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2393-58-0,MFCD00271402
Catalog No.:AA00C2N2

2393-58-0 | (3a,5b,6b,7a)-3,6,7-trihydroxy-Cholan-24-oic acid

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1mg
≥95%
in stock  
$168.00   $117.00
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5mg
≥95%
in stock  
$578.00   $404.00
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10mg
≥95%
in stock  
$1,072.00   $750.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C2N2
Chemical Name:
(3a,5b,6b,7a)-3,6,7-trihydroxy-Cholan-24-oic acid
CAS Number:
2393-58-0
Molecular Formula:
C24H40O5
Molecular Weight:
408.5714
MDL Number:
MFCD00271402
SMILES:
O[C@@H]1CC[C@]2([C@@H](C1)[C@H](O)[C@H]([C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2[C@@H](CCC(=O)O)C)C)O)C
Properties
Computed Properties
 
Complexity:
637  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
11  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
4  
XLogP3:
3.9  

Literature

Title: Characterization of urinary bile acids in a pediatric BRIC-1 patient: effect of rifampicin treatment.

Journal: Clinica chimica acta; international journal of clinical chemistry 20120816

Title: Improved analysis of bile acids in tissues and intestinal contents of rats using LC/ESI-MS.

Journal: Journal of lipid research 20090101

Title: Increased cholesterol 7alpha-hydroxylase expression and size of the bile acid pool in the lactating rat.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20080401

Title: Perinatal bile acid metabolism: bile acid analysis of meconium of preterm and full-term infants.

Journal: Journal of gastroenterology 20071101

Title: Ontogenic development-associated changes in the expression of genes involved in rat bile acid homeostasis.

Journal: Journal of lipid research 20070601

Title: Two loci on chromosome 9 control bile acid composition: evidence that a strong candidate gene, Cyp8b1, is not the culprit.

Journal: Journal of lipid research 20060901

Title: Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides.

Journal: Journal of hepatology 20060401

Title: Gene structure of pig sterol 12alpha-hydroxylase (CYP8B1) and expression in fetal liver: comparison with expression of taurochenodeoxycholic acid 6alpha-hydroxylase (CYP4A21).

Journal: Biochimica et biophysica acta 20031115

Title: Steroids in the intestinal tract of rats are affected by dietary-fibre-rich barley-based diets.

Journal: The British journal of nutrition 20031101

Title: Effect of beta-muricholic acid on the prevention and dissolution of cholesterol gallstones in C57L/J mice.

Journal: Journal of lipid research 20021101

Title: Ontogenetic development and spatial distribution of the ileal apical sodium-dependent bile acid transporter and the ileal lipid-binding protein in apoE knockout and C57BL/6 mice.

Journal: Scandinavian journal of gastroenterology 20020901

Title: Hepatoprotection with tauroursodeoxycholate and beta muricholate against taurolithocholate induced cholestasis: involvement of signal transduction pathways.

Journal: Gut 20020701

Title: Differences in the efficacy of ursodeoxycholic acid and bile acid metabolism between viral liver diseases and primary biliary cirrhosis.

Journal: Journal of gastroenterology and hepatology 20010501

Title: Metabolism and effects on cholestasis of isoursodeoxycholic and ursodeoxycholic acids in bile duct ligated rats.

Journal: Biochimica et biophysica acta 20010403

Title: Eyssen HJ, et al. Sulfate bile acids in germ-free and conventional mice. Eur J Biochem. 1976 Jul 15;66(3):507-14.

Title: Watanabe K, et al. Dietary soybean protein ameliorates high-fat diet-induced obesity by modifying the gut microbiota-dependent biotransformation of bile acids. PLoS One. 2018 Aug 13;13(8):e0202083.

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Tags:2393-58-0 Molecular Formula|2393-58-0 MDL|2393-58-0 SMILES|2393-58-0 (3a,5b,6b,7a)-3,6,7-trihydroxy-Cholan-24-oic acid