Journal: American journal of physiology. Lung cellular and molecular physiology 20070901

Title: Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1.

Journal: PLoS medicine 20070901

Title: [Effect of triptolide on the development of monocrotaline-induced pulmonary hypertension in pneumonectomized rat].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070901

Title: Protective effect of Adhatoda vascia Nees against radiation-induced damage at cellular, biochemical and chromosomal levels in Swiss albino mice.

Journal: Evidence-based complementary and alternative medicine : eCAM 20070901

Title: Early changes in rat hearts with developing pulmonary arterial hypertension can be detected with three-dimensional electrocardiography.

Journal: American journal of physiology. Heart and circulatory physiology 20070801

Title: Effects of combined therapy with a Rho-kinase inhibitor and prostacyclin on monocrotaline-induced pulmonary hypertension in rats.

Journal: Journal of cardiovascular pharmacology 20070801

Title: Frequency-dependent myofilament Ca2+ desensitization in failing rat myocardium.

Journal: The Journal of physiology 20070715

Title: Dysfunctional intracellular trafficking in the pathobiology of pulmonary arterial hypertension.

Journal: American journal of respiratory cell and molecular biology 20070701

Title: Decreased left ventricular function, myocarditis, and coronary arteriolar medial thickening following monocrotaline administration in adult rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20070701

Title: Pulmonary arterial hypertension: a disease of tethers, SNAREs and SNAPs?

Journal: American journal of physiology. Heart and circulatory physiology 20070701

Title: Amlodipine prevents monocrotaline-induced pulmonary arterial hypertension and prolongs survival in rats independent of blood pressure lowering.

Journal: Clinical and experimental pharmacology & physiology 20070701

Title: Comparison of lung proteome profiles in two rodent models of pulmonary arterial hypertension.

Journal: Proteomics 20070701

Title: Cardiac sympathetic rejuvenation: a link between nerve function and cardiac hypertrophy.

Journal: Circulation research 20070622

Title: Impaired NO-mediated vasodilation with increased superoxide but robust EDHF function in right ventricular arterial microvessels of pulmonary hypertensive rats.

Journal: American journal of physiology. Heart and circulatory physiology 20070601

Title: Roles of accumulated endogenous nitric oxide synthase inhibitors, enhanced arginase activity, and attenuated nitric oxide synthase activity in endothelial cells for pulmonary hypertension in rats.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070601

Title: Monocrotaline pyrrole induces Smad nuclear accumulation and altered signaling expression in human pulmonary arterial endothelial cells.

Journal: Vascular pharmacology 20070601

Title: Dysfunction of Golgi tethers, SNAREs, and SNAPs in monocrotaline-induced pulmonary hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070601

Title: The transforming growth factor-beta/Smad2,3 signalling axis is impaired in experimental pulmonary hypertension.

Journal: The European respiratory journal 20070601

Title: [Changes of pulmonary artery protein kinase C activity in rats with chronic inflammatory pulmonary hypertension].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070601

Title: [Effect of simvastatin on rat pulmonary hypertension induced by high pulmonary blood flow and injected monocrotaline].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070601

Title: Inhibitory effect of ginsenoside Rb1 on cardiac hypertrophy induced by monocrotaline in rat.

Journal: Journal of ethnopharmacology 20070522

Title: Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20070501

Title: [Expression and activity of RhoA/Rho kinase in remodeling of high blood flow pulmonary vessels.].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20070501

Title: Overexpression of human bone morphogenetic protein receptor 2 does not ameliorate monocrotaline pulmonary arterial hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070401

Title: Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070401

Title: Recent progress in the treatment of pulmonary arterial hypertension: expectation for rho-kinase inhibitors.

Journal: The Tohoku journal of experimental medicine 20070401

Title: [Animal models of pulmonary arterial hypertension].

Journal: Revue des maladies respiratoires 20070401

Title: [Changes of thrombomodulin in rats with pulmonary hypertension induced by monocrotaline].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20070401

Title: Aberrant cytoplasmic sequestration of eNOS in endothelial cells after monocrotaline, hypoxia, and senescence: live-cell caveolar and cytoplasmic NO imaging.

Journal: American journal of physiology. Heart and circulatory physiology 20070301

Title: Dendritic cell recruitment in lesions of human and experimental pulmonary hypertension.

Journal: The European respiratory journal 20070301

Title: Internalization and dephosphorylation of connexin43 in hypertrophied right ventricles of rats with pulmonary hypertension.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20070301

Title: Bone marrow-derived hepatic oval cells differentiate into hepatocytes in 2-acetylaminofluorene/partial hepatectomy-induced liver regeneration.

Journal: Gastroenterology 20070301

Title: [Pulmonary hypertension treatment: future prospects].

Journal: Archivos de bronconeumologia 20070301

Title: Intratracheal mesenchymal stem cell administration attenuates monocrotaline-induced pulmonary hypertension and endothelial dysfunction.

Journal: American journal of physiology. Heart and circulatory physiology 20070201

Title: Acute vasodilator effect of fasudil, a Rho-kinase inhibitor, in monocrotaline-induced pulmonary hypertension in rats.

Journal: Journal of cardiovascular pharmacology 20070201

Title: Diverse contribution of bone marrow-derived cells to vascular remodeling associated with pulmonary arterial hypertension and arterial neointimal formation.

Journal: Circulation 20070130

Title: Inhibition of rho kinase attenuates high flow induced pulmonary hypertension in rats.

Journal: Chinese medical journal 20070105

Title: Right ventricular hypertrophy causes impairment of left ventricular diastolic function in the rat.

Journal: Basic research in cardiology 20070101

Title: Propofol increases pulmonary vascular resistance during alpha-adrenoreceptor activation in normal and monocrotaline-induced pulmonary hypertensive rats.

Journal: Anesthesia and analgesia 20070101

Title: Granulocyte colony-stimulating factor prevents progression of monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20070101

Title: Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice.

Journal: Respiratory research 20070101

Title: Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice.

Journal: Respiratory research 20070101

Title: Activity of endothelium-derived hyperpolarizing factor is augmented in monocrotaline-induced pulmonary hypertension of rat lungs.

Journal: Journal of vascular research 20070101

Title: Effects on cytokines and histology by treatment with the ACE inhibitor captopril and the antioxidant retinoic acid in the monocrotaline model of experimentally induced lung fibrosis.

Journal: Current pharmaceutical design 20070101

Title: The role of peroxisome proliferator-activated receptors in pulmonary vascular disease.

Journal: PPAR research 20070101

Title: Characterisation of a rat model of pulmonary arterial hypertension.

Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20070101

Title: PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice.

Journal: BMC cell biology 20070101

Title: Activation of signaling molecules and matrix metalloproteinases in right ventricular myocardium of rats with pulmonary hypertension.

Journal: Pathology, research and practice 20070101

Title: Comparison of gene expression profiles altered by comfrey and riddelliine in rat liver.

Journal: BMC bioinformatics 20070101

Title: Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats.

Journal: BMC bioinformatics 20070101

Title: [Chronic administration of serotonin transporter inhibitor (fluoxetine) decreases monocrotaline-induced pulmonary hypertension in rats].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20070101

Title: [Chronic blockade of serotonin transporter promotes restoration of the sensitivity of pulmonary vessels to vasoconstrictive agents in rats with monocrotaline-induced pulmonary hypertension].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20070101

Title: Modeling inflammation-drug interactions in vitro: a rat Kupffer cell-hepatocyte coculture system.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20061201

Title: 2-Methoxyestradiol mediates the protective effects of estradiol in monocrotaline-induced pulmonary hypertension.

Journal: Vascular pharmacology 20061201

Title: Sleeping Beauty-mediated eNOS gene therapy attenuates monocrotaline-induced pulmonary hypertension in rats.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20061201

Title: The protective effect of HMG-CoA reductase inhibitors against monocrotaline-induced pulmonary hypertension in the rat might not be a class effect: comparison of pravastatin and atorvastatin.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20061201

Title: Monocrotaline promotes transplanted cell engraftment and advances liver repopulation in rats via liver conditioning.

Journal: Hepatology (Baltimore, Md.) 20061201

Title: Heart failure alters matrix metalloproteinase gene expression and activity in rat skeletal muscle.

Journal: International journal of experimental pathology 20061201

Title: Sildenafil in the treatment of pulmonary hypertension.

Journal: Vascular health and risk management 20061201

Title: Prostacyclin therapy increases right ventricular capillarisation in a model for flow-associated pulmonary hypertension.

Journal: European journal of pharmacology 20061107

Title: Allicin in garlic protects against coronary endothelial dysfunction and right heart hypertrophy in pulmonary hypertensive rats.

Journal: American journal of physiology. Heart and circulatory physiology 20061101

Title: Characterization of right ventricular function after monocrotaline-induced pulmonary hypertension in the intact rat.

Journal: American journal of physiology. Heart and circulatory physiology 20061101

Title: Sertraline protects against monocrotaline-induced pulmonary hypertension in rats.

Journal: Clinical and experimental pharmacology & physiology 20061101

Title: Protective role of protein C inhibitor in monocrotaline-induced pulmonary hypertension.

Journal: Journal of thrombosis and haemostasis : JTH 20061101

Title: Treprostinil in advanced experimental pulmonary hypertension: beneficial outcome without reversed pulmonary vascular remodeling.

Journal: Journal of cardiovascular pharmacology 20061101

Title: [Expression of GATA6 gene in lung tissue of rat with pulmonary hypertension].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20061101

Title: Mycophenolate mofetil attenuates pulmonary arterial hypertension in rats.

Journal: Biochemical and biophysical research communications 20061020

Title: ROCK controls matrix synthesis in vascular smooth muscle cells: coupling vasoconstriction to vascular remodeling.

Journal: Circulation research 20061013

Title: Myocardial dysfunction and neurohumoral activation without remodeling in left ventricle of monocrotaline-induced pulmonary hypertensive rats.

Journal: American journal of physiology. Heart and circulatory physiology 20061001

Title: Major components in the hairpencil secretion of a butterfly, Euploea mulciber (Lepidoptera, Danaidae): their origins and male behavioral responses to pyrrolizidine alkaloids.

Journal: Journal of insect physiology 20061001

Title: Sequence of echocardiographic changes during development of right ventricular failure in rat.

Journal: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 20061001

Title: Reduced inotropic effect of nifekalant in failing hearts in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20060901

Title: The HMG-CoA reductase inhibitor, pravastatin, prevents the development of monocrotaline-induced pulmonary hypertension in the rat through reduction of endothelial cell apoptosis and overexpression of eNOS.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20060901

Title: How valid are animal models to evaluate treatments for pulmonary hypertension?

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20060901

Title: Upregulated neurohumoral factors are associated with left ventricular remodeling and poor prognosis in rats with monocrotaline-induced pulmonary arterial hypertension.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20060901

Title: Short-term administration of a cell-permeable caveolin-1 peptide prevents the development of monocrotaline-induced pulmonary hypertension and right ventricular hypertrophy.

Journal: Circulation 20060829

Title: Anticoagulation and inhibition of nitric oxide synthase influence hepatic hypoxia after monocrotaline exposure.

Journal: Toxicology 20060815

Title: Microvascular regeneration in established pulmonary hypertension by angiogenic gene transfer.

Journal: American journal of respiratory cell and molecular biology 20060801

Title: Implantation of mesenchymal stem cells overexpressing endothelial nitric oxide synthase improves right ventricular impairments caused by pulmonary hypertension.

Journal: Circulation 20060704

Title: Inotropic and lusitropic effects of ghrelin and their modulation by the endocardial endothelium, NO, prostaglandins, GHS-R1a and KCa channels.

Journal: Peptides 20060701

Title: Role of chymase-dependent angiotensin II formation in monocrotaline-induced pulmonary hypertensive rats.

Journal: Pediatric research 20060701

Title: Myocyte morphological characteristics differ between the phases of pulmonary hypertension-induced ventricular hypertrophy and failure.

Journal: International heart journal 20060701

Title: Remodeling excitation-contraction coupling of hypertrophied ventricular myocytes is dependent on T-type calcium channels expression.

Journal: Biochemical and biophysical research communications 20060630

Title: Discordant regulatory changes in monocrotaline-induced megalocytosis of lung arterial endothelial and alveolar epithelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20060601

Title: Bosentan, sildenafil, and their combination in the monocrotaline model of pulmonary hypertension in rats.

Journal: Experimental biology and medicine (Maywood, N.J.) 20060601

Title: Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension.

Journal: Circulation research 20060526

Title: Upregulation of profilin, cofilin-2 and LIMK2 in cultured pulmonary artery smooth muscle cells and in pulmonary arteries of monocrotaline-treated rats.

Journal: Vascular pharmacology 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Monocrotaline pyrrole-induced megalocytosis of lung and breast epithelial cells: Disruption of plasma membrane and Golgi dynamics and an enhanced unfolded protein response.

Journal: Toxicology and applied pharmacology 20060315

Title: [The change of mast cells and macrophages in the lung of rat with pulmonary hypertension].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060301

Title: Selective right, but not left, coronary endothelial dysfunction precedes development of pulmonary hypertension and right heart hypertrophy in rats.

Journal: American journal of physiology. Heart and circulatory physiology 20060201

Title: Activation of soluble guanylate cyclase reverses experimental pulmonary hypertension and vascular remodeling.

Journal: Circulation 20060117

Title: Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, lasiocarpine.

Journal: Cancer letters 20060108

Title: Heme oxygenase-1 mediates the protective effects of rapamycin in monocrotaline-induced pulmonary hypertension.

Journal: Laboratory investigation; a journal of technical methods and pathology 20060101

Title: Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cells.

Journal: Respiratory research 20060101

Title: Genistein, a phytoestrogen, attenuates monocrotaline-induced pulmonary hypertension.

Journal: Respiration; international review of thoracic diseases 20060101

Title: Ghrelin reverses molecular, structural and hemodynamic alterations of the right ventricle in pulmonary hypertension.

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20060101

Title: Analysis of gene expression changes in relation to toxicity and tumorigenesis in the livers of Big Blue transgenic rats fed comfrey (Symphytum officinale).

Journal: BMC bioinformatics 20060101

Title: Hypoxia and dehydroepiandrosterone in old age: a mouse survival study.

Journal: Respiratory research 20060101

Title: Cardiac hypertrophy induced by prostaglandin F(2alpha) may be mediated by calcineurin signal transduction pathway in rats.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20051225

Title: A long-acting prostacyclin agonist with thromboxane inhibitory activity for pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine 20051215

Title: Doppler tissue imaging in assessment of pulmonary hypertension-induced right ventricle dysfunction.

Journal: American journal of physiology. Heart and circulatory physiology 20051201

Title: Monocrotaline pyrrole targets proteins with and without cysteine residues in the cytosol and membranes of human pulmonary artery endothelial cells.

Journal: Proteomics 20051101

Title: CPU 86017, p-chlorobenzyltetrahydroberberine chloride, attenuates monocrotaline-induced pulmonary hypertension by suppressing endothelin pathway.

Journal: Acta pharmacologica Sinica 20051101

Title: Estradiol metabolites attenuate monocrotaline-induced pulmonary hypertension in rats.

Journal: Journal of cardiovascular pharmacology 20051001

Title: Effects of nicorandil on monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: Journal of cardiovascular pharmacology 20051001

Title: Contractile effects of Ghrelin and expression of its receptor GHS-R1a in normal and hypertrophic myocardium.

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20051001

Title: Excess l-arginine restores endothelium-dependent relaxation impaired by monocrotaline pyrrole.

Journal: Toxicology and applied pharmacology 20050915

Title: Mechanical stress-dependent transcriptional regulation of sarcolipin gene in the rodent atrium.

Journal: Biochemical and biophysical research communications 20050902

Title: The role of increased pulmonary blood flow in pulmonary arterial hypertension.

Journal: The European respiratory journal 20050901

Title: Metabolic activation of the tumorigenic pyrrolizidine alkaloid, monocrotaline, leading to DNA adduct formation in vivo.

Journal: Cancer letters 20050808

Title: Inhaled iloprost reverses vascular remodeling in chronic experimental pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine 20050801

Title: [The effect of compound macrostem onion capsule on metabolism of arachidonic acid in a rat model of monocrotaline-induced pulmonary artery hypertension].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20050801

Title: Epidermal growth factor receptor blockade mediates smooth muscle cell apoptosis and improves survival in rats with pulmonary hypertension.

Journal: Circulation 20050719

Title: Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050701

Title: Immunohistochemical determination of cytosolic cytochrome C concentration in cardiomyocytes.

Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20050701

Title: Development of occlusive neointimal lesions in distal pulmonary arteries of endothelin B receptor-deficient rats: a new model of severe pulmonary arterial hypertension.

Journal: Circulation 20050607

Title: Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats.

Journal: Circulation 20050531

Title: Microarray analysis reveals pivotal divergent mRNA expression profiles early in the development of either compensated ventricular hypertrophy or heart failure.

Journal: Physiological genomics 20050511

Title: ClC-3 chloride channel is upregulated by hypertrophy and inflammation in rat and canine pulmonary artery.

Journal: British journal of pharmacology 20050501

Title: Skeletal muscle myofibrillar protein oxidation in heart failure and the protective effect of Carvedilol.

Journal: Journal of molecular and cellular cardiology 20050501

Title: Macro- and micropulmonary hemodynamic changes to nitric oxide blockade in monocrotaline-induced pulmonary hypertension in rats--an in vivo approach.

Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20050501

Title: [Effects of peroxisome proliferator-activated receptor gamma ligands on monocrotaline-induced pulmonary hypertension in rats].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20050501

Title: Metabolic activation of the tumorigenic pyrrolizidine alkaloid, retrorsine, leading to DNA adduct formation in vivo.

Journal: International journal of environmental research and public health 20050501

Title: Monocrotaline pyrrole-induced endothelial cell megalocytosis involves a Golgi blockade mechanism.

Journal: American journal of physiology. Cell physiology 20050401

Title: Pressure overload and neurohumoral activation differentially affect the myocardial proteome.

Journal: Proteomics 20050401

Title: Decreased vagal control over heart rate in rats with right-sided congestive heart failure: downregulation of neuronal nitric oxide synthase.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20050401

Title: Animal models of heart failure: what is new?

Journal: The Annals of thoracic surgery 20050401

Title: Simvastatin treatment of pulmonary hypertension: an observational case series.

Journal: Chest 20050401

Title: Do naïve ruminants degrade alkaloids in the rumen?

Journal: Journal of chemical ecology 20050401

Title: Differential utilization of pyrrolizidine alkaloids by males of a danaid butterfly, Parantica sita, for the production of danaidone in the alar scent organ.

Journal: Journal of chemical ecology 20050401

Title: Increased pulmonary heme oxygenase-1 and delta-aminolevulinate synthase expression in monocrotaline-induced pulmonary hypertension.

Journal: Current neurovascular research 20050401

Title: Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid.

Journal: Toxicology letters 20050315

Title: Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: efficacy of combined cell and eNOS gene therapy in established disease.

Journal: Circulation research 20050304

Title: Acute intoxication by Crotalaria retusa in sheep.

Journal: Toxicon : official journal of the International Society on Toxinology 20050301

Title: Monocrotaline-induced pulmonary hypertension correlates with upregulation of connective tissue growth factor expression in the lung.

Journal: Experimental & molecular medicine 20050227

Title: Gene transfer of a TIE2 receptor antagonist prevents pulmonary hypertension in rodents.

Journal: The Journal of thoracic and cardiovascular surgery 20050201

Title: [Decrease of nitric oxide (NO)-cGMP-dependent vasodilatation in the vessels of lesser circulation in endothelial dysfunction].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20050201

Title: Monocrotaline, an alternative to retrorsine-based hepatocyte transplantation in rodents.

