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28399-31-7,MFCD09265251
Catalog No.:AA00C4FZ

28399-31-7 | 8-(2-((2-Pentylcyclopropyl)methyl)cyclopropyl)octanoic acid

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1mg
≥95%
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$218.00   $152.00
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5mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C4FZ
Chemical Name:
8-(2-((2-Pentylcyclopropyl)methyl)cyclopropyl)octanoic acid
CAS Number:
28399-31-7
Molecular Formula:
C20H36O2
Molecular Weight:
308.4986
MDL Number:
MFCD09265251
SMILES:
CCCCCC1CC1CC1CC1CCCCCCCC(=O)O
Properties
Computed Properties
 
Complexity:
326  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
14  
Undefined Atom Stereocenter Count:
4  
XLogP3:
7.7  

Literature

Title: 8-[2-(2-Pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid and its diastereomers improve age-related cognitive deterioration.

Journal: Lipids 20120701

Title: Linoleic acid derivative DCP-LA stimulates vesicular transport of α7 ACh receptors towards surface membrane.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

Title: PKC ε activation prevents synaptic loss, Aβ elevation, and cognitive deficits in Alzheimer's disease transgenic mice.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110112

Title: α, β-DCP-LA selectively activates PKC-ε and stimulates neurotransmitter release with the highest potency among 4 diastereomers.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101

Title: Linoleic acid derivative DCP-LA protects neurons from oxidative stress-induced apoptosis by inhibiting caspase-3/-9 activation.

Journal: Neurochemical research 20100501

Title: DCP-LA neutralizes mutant amyloid beta peptide-induced impairment of long-term potentiation and spatial learning.

Journal: Behavioural brain research 20100105

Title: DCP-LA stimulates AMPA receptor exocytosis through CaMKII activation due to PP-1 inhibition.

Journal: Journal of cellular physiology 20091001

Title: The linoleic acid derivative DCP-LA selectively activates PKC-epsilon, possibly binding to the phosphatidylserine binding site.

Journal: Journal of lipid research 20060601

Title: Linoleic acid derivative DCP-LA improves learning impairment in SAMP8.

Journal: Neuroreport 20060123

Title: 8-[2-(2-pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid stimulates GABA release from interneurons projecting to CA1 pyramidal neurons in the rat hippocampus via pre-synaptic alpha7 acetylcholine receptors.

Journal: Journal of neurochemistry 20051101

Title: The newly synthesized linoleic acid derivative FR236924 induces a long-lasting facilitation of hippocampal neurotransmission by targeting nicotinic acetylcholine receptors.

Journal: Bioorganic & medicinal chemistry letters 20030324

Title: Kanno T, et al. DCP-LA Activates Cytosolic PKCε by Interacting with the Phosphatidylserine Binding/Associating Sites Arg50 and Ile89 in the C2-Like Domain. Cell Physiol Biochem. 2015;37(1):193-200.

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Tags:28399-31-7 Molecular Formula|28399-31-7 MDL|28399-31-7 SMILES|28399-31-7 8-(2-((2-Pentylcyclopropyl)methyl)cyclopropyl)octanoic acid