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383392-66-3,MFCD00469145
Catalog No.:AA00C6H8

383392-66-3 | Uc-112

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Purity
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5mg
≥98%(HPLC)
in stock  
$304.00   $213.00
- +
10mg
≥98%(HPLC)
in stock  
$445.00   $312.00
- +
25mg
≥98%(HPLC)
in stock  
$931.00   $652.00
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50mg
≥98%(HPLC)
in stock  
$1,559.00   $1,092.00
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100mg
≥98%(HPLC)
in stock  
$2,443.00   $1,710.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C6H8
Chemical Name:
Uc-112
CAS Number:
383392-66-3
Molecular Formula:
C22H24N2O2
Molecular Weight:
348.4382
MDL Number:
MFCD00469145
SMILES:
Oc1c(CN2CCCC2)cc(c2c1nccc2)COCc1ccccc1
Properties
Computed Properties
 
Complexity:
420  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
XLogP3:
3.3  

Literature

Title: Discovery of novel second mitochondria-derived activator of caspase mimetics as selective inhibitor of apoptosis protein inhibitors.

Journal: The Journal of pharmacology and experimental therapeutics 20140501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Wang J, et al. Discovery of novel second mitochondria-derived activator of caspase mimetics as selective inhibitor of apoptosis protein inhibitors. J Pharmacol Exp Ther. 2014 May;349(2):319-29.

Title: Qinghui Wang, et al. Synthesis and biological evaluation of indole-based UC-112 analogs as potent and selective survivin inhibitors. Eur J Med Chem

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SDS
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Tags:383392-66-3 Molecular Formula|383392-66-3 MDL|383392-66-3 SMILES|383392-66-3 Uc-112