Journal: Cell transplantation 20050101

Title: PKC translocation and ERK1/2 activation in compensated right ventricular hypertrophy secondary to chronic emphysema.

Journal: BMC physiology 20050101

Title: [Effect of chronic administration of aminoguanidine on vascular reactivity of the greater circulation in rats with monocrotaline-induced pulmonary hypertension].

Journal: Izvestiia Akademii nauk. Seriia biologicheskaia 20050101

Title: Attenuated noradrenaline-induced contraction of pulmonary arteries from rats treated with monocrotaline: role of rho kinase.

Journal: Journal of vascular research 20050101

Title: Influence of hypoxia on the domiciliation of mesenchymal stem cells after infusion into rats: possibilities of targeting pulmonary artery remodeling via cells therapies?

Journal: Respiratory research 20050101

Title: Inhaled tolafentrine reverses pulmonary vascular remodeling via inhibition of smooth muscle cell migration.

Journal: Respiratory research 20050101

Title: If you've got it, flaunt it: ingested alkaloids affect corematal display behavior in the salt marsh moth, Estigmene acrea.

Journal: Journal of insect science (Online) 20050101

Title: Chloride channels and alpha1-adrenoceptor-mediated pulmonary artery smooth muscle contraction: effect of pulmonary hypertension.

Journal: European journal of pharmacology 20041215

Title: DNA cross-linking by dehydromonocrotaline lacks apparent base sequence preference.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20041201

Title: Endogenous production of ghrelin and beneficial effects of its exogenous administration in monocrotaline-induced pulmonary hypertension.

Journal: American journal of physiology. Heart and circulatory physiology 20041201

Title: C-type natriuretic peptide ameliorates monocrotaline-induced pulmonary hypertension in rats.

Journal: American journal of respiratory and critical care medicine 20041201

Title: Gene transfer of hepatocyte growth factor with prostacyclin synthase in severe pulmonary hypertension of rats.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20041201

Title: Specific inhibition of p38 mitogen-activated protein kinase with FR167653 attenuates vascular proliferation in monocrotaline-induced pulmonary hypertension in rats.

Journal: The Journal of thoracic and cardiovascular surgery 20041201

Title: Repeated gene transfer of naked prostacyclin synthase plasmid into skeletal muscles attenuates monocrotaline-induced pulmonary hypertension and prolongs survival in rats.

Journal: Human gene therapy 20041201

Title: Hepatocyte growth factor suppresses vascular medial hyperplasia and matrix accumulation in advanced pulmonary hypertension of rats.

Journal: Circulation 20041102

Title: Comparison of hepatic in vitro metabolism of the pyrrolizidine alkaloid senecionine in sheep and cattle.

Journal: American journal of veterinary research 20041101

Title: YM598, an orally active ET(A) receptor antagonist, ameliorates the progression of cardiopulmonary changes and both-side heart failure in rats with cor pulmonale and myocardial infarction.

Journal: Journal of cardiovascular pharmacology 20041101

Title: Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis.

Journal: Circulation research 20041015

Title: Disruption of endothelial-cell caveolin-1alpha/raft scaffolding during development of monocrotaline-induced pulmonary hypertension.

Journal: Circulation 20040914

Title: The orally active nonpeptide selective endothelin ETA receptor antagonist YM598 prevents and reverses the development of pulmonary hypertension in monocrotaline-treated rats.

Journal: European journal of pharmacology 20040802

Title: Role of endothelin ETB receptor in the pathogenesis of monocrotaline-induced pulmonary hypertension in rats.

Journal: European journal of pharmacology 20040802

Title: Roles of endothelin ETA and ETB receptors in the pathogenesis of monocrotaline-induced pulmonary hypertension.

Journal: Journal of cardiovascular pharmacology 20040801

Title: [Effect of chronic administration of aminoguanidine on the reactivity of pulmonary vessels in rats with monocrotaline-induced pulmonary hypertension].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20040701

Title: Emission-particle-induced ventilatory abnormalities in a rat model of pulmonary hypertension.

Journal: Environmental health perspectives 20040601

Title: Effect of 5-lipoxygenase on the development of pulmonary hypertension in rats.

Journal: American journal of physiology. Heart and circulatory physiology 20040501

Title: [Effect of elastase inhibitor on pulmonary hypertension induced by monocrotaline].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20040501

Title: Antioxidant and oxidative stress changes in experimental cor pulmonale.

Journal: Molecular and cellular biochemistry 20040501

Title: Antiremodeling effects of iloprost and the dual-selective phosphodiesterase 3/4 inhibitor tolafentrine in chronic experimental pulmonary hypertension.

Journal: Circulation research 20040430

Title: Longitudinal transcriptional analysis of developing neointimal vascular occlusion and pulmonary hypertension in rats.

Journal: Physiological genomics 20040413

Title: Cell therapy for pulmonary hypertension: what is the true potential of endothelial progenitor cells?

Journal: Circulation 20040330

Title: Contractile reserve but not tension is reduced in monocrotaline-induced right ventricular hypertrophy.

Journal: American journal of physiology. Heart and circulatory physiology 20040301

Title: Nitric oxide formation and plasma L-arginine levels in pulmonary hypertensive rats.

Journal: Respiratory medicine 20040301

Title: Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats.

Journal: Circulation research 20040220

Title: Right ventricle-sparing heart transplantation effective against iatrogenic pulmonary hypertension.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040201

Title: Downregulation of Kv4.2 and Kv4.3 channel gene expression in right ventricular hypertrophy induced by monocrotaline in rat.

Journal: Acta pharmacologica Sinica 20040201

Title: Acquired and partially de novo synthesized pyrrolizidine alkaloids in two polyphagous arctiids and the alkaloid profiles of their larval food-plants.

Journal: Journal of chemical ecology 20040201

Title: Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats.

Journal: American journal of respiratory and critical care medicine 20040101

Title: Beneficial effects of GH/IGF-1 on skeletal muscle atrophy and function in experimental heart failure.

Journal: American journal of physiology. Cell physiology 20040101

Title: A combination of oral sildenafil and beraprost ameliorates pulmonary hypertension in rats.

Journal: American journal of respiratory and critical care medicine 20040101

Title: Effect of nolomirole on monocrotaline-induced heart failure.

Journal: Pharmacological research 20040101

Title: Modes of cell death in rat liver after monocrotaline exposure.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040101

Title: Effect of endothelin antagonism on contractility, intracellular calcium regulation and calcium regulatory protein expression in right ventricular hypertrophy of the rat.

Journal: Basic & clinical pharmacology & toxicology 20040101

Title: Chronic hypoxia- and monocrotaline-induced elevation of hypoxia-inducible factor-1 alpha levels and pulmonary hypertension.

Journal: Journal of biomedical science 20040101

Title: Comparison of strength properties of normotensive and hypertensive rat pulmonary arteries.

Journal: Biomedical sciences instrumentation 20040101

Title: Transplantation of endothelial progenitor cells into the lung to alleviate pulmonary hypertension in dogs.

Journal: Tissue engineering 20040101

Title: JTV-506, a new K(ATP) channel opener, relaxes pulmonary artery isolated from monocrotaline-treated pulmonary hypertensive rats.

Journal: Journal of anesthesia 20040101

Title: Alpha 1-adrenoceptor subtypes mediating noradrenaline-induced contraction of pulmonary artery from pulmonary hypertensive rats.

Journal: European journal of pharmacology 20031215

Title: Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine alkaloid riddelliine.

Journal: Toxicology letters 20031210

Title: Activation of the right ventricular endothelin (ET) system in the monocrotaline model of pulmonary hypertension: response to chronic ETA receptor blockade.

Journal: Clinical science (London, England : 1979) 20031201

Title: Serotonin receptor antagonist inhibits monocrotaline-induced pulmonary hypertension and prolongs survival in rats.

Journal: Cardiovascular research 20031201

Title: [Involvement of tetrahydrobiopterin in local change of endothelium-dependent vasorelaxation in pulmonary hypertension].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20031201

Title: Basement membrane and matrix metalloproteinases in monocrotaline-induced liver injury.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20031101

Title: Augmented pulmonary vascular and venous constrictions to N(G)-nitro-L-arginine methyl ester in rats with monocrotaline-induced pulmonary hypertension.

Journal: Pharmacology 20031101

Title: Rhythmical contractions in pulmonary arteries of monocrotaline-induced pulmonary hypertensive rats.

Journal: Pflugers Archiv : European journal of physiology 20031101

Title: Experience influences gustatory responsiveness to pyrrolizidine alkaloids in the polyphagous caterpillar, Estigmene acrea.

Journal: Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20031101

Title: Repeated inhalation of adrenomedullin ameliorates pulmonary hypertension and survival in monocrotaline rats.

Journal: American journal of physiology. Heart and circulatory physiology 20031101

Title: Are insect-synthesized retronecine esters (creatonotines) the precursors of the male courtship pheromone in the arctiid moth Estigmene acrea?

Journal: Journal of chemical ecology 20031101

Title: Decreased hepatic nitric oxide production contributes to the development of rat sinusoidal obstruction syndrome.

Journal: Hepatology (Baltimore, Md.) 20031001

Title: Estrogen and enalapril attenuate the development of right ventricular hypertrophy induced by monocrotaline in ovariectomized rats.

Journal: Journal of Korean medical science 20031001

Title: Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells.

Journal: Circulation 20030930

Title: Sinusoidal obstruction syndrome (veno-occlusive disease) in the rat is prevented by matrix metalloproteinase inhibition.

Journal: Gastroenterology 20030901

Title: Identification of DNA adducts derived from riddelliine, a carcinogenic pyrrolizidine alkaloid.

Journal: Chemical research in toxicology 20030901

Title: Liver inflammation during monocrotaline hepatotoxicity.

Journal: Toxicology 20030828

Title: Hybrid cell-gene therapy for pulmonary hypertension based on phagocytosing action of endothelial progenitor cells.

Journal: Circulation 20030819

Title: Mechanical load-dependent regulation of gene expression in monocrotaline-induced right ventricular hypertrophy in the rat.

Journal: Circulation research 20030808

Title: Comparative scoring of micronucleated reticulocytes in rat peripheral blood by flow cytometry and microscopy.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030801

Title: The coagulation system contributes to synergistic liver injury from exposure to monocrotaline and bacterial lipopolysaccharide.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030801

Title: DA-8159, a potent cGMP phosphodiesterase inhibitor, attenuates monocrotaline-induced pulmonary hypertension in rats.

Journal: Archives of pharmacal research 20030801

Title: Endothelial cell injury and coagulation system activation during synergistic hepatotoxicity from monocrotaline and bacterial lipopolysaccharide coexposure.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030701

Title: Taste receptors for pyrrolizidine alkaloids in a monophagous caterpillar.

Journal: Journal of chemical ecology 20030701

Title: Progressive development of pulmonary hypertension leading to right ventricular hypertrophy assessed by echocardiography in rats.

Journal: Experimental animals 20030701

Title: Inhibition of matrix metalloproteinases by lung TIMP-1 gene transfer limits monocrotaline-induced pulmonary vascular remodeling in rats.

Journal: Human gene therapy 20030610

Title: Embolization by sinusoidal lining cells obstructs the microcirculation in rat sinusoidal obstruction syndrome.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030601

Title: Pyrrolizidine alkaloids as oviposition stimulants for the cinnabar moth, Tyria jacobaeae.

Journal: Journal of chemical ecology 20030601

Title: Protective role of angiopoietin-1 in experimental pulmonary hypertension.

Journal: Circulation research 20030516

Title: Granulocyte colony-stimulating factor enhances alpha-naphthylthiourea-induced pulmonary hypertension.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20030501

Title: Effect of a surgical aortocaval fistula on monocrotaline-induced pulmonary hypertension.

Journal: Critical care medicine 20030401

Title: Tachykinin dysfunction attenuates monocrotaline-induced pulmonary hypertension.

Journal: Toxicology and applied pharmacology 20030315

Title: Effects of monocrotaline pyrrole and thrombin on pulmonary endothelial cell junction and matrix adhesion proteins.

Journal: Toxicology 20030303

Title: Role of neutrophils in the synergistic liver injury from monocrotaline and bacterial lipopolysaccharide exposure.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030301

Title: Cardiac beta-adrenoceptor changes in monocrotaline-treated rats: differences between membrane preparations from whole ventricles and isolated ventricular cardiomyocytes.

Journal: Journal of cardiovascular pharmacology 20030301

Title: Skeletal muscle abnormalities in rats with experimentally induced heart hypertrophy and failure.

Journal: Basic research in cardiology 20030301

Title: Final height outcome and value of height prediction in boys with constitutional delay in growth and adolescence treated with intramuscular testosterone 125 mg per month for 3 months.

Journal: Clinical endocrinology 20030301

Title: The role of Kupffer cells and TNF-alpha in monocrotaline and bacterial lipopolysaccharide-induced liver injury.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030101

Title: Cytostatic properties of some angiotensin I converting enzyme inhibitors and of angiotensin II type I receptor antagonists.

Journal: Current pharmaceutical design 20030101

Title: The activation pattern of the antioxidant enzymes in the right ventricle of rat in response to pressure overload is of heart failure type.

Journal: Heart disease (Hagerstown, Md.) 20030101

Title: Gender differences in pulmonary arterial reactivity to dilatory agonists in pulmonary hypertension.

Journal: The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia 20030101

Title: DA-8159, a new PDE5 inhibitor, attenuates the development of compensatory right ventricular hypertrophy in a rat model of pulmonary hypertension.

Journal: The Journal of international medical research 20030101

Title: Dietary alkaloids and the development of androconial organs in Estigmene acrea.

Journal: Journal of insect science (Online) 20030101

Title: Pulmonary effects of ultrafine and fine ammonium salts aerosols in healthy and monocrotaline-treated rats following short-term exposure.

Journal: Inhalation toxicology 20021201

Title: Pyrrolizidine alkaloid clivorine inhibits human normal liver L-02 cells growth and activates p38 mitogen-activated protein kinase in L-02 cells.

Journal: Toxicon : official journal of the International Society on Toxinology 20021201

Title: Ventricular hypertrophy plus neurohumoral activation is necessary to alter the cardiac beta-adrenoceptor system in experimental heart failure.

Journal: Circulation research 20021129

Title: Simvastatin attenuates smooth muscle neointimal proliferation and pulmonary hypertension in rats.

Journal: American journal of respiratory and critical care medicine 20021115

Title: Dexfenfluramine protects against pulmonary hypertension in rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20021101

Title: Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary hypertension in rats.

Journal: American journal of physiology. Heart and circulatory physiology 20021101

Title: Acute and chronic effects of T-1032, a novel selective phosphodiesterase type 5 inhibitor, on monocrotaline-induced pulmonary hypertension in rats.

Journal: Biological & pharmaceutical bulletin 20021101

Title: Cardiac and thermoregulatory effects of instilled particulate matter-associated transition metals in healthy and cardiopulmonary-compromised rats.

Journal: Journal of toxicology and environmental health. Part A 20021025

Title: L-Carnitine: a potential treatment for blocking apoptosis and preventing skeletal muscle myopathy in heart failure.

Journal: American journal of physiology. Cell physiology 20020901

Title: Calibrated histochemistry applied to oxygen supply and demand in hypertrophied rat myocardium.

Journal: Microscopy research and technique 20020901

Title: Pyrrolizidine alkaloids from Senecio jacobaea affect fungal growth.

Journal: Journal of chemical ecology 20020901

Title: Cardiac modulations of ANG II receptor expression in rats with hypoxic pulmonary hypertension.

Journal: American journal of physiology. Heart and circulatory physiology 20020801

Title: Effect of thalidomide on the skeletal muscle in experimental heart failure.

Journal: European journal of heart failure 20020801

Title: Heme oxygenase-1 reduces murine monocrotaline-induced pulmonary inflammatory responses and resultant right ventricular overload.

Journal: Antioxidants & redox signaling 20020801

Title: Reduction of monocrotaline-induced hepatic injury by deleted variant of hepatocyte growth factor (dHGF) in rats.

Journal: Liver 20020801

Title: [The effect and mechanism of felodipine on monocrotaline induced pulmonary hypertension in rats].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20020801

Title: The temporal relationship between bacterial lipopolysaccharide and monocrotaline exposures influences toxicity: shift in response from hepatotoxicity to nitric oxide-dependent lethality.

Journal: Journal of toxicology and environmental health. Part A 20020726

Title: Serial noninvasive assessment of progressive pulmonary hypertension in a rat model.

Journal: American journal of physiology. Heart and circulatory physiology 20020701

Title: Effects of diesel exhaust enriched concentrated PM2.5 in ozone preexposed or monocrotaline-treated rats.

Journal: Inhalation toxicology 20020701

Title: Dietary fish oil protects against lung and liver inflammation and fibrosis in monocrotaline treated rats.

Journal: Toxicology 20020614

Title: Suppressive effect of pulmonary hypertension and leukocyte activation by inhaled prostaglandin E1 in rats with monocrotaline-induced pulmonary hypertension.

Journal: Experimental lung research 20020601

Title: Attenuation of negatively regulated ANP secretion by calcium in hypertrophied atria.

Journal: Regulatory peptides 20020530

Title: Anticoagulants prevent monocrotaline-induced hepatic parenchymal cell injury but not endothelial cell injury in the rat.

Journal: Toxicology and applied pharmacology 20020501

Title: Stage-dependent activation of cell cycle and apoptosis mechanisms in the right ventricle by pressure overload.

Journal: Biochimica et biophysica acta 20020424

Title: The effects of vasoactive intestinal peptide on monocrotaline induced pulmonary hypertensive rabbits following cardiopulmonary bypass: a comparative study with isoproteronol and nitroglycerine.

Journal: Cardiovascular surgery (London, England) 20020401

Title: Temporal modulation of pyrrolizidine alkaloid intake and genetic variation in performance of Utetheisa ornatrix caterpillars.

Journal: Journal of chemical ecology 20020401

Title: Therapeutic effects of DCDDP, a calcium channel blocker, on chronic pulmonary hypertension in rat.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20020301

Title: Defective intracellular calcium handling in monocrotaline-induced right ventricular hypertrophy: protective effect of long-term endothelin-A receptor blockade with 2-benzo[1,3]dioxol-5-yl-3-benzyl-4-(4-methoxy-phenyl-)- 4-oxobut-2-enoate-sodium (PD 155080).

Journal: The Journal of pharmacology and experimental therapeutics 20020201

Title: Endothelial cell injury and fibrin deposition in rat liver after monocrotaline exposure.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020201

Title: Changes in alpha(1)-adrenergic vascular reactivity in monocrotaline-treated rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20020201

Title: Changes of sequestered leukocytes and platelets by inhalation prostaglandin E(1) in the pulmonary microvasculature of rats with monocrotaline-induced pulmonary hypertension.

Journal: Journal of vascular research 20020101

Title: Effects of monocrotaline on endothelial nitric oxide synthase expression and sulfhydryl levels in rat lungs.

Journal: Heart disease (Hagerstown, Md.) 20020101

Title: Myocardial force development and structural changes associated with monocrotaline induced cardiac hypertrophy and heart failure.

Journal: Journal of muscle research and cell motility 20020101

Title: Attenuation of inhibitory effect of CNP on the secretion of ANP from hypertrophied atria.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20011101

Title: Gelatinase expression in pulmonary arteries during experimental pulmonary hypertension.

Journal: The European respiratory journal 20011101

Title: Gemtuzumab Ozogamicin (Mylotarg) and hepatic veno-occlusive disease: take two acetaminophen, and..

Journal: Bone marrow transplantation 20011101

Title: Cell-based gene transfer of vascular endothelial growth factor attenuates monocrotaline-induced pulmonary hypertension.

