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Home Other Building Blocks 257892-31-2
257892-31-2,MFCD08063704
Catalog No.:AA00C33F

257892-31-2 | N-DESMETHYL ROSIGLITAZONE

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$149.00   $104.00
- +
5mg
≥98%
in stock  
$565.00   $395.00
- +
10mg
≥98%
in stock  
$938.00   $656.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C33F
Chemical Name:
N-DESMETHYL ROSIGLITAZONE
CAS Number:
257892-31-2
Molecular Formula:
C17H17N3O3S
Molecular Weight:
343.4002
MDL Number:
MFCD08063704
SMILES:
O=C1NC(=O)C(S1)Cc1ccc(cc1)OCCNc1ccccn1
Properties
Computed Properties
 
Complexity:
441  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
1  
XLogP3:
3  

Literature

Title: The effects of febuxostat on the pharmacokinetic parameters of rosiglitazone, a CYP2C8 substrate.

Journal: British journal of clinical pharmacology 20120801

Title: Influence of cholestyramine on the pharmacokinetics of rosiglitazone and its metabolite, desmethylrosiglitazone, after oral and intravenous dosing of rosiglitazone: impact on oral bioavailability, absorption, and metabolic disposition in rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20060901

Title: Effect of quercetin on the pharmacokinetics of rosiglitazone, a CYP2C8 substrate, in healthy subjects.

Journal: Journal of clinical pharmacology 20050801

Title: Gemfibrozil considerably increases the plasma concentrations of rosiglitazone.

Journal: Diabetologia 20031001

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SDS
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