Title: GABA(A) receptor subtype selectivity of the proconvulsant rodenticide TETS.
Journal: Archives of toxicology 20180201
Title: Important roles of the AKR1C2 and SRD5A1 enzymes in progesterone metabolism in endometrial cancer model cell lines.
Journal: Chemico-biological interactions 20150605
Title: Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships.
Journal: Chemico-biological interactions 20150605
Title: Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype.
Journal: Hepatology (Baltimore, Md.) 20130201
Title: Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20121201
Title: Allopregnanolone regulates neurogenesis and depressive/anxiety-like behaviour in a social isolation rodent model of chronic stress.
Journal: Neuropharmacology 20121201
Title: Responses to sulfated steroids of female mouse vomeronasal sensory neurons.
Journal: Chemical senses 20121101
Title: Comparative molecular field analysis to derive pharmacophore maps for disposition parameters of intravenous anaesthetic agents.
Journal: British journal of anaesthesia 20121001
Title: Neuroactive steroids with perfluorobenzoyl group.
Journal: Steroids 20121001
Title: Steroid hormones and sleep regulation.
Journal: Mini reviews in medicinal chemistry 20121001
Title: Discriminative stimulus effects of pregnanolone in rats: role of training dose in determining mechanism of action.
Journal: Psychopharmacology 20120901
Title: Effect of ganaxolone and THIP on operant and limited-access ethanol self-administration.
Journal: Neuropharmacology 20120901
Title: Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice.
Journal: Neurobiology of aging 20120801
Title: Allopregnanolone protects against dopamine-induced striatal damage after in vitro ischaemia via interaction at GABA A receptors.
Journal: Journal of neuroendocrinology 20120801
Title: Long-term administration with levonorgestrel decreases allopregnanolone levels and alters GABA(A) receptor subunit expression and anxiety-like behavior.
Journal: Pharmacology, biochemistry, and behavior 20120801
Title: Progesterone receptors: a key for neuroprotection in experimental stroke.
Journal: Endocrinology 20120801
Title: Clustered burst firing in FMR1 premutation hippocampal neurons: amelioration with allopregnanolone.
Journal: Human molecular genetics 20120701
Title: Allopregnanolone alters the luteinizing hormone, prolactin, and progesterone serum levels interfering with the regression and apoptosis in rat corpus luteum.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20120701
Title: Regulation of the surface expression of α4β2δ GABAA receptors by high efficacy states.
Journal: Brain research 20120629
Title: Neurosteroid biosynthesis and action during cerebellar development.
Journal: Cerebellum (London, England) 20120601
Title: A mouse kindling model of perimenstrual catamenial epilepsy.
Journal: The Journal of pharmacology and experimental therapeutics 20120601
Title: Neurosteroid binding to the amino terminal and glutamate binding domains of ionotropic glutamate receptors.
Journal: Steroids 20120601
Title: Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice.
Journal: The journal of pain : official journal of the American Pain Society 20120601
Title: The influence of social subordinate housing on the withdrawal effects from progesterone and estradiol in male rats.
Journal: General and comparative endocrinology 20120515
Title: Allopregnanolone increases the number of dopaminergic neurons in substantia nigra of a triple transgenic mouse model of Alzheimer's disease.
Journal: Current Alzheimer research 20120501
Title: Effects of koumine, an alkaloid of Gelsemium elegans Benth., on inflammatory and neuropathic pain models and possible mechanism with allopregnanolone.
Journal: Pharmacology, biochemistry, and behavior 20120501
Title: Neurosteroid allopregnanolone regulates EAAC1-mediated glutamate uptake and triggers actin changes in Schwann cells.
Journal: Journal of cellular physiology 20120401
Title: Allopregnanolone infused into the dorsal (CA1) hippocampus increases prepulse inhibition of startle response in Wistar rats.
Journal: Psychoneuroendocrinology 20120401
Title: Allopregnanolone and induction of endogenous opioid inhibition of oxytocin responses to immune stress in pregnant rats.
Journal: Journal of neuroendocrinology 20120401
Title: Allopregnanolone potentiates the glutamate-mediated seizures induced by 4-aminopyridine in rat hippocampus in vivo.
Journal: Neurochemical research 20120301
Title: Quantitative analyses of antagonism: combinations of midazolam and either flunitrazepam or pregnanolone in rhesus monkeys discriminating midazolam.
Journal: The Journal of pharmacology and experimental therapeutics 20120301
Title: Allopregnanolone prevents memory impairment: effect on mRNA expression and enzymatic activity of hippocampal 3-α hydroxysteroid oxide-reductase.
Journal: Brain research bulletin 20120210
Title: Allopregnanolone prevents dieldrin-induced NMDA receptor internalization and neurotoxicity by preserving GABA(A) receptor function.
Journal: Endocrinology 20120201
Title: Synthesis of deuterium labeled NMDA receptor inhibitor - 20-Oxo-5β-[9,12,12-(2)H(3)]pregnan-3α-yl-L-glutamyl 1-ester.
Journal: Steroids 20120201
Title: A neurosteroid analogue photolabeling reagent labels the colchicine-binding site on tubulin: a mass spectrometric analysis.
Journal: Electrophoresis 20120201
Title: Allopregnanolone infusion induced neurobehavioural alterations in a neonatal foal: is this a clue to the pathogenesis of neonatal maladjustment syndrome?
Journal: Equine veterinary journal. Supplement 20120201
Title: Effect of maternal administration of allopregnanolone before birth asphyxia on neonatal hippocampal function in the spiny mouse.
Journal: Brain research 20120118
Title: Investigation of the mechanisms of progesterone protection following oxygen-glucose deprivation in organotypic hippocampal slice cultures.
Journal: Neuroscience letters 20120106
Title: Reinstatement of methamphetamine seeking in male and female rats treated with modafinil and allopregnanolone.
Journal: Drug and alcohol dependence 20120101
Title: Implication of allopregnanolone in the antinociceptive effect of N-palmitoylethanolamide in acute or persistent pain.
Journal: Pain 20120101
Title: Up-regulation of neurosteroid biosynthesis as a pharmacological strategy to improve behavioural deficits in a putative mouse model of post-traumatic stress disorder.
Journal: Journal of neuroendocrinology 20120101
Title: Pregnenolone sulphate-independent inhibition of TRPM3 channels by progesterone.
Journal: Cell calcium 20120101
Title: A thickening network of lipids.
Journal: Pain 20120101
Title: Progesterone and allopregnanolone exacerbate hypoxic-ischemic brain injury in immature rats.
Journal: Experimental neurology 20120101
Title: Assessment of estrus cyclicity in the Asian elephant (Elephas maximus) by measurement of fecal progesterone metabolite 5α-P-3OH, using a non-invasive assay.
Journal: General and comparative endocrinology 20120101
Title: Effects of early postnatal allopregnanolone administration on elevated plus maze anxiety scores in adult male Wistar rats.
Journal: Neuropsychobiology 20120101
Title: The neurosteroids, allopregnanolone and progesterone, induce autophagy in cultured astrocytes.
Journal: Neurochemistry international 20120101
Title: Chronic cigarette smoking alters circulating sex hormones and neuroactive steroids in premenopausal women.
Journal: Physiological research 20120101
Title: Chronic allopregnanolone treatment accelerates Alzheimer's disease development in AβPP(Swe)PSEN1(ΔE9) mice.
Journal: Journal of Alzheimer's disease : JAD 20120101
Title: Epilepsy: Novel therapeutic targets.
Journal: Journal of pharmacology & pharmacotherapeutics 20120101
Title: Regulation of neurosteroid biosynthesis by neurotransmitters and neuropeptides.
Journal: Frontiers in endocrinology 20120101
Title: Neurosteroid influences on sensitivity to ethanol.
Journal: Frontiers in endocrinology 20120101
Title: Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).
Journal: PloS one 20120101
Title: The involvement of the neurosteroid allopregnanolone in the antihyperalgesic effect of paroxetine in a rat model of neuropathic pain.
Journal: Neuroreport 20111221
Title: Allopregnanolone, a GABAA receptor agonist, decreases gonadotropin levels in women. A preliminary study.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20111201
Title: Chronic administration of the anabolic androgenic steroid nandrolone alters neurosteroid action at the sigma-1 receptor but not at the sigma-2 or NMDA receptors.
Journal: Neuropharmacology 20111201
Title: Clinical and metabolic findings in a 6-year-old boy with a Leydig cell tumour.
Journal: Acta paediatrica (Oslo, Norway : 1992) 20111201
Title: Role of the neurosteroid allopregnanolone in the hyperalgesic behavior induced by painful nerve injury in rats.
Journal: Journal of anesthesia 20111201
Title: Localization of brain 5α-reductase messenger RNA in mice selectively bred for high chronic alcohol withdrawal severity.
Journal: Alcohol (Fayetteville, N.Y.) 20111201
Title: Modulation of presynaptic GABA(A) receptors by endogenous neurosteroids.
Journal: British journal of pharmacology 20111101
Title: Alteration of ethanol drinking in mice via modulation of the GABA(A) receptor with ganaxolone, finasteride, and gaboxadol.
Journal: Alcoholism, clinical and experimental research 20111101
Title: Infusions of allopregnanolone into the hippocampus and amygdala, but not into the nucleus accumbens and medial prefrontal cortex, produce antidepressant effects on the learned helplessness rats.
Journal: Hippocampus 20111001
Title: Changes in functioning of mesolimbic incentive processing circuits during the premenstrual phase.
Journal: Social cognitive and affective neuroscience 20111001
Title: Neurosteroids infusion into the CA1 hippocampal region on exploration, anxiety-like behaviour and aversive learning.
Journal: Behavioural brain research 20110912
Title: Differential modulation of the glutamate-nitric oxide-cyclic GMP pathway by distinct neurosteroids in cerebellum in vivo.
Journal: Neuroscience 20110908
Title: Neuropharmacological properties of neurons derived from human stem cells.
Journal: Neurochemistry international 20110901
Title: AKR1C4 gene variant associated with low euthymic serum progesterone and a history of mood irritability in males with bipolar disorder.
Journal: Journal of affective disorders 20110901
Title: Sex difference in sensitivity to allopregnanolone neuroprotection in mice correlates with effect on spontaneous inhibitory post synaptic currents.
Journal: Neuropharmacology 20110901
Title: Effects of pregnanolone and flunitrazepam on the retention of response sequences in rats.
Journal: Pharmacology, biochemistry, and behavior 20110901
Title: Impaired neurosteroid synthesis in multiple sclerosis.
Journal: Brain : a journal of neurology 20110901
Title: Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110803
Title: The effect of age on the discriminative stimulus effects of ethanol and its GABA(A) receptor mediation in cynomolgus monkeys.
Journal: Psychopharmacology 20110801
Title: Hormonal therapy for epilepsy.
Journal: Current neurology and neuroscience reports 20110801
Title: Allopregnanolone induces LHRH and glutamate release through NMDA receptor modulation.
Journal: Endocrine 20110801
Title: Effect of acute ethanol and acute allopregnanolone on spatial memory in adolescent and adult rats.
Journal: Alcohol (Fayetteville, N.Y.) 20110801
Title: Occupation of either site for the neurosteroid allopregnanolone potentiates the opening of the GABAA receptor induced from either transmitter binding site.
Journal: Molecular pharmacology 20110701
Title: Palmitoylethanolamide stimulation induces allopregnanolone synthesis in C6 Cells and primary astrocytes: involvement of peroxisome-proliferator activated receptor-α.
Journal: Journal of neuroendocrinology 20110701
Title: Mechanisms responsible for progesterone's protection against lordosis-inhibiting effects of restraint II. Role of progesterone metabolites.
Journal: Hormones and behavior 20110701
Title: S-norfluoxetine microinfused into the basolateral amygdala increases allopregnanolone levels and reduces aggression in socially isolated mice.
Journal: Neuropharmacology 20110601
Title: Isolation rearing-induced reduction of brain 5α-reductase expression: relevance to dopaminergic impairments.
Journal: Neuropharmacology 20110601
Title: Anticonflict and reinforcing effects of triazolam + pregnanolone combinations in rhesus monkeys.
Journal: The Journal of pharmacology and experimental therapeutics 20110601
Title: Neurosteroid modulation of benzodiazepine-sensitive GABAA tonic inhibition in supraoptic magnocellular neurons.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20110601
Title: Effects of voluntary ethanol consumption on emotional state and stress responsiveness in socially isolated rats.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20110501
Title: [Effects of neuroactive steroid allopregnanolone on the damage of cortical neurons].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20110501
Title: Stereo-selective inhibition of transient receptor potential TRPC5 cation channels by neuroactive steroids.
Journal: British journal of pharmacology 20110401
Title: Comparing the discriminative stimuli produced by either the neuroactive steroid pregnanolone or the benzodiazepine midazolam in rats.
Journal: Psychopharmacology 20110301
Title: Sex-dependent effect of a low neurosteroid environment and intrauterine growth restriction on foetal guinea pig brain development.
Journal: The Journal of endocrinology 20110301
Title: Environmental enrichment alters gene expression of steroidogenic enzymes in the rat hippocampus.
Journal: General and comparative endocrinology 20110301
Title: Multiple effects of allopregnanolone on GABAergic responses in single hippocampal CA3 pyramidal neurons.
Journal: European journal of pharmacology 20110210
Title: Chronic benzodiazepine treatment does not alter interactions between positive GABA(A) modulators and flumazenil or pentylenetetrazole in monkeys.
Journal: Behavioural pharmacology 20110201
Title: Interaction between early postnatal neurosteroid manipulations and adult infusion of neurosteroids into CA1 hippocampal region on the open field behaviour.
Journal: Behavioural brain research 20110120
Title: Differential effects of two major neurosteroids on cerebellar and cortical GABA(A) receptor binding and function.
Journal: European journal of pharmacology 20110110
Title: Comparative Analysis of Gelsemine and Gelsemium sempervirens Activity on Neurosteroid Allopregnanolone Formation in the Spinal Cord and Limbic System.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Allopregnanolone levels decrease after gonadotropin-releasing hormone analog stimulation test in girls with central precocious puberty.
Journal: Journal of endocrinological investigation 20110101
Title: Allopregnanolone and suppressed hypothalamo-pituitary-adrenal axis stress responses in late pregnancy in the rat.
Journal: Stress (Amsterdam, Netherlands) 20110101
Title: Tolerance to allopregnanolone with focus on the GABA-A receptor.
Journal: British journal of pharmacology 20110101
Title: Circulating levels of allopregnanolone, a neuroactive steroid, and leptin during treatment with valproic acid in children with epilepsy.
Journal: Neuroendocrinology 20110101
Title: Juvenile offspring of rats exposed to restraint stress in late gestation have impaired cognitive performance and dysregulated progestogen formation.
Journal: Stress (Amsterdam, Netherlands) 20110101
Title: Progesterone turnover to its 5α-reduced metabolites in the ventral tegmental area of the midbrain is essential for initiating social and affective behavior and progesterone metabolism in female rats.
Journal: Journal of endocrinological investigation 20110101
Title: Allopregnanolone prevents and suppresses oxaliplatin-evoked painful neuropathy: multi-parametric assessment and direct evidence.
Journal: Pain 20110101
Title: Preclinical pharmacokinetics, dose proportionality, gender difference and protein binding study of 16-dehydropregnenolone, an antihyperlipidemic agent, in rats.
Journal: The Journal of pharmacy and pharmacology 20110101
Title: Neurosteroids for a successful pregnancy.
Journal: Stress (Amsterdam, Netherlands) 20110101
Title: Neuroprotective effects of progesterone and allopregnanolone on long-term cognitive outcome after global cerebral ischemia.
Journal: Restorative neurology and neuroscience 20110101
Title: Cellular and behavioural effects of a new steroidal inhibitor of the N-methyl-d-aspartate receptor 3α5β-pregnanolone glutamate.
Journal: Neuropharmacology 20110101
Title: Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease.
Journal: PloS one 20110101
Title: Neurosteroid Binding Sites on the GABA(A) Receptor Complex as Novel Targets for Therapeutics to Reduce Alcohol Abuse and Dependence.
Journal: Advances in pharmacological sciences 20110101
Title: Corneal alterations during combined therapy with cyclodextrin/allopregnanolone and miglustat in a knock-out mouse model of NPC1 disease.
Journal: PloS one 20110101
Title: Chirality and anaesthetic drugs: A review and an update.