Journal: Circulation 20011030

Title: Accentuation of ANP secretion to endothelin-1 in hypertrophied atria.

Journal: Regulatory peptides 20011015

Title: Decrease in the Ca2+-activated K+ current of pulmonary arterial smooth muscle in pulmonary hypertension rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010901

Title: Time- and subunit-dependent differential mRNA expression of L-type Ca2+ channel during progression of right ventricular hypertrophy.

Journal: Japanese heart journal 20010901

Title: Angiotensin-converting enzyme inhibitor preserves p21 and endothelial nitric oxide synthase expression in monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: Circulation 20010821

Title: Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles.

Journal: Toxicology and applied pharmacology 20010815

Title: Attenuation of compensatory right ventricular hypertrophy and heart failure following monocrotaline-induced pulmonary vascular injury by the Na+-H+ exchange inhibitor cariporide.

Journal: The Journal of pharmacology and experimental therapeutics 20010801

Title: Restoration of calcium handling properties of adult cardiac myocytes from hypertrophied hearts.

Journal: Cell calcium 20010701

Title: Lack of protective action of cysteine against the fetotoxic effect of monocrotaline.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010701

Title: Contribution of chloride channel activation to the elevated muscular tone of the pulmonary artery in monocrotaline-induced pulmonary hypertensive rats.

Journal: Japanese journal of pharmacology 20010701

Title: [Monocrotaline-induced pulmonary hypertension in animals].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010601

Title: [Drug induced pulmonary hypertension].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010601

Title: Beneficial effects on skeletal muscle of the angiotensin II type 1 receptor blocker irbesartan in experimental heart failure.

Journal: Circulation 20010501

Title: All-trans retinoic acid in pulmonary vascular structural remodeling in rats with pulmonary hypertension induced by monocrotaline.

Journal: Chinese medical journal 20010501

Title: Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity.

Journal: Toxicology letters 20010331

Title: Reactive oxygen species and substance P in monocrotaline-induced pulmonary hypertension.

Journal: Toxicology and applied pharmacology 20010315

Title: Enhanced gene expression of renin-angiotensin system, TGF-beta1, endothelin-1 and nitric oxide synthase in right-ventricular hypertrophy.

Journal: Pharmacological research 20010301

Title: Apoptosis and changes in contractile protein pattern in the skeletal muscle in heart failure.

Journal: Acta physiologica Scandinavica 20010301

Title: 5-HT1B receptor augmented 5-HT vasoconstrictor response of pulmonary artery in monocrotaline-induced pulmonary hypertensive rats.

Journal: Acta pharmacologica Sinica 20010301

Title: Hemodynamic unloading leads to regression of pulmonary vascular disease in rats.

Journal: The Journal of thoracic and cardiovascular surgery 20010201

Title: 40-O-(2-hydroxyethyl)-rapamycin attenuates pulmonary arterial hypertension and neointimal formation in rats.

Journal: American journal of respiratory and critical care medicine 20010201

Title: Effectiveness of a nonselective ET(A/B) and a selective ET(A) antagonist in rats with monocrotaline-induced pulmonary hypertension.

Journal: Circulation 20010116

Title: Development of a (32)P-postlabeling/HPLC method for detection of dehydroretronecine-derived DNA adducts in vivo and in vitro.

Journal: Chemical research in toxicology 20010101

Title: Metabolic activation of the tumorigenic pyrrolizidine alkaloid, riddelliine, leading to DNA adduct formation in vivo.

Journal: Chemical research in toxicology 20010101

Title: Vascular remodeling in experimentally induced subacute canine pulmonary hypertension.

Journal: Experimental lung research 20010101

Title: Micronucleus formation in human lymphocytes and in the metabolically competent human hepatoma cell line Hep-G2: results with 15 naturally occurring substances.

Journal: Anticancer research 20010101

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Journal: Pneumologia (Bucharest, Romania) 20010101

Title: Role of endothelin-1 in lung disease.

Journal: Respiratory research 20010101

Title: Genomic approaches to research in pulmonary hypertension.

Journal: Respiratory research 20010101

Title: Molecular mechanisms of cardiac hypertrophy induced by toxicants.

Journal: Cardiovascular toxicology 20010101

Title: Polyamine regulatory processes and oxidative stress in monocrotaline-treated pulmonary artery endothelial cells.

Journal: Cell biology international 19971201

Title: Oxidative stress mediates monocrotaline-induced alterations in tenascin expression in pulmonary artery endothelial cells.

Journal: The international journal of biochemistry & cell biology 19970501

Title: Effect of losartan on right ventricular hypertrophy and cardiac angiotensin I-converting enzyme activity in pulmonary hypertensive rats.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 19960101

Title: Pinacidil-induced relaxation in pulmonary arteries isolated from pulmonary hypertensive and normotensive rats and pre-contracted with different spasmogens.

Journal: Pulmonary pharmacology 19941201

Title: COR pulmonale is caused by monocrotaline and dehydromonocrotaline, but not by glutathione or cysteine conjugates of dihydropyrrolizine.

Journal: Toxicology and applied pharmacology 19930101

Title: Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.

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Tags:315-22-0 Molecular Formula|315-22-0 MDL|315-22-0 SMILES|315-22-0 Monocrotaline
Catalog No.: AA00BY83
315-22-0,MFCD00084656
315-22-0 | Monocrotaline
Pack Size: 50mg
Purity: ≥98%
in stock
$89.00 $62.00
Pack Size: 100mg
Purity: ≥98%
in stock
$165.00 $115.00
Pack Size: 250mg
Purity: 98%
in stock
$214.00 $150.00
Pack Size: 500mg
Purity: ≥98%
in stock
$342.00 $239.00
Pack Size: 1g
Purity: 98%
in stock
$460.00 $322.00
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Technical Information
Catalog Number: AA00BY83
Chemical Name: Monocrotaline
CAS Number: 315-22-0
Molecular Formula: C16H23NO6
Molecular Weight: 325.3569
MDL Number: MFCD00084656
SMILES: O=C1O[C@@H]2CCN3[C@@H]2C(=CC3)COC(=O)[C@]([C@]([C@H]1C)(C)O)(C)O
Properties
Form: Solid  
MP: >140°C (dec.)  
Storage: Keep in dry area;2-8℃;  
Complexity: 575  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 5  
Heavy Atom Count: 23  
Hydrogen Bond Acceptor Count: 7  
Hydrogen Bond Donor Count: 2  
XLogP3: -0.7  
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Title: Integrative analysis of hepatic microRNA and mRNA to identify potential biological pathways associated with monocrotaline-induced liver injury in mice.

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Title: Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action.

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Title: The flavonoid quercetin reverses pulmonary hypertension in rats.

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Title: Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important role in its hepatotoxicity.

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Title: Tissue factor antisense deoxyoligonucleotide prevents monocrotaline/LPS hepatotoxicity in mice.

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Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

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Title: Sorafenib attenuates monocrotaline-induced sinusoidal obstruction syndrome in rats through suppression of JNK and MMP-9.

Journal: Journal of hepatology20121101

Title: Bortezomib alleviates experimental pulmonary arterial hypertension.

Journal: American journal of respiratory cell and molecular biology20121101

Title: Superiority of desflurane over sevoflurane and isoflurane in the presence of pressure-overload right ventricle hypertrophy in rats.

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Title: Immune and inflammatory cell involvement in the pathology of idiopathic pulmonary arterial hypertension.

Journal: American journal of respiratory and critical care medicine20121101

Title: Beneficial effects of γ-aminobutyric acid on right ventricular pressure and pulmonary vascular remodeling in experimental pulmonary hypertension.

Journal: Life sciences20121015

Title: Comparison of metabolism-mediated effects of pyrrolizidine alkaloids in a HepG2/C3A cell-S9 co-incubation system and quantification of their glutathione conjugates.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20121001

Title: A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents.

Journal: American journal of respiratory and critical care medicine20121001

Title: Dysregulated renin-angiotensin-aldosterone system contributes to pulmonary arterial hypertension.

Journal: American journal of respiratory and critical care medicine20121001

Title: Benzenesulfonamide attenuates monocrotaline-induced pulmonary arterial hypertension in a rat model.

Journal: European journal of pharmacology20120905

Title: Cardiac and vascular atrogin-1 mRNA expression is not associated with dexamethasone efficacy in the monocrotaline model of pulmonary hypertension.

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Title: Plumbagin reverses proliferation and resistance to apoptosis in experimental PAH.

Journal: The European respiratory journal20120901

Title: Atorvastatin prevents dehydromonocrotaline-induced pulmonary hypertension in beagles.

Journal: Experimental lung research20120901

Title: Impaired natural killer cell phenotype and function in idiopathic and heritable pulmonary arterial hypertension.

Journal: Circulation20120828

Title: Enhanced Ca(2+)-sensing receptor function in idiopathic pulmonary arterial hypertension.

Journal: Circulation research20120803

Title: Attenuation of monocrotaline-induced pulmonary arterial hypertension in rats by rosuvastatin.

Journal: Journal of cardiovascular pharmacology20120801

Title: Genistein, a soy phytoestrogen, reverses severe pulmonary hypertension and prevents right heart failure in rats.

Journal: Hypertension (Dallas, Tex. : 1979)20120801

Title: Caveolin-1 expression during the progression of pulmonary hypertension.

Journal: Experimental biology and medicine (Maywood, N.J.)20120801

Title: The flavonoid monoHER prevents monocrotaline-induced hepatic sinusoidal injury in rats.

Journal: Journal of surgical oncology20120701

Title: Effects of purple grape juice in the redox-sensitive modulation of right ventricular remodeling in a pulmonary arterial hypertension model.

Journal: Journal of cardiovascular pharmacology20120701

Title: The Rho kinase inhibitor azaindole-1 has long-acting vasodilator activity in the pulmonary vascular bed of the intact chest rat.

Journal: Canadian journal of physiology and pharmacology20120701

Title: Reverse right ventricular structural and extracellular matrix remodeling by estrogen in severe pulmonary hypertension.

Journal: Journal of applied physiology (Bethesda, Md. : 1985)20120701

Title: Effect of chronic sodium nitrite therapy on monocrotaline-induced pulmonary hypertension.

Journal: Nitric oxide : biology and chemistry20120630

Title: Haemodynamic and neuroendocrine effects of tezosentan in chronic experimental pulmonary hypertension.

Journal: Intensive care medicine20120601

Title: Cardiac arrhythmia mechanisms in rats with heart failure induced by pulmonary hypertension.

Journal: American journal of physiology. Heart and circulatory physiology20120601

Title: Role of Src tyrosine kinases in experimental pulmonary hypertension.

Journal: Arteriosclerosis, thrombosis, and vascular biology20120601

Title: Changes of gene expression after bone marrow cell transfusion in rats with monocrotaline-induced pulmonary hypertension.

Journal: Journal of Korean medical science20120601

Title: [Pathological changes of monocrotaline-induced pulmonary hypertension in miniature pigs].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University20120601

Title: Combined effects of the ATP-sensitive potassium channel opener pinacidil and simvastatin on pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.

Journal: Die Pharmazie20120601

Title: Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.

Journal: Circulation research20120525

Title: Mechanical load-dependent cardiac ER stress in vitro and in vivo: effects of preload and afterload.

Journal: FEBS letters20120507

Title: Implantation of mesenchymal stem cells improves right ventricular impairments caused by experimental pulmonary hypertension.

Journal: The American journal of the medical sciences20120501

Title: Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology20120501

Title: [Pathophysiological characteristics of rat pulmonary hypertension and cor pulmonale induced by monocrotaline].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology20120501

Title: Oxygen radicals and substance P in perinatal hypoxia-exaggerated, monocrotaline-induced pulmonary hypertension.

Journal: The Chinese journal of physiology20120430

Title: Effects of 2-azafluorenones on phosphatidyl-inositol specific phospholipase C activation in c6 glioma cells.

Journal: The Chinese journal of physiology20120430

Title: PAR-2 inhibition reverses experimental pulmonary hypertension.

Journal: Circulation research20120427

Title: Cardiac-specific genetic inhibition of nuclear factor-κB prevents right ventricular hypertrophy induced by monocrotaline.

Journal: American journal of physiology. Heart and circulatory physiology20120415

Title: Dehydropyrrolizidine alkaloids, including monoesters with an unusual esterifying acid, from cultivated Crotalaria juncea (Sunn Hemp cv.'Tropic Sun').

Journal: Journal of agricultural and food chemistry20120411

Title: Fluoxetine protects against monocrotaline-induced pulmonary arterial remodeling by inhibition of hypoxia-inducible factor-1α and vascular endothelial growth factor.

Journal: Canadian journal of physiology and pharmacology20120401

Title: Angiotensin-converting enzyme 2 activation protects against pulmonary arterial hypertension through improving early endothelial function and mediating cytokines levels.

Journal: Chinese medical journal20120401

Title: Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1.

Journal: Cardiovascular research20120315

Title: Lung ¹⁸F-fluorodeoxyglucose positron emission tomography for diagnosis and monitoring of pulmonary arterial hypertension.

Journal: American journal of respiratory and critical care medicine20120315

Title: Effects of everolimus in combination with sildenafil in monocrotaline-induced pulmonary hypertension in rats.

Journal: Cardiovascular toxicology20120301

Title: Mast cell inhibition improves pulmonary vascular remodeling in pulmonary hypertension.

Journal: Chest20120301

Title: Attenuation of the extract from Moringa oleifera on monocrotaline-induced pulmonary hypertension in rats.

Journal: The Chinese journal of physiology20120227

Title: The monocrotaline model of pulmonary hypertension in perspective.

Journal: American journal of physiology. Lung cellular and molecular physiology20120215

Title: Targeted gene delivery of BMPR2 attenuates pulmonary hypertension.

Journal: The European respiratory journal20120201

Title: Spontaneous ventricular fibrillation in right ventricular failure secondary to chronic pulmonary hypertension.

Journal: Circulation. Arrhythmia and electrophysiology20120201

Title: Sildenafil prevents and reverses transverse-tubule remodeling and Ca(2+) handling dysfunction in right ventricle failure induced by pulmonary artery hypertension.

Journal: Hypertension (Dallas, Tex. : 1979)20120201

Title: Year in review in Intensive Care Medicine 2011: I. Nephrology, epidemiology, nutrition and therapeutics, neurology, ethical and legal issues, experimentals.

Journal: Intensive care medicine20120201

Title: [Genistein attenuates monocrotaline-induced pulmonary arterial hypertension in rats by up-regulating heme oxygenase-1 expression].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University20120201

Title: Factor VIII can be synthesized in hemophilia A mice liver by bone marrow progenitor cell-derived hepatocytes and sinusoidal endothelial cells.

Journal: Stem cells and development20120101

Title: Transgenic expression of human matrix metalloproteinase-1 attenuates pulmonary arterial hypertension in mice.

Journal: Clinical science (London, England : 1979)20120101

Title: Fibrosis of pulmonary vascular remodeling in carotid artery-jugular vein shunt pulmonary artery hypertension model of rats.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery20120101

Title: Enhanced store-operated Ca²+ entry and TRPC channel expression in pulmonary arteries of monocrotaline-induced pulmonary hypertensive rats.

Journal: American journal of physiology. Cell physiology20120101

Title: Development and characterization of an animal model of severe pulmonary arterial hypertension.

Journal: Journal of vascular research20120101

Title: Regional skeletal muscle remodeling and mitochondrial dysfunction in right ventricular heart failure.

Journal: American journal of physiology. Heart and circulatory physiology20120101

Title: Resveratrol reverses monocrotaline-induced pulmonary vascular and cardiac dysfunction: a potential role for atrogin-1 in smooth muscle.

Journal: Vascular pharmacology20120101

Title: Bisoprolol delays progression towards right heart failure in experimental pulmonary hypertension.

Journal: Circulation. Heart failure20120101

Title: TGFβ signaling and cardiovascular diseases.

Journal: International journal of biological sciences20120101

Title: Effects of autologous bone marrow mononuclear cells implantation in canine model of pulmonary hypertension.

Journal: Circulation journal : official journal of the Japanese Circulation Society20120101

Title: New cardiovascular and pulmonary therapeutic strategies based on the Angiotensin-converting enzyme 2/angiotensin-(1-7)/mas receptor axis.

Journal: International journal of hypertension20120101

Title: Independent recruitment of a flavin-dependent monooxygenase for safe accumulation of sequestered pyrrolizidine alkaloids in grasshoppers and moths.

Journal: PloS one20120101

Title: Chronic allergic inflammation causes vascular remodeling and pulmonary hypertension in BMPR2 hypomorph and wild-type mice.

Journal: PloS one20120101

Title: Comparative potential therapeutic effect of sesame oil and peanut oil against acute monocrotaline (Crotalaria) poisoning in a rat model.

Journal: Journal of veterinary internal medicine20120101

Title: Relation of bosentan, iloprost, and sildenafil with growth factor levels in monocrotaline-induced pulmonary hypertension.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993)20120101

Title: Liver disorders in inflammatory bowel disease.

Journal: Gastroenterology research and practice20120101

Title: Nicorandil attenuates monocrotaline-induced vascular endothelial damage and pulmonary arterial hypertension.

Journal: PloS one20120101

Title: Early treatment with fumagillin, an inhibitor of methionine aminopeptidase-2, prevents Pulmonary Hypertension in monocrotaline-injured rats.

Journal: PloS one20120101

Title: Targeting the adventitial microenvironment in pulmonary hypertension: A potential approach to therapy that considers epigenetic change.

Journal: Pulmonary circulation20120101

Title: Serum osteoprotegerin is increased and predicts survival in idiopathic pulmonary arterial hypertension.

Journal: Pulmonary circulation20120101

Title: Identification of functional progenitor cells in the pulmonary vasculature.

Journal: Pulmonary circulation20120101

Title: Smooth muscle myosin inhibition: a novel therapeutic approach for pulmonary hypertension.

Journal: PloS one20120101

Title: Acute effects of vardenafil on pulmonary artery responsiveness in pulmonary hypertension.

Journal: TheScientificWorldJournal20120101

Title: Longitudinal in vivo SPECT/CT imaging reveals morphological changes and cardiopulmonary apoptosis in a rodent model of pulmonary arterial hypertension.

Journal: PloS one20120101

Title: Activation of the unfolded protein response is associated with pulmonary hypertension.

Journal: Pulmonary circulation20120101

Title: The Role of Astrocytes in Metabolism and Neurotoxicity of the Pyrrolizidine Alkaloid Monocrotaline, the Main Toxin of Crotalaria retusa.

Journal: Frontiers in pharmacology20120101

Title: Comparison of two experimental models of pulmonary hypertension.

Journal: Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia20120101

Title: Nicorandil prevents right ventricular remodeling by inhibiting apoptosis and lowering pressure overload in rats with pulmonary arterial hypertension.

Journal: PloS one20120101

Title: Assessment of neurotoxicity of monocrotaline, an alkaloid extracted from Crotalaria retusa in astrocyte/neuron co-culture system.

Journal: Neurotoxicology20111201

Title: Association of the time course of pulmonary arterial hypertension with changes in oxidative stress in the left ventricle.

Journal: Clinical and experimental pharmacology & physiology20111201

Title: Morphological aspects of neuromuscular junctions and gene expression of nicotinic acetylcholine receptors (nAChRs) in skeletal muscle of rats with heart failure.

Journal: Journal of molecular histology20111201

Title: C-122, a novel antagonist of serotonin receptor 5-HT2B, prevents monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: European journal of pharmacology20111116

Title: Therapeutic sesamol attenuates monocrotaline-induced sinusoidal obstruction syndrome in rats by inhibiting matrix metalloproteinase-9.

Journal: Cell biochemistry and biophysics20111101

Title: ¹H NMR study of monocrotaline and its metabolites in human blood.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20111101

Title: Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension.

