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302-91-0,MFCD00003670
Catalog No.:AA00C2FJ

302-91-0 | ALLOTETRAHYDROCORTISOL

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5mg
98%
2 weeks  
$1,756.00   $1,229.00
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  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C2FJ
Chemical Name:
ALLOTETRAHYDROCORTISOL
CAS Number:
302-91-0
Molecular Formula:
C21H34O5
Molecular Weight:
366.4917
MDL Number:
MFCD00003670
SMILES:
OCC(=O)[C@@]1(O)CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CC[C@@H]2[C@]1(C)CC[C@H](C2)O
NSC Number:
86469
Properties
Computed Properties
 
Complexity:
593  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
2  
XLogP3:
2.5  

Literature

Title: Role of 11βHSD type 2 enzyme activity in essential hypertension and children with chronic kidney disease (CKD).

Journal: The Journal of clinical endocrinology and metabolism 20121001

Title: 11β-hydroxysteroid dehydrogenase type 2 polymorphisms and activity in a Chilean essential hypertensive and normotensive cohort.

Journal: American journal of hypertension 20120501

Title: HPLC method for determination of fluorescence derivatives of cortisol, cortisone and their tetrahydro- and allo-tetrahydro-metabolites in biological fluids.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201

Title: Enduring effects of severe developmental adversity, including nutritional deprivation, on cortisol metabolism in aging Holocaust survivors.

Journal: Journal of psychiatric research 20090601

Title: A randomized placebo-controlled study on the effects of pioglitazone on cortisol metabolism in polycystic ovary syndrome.

Journal: Fertility and sterility 20090301

Title: Cortisol metabolism in depressed patients and healthy controls.

Journal: Neuroendocrinology 20090101

Title: Simultaneous determination of tetrahydrocortisol, allotetrahydrocortisol and tetrahydrocortisone in human urine by liquid chromatography-electrospray ionization tandem mass spectrometry.

Journal: Steroids 20080801

Title: Urinary cortisol to cortisone metabolites ratio in prednisone-treated and spontaneously hypertensive patients.

Journal: Journal of hypertension 20080301

Title: Endogenous corticosteroid biosynthesis in subjects after bilateral adrenalectomy.

Journal: Clinical endocrinology 20070501

Title: Direct determination of the ratio of tetrahydrocortisol+allo-tetrahydrocortisol to tetrahydrocortisone in urine by LC-MS-MS.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060118

Title: Urinary steroid excretion rates in acromegaly.

Journal: Hormone research 20050101

Title: Hydrolysis of conjugated steroids by the combined use of beta-glucuronidase preparations from helix pomatia and ampullaria: determination of urinary cortisol and its metabolites.

Journal: Steroids 20011101

Title: Interference by danazol with the Porter-Silber method for determination of urinary 17-hydroxycorticosteroids.

Journal: Annals of clinical biochemistry 20010501

Title: BUSH IE, et al. The excretion of allo tetrahydrocortisol in human urine. Biochem J. 1957 Dec;67(4):689-700.

Title: Kosicka K, et al. Detailed analysis of cortisol, cortisone and their tetrahydro- and allo-tetrahydrometabolites in human urine by LC-MS/MS. J Pharm Biomed Anal. 2017 Jun 5;140:174-181.

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Tags:302-91-0 Molecular Formula|302-91-0 MDL|302-91-0 SMILES|302-91-0 ALLOTETRAHYDROCORTISOL