Home Amines 200189-97-5
200189-97-5,MFCD09970490
Catalog No.:AA00C4F8

200189-97-5 | N-(Dibenz[b,f]oxepin-10-ylmethyl)-N-Methyl-N-(2-propynyl)aminemaleate

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1mg
≥98%
in stock  
$43.00   $30.00
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5mg
≥98%
in stock  
$149.00   $104.00
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25mg
≥99%(HPLC)
in stock  
$543.00   $380.00
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50mg
≥99%(HPLC)
in stock  
$834.00   $584.00
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100mg
≥99%(HPLC)
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$1,320.00   $924.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C4F8
Chemical Name:
N-(Dibenz[b,f]oxepin-10-ylmethyl)-N-Methyl-N-(2-propynyl)aminemaleate
CAS Number:
200189-97-5
Molecular Formula:
C23H21NO5
Molecular Weight:
391.4165
MDL Number:
MFCD09970490
SMILES:
OC(=O)/C=C\C(=O)O.C#CCN(CC1=Cc2ccccc2Oc2c1cccc2)C
Properties
Computed Properties
 
Complexity:
551  
Covalently-Bonded Unit Count:
2  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  

Literature

Title: Apoptosis inhibitors and mini-agrin have additive benefits in congenital muscular dystrophy mice.

Journal: EMBO molecular medicine 20110801

Title: Omigapil ameliorates the pathology of muscle dystrophy caused by laminin-alpha2 deficiency.

Journal: The Journal of pharmacology and experimental therapeutics 20091201

Title: Targets for neuroprotection in Parkinson's disease.

Journal: Biochimica et biophysica acta 20090701

Title: Phase II/III randomized trial of TCH346 in patients with ALS.

Journal: Neurology 20070821

Title: Post-translational protein modifications in type 1 diabetes: a role for the repair enzyme protein-L-isoaspartate (D-aspartate) O-methyltransferase?

Journal: Diabetologia 20070301

Title: TCH346 as a neuroprotective drug in Parkinson's disease: a double-blind, randomised, controlled trial.

Journal: The Lancet. Neurology 20061201

Title: High-resolution structure of human D-glyceraldehyde-3-phosphate dehydrogenase.

Journal: Acta crystallographica. Section D, Biological crystallography 20060301

Title: The use of LC/MS, GC/MS, and LC/NMR hyphenated techniques to identify a drug degradation product in pharmaceutical development.

Journal: Journal of pharmaceutical and biomedical analysis 20060224

Title: CGP 3466B has no effect on disease course of (G93A) mSOD1 transgenic mice.

Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20041201

Title: Preclinical evidence for neuroprotection with monoamine oxidase-B inhibitors in Parkinson's disease.

Journal: Neurology 20041012

Title: Clinical trials of neuroprotection for Parkinson's disease.

Journal: Neurology 20041012

Title: Amyotrophic lateral sclerosis: a consensus viewpoint on designing and implementing a clinical trial.

Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20040601

Title: Simultaneous analytical method for the determination of TCH346 and its four metabolites in human plasma by liquid chromatography/tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20040101

Title: CGP 3466 increases survival of cultured fetal dopaminergic neurons.

Journal: Restorative neurology and neuroscience 20030101

Title: Sarina Meinen, et al. Apoptosis inhibitors and mini-agrin have additive benefits in congenital muscular dystrophy mice. EMBO Mol Med. 2011 Aug;3(8):465-79.

Title: Tanusree Sen, et al. Nitrosylation of GAPDH augments pathological tau acetylation upon exposure to amyloid-β. Sci Signal. 2018 Mar 20;11(522):eaao6765.

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SDS
Tags:200189-97-5 Molecular Formula|200189-97-5 MDL|200189-97-5 SMILES|200189-97-5 N-(Dibenz[b,f]oxepin-10-ylmethyl)-N-Methyl-N-(2-propynyl)aminemaleate