Journal: American journal of physiology. Heart and circulatory physiology20111101

Title: Egr-1 expression during neointimal development in flow-associated pulmonary hypertension.

Journal: The American journal of pathology20111101

Title: Evidence of diminished coronary flow in pulmonary hypertension: explaining angina pectoris in this patient group?

Journal: Clinical physiology and functional imaging20111101

Title: Stem-cell therapy in an experimental model of pulmonary hypertension and right heart failure: role of paracrine and neurohormonal milieu in the remodeling process.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation20111101

Title: Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease.

Journal: The Journal of clinical investigation20111101

Title: Silencing of tissue factor by antisense deoxyoligonucleotide prevents monocrotaline/LPS renal injury in mice.

Journal: Archives of toxicology20111001

Title: Matrix metalloproteinase-2 (MMP-2) and membrane-type 1 MMP (MT1-MMP) affect the remodeling of glomerulosclerosis in diabetic OLETF rats.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20111001

Title: A role for coagulation factor Xa in experimental pulmonary arterial hypertension.

Journal: Cardiovascular research20111001

Title: Advances in tenascin-C biology.

Journal: Cellular and molecular life sciences : CMLS20111001

Title: Alteration of pulmonary artery integrin levels in chronic hypoxia and monocrotaline-induced pulmonary hypertension.

Journal: Journal of vascular research20111001

Title: Simvastatin protects against the development of monocrotaline-induced pulmonary hypertension in rats via a heme oxygenase-1-dependent pathway.

Journal: Experimental lung research20111001

Title: The relationship between structurally different pyrrolizidine alkaloids and western flower thrips resistance in F(2) hybrids of Jacobaea vulgaris and Jacobaea aquatica.

Journal: Journal of chemical ecology20111001

Title: Influence of estrogen on pulmonary arterial hypertension: role of oxidative stress.

Journal: Cell biochemistry and function20111001

Title: [Determination of pulmonary vascular resistance by improved right heart catheter in rat].

Journal: Zhonghua xin xue guan bing za zhi20111001

Title: Efficacy of aminaftone in a rat model of monocrotaline-induced pulmonary hypertension.

Journal: European journal of pharmacology20110930

Title: Estrogen rescues preexisting severe pulmonary hypertension in rats.

Journal: American journal of respiratory and critical care medicine20110915

Title: Oxidized low-density lipoprotein and tissue factor are involved in monocrotaline/lipopolysaccharide-induced hepatotoxicity.

Journal: Archives of toxicology20110901

Title: Aspirin attenuates pulmonary arterial hypertension in rats by reducing plasma 5-hydroxytryptamine levels.

Journal: Cell biochemistry and biophysics20110901

Title: Rosuvastatin attenuates monocrotaline-induced pulmonary hypertension via regulation of Akt/eNOS signaling and asymmetric dimethylarginine metabolism.

Journal: European journal of pharmacology20110901

Title: Intralipid prevents and rescues fatal pulmonary arterial hypertension and right ventricular failure in rats.

Journal: Hypertension (Dallas, Tex. : 1979)20110901

Title: Changes of pulmonary pathology and gene expressions after simvastatin treatment in the monocrotaline-induced pulmonary hypertension rat model.

Journal: Korean circulation journal20110901

Title: Urantide alleviates monocrotaline induced pulmonary arterial hypertension in Wistar rats.

Journal: Pulmonary pharmacology & therapeutics20110801

Title: Rapid quantification of myocardial fibrosis: a new macro-based automated analysis.

Journal: Cellular oncology (Dordrecht)20110801

Title: Levosimendan attenuates pulmonary vascular remodeling.

Journal: Intensive care medicine20110801

Title: Exacerbated pulmonary arterial hypertension and right ventricular hypertrophy in animals with loss of function of extracellular superoxide dismutase.

Journal: Hypertension (Dallas, Tex. : 1979)20110801

Title: Rodent models of pulmonary hypertension: harmonisation with the world health organisation's categorisation of human PH.

Journal: International journal of clinical practice. Supplement20110801

Title: Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension.

Journal: Journal of molecular medicine (Berlin, Germany)20110801

Title: [Transplantation of marrow mesenchymal stem cells transfected with vascular endothelial growth factor gene for the treatment of pulmonary hypertension in rats].

Journal: Zhonghua yi xue za zhi20110712

Title: Perivascular T-cell infiltration leads to sustained pulmonary artery remodeling after endothelial cell damage.

Journal: American journal of respiratory cell and molecular biology20110701

Title: Treatment of pulmonary arterial hypertension with circulating angiogenic cells.

Journal: American journal of physiology. Lung cellular and molecular physiology20110701

Title: Tissue factor dependent liver injury causes release of retinoid receptors (RXR-α and RAR-α) as lipid droplets.

Journal: Biochemical and biophysical research communications20110624

Title: Mast cells promote lung vascular remodelling in pulmonary hypertension.

Journal: The European respiratory journal20110601

Title: Arrhythmogenic substrate in hearts of rats with monocrotaline-induced pulmonary hypertension and right ventricular hypertrophy.

Journal: American journal of physiology. Heart and circulatory physiology20110601

Title: Downregulation of osteopontin is associated with fluoxetine amelioration of monocrotaline-induced pulmonary inflammation and vascular remodelling.

Journal: Clinical and experimental pharmacology & physiology20110601

Title: Dexamethasone attenuates development of monocrotaline-induced pulmonary arterial hypertension.

Journal: Molecular biology reports20110601

Title: Differential morphofunctional characteristics and gene expression in fast and slow muscle of rats with monocrotaline-induced heart failure.

Journal: Journal of molecular histology20110601

Title: Cytotoxicity of monocrotaline in isolated rat hepatocytes: effects of dithiothreitol and fructose.

Journal: Toxicon : official journal of the International Society on Toxinology20110601

Title: Peptide-directed highly selective targeting of pulmonary arterial hypertension.

Journal: The American journal of pathology20110601

Title: Diaphragm muscle fiber weakness in pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine20110515

Title: Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats.

Journal: The European respiratory journal20110501

Title: New perspectives for the treatment of pulmonary hypertension.

Journal: British journal of pharmacology20110501

Title: Involvement of BMPR2 in the protective effect of fluoxetine against monocrotaline-induced endothelial apoptosis in rats.

Journal: Canadian journal of physiology and pharmacology20110501

Title: [Studies on the alkaloids of Senecio scandens growing in Guangdong].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20110501

Title: Impact of pulmonary vascular resistances in heart transplantation for congenital heart disease.

Journal: Current cardiology reviews20110501

Title: Dexamethasone reverses monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: The European respiratory journal20110401

Title: Suppression of tissue inhibitors of metalloproteinases may reverse severe pulmonary arterial hypertension.

Journal: Cytotherapy20110401

Title: Role of Rho-kinase signaling and endothelial dysfunction in modulating blood flow distribution in pulmonary hypertension.

Journal: Journal of applied physiology (Bethesda, Md. : 1985)20110401

Title: Hepatocyte growth factor improves the survival of rats with pulmonary arterial hypertension via the amelioration of pulmonary hemodynamics.

Journal: International journal of molecular medicine20110401

Title: Doppler flow spectra of the superior vena cava in a rat model of chronic pulmonary hypertension.

Journal: Laboratory animals20110401

Title: Effects of simvastatin on pulmonary C-fiber sensitivity in rats with monocrotaline-induced pulmonary hypertension.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation20110301

Title: Pulmonary and systemic vasodilator responses to the soluble guanylyl cyclase activator, BAY 60-2770, are not dependent on endogenous nitric oxide or reduced heme.

Journal: American journal of physiology. Heart and circulatory physiology20110301

Title: [Effects of rosuvastatin on monocrotaline-induced pulmonary artery hypertension in rats].

Journal: Zhonghua xin xue guan bing za zhi20110301

Title: [Evaluation of vitro hepatotoxicity of monocrotaline by precision-cut liver slice technique].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20110301

Title: [Simultaneous quantitation of adonifoline and senecionine in Senecio herbs by UPLC-MS].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20110301

Title: Right ventricular failure following chronic pressure overload is associated with reduction in left ventricular mass: evidence for atrophic remodeling.

Journal: Journal of the American College of Cardiology20110222

Title: Transgenic expression of human matrix metalloproteinase-9 augments monocrotaline-induced pulmonary arterial hypertension in mice.

Journal: Journal of hypertension20110201

Title: Fluoxetine inhibited extracellular matrix of pulmonary artery and inflammation of lungs in monocrotaline-treated rats.

Journal: Acta pharmacologica Sinica20110201

Title: Nanoparticle-mediated delivery of pitavastatin into lungs ameliorates the development and induces regression of monocrotaline-induced pulmonary artery hypertension.

Journal: Hypertension (Dallas, Tex. : 1979)20110201

Title: Emerging pathogenetic mechanisms of pulmonary arterial hypertension: nitric oxide and more.

Journal: Korean circulation journal20110201

Title: Gene expressions of nitric oxide synthase and matrix metalloproteinase-2 in monocrotaline-induced pulmonary hypertension in rats after bosentan treatment.

Journal: Korean circulation journal20110201

Title: [Toxicity of monocrotaline on in vitro cultured mouse embryos].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20110201

Title: The effects of antiangiogenic compound SU5416 in a rat model of pulmonary arterial hypertension.

Journal: Respiration; international review of thoracic diseases20110101

Title: Perturbations in ataxia telangiectasia mutant signaling pathways after drug-induced acute liver failure and their reversal during rescue of animals by cell therapy.

Journal: The American journal of pathology20110101

Title: Pressure load: the main factor for altered gene expression in right ventricular hypertrophy in chronic hypoxic rats.

Journal: PloS one20110101

Title: Placenta growth factor and vascular endothelial growth factor B expression in the hypoxic lung.

Journal: Respiratory research20110101

Title: The protective effects of cerium oxide nanoparticles against hepatic oxidative damage induced by monocrotaline.

Journal: International journal of nanomedicine20110101

Title: Protective effects of hydrogen-rich saline on monocrotaline-induced pulmonary hypertension in a rat model.

Journal: Respiratory research20110101

Title: Ang-(1-7) might prevent the development of monocrotaline induced pulmonary arterial hypertension in rats.

Journal: European review for medical and pharmacological sciences20110101

Title: Role of the gap junctions in the contractile response to agonists in pulmonary artery from two rat models of pulmonary hypertension.

Journal: Respiratory research20110101

Title: Acceleration of Ca2+ waves in monocrotaline-induced right ventricular hypertrophy in the rat.

Journal: Circulation journal : official journal of the Japanese Circulation Society20110101

Title: [A sharp increase in the density of pulmonary and pericardial mast cells under monocrotaline-induced pulmonary hypertension in rats].

Journal: Tsitologiia20110101

Title: Prospect of vasoactive intestinal peptide therapy for COPD/PAH and asthma: a review.

Journal: Respiratory research20110101

Title: Phosphodiesterase 10A upregulation contributes to pulmonary vascular remodeling.

Journal: PloS one20110101

Title: Pulmonary arterial dysfunction in insulin resistant obese Zucker rats.

Journal: Respiratory research20110101

Title: Glycogen synthase kinase 3beta contributes to proliferation of arterial smooth muscle cells in pulmonary hypertension.

Journal: PloS one20110101

Title: MicroRNA let-7f inhibits tumor invasion and metastasis by targeting MYH9 in human gastric cancer.

Journal: PloS one20110101

Title: Involvement of mast cells in monocrotaline-induced pulmonary hypertension in rats.

Journal: Respiratory research20110101

Title: Recent trends in pulmonary arterial hypertension.

Journal: Lung India : official organ of Indian Chest Society20110101

Title: Cell-specific dual role of caveolin-1 in pulmonary hypertension.

Journal: Pulmonary medicine20110101

Title: Therapeutic strategies in pulmonary hypertension.

Journal: Frontiers in pharmacology20110101

Title: ACE2 improves right ventricular function in a pressure overload model.

Journal: PloS one20110101

Title: What is new for an old molecule? Systematic review and recommendations on the use of resveratrol.

Journal: PloS one20110101

Title: Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension.

Journal: Respiratory research20110101

Title: Novel interventional approaches for ALI/ARDS: cell-based gene therapy.

Journal: Mediators of inflammation20110101

Title: Angiogenesis gene expression in murine endothelial cells during post-pneumonectomy lung growth.

Journal: Respiratory research20110101

Title: Hypoxia-inducible factor-1 α/platelet derived growth factor axis in HIV-associated pulmonary vascular remodeling.

Journal: Respiratory research20110101

Title: Pulmonary oxidative stress is increased in cyclooxygenase-2 knockdown mice with mild pulmonary hypertension induced by monocrotaline.

Journal: PloS one20110101

Title: Increased oxidative stress and severe arterial remodeling induced by permanent high-flow challenge in experimental pulmonary hypertension.

Journal: Respiratory research20110101

Title: Krüppel-like factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension.

Journal: Respiratory research20110101

Title: Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells.

Journal: Respiratory research20110101

Title: VIP and endothelin receptor antagonist: an effective combination against experimental pulmonary arterial hypertension.

Journal: Respiratory research20110101

Title: Progenitor cells in pulmonary vascular remodeling.

Journal: Pulmonary circulation20110101

Title: Protein trafficking dysfunctions: Role in the pathogenesis of pulmonary arterial hypertension.

Journal: Pulmonary circulation20110101

Title: Combination use of sildenafil and simvastatin increases BMPR-II signal transduction in rats with monocrotaline-mediated pulmonary hypertension.

Journal: Pulmonary circulation20110101

Title: Transgenic mice over-expressing ET-1 in the endothelial cells develop systemic hypertension with altered vascular reactivity.

Journal: PloS one20110101

Title: Xanthine oxidase-derived ROS upregulate Egr-1 via ERK1/2 in PA smooth muscle cells; model to test impact of extracellular ROS in chronic hypoxia.

Journal: PloS one20110101

Title: The genetics of pulmonary arterial hypertension in the post-BMPR2 era.

Journal: Pulmonary circulation20110101

Title: Apelin and pulmonary hypertension.

Journal: Pulmonary circulation20110101

Title: Epigenetic mechanisms of pulmonary hypertension.

Journal: Pulmonary circulation20110101

Title: MicroRNAs-control of essential genes: Implications for pulmonary vascular disease.

Journal: Pulmonary circulation20110101

Title: Pharmacogenomics in pulmonary arterial hypertension: Toward a mechanistic, target-based approach to therapy.

Journal: Pulmonary circulation20110101

Title: Development of pulmonary arterial hypertension in mice over-expressing S100A4/Mts1 is specific to females.

Journal: Respiratory research20110101

Title: Treatment with LA-419 prevents monocrotaline-induced pulmonary hypertension and lung injury in the rat.

Journal: Proceedings of the Western Pharmacology Society20110101

Title: Reversible or irreversible remodeling in pulmonary arterial hypertension.

Journal: American journal of respiratory cell and molecular biology20101201

Title: Gene delivery of cytochrome p450 epoxygenase ameliorates monocrotaline-induced pulmonary artery hypertension in rats.

Journal: American journal of respiratory cell and molecular biology20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals20101201

Title: Urotensin II receptor antagonist attenuates monocrotaline-induced cardiac hypertrophy in rats.

Journal: American journal of physiology. Heart and circulatory physiology20101201

Title: [Comparison of the hepatic veno-occlusive disease models induced by gynura segetum, monocrotaline and cyclophosphamide].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology20101201

Title: Simvastatin, sildenafil and their combination in monocrotaline induced pulmonary arterial hypertension.

Journal: Korean circulation journal20101201

Title: Innate immunity in the therapeutic actions of endothelial progenitor cells in pulmonary hypertension.

Journal: American journal of respiratory cell and molecular biology20101101

Title: Effects of atorvastatin and L-arginine treatments on electrical field stimulation-mediated relaxations in pulmonary arterial rings of monocrotaline-induced pulmonary hypertensive rats.

Journal: Journal of cardiovascular pharmacology20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters20101101

Title: Synergistic therapeutic effects of 2-methoxyestradiol with either sildenafil or bosentan on amelioration of monocrotaline-induced pulmonary hypertension and vascular remodeling.

Journal: Journal of cardiovascular pharmacology20101101

Title: Effects of HIV protease inhibitors on progression of monocrotaline- and hypoxia-induced pulmonary hypertension in rats.

Journal: Circulation20101101

Title: Contribution of oxidative stress to pulmonary arterial hypertension.

Journal: World journal of cardiology20101026

Title: The angiotensin-converting enzyme 2/angiogenesis-(1-7)/Mas axis confers cardiopulmonary protection against lung fibrosis and pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine20101015

Title: Combination of sildenafil and simvastatin ameliorates monocrotaline-induced pulmonary hypertension in rats.

Journal: Pulmonary pharmacology & therapeutics20101001

Title: Fasudil reduces monocrotaline-induced pulmonary arterial hypertension: comparison with bosentan and sildenafil.

Journal: The European respiratory journal20101001

Title: Downregulation of oxytocin receptors in right ventricle of rats with monocrotaline-induced pulmonary hypertension.

Journal: Acta physiologica (Oxford, England)20101001

Title: Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension.

Journal: The European respiratory journal20101001

Title: The effects of atorvastatin on pulmonary arterial hypertension and expression of p38, p27, and Jab1 in rats.

Journal: International journal of molecular medicine20101001

Title: Differential cellular responses to protein adducts of naphthoquinone and monocrotaline pyrrole.

Journal: Chemical research in toxicology20100920

Title: Adrenergic receptor blockade reverses right heart remodeling and dysfunction in pulmonary hypertensive rats.

Journal: American journal of respiratory and critical care medicine20100901

Title: Analysis of heart rate variability in a rat model of induced pulmonary hypertension.

Journal: Medical engineering & physics20100901

Title: Validation of high-resolution echocardiography and magnetic resonance imaging vs. high-fidelity catheterization in experimental pulmonary hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology20100901

Title: Developing and characterizing a mouse model of hepatotoxicity using oral pyrrolizidine alkaloid (monocrotaline) administration, with potentiation of the liver injury by co-administration of LPS.

Journal: Natural product communications20100901

Title: Drug off-target effects predicted using structural analysis in the context of a metabolic network model.

Journal: PLoS computational biology20100901

Title: Gene expression of endothelin-1 and endothelin receptor a on monocrotaline-induced pulmonary hypertension in rats after bosentan treatment.

Journal: Korean circulation journal20100901

Title: Skeletal muscle proteins oxidation in chronic right heart failure in rats: can different beta-blockers prevent it to the same degree?

Journal: International journal of cardiology20100820

Title: Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension.

Journal: Science translational medicine20100811

Title: PRX-08066, a novel 5-hydroxytryptamine receptor 2B antagonist, reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats.

Journal: The Journal of pharmacology and experimental therapeutics20100801

Title: Consistency of predictive signature genes and classifiers generated using different microarray platforms.

Journal: The pharmacogenomics journal20100801

Title: Smad-dependent and smad-independent induction of id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo.

Journal: Circulation research20100723

Title: Determination of endothelin-1 in rats using a high-performance liquid chromatography coupled to electrospray tandem mass spectrometry.

Journal: Talanta20100715

Title: Analysis of responses to the Rho-kinase inhibitor Y-27632 in the pulmonary and systemic vascular bed of the rat.

Journal: American journal of physiology. Heart and circulatory physiology20100701

Title: Early inflammatory response during the development of right ventricular heart failure in a rat model.

Journal: European journal of heart failure20100701

Title: Smurf1 ubiquitin ligase causes downregulation of BMP receptors and is induced in monocrotaline and hypoxia models of pulmonary arterial hypertension.