Journal: Indian journal of anaesthesia 20110101
Title: Role of aldo-keto reductase enzymes in mediating the timing of parturition.
Journal: Frontiers in pharmacology 20110101
Title: Effects and Mechanisms of 3α,5α,-THP on Emotion, Motivation, and Reward Functions Involving Pregnane Xenobiotic Receptor.
Journal: Frontiers in neuroscience 20110101
Title: Beyond the HPA Axis: Progesterone-Derived Neuroactive Steroids in Human Stress and Emotion.
Journal: Frontiers in endocrinology 20110101
Title: Role of anticonvulsant and antiepileptogenic neurosteroids in the pathophysiology and treatment of epilepsy.
Journal: Frontiers in endocrinology 20110101
Title: Neurosteroids and GABA-A Receptor Function.
Journal: Frontiers in endocrinology 20110101
Title: Neurosteroids as neuromodulators in the treatment of anxiety disorders.
Journal: Frontiers in endocrinology 20110101
Title: Oxidative Stress-Mediated Brain Dehydroepiandrosterone (DHEA) Formation in Alzheimer's Disease Diagnosis.
Journal: Frontiers in endocrinology 20110101
Title: Midazolam inhibits hippocampal long-term potentiation and learning through dual central and peripheral benzodiazepine receptor activation and neurosteroidogenesis.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20101215
Title: Pregnenolone and ganaxolone reduce operant ethanol self-administration in alcohol-preferring p rats.
Journal: Alcoholism, clinical and experimental research 20101201
Title: Low brain allopregnanolone levels mediate flattened circadian activity associated with memory impairments in aged rats.
Journal: Biological psychiatry 20101115
Title: The role of progestins in the behavioral effects of cocaine and other drugs of abuse: human and animal research.
Journal: Neuroscience and biobehavioral reviews 20101101
Title: Receptors with low affinity for neurosteroids and GABA contribute to tonic inhibition of granule cells in epileptic animals.
Journal: Neurobiology of disease 20101101
Title: Progesterone and allopregnanolone attenuate blood-brain barrier dysfunction following permanent focal ischemia by regulating the expression of matrix metalloproteinases.
Journal: Experimental neurology 20101101
Title: Allosteric modulation of the NMDA receptor by neurosteroids in rat brain and the impact of long term morphine administration.
Journal: Biochemical and biophysical research communications 20101029
Title: Neurosteroid withdrawal regulates GABA-A receptor α4-subunit expression and seizure susceptibility by activation of progesterone receptor-independent early growth response factor-3 pathway.
Journal: Neuroscience 20101027
Title: Differential effects of allopregnanolone on the escalation of cocaine self-administration and sucrose intake in female rats.
Journal: Psychopharmacology 20101001
Title: Neurosteroids and self-reported pain in veterans who served in the U.S. Military after September 11, 2001.
Journal: Pain medicine (Malden, Mass.) 20101001
Title: Adaptation to extreme stress: post-traumatic stress disorder, neuropeptide Y and metabolic syndrome.
Journal: Experimental biology and medicine (Maywood, N.J.) 20101001
Title: Cellular and functional evidence for a protective action of neurosteroids against vincristine chemotherapy-induced painful neuropathy.
Journal: Cellular and molecular life sciences : CMLS 20100901
Title: Metformin administration restores allopregnanolone response to adrenocorticotropic hormone (ACTH) stimulation in overweight hyperinsulinemic patients with PCOS.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20100901
Title: Factorizing the role of a critical leucine residue in the binding of substrate to human 20alpha-hydroxysteroid dehydrogenase (AKR1C1): molecular modeling and kinetic studies of the Leu308Val mutant enzyme.
Journal: Bioorganic & medicinal chemistry letters 20100901
Title: In a mouse model relevant for post-traumatic stress disorder, selective brain steroidogenic stimulants (SBSS) improve behavioral deficits by normalizing allopregnanolone biosynthesis.
Journal: Behavioural pharmacology 20100901
Title: Fluoxetine-induced decrements in sexual responses of female rats and hamsters are reversed by 3α,5α-THP.
Journal: The journal of sexual medicine 20100801
Title: Allopregnanolone levels are reduced in temporal cortex in patients with Alzheimer's disease compared to cognitively intact control subjects.
Journal: Biochimica et biophysica acta 20100801
Title: Naltrexone selectively elevates GABAergic neuroactive steroid levels in heavy drinkers with the Asp40 allele of the OPRM1 gene: a pilot investigation.
Journal: Alcoholism, clinical and experimental research 20100801
Title: A role for Src kinase in progestin facilitation of estrous behavior in estradiol-primed female rats.
Journal: Hormones and behavior 20100701
Title: Acute neurosteroids inhibit the spinal reflex potentiation via GABAergic neurotransmission.
Journal: American journal of physiology. Renal physiology 20100701
Title: New therapeutic approaches for epilepsies, focusing on reorganization of the GABAA receptor subunits by neurosteroids.
Journal: Epilepsia 20100701
Title: Neonatal exposure to estradiol in rats influences neuroactive steroid concentrations, GABAA receptor expression, and behavioral sensitivity to anxiolytic drugs.
Journal: Journal of neurochemistry 20100601
Title: Mechanisms involved in the modulation of astroglial resistance to oxidative stress induced by activated microglia: antioxidative systems, peroxide elimination, radical generation, lipid peroxidation.
Journal: Neurotoxicity research 20100501
Title: Alterations in neonatal neurosteroids affect exploration during adolescence and prepulse inhibition in adulthood.
Journal: Psychoneuroendocrinology 20100501
Title: Treatment with progesterone after focal cerebral ischemia suppresses proliferation of progenitor cells but enhances survival of newborn neurons in adult male mice.
Journal: Neuropharmacology 20100501
Title: Ganaxolone suppression of behavioral and electrographic seizures in the mouse amygdala kindling model.
Journal: Epilepsy research 20100501
Title: Do 5-alpha reductase inhibitors influence the severity of brain injury in men after a stroke?
Journal: Medical hypotheses 20100501
Title: Prediction of estrus cyclicity in Asian elephants (Elephas maximus) through estimation of fecal progesterone metabolite: development of an enzyme-linked immuno-sorbent assay.
Journal: Theriogenology 20100501
Title: Endogenous neurosteroid synthesis modulates seizure frequency.
Journal: Annals of neurology 20100501
Title: Site-specific fluorescence reveals distinct structural changes induced in the human rho 1 GABA receptor by inhibitory neurosteroids.
Journal: Molecular pharmacology 20100401
Title: Low doses of cocaine decrease, and high doses increase, anxiety-like behavior and brain progestogen levels among intact rats.
Journal: Hormones and behavior 20100401
Title: A critical role for alpha4betadelta GABAA receptors in shaping learning deficits at puberty in mice.
Journal: Science (New York, N.Y.) 20100319
Title: Replacement with GABAergic steroid precursors restores the acute ethanol withdrawal profile in adrenalectomy/gonadectomy mice.
Journal: Neuroscience 20100310
Title: Neuropeptide Y Y1 receptors in the central nucleus of amygdala mediate the anxiolytic-like effect of allopregnanolone in mice: Behavioral and immunocytochemical evidences.
Journal: Brain research 20100308
Title: A residue in loop 9 of the beta2-subunit stabilizes the closed state of the GABAA receptor.
Journal: The Journal of biological chemistry 20100305
Title: Palmitoylethanolamide modulates pentobarbital-evoked hypnotic effect in mice: involvement of allopregnanolone biosynthesis.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20100301
Title: Sex differences in the effects of allopregnanolone on yohimbine-induced reinstatement of cocaine seeking in rats.
Journal: Drug and alcohol dependence 20100301
Title: Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans.
Journal: Alcoholism, clinical and experimental research 20100301
Title: The effect of betamethasone treatment on neuroactive steroid synthesis in a foetal Guinea pig model of growth restriction.
Journal: Journal of neuroendocrinology 20100301
Title: Kinetic and structural determinants for GABA-A receptor potentiation by neuroactive steroids.
Journal: Current neuropharmacology 20100301
Title: Effects of gestational allopregnanolone administration in rats bred for high affective behavior.
Journal: Physiology & behavior 20100209
Title: Neuroactive steroids after estrogen exposure in depressed postmenopausal women treated with sertraline and asymptomatic postmenopausal women.
Journal: Archives of women's mental health 20100201
Title: GABA synthesis in Schwann cells is induced by the neuroactive steroid allopregnanolone.
Journal: Journal of neurochemistry 20100201
Title: Dopamine is involved in the antidepressant-like effect of allopregnanolone in the forced swimming test in female rats.
Journal: Behavioural pharmacology 20100201
Title: Ethanol induction of steroidogenesis in rat adrenal and brain is dependent upon pituitary ACTH release and de novo adrenal StAR synthesis.
Journal: Journal of neurochemistry 20100201
Title: Premenstrual dysphoric disorder: out of the appendix.
Journal: Archives of women's mental health 20100201
Title: Two new terpenoids from Trichilia quadrijuga (Meliaceae).
Journal: Natural product communications 20100201
Title: Anticonvulsant doses of ganaxolone do not compromise motor performance in immature rats.
Journal: Neuroscience letters 20100129
Title: Anticonvulsant action of a new analogue of allopregnanolone in immature rats.
Journal: Physiological research 20100101
Title: Manipulation of GABAergic steroids: Sex differences in the effects on alcohol drinking- and withdrawal-related behaviors.
Journal: Hormones and behavior 20100101
Title: Neural mechanisms underlying changes in stress-sensitivity across the menstrual cycle.
Journal: Psychoneuroendocrinology 20100101
Title: Acute experimental autoimmune encephalomyelitis induces sex dimorphic changes in neuroactive steroid levels.
Journal: Neurochemistry international 20100101
Title: Allopregnanolone, the active metabolite of progesterone protects against neuronal damage in picrotoxin-induced seizure model in mice.
Journal: Pharmacology, biochemistry, and behavior 20100101
Title: Surgical management of placenta accreta: a cohort series and suggested approach.
Journal: American journal of obstetrics and gynecology 20100101
Title: Neurosteroids: endogenous role in the human brain and therapeutic potentials.
Journal: Progress in brain research 20100101
Title: Allopregnanolone effects on astrogliosis induced by hypoxia in organotypic cultures of striatum, hippocampus, and neocortex.
Journal: Brain research 20091215
Title: Puberty, steroids and GABA(A) receptor plasticity.
Journal: Psychoneuroendocrinology 20091201
Title: Plasticity and function of extrasynaptic GABA(A) receptors during pregnancy and after delivery.
Journal: Psychoneuroendocrinology 20091201
Title: Neurosteroids' effects and mechanisms for social, cognitive, emotional, and physical functions.
Journal: Psychoneuroendocrinology 20091201
Title: Selected line difference in the effects of ethanol dependence and withdrawal on allopregnanolone levels and 5alpha-reductase enzyme activity and expression.
Journal: Alcoholism, clinical and experimental research 20091201
Title: Plasticity of the alpha4betadelta GABAA receptor.
Journal: Biochemical Society transactions 20091201
Title: Progesterone and allopregnanolone enhance the miniature synaptic release of glycine in the rat hypoglossal nucleus.
Journal: The European journal of neuroscience 20091201
Title: The effects of acute and chronic ethanol exposure on presynaptic and postsynaptic gamma-aminobutyric acid (GABA) neurotransmission in cultured cortical and hippocampal neurons.
Journal: Alcohol (Fayetteville, N.Y.) 20091201
Title: Challenges predicting ligand-receptor interactions of promiscuous proteins: the nuclear receptor PXR.
Journal: PLoS computational biology 20091201
Title: Alpha-methyltyrosine inhibits formation of reactive oxygen species and diminishes apoptosis in PC12 cells.
Journal: Brain research 20091103
Title: The role of neuroactive steroids in ethanol/stress interactions: proceedings of symposium VII at the Volterra conference on alcohol and stress, May 2008.
Journal: Alcohol (Fayetteville, N.Y.) 20091101
Title: Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain.
Journal: Neuroscience 20091020
Title: Development and screening of water-soluble analogues of progesterone and allopregnanolone in models of brain injury.
Journal: Journal of medicinal chemistry 20091008
Title: Neonatal allopregnanolone increases novelty-directed locomotion and disrupts behavioural responses to GABA(A) receptor modulators in adulthood.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20091001
Title: Neurosteroids modulate compulsive and persistent behavior in rodents: implications for obsessive-compulsive disorder.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20091001
Title: Olanzapine plus 17-beta estradiol produce antidepressant-like actions in rats forced to swim.
Journal: Pharmacology, biochemistry, and behavior 20091001
Title: Allopregnanolone microinjected into the lateral septum or dorsal hippocampus reduces immobility in the forced swim test: participation of the GABAA receptor.
Journal: Behavioural pharmacology 20091001
Title: Synthesis and GABA(A) receptor activity of 2,19-sulfamoyl analogues of allopregnanolone.
Journal: Bioorganic & medicinal chemistry 20090915
Title: Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone.
Journal: Journal of cellular and molecular medicine 20090901
Title: Sex steroid induced negative mood may be explained by the paradoxical effect mediated by GABAA modulators.
Journal: Psychoneuroendocrinology 20090901
Title: 17beta-Nitro-5alpha-androstan-3alpha-ol and its 3beta-methyl derivative: neurosteroid analogs with potent anticonvulsant and anxiolytic activities.
Journal: European journal of pharmacology 20090901
Title: Trilostane exerts antidepressive effects among wild-type, but not estrogen receptor [beta] knockout mice.
Journal: Neuroreport 20090805
Title: Evaluation of putative inhibitors of mitochondrial permeability transition for brain disorders--specificity vs. toxicity.
Journal: Experimental neurology 20090801
Title: Central modifications of allopregnanolone and beta-endorphin following subcutaneous administration of Nestorone.
Journal: The Journal of steroid biochemistry and molecular biology 20090801
Title: Progesterone receptor A (PRA) and PRB-independent effects of progesterone on gonadotropin-releasing hormone release.
Journal: Endocrinology 20090801
Title: The influence of neuroactive steroid lipophilicity on GABAA receptor modulation: evidence for a low-affinity interaction.
Journal: Journal of neurophysiology 20090801
Title: Allopregnanolone levels before and after selective serotonin reuptake inhibitor treatment of premenstrual symptoms.
Journal: Journal of clinical psychopharmacology 20090801
Title: Excitability changes related to GABAA receptor plasticity during pregnancy.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090729
Title: Selective changes in sensitivity to benzodiazepines, and not other positive GABA(A) modulators, in rats receiving flunitrazepam chronically.
Journal: Psychopharmacology 20090701
Title: Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090701
Title: Effects of pregnanolone and dehydroepiandrosterone on ethanol intake in rats administered ethanol or saline during adolescence.
Journal: Alcoholism, clinical and experimental research 20090701
Title: Discriminative stimulus effects of ethanol, pregnanolone, and dehydroepiandrosterone (DHEA) in rats administered ethanol or saline as adolescents.
Journal: Pharmacology, biochemistry, and behavior 20090701
Title: Neurosteroids differentially modulate P2X ATP-gated channels through non-genomic interactions.
Journal: Journal of neurochemistry 20090701
Title: Selective effect of chlormadinone acetate on brain allopregnanolone and opioids content.
Journal: Contraception 20090701
Title: Biphasic effects of neonatal allopregnanolone on striatal dopamine metabolism.
Journal: Neuroreport 20090617
Title: NMDA potentiation by visible light in the presence of a fluorescent neurosteroid analogue.
Journal: The Journal of physiology 20090615
Title: Allopregnanolone has no effect on startle response and prepulse inhibition of startle response in patients with premenstrual dysphoric disorder or healthy controls.
Journal: Pharmacology, biochemistry, and behavior 20090601
Title: Activation and modulation of concatemeric GABA-A receptors expressed in human embryonic kidney cells.
Journal: Molecular pharmacology 20090601
Title: Pregnanolone sulfate promotes desensitization of activated NMDA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527
Title: Central opioid inhibition of neuroendocrine stress responses in pregnancy in the rat is induced by the neurosteroid allopregnanolone.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090520
Title: Allopregnanolone treatment delays cholesterol accumulation and reduces autophagic/lysosomal dysfunction and inflammation in Npc1-/- mouse brain.
