Title: Lysophosphatidic acid alters the expression profiles of angiogenic factors, cytokines, and chemokines in mouse liver sinusoidal endothelial cells.
Journal: PloS one20150101
Title: Effects of lysophosphatidic acid on calpain-mediated proteolysis of focal adhesion kinase in human prostate cancer cells.
Journal: The Prostate20121101
Title: Discovery of highly selective and orally active lysophosphatidic acid receptor-1 antagonists with potent activity on human lung fibroblasts.
Journal: Journal of medicinal chemistry20120913
Title: Effect of inhibition of the lysophosphatidic acid receptor 1 on metastasis and metastatic dormancy in breast cancer.
Journal: Journal of the National Cancer Institute20120905
Title: Selective non-lipid modulator of LPA5 activity in human platelets.
Journal: Bioorganic & medicinal chemistry letters20120815
Title: Synthesis and biological evaluation of optically active Ki16425.
Journal: Bioorganic & medicinal chemistry letters20120701
Title: Gintonin, newly identified compounds from ginseng, is novel lysophosphatidic acids-protein complexes and activates G protein-coupled lysophosphatidic acid receptors with high affinity.
Journal: Molecules and cells20120227
Title: Gintonin, a ginseng-derived lysophosphatidic acid receptor ligand, attenuates Alzheimer's disease-related neuropathies: involvement of non-amyloidogenic processing.
Journal: Journal of Alzheimer's disease : JAD20120101
Title: Lysophosphatidic acid induces erythropoiesis through activating lysophosphatidic acid receptor 3.
Journal: Stem cells (Dayton, Ohio)20111101
Title: Lysophosphatidic acid receptor 1 modulates lipopolysaccharide-induced inflammation in alveolar epithelial cells and murine lungs.
Journal: American journal of physiology. Lung cellular and molecular physiology20111001
Title: TNF-α potentiates lysophosphatidic acid-induced COX-2 expression via PKD in human colonic myofibroblasts.
Journal: American journal of physiology. Gastrointestinal and liver physiology20110401
Title: Stimulatory actions of lysophosphatidic acid on mouse ATDC5 chondroprogenitor cells.
Journal: Journal of bone and mineral metabolism20101101
Title: Diversity of lysophosphatidic acid receptor-mediated intracellular calcium signaling in early cortical neurogenesis.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20100526
Title: Synthesis, in vitro structure-activity relationship, and in vivo studies of 2-arylthiazolidine-4-carboxylic acid amides as anticancer agents.
Journal: Bioorganic & medicinal chemistry20100115
Title: Regulation of cerebromicrovascular permeability by lysophosphatidic acid.
Journal: Microcirculation (New York, N.Y. : 1994)20100101
Title: Lysophosphatidic acid stimulates prostaglandin E2 production in cultured stromal endometrial cells through LPA1 receptor.
Journal: Experimental biology and medicine (Maywood, N.J.)20090801
Title: Lysophosphatidic Acid signals through specific lysophosphatidic Acid receptor subtypes to control key regenerative responses of human gingival and periodontal ligament fibroblasts.
Journal: Journal of periodontology20090801
Title: Evidence for lysophosphatidic acid 1 receptor signaling in the early phase of neuropathic pain mechanisms in experiments using Ki-16425, a lysophosphatidic acid 1 receptor antagonist.
Journal: Journal of neurochemistry20090401
Title: LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites.
Journal: Carcinogenesis20090301
Title: Lysophosphatic acid modulates prostaglandin secretion in the bovine uterus.
Journal: Reproduction (Cambridge, England)20090101
Title: Lysophosphatidic acid stimulates cell growth by different mechanisms in SKOV-3 and Caov-3 ovarian cancer cells: distinct roles for Gi- and Rho-dependent pathways.
Journal: Pharmacology20090101
Title: Stimulatory role of lysophosphatidic acid in cyclooxygenase-2 induction by synovial fluid of patients with rheumatoid arthritis in fibroblast-like synovial cells.
Journal: Journal of immunology (Baltimore, Md. : 1950)20081001
Title: Lysophosphatidylserine stimulates chemotactic migration in U87 human glioma cells.
Journal: Biochemical and biophysical research communications20080912
Title: Lysophosphatidic acid stimulates the proliferation and motility of malignant pleural mesothelioma cells through lysophosphatidic acid receptors, LPA1 and LPA2.
Journal: Cancer science20080801
Title: Lysophosphatidylglycerol stimulates chemotactic migration in human natural killer cells.
Journal: Biochemical and biophysical research communications20080718
Title: Lysophosphatidic acid protects cancer cells from histone deacetylase (HDAC) inhibitor-induced apoptosis through activation of HDAC.