Journal: Experimental biology and medicine (Maywood, N.J.)20100701

Title: A comparison of echocardiography to invasive measurement in the evaluation of pulmonary arterial hypertension in a rat model.

Journal: The international journal of cardiovascular imaging20100601

Title: L-arginine restores endothelial nitric oxide synthase-coupled activity and attenuates monocrotaline-induced pulmonary artery hypertension in rats.

Journal: American journal of physiology. Endocrinology and metabolism20100601

Title: Sildenafil limits monocrotaline-induced pulmonary hypertension in rats through suppression of pulmonary vascular remodeling.

Journal: Journal of cardiovascular pharmacology20100601

Title: The xanthine derivative KMUP-1 inhibits models of pulmonary artery hypertension via increased NO and cGMP-dependent inhibition of RhoA/Rho kinase.

Journal: British journal of pharmacology20100601

Title: KMUP-1 ameliorates monocrotaline-induced pulmonary arterial hypertension through the modulation of Ca2+ sensitization and K+-channel.

Journal: Life sciences20100508

Title: Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats.

Journal: Basic research in cardiology20100501

Title: Gene expression profile in flow-associated pulmonary arterial hypertension with neointimal lesions.

Journal: American journal of physiology. Lung cellular and molecular physiology20100401

Title: Pulmonary hypertension is ameliorated in mice deficient in thrombin-activatable fibrinolysis inhibitor.

Journal: Journal of thrombosis and haemostasis : JTH20100401

Title: Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline.

Journal: Arteriosclerosis, thrombosis, and vascular biology20100401

Title: Reduced mechanical efficiency of rat papillary muscle related to degree of hypertrophy of cardiomyocytes.

Journal: American journal of physiology. Heart and circulatory physiology20100401

Title: Sodium valproate, a histone deacetylase inhibitor, but not captopril, prevents right ventricular hypertrophy in rats.

Journal: Circulation journal : official journal of the Japanese Circulation Society20100401

Title: High-performance liquid chromatography electrospray ionization tandem mass spectrometry for the detection and quantitation of pyrrolizidine alkaloid-derived DNA adducts in vitro and in vivo.

Journal: Chemical research in toxicology20100315

Title: Glucuronidation, a new metabolic pathway for pyrrolizidine alkaloids.

Journal: Chemical research in toxicology20100315

Title: Cardiomyocyte-specific inactivation of thyroid hormone in pathologic ventricular hypertrophy: an adaptative response or part of the problem?

Journal: Heart failure reviews20100301

Title: Antioxidant treatment attenuates pulmonary arterial hypertension-induced heart failure.

Journal: American journal of physiology. Heart and circulatory physiology20100301

Title: A high-calorie diet attenuates cachexia and adipose tissue inflammation in monocrotaline-induced pulmonary hypertensive rats.

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology20100301

Title: [TRPC6 mediates the enhancements of pulmonary arterial tone and intracellular Ca2+ concentration of pulmonary arterial smooth muscle cells in pulmonary hypertension rats].

Journal: Sheng li xue bao : [Acta physiologica Sinica]20100225

Title: Resveratrol inhibits right ventricular hypertrophy induced by monocrotaline in rats.

Journal: Clinical and experimental pharmacology & physiology20100201

Title: Impaired vasoconstriction and nitric oxide-mediated relaxation in pulmonary arteries of hypoxia- and monocrotaline-induced pulmonary hypertensive rats.

Journal: The Journal of pharmacology and experimental therapeutics20100201

Title: The enzymatic degradation of hyaluronan is associated with disease progression in experimental pulmonary hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology20100201

Title: Progressive endothelial cell damage in an inflammatory model of pulmonary hypertension.

Journal: Experimental lung research20100201

Title: Heart failure increases atrogin-1 and MuRF1 gene expression in skeletal muscle with fiber type-specific atrophy.

Journal: Journal of molecular histology20100201

Title: Ghrelin and cardiovascular diseases.

Journal: Current cardiology reviews20100201

Title: Role of epidermal growth factor inhibition in experimental pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine20100115

Title: Retrorsine, but not monocrotaline, is a mechanism-based inactivator of P450 3A4.

Journal: Chemico-biological interactions20100105

Title: Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase-dependent nitric oxide generation.

Journal: Circulation20100105

Title: The effects and mechanisms of mycophenolate mofetil on pulmonary arterial hypertension in rats.

Journal: Rheumatology international20100101

Title: Poisoning of sheep by seeds of Crotalaria retusa: acquired resistance by continuous administration of low doses.

Journal: Toxicon : official journal of the International Society on Toxinology20100101

Title: Genotoxicity and morphological changes induced by the alkaloid monocrotaline, extracted from Crotalaria retusa, in a model of glial cells.

Journal: Toxicon : official journal of the International Society on Toxinology20100101

Title: Modulation of monocrotaline-induced cor pulmonale by grape juice.

Journal: Journal of cardiovascular pharmacology20100101

Title: The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle.

Journal: Journal of molecular medicine (Berlin, Germany)20100101

Title: Pulmonary hemodynamic response to acute combination and monotherapy with sildenafil and brain natriuretic peptide in rats with monocrotaline-induced pulmonary hypertension.

Journal: The American journal of the medical sciences20100101

Title: The extracellular signal-regulated kinase is involved in the effects of sildenafil on pulmonary vascular remodeling.

Journal: Cardiovascular therapeutics20100101

Title: Polyamine regulatory pathways as pharmacologic targets in pulmonary arterial hypertension.

Journal: Advances in experimental medicine and biology20100101

Title: The PPARbeta/delta agonist GW0742 relaxes pulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension.

Journal: PloS one20100101

Title: Novel approaches to treat experimental pulmonary arterial hypertension: a review.

Journal: Journal of biomedicine & biotechnology20100101

Title: Estrogen-induced relaxation of the rat tail artery is attenuated in rats with pulmonary hypertension.

Journal: Pharmacological reports : PR20100101

Title: Idiopathic pulmonary arterial hypertension.

Journal: Disease models & mechanisms20100101

Title: Flavin-dependent monooxygenases as a detoxification mechanism in insects: new insights from the arctiids (lepidoptera).

Journal: PloS one20100101

Title: Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELM alpha) recruits bone marrow-derived cells to the murine pulmonary vasculature.

Journal: PloS one20100101

Title: Dose-dependent therapeutic effects of 2-Methoxyestradiol on Monocrotaline-Induced pulmonary hypertension and vascular remodelling.

Journal: Prilozi20100101

Title: Involvement of asymmetric dimethylarginine and Rho kinase in the vascular remodeling in monocrotaline-induced pulmonary hypertension.

Journal: Vascular pharmacology20100101

Title: KMUP-1 inhibits pulmonary artery proliferation by targeting serotonin receptors/transporter and NO synthase, inactivating RhoA and suppressing AKT/ERK phosphorylation.

Journal: Vascular pharmacology20100101

Title: Systemic evaluation of platelet and leukocyte activation and interaction in a rat model of pulmonary arterial hypertension.

Journal: Cardiology20100101

Title: Genetics of pulmonary arterial hypertension: do the molecular findings have translational value?

Journal: F1000 biology reports20100101

Title: Rapid quantification of myocardial fibrosis: A new macro-based automated analysis.

Journal: Analytical cellular pathology (Amsterdam)20100101

Title: Interleukin-6 as a potential therapeutic target for pulmonary arterial hypertension.

Journal: International journal of rheumatology20100101

Title: Diesel engine exhaust initiates a sequence of pulmonary and cardiovascular effects in rats.

Journal: Journal of toxicology20100101

Title: Transforming growth factor-β inhibition attenuates pulmonary arterial hypertension in rats.

Journal: International journal of clinical and experimental medicine20100101

Title: Effects of atorvastatin and losartan on monocrotaline-induced pulmonary artery remodeling in rats.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993)20100101

Title: Biochemistry and occurrence of o-demethylation in plant metabolism.

Journal: Frontiers in physiology20100101

Title: Ayurveda and cancer.

Journal: Pharmacognosy research20100101

Title: Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure.

Journal: American journal of physiology. Lung cellular and molecular physiology20091201

Title: Effects of a pure alpha/beta-adrenergic receptor blocker on monocrotaline-induced pulmonary arterial hypertension with right ventricular hypertrophy in rats.

Journal: Circulation journal : official journal of the Japanese Circulation Society20091201

Title: Alterations in dystrophin-related glycoproteins in development of right ventricular failure in rats.

Journal: Journal of pharmacological sciences20091201

Title: Identification of genomic biomarkers for concurrent diagnosis of drug-induced renal tubular injury using a large-scale toxicogenomics database.

Journal: Toxicology20091109

Title: Senescent endothelial progenitor cells from dogs with pulmonary arterial hypertension: a before-after self-controlled study.

Journal: The journal of physiological sciences : JPS20091101

Title: Right ventricular pacing improves right heart function in experimental pulmonary arterial hypertension: a study in the isolated heart.

Journal: American journal of physiology. Heart and circulatory physiology20091101

Title: Allogenic stem cell therapy improves right ventricular function by improving lung pathology in rats with pulmonary hypertension.

Journal: American journal of physiology. Heart and circulatory physiology20091101

Title: Tadalafil, a long-acting inhibitor of PDE5, improves pulmonary hemodynamics and survival rate of monocrotaline-induced pulmonary artery hypertension in rats.

Journal: Journal of pharmacological sciences20091101

Title: [Testosterone therapy improves cardiac function of male rats with right heart failure].

Journal: Zhonghua nan ke xue = National journal of andrology20091101

Title: Intracellular glutathione plays important roles in pyrrolizidine alkaloids-induced growth inhibition on hepatocytes.

Journal: Environmental toxicology and pharmacology20091101

Title: Evaluation of the simvastatin effects in the treatment of pulmonary hypertension (PH).

Journal: Lijecnicki vjesnik20091101

Title: Golgi, trafficking, and mitosis dysfunctions in pulmonary arterial endothelial cells exposed to monocrotaline pyrrole and NO scavenging.

Journal: American journal of physiology. Lung cellular and molecular physiology20091001

Title: Effects of telmisartan on right ventricular remodeling induced by monocrotaline in rats.

Journal: Journal of pharmacological sciences20091001

Title: Time course and mechanisms of left ventricular systolic and diastolic dysfunction in monocrotaline-induced pulmonary hypertension.

Journal: Basic research in cardiology20090901

Title: Cirrhosis ameliorates monocrotaline-induced pulmonary hypertension in rats.

Journal: The European respiratory journal20090901

Title: Early combined treatment with cilostazol and bone marrow-derived endothelial progenitor cells markedly attenuates pulmonary arterial hypertension in rats.

Journal: The Journal of pharmacology and experimental therapeutics20090901

Title: Is resveratrol the magic bullet for pulmonary hypertension?

Journal: Hypertension (Dallas, Tex. : 1979)20090901

Title: Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats.

Journal: Hypertension (Dallas, Tex. : 1979)20090901

Title: Propylthiouracil attenuates monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: Circulation journal : official journal of the Japanese Circulation Society20090901

Title: Possible involvement of mitochondrial energy-producing ability in the development of right ventricular failure in monocrotaline-induced pulmonary hypertensive rats.

Journal: Journal of pharmacological sciences20090901

Title: Feeding deterrence and detrimental effects of pyrrolizidine alkaloids fed to honey bees (Apis mellifera).

Journal: Journal of chemical ecology20090901

Title: Monocrotaline-induced pulmonary hypertension in Wistar rats.

Journal: Current protocols in pharmacology20090901

Title: [Administrating bone marrow mesenchymal stem cells to treat the experimental pulmonary arterial hypertension in rats].

Journal: Zhonghua yi xue za zhi20090811

Title: Fluoxetine protects against monocrotaline-induced pulmonary arterial hypertension: potential roles of induction of apoptosis and upregulation of Kv1.5 channels in rats.

Journal: Clinical and experimental pharmacology & physiology20090801

Title: Bone marrow progenitor cells repair rat hepatic sinusoidal endothelial cells after liver injury.

Journal: Gastroenterology20090801

Title: Continuous fluoxetine administration prevents recurrence of pulmonary arterial hypertension and prolongs survival in rats.

Journal: Clinical and experimental pharmacology & physiology20090801

Title: Change in pharmacological effect of endothelin receptor antagonists in rats with pulmonary hypertension: role of ETB-receptor expression levels.

Journal: Pulmonary pharmacology & therapeutics20090801

Title: Prevention of pulmonary hypertension by Angiotensin-converting enzyme 2 gene transfer.

Journal: Hypertension (Dallas, Tex. : 1979)20090801

Title: Serial noninvasive assessment of apoptosis during right ventricular disease progression in rats.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine20090801

Title: Syngeneic bone marrow mononuclear cells improve pulmonary arterial hypertension through vascular endothelial growth factor upregulation.

Journal: The Annals of thoracic surgery20090801

Title: Alterations in pharmacological action of the right ventricle of monocrotaline-induced pulmonary hypertensive rats.

Journal: Biological & pharmaceutical bulletin20090801

Title: Retraction. Reliable experimental model of hepatic veno-occlusive disease caused by monocrotaline.

Journal: Hepatobiliary & pancreatic diseases international : HBPD INT20090801

Title: Temporal changes of angiopoietins and Tie2 expression in rat lungs after monocrotaline-induced pulmonary hypertension.

Journal: Comparative medicine20090801

Title: Discriminating pulmonary hypertension caused by monocrotaline toxicity from chronic hypoxia by near-infrared spectroscopy and multivariate methods of analysis.

Journal: Analytical biochemistry20090715

Title: Opposite effects of training in rats with stable and progressive pulmonary hypertension.

Journal: Circulation20090707

Title: Dehydromonocrotaline induces cyclosporine A-insensitive mitochondrial permeability transition/cytochrome c release.

Journal: Toxicon : official journal of the International Society on Toxinology20090701

Title: Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension in rats.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy20090701

Title: Analysis of pulmonary vasodilator responses to SB-772077-B [4-(7-((3-amino-1-pyrrolidinyl)carbonyl)-1-ethyl-1H-imidazo(4,5-c)pyridin-2-yl)-1,2,5-oxadiazol-3-amine], a novel aminofurazan-based Rho kinase inhibitor.

Journal: The Journal of pharmacology and experimental therapeutics20090701

Title: Effects of pyrrolizidine alkaloids on the performance of plant-parasitic and free-living nematodes.

Journal: Pest management science20090701

Title: Preventive effects of raloxifene, a selective estrogen receptor modulator, on monocrotaline-induced pulmonary hypertension in intact and ovariectomized female rats.

Journal: European journal of pharmacology20090701

Title: Effects of roflumilast, a phosphodiesterase-4 inhibitor, on hypoxia- and monocrotaline-induced pulmonary hypertension in rats.

Journal: The Journal of pharmacology and experimental therapeutics20090701

Title: Endothelin receptor blockade combined with phosphodiesterase-5 inhibition increases right ventricular mitochondrial capacity in pulmonary arterial hypertension.

Journal: American journal of physiology. Heart and circulatory physiology20090701

Title: Changes in pulmonary blood flow distribution in monocrotaline compared with hypoxia-induced models of pulmonary hypertension: assessed using synchrotron radiation.

Journal: Journal of hypertension20090701

Title: Molecular imaging of monocrotaline-induced pulmonary vascular disease with radiolabeled linear adrenomedullin.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine20090701

Title: [B-type natriuretic peptide (BNP) levels and the effects of carvedilol on BNP levels in juvenile rats with right heart failure].

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics20090701

Title: Progesterone inhibits vascular remodeling and attenuates monocrotaline-induced pulmonary hypertension in estrogen-deficient rats.

Journal: Prilozi20090701

Title: Marrow cell infusion attenuates vascular remodeling in a murine model of monocrotaline-induced pulmonary hypertension.

Journal: Stem cells and development20090601

Title: Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine20090601

Title: Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension.

Journal: American journal of physiology. Heart and circulatory physiology20090601

Title: Hepatic regeneration is decreased in a rat model of sinusoidal obstruction syndrome.

Journal: Journal of surgical oncology20090601

Title: Cardiac lesions induced by testosterone: protective effects of dexrazoxane and trimetazidine.

Journal: Cardiovascular toxicology20090601

Title: A novel therapeutic strategy for liver sinusoidal obstruction syndrome.

Journal: Journal of gastroenterology and hepatology20090601

Title: Dai-kenchu-to attenuates rat sinusoidal obstruction syndrome by inhibiting the accumulation of neutrophils in the liver.

Journal: Journal of gastroenterology and hepatology20090601

Title: Establishment of rat model of cardiopulmonary bypass in pulmonary hypertension.

Journal: Asian cardiovascular & thoracic annals20090601

Title: Simvastatin restores down-regulated GATA-6 expression in pulmonary hypertensive rats.

Journal: Experimental lung research20090601

Title: Nanoparticle-mediated delivery of nuclear factor kappaB decoy into lungs ameliorates monocrotaline-induced pulmonary arterial hypertension.

Journal: Hypertension (Dallas, Tex. : 1979)20090501

Title: A phosphodiesterase III inhibitor protects rat liver from sinusoidal obstruction syndrome through heme oxygenase-1 induction.

Journal: Annals of surgery20090501

Title: Chronic inhibition of phosphodiesterase 5 does not prevent pressure-overload-induced right-ventricular remodelling.

Journal: Cardiovascular research20090401

Title: [Simvastatin prevents the development of pulmonary hypertension in the rats through reduction of inflammation].

Journal: Zhonghua yi xue za zhi20090331

Title: Warning displays may function as honest signals of toxicity.

Journal: Proceedings. Biological sciences20090307

Title: Galphaq-protein carboxyl terminus imitation polypeptide (GCIP)-27 inhibits right ventricular hypertrophy induced by monocrotaline in rats.

Journal: Biological & pharmaceutical bulletin20090301

Title: Pulmonary hypertension modifies responsiveness of sinoatrial cells of rat hearts to adrenomimetics and activators of ATP-sensitive K+ channels in a gender-dependent way.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society20090301

Title: Low doses of monocrotaline in rats cause diminished bone marrow cellularity and compromised nitric oxide production by peritoneal macrophages.

Journal: Journal of immunotoxicology20090301

Title: 3-Hydroxy-3-methylglutaryl (HMG)-COA reductase inhibitors and phosphodiesterase type V inhibitors attenuate right ventricular pressure and remodeling in a rat model of pulmonary hypertension.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques20090204

Title: Altered bone morphogenetic protein and transforming growth factor-beta signaling in rat models of pulmonary hypertension: potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease.

Journal: Circulation20090203

Title: CPU0213, a non-selective ETA/ETB receptor antagonist, improves pulmonary arteriolar remodeling of monocrotaline-induced pulmonary hypertension in rats.

Journal: Clinical and experimental pharmacology & physiology20090201

Title: Molecular and electrical remodeling of L- and T-type Ca(2+) channels in rat right atrium with monocrotaline-induced pulmonary hypertension.

Journal: Circulation journal : official journal of the Japanese Circulation Society20090201

Title: Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by monocrotaline.

Journal: The American journal of pathology20090201

Title: Inhibition of the soluble epoxide hydrolase attenuates monocrotaline-induced pulmonary hypertension in rats.

Journal: Journal of hypertension20090201

Title: From arginine methylation to ADMA: a novel mechanism with therapeutic potential in chronic lung diseases.

Journal: BMC pulmonary medicine20090101

Title: Characterization of erectile function in monocrotaline-treated pulmonary hypertensive rats.

Journal: Journal of andrology20090101

Title: The remodeling of connexin in the hypertrophied right ventricular in pulmonary arterial hypertension and the effect of a dual ET receptor antagonist (bosentan).

Journal: Pathology, research and practice20090101

Title: Self-medication as adaptive plasticity: increased ingestion of plant toxins by parasitized caterpillars.