Journal: Brain research 20090513
Title: Peripheral-type benzodiazepine receptor antagonist is effective in relieving neuropathic pain in mice.
Journal: Journal of pharmacological sciences 20090501
Title: Enhanced fear responses in mice treated with anabolic androgenic steroids.
Journal: Neuroreport 20090422
Title: Progestogens and brain: an update.
Journal: Maturitas 20090420
Title: Allopregnanolone (3alpha-hydroxy-5alpha-pregnan-20-one) derivatives with a polar chain in position 16alpha: synthesis and activity.
Journal: Journal of medicinal chemistry 20090409
Title: Hyperammonemia increases GABAergic tone in the cerebellum but decreases it in the rat cortex.
Journal: Gastroenterology 20090401
Title: Neurosteroid replacement therapy for catamenial epilepsy.
Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20090401
Title: Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism for better neuroprotective effects of allopregnanolone over progesterone.
Journal: Brain research 20090331
Title: Hormonal, cardiovascular, and subjective responses to acute stress in smokers.
Journal: Psychopharmacology 20090301
Title: Studies of pharmacokinetic and pharmacodynamic properties of isoallopregnanolone in healthy women.
Journal: Psychopharmacology 20090301
Title: Effects of allopregnanolone on the reinstatement of cocaine-seeking behavior in male and female rats.
Journal: Psychopharmacology 20090301
Title: Kinetic analysis of voltage-dependent potentiation and block of the glycine alpha 3 receptor by a neuroactive steroid analogue.
Journal: The Journal of physiology 20090301
Title: Measurement of ring A-reduced progesterone metabolites by enzyme-linked immunoassay with colorimetric detection: baseline levels of six metabolites, including pregnanolone, in male rat plasma.
Journal: Analytical chemistry 20090201
Title: SSRIs act as selective brain steroidogenic stimulants (SBSSs) at low doses that are inactive on 5-HT reuptake.
Journal: Current opinion in pharmacology 20090201
Title: Effects of bisphenol-A and other endocrine disruptors compared with abnormalities of schizophrenia: an endocrine-disruption theory of schizophrenia.
Journal: Schizophrenia bulletin 20090101
Title: Conserved site for neurosteroid modulation of GABA A receptors.
Journal: Neuropharmacology 20090101
Title: Increasing 3alpha,5alpha-THP following inhibition of neurosteroid biosynthesis in the ventral tegmental area reinstates anti-anxiety, social, and sexual behavior of naturally receptive rats.
Journal: Reproduction (Cambridge, England) 20090101
Title: Progesterone withdrawal-evoked plasticity of neural function in the female periaqueductal grey matter.
Journal: Neural plasticity 20090101
Title: Glycine receptor in rat hippocampal and spinal cord neurons as a molecular target for rapid actions of 17-beta-estradiol.
Journal: Molecular pain 20090101
Title: Structure-activity relationships of neuroactive steroids acting on the GABAA receptor.
Journal: Current medicinal chemistry 20090101
Title: Progesterone after previous preterm birth for prevention of neonatal respiratory distress syndrome (PROGRESS): a randomised controlled trial.
Journal: BMC pregnancy and childbirth 20090101
Title: Expression levels of the alpha4 subunit of the GABA(A) receptor in differentiated neuroblastoma cells are correlated with GABA-gated current.
Journal: Neuropharmacology 20090101
Title: Brain-region responsiveness to DT56a (Femarelle) administration on allopregnanolone and opioid content in ovariectomized rats.
Journal: Menopause (New York, N.Y.) 20090101
Title: Role of progesterone receptor isoforms in female sexual behavior induced by progestins in rats.
Journal: Neuroendocrinology 20090101
Title: GABA(A) receptor function and gene expression during pregnancy and postpartum.
Journal: International review of neurobiology 20090101
Title: Sex differences in acoustic startle responses and seizure thresholds between ethanol-withdrawn male and female rats.
Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20090101
Title: Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression.
Journal: PloS one 20090101
Title: The role of progesterone in prevention of preterm birth.
Journal: International journal of women's health 20090101
Title: A new cytotoxic pregnanone from Calotropis gigantea.
Journal: Molecules (Basel, Switzerland) 20081204
Title: The neurosteroid environment in the hippocampus exerts bi-directional effects on seizure susceptibility in mice.
Journal: Brain research 20081203
Title: Reinstatement of ethanol and sucrose seeking by the neurosteroid allopregnanolone in C57BL/6 mice.
Journal: Psychopharmacology 20081201
Title: Acute cross tolerance to midazolam, and not pentobarbital and pregnanolone, after a single dose of chlordiazepoxide in monkeys discriminating midazolam.
Journal: Behavioural pharmacology 20081201
Title: Sexually dimorphic effects of testosterone administration on brain allopregnanolone in gonadectomized rats.
Journal: The journal of sexual medicine 20081201
Title: Protein kinase Cdelta regulates ethanol intoxication and enhancement of GABA-stimulated tonic current.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20081112
Title: Progesterone and its metabolite allopregnanolone differentially regulate hemostatic proteins after traumatic brain injury.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20081101
Title: Ischemic insult to cerebellar Purkinje cells causes diminished GABAA receptor function and allopregnanolone neuroprotection is associated with GABAA receptor stabilization.
Journal: Journal of neurochemistry 20081101
Title: Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice.
Journal: Methods and findings in experimental and clinical pharmacology 20081101
Title: Fast non-genomic effects of progesterone-derived neurosteroids on nociceptive thresholds and pain symptoms.
Journal: Pain 20081031
Title: Neurosteroid biosynthesis regulates sexually dimorphic fear and aggressive behavior in mice.
Journal: Neurochemical research 20081001
Title: Role of acetaldehyde in ethanol-induced elevation of the neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one in rats.
Journal: Alcoholism, clinical and experimental research 20081001
Title: K+ channel TASK-1 knockout mice show enhanced sensitivities to ataxic and hypnotic effects of GABA(A) receptor ligands.
Journal: The Journal of pharmacology and experimental therapeutics 20081001
Title: Persistence of tolerance to the anaesthetic effect of allopregnanolone in male rats.
Journal: European journal of pharmacology 20080911
Title: Ethanol intake patterns in female mice: influence of allopregnanolone and the inhibition of its synthesis.
Journal: Drug and alcohol dependence 20080901
Title: MRI detects therapeutic effects in weanling Niemann-Pick type C mice.
Journal: Journal of neuroscience research 20080901
Title: Mutations of the GABA-A receptor alpha1 subunit M1 domain reveal unexpected complexity for modulation by neuroactive steroids.
Journal: Molecular pharmacology 20080901
Title: Neuroactive steroids and GABAA receptor plasticity in the brain of the WAG/Rij rat, a model of absence epilepsy.
Journal: Journal of neurochemistry 20080901
Title: Studies on neurosteroids XXV. Influence of a 5alpha-reductase inhibitor, finasteride, on rat brain neurosteroid levels and metabolism.
Journal: Biological & pharmaceutical bulletin 20080901
Title: Excitatory neurosteroids attenuate apoptotic and excitotoxic cell death in primary cortical neurons.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080901
Title: Antinociceptive profile of ring A-reduced progesterone metabolites in the formalin test.
Journal: Pain 20080831
Title: Menthol shares general anesthetic activity and sites of action on the GABA(A) receptor with the intravenous agent, propofol.
Journal: European journal of pharmacology 20080820
Title: Sex steroids effects on the content of GAD, TH, GABA(A), and glutamate receptors in the olfactory bulb of the male rat.
Journal: Neurochemical research 20080801
Title: Progesterone metabolites rapidly stimulate calcium influx in human platelets by a src-dependent pathway.
Journal: Steroids 20080801
Title: Indomethacin improves locomotor deficit and reduces brain concentrations of neuroinhibitory steroids in rats following portacaval anastomosis.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080801
Title: Allopregnanolone impairs episodic memory in healthy women.
Journal: Psychopharmacology 20080801
Title: Inhibition of 5alpha-reduced steroid biosynthesis impedes acquisition of ethanol drinking in male C57BL/6J mice.
Journal: Alcoholism, clinical and experimental research 20080801
Title: Neurosteroids allosterically modulate the ion pore of the NMDA receptor consisting of NR1/NR2B but not NR1/NR2A.
Journal: Biochemical and biophysical research communications 20080725
Title: Neonatal finasteride induces anxiogenic-like profile and deteriorates passive avoidance in adulthood after intrahippocampal neurosteroid administration.
Journal: Neuroscience 20080717
Title: GABA in the female brain -- oestrous cycle-related changes in GABAergic function in the periaqueductal grey matter.
Journal: Pharmacology, biochemistry, and behavior 20080701
Title: Antidepressant effect and changes of GABAA receptor gamma2 subunit mRNA after hippocampal administration of allopregnanolone in rats.
Journal: Journal of psychopharmacology (Oxford, England) 20080701
Title: Reduced serum level of THDOC, an anticonvulsant steroid, in women with perimenstrual catamenial epilepsy.
Journal: Epilepsia 20080701
Title: Olanzapine counteracts stress-induced anxiety-like behavior in rats.
Journal: Neuroscience letters 20080620
Title: Neuroactive steroids, mood stabilizers, and neuroplasticity: alterations following lithium and changes in Bcl-2 knockout mice.
Journal: The international journal of neuropsychopharmacology 20080601
Title: Neuroactive steroids and fatigue severity in patients with primary biliary cirrhosis and hepatitis C.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080601
Title: Dydrogesterone increases allopregnanolone in selected brain areas and in serum of female rats.
Journal: Fertility and sterility 20080501
Title: Effects of neurosteroids on hydrogen peroxide- and staurosporine-induced damage of human neuroblastoma SH-SY5Y cells.
Journal: Journal of neuroscience research 20080501
Title: Investigation of the anticonvulsive effect of acute immobilization stress in anxious Balb/cByJ mice using GABA A-related mechanistic probes.
Journal: Psychopharmacology 20080501
Title: Progesterone and allopregnanolone are induced by cocaine in serum and brain tissues of male and female rats.
Journal: Pharmacology, biochemistry, and behavior 20080501
Title: Overlapping, but not identical, discriminative stimulus effects of the neuroactive steroid pregnanolone and ethanol.
Journal: Pharmacology, biochemistry, and behavior 20080501
Title: Effects of nomegestrol acetate administration on central and peripheral beta-endorphin and allopregnanolone in ovx rats.
Journal: The Journal of steroid biochemistry and molecular biology 20080501
Title: 5Beta,6beta-epoxy-17-oxoandrostan-3beta-yl acetate and 5beta,6beta-epoxy-20-oxopregnan-3beta-yl acetate.
Journal: Acta crystallographica. Section C, Crystal structure communications 20080501
Title: Regulation of neurosteroid allopregnanolone biosynthesis in the rat spinal cord by glycine and the alkaloidal analogs strychnine and gelsemine.
Journal: Neuroscience 20080422
Title: One-year therapy with 10mg/day DHEA alone or in combination with HRT in postmenopausal women: effects on hormonal milieu.
Journal: Maturitas 20080420
Title: Involvement of neurosteroids in the anxiolytic-like effects of AC-5216 in mice.
Journal: Pharmacology, biochemistry, and behavior 20080401
Title: Synthesis and GABA(A) receptor activity of oxygen-bridged neurosteroid analogs.
Journal: Bioorganic & medicinal chemistry 20080401
Title: Progesterone selectively increases amygdala reactivity in women.
Journal: Molecular psychiatry 20080301
Title: Endogenous and synthetic neurosteroids in treatment of Niemann-Pick Type C disease.
Journal: Brain research reviews 20080301
Title: Regenerative potential of allopregnanolone.
Journal: Brain research reviews 20080301
Title: Genetic variations and treatments that affect the lifespan of the NPC1 mouse.
Journal: Journal of lipid research 20080301
Title: Neuroactive Steroid Levels in a transgenic rat model of CMT1A Neuropathy.
Journal: Journal of molecular neuroscience : MN 20080301
Title: Effect of psychotropic drugs on the 21-hydroxylation of neurosteroids, progesterone and allopregnanolone, catalyzed by rat CYP2D4 and human CYP2D6 in the brain.
Journal: Biological & pharmaceutical bulletin 20080301
Title: Alcohol related changes in regulation of NMDA receptor functions.
Journal: Current neuropharmacology 20080301
Title: Progesterone attenuates neuroleptic-induced orofacial dyskinesia via the activity of its metabolite, allopregnanolone, a positive GABA(A) modulating neurosteroid.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20080215
Title: Effects of swim stress on mRNA and protein levels of steroid 5alpha-reductase isozymes in prefrontal cortex of adult male rats.
Journal: Neurochemistry international 20080201
Title: Modulatory effect of neurosteroids in haloperidol-induced vacuous chewing movements and related behaviors.
Journal: Psychopharmacology 20080201
Title: Mechanisms of potentiation of the mammalian GABAA receptor by the marine cembranoid eupalmerin acetate.
Journal: British journal of pharmacology 20080201
Title: Decreased anticonvulsant efficacy of allopregnanolone during ethanol withdrawal in female Withdrawal Seizure-Prone vs. Withdrawal Seizure-Resistant mice.
Journal: Neuropharmacology 20080201
Title: Neurosteroid analogues. 12. Potent enhancement of GABA-mediated chloride currents at GABAA receptors by ent-androgens.
Journal: European journal of medicinal chemistry 20080101
Title: Neurosteroids in the fetus and neonate: potential protective role in compromised pregnancies.
Journal: Neurochemistry international 20080101
Title: Effects of progesterone administration and APPswe+PSEN1Deltae9 mutation for cognitive performance of mid-aged mice.
Journal: Neurobiology of learning and memory 20080101
Title: Etomidate and other non-barbiturates.
Journal: Handbook of experimental pharmacology 20080101
Title: [Discriminative stimulus properties of phenazepam and lorazepam: specificity and role of GABA A receptors].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20080101
Title: Neurosteroids in the Purkinje cell: biosynthesis, mode of action and functional significance.
Journal: Molecular neurobiology 20080101
Title: Induction of Akt by endogenous neurosteroids and calcium sequestration in P19 derived neurons.
Journal: Neurotoxicity research 20080101
Title: Brain allopregnanolone in the fetal and postnatal rat in response to uteroplacental insufficiency.
Journal: Neuroendocrinology 20080101
Title: Progestin receptor-mediated reduction of anxiety-like behavior in male rats.
Journal: PloS one 20080101
Title: Effect of an oral contraceptive with chlormadinone acetate on depressive mood : analysis of data from four observational studies.
Journal: Clinical drug investigation 20080101
Title: Transgenerational epigenetic programming of the brain transcriptome and anxiety behavior.
Journal: PloS one 20080101
Title: Allopregnanolone-induced rise in intracellular calcium in embryonic hippocampal neurons parallels their proliferative potential.
Journal: BMC neuroscience 20080101
Title: Interaction of diazepam and swim stress.
Journal: Brain research 20071212
Title: Neurosteroid allopregnanolone mediates anxiolytic effect of etifoxine in rats.
Journal: Brain research 20071212
Title: The neurosteroid system: an emerging therapeutic target for hepatic encephalopathy.
Journal: Metabolic brain disease 20071201
Title: Differential anesthetic activity of ketamine and the GABAergic neurosteroid allopregnanolone in mice lacking progesterone receptor A and B subtypes.
Journal: Methods and findings in experimental and clinical pharmacology 20071201
Title: Influence of epipregnanolone on the modulation of rapid tolerance to ethanol by neurosteroids.
Journal: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20071201
Title: Regeneration in a degenerating brain: potential of allopregnanolone as a neuroregenerative agent.
Journal: Current Alzheimer research 20071201
Title: Diminished neurosteroid sensitivity of synaptic inhibition and altered location of the alpha4 subunit of GABA(A) receptors in an animal model of epilepsy.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20071114
Title: Neurosteroid migration to intracellular compartments reduces steroid concentration in the membrane and diminishes GABA-A receptor potentiation.
Journal: The Journal of physiology 20071101
Title: [Neurological and psychiatric aspects of some endocrine diseases. The role of neurosteroids and neuroactive steroids].
Journal: Orvosi hetilap 20071014
Title: Neurosteroid regulation of GABA(A) receptors: Focus on the alpha4 and delta subunits.
Journal: Pharmacology & therapeutics 20071001
Title: Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility.