Journal: The Journal of biological chemistry20080613
Title: Identification of non-lipid LPA3 antagonists by virtual screening.
Journal: Bioorganic & medicinal chemistry20080601
Title: Dioleoyl phosphatidic acid induces morphological changes through an endogenous LPA receptor in C6 glioma cells.
Journal: Archives of pharmacal research20080501
Title: Bacteria induce CTGF and CYR61 expression in epithelial cells in a lysophosphatidic acid receptor-dependent manner.
Journal: International journal of medical microbiology : IJMM20080401
Title: Lysophosphatidic acid-stimulated interleukin-6 and -8 synthesis through LPA1 receptors on human osteoblasts.
Journal: Archives of oral biology20080301
Title: Lysophosphatidylserine induces calcium signaling through Ki16425/VPC32183-sensitive GPCR in bone marrow-derived mast cells and in C6 glioma and colon cancer cells.
Journal: Archives of pharmacal research20080301
Title: Lysophosphatidic acid regulates blood glucose by stimulating myotube and adipocyte glucose uptake.
Journal: Journal of molecular medicine (Berlin, Germany)20080201
Title: LPA1 receptor activation promotes renal interstitial fibrosis.
Journal: Journal of the American Society of Nephrology : JASN20071201
Title: Lysophosphatidylglycerol stimulates chemotactic migration and tube formation in human umbilical vein endothelial cells.
Journal: Biochemical and biophysical research communications20071123
Title: The orphan GPCR GPR87 was deorphanized and shown to be a lysophosphatidic acid receptor.
Journal: Biochemical and biophysical research communications20071123
Title: Activatory properties of lysophosphatidic acid on human THP-1 cells.
Journal: Inflammation20071001
Title: Synthesis and evaluation of isoxazole derivatives as lysophosphatidic acid (LPA) antagonists.
Journal: Bioorganic & medicinal chemistry letters20070701
Title: Dioleoyl phosphatidic acid increases intracellular Ca2+ through endogenous LPA receptors in C6 glioma and L2071 fibroblasts.
Journal: Prostaglandins & other lipid mediators20070601
Title: LPA2 (EDG4) mediates Rho-dependent chemotaxis with lower efficacy than LPA1 (EDG2) in breast carcinoma cells.
Journal: American journal of physiology. Cell physiology20070501
Title: Lysophosphatidic acid stimulates neuronal differentiation of cortical neuroblasts through the LPA1-G(i/o) pathway.
Journal: Neurochemistry international20070101
Title: Lysophosphatidic acid as a mediator for proinflammatory agonists in a human corneal epithelial cell line.
Journal: American journal of physiology. Cell physiology20061101
Title: Protean agonism of the lysophosphatidic acid receptor-1 with Ki16425 reduces nerve growth factor-induced neurite outgrowth in pheochromocytoma 12 cells.
Journal: Journal of neurochemistry20060901
Title: Integrin signalling regulates the nuclear localization and function of the lysophosphatidic acid receptor-1 (LPA1) in mammalian cells.
Journal: The Biochemical journal20060815
Title: Lysophosphatidic acid induces chemotaxis in MC3T3-E1 osteoblastic cells.
Journal: Bone20060701
Title: Lysophosphatidic acid cooperates with 1alpha,25(OH)2D3 in stimulating human MG63 osteoblast maturation.
Journal: Prostaglandins & other lipid mediators20060701
Title: The basic secretagogue compound 48/80 activates G proteins indirectly via stimulation of phospholipase D-lysophosphatidic acid receptor axis and 5-HT1A receptors in rat brain sections.
Journal: British journal of pharmacology20060301
Title: Lysophosphatidic acid is a major regulator of growth-regulated oncogene alpha in ovarian cancer.
Journal: Cancer research20060301
Title: Lysophosphatidic acid (LPA)-induced vascular endothelial growth factor (VEGF) by mesothelial cells and quantification of host-derived VEGF in malignant ascites.
Journal: The Journal of surgical research20060101
Title: Activatory properties of lysophosphatidic acid on human THP-1 cells.
Journal: Inflammation20051201
Title: Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin.
Journal: Journal of medicinal chemistry20050728
Title: Identification of autotaxin as a neurite retraction-inducing factor of PC12 cells in cerebrospinal fluid and its possible sources.
Journal: Journal of neurochemistry20050201
Title: Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1.
Journal: The Journal of biological chemistry20040423
Title: Lysophosphatidic acid (LPA) in malignant ascites stimulates motility of human pancreatic cancer cells through LPA1.
Journal: The Journal of biological chemistry20040220
Title: Ki16425, a subtype-selective antagonist for EDG-family lysophosphatidic acid receptors.
Journal: Molecular pharmacology20031001