Journal: PloS one20090101

Title: Simvastatin ameliorates established pulmonary hypertension through a heme oxygenase-1 dependent pathway in rats.

Journal: Respiratory research20090101

Title: Serum VEGF levels are related to the presence of pulmonary arterial hypertension in systemic sclerosis.

Journal: BMC pulmonary medicine20090101

Title: Inhaled iloprost for the control of pulmonary hypertension.

Journal: Vascular health and risk management20090101

Title: Discernment of possible mechanisms of hepatotoxicity via biological processes over-represented by co-expressed genes.

Journal: BMC genomics20090101

Title: Divergent cardiopulmonary actions of heme oxygenase enzymatic products in chronic hypoxia.

Journal: PloS one20090101

Title: Treatment of pediatric pulmonary hypertension.

Journal: Vascular health and risk management20090101

Title: Caveolin-1 Expression and Hemodynamics in COPD Patients.

Journal: The open respiratory medicine journal20090101

Title: Protective effects of hydroalcoholic extract from rhizomes of Cynodon dactylon (L.) Pers. on compensated right heart failure in rats.

Journal: BMC complementary and alternative medicine20090101

Title: RhoA/Rho-kinase signaling: a therapeutic target in pulmonary hypertension.

Journal: Vascular health and risk management20090101

Title: Pressure overload-induced right ventricular failure is associated with re-expression of myocardial tenascin-C and elevated plasma tenascin-C levels.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20090101

Title: Update on pulmonary hypertension complicating chronic obstructive pulmonary disease.

Journal: International journal of chronic obstructive pulmonary disease20090101

Title: Inhibition of SOC/Ca2+/NFAT pathway is involved in the anti-proliferative effect of sildenafil on pulmonary artery smooth muscle cells.

Journal: Respiratory research20090101

Title: Anti-TNF treatment reduces rat skeletal muscle wasting in monocrotaline-induced cardiac cachexia.

Journal: Journal of applied physiology (Bethesda, Md. : 1985)20081201

Title: Upregulation of GLUT-4 in right ventricle of rats with monocrotaline-induced pulmonary hypertension.

Journal: Medical science monitor : international medical journal of experimental and clinical research20081201

Title: Captopril attenuates matrix metalloproteinase-2 and -9 in monocrotaline-induced right ventricular hypertrophy in rats.

Journal: Journal of pharmacological sciences20081201

Title: Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling.

Journal: Circulation20081111

Title: Effects of monocrotaline on energy metabolism in the rat liver.

Journal: Toxicology letters20081110

Title: Analysis of pulmonary vasodilator responses to the Rho-kinase inhibitor fasudil in the anesthetized rat.

Journal: American journal of physiology. Lung cellular and molecular physiology20081101

Title: Endothelin-3-dependent pulmonary vasoconstriction in monocrotaline-induced pulmonary arterial hypertension.

Journal: Peptides20081101

Title: Depletion of the ATPase NSF from Golgi membranes with hypo-S-nitrosylation of vasorelevant proteins in endothelial cells exposed to monocrotaline pyrrole.

Journal: American journal of physiology. Heart and circulatory physiology20081101

Title: Hemin treatment abrogates monocrotaline-induced pulmonary hypertension.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates))20081101

Title: Novel approach with intratracheal administration of microgelatin hydrogel microspheres incorporating basic fibroblast growth factor for rescue of rats with monocrotaline-induced pulmonary hypertension.

Journal: The Journal of thoracic and cardiovascular surgery20081101

Title: Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension.

Journal: British journal of pharmacology20081001

Title: Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.

Journal: The European respiratory journal20081001

Title: Effects of endogenous sulfur dioxide on monocrotaline-induced pulmonary hypertension in rats.

Journal: Acta pharmacologica Sinica20081001

Title: m-Nisoldipine attenuates monocrotaline-induced pulmonary hypertension by suppressing 5-HT/ERK MAPK pathway.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20081001

Title: Involvement of Bcl-xL degradation and mitochondrial-mediated apoptotic pathway in pyrrolizidine alkaloids-induced apoptosis in hepatocytes.

Journal: Toxicology and applied pharmacology20080915

Title: Thymulin inhibits monocrotaline-induced pulmonary hypertension modulating interleukin-6 expression and suppressing p38 pathway.

Journal: Endocrinology20080901

Title: Celecoxib but not the combination of celecoxib+atorvastatin prevents the development of monocrotaline-induced pulmonary hypertension in the rat.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20080901

Title: A long-acting and highly selective prostacyclin receptor agonist prodrug, 2-{4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide (NS-304), ameliorates rat pulmonary hypertension with unique relaxant responses of its active form, {4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}acetic acid (MRE-269), on rat pulmonary artery.

Journal: The Journal of pharmacology and experimental therapeutics20080901

Title: Effects of a chronic exercise training protocol on oxidative stress and right ventricular hypertrophy in monocrotaline-treated rats.

Journal: Clinical and experimental pharmacology & physiology20080801

Title: Monocrotaline pyrrol is cytotoxic and alters the patterns of GFAP expression on astrocyte primary cultures.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20080801

Title: Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice.

Journal: American journal of physiology. Heart and circulatory physiology20080801

Title: Total ginsenosides inhibit the right ventricular hypertrophy induced by monocrotaline in rats.

Journal: Biological & pharmaceutical bulletin20080801

Title: Reliable experimental model of hepatic veno-occlusive disease caused by monocrotaline.

Journal: Hepatobiliary & pancreatic diseases international : HBPD INT20080801

Title: Final report on carcinogens background document for riddelliine.

Journal: Report on carcinogens background document for [substance name]20080801

Title: Role of the prostanoid EP4 receptor in iloprost-mediated vasodilatation in pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine20080715

Title: Reduced number and activity of circulating endothelial progenitor cells in patients with idiopathic pulmonary arterial hypertension.

Journal: Respiratory medicine20080701

Title: Involvement of RhoA/Rho kinase signaling in protection against monocrotaline-induced pulmonary hypertension in pneumonectomized rats by dehydroepiandrosterone.

Journal: American journal of physiology. Lung cellular and molecular physiology20080701

Title: Pyrrolidine dithiocarbamate restores endothelial cell membrane integrity and attenuates monocrotaline-induced pulmonary artery hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology20080601

Title: Down-regulation of MyoD gene expression in rat diaphragm muscle with heart failure.

Journal: International journal of experimental pathology20080601

Title: Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, heliotrine.

Journal: Toxicology letters20080505

Title: Skeletal muscle myofibrillar protein oxidation and exercise capacity in heart failure.

Journal: Basic research in cardiology20080501

Title: Cilostazol therapy attenuates monocrotaline-induced pulmonary arterial hypertension in rat model.

Journal: Circulation journal : official journal of the Japanese Circulation Society20080501

Title: [Contribution of circulating platelet and leukocyte activation to primary pulmonary hypertension in rats].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences20080501

Title: [Quantitative and functional changes of circulating endothelial progenitor cells in dogs with dehydromonocrotaline-induced pulmonary artery hypertension].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases20080501

Title: [Expression of connective tissue growth factor and its down-regulation by simvastatin administration in pulmonary hypertensive rats].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics20080501

Title: Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine20080415

Title: Bone marrow progenitor cells contribute to repair and remodeling of the lung and heart in a rat model of progressive pulmonary hypertension.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20080401

Title: Metabolic activation of retronecine and retronecine N-oxide - formation of DHP-derived DNA adducts.

Journal: Toxicology and industrial health20080401

Title: Carnitine-mediated improved response to erythropoietin involves induction of haem oxygenase-1: studies in humans and in an animal model.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20080301

Title: Partial reversal of experimental pulmonary hypertension by phosphodiesterase-3/4 inhibition.

Journal: The European respiratory journal20080301

Title: Cytoplasmic provenance of STAT3 and PY-STAT3 in the endolysosomal compartments in pulmonary arterial endothelial and smooth muscle cells: implications in pulmonary arterial hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology20080301

Title: Autologous transplantation of bone marrow-derived endothelial progenitor cells attenuates monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: Critical care medicine20080301

Title: Pulmonary hypertension associated with COPD.

Journal: International journal of chronic obstructive pulmonary disease20080301

Title: Effects of TNF-alpha blockade in monocrotaline-induced pulmonary hypertension.

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology20080301

Title: A refined radio-telemetry technique to monitor right ventricle or pulmonary artery pressures in rats: a useful tool in pulmonary hypertension research.

Journal: Pflugers Archiv : European journal of physiology20080201

Title: Rosuvastatin provides pleiotropic protection against pulmonary hypertension, right ventricular hypertrophy, and coronary endothelial dysfunction in rats.

Journal: American journal of physiology. Heart and circulatory physiology20080201

Title: Smad signaling in the rat model of monocrotaline pulmonary hypertension.

Journal: Toxicologic pathology20080201

Title: Gene transfer of extracellular superoxide dismutase ameliorates pulmonary hypertension in rats.

Journal: American journal of respiratory and critical care medicine20080115

Title: Single injection of a sustained-release prostacyclin analog improves pulmonary hypertension in rats.

Journal: American journal of respiratory and critical care medicine20080115

Title: Effects of erythropoietin on advanced pulmonary vascular remodelling.

Journal: The European respiratory journal20080101

Title: Hepatocyte transplantation and drug-induced perturbations in liver cell compartments.

Journal: Hepatology (Baltimore, Md.)20080101

Title: Evaluation of olmesartan medoxomil in the rat monocrotaline model of pulmonary hypertension.

Journal: Journal of cardiovascular pharmacology20080101

Title: 2-Ethoxyestradiol is antimitogenic and attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling.

Journal: Vascular pharmacology20080101

Title: Rho kinase-mediated vasoconstriction in rat models of pulmonary hypertension.

Journal: Methods in enzymology20080101

Title: CD45RB is a novel molecular therapeutic target to inhibit Abeta peptide-induced microglial MAPK activation.

Journal: PloS one20080101

Title: Genes related to apoptosis predict necrosis of the liver as a phenotype observed in rats exposed to a compendium of hepatotoxicants.

Journal: BMC genomics20080101

Title: Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype.

Journal: Genome biology20080101

Title: Effects of selective and unselective endothelin-receptor antagonists on prostacyclin synthase gene expression in experimental pulmonary hypertension.

Journal: Scandinavian journal of clinical and laboratory investigation20080101

Title: Biomarkers for ragwort poisoning in horses: identification of protein targets.

Journal: BMC veterinary research20080101

Title: Gene set enrichment analysis for non-monotone association and multiple experimental categories.

Journal: BMC bioinformatics20080101

Title: Use of bioluminescent imaging to assay the transplantation of immortalized human fetal hepatocytes into mice.

Journal: Cell transplantation20080101

Title: Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury.

Journal: BMC pulmonary medicine20080101

Title: [Comparative characteristics of some pharmacological models of chronic heart failure].

Journal: Eksperimental'naia i klinicheskaia farmakologiia20080101

Title: In vitro metabolism of isoline, a pyrrolizidine alkaloid from Ligularia duciformis, by rodent liver microsomal esterase and enhanced hepatotoxicity by esterase inhibitors.

Journal: Drug metabolism and disposition: the biological fate of chemicals20071001

Title: Dehydromonocrotaline inhibits mitochondrial complex I. A potential mechanism accounting for hepatotoxicity of monocrotaline.

Journal: Toxicon : official journal of the International Society on Toxinology20071001

Title: Oral sildenafil prevents and reverses the development of pulmonary hypertension in monocrotaline-treated rats.

Journal: Interactive cardiovascular and thoracic surgery20071001

Title: Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study.

Journal: American journal of physiology. Lung cellular and molecular physiology20071001

Title: The antiproliferative effect of sildenafil on pulmonary artery smooth muscle cells is mediated via upregulation of mitogen-activated protein kinase phosphatase-1 and degradation of extracellular signal-regulated kinase 1/2 phosphorylation.

Journal: Anesthesia and analgesia20071001

Title: A nuclear factor-kappaB inhibitor pyrrolidine dithiocarbamate ameliorates pulmonary hypertension in rats.

Journal: Chest20071001

Title: [Effect of triptolide on the expression of matrix metalloproteinases 2 and 9 in lungs of experimental pulmonary hypertension].

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics20071001

Title: Interleukin-10 expression mediated by an adeno-associated virus vector prevents monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: Circulation research20070928

Title: Serotonin transporter protein in pulmonary hypertensive rats treated with atorvastatin.

Journal: American journal of physiology. Lung cellular and molecular physiology20070901

Title: Right-ventricular failure is associated with increased mitochondrial complex II activity and production of reactive oxygen species.

Journal: Cardiovascular research20070901

Title: Plexiform-like lesions and increased tissue factor expression in a rat model of severe pulmonary arterial hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology20070901

Title: Preservation of diastolic function in monocrotaline-induced right ventricular hypertrophy in rats.

Journal: American journal of physiology. Heart and circulatory physiology20070901

Title: Adenoassociated virus-mediated prostacyclin synthase expression prevents pulmonary arterial hypertension in rats.

Journal: Hypertension (Dallas, Tex. : 1979)20070901

Title: Rodent models of PAH: are we there yet?

Journal: American journal of physiology. Lung cellular and molecular physiology20070901

Title: Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1.

Journal: PLoS medicine20070901

Title: [Effect of triptolide on the development of monocrotaline-induced pulmonary hypertension in pneumonectomized rat].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition20070901

Title: Protective effect of Adhatoda vascia Nees against radiation-induced damage at cellular, biochemical and chromosomal levels in Swiss albino mice.

Journal: Evidence-based complementary and alternative medicine : eCAM20070901

Title: Early changes in rat hearts with developing pulmonary arterial hypertension can be detected with three-dimensional electrocardiography.

Journal: American journal of physiology. Heart and circulatory physiology20070801

Title: Effects of combined therapy with a Rho-kinase inhibitor and prostacyclin on monocrotaline-induced pulmonary hypertension in rats.

Journal: Journal of cardiovascular pharmacology20070801

Title: Frequency-dependent myofilament Ca2+ desensitization in failing rat myocardium.

Journal: The Journal of physiology20070715

Title: Dysfunctional intracellular trafficking in the pathobiology of pulmonary arterial hypertension.

Journal: American journal of respiratory cell and molecular biology20070701

Title: Decreased left ventricular function, myocarditis, and coronary arteriolar medial thickening following monocrotaline administration in adult rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985)20070701

Title: Pulmonary arterial hypertension: a disease of tethers, SNAREs and SNAPs?

Journal: American journal of physiology. Heart and circulatory physiology20070701

Title: Amlodipine prevents monocrotaline-induced pulmonary arterial hypertension and prolongs survival in rats independent of blood pressure lowering.

Journal: Clinical and experimental pharmacology & physiology20070701

Title: Comparison of lung proteome profiles in two rodent models of pulmonary arterial hypertension.

Journal: Proteomics20070701

Title: Cardiac sympathetic rejuvenation: a link between nerve function and cardiac hypertrophy.

Journal: Circulation research20070622

Title: Impaired NO-mediated vasodilation with increased superoxide but robust EDHF function in right ventricular arterial microvessels of pulmonary hypertensive rats.

Journal: American journal of physiology. Heart and circulatory physiology20070601

Title: Roles of accumulated endogenous nitric oxide synthase inhibitors, enhanced arginase activity, and attenuated nitric oxide synthase activity in endothelial cells for pulmonary hypertension in rats.

Journal: American journal of physiology. Lung cellular and molecular physiology20070601

Title: Monocrotaline pyrrole induces Smad nuclear accumulation and altered signaling expression in human pulmonary arterial endothelial cells.

Journal: Vascular pharmacology20070601

Title: Dysfunction of Golgi tethers, SNAREs, and SNAPs in monocrotaline-induced pulmonary hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology20070601

Title: The transforming growth factor-beta/Smad2,3 signalling axis is impaired in experimental pulmonary hypertension.

Journal: The European respiratory journal20070601

Title: [Changes of pulmonary artery protein kinase C activity in rats with chronic inflammatory pulmonary hypertension].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University20070601

Title: [Effect of simvastatin on rat pulmonary hypertension induced by high pulmonary blood flow and injected monocrotaline].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition20070601

Title: Inhibitory effect of ginsenoside Rb1 on cardiac hypertrophy induced by monocrotaline in rat.

Journal: Journal of ethnopharmacology20070522

Title: Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension.

Journal: Arteriosclerosis, thrombosis, and vascular biology20070501

Title: [Expression and activity of RhoA/Rho kinase in remodeling of high blood flow pulmonary vessels.].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics20070501

Title: Overexpression of human bone morphogenetic protein receptor 2 does not ameliorate monocrotaline pulmonary arterial hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology20070401

Title: Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling.

Journal: American journal of physiology. Lung cellular and molecular physiology20070401

Title: Recent progress in the treatment of pulmonary arterial hypertension: expectation for rho-kinase inhibitors.

Journal: The Tohoku journal of experimental medicine20070401

Title: [Animal models of pulmonary arterial hypertension].

Journal: Revue des maladies respiratoires20070401

Title: [Changes of thrombomodulin in rats with pulmonary hypertension induced by monocrotaline].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics20070401

Title: Aberrant cytoplasmic sequestration of eNOS in endothelial cells after monocrotaline, hypoxia, and senescence: live-cell caveolar and cytoplasmic NO imaging.

Journal: American journal of physiology. Heart and circulatory physiology20070301

Title: Dendritic cell recruitment in lesions of human and experimental pulmonary hypertension.

Journal: The European respiratory journal20070301

Title: Internalization and dephosphorylation of connexin43 in hypertrophied right ventricles of rats with pulmonary hypertension.

Journal: Circulation journal : official journal of the Japanese Circulation Society20070301

Title: Bone marrow-derived hepatic oval cells differentiate into hepatocytes in 2-acetylaminofluorene/partial hepatectomy-induced liver regeneration.

Journal: Gastroenterology20070301

Title: [Pulmonary hypertension treatment: future prospects].

Journal: Archivos de bronconeumologia20070301

Title: Intratracheal mesenchymal stem cell administration attenuates monocrotaline-induced pulmonary hypertension and endothelial dysfunction.

Journal: American journal of physiology. Heart and circulatory physiology20070201

Title: Acute vasodilator effect of fasudil, a Rho-kinase inhibitor, in monocrotaline-induced pulmonary hypertension in rats.

Journal: Journal of cardiovascular pharmacology20070201

Title: Diverse contribution of bone marrow-derived cells to vascular remodeling associated with pulmonary arterial hypertension and arterial neointimal formation.

Journal: Circulation20070130

Title: Inhibition of rho kinase attenuates high flow induced pulmonary hypertension in rats.

Journal: Chinese medical journal20070105

Title: Right ventricular hypertrophy causes impairment of left ventricular diastolic function in the rat.

Journal: Basic research in cardiology20070101

Title: Propofol increases pulmonary vascular resistance during alpha-adrenoreceptor activation in normal and monocrotaline-induced pulmonary hypertensive rats.

Journal: Anesthesia and analgesia20070101

Title: Granulocyte colony-stimulating factor prevents progression of monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: Circulation journal : official journal of the Japanese Circulation Society20070101

Title: Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice.

Journal: Respiratory research20070101

Title: Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice.

Journal: Respiratory research20070101

Title: Activity of endothelium-derived hyperpolarizing factor is augmented in monocrotaline-induced pulmonary hypertension of rat lungs.

Journal: Journal of vascular research20070101

Title: Effects on cytokines and histology by treatment with the ACE inhibitor captopril and the antioxidant retinoic acid in the monocrotaline model of experimentally induced lung fibrosis.

Journal: Current pharmaceutical design20070101

Title: The role of peroxisome proliferator-activated receptors in pulmonary vascular disease.

Journal: PPAR research20070101

Title: Characterisation of a rat model of pulmonary arterial hypertension.

Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese20070101

Title: PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice.

Journal: BMC cell biology20070101

Title: Activation of signaling molecules and matrix metalloproteinases in right ventricular myocardium of rats with pulmonary hypertension.

Journal: Pathology, research and practice20070101

Title: Comparison of gene expression profiles altered by comfrey and riddelliine in rat liver.

Journal: BMC bioinformatics20070101

Title: Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats.

Journal: BMC bioinformatics20070101

Title: [Chronic administration of serotonin transporter inhibitor (fluoxetine) decreases monocrotaline-induced pulmonary hypertension in rats].

Journal: Eksperimental'naia i klinicheskaia farmakologiia20070101

Title: [Chronic blockade of serotonin transporter promotes restoration of the sensitivity of pulmonary vessels to vasoconstrictive agents in rats with monocrotaline-induced pulmonary hypertension].

Journal: Eksperimental'naia i klinicheskaia farmakologiia20070101

Title: Modeling inflammation-drug interactions in vitro: a rat Kupffer cell-hepatocyte coculture system.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20061201

Title: 2-Methoxyestradiol mediates the protective effects of estradiol in monocrotaline-induced pulmonary hypertension.

Journal: Vascular pharmacology20061201

Title: Sleeping Beauty-mediated eNOS gene therapy attenuates monocrotaline-induced pulmonary hypertension in rats.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20061201

Title: The protective effect of HMG-CoA reductase inhibitors against monocrotaline-induced pulmonary hypertension in the rat might not be a class effect: comparison of pravastatin and atorvastatin.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20061201

Title: Monocrotaline promotes transplanted cell engraftment and advances liver repopulation in rats via liver conditioning.

Journal: Hepatology (Baltimore, Md.)20061201

Title: Heart failure alters matrix metalloproteinase gene expression and activity in rat skeletal muscle.

Journal: International journal of experimental pathology20061201

Title: Sildenafil in the treatment of pulmonary hypertension.

Journal: Vascular health and risk management20061201

Title: Prostacyclin therapy increases right ventricular capillarisation in a model for flow-associated pulmonary hypertension.

Journal: European journal of pharmacology20061107

Title: Allicin in garlic protects against coronary endothelial dysfunction and right heart hypertrophy in pulmonary hypertensive rats.

Journal: American journal of physiology. Heart and circulatory physiology20061101

Title: Characterization of right ventricular function after monocrotaline-induced pulmonary hypertension in the intact rat.

Journal: American journal of physiology. Heart and circulatory physiology20061101

Title: Sertraline protects against monocrotaline-induced pulmonary hypertension in rats.

Journal: Clinical and experimental pharmacology & physiology20061101

Title: Protective role of protein C inhibitor in monocrotaline-induced pulmonary hypertension.

Journal: Journal of thrombosis and haemostasis : JTH20061101

Title: Treprostinil in advanced experimental pulmonary hypertension: beneficial outcome without reversed pulmonary vascular remodeling.

Journal: Journal of cardiovascular pharmacology20061101

Title: [Expression of GATA6 gene in lung tissue of rat with pulmonary hypertension].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition20061101

Title: Mycophenolate mofetil attenuates pulmonary arterial hypertension in rats.

Journal: Biochemical and biophysical research communications20061020

Title: ROCK controls matrix synthesis in vascular smooth muscle cells: coupling vasoconstriction to vascular remodeling.

Journal: Circulation research20061013

Title: Myocardial dysfunction and neurohumoral activation without remodeling in left ventricle of monocrotaline-induced pulmonary hypertensive rats.

Journal: American journal of physiology. Heart and circulatory physiology20061001

Title: Major components in the hairpencil secretion of a butterfly, Euploea mulciber (Lepidoptera, Danaidae): their origins and male behavioral responses to pyrrolizidine alkaloids.

Journal: Journal of insect physiology20061001

Title: Sequence of echocardiographic changes during development of right ventricular failure in rat.

Journal: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography20061001

Title: Reduced inotropic effect of nifekalant in failing hearts in rats.

Journal: The Journal of pharmacology and experimental therapeutics20060901

Title: The HMG-CoA reductase inhibitor, pravastatin, prevents the development of monocrotaline-induced pulmonary hypertension in the rat through reduction of endothelial cell apoptosis and overexpression of eNOS.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20060901

Title: How valid are animal models to evaluate treatments for pulmonary hypertension?

Journal: Naunyn-Schmiedeberg's archives of pharmacology20060901

Title: Upregulated neurohumoral factors are associated with left ventricular remodeling and poor prognosis in rats with monocrotaline-induced pulmonary arterial hypertension.

Journal: Circulation journal : official journal of the Japanese Circulation Society20060901

Title: Short-term administration of a cell-permeable caveolin-1 peptide prevents the development of monocrotaline-induced pulmonary hypertension and right ventricular hypertrophy.

Journal: Circulation20060829

Title: Anticoagulation and inhibition of nitric oxide synthase influence hepatic hypoxia after monocrotaline exposure.

Journal: Toxicology20060815

Title: Microvascular regeneration in established pulmonary hypertension by angiogenic gene transfer.

Journal: American journal of respiratory cell and molecular biology20060801

Title: Implantation of mesenchymal stem cells overexpressing endothelial nitric oxide synthase improves right ventricular impairments caused by pulmonary hypertension.

Journal: Circulation20060704

Title: Inotropic and lusitropic effects of ghrelin and their modulation by the endocardial endothelium, NO, prostaglandins, GHS-R1a and KCa channels.

Journal: Peptides20060701

Title: Role of chymase-dependent angiotensin II formation in monocrotaline-induced pulmonary hypertensive rats.

Journal: Pediatric research20060701

Title: Myocyte morphological characteristics differ between the phases of pulmonary hypertension-induced ventricular hypertrophy and failure.

Journal: International heart journal20060701

Title: Remodeling excitation-contraction coupling of hypertrophied ventricular myocytes is dependent on T-type calcium channels expression.

Journal: Biochemical and biophysical research communications20060630

Title: Discordant regulatory changes in monocrotaline-induced megalocytosis of lung arterial endothelial and alveolar epithelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology20060601

Title: Bosentan, sildenafil, and their combination in the monocrotaline model of pulmonary hypertension in rats.

Journal: Experimental biology and medicine (Maywood, N.J.)20060601

Title: Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension.

Journal: Circulation research20060526

Title: Upregulation of profilin, cofilin-2 and LIMK2 in cultured pulmonary artery smooth muscle cells and in pulmonary arteries of monocrotaline-treated rats.

Journal: Vascular pharmacology20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: Monocrotaline pyrrole-induced megalocytosis of lung and breast epithelial cells: Disruption of plasma membrane and Golgi dynamics and an enhanced unfolded protein response.

Journal: Toxicology and applied pharmacology20060315

Title: [The change of mast cells and macrophages in the lung of rat with pulmonary hypertension].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition20060301

Title: Selective right, but not left, coronary endothelial dysfunction precedes development of pulmonary hypertension and right heart hypertrophy in rats.

Journal: American journal of physiology. Heart and circulatory physiology20060201

Title: Activation of soluble guanylate cyclase reverses experimental pulmonary hypertension and vascular remodeling.

Journal: Circulation20060117

Title: Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, lasiocarpine.

Journal: Cancer letters20060108

Title: Heme oxygenase-1 mediates the protective effects of rapamycin in monocrotaline-induced pulmonary hypertension.

Journal: Laboratory investigation; a journal of technical methods and pathology20060101

Title: Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cells.

Journal: Respiratory research20060101

Title: Genistein, a phytoestrogen, attenuates monocrotaline-induced pulmonary hypertension.

Journal: Respiration; international review of thoracic diseases20060101

Title: Ghrelin reverses molecular, structural and hemodynamic alterations of the right ventricle in pulmonary hypertension.

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology20060101

Title: Analysis of gene expression changes in relation to toxicity and tumorigenesis in the livers of Big Blue transgenic rats fed comfrey (Symphytum officinale).

Journal: BMC bioinformatics20060101

Title: Hypoxia and dehydroepiandrosterone in old age: a mouse survival study.

Journal: Respiratory research20060101

Title: Cardiac hypertrophy induced by prostaglandin F(2alpha) may be mediated by calcineurin signal transduction pathway in rats.

Journal: Sheng li xue bao : [Acta physiologica Sinica]20051225

Title: A long-acting prostacyclin agonist with thromboxane inhibitory activity for pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine20051215

Title: Doppler tissue imaging in assessment of pulmonary hypertension-induced right ventricle dysfunction.

Journal: American journal of physiology. Heart and circulatory physiology20051201

Title: Monocrotaline pyrrole targets proteins with and without cysteine residues in the cytosol and membranes of human pulmonary artery endothelial cells.

Journal: Proteomics20051101

Title: CPU 86017, p-chlorobenzyltetrahydroberberine chloride, attenuates monocrotaline-induced pulmonary hypertension by suppressing endothelin pathway.

Journal: Acta pharmacologica Sinica20051101

Title: Estradiol metabolites attenuate monocrotaline-induced pulmonary hypertension in rats.

Journal: Journal of cardiovascular pharmacology20051001

Title: Effects of nicorandil on monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: Journal of cardiovascular pharmacology20051001

Title: Contractile effects of Ghrelin and expression of its receptor GHS-R1a in normal and hypertrophic myocardium.

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology20051001

Title: Excess l-arginine restores endothelium-dependent relaxation impaired by monocrotaline pyrrole.

Journal: Toxicology and applied pharmacology20050915

Title: Mechanical stress-dependent transcriptional regulation of sarcolipin gene in the rodent atrium.

Journal: Biochemical and biophysical research communications20050902

Title: The role of increased pulmonary blood flow in pulmonary arterial hypertension.

Journal: The European respiratory journal20050901

Title: Metabolic activation of the tumorigenic pyrrolizidine alkaloid, monocrotaline, leading to DNA adduct formation in vivo.

Journal: Cancer letters20050808

Title: Inhaled iloprost reverses vascular remodeling in chronic experimental pulmonary hypertension.

Journal: American journal of respiratory and critical care medicine20050801

Title: [The effect of compound macrostem onion capsule on metabolism of arachidonic acid in a rat model of monocrotaline-induced pulmonary artery hypertension].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases20050801

Title: Epidermal growth factor receptor blockade mediates smooth muscle cell apoptosis and improves survival in rats with pulmonary hypertension.

Journal: Circulation20050719

Title: Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20050701

Title: Immunohistochemical determination of cytosolic cytochrome C concentration in cardiomyocytes.

Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society20050701

Title: Development of occlusive neointimal lesions in distal pulmonary arteries of endothelin B receptor-deficient rats: a new model of severe pulmonary arterial hypertension.

Journal: Circulation20050607

Title: Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats.

Journal: Circulation20050531

Title: Microarray analysis reveals pivotal divergent mRNA expression profiles early in the development of either compensated ventricular hypertrophy or heart failure.

Journal: Physiological genomics20050511

Title: ClC-3 chloride channel is upregulated by hypertrophy and inflammation in rat and canine pulmonary artery.

Journal: British journal of pharmacology20050501

Title: Skeletal muscle myofibrillar protein oxidation in heart failure and the protective effect of Carvedilol.

Journal: Journal of molecular and cellular cardiology20050501

Title: Macro- and micropulmonary hemodynamic changes to nitric oxide blockade in monocrotaline-induced pulmonary hypertension in rats--an in vivo approach.

Journal: Journal of the Formosan Medical Association = Taiwan yi zhi20050501

Title: [Effects of peroxisome proliferator-activated receptor gamma ligands on monocrotaline-induced pulmonary hypertension in rats].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society20050501

Title: Metabolic activation of the tumorigenic pyrrolizidine alkaloid, retrorsine, leading to DNA adduct formation in vivo.

Journal: International journal of environmental research and public health20050501

Title: Monocrotaline pyrrole-induced endothelial cell megalocytosis involves a Golgi blockade mechanism.

Journal: American journal of physiology. Cell physiology20050401

Title: Pressure overload and neurohumoral activation differentially affect the myocardial proteome.

Journal: Proteomics20050401

Title: Decreased vagal control over heart rate in rats with right-sided congestive heart failure: downregulation of neuronal nitric oxide synthase.

Journal: Circulation journal : official journal of the Japanese Circulation Society20050401

Title: Animal models of heart failure: what is new?

Journal: The Annals of thoracic surgery20050401

Title: Simvastatin treatment of pulmonary hypertension: an observational case series.

Journal: Chest20050401

Title: Do naïve ruminants degrade alkaloids in the rumen?

Journal: Journal of chemical ecology20050401

Title: Differential utilization of pyrrolizidine alkaloids by males of a danaid butterfly, Parantica sita, for the production of danaidone in the alar scent organ.

Journal: Journal of chemical ecology20050401

Title: Increased pulmonary heme oxygenase-1 and delta-aminolevulinate synthase expression in monocrotaline-induced pulmonary hypertension.

Journal: Current neurovascular research20050401

Title: Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid.

Journal: Toxicology letters20050315

Title: Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: efficacy of combined cell and eNOS gene therapy in established disease.

Journal: Circulation research20050304

Title: Acute intoxication by Crotalaria retusa in sheep.

Journal: Toxicon : official journal of the International Society on Toxinology20050301

Title: Monocrotaline-induced pulmonary hypertension correlates with upregulation of connective tissue growth factor expression in the lung.

Journal: Experimental & molecular medicine20050227

Title: Gene transfer of a TIE2 receptor antagonist prevents pulmonary hypertension in rodents.

Journal: The Journal of thoracic and cardiovascular surgery20050201

Title: [Decrease of nitric oxide (NO)-cGMP-dependent vasodilatation in the vessels of lesser circulation in endothelial dysfunction].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova20050201

Title: Monocrotaline, an alternative to retrorsine-based hepatocyte transplantation in rodents.

Journal: Cell transplantation20050101

Title: PKC translocation and ERK1/2 activation in compensated right ventricular hypertrophy secondary to chronic emphysema.

Journal: BMC physiology20050101

Title: [Effect of chronic administration of aminoguanidine on vascular reactivity of the greater circulation in rats with monocrotaline-induced pulmonary hypertension].

Journal: Izvestiia Akademii nauk. Seriia biologicheskaia20050101

Title: Attenuated noradrenaline-induced contraction of pulmonary arteries from rats treated with monocrotaline: role of rho kinase.

Journal: Journal of vascular research20050101

Title: Influence of hypoxia on the domiciliation of mesenchymal stem cells after infusion into rats: possibilities of targeting pulmonary artery remodeling via cells therapies?

Journal: Respiratory research20050101

Title: Inhaled tolafentrine reverses pulmonary vascular remodeling via inhibition of smooth muscle cell migration.

Journal: Respiratory research20050101

Title: If you've got it, flaunt it: ingested alkaloids affect corematal display behavior in the salt marsh moth, Estigmene acrea.

Journal: Journal of insect science (Online)20050101

Title: Chloride channels and alpha1-adrenoceptor-mediated pulmonary artery smooth muscle contraction: effect of pulmonary hypertension.

Journal: European journal of pharmacology20041215

Title: DNA cross-linking by dehydromonocrotaline lacks apparent base sequence preference.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20041201

Title: Endogenous production of ghrelin and beneficial effects of its exogenous administration in monocrotaline-induced pulmonary hypertension.

Journal: American journal of physiology. Heart and circulatory physiology20041201

Title: C-type natriuretic peptide ameliorates monocrotaline-induced pulmonary hypertension in rats.

Journal: American journal of respiratory and critical care medicine20041201

Title: Gene transfer of hepatocyte growth factor with prostacyclin synthase in severe pulmonary hypertension of rats.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery20041201

Title: Specific inhibition of p38 mitogen-activated protein kinase with FR167653 attenuates vascular proliferation in monocrotaline-induced pulmonary hypertension in rats.

Journal: The Journal of thoracic and cardiovascular surgery20041201

Title: Repeated gene transfer of naked prostacyclin synthase plasmid into skeletal muscles attenuates monocrotaline-induced pulmonary hypertension and prolongs survival in rats.

Journal: Human gene therapy20041201

Title: Hepatocyte growth factor suppresses vascular medial hyperplasia and matrix accumulation in advanced pulmonary hypertension of rats.

Journal: Circulation20041102

Title: Comparison of hepatic in vitro metabolism of the pyrrolizidine alkaloid senecionine in sheep and cattle.

Journal: American journal of veterinary research20041101

Title: YM598, an orally active ET(A) receptor antagonist, ameliorates the progression of cardiopulmonary changes and both-side heart failure in rats with cor pulmonale and myocardial infarction.

Journal: Journal of cardiovascular pharmacology20041101

Title: Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis.

Journal: Circulation research20041015

Title: Disruption of endothelial-cell caveolin-1alpha/raft scaffolding during development of monocrotaline-induced pulmonary hypertension.

Journal: Circulation20040914

Title: The orally active nonpeptide selective endothelin ETA receptor antagonist YM598 prevents and reverses the development of pulmonary hypertension in monocrotaline-treated rats.

Journal: European journal of pharmacology20040802

Title: Role of endothelin ETB receptor in the pathogenesis of monocrotaline-induced pulmonary hypertension in rats.

Journal: European journal of pharmacology20040802

Title: Roles of endothelin ETA and ETB receptors in the pathogenesis of monocrotaline-induced pulmonary hypertension.

Journal: Journal of cardiovascular pharmacology20040801

Title: [Effect of chronic administration of aminoguanidine on the reactivity of pulmonary vessels in rats with monocrotaline-induced pulmonary hypertension].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova20040701

Title: Emission-particle-induced ventilatory abnormalities in a rat model of pulmonary hypertension.

Journal: Environmental health perspectives20040601

Title: Effect of 5-lipoxygenase on the development of pulmonary hypertension in rats.

Journal: American journal of physiology. Heart and circulatory physiology20040501

Title: [Effect of elastase inhibitor on pulmonary hypertension induced by monocrotaline].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics20040501

Title: Antioxidant and oxidative stress changes in experimental cor pulmonale.

Journal: Molecular and cellular biochemistry20040501

Title: Antiremodeling effects of iloprost and the dual-selective phosphodiesterase 3/4 inhibitor tolafentrine in chronic experimental pulmonary hypertension.

Journal: Circulation research20040430

Title: Longitudinal transcriptional analysis of developing neointimal vascular occlusion and pulmonary hypertension in rats.

Journal: Physiological genomics20040413

Title: Cell therapy for pulmonary hypertension: what is the true potential of endothelial progenitor cells?

Journal: Circulation20040330

Title: Contractile reserve but not tension is reduced in monocrotaline-induced right ventricular hypertrophy.

Journal: American journal of physiology. Heart and circulatory physiology20040301

Title: Nitric oxide formation and plasma L-arginine levels in pulmonary hypertensive rats.

Journal: Respiratory medicine20040301

Title: Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats.

Journal: Circulation research20040220

Title: Right ventricle-sparing heart transplantation effective against iatrogenic pulmonary hypertension.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation20040201

Title: Downregulation of Kv4.2 and Kv4.3 channel gene expression in right ventricular hypertrophy induced by monocrotaline in rat.

Journal: Acta pharmacologica Sinica20040201

Title: Acquired and partially de novo synthesized pyrrolizidine alkaloids in two polyphagous arctiids and the alkaloid profiles of their larval food-plants.

Journal: Journal of chemical ecology20040201

Title: Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats.

Journal: American journal of respiratory and critical care medicine20040101

Title: Beneficial effects of GH/IGF-1 on skeletal muscle atrophy and function in experimental heart failure.

Journal: American journal of physiology. Cell physiology20040101

Title: A combination of oral sildenafil and beraprost ameliorates pulmonary hypertension in rats.

