+1 858-523-8231
Login | Register
menu
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
39524-08-8,MFCD25371916
Catalog No.:AA00C7AH

39524-08-8 | Asperosaponin VI

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98% by HPLC
in stock  
$77.00   $54.00
- +
10mg
≥98%
in stock  
$98.00   $68.00
- +
50mg
≥98%
in stock  
$432.00   $302.00
- +
100mg
≥98%
in stock  
$765.00   $535.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00C7AH
Chemical Name:
Asperosaponin VI
CAS Number:
39524-08-8
Molecular Formula:
C47H76O18
Molecular Weight:
929.0955
MDL Number:
MFCD25371916
SMILES:
OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](OC(=O)[C@]34CC[C@@]5(C(=CC[C@H]6[C@@]5(C)CC[C@@H]5[C@]6(C)CC[C@@H]([C@@]5(C)CO)O[C@@H]5OC[C@@H]([C@@H]([C@H]5O)O)O)[C@@H]4CC(CC3)(C)C)C)[C@@H]([C@H]([C@@H]2O)O)O)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Computed Properties
 
Complexity:
1770  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
23  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
65  
Hydrogen Bond Acceptor Count:
18  
Hydrogen Bond Donor Count:
11  
Isotope Atom Count:
0  
Rotatable Bond Count:
10  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
0.8  

Upstream Synthesis Route

[1]ChemicalandPharmaceuticalBulletin,1985,vol.33,#8,p.3473-3478

[1]ChemicalandPharmaceuticalBulletin,1985,vol.33,#8,p.3473-3478

[1]Phytochemistry,1993,vol.34,#5,p.1389-1394

Downstream Synthesis Route

[1]ChemicalandPharmaceuticalBulletin,1985,vol.33,p.3473-3478

[1]LiebigsAnnalenderChemie,1992,p.453-460

[1]Phytochemistry,1993,vol.34,p.1389-1394

[2]LiebigsAnnalenderChemie,1986,vol.1986,p.638-646

[1]ChemicalandPharmaceuticalBulletin,1985,vol.33,p.3473-3478

[1]Phytochemistry,1993,vol.34,p.1389-1394

Literature

Title: Long-term oral Asperosaponin VI attenuates cardiac dysfunction, myocardial fibrosis in a rat model of chronic myocardial infarction.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501

Title: Akebia saponin D attenuates ibotenic acid-induced cognitive deficits and pro-apoptotic response in rats: involvement of MAPK signal pathway.

Journal: Pharmacology, biochemistry, and behavior 20120501

Title: Determination of asperosaponin VI in dog plasma by high-performance liquid chromatography-tandem mass spectrometry and its application to a pilot pharmacokinetic study.

Journal: Biomedical chromatography : BMC 20120101

Title: Simultaneous determination of asperosaponin VI and its active metabolite hederagenin in rat plasma by liquid chromatography-tandem mass spectrometry with positive/negative ion-switching electrospray ionization and its application in pharmacokinetic study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115

Title: [Studies on optimizing preparation technics of wