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28259-97-4,MFCD00078086
Catalog No.:AA01X3YF

28259-97-4 | 2-Butenedioic acid, 2-methyl-, (2Z)-, homopolymer

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01X3YF
Chemical Name:
2-Butenedioic acid, 2-methyl-, (2Z)-, homopolymer
CAS Number:
28259-97-4
Molecular Formula:
C5H6O4
Molecular Weight:
130.0987
MDL Number:
MFCD00078086
SMILES:
OC(=O)/C=C(\C(=O)O)/C
Properties
Computed Properties
 
Complexity:
168  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
-0.1  

Literature

Title: Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics.

Journal: Scientific reports 20180101

Title: Fumarate Mediates a Chronic Proliferative Signal in Fumarate Hydratase-Inactivated Cancer Cells by Increasing Transcription and Translation of Ferritin Genes.

Journal: Molecular and cellular biology 20170601

Title: Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20160608

Title: Regulation of proton-coupled folate transporter in retinal Müller cells by the antipsoriatic drug monomethylfumarate.

Journal: Glia 20120301

Title: Downregulation of endothelial adhesion molecules by dimethylfumarate, but not monomethylfumarate, and impairment of dynamic lymphocyte-endothelial cell interactions.

Journal: Experimental dermatology 20111201

Title: Vitamin B12, cognition, and brain MRI measures: a cross-sectional examination.

Journal: Neurology 20110927

Title: Lymphomatosis cerebri presenting as a rapidly progressive dementia with a high methylmalonic acid.

Journal: Journal of neurology 20110801

Title: Clinical characteristics and gene mutation analysis of methylmalonic aciduria.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20110601

Title: A methylaspartate cycle in haloarchaea.

Journal: Science (New York, N.Y.) 20110121

Title: Cytokine secretion pattern in treatment of lymphocytes of multiple sclerosis patients with fumaric acid esters.

Journal: Immunological investigations 20110101

Title: Pharmacokinetics of anti-psoriatic fumaric acid esters in psoriasis patients.

Journal: Archives of dermatological research 20100901

Title: Synthesis, characterization and reactivity ratio study of poly(di(tri-n-butyltin) citraconate-co-N-vinylimidazole).

Journal: Molecules (Basel, Switzerland) 20100707

Title: Reduction of fumarate, mesaconate and crotonate by Mfr, a novel oxygen-regulated periplasmic reductase in Campylobacter jejuni.

Journal: Environmental microbiology 20100301

Title: Effects of fumaric acids on cuprizone induced central nervous system de- and remyelination in the mouse.

Journal: PloS one 20100101

Title: Catalytic (transfer) deuterogenation in D2O as deuterium source with H2 and HCO2H as electron sources.

Journal: Dalton transactions (Cambridge, England : 2003) 20090828

Title: Urinary methylmalonic acid in patients with acute myocardial infarction.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20090101

Title: The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist.

Journal: Biochemical and biophysical research communications 20081031

Title: A new antigen retrieval technique for human brain tissue.

Journal: PloS one 20080101

Title: Hyperkalemia after acute metabolic decompensation in two children with vitamin B12-unresponsive methylmalonic acidemia and normal renal function.

Journal: Clinical nephrology 20060701

Title: Fumarate reductase: structural and mechanistic insights from the catalytic reduction of 2-methylfumarate.

Journal: FEBS letters 20060306

Title: Effects of monomethylfumarate on dendritic cell differentiation.

Journal: The British journal of dermatology 20060201

Title: Reversing the effects of formalin fixation with citraconic anhydride and heat: a universal antigen retrieval method.

Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20050101

Title: Monomethylfumarate affects polarization of monocyte-derived dendritic cells resulting in down-regulated Th1 lymphocyte responses.

Journal: European journal of immunology 20040201

Title: In vitro pharmacokinetics of anti-psoriatic fumaric acid esters.

Journal: BMC pharmacology 20040101

Title: Plausible molecular mechanism for activation by fumarate and electron transfer of the dopamine beta-mono-oxygenase reaction.

Journal: The Biochemical journal 20021001

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Tags:28259-97-4 Molecular Formula|28259-97-4 MDL|28259-97-4 SMILES|28259-97-4 2-Butenedioic acid, 2-methyl-, (2Z)-, homopolymer