Journal: American journal of respiratory and critical care medicine20040101

Title: Effect of nolomirole on monocrotaline-induced heart failure.

Journal: Pharmacological research20040101

Title: Modes of cell death in rat liver after monocrotaline exposure.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20040101

Title: Effect of endothelin antagonism on contractility, intracellular calcium regulation and calcium regulatory protein expression in right ventricular hypertrophy of the rat.

Journal: Basic & clinical pharmacology & toxicology20040101

Title: Chronic hypoxia- and monocrotaline-induced elevation of hypoxia-inducible factor-1 alpha levels and pulmonary hypertension.

Journal: Journal of biomedical science20040101

Title: Comparison of strength properties of normotensive and hypertensive rat pulmonary arteries.

Journal: Biomedical sciences instrumentation20040101

Title: Transplantation of endothelial progenitor cells into the lung to alleviate pulmonary hypertension in dogs.

Journal: Tissue engineering20040101

Title: JTV-506, a new K(ATP) channel opener, relaxes pulmonary artery isolated from monocrotaline-treated pulmonary hypertensive rats.

Journal: Journal of anesthesia20040101

Title: Alpha 1-adrenoceptor subtypes mediating noradrenaline-induced contraction of pulmonary artery from pulmonary hypertensive rats.

Journal: European journal of pharmacology20031215

Title: Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine alkaloid riddelliine.

Journal: Toxicology letters20031210

Title: Activation of the right ventricular endothelin (ET) system in the monocrotaline model of pulmonary hypertension: response to chronic ETA receptor blockade.

Journal: Clinical science (London, England : 1979)20031201

Title: Serotonin receptor antagonist inhibits monocrotaline-induced pulmonary hypertension and prolongs survival in rats.

Journal: Cardiovascular research20031201

Title: [Involvement of tetrahydrobiopterin in local change of endothelium-dependent vasorelaxation in pulmonary hypertension].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova20031201

Title: Basement membrane and matrix metalloproteinases in monocrotaline-induced liver injury.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20031101

Title: Augmented pulmonary vascular and venous constrictions to N(G)-nitro-L-arginine methyl ester in rats with monocrotaline-induced pulmonary hypertension.

Journal: Pharmacology20031101

Title: Rhythmical contractions in pulmonary arteries of monocrotaline-induced pulmonary hypertensive rats.

Journal: Pflugers Archiv : European journal of physiology20031101

Title: Experience influences gustatory responsiveness to pyrrolizidine alkaloids in the polyphagous caterpillar, Estigmene acrea.

Journal: Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology20031101

Title: Repeated inhalation of adrenomedullin ameliorates pulmonary hypertension and survival in monocrotaline rats.

Journal: American journal of physiology. Heart and circulatory physiology20031101

Title: Are insect-synthesized retronecine esters (creatonotines) the precursors of the male courtship pheromone in the arctiid moth Estigmene acrea?

Journal: Journal of chemical ecology20031101

Title: Decreased hepatic nitric oxide production contributes to the development of rat sinusoidal obstruction syndrome.

Journal: Hepatology (Baltimore, Md.)20031001

Title: Estrogen and enalapril attenuate the development of right ventricular hypertrophy induced by monocrotaline in ovariectomized rats.

Journal: Journal of Korean medical science20031001

Title: Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells.

Journal: Circulation20030930

Title: Sinusoidal obstruction syndrome (veno-occlusive disease) in the rat is prevented by matrix metalloproteinase inhibition.

Journal: Gastroenterology20030901

Title: Identification of DNA adducts derived from riddelliine, a carcinogenic pyrrolizidine alkaloid.

Journal: Chemical research in toxicology20030901

Title: Liver inflammation during monocrotaline hepatotoxicity.

Journal: Toxicology20030828

Title: Hybrid cell-gene therapy for pulmonary hypertension based on phagocytosing action of endothelial progenitor cells.

Journal: Circulation20030819

Title: Mechanical load-dependent regulation of gene expression in monocrotaline-induced right ventricular hypertrophy in the rat.

Journal: Circulation research20030808

Title: Comparative scoring of micronucleated reticulocytes in rat peripheral blood by flow cytometry and microscopy.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20030801

Title: The coagulation system contributes to synergistic liver injury from exposure to monocrotaline and bacterial lipopolysaccharide.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20030801

Title: DA-8159, a potent cGMP phosphodiesterase inhibitor, attenuates monocrotaline-induced pulmonary hypertension in rats.

Journal: Archives of pharmacal research20030801

Title: Endothelial cell injury and coagulation system activation during synergistic hepatotoxicity from monocrotaline and bacterial lipopolysaccharide coexposure.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20030701

Title: Taste receptors for pyrrolizidine alkaloids in a monophagous caterpillar.

Journal: Journal of chemical ecology20030701

Title: Progressive development of pulmonary hypertension leading to right ventricular hypertrophy assessed by echocardiography in rats.

Journal: Experimental animals20030701

Title: Inhibition of matrix metalloproteinases by lung TIMP-1 gene transfer limits monocrotaline-induced pulmonary vascular remodeling in rats.

Journal: Human gene therapy20030610

Title: Embolization by sinusoidal lining cells obstructs the microcirculation in rat sinusoidal obstruction syndrome.

Journal: American journal of physiology. Gastrointestinal and liver physiology20030601

Title: Pyrrolizidine alkaloids as oviposition stimulants for the cinnabar moth, Tyria jacobaeae.

Journal: Journal of chemical ecology20030601

Title: Protective role of angiopoietin-1 in experimental pulmonary hypertension.

Journal: Circulation research20030516

Title: Granulocyte colony-stimulating factor enhances alpha-naphthylthiourea-induced pulmonary hypertension.

Journal: Journal of applied physiology (Bethesda, Md. : 1985)20030501

Title: Effect of a surgical aortocaval fistula on monocrotaline-induced pulmonary hypertension.

Journal: Critical care medicine20030401

Title: Tachykinin dysfunction attenuates monocrotaline-induced pulmonary hypertension.

Journal: Toxicology and applied pharmacology20030315

Title: Effects of monocrotaline pyrrole and thrombin on pulmonary endothelial cell junction and matrix adhesion proteins.

Journal: Toxicology20030303

Title: Role of neutrophils in the synergistic liver injury from monocrotaline and bacterial lipopolysaccharide exposure.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20030301

Title: Cardiac beta-adrenoceptor changes in monocrotaline-treated rats: differences between membrane preparations from whole ventricles and isolated ventricular cardiomyocytes.

Journal: Journal of cardiovascular pharmacology20030301

Title: Skeletal muscle abnormalities in rats with experimentally induced heart hypertrophy and failure.

Journal: Basic research in cardiology20030301

Title: Final height outcome and value of height prediction in boys with constitutional delay in growth and adolescence treated with intramuscular testosterone 125 mg per month for 3 months.

Journal: Clinical endocrinology20030301

Title: The role of Kupffer cells and TNF-alpha in monocrotaline and bacterial lipopolysaccharide-induced liver injury.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20030101

Title: Cytostatic properties of some angiotensin I converting enzyme inhibitors and of angiotensin II type I receptor antagonists.

Journal: Current pharmaceutical design20030101

Title: The activation pattern of the antioxidant enzymes in the right ventricle of rat in response to pressure overload is of heart failure type.

Journal: Heart disease (Hagerstown, Md.)20030101

Title: Gender differences in pulmonary arterial reactivity to dilatory agonists in pulmonary hypertension.

Journal: The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia20030101

Title: DA-8159, a new PDE5 inhibitor, attenuates the development of compensatory right ventricular hypertrophy in a rat model of pulmonary hypertension.

Journal: The Journal of international medical research20030101

Title: Dietary alkaloids and the development of androconial organs in Estigmene acrea.

Journal: Journal of insect science (Online)20030101

Title: Pulmonary effects of ultrafine and fine ammonium salts aerosols in healthy and monocrotaline-treated rats following short-term exposure.

Journal: Inhalation toxicology20021201

Title: Pyrrolizidine alkaloid clivorine inhibits human normal liver L-02 cells growth and activates p38 mitogen-activated protein kinase in L-02 cells.

Journal: Toxicon : official journal of the International Society on Toxinology20021201

Title: Ventricular hypertrophy plus neurohumoral activation is necessary to alter the cardiac beta-adrenoceptor system in experimental heart failure.

Journal: Circulation research20021129

Title: Simvastatin attenuates smooth muscle neointimal proliferation and pulmonary hypertension in rats.

Journal: American journal of respiratory and critical care medicine20021115

Title: Dexfenfluramine protects against pulmonary hypertension in rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985)20021101

Title: Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary hypertension in rats.

Journal: American journal of physiology. Heart and circulatory physiology20021101

Title: Acute and chronic effects of T-1032, a novel selective phosphodiesterase type 5 inhibitor, on monocrotaline-induced pulmonary hypertension in rats.

Journal: Biological & pharmaceutical bulletin20021101

Title: Cardiac and thermoregulatory effects of instilled particulate matter-associated transition metals in healthy and cardiopulmonary-compromised rats.

Journal: Journal of toxicology and environmental health. Part A20021025

Title: L-Carnitine: a potential treatment for blocking apoptosis and preventing skeletal muscle myopathy in heart failure.

Journal: American journal of physiology. Cell physiology20020901

Title: Calibrated histochemistry applied to oxygen supply and demand in hypertrophied rat myocardium.

Journal: Microscopy research and technique20020901

Title: Pyrrolizidine alkaloids from Senecio jacobaea affect fungal growth.

Journal: Journal of chemical ecology20020901

Title: Cardiac modulations of ANG II receptor expression in rats with hypoxic pulmonary hypertension.

Journal: American journal of physiology. Heart and circulatory physiology20020801

Title: Effect of thalidomide on the skeletal muscle in experimental heart failure.

Journal: European journal of heart failure20020801

Title: Heme oxygenase-1 reduces murine monocrotaline-induced pulmonary inflammatory responses and resultant right ventricular overload.

Journal: Antioxidants & redox signaling20020801

Title: Reduction of monocrotaline-induced hepatic injury by deleted variant of hepatocyte growth factor (dHGF) in rats.

Journal: Liver20020801

Title: [The effect and mechanism of felodipine on monocrotaline induced pulmonary hypertension in rats].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases20020801

Title: The temporal relationship between bacterial lipopolysaccharide and monocrotaline exposures influences toxicity: shift in response from hepatotoxicity to nitric oxide-dependent lethality.

Journal: Journal of toxicology and environmental health. Part A20020726

Title: Serial noninvasive assessment of progressive pulmonary hypertension in a rat model.

Journal: American journal of physiology. Heart and circulatory physiology20020701

Title: Effects of diesel exhaust enriched concentrated PM2.5 in ozone preexposed or monocrotaline-treated rats.

Journal: Inhalation toxicology20020701

Title: Dietary fish oil protects against lung and liver inflammation and fibrosis in monocrotaline treated rats.

Journal: Toxicology20020614

Title: Suppressive effect of pulmonary hypertension and leukocyte activation by inhaled prostaglandin E1 in rats with monocrotaline-induced pulmonary hypertension.

Journal: Experimental lung research20020601

Title: Attenuation of negatively regulated ANP secretion by calcium in hypertrophied atria.

Journal: Regulatory peptides20020530

Title: Anticoagulants prevent monocrotaline-induced hepatic parenchymal cell injury but not endothelial cell injury in the rat.

Journal: Toxicology and applied pharmacology20020501

Title: Stage-dependent activation of cell cycle and apoptosis mechanisms in the right ventricle by pressure overload.

Journal: Biochimica et biophysica acta20020424

Title: The effects of vasoactive intestinal peptide on monocrotaline induced pulmonary hypertensive rabbits following cardiopulmonary bypass: a comparative study with isoproteronol and nitroglycerine.

Journal: Cardiovascular surgery (London, England)20020401

Title: Temporal modulation of pyrrolizidine alkaloid intake and genetic variation in performance of Utetheisa ornatrix caterpillars.

Journal: Journal of chemical ecology20020401

Title: Therapeutic effects of DCDDP, a calcium channel blocker, on chronic pulmonary hypertension in rat.

Journal: Journal of applied physiology (Bethesda, Md. : 1985)20020301

Title: Defective intracellular calcium handling in monocrotaline-induced right ventricular hypertrophy: protective effect of long-term endothelin-A receptor blockade with 2-benzo[1,3]dioxol-5-yl-3-benzyl-4-(4-methoxy-phenyl-)- 4-oxobut-2-enoate-sodium (PD 155080).

Journal: The Journal of pharmacology and experimental therapeutics20020201

Title: Endothelial cell injury and fibrin deposition in rat liver after monocrotaline exposure.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20020201

Title: Changes in alpha(1)-adrenergic vascular reactivity in monocrotaline-treated rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20020201

Title: Changes of sequestered leukocytes and platelets by inhalation prostaglandin E(1) in the pulmonary microvasculature of rats with monocrotaline-induced pulmonary hypertension.

Journal: Journal of vascular research20020101

Title: Effects of monocrotaline on endothelial nitric oxide synthase expression and sulfhydryl levels in rat lungs.

Journal: Heart disease (Hagerstown, Md.)20020101

Title: Myocardial force development and structural changes associated with monocrotaline induced cardiac hypertrophy and heart failure.

Journal: Journal of muscle research and cell motility20020101

Title: Attenuation of inhibitory effect of CNP on the secretion of ANP from hypertrophied atria.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20011101

Title: Gelatinase expression in pulmonary arteries during experimental pulmonary hypertension.

Journal: The European respiratory journal20011101

Title: Gemtuzumab Ozogamicin (Mylotarg) and hepatic veno-occlusive disease: take two acetaminophen, and..

Journal: Bone marrow transplantation20011101

Title: Cell-based gene transfer of vascular endothelial growth factor attenuates monocrotaline-induced pulmonary hypertension.

Journal: Circulation20011030

Title: Accentuation of ANP secretion to endothelin-1 in hypertrophied atria.

Journal: Regulatory peptides20011015

Title: Decrease in the Ca2+-activated K+ current of pulmonary arterial smooth muscle in pulmonary hypertension rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20010901

Title: Time- and subunit-dependent differential mRNA expression of L-type Ca2+ channel during progression of right ventricular hypertrophy.

Journal: Japanese heart journal20010901

Title: Angiotensin-converting enzyme inhibitor preserves p21 and endothelial nitric oxide synthase expression in monocrotaline-induced pulmonary arterial hypertension in rats.

Journal: Circulation20010821

Title: Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles.

Journal: Toxicology and applied pharmacology20010815

Title: Attenuation of compensatory right ventricular hypertrophy and heart failure following monocrotaline-induced pulmonary vascular injury by the Na+-H+ exchange inhibitor cariporide.

Journal: The Journal of pharmacology and experimental therapeutics20010801

Title: Restoration of calcium handling properties of adult cardiac myocytes from hypertrophied hearts.

Journal: Cell calcium20010701

Title: Lack of protective action of cysteine against the fetotoxic effect of monocrotaline.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20010701

Title: Contribution of chloride channel activation to the elevated muscular tone of the pulmonary artery in monocrotaline-induced pulmonary hypertensive rats.

Journal: Japanese journal of pharmacology20010701

Title: [Monocrotaline-induced pulmonary hypertension in animals].

Journal: Nihon rinsho. Japanese journal of clinical medicine20010601

Title: [Drug induced pulmonary hypertension].

Journal: Nihon rinsho. Japanese journal of clinical medicine20010601

Title: Beneficial effects on skeletal muscle of the angiotensin II type 1 receptor blocker irbesartan in experimental heart failure.

Journal: Circulation20010501

Title: All-trans retinoic acid in pulmonary vascular structural remodeling in rats with pulmonary hypertension induced by monocrotaline.

Journal: Chinese medical journal20010501

Title: Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity.

Journal: Toxicology letters20010331

Title: Reactive oxygen species and substance P in monocrotaline-induced pulmonary hypertension.

Journal: Toxicology and applied pharmacology20010315

Title: Enhanced gene expression of renin-angiotensin system, TGF-beta1, endothelin-1 and nitric oxide synthase in right-ventricular hypertrophy.

Journal: Pharmacological research20010301

Title: Apoptosis and changes in contractile protein pattern in the skeletal muscle in heart failure.

Journal: Acta physiologica Scandinavica20010301

Title: 5-HT1B receptor augmented 5-HT vasoconstrictor response of pulmonary artery in monocrotaline-induced pulmonary hypertensive rats.

Journal: Acta pharmacologica Sinica20010301

Title: Hemodynamic unloading leads to regression of pulmonary vascular disease in rats.

Journal: The Journal of thoracic and cardiovascular surgery20010201

Title: 40-O-(2-hydroxyethyl)-rapamycin attenuates pulmonary arterial hypertension and neointimal formation in rats.

Journal: American journal of respiratory and critical care medicine20010201

Title: Effectiveness of a nonselective ET(A/B) and a selective ET(A) antagonist in rats with monocrotaline-induced pulmonary hypertension.

Journal: Circulation20010116

Title: Development of a (32)P-postlabeling/HPLC method for detection of dehydroretronecine-derived DNA adducts in vivo and in vitro.

Journal: Chemical research in toxicology20010101

Title: Metabolic activation of the tumorigenic pyrrolizidine alkaloid, riddelliine, leading to DNA adduct formation in vivo.

Journal: Chemical research in toxicology20010101

Title: Vascular remodeling in experimentally induced subacute canine pulmonary hypertension.

Journal: Experimental lung research20010101

Title: Micronucleus formation in human lymphocytes and in the metabolically competent human hepatoma cell line Hep-G2: results with 15 naturally occurring substances.

Journal: Anticancer research20010101

Title: [Monocrotaline induce pulmonary hypertension in animal models].

Journal: Pneumologia (Bucharest, Romania)20010101

Title: Role of endothelin-1 in lung disease.

Journal: Respiratory research20010101

Title: Genomic approaches to research in pulmonary hypertension.

Journal: Respiratory research20010101

Title: Molecular mechanisms of cardiac hypertrophy induced by toxicants.

Journal: Cardiovascular toxicology20010101

Title: Polyamine regulatory processes and oxidative stress in monocrotaline-treated pulmonary artery endothelial cells.

Journal: Cell biology international19971201

Title: Oxidative stress mediates monocrotaline-induced alterations in tenascin expression in pulmonary artery endothelial cells.

Journal: The international journal of biochemistry & cell biology19970501

Title: Effect of losartan on right ventricular hypertrophy and cardiac angiotensin I-converting enzyme activity in pulmonary hypertensive rats.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993)19960101

Title: Pinacidil-induced relaxation in pulmonary arteries isolated from pulmonary hypertensive and normotensive rats and pre-contracted with different spasmogens.

Journal: Pulmonary pharmacology19941201

Title: COR pulmonale is caused by monocrotaline and dehydromonocrotaline, but not by glutathione or cysteine conjugates of dihydropyrrolizine.

Journal: Toxicology and applied pharmacology19930101

Title: Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.

Journal: Journal of natural products19910101

Title: Gomez-Arroyo JG, et al. The monocrotaline model of pulmonary hypertension in perspective. Am J Physiol Lung Cell Mol Physiol. 2012 Feb 15;302(4):L363-9.

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Title: Wilson DW, et, al. Mechanisms and pathology of monocrotaline pulmonary toxicity. Crit Rev Toxicol. 1992;22(5-6):307-25.

Title: Nogueira-Ferreira R, et al. Exploring the monocrotaline animal model for the study of pulmonary arterial hypertension: A network approach. Pulm Pharmacol Ther. 2015 Dec;35:8-16.

Title: Rafikova O,et al. Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed RatLung. PLoS One. 2016 Mar 3;11(3):e0150480.

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