Journal: Pharmacology, biochemistry, and behavior 20071001
Title: Clinical evaluation of ganaxolone in pediatric and adolescent patients with refractory epilepsy.
Journal: Epilepsia 20071001
Title: Neurosteroid regulation of central nervous system development.
Journal: Pharmacology & therapeutics 20071001
Title: Allopregnanolone serum concentrations and neurosteroid sensitivity during withdrawal from postmenopausal hormone therapy.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20071001
Title: Relationships of circulating pregnanolone isomers and their polar conjugates to the status of sex, menstrual cycle, and pregnancy.
Journal: The Journal of endocrinology 20071001
Title: Neurosteroids reduce inflammation after TBI through CD55 induction.
Journal: Neuroscience letters 20070925
Title: GABAA and glycine receptor-mediated transmission in rat lamina II neurones: relevance to the analgesic actions of neuroactive steroids.
Journal: The Journal of physiology 20070915
Title: The relationship of allopregnanolone immunoreactivity and HPA-axis measures to experimental pain sensitivity: Evidence for ethnic differences.
Journal: Pain 20070901
Title: Estrogens and progestins enhance spatial learning of intact and ovariectomized rats in the object placement task.
Journal: Neurobiology of learning and memory 20070901
Title: Allopregnanolone modulates striatal dopamingergic activity of rats under different gonadal hormones conditions.
Journal: Neurological research 20070901
Title: The anxiolytic-like effects of allopregnanolone vary as a function of intracerebral microinfusion site: the amygdala, medial prefrontal cortex, or hippocampus.
Journal: Behavioural pharmacology 20070901
Title: Acute effects of neurosteroids in a rodent model of primary paroxysmal dystonia.
Journal: Hormones and behavior 20070801
Title: A 17beta-derivative of allopregnanolone is a neurosteroid antagonist at a cerebellar subpopulation of GABA A receptors with nanomolar affinity.
Journal: British journal of pharmacology 20070801
Title: Chronic progesterone treatment augments while dehydroepiandrosterone sulphate prevents tolerance to ethanol anxiolysis and withdrawal anxiety in rats.
Journal: European journal of pharmacology 20070719
Title: Inhibition of evoked glutamate release by neurosteroid allopregnanolone via inhibition of L-type calcium channels in rat medial prefrontal cortex.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070701
Title: Electrophysiological properties and subunit composition of GABAA receptors in patients with gelastic seizures and hypothalamic hamartoma.
Journal: Journal of neurophysiology 20070701
Title: Effects of combination treatment with mood stabilizers and mirtazapine on plasma concentrations of neuroactive steroids in depressed patients.
Journal: Psychoneuroendocrinology 20070701
Title: Neurosteroid modulation of neuronal excitability and synaptic transmission in the rat medial vestibular nuclei.
Journal: The European journal of neuroscience 20070701
Title: Inhibition of neurosteroid synthesis increases asphyxia-induced brain injury in the late gestation fetal sheep.
Journal: Neuroscience 20070608
Title: Microbial transformation of 5alpha,6alpha-epoxy-3beta-hydroxy-16-pregnen-20-one by Trichoderma viride.
Journal: Steroids 20070601
Title: Effects of allopregnanolone on sedation in men, and in women on oral contraceptives.
Journal: Psychoneuroendocrinology 20070601
Title: A novel chemical delivery system comprising an ocular sustained release formulation of a 3alpha, 17alpha, 21-trihydroxy-5beta-pregnan-20-one-BIS-5-fluorouracil [correction of flourouracil] codrug.
Journal: Drug development and industrial pharmacy 20070601
Title: Allopregnanolone influences the consummatory processes that govern ethanol drinking in C57BL/6J mice.
Journal: Behavioural brain research 20070516
Title: Intrahippocampal allopregnanolone decreases voluntary chronic alcohol consumption in non-selected rats.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20070509
Title: Changes in relative potency among positive GABA(A) receptor modulators upon discontinuation of chronic benzodiazepine treatment in rhesus monkeys.
Journal: Psychopharmacology 20070501
Title: Allopregnanolone decrease with symptom improvement during placebo and gonadotropin-releasing hormone agonist treatment in women with severe premenstrual syndrome.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20070501
Title: The neuroactive steroids alphaxalone and pregnanolone increase the conductance of single GABAA channels in newborn rat hippocampal neurons.
Journal: The Journal of steroid biochemistry and molecular biology 20070401
Title: Anticonvulsant and anesthetic effects of a fluorescent neurosteroid analog activated by visible light.
Journal: Nature neuroscience 20070401
Title: Reversal of neurosteroid effects at alpha4beta2delta GABAA receptors triggers anxiety at puberty.
Journal: Nature neuroscience 20070401
Title: Cellular distribution of the GABAA receptor-modulating 3alpha-hydroxy, 5alpha-reduced pregnane steroids in the adult rat brain.
Journal: Journal of neuroendocrinology 20070401
Title: Neurosteroid modulation of GABAergic neurotransmission in the central amygdala: a role for NMDA receptors.
Journal: Neuroscience letters 20070326
Title: High basal serum allopregnanolone levels in overweight girls.
Journal: International journal of obesity (2005) 20070301
Title: Neuroprotective effects of steroid analogues on P19-N neurons.
Journal: Neurochemistry international 20070301
Title: Engaging in paced mating, but neither exploratory, anti-anxiety, nor social behavior, increases 5alpha-reduced progestin concentrations in midbrain, hippocampus, striatum, and cortex.
Journal: Reproduction (Cambridge, England) 20070301
Title: Effects of progesterone and its reduced metabolites, dihydroprogesterone and tetrahydroprogesterone, on the expression and phosphorylation of glycogen synthase kinase-3 and the microtubule-associated protein tau in the rat cerebellum.
Journal: Developmental neurobiology 20070301
Title: Progesterone and its derivatives are neuroprotective agents in experimental diabetic neuropathy: a multimodal analysis.
Journal: Neuroscience 20070223
Title: Differential regulation of ionotropic glutamate receptors.
Journal: Biophysical journal 20070215
Title: Ethanol modulates the interaction of the endogenous neurosteroid allopregnanolone with the alpha1beta2gamma2L GABAA receptor.
Journal: Molecular pharmacology 20070201
Title: [A new aspect in the research on antiepileptic drugs].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070201
Title: The progesterone metabolite allopregnanolone potentiates GABA(A) receptor-mediated inhibition of 5-HT neuronal activity.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070115
Title: The anticonvulsant effects of allopregnanolone against amygdala-kindled seizures in female rats.
Journal: Neuroscience letters 20070110
Title: Steroid requirements for regulation of the alpha4 subunit of the GABA(A) receptor in an in vitro model.
Journal: Neuroscience letters 20070103
Title: Allopregnanolone reduces immobility in the forced swimming test and increases the firing rate of lateral septal neurons through actions on the GABAA receptor in the rat.
Journal: Journal of psychopharmacology (Oxford, England) 20070101
Title: Effects of neurosteroids on glucocorticoid receptor-mediated gene transcription in LMCAT cells--a possible interaction with psychotropic drugs.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070101
Title: Lack of enantiomeric specificity in the effects of anesthetic steroids on lipid bilayers.
Journal: Biochimica et biophysica acta 20070101
Title: Sex differences in steroid modulation of ethanol withdrawal in male and female rats.
Journal: The Journal of pharmacology and experimental therapeutics 20070101
Title: Drospirenone increases central and peripheral beta-endorphin in ovariectomized female rats.
Journal: Menopause (New York, N.Y.) 20070101
Title: Ganaxolone.
Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20070101
Title: [Neurosteroids and their function].
Journal: Casopis lekaru ceskych 20070101
Title: Progesterone derivatives increase expression of Krox-20 and Sox-10 in rat Schwann cells.
Journal: Journal of molecular neuroscience : MN 20070101
Title: A new, non-SSRI mechanism of action for Prozac.
Journal: Current topics in medicinal chemistry 20070101
Title: Circulating levels of pregnanolone isomers during the third trimester of human pregnancy.
Journal: The Journal of steroid biochemistry and molecular biology 20070101
Title: Early evolution of ionotropic GABA receptors and selective regimes acting on the mammalian-specific theta and epsilon subunits.
Journal: PloS one 20070101
Title: Neuroactive steroids modulate HPA axis activity and cerebral brain-derived neurotrophic factor (BDNF) protein levels in adult male rats.
Journal: Psychoneuroendocrinology 20070101
Title: Pseudo-epileptic seizures in children are not associated with enhanced plasma level of allopregnanolone.
Journal: Pharmacological reports : PR 20070101
Title: The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease.
Journal: Biological psychiatry 20061215
Title: Progesterone and progestins: effects on brain, allopregnanolone and beta-endorphin.
Journal: The Journal of steroid biochemistry and molecular biology 20061201
Title: Infusions of 5alpha-pregnan-3alpha-ol-20-one (3alpha,5alpha-THP) to the ventral tegmental area, but not the substantia nigra, enhance exploratory, anti-anxiety, social and sexual behaviours and concomitantly increase 3alpha,5alpha-THP concentrations in the hippocampus, diencephalon and cortex of ovariectomised oestrogen-primed rats.
Journal: Journal of neuroendocrinology 20061201
Title: Hypothalamic-pituitary-adrenal axis modulation of GABAergic neuroactive steroids influences ethanol sensitivity and drinking behavior.
Journal: Dialogues in clinical neuroscience 20061201
Title: Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites.
Journal: Nature 20061123
Title: Neurosteroid modulation of allopregnanolone and GABA effect on the GABA-A receptor.
Journal: Neuroscience 20061117
Title: The effect of gonadal hormones and gender on anxiety and emotional learning.
Journal: Hormones and behavior 20061101
Title: Oral progesterone decreases saccadic eye velocity and increases sedation in women.
Journal: Psychoneuroendocrinology 20061101
Title: Associations of histories of depression and PMDD diagnosis with allopregnanolone concentrations following the oral administration of micronized progesterone.
Journal: Psychoneuroendocrinology 20061101
Title: The anxiolytic effect of pregnancy in rats is reversed by finasteride.
Journal: Pharmacology, biochemistry, and behavior 20061101
Title: Neurosteroids as endogenous inhibitors of neuronal cell apoptosis in aging.
Journal: Annals of the New York Academy of Sciences 20061101
Title: Neurosteroids regulate mouse aggression induced by anabolic androgenic steroids.
Journal: Neuroreport 20061002
Title: Rapid inhibition of Ca2+ influx by neurosteroids in murine embryonic sensory neurones.
Journal: Cell calcium 20061001
Title: Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder.
Journal: Biological psychiatry 20061001
Title: Sensitivity to the locomotor-stimulant effects of ethanol and allopregnanolone: a quantitative trait locus study of common genetic influence.
Journal: Genes, brain, and behavior 20061001
Title: Effects of pregnanolone in rats discriminating cocaine.
Journal: Pharmacology, biochemistry, and behavior 20061001
Title: Progesterone and its metabolites 5-dihydroprogesterone and 5-3-tetrahydroprogesterone decrease LPS-induced NO release in the murine microglial cell line, BV-2.
Journal: Neuro endocrinology letters 20061001
Title: Mechanisms of modulation of pregnanolone on glycinergic response in cultured spinal dorsal horn neurons of rat.
Journal: Neuroscience 20060915
Title: Increased levels of pregnenolone and its neuroactive metabolite allopregnanolone in autopsied brain tissue from cirrhotic patients who died in hepatic coma.
Journal: Neurochemistry international 20060901
Title: Anticonvulsant action of allopregnanolone in immature rats.
Journal: Epilepsy research 20060801
Title: Efficacy and the discriminative stimulus effects of negative GABAA modulators, or inverse agonists, in diazepam-treated rhesus monkeys.
Journal: The Journal of pharmacology and experimental therapeutics 20060801
Title: Serum profiles of free and conjugated neuroactive pregnanolone isomers in nonpregnant women of fertile age.
Journal: The Journal of clinical endocrinology and metabolism 20060801
Title: Allopregnanolone concentration and mood--a bimodal association in postmenopausal women treated with oral progesterone.
Journal: Psychopharmacology 20060801
Title: Tapered progesterone withdrawal promotes long-term recovery following brain trauma.
Journal: Experimental neurology 20060801
Title: Increased neuroactive steroid concentrations in women with bipolar disorder or major depressive disorder.
Journal: Journal of clinical psychopharmacology 20060801
Title: Plastic neuronal changes in GABA(A) receptor gene expression induced by progesterone metabolites: in vitro molecular and functional studies.
Journal: Pharmacology, biochemistry, and behavior 20060801
Title: Olanzapine and fluoxetine administration and coadministration increase rat hippocampal pregnenolone, allopregnanolone and peripheral deoxycorticosterone: implications for therapeutic actions.
Journal: Pharmacology, biochemistry, and behavior 20060801
Title: Neurosteroid analogues. 11. Alternative ring system scaffolds: gamma-aminobutyric acid receptor modulation and anesthetic actions of benz[f]indenes.
Journal: Journal of medicinal chemistry 20060727
Title: The anticonvulsant effects of progesterone and its metabolites on amygdala-kindled seizures in male rats.
Journal: Brain research 20060726
Title: Neurosteroid modulation of respiratory rhythm in rats during the perinatal period.
Journal: The Journal of physiology 20060715
Title: Sigma1 receptor ligands and related neuroactive steroids interfere with the cocaine-induced state of memory.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060701
Title: Social isolation-induced increase in alpha and delta subunit gene expression is associated with a greater efficacy of ethanol on steroidogenesis and GABA receptor function.
Journal: Journal of neurochemistry 20060701
Title: Therapeutic potential of neurogenesis for prevention and recovery from Alzheimer's disease: allopregnanolone as a proof of concept neurogenic agent.
Journal: Current Alzheimer research 20060701
Title: Influence of ginsenoside Rb1 on brain neurosteroid during acute immobilization stress.
Journal: Archives of pharmacal research 20060701
Title: Ethnic differences in allopregnanolone concentrations in women during rest and following mental stress.
Journal: Psychophysiology 20060701
Title: Chronic intermittent ethanol exposure during adolescence reduces the effect of ethanol challenge on hippocampal allopregnanolone levels and Morris water maze task performance.
Journal: Alcohol (Fayetteville, N.Y.) 20060701
Title: Pharmacokinetics of progesterone and its metabolites allopregnanolone and pregnanolone after oral administration of low-dose progesterone.
Journal: Maturitas 20060620
Title: Lack of evidence of a role for the neurosteroid allopregnanolone in ethanol-induced reward and c-fos expression in DBA/2 mice.
Journal: Brain research 20060613
Title: Neurosteroids in nicotine and morphine dependence.
Journal: Psychopharmacology 20060601
Title: Neurosteroids, GABAA receptors, and ethanol dependence.
Journal: Psychopharmacology 20060601
Title: Pharmacokinetic and behavioral effects of allopregnanolone in healthy women.
Journal: Psychopharmacology 20060601
Title: Steroid withdrawal in the mouse results in anxiogenic effects of 3alpha,5beta-THP: a possible model of premenstrual dysphoric disorder.
Journal: Psychopharmacology 20060601
Title: 3alpha,5alpha-THP: a potential plasma neurosteroid biomarker in Alzheimer's disease and perhaps non-Alzheimer's dementia.
Journal: Psychopharmacology 20060601
Title: Moderate doses of ethanol fail to increase plasma levels of neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one-like immunoreactivity in healthy men and women.
Journal: Psychopharmacology 20060601
Title: Relevance of endogenous 3alpha-reduced neurosteroids to depression and antidepressant action.
Journal: Psychopharmacology 20060601
Title: Neurosteroids and cholinergic systems: implications for sleep and cognitive processes and potential role of age-related changes.
Journal: Psychopharmacology 20060601
Title: An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons.
Journal: Neurochemistry international 20060601
Title: Early postnatal stimulation alters pregnane neurosteroids in the hippocampus.
Journal: Psychopharmacology 20060601
Title: Enantiomers of neuroactive steroids support a specific interaction with the GABA-C receptor as the mechanism of steroid action.
Journal: Molecular pharmacology 20060601
Title: Progesterone's effects to reduce anxiety behavior of aged mice do not require actions via intracellular progestin receptors.
Journal: Psychopharmacology 20060601
Title: Neonatal neurosteroid administration results in development-specific alterations in prepulse inhibition and locomotor activity: neurosteroids alter prepulse inhibition and locomotor activity.
Journal: Psychopharmacology 20060601
Title: Effects of some neurosteroids injected into some brain areas of WAG/Rij rats, an animal model of generalized absence epilepsy.
Journal: Neuropharmacology 20060601
Title: Activity of B-nor analogues of neurosteroids on the GABA(A) receptor in primary neuronal cultures.
Journal: Journal of medicinal chemistry 20060601
Title: Sex-dimorphic effects of progesterone and its reduced metabolites on gene expression of myelin proteins by rat Schwann cells.
Journal: Journal of the peripheral nervous system : JPNS 20060601
Title: Tolerance development to Morris water maze test impairments induced by acute allopregnanolone.
Journal: Neuroscience 20060512
Title: Impaired reduction of enhanced levels of dehydroepiandrosterone by oral dexamethasone in anorexia nervosa.
Journal: Psychoneuroendocrinology 20060501
Title: Allopregnanolone produces hyperphagia by reducing neophobia without altering food palatability.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060501
Title: Observational study on the stability of the psychological status during normal pregnancy and increased blood levels of neuroactive steroids with GABA-A receptor agonist activity.
Journal: Psychoneuroendocrinology 20060501
Title: Allopregnanolone and ganaxolone increase the firing activity of dorsal raphe nucleus serotonergic neurons in female rats.
Journal: The international journal of neuropsychopharmacology 20060401
Title: Injury elicited increase in spinal cord neurosteroid content analyzed by gas chromatography mass spectrometry.
Journal: Endocrinology 20060401
Title: Allopregnanolone, a progesterone metabolite, is more effective than progesterone in reducing cortical infarct volume after transient middle cerebral artery occlusion.
Journal: Annals of emergency medicine 20060401
Title: Stiripentol, a putative antiepileptic drug, enhances the duration of opening of GABA-A receptor channels.
Journal: Epilepsia 20060401
Title: Rats bred for high versus low anxiety responses neonatally demonstrate increases in lordosis, pacing behavior, and midbrain 3 alpha, 5 alpha-THP levels as adults.
Journal: Behavioral neuroscience 20060401
Title: GABA(A) receptor changes in acute allopregnanolone tolerance.
Journal: European journal of pharmacology 20060327
Title: Differential effect of kinase A and C blockers on lordosis facilitation by progesterone and its metabolites in ovariectomized estrogen-primed rats.
Journal: Hormones and behavior 20060301
Title: Pharmacogenetics of antipsychotic therapy: pivotal research issues and the prospects for clinical implementation.
Journal: Dialogues in clinical neuroscience 20060301
Title: Effects of neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one on ethanol-mediated paired-pulse depression of population spikes in the CA1 region of rat hippocampal slices.
Journal: Neuroscience letters 20060206
Title: Syntheses of 19-[O-(carboxymethyl)oxime] haptens of epipregnanolone and pregnanolone.
Journal: Steroids 20060201
Title: 3alpha-OL-5-beta-pregnan-20-one hemisuccinate, a steroidal low-affinity NMDA receptor antagonist improves clinical rating scores in a rabbit multiple infarct ischemia model: synergism with tissue plasminogen activator.
Journal: Experimental neurology 20060201
Title: Selected line difference in sensitivity to a GABAergic neurosteroid during ethanol withdrawal.
Journal: Genes, brain, and behavior 20060201
Title: Understanding how the brain perceives alcohol: neurobiological basis of ethanol discrimination.
Journal: Alcoholism, clinical and experimental research 20060201
Title: Preclinical analyses of the therapeutic potential of allopregnanolone to promote neurogenesis in vitro and in vivo in transgenic mouse model of Alzheimer's disease.
Journal: Current Alzheimer research 20060201
Title: Histories of depression, allopregnanolone responses to stress, and premenstrual symptoms in women.
Journal: Biological psychology 20060101
Title: Analysis of derivatised steroids by matrix-assisted laser desorption/ionisation and post-source decay mass spectrometry.
Journal: Steroids 20060101
Title: Circulating neuroactive C21- and C19-steroids in young men before and after ejaculation.
Journal: Physiological research 20060101
Title: Action of two neuroactive steroids against motor seizures induced by pentetrazol in rats during ontogeny.
Journal: Physiological research 20060101
Title: Synthesis of 3alpha-hydroxy-21-(1'-imidazolyl)-3beta-methoxyl-methyl-5alpha-pregnan-20-one via lithium imidazole with 17alpha-acetylbromopregnanone.
Journal: Steroids 20060101
Title: 3alpha-hydroxy-5alpha-pregnan-20-one in the midbrain ventral tegmental area mediates social, sexual, and affective behaviors.
Journal: Neuroscience 20060101
Title: Peripheral-type benzodiazepine receptor in neurosteroid biosynthesis, neuropathology and neurological disorders.
Journal: Neuroscience 20060101
Title: Impact of epsilon and theta subunits on pharmacological properties of alpha3beta1 GABAA receptors expressed in Xenopus oocytes.
Journal: BMC pharmacology 20060101
Title: Anti-apoptotic effects of allopregnanolone on P19 neurons.
Journal: The European journal of neuroscience 20060101
Title: Perinatal allopregnanolone influences prefrontal cortex structure, connectivity and behavior in adult rats.
Journal: Neuroscience 20060101
Title: Metformin administration modulates neurosteroids secretion in non-obese amenorrhoic patients with polycystic ovary syndrome.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20060101
Title: Prediction models for insulin resistance in girls with premature adrenarche. The premature adrenarche insulin resistance score: PAIR score.
Journal: Hormone research 20060101
Title: Effect of tibolone administration on central and peripheral levels of allopregnanolone and beta-endorphin in female rats.
Journal: Menopause (New York, N.Y.) 20060101
Title: Hypoxia potentiates endotoxin-induced allopregnanolone concentrations in the newborn brain.
Journal: Biology of the neonate 20060101
Title: Biosynthesis and organizing action of neurosteroids in the developing Purkinje cell.
Journal: Cerebellum (London, England) 20060101
Title: Progesterone and medroxyprogesterone acetate effects on central and peripheral allopregnanolone and beta-endorphin levels.
Journal: Neuroendocrinology 20060101
Title: Relationship between omega-3 fatty acids and plasma neuroactive steroids in alcoholism, depression and controls.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20060101
Title: Progestin concentrations are increased following paced mating in midbrain, hippocampus, diencephalon, and cortex of rats in behavioral estrus, but only in midbrain of diestrous rats.
Journal: Neuroendocrinology 20060101
Title: Stress in pregnancy activates neurosteroid production in the fetal brain.
Journal: Neuroendocrinology 20060101
Title: Anticonvulsant action of three neurosteroids against cortical epileptic afterdischarges in immature rats.
Journal: Brain research bulletin 20051230
Title: Allopregnanolone treatment, both as a single injection or repetitively, delays demyelination and enhances survival of Niemann-Pick C mice.
Journal: Journal of neuroscience research 20051215
Title: The anxiolytic etifoxine activates the peripheral benzodiazepine receptor and increases the neurosteroid levels in rat brain.
Journal: Pharmacology, biochemistry, and behavior 20051201
Title: The intrahippocampal administration of the neurosteroid allopregnanolone blocks the audiogenic seizures induced by nicotine.
Journal: Brain research 20051116
Title: Low concentrations of neuroactive steroids alter kinetics of [3H]ifenprodil binding to the NMDA receptor in rat frontal cortex.
Journal: British journal of pharmacology 20051101
Title: The importance of 'awareness' for understanding fetal pain.
Journal: Brain research. Brain research reviews 20051101
Title: 3alpha-reduced neuroactive steroids and their precursors during pregnancy and the postpartum period.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20051101
Title: [Effects of morphine dependence on the levels of neurosteroids in rat brain].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20051101
Title: Intrahippocampal nicotine and neurosteroids effects on the anxiety-like behaviour in voluntary and chronic alcohol-drinking rats.
Journal: Behavioural brain research 20051014
Title: Short-term steroid treatment increases delta GABAA receptor subunit expression in rat CA1 hippocampus: pharmacological and behavioral effects.
Journal: Neuropharmacology 20051001
Title: The effect of a low dose of alcohol on allopregnanolone serum concentrations across the menstrual cycle in women with severe premenstrual syndrome and controls.
Journal: Psychoneuroendocrinology 20051001
Title: Negative GABA(A) modulators attenuate the discriminative stimulus effects of benzodiazepines and the neuroactive steroid pregnanolone in rhesus monkeys.
Journal: Psychopharmacology 20051001
Title: Evaluation of O(3alpha)-, O(21)-di-(N(1)-methyloxycarbonyl-2, 4-dioxo-5-fluoropyrimidinyl) 17alpha-hydroxy-5beta-pregnan-20-one as a novel potential antiangiogenic codrug.
Journal: Journal of enzyme inhibition and medicinal chemistry 20051001
Title: Interaction of cocaine with positive GABAA modulators on the repeated acquisition and performance of response sequences in rats.
Journal: Psychopharmacology 20050901
Title: Low serum allopregnanolone levels in girls with precocious pubarche.
Journal: Steroids 20050901
Title: High affinity, heterogeneous displacement of [3H]EBOB binding to cerebellar GABA A receptors by neurosteroids and GABA agonists.
Journal: Neuropharmacology 20050901
Title: Neurosteroids exhibit differential effects on mIPSCs recorded from normal and seizure prone rats.
Journal: Journal of neurophysiology 20050901
Title: Inhibiting biosynthesis and/or metabolism of progestins in the ventral tegmental area attenuates lordosis of rats in behavioural oestrus.
Journal: Journal of neuroendocrinology 20050901
Title: Alphaxalone and epiallopregnanolone in rats trained to discriminate ethanol.
Journal: Alcoholism, clinical and experimental research 20050901
Title: Neurosteroid modulators of GABA(A) receptors differentially modulate Ethanol intake patterns in male C57BL/6J mice.
Journal: Alcoholism, clinical and experimental research 20050901
Title: Effects of intrahippocampal nicotine and neurosteroid administration on withdrawal in voluntary and chronic alcohol-drinking rats.
Journal: Alcoholism, clinical and experimental research 20050901
Title: Characterization of the discriminative stimulus effects of the neuroactive steroid pregnanolone in DBA/2J and C57BL/6J inbred mice.
Journal: The Journal of pharmacology and experimental therapeutics 20050801
Title: Dehydroepiandrosterone sulfate and allopregnanolone directly stimulate catecholamine production via induction of tyrosine hydroxylase and secretion by affecting actin polymerization.
Journal: Endocrinology 20050801
Title: Distinct patterns of expression and regulation of GABA receptors containing the delta subunit in cerebellar granule and hippocampal neurons.
Journal: Journal of neurochemistry 20050801
Title: Estrogen-priming can enhance progesterone's anti-seizure effects in part by increasing hippocampal levels of allopregnanolone.
Journal: Pharmacology, biochemistry, and behavior 20050801
Title: [Stress and sleep/emotional disorder: possible involvement of neurosteroid allopregnanolone].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20050801
Title: Treatment with and withdrawal from finasteride alter ethanol intake patterns in male C57BL/6J mice: potential role of endogenous neurosteroids?
Journal: Alcohol (Fayetteville, N.Y.) 20050801
Title: Discriminative stimulus effects of 5.6 mg/kg pregnanolone in DBA/2J and C57BL/6J inbred mice.
Journal: Alcohol (Fayetteville, N.Y.) 20050801
Title: [Effects of pregnanolone on spontaneous firing of pain nucleus of habenula in rats].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20050801
Title: Allopregnanolone and pregnanolone are produced by the human corpus luteum.
Journal: Molecular and cellular endocrinology 20050715
Title: Termination of pseudopregnancy in the rat alters the response to progesterone, chlordiazepoxide, and MK-801 in the elevated plus-maze.
Journal: Psychopharmacology 20050701
Title: Evaluation of GABAergic neuroactive steroid 3alpha-hydroxy-5alpha-pregnane-20-one as a neurobiological substrate for the anti-anxiety effect of ethanol in rats.
Journal: Psychopharmacology 20050701
Title: Altered profiles of serum neuroactive steroids in premenopausal women treated for alcohol addiction.
Journal: Steroids 20050701
Title: Nanomolar allopregnanolone potentiates rat cerebellar GABAA receptors.
Journal: Neuroscience letters 20050701
Title: Epipregnanolone and a novel synthetic neuroactive steroid reduce alcohol self-administration in rats.
Journal: Pharmacology, biochemistry, and behavior 20050701
Title: Increased brain concentrations of a neuroinhibitory steroid in human hepatic encephalopathy.
Journal: Annals of neurology 20050701
Title: Endogenous gamma-aminobutyric acid (GABA)(A) receptor active neurosteroids and the sedative/hypnotic action of gamma-hydroxybutyric acid (GHB): a study in GHB-S (sensitive) and GHB-R (resistant) rat lines.
Journal: Neuropharmacology 20050701
Title: Neuroactive steroids and ethanol.
Journal: Alcoholism, clinical and experimental research 20050701
Title: Two new pregnanone derivatives with strong cytotoxic activity from Pachysandra axillaris.
Journal: Chemistry & biodiversity 20050701
Title: Plasma concentrations of anxiolytic neuroactive steroids in men with panic disorder.
Journal: Psychiatry research 20050630
Title: Reinstatement of serum pregnanolone isomers and progesterone during alcohol detoxification therapy in premenopausal women.
Journal: Alcoholism, clinical and experimental research 20050601
Title: The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050511
Title: Cortical 3 alpha-hydroxy-5 alpha-pregnan-20-one levels after acute administration of Delta 9-tetrahydrocannabinol, cocaine and morphine.
Journal: Psychopharmacology 20050501
Title: Differences in affective behaviors and hippocampal allopregnanolone levels in adult rats of lines selectively bred for infantile vocalizations.
Journal: Behavioural brain research 20050430
Title: Neurosteroid analogues. 10. The effect of methyl group substitution at the C-6 and C-7 positions on the GABA modulatory and anesthetic actions of (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.
Journal: Journal of medicinal chemistry 20050421
Title: Intracellular oxidation of allopregnanolone by human brain type 10 17beta-hydroxysteroid dehydrogenase.
Journal: Brain research 20050408
Title: Isoallopregnanolone; an antagonist to the anaesthetic effect of allopregnanolone in male rats.
Journal: European journal of pharmacology 20050404
Title: Combined discriminative stimulus effects of midazolam with other positive GABAA modulators and GABAA receptor agonists in rhesus monkeys.
Journal: Psychopharmacology 20050401
Title: New evidence that both T-type calcium channels and GABAA channels are responsible for the potent peripheral analgesic effects of 5alpha-reduced neuroactive steroids.
Journal: Pain 20050401
Title: Reversal of caffeine-induced anxiety by neurosteroid 3-alpha-hydroxy-5-alpha-pregnane-20-one in rats.
Journal: Neuropharmacology 20050401
Title: Effect of dehydroepiandrosterone on central and peripheral levels of allopregnanolone and beta-endorphin.
Journal: Fertility and sterility 20050401
Title: Rapid non-genomic effect of glucocorticoid metabolites and neurosteroids on the gamma-aminobutyric acid-A receptor.
Journal: The European journal of neuroscience 20050401
Title: Progesterone's 5 alpha-reduced metabolite, 3 alpha,5 alpha-THP, mediates lateral displacement of hamsters.
Journal: Brain research 20050315
Title: In the ventral tegmental area picrotoxin blocks FGIN 1-27-induced increases in sexual behavior of rats and hamsters.
Journal: Psychopharmacology 20050301
Title: Antidepressant-like actions of intra-accumbens infusions of allopregnanolone in ovariectomized Wistar rats.
Journal: Pharmacology, biochemistry, and behavior 20050301
Title: Tibolone, transdermal estradiol or oral estrogen-progestin therapies: effects on circulating allopregnanolone, cortisol and dehydroepiandrosterone levels.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20050301
Title: Relationship between allopregnanolone and negative mood in postmenopausal women taking sequential hormone replacement therapy with vaginal progesterone.
Journal: Psychoneuroendocrinology 20050201
Title: Interaction between allopregnanolone and pregnenolone sulfate in modulating GABA-mediated synaptic currents in neurons from the rat medial preoptic nucleus.
Journal: Brain research 20050201
Title: Anesthetic effects of progesterone are undiminished in progesterone receptor knockout mice.
Journal: Brain research 20050201
Title: Changes in bovine luteal progesterone metabolism in response to exogenous prostaglandin F(2alpha).
Journal: Domestic animal endocrinology 20050201
Title: Post-ictal circulating levels of allopregnanolone in children with partial or generalized seizures.
Journal: Epilepsy research 20050201
Title: The effect of dehydroepiandrosterone sulfate and allopregnanolone sulfate on the binding of [(3)H]ifenprodil to the N-methyl-d-aspartate receptor in rat frontal cortex membrane.
Journal: The Journal of steroid biochemistry and molecular biology 20050201
Title: Termination of pseudopregnancy in the rat produces an anxiogenic-like response that is associated with an increase in benzodiazepine receptor binding density and a decrease in GABA-stimulated chloride influx in the hippocampus.
Journal: Brain research bulletin 20050130
Title: Estradiol and the addition of progesterone increase the sensitivity to a neurosteroid in postmenopausal women.
Journal: Psychoneuroendocrinology 20050101
Title: Neuroactive pregnanolone isomers during pregnancy.
Journal: The Journal of clinical endocrinology and metabolism 20050101
Title: Anxiolytic activity of progesterone in progesterone receptor knockout mice.
Journal: Neuropharmacology 20050101
Title: Electrophysiological effects of allopregnanolone in rats with a history of ethanol exposure.
Journal: Alcoholism, clinical and experimental research 20050101
Title: The neurosteroids progesterone and allopregnanolone reduce cell death, gliosis, and functional deficits after traumatic brain injury in rats.
Journal: Journal of neurotrauma 20050101
Title: Behavioral sensitization to ethanol is modulated by environmental conditions, but is not associated with cross-sensitization to allopregnanolone or pentobarbital in DBA/2J mice.
Journal: Neuroscience 20050101
Title: [The role of neurosteroids in the central nervous system function].
Journal: Przeglad lekarski 20050101
Title: 3alpha,5alpha-Tetrahydroprogesterone (allopregnanolone) and gamma-aminobutyric acid: autocrine/paracrine interactions in the control of neonatal PSA-NCAM+ progenitor proliferation.
Journal: Journal of neuroscience research 20041215
Title: Discriminative stimulus effects of ethanol in rats using a three-choice ethanol-midazolam-water discrimination.
Journal: Behavioural pharmacology 20041201
Title: Role of neurosteroids in catamenial epilepsy.
Journal: Epilepsy research 20041201
Title: Synergistic interaction between ketoconazole and several antidepressant drugs with allopregnanolone treatments in ovariectomized Wistar rats forced to swim.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20041201
Title: Disadaptive disorders in women: allopregnanolone, a sensitive steroid.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20041201
Title: Role of alcohol consumption in escalation to violence.
Journal: Annals of the New York Academy of Sciences 20041201
Title: Progesterone attenuates corticotropin-releasing factor-enhanced but not fear-potentiated startle via the activity of its neuroactive metabolite, allopregnanolone.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110
Title: Effects of PhD examination stress on allopregnanolone and cortisol plasma levels and peripheral benzodiazepine receptor density.
Journal: Psychoneuroendocrinology 20041101
Title: Niemann pick type C disease as a model for defects in neurosteroidogenesis.
Journal: Endocrine research 20041101
Title: Increased allopregnanolone levels in the fetal sheep brain following umbilical cord occlusion.
Journal: The Journal of physiology 20041015
Title: Role of allopregnanolone on cerebellar granule cells neurogenesis.
Journal: Brain research. Developmental brain research 20041015
Title: Essentiality of central GABAergic neuroactive steroid allopregnanolone for anticonvulsant action of fluoxetine against pentylenetetrazole-induced seizures in mice.
Journal: Brain research 20041008
Title: Allopregnanolone does not influence ethanol-induced conditioned place preference in DBA/2J mice.
Journal: Psychopharmacology 20041001
Title: Dynamic aspects of acute tolerance to allopregnanolone evaluated using anaesthesia threshold in male rats.
Journal: British journal of anaesthesia 20041001
Title: Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury.
Journal: Experimental neurology 20041001
Title: Modulation of GABA(A) receptor gene expression by allopregnanolone and ethanol.
Journal: European journal of pharmacology 20041001
Title: PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators.
Journal: Toxicology and applied pharmacology 20040915
Title: Influence of 17beta-estradiol on the synthesis of reduced neurosteroids in the brain (in vivo) and in glioma cells (in vitro): possible relevance to mental disorders in women.
Journal: Brain research 20040910
Title: Role of neuroactive steroid allopregnanolone in antipsychotic-like action of olanzapine in rodents.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040901
Title: Impact of neuropathic pain on the gene expression and activity of cytochrome P450side-chain-cleavage in sensory neural networks.
Journal: Cellular and molecular life sciences : CMLS 20040901
Title: Fetal alcohol exposure alters neurosteroid levels in the developing rat brain.
Journal: Journal of neurochemistry 20040901
Title: 3beta-20beta-dihydroxy-5alpha-pregnane (UC1011) antagonism of the GABA potentiation and the learning impairment induced in rats by allopregnanolone.
Journal: The European journal of neuroscience 20040901
Title: Pharmacology of catamenial epilepsy.
Journal: Methods and findings in experimental and clinical pharmacology 20040901
Title: [Pregnanolone effects on the blood pressure of stress-induced hypertension in rats].
Journal: Sheng li xue bao : [Acta physiologica Sinica] 20040825
Title: Long-term treatment with clozapine does not affect morning circulating levels of allopregnanolone and THDOC in patients with schizophrenia: a preliminary study.
Journal: Journal of clinical psychopharmacology 20040801
Title: Ethanol-induced elevation of 3 alpha-hydroxy-5 alpha-pregnan-20-one does not modulate motor incoordination in rats.
Journal: Alcoholism, clinical and experimental research 20040801
Title: Slow actions of neuroactive steroids at GABAA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040728
Title: Brain steroidogenesis mediates ethanol modulation of GABAA receptor activity in rat hippocampus.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040721
Title: Anticonvulsant activity of progesterone and neurosteroids in progesterone receptor knockout mice.
Journal: The Journal of pharmacology and experimental therapeutics 20040701
Title: Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone.
Journal: Nature medicine 20040701
Title: Insight into the mechanism of action of neuroactive steroids.
Journal: Molecular pharmacology 20040701
Title: Dipole potential and head-group spacing are determinants for the membrane partitioning of pregnanolone.
Journal: Molecular pharmacology 20040701
Title: Modulation of the firing activity of female dorsal raphe nucleus serotonergic neurons by neuroactive steroids.
Journal: The Journal of endocrinology 20040701
Title: Allopregnanolone in the brain and blood after disruption of the hypothalamic-pituitary-adrenal axis in fetal sheep.
Journal: The Journal of endocrinology 20040701
Title: Brain on steroids resists neurodegeneration.
Journal: Nature medicine 20040701
Title: Allopregnanolone analogs that positively modulate GABA receptors protect against partial seizures induced by 6-Hz electrical stimulation in mice.
Journal: Epilepsia 20040701
Title: Progestins' actions in the VTA to facilitate lordosis involve dopamine-like type 1 and 2 receptors.
Journal: Pharmacology, biochemistry, and behavior 20040701
Title: Interaction of chronic ethanol exposure and finasteride: sex and strain differences.
Journal: Pharmacology, biochemistry, and behavior 20040701
Title: Sexually dimorphic effects of postnatal allopregnanolone on the development of anxiety behavior after early deprivation.
Journal: Pharmacology, biochemistry, and behavior 20040701
Title: 3alpha,5alpha-THP mediates progestins' effects to protect against adrenalectomy-induced cell death in the dentate gyrus of female and male rats.
Journal: Pharmacology, biochemistry, and behavior 20040701
Title: Hippocampal 3alpha,5alpha-THP may alter depressive behavior of pregnant and lactating rats.
Journal: Pharmacology, biochemistry, and behavior 20040701
Title: Neonatal neurosteroid administration alters parvalbumin expression and neuron number in medial dorsal thalamus of adult rats.
Journal: Brain research 20040625
Title: Panic disorder in menopause: a case control study.
Journal: Maturitas 20040615
Title: Pharmacological plasticity of GABA(A) receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy.
Journal: The Journal of physiology 20040601
Title: Acute neurosteroid modulation and subunit isolation of the gamma-aminobutyric acidA receptor in the bullfrog, Rana catesbeiana.
Journal: Journal of molecular endocrinology 20040601
Title: Discriminative stimulus effects of ethanol in mice lacking the gamma-aminobutyric acid type A receptor delta subunit.
Journal: Alcoholism, clinical and experimental research 20040601
Title: Protective effect of pregnanolone against lipoperoxidation and free radicals generation induced in hypothalamus of ovariectomized rats submitted to CO2 exposure.
Journal: Pharmacology, biochemistry, and behavior 20040601
Title: Sites of positive allosteric modulation by neurosteroids on ionotropic gamma-aminobutyric acid receptor subunits.
Journal: FEBS letters 20040521
Title: Teaching resources. Regulation of GABA receptor activity by neurosteroids and phosphorylation.
Journal: Science's STKE : signal transduction knowledge environment 20040518
Title: Identification of 3beta,5beta-tetrahydroprogesterone, a progesterone metabolite, and its stimulatory action on preoptic neurons in the avian brain.
Journal: Brain research 20040508
Title: The interaction of anaesthetic steroids with recombinant glycine and GABAA receptors.
Journal: British journal of anaesthesia 20040501
Title: Chronic prenatal ethanol exposure alters hippocampal GABA(A) receptors and impairs spatial learning in the guinea pig.
Journal: Behavioural brain research 20040402
Title: Administration of progesterone produces mild sedative-like effects in men and women.
Journal: Psychoneuroendocrinology 20040401
Title: Effects of pregnanolone alone and in combination with other positive GABAA modulators on complex behavior in rats.
Journal: Psychopharmacology 20040401
Title: Alcohol intoxication increases allopregnanolone levels in male adolescent humans.
Journal: Psychopharmacology 20040301
Title: Estradiol and testosterone modulate the anesthetic action of the GABA-A agonist THIP, but not of the neurosteroid 3alpha,5beta-pregnanolone in the rat.
Journal: Psychopharmacology 20040301
Title: Chronic intermittent ethanol (CIE) administration in rats decreases levels of neurosteroids in hippocampus, accompanied by altered behavioral responses to neurosteroids and memory function.
Journal: Neuropharmacology 20040301
Title: Conjugated equine estrogens reverse the effects of aging on central and peripheral allopregnanolone and beta-endorphin levels in female rats.
Journal: Fertility and sterility 20040301
Title: Psychological effect of the oral contraceptive formulation containing 3 mg of drospirenone plus 30 microg of ethinyl estradiol.
Journal: Fertility and sterility 20040301
Title: Synthesis of [19- 2H3]-analogs of dehydroepiandrosterone and pregnenolone and their sulfates.
Journal: Steroids 20040301
Title: Chronic antidepressants reverse cerebrocortical allopregnanolone decline in the olfactory-bulbectomized rat.
Journal: European journal of pharmacology 20040213
Title: The neuroactive steroid 3-alpha-ol-5-beta-pregnan-20-one hemisuccinate, a selective NMDA receptor antagonist improves behavioral performance following spinal cord ischemia.
Journal: Brain research 20040206
Title: Cytochrome P450 2D catalyze steroid 21-hydroxylation in the brain.
Journal: Endocrinology 20040201
Title: Neuroactive steroid interactions with voltage-dependent anion channels: lack of relationship to GABA(A) receptor modulation and anesthesia.
Journal: The Journal of pharmacology and experimental therapeutics 20040201
Title: Elevated levels of some neuroactive progesterone metabolites, particularly isopregnanolone, in women with chronic fatigue syndrome.
Journal: Psychoneuroendocrinology 20040201
Title: Studies on the mechanisms of action of picrotoxin, quercetin and pregnanolone at the GABA rho 1 receptor.
Journal: British journal of pharmacology 20040201
Title: The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches.
Journal: Pharmacology & therapeutics 20040201
Title: Adrenal response to adrenocorticotropic hormone stimulation in patients with premenstrual syndrome.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040201
Title: Production of 5alpha-reduced neurosteroids is developmentally regulated and shapes GABA(A) miniature IPSCs in lamina II of the spinal cord.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040128
Title: Ethanol-induced increases in neuroactive steroids in the rat brain and plasma are absent in adrenalectomized and gonadectomized rats.
Journal: European journal of pharmacology 20040126
Title: Derivation of preliminary three-dimensional pharmacophoric maps for chemically diverse intravenous general anaesthetics.
Journal: British journal of anaesthesia 20040101
Title: Allopregnanolone and progesterone decrease cell death and cognitive deficits after a contusion of the rat pre-frontal cortex.
Journal: Neuroscience 20040101
Title: Potentiated modulation of pregnolone on GABAA receptors in behaviorally stressed borderline-hypertensive rats.
Journal: Biological & pharmaceutical bulletin 20040101
Title: The implications of 7-dehydrosterol-7-reductase deficiency (Smith-Lemli-Opitz syndrome) to neurosteroid production.
Journal: Steroids 20040101
Title: The nitric oxide pathway participates in estrous behavior induced by progesterone and some of its ring A-reduced metabolites.
Journal: Hormones and behavior 20040101
Title: Sex differences in the effect of ethanol injection and consumption on brain allopregnanolone levels in C57BL/6 mice.
Journal: Neuroscience 20040101
Title: Neuroactive steroids are not affected by panic induction with 50 microg cholecystokinin-tetrapeptide (CCK-4) in healthy volunteers.
Journal: Journal of psychiatric research 20040101
Title: Reduced progesterone metabolites protect rat hippocampal neurones from kainic acid excitotoxicity in vivo.
Journal: Journal of neuroendocrinology 20040101
Title: Allopregnanolone, a progesterone metabolite, enhances behavioral recovery and decreases neuronal loss after traumatic brain injury.
Journal: Restorative neurology and neuroscience 20040101
Title: Plasma concentrations of anxiolytic neurosteroids in men with normal anxiety scores: a correlation analysis.
Journal: Neuropsychobiology 20040101
Title: Ovariectomy and estradiol replacement therapy alters the adenine nucleotide hydrolysis in rat blood serum.
Journal: Thrombosis research 20040101
Title: Brain neurosteroids in gender-related aggression induced by social isolation.
Journal: Critical reviews in neurobiology 20040101
Title: [Determination of neurosteroids in rat brain by gas chromatography/mass spectrometry].
Journal: Se pu = Chinese journal of chromatography 20040101
Title: Neurosteroid analogues. 9. Conformationally constrained pregnanes: structure-activity studies of 13,24-cyclo-18,21-dinorcholane analogues of the GABA modulatory and anesthetic steroids (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.
Journal: Journal of medicinal chemistry 20031204
Title: Circulating levels of neuroactive steroids in patients with binge eating disorder: a comparison with nonobese healthy controls and non-binge eating obese subjects.
Journal: The International journal of eating disorders 20031201
Title: Impairments in spatial learning and memory: ethanol, allopregnanolone, and the hippocampus.
Journal: Brain research. Brain research reviews 20031201
Title: Neurosteroid consumption has anxiolytic effects in mice.
Journal: Pharmacology, biochemistry, and behavior 20031201
Title: Conditional regulation of neurosteroid sensitivity of GABAA receptors.
Journal: Annals of the New York Academy of Sciences 20031201
Title: Pathogenesis in menstrual cycle-linked CNS disorders.
Journal: Annals of the New York Academy of Sciences 20031201
Title: The contraceptive agent Provera enhances GABA(A) receptor-mediated inhibitory neurotransmission in the rat hippocampus: evidence for endogenous neurosteroids?
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031105
Title: Neurosteroids in rat brain: extraction, isolation, and analysis by nanoscale liquid chromatography-electrospray mass spectrometry.
Journal: Analytical chemistry 20031101
Title: Vaginal administration of allopregnanolone to postmenopausal women undergoing estrogen replacement therapy: preliminary results.
Journal: Maturitas 20031020
Title: 5alpha-reduced C21 steroids are substrates for human cytochrome P450c17.
Journal: Archives of biochemistry and biophysics 20031015
Title: Brain neurosteroid changes after paroxetine administration in mice.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20031001
Title: Neurosteroids alter gamma-aminobutyric acid postsynaptic currents in gonadotropin-releasing hormone neurons: a possible mechanism for direct steroidal control.
Journal: Endocrinology 20031001
Title: Dehydroepiandrosterone with other neurosteroids preserve neuronal mitochondria from calcium overload.
Journal: The Journal of steroid biochemistry and molecular biology 20031001
Title: Steroid-sensitive GABAA receptors in the fetal sheep brain.
Journal: Neuropharmacology 20030901
Title: Acylated-oxypregnane glycosides from the roots of Araujia sericifera.
Journal: Chemical & pharmaceutical bulletin 20030901
Title: Catamenial epilepsy: pathophysiology, diagnosis, and management.
Journal: Neurology 20030901
Title: Allopregnanolone-stimulated GABA-mediated chloride ion flux is inhibited by 3beta-hydroxy-5alpha-pregnan-20-one (isoallopregnanolone).
Journal: Brain research 20030822
Title: Structure-activity relationships in carboxamide derivatives based on the targeted delivery of radionuclides and boron atoms by means of peripheral benzodiazepine receptor ligands.
Journal: Journal of medicinal chemistry 20030814
Title: Neuroactive steroid 3 alpha-hydroxy-5 alpha-pregnan-20-one modulates ethanol-induced loss of righting reflex in rats.
Journal: Brain research 20030808
Title: Protective efficacy of neuroactive steroids against cocaine kindled-seizures in mice.
Journal: European journal of pharmacology 20030808
Title: Progesterone and its metabolites increase myelin basic protein expression in organotypic slice cultures of rat cerebellum.
Journal: Journal of neurochemistry 20030801
Title: Modulation of GABAA receptors and neuropeptide secretion by the neurosteroid allopregnanolone in posterior and intermediate pituitary.
Journal: Pharmacology & toxicology 20030801
Title: The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway.
Journal: The Journal of clinical endocrinology and metabolism 20030801
Title: Comparison of reinstatement of ethanol- and sucrose-seeking by conditioned stimuli and priming injections of allopregnanolone after extinction in rats.
Journal: Psychopharmacology 20030701
Title: Inhibition of NMDA-induced striatal dopamine release and behavioral activation by the neuroactive steroid 3alpha-hydroxy-5beta-pregnan-20-one hemisuccinate.
Journal: Journal of neurochemistry 20030701
Title: Long-term social isolation enhances picrotoxin seizure susceptibility in mice: up-regulatory role of endogenous brain allopregnanolone in GABAergic systems.
Journal: Pharmacology, biochemistry, and behavior 20030701
Title: Region-specific dysregulation of allopregnanolone brain content in the olfactory bulbectomized rat model of depression.
Journal: Brain research 20030620
Title: Changes in 5alpha-pregnane steroids and neurosteroidogenic enzyme expression in the perinatal sheep.
Journal: Pediatric research 20030601
Title: Alcohol intoxication increases allopregnanolone levels in female adolescent humans.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030601
Title: Neurocognitive functioning in subjects with eating disorders: the influence of neuroactive steroids.
Journal: Biological psychiatry 20030515
Title: Deletion of GABAA receptor alpha 1 subunit-containing receptors alters responses to ethanol and other anesthetics.
Journal: The Journal of pharmacology and experimental therapeutics 20030501
Title: The role of GABAB receptors in the discriminative stimulus effects of gamma-hydroxybutyrate in rats: time course and antagonism studies.
Journal: The Journal of pharmacology and experimental therapeutics 20030501
Title: Anxiogenic effects of neurosteroid exposure: sex differences and altered GABAA receptor pharmacology in adult rats.
Journal: The Journal of pharmacology and experimental therapeutics 20030501
Title: GABA(A) receptor active steroids are altered in epilepsy patients with tuberous sclerosis.
Journal: Journal of neurology, neurosurgery, and psychiatry 20030501
Title: Anti-conflict-like actions of intralateral septal infusions of allopregnanolone in Wistar rats.
Journal: Pharmacology, biochemistry, and behavior 20030501
Title: Comparison of the effects of allopregnanolone with direct GABAergic agonists on ethanol self-administration with and without concurrently available sucrose.
Journal: Alcohol (Fayetteville, N.Y.) 20030501
Title: Photoaffinity labeling with a neuroactive steroid analogue. 6-azi-pregnanolone labels voltage-dependent anion channel-1 in rat brain.
Journal: The Journal of biological chemistry 20030411
Title: Neurosteroid regulation of oxytocin and vasopressin release from the rat supraoptic nucleus.
Journal: The Journal of physiology 20030401
Title: Neurosteroid effects on GABAergic synaptic plasticity in hippocampus.
Journal: Journal of neurophysiology 20030401
Title: Adrenal function under long-term raloxifene administration.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20030401
Title: Allopregnanolone serum levels and expression of 5 alpha-reductase and 3 alpha-hydroxysteroid dehydrogenase isoforms in hippocampal and temporal cortex of patients with epilepsy.
Journal: Epilepsy research 20030401
Title: Inter-ictal and post-ictal circulating levels of allopregnanolone, an anticonvulsant metabolite of progesterone, in epileptic children.
Journal: Epilepsy research 20030401
Title: Effect of acute ethanol administration and acute allopregnanolone administration on spontaneous hippocampal pyramidal cell neural activity.
Journal: Brain research 20030328
Title: Seizure exacerbation associated with inhibition of progesterone metabolism.
Journal: Annals of neurology 20030301
Title: Neuroactive steroid levels in patients with panic disorder.
Journal: The American journal of psychiatry 20030301
Title: Perinatal neurosteroid levels influence GABAergic interneuron localization in adult rat prefrontal cortex.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030301
Title: Pharmacological characterization of the homomeric and heteromeric UNC-49 GABA receptors in C. elegans.
Journal: British journal of pharmacology 20030301
Title: Synthesis and GABA(A) receptor activity of a 6,19-oxido analogue of pregnanolone.
Journal: Bioorganic & medicinal chemistry letters 20030210
Title: Oxytocin regulates neurosteroid modulation of GABA(A) receptors in supraoptic nucleus around parturition.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030201
Title: Induced panic attacks shift gamma-aminobutyric acid type A receptor modulatory neuroactive steroid composition in patients with panic disorder: preliminary results.
Journal: Archives of general psychiatry 20030201
Title: Selective and potent inhibitors of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) that metabolizes neurosteroids derived from progesterone.
Journal: Chemico-biological interactions 20030201
Title: GABA receptors, progesterone and premenstrual dysphoric disorder.
Journal: Archives of women's mental health 20030201
Title: Effect of different hormonal replacement therapies on circulating allopregnanolone and dehydroepiandrosterone levels in postmenopausal women.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20030201
Title: Neurosteroids in depression: a review.
Journal: Psychopharmacology 20030101
Title: Olanzapine and clozapine increase the GABAergic neuroactive steroid allopregnanolone in rodents.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030101
Title: On the putative physiological role of allopregnanolone on GABA(A) receptor function.
Journal: Neuropharmacology 20030101
Title: Pregnanolone isomers, pregnenolone and their polar conjugates around parturition.
Journal: Physiological research 20030101
Title: Increased neurosteroid sensitivity of hippocampal GABAA receptors during postnatal development.
Journal: Neuroscience 20030101
Title: Serum allopregnanolone levels relate to FSFI score during the menstrual cycle.
Journal: Journal of sex & marital therapy 20030101
Title: Effects of neurosteroids on epileptiform activity induced by picrotoxin and 4-aminopyridine in the rat hippocampal slice.
Journal: Epilepsy research 20030101
Title: A synthesis of 3alpha,6alpha,17alpha-trihydroxy-5beta-pregnan-20-one (triolone) from 3alpha,6alpha-dihydroxy-5beta-pregnan-20-one (diolone).
Journal: Acta poloniae pharmaceutica 20030101
Title: Inhibitory effect of some neuroactive steroids on cocaine-induced kindling in mice.
Journal: Polish journal of pharmacology 20030101
Title: The third multidisciplinary conference on drug research, Piła 2002. Effects of 1alpha,25-dihydroxyvitamin D3 and some putative steroid neuroprotective agents on the hydrogen peroxide-induced damage in neuroblastoma-glioma hybrid NG108-15 cells.
Journal: Acta poloniae pharmaceutica 20030101
Title: Allopregnanolone modulates spontaneous GABA release via presynaptic Cl- permeability in rat preoptic nerve terminals.
Journal: Brain research 20021227
Title: Allopregnanolone enhancement of GABAergic transmission in rat medial preoptic area neurons.
Journal: American journal of physiology. Endocrinology and metabolism 20021201
Title: Progesterone enhances ethanol-induced modulation of mesocortical dopamine neurons: antagonism by finasteride.
Journal: Journal of neurochemistry 20021201
Title: Changes in GABA(A) receptor gene expression induced by withdrawal of, but not by long-term exposure to, ganaxolone in cultured rat cerebellar granule cells.
Journal: The Journal of pharmacology and experimental therapeutics 20021201
Title: Endotoxin increases sleep and brain allopregnanolone concentrations in newborn lambs.
Journal: Pediatric research 20021201
Title: A caspase-3-dependent pathway is predominantly activated by the excitotoxin pregnenolone sulfate and requires early and late cytochrome c release and cell-specific caspase-2 activation in the retinal cell death.
Journal: Journal of neurochemistry 20021201
Title: Behavioral action of ethanol in Porsolt's forced swim test: modulation by 3 alpha-hydroxy-5 alpha-pregnan-20-one.
Journal: Neuropharmacology 20021201
Title: Conjugated equine estrogens, estrone sulphate and estradiol valerate oral administration in ovariectomized rats: effects on central and peripheral allopregnanolone and beta-endorphin.
Journal: Maturitas 20021120
Title: Kinetics of allopregnanolone formation catalyzed by human 3 alpha-hydroxysteroid dehydrogenase type III (AKR1C2).
Journal: Biochemistry 20021112
Title: Acute hypoxic hypoxia alters GABA(A) receptor modulation by allopregnanolone and pentobarbital in embryonic chick optic lobe.
Journal: Brain research 20021108
Title: Neuroactive steroids differ in potency but not in intrinsic efficacy at the GABA(A) receptor in vivo.
Journal: The Journal of pharmacology and experimental therapeutics 20021101
Title: Acute and chronic effects of the neuroactive steroid pregnanolone on schedule-controlled responding in rhesus monkeys.
Journal: Behavioural pharmacology 20021101
Title: Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients.
Journal: The Journal of clinical endocrinology and metabolism 20021101
Title: Acute ethanol administration and acute allopregnanolone administration impair spatial memory in the Morris water task.
Journal: Alcoholism, clinical and experimental research 20021101
Title: Allopregnanolone levels and symptom improvement in severe premenstrual syndrome.
Journal: Journal of clinical psychopharmacology 20021001
Title: Functional characterization of GABA(A) receptors in neonatal hypothalamic brain slice.
Journal: Journal of neurophysiology 20021001
Title: Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cepsilon.
Journal: The Journal of clinical investigation 20021001
Title: Social and neural determinants of aggressive behavior: pharmacotherapeutic targets at serotonin, dopamine and gamma-aminobutyric acid systems.
Journal: Psychopharmacology 20021001
Title: Aggressive behavior as a reinforcer in mice: activation by allopregnanolone.
Journal: Psychopharmacology 20021001
Title: Levels of testosterone, allopregnanolone and homocysteine in severe hypothyroidism.
Journal: Clinical chemistry and laboratory medicine 20021001
Title: Allopregnanolone activates GABA(A) receptor/Cl(-) channels in a multiphasic manner in embryonic rat hippocampal neurons.
Journal: Journal of neurophysiology 20020901
Title: Cortical gamma-aminobutyric acid levels across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder: a proton magnetic resonance spectroscopy study.
Journal: Archives of general psychiatry 20020901
Title: Biosynthesis of steroids in ovarian follicles of red seabream, Pagrus major (Sparidae, Teleostei) during final oocyte maturation and the relative effectiveness of steroid metabolites for germinal vesicle breakdown in vitro.
Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020901
Title: Changes in expression of the neuropeptide Y Y1 receptor gene in the medial amygdala of transgenic mice during pregnancy and after delivery.
Journal: Journal of neurochemistry 20020901
Title: Allopregnanolone attenuates N-methyl-D-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture.
Journal: Neuroscience letters 20020802
Title: Neonatal isolation alters stress hormone and mesolimbic dopamine release in juvenile rats.
Journal: Pharmacology, biochemistry, and behavior 20020801
Title: Alcohol-induced c-Fos expression in the Edinger-Westphal nucleus: pharmacological and signal transduction mechanisms.
Journal: The Journal of pharmacology and experimental therapeutics 20020801
Title: Differential effects of allopregnanolone and GABA on kainate-induced lactate dehydrogenase release in cultured rat cerebral cortical cells.
Journal: Acta pharmacologica Sinica 20020801
Title: Alteration of voluntary ethanol and saccharin consumption by the neurosteroid allopregnanolone in mice.
Journal: Psychopharmacology 20020801
Title: Allopregnanolone increase in striatal N-methyl-D-aspartic acid evoked [3H]dopamine release is estrogen and progesterone dependent.
Journal: Cellular and molecular neurobiology 20020801
Title: Reinforcing effects of the neurosteroid allopregnanolone in rats.
Journal: Pharmacology, biochemistry, and behavior 20020701
Title: Antagonism of picrotoxin-induced changes in dopamine and serotonin metabolism by allopregnanolone and midazolam.
Journal: Pharmacology, biochemistry, and behavior 20020701
Title: Initial sensitivity, tolerance and cross-tolerance to allopregnanolone- and ethanol-induced hypothermia in selected mouse lines.
Journal: Psychopharmacology 20020701
Title: The neurosteroid allopregnanolone increases dopamine release and dopaminergic response to morphine in the rat nucleus accumbens.
Journal: The European journal of neuroscience 20020701
Title: Low pregnenolone sulphate plasma concentrations in patients with generalized social phobia.
Journal: Psychological medicine 20020701
Title: The clinical potentials of endogenous neurosteroids.
Journal: Drugs of today (Barcelona, Spain : 1998) 20020701
Title: Discriminative stimulus effects of ethanol in C57BL/6J and DBA/2J inbred mice.
Journal: Alcoholism, clinical and experimental research 20020601
Title: Prevention of the stress-induced increase in the concentration of neuroactive steroids in rat brain by long-term administration of mirtazapine but not of fluoxetine.
Journal: Journal of psychopharmacology (Oxford, England) 20020601
Title: Effect of allopregnanolone on d-[3H]-aspartate release and [3H]-glutamate uptake in the hippocampus of kainate-treated mice.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20020601
Title: Rapid anxiolytic activity of progesterone and pregnanolone in male rats.
Journal: Pharmacology, biochemistry, and behavior 20020601
Title: Female Wistar rats tested during late proestrus or during pregnancy and ovariectomized rats tested after receiving progesterone or allopregnanolone displayed reduced conflict behavior.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20020601
Title: Gonadal steroids, brain, and behavior: role of context.
Journal: Dialogues in clinical neuroscience 20020601
Title: Allopregnanolone inhibits learning in the Morris water maze.
Journal: Brain research 20020503
Title: Neuroactive steroid changes in response to challenge with the panicogenic agent pentagastrin.
Journal: Psychoneuroendocrinology 20020501
Title: Withdrawal properties of a neuroactive steroid: implications for GABA(A) receptor gene regulation in the brain and anxiety behavior.
Journal: Steroids 20020501
Title: Changes in progesterone metabolites in the hippocampus can modulate open field and forced swim test behavior of proestrous rats.
Journal: Hormones and behavior 20020501
Title: The neurosteroid 3 alpha-hydroxy-5 alpha-pregnan-20-one affects dopamine-mediated behavior in rodents.
Journal: Psychopharmacology 20020501
Title: High serum allopregnanolone levels in girls with precocious puberty.
Journal: The Journal of clinical endocrinology and metabolism 20020501
Title: Effects of the new generation selective estrogen receptor modulator EM-652 and oral administration of estradiol valerate on circulating, brain, and adrenal beta-endorphin and allopregnanolone levels in intact fertile and ovariectomized rats.
Journal: Fertility and sterility 20020501
Title: GABA(B) receptor-mediated increase of neurosteroids by gamma-hydroxybutyric acid.
Journal: Neuropharmacology 20020501
Title: Depletion of cortical allopregnanolone potentiates stress-induced increase in cortical dopamine output.
Journal: Brain research 20020405
Title: Homocysteine and steroids levels in metformin treated women with polycystic ovary syndrome.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20020401
Title: Two neuroactive steroids in midpregnancy as measured in maternal and fetal sera and in amniotic fluid.
Journal: Steroids 20020401
Title: Modulation Of [35S]-tert-butylbicyclophosphorothionate binding by somatostatin in rat hypothalamus.
Journal: Clinical and experimental pharmacology & physiology 20020401
Title: Substrate specificity of human 3(20)alpha-hydroxysteroid dehydrogenase for neurosteroids and its inhibition by benzodiazepines.
Journal: Biological & pharmaceutical bulletin 20020401
Title: A rapid method for obtaining finasteride, a 5alpha-reductase inhibitor, from commercial tablets.
Journal: Brain research. Brain research protocols 20020401
Title: GABAergic neurosteroid modulation of ethanol actions.
Journal: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20020401
Title: The effects of the neuroactive steroid 3 alpha,5 alpha-THDOC on sleep in the rat.
Journal: Neuroreport 20020325
Title: Daily treatment with diazepam differentially modifies sensitivity to the effects of gamma-aminobutyric acid(A) modulators on schedule-controlled responding in rhesus monkeys.
Journal: The Journal of pharmacology and experimental therapeutics 20020301
Title: Pulsatile secretory characteristics of allopregnanolone, a neuroactive steroid, during the menstrual cycle and in amenorrheic subjects.
Journal: European journal of endocrinology 20020301
Title: Changes in GABAA receptor gamma 2 subunit gene expression induced by long-term administration of oral contraceptives in rats.
Journal: Neuropharmacology 20020301
Title: Effect of centrally injected allopregnanolone on sexual receptivity, luteinizing hormone release, hypothalamic dopamine turnover, and release in female rats.
Journal: Endocrine 20020301
Title: Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids.
Journal: British journal of pharmacology 20020201
Title: Increased response of plasma allopregnanolone to corticotropin-releasing hormone in obese patients.
Journal: Neuroendocrinology 20020201
Title: Can molecular similarity-activity models for intravenous general anaesthetics help explain their mechanism of action?
Journal: British journal of anaesthesia 20020201
Title: Sensitivity to the locomotor stimulant effects of ethanol and allopregnanolone is influenced by common genes.
Journal: Behavioral neuroscience 20020201
Title: Social isolation stress during the third week of life has age-dependent effects on spatial learning in rats.
Journal: Behavioural brain research 20020122
Title: GABA(A) receptor-modulating neuroactive steroid composition in patients with panic disorder before and during paroxetine treatment.
Journal: The American journal of psychiatry 20020101
Title: Prenatal diazepam exposure functionally alters the GABA(A) receptor that modulates [3H]noradrenaline release from rat hippocampal synaptosomes.
Journal: Developmental neuroscience 20020101
Title: Ventral tegmental area infusions of inhibitors of the biosynthesis and metabolism of 3alpha,5alpha-THP attenuate lordosis of hormone-primed and behavioural oestrous rats and hamsters.
Journal: Journal of neuroendocrinology 20011201
Title: The interaction between ethanol and pregnanolone at induction of anaesthesia investigated with a threshold method in male rats.
Journal: British journal of pharmacology 20011201
Title: Diminished allopregnanolone enhancement of GABA(A) receptor currents in a rat model of chronic temporal lobe epilepsy.
Journal: The Journal of physiology 20011201
Title: Steroid structure and pharmacological properties determine the anti-amnesic effects of pregnenolone sulphate in the passive avoidance task in rats.
Journal: The European journal of neuroscience 20011201
Title: 3Alpha-hydroxy-5alpha-pregnan-20-one levels and GABA(A) receptor-mediated 36Cl(-) flux across development in rat cerebral cortex.
Journal: Brain research. Developmental brain research 20011126
Title: Neuroactive steroids modulate crustacean locomotor activity.
Journal: Neuroscience letters 20011102
Title: Influence of membrane cholesterol on modulation of the GABA(A) receptor by neuroactive steroids and other potentiators.
Journal: British journal of pharmacology 20011101
Title: The negative GABA(A) modulator methyl beta-carboline-3-carboxylate attenuates the behavioral effects of the positive GABA(A) modulators triazolam and pregnanolone in rhesus monkeys.
Journal: Psychopharmacology 20011101
Title: Role of allopregnanolone in regulation of GABA(A) receptor plasticity during long-term exposure to and withdrawal from progesterone.
Journal: Brain research. Brain research reviews 20011101
Title: The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5alpha-dihydroprogesterone in psychiatric disorders.
Journal: Brain research. Brain research reviews 20011101
Title: alpha4beta3delta GABA(A) receptors characterized by fluorescence resonance energy transfer-derived measurements of membrane potential.
Journal: The Journal of biological chemistry 20011019
Title: The influence of subchronic administration of the neurosteroid allopregnanolone on sleep in the rat.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20011001
Title: Pressure-sensitive and -insensitive coupling in gamma-aminobutyric acid(A) receptors.
Journal: Psychopharmacology 20011001
Title: Increased expression of the neuropeptide Y receptor Y(1) gene in the medial amygdala of transgenic mice induced by long-term treatment with progesterone or allopregnanolone.
Journal: Journal of neurochemistry 20011001
Title: Allopregnanolone and pentobarbital infused into the nucleus accumbens substitute for the discriminative stimulus effects of ethanol.
Journal: Alcoholism, clinical and experimental research 20011001
Title: Neuroendocrine effects of raloxifene hydrochloride in postmenopausal women.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20011001
Title: Early postnatal ethanol intubation blunts GABA(A) receptor up-regulation and modifies 3alpha-hydroxy-5alpha-pregnan-20-one sensitivity in rat MS/DB neurons.
Journal: Brain research. Developmental brain research 20010923
Title: Immunohistochemical localization of 3 beta-hydroxysteroid dehydrogenase and 5 alpha-reductase in the brain of the African lungfish Protopterus annectens.
Journal: The Journal of comparative neurology 20010917
Title: Potency of positive gamma-aminobutyric acid(A) modulators to substitute for a midazolam discriminative stimulus in untreated monkeys does not predict potency to attenuate a flumazenil discriminative stimulus in diazepam-treated monkeys.
Journal: The Journal of pharmacology and experimental therapeutics 20010901
Title: Inhibiting progesterone metabolism in the hippocampus of rats in behavioral estrus decreases anxiolytic behaviors and enhances exploratory and antinociceptive behaviors.
Journal: Cognitive, affective & behavioral neuroscience 20010901
Title: 3alpha,5alpha-THP in the raphe magnus attenuates PTZ-induced myoclonic seizures.
Journal: Brain research 20010824
Title: Effects of progesterone synthesized de novo in the developing Purkinje cell on its dendritic growth and synaptogenesis.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010815
Title: Tolerance to the anticonvulsant activity of midazolam and allopregnanolone in a model of picrotoxin seizures.
Journal: European journal of pharmacology 20010810
Title: Effect of treatment of hypothyroidism on the plasma concentrations of neuroactive steroids and homocysteine.
Journal: Clinical chemistry and laboratory medicine 20010801
Title: Sensitivity of synaptic GABA(A) receptors to allosteric modulators in hippocampal oriens-alveus interneurons.
Journal: Synapse (New York, N.Y.) 20010701
Title: Neuroactive steroids, their precursors and polar conjugates during parturition and postpartum in maternal blood: 2. Time profiles of pregnanolone isomers.
Journal: The Journal of steroid biochemistry and molecular biology 20010701
Title: Effect of 5 alpha-pregnan-3 alpha-ol-20-one on nitric oxide biosynthesis and plasma volume in rats.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010601
Title: Allosteric modulation in spontaneously active mutant gamma-aminobutyric acidA receptors.
Journal: Neuroscience letters 20010601
Title: Increased behavioral neurosteroid sensitivity in a rat line selectively bred for high alcohol sensitivity.
Journal: European journal of pharmacology 20010601
Title: Sensitivity to a neurosteroid is increased during addition of progestagen to postmenopausal hormone replacement therapy.
Journal: Neuroendocrinology 20010601
Title: In ovo chronic neurosteroid treatment affects the function and allosteric interactions of GABA(A) receptor modulatory sites.
Journal: Brain research 20010525
Title: Characterization of discriminative stimulus effects of the neuroactive steroid pregnanolone.
Journal: The Journal of pharmacology and experimental therapeutics 20010501
Title: Effect of alpha subunit on allosteric modulation of ion channel function in stably expressed human recombinant gamma-aminobutyric acid(A) receptors determined using (36)Cl ion flux.
Journal: Molecular pharmacology 20010501
Title: Regulation of uterine gamma-aminobutyric acid(A) receptor subunit expression throughout pregnancy.
Journal: Endocrinology 20010501
Title: Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder.
Journal: Biological psychiatry 20010501
Title: Behavioral characterization of Co 134444 (3alpha-hydroxy-21-(1'-imidazolyl)-3beta-methoxymethyl-5alpha- pregnan-20-one), a novel sedative-hypnotic neuroactive steroid.
Journal: Psychopharmacology 20010501
Title: Effects of CRH and ACTH administration on plasma and brain neurosteroid levels.
Journal: Neurochemical research 20010501
Title: Cataleptic effect of neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one in mice: modulation by serotonergic agents.
Journal: Brain research 20010413
Title: Functional modulation of gamma-aminobutyric acid(A) receptors by etifoxine and allopregnanolone in rodents.
Journal: Neuroscience letters 20010406
Title: The anxiolytic effect of allopregnanolone is associated with gonadal hormonal status in female rats.
Journal: European journal of pharmacology 20010406
Title: Diethylstilbestrol regulates trophoblast stem cell differentiation as a ligand of orphan nuclear receptor ERR beta.
Journal: Genes & development 20010401
Title: Antiprogestagen activity of 5H-progesterone metabolites and their analogues, 16alpha,17alpha-cyclohexane-5H-pregnan-3,20-diones.
Journal: Bulletin of experimental biology and medicine 20010401
Title: Synergistic protection of allopregnanolone and phenobarbital against maximal electroshock seizures in mice.
Journal: Acta pharmacologica Sinica 20010401
Title: Allopregnanolone assays.
Journal: The Journal of clinical endocrinology and metabolism 20010301
Title: Neurosteroid withdrawal model of perimenstrual catamenial epilepsy.
Journal: Epilepsia 20010301
Title: Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy.
Journal: Epilepsia 20010301
Title: Evaluation and comparison of the pharmacokinetic and pharmacodynamic properties of allopregnanolone and pregnanolone at induction of anaesthesia in the male rat.
Journal: British journal of anaesthesia 20010301
Title: Self-augmentation effect of male-specific products on sexually differentiated progesterone metabolism in adult male rat liver microsomes.
Journal: The Journal of biological chemistry 20010216
Title: A high-performance liquid chromatography-tandem mass spectrometric method for the determination of pharmacokinetics of ganaxolone in rat, monkey, dog and human plasma.
Journal: Journal of chromatography. B, Biomedical sciences and applications 20010210
Title: Suppressing aggressive behavior with analogs of allopregnanolone (epalon).
Journal: Steroids 20010201
Title: Circulating levels of allopregnanolone, an anticonvulsant metabolite of progesterone, in women with partial epilepsy in the postcritical phase.
Journal: Epilepsia 20010201
Title: Alcohol, allopregnanolone and aggression in mice.
Journal: Psychopharmacology 20010201
Title: Characterization of gamma-aminobutyrate type A receptors with atypical coupling between agonist and convulsant binding sites in discrete brain regions.
Journal: Brain research. Molecular brain research 20010131
Title: Allopregnanolone, pregnenolone sulfate, and epitestosterone in breast cyst fluid.
Journal: Steroids 20010101
Title: Serum allopregnanolone in women with postpartum 'blues'.
Journal: Obstetrics and gynecology 20010101
Title: Dehydroepiandrosterone sulphate prevents oxygen-glucose deprivation-induced injury in cerebellar granule cell culture.
Journal: Neuroscience 20010101
Title: Plasma levels of neuroactive steroids are increased in untreated women with anorexia nervosa or bulimia nervosa.
Journal: Psychosomatic medicine 20010101
Title: Application of an enzyme-immunoassay (EIA) for rapid screening of 5 alpha-pregnane-3,20-dione (DHP) in blood plasma of the Asian elephant, Elephas maximus.
Journal: Berliner und Munchener tierarztliche Wochenschrift 20010101
Title: Neuroactive steroid levels in patients with generalized anxiety disorder.
Journal: The Journal of neuropsychiatry and clinical neurosciences 20010101
Title: Responses to laboratory psychosocial stress in postpartum women.
Journal: Psychosomatic medicine 20010101
Title: Physiological roles for the neurosteroid allopregnanolone in the modulation of brain function during pregnancy and parturition.
Journal: Progress in brain research 20010101
Title: Stress and neuroactive steroids.
Journal: International review of neurobiology 20010101
Title: Neurosteroids in learning and memory processes.
Journal: International review of neurobiology 20010101
Title: Neurosteroids and behavior.
Journal: International review of neurobiology 20010101
Title: Biosynthesis of neurosteroids and regulation of their synthesis.
Journal: International review of neurobiology 20010101
Title: Ethanol and neurosteroid interactions in the brain.
Journal: International review of neurobiology 20010101
Title: Clinical implications of circulating neurosteroids.
Journal: International review of neurobiology 20010101
Title: Current perspectives on the role of neurosteroids in PMS and depression.
Journal: International review of neurobiology 20010101
Title: Two conserved arginines in the extracellular N-terminal domain of the GABA(A) receptor alpha(5) subunit are crucial for receptor function.
Journal: Journal of neurochemistry 20001001
Title: Heterogeneity of GABA(A) receptor-mediated responses in the human IMR-32 neuroblastoma cell line.
Journal: Journal of neuroscience research 20000515
Title: Anti-seizure effects of progesterone and 3alpha,5alpha-THP in kainic acid and perforant pathway models of epilepsy.
Journal: Psychoneuroendocrinology 20000501
Title: Neocortical hyperexcitability after GABA withdrawal in vitro.
Journal: Epilepsy research 20000301
Title: Cyclic withdrawal from endogenous and exogenous progesterone increases kainic acid and perforant pathway induced seizures.
Journal: Pharmacology, biochemistry, and behavior 19990201
Title: Progesterone withdrawal I: pro-convulsant effects.
Journal: Brain research 19981005
Title: Withdrawal from 3alpha-OH-5alpha-pregnan-20-One using a pseudopregnancy model alters the kinetics of hippocampal GABAA-gated current and increases the GABAA receptor alpha4 subunit in association with increased anxiety.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19980715
Title: Influence of premedication with diazepam or morphine on the induction dose of eltanolone.
Journal: Acta anaesthesiologica Scandinavica 19980501
Title: Pentobarbital decreases the gamma-aminobutyric acidA receptor subunit gamma-2 long/short mRNA ratio by a mechanism distinct from receptor occupation.
Journal: The Journal of pharmacology and experimental therapeutics 19971001
Title: Cerebellar gamma-aminobutyric acid type A receptors: pharmacological subtypes revealed by mutant mouse lines.
Journal: Molecular pharmacology 19970901
Title: Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Journal: Nature 19970227
Title: Ventilatory effects of eltanolone during induction of anaesthesia: comparison with propofol and thiopentone.
Journal: British journal of anaesthesia 19960801
Title: Cloning of cDNAs encoding the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors.
Journal: Molecular pharmacology 19960201
Title: The neurosteroid tetrahydroprogesterone counteracts corticotropin-releasing hormone-induced anxiety and alters the release and gene expression of corticotropin-releasing hormone in the rat hypothalamus.
Journal: Neuroscience 19940901
Title: Mitochondrial diazepam-binding inhibitor receptor complex agonists antagonize dizocilpine amnesia: putative role for allopregnanolone.
Journal: The Journal of pharmacology and experimental therapeutics 19940701
Title: A novel allosteric modulatory site on the GABAA receptor beta subunit.
Journal: Neuron 19940401
Title: 5 alpha-Pregnan-3 alpha-ol-20-one blocks nicotine-induced seizures and enhances paired-pulse inhibition.
Journal: European journal of pharmacology 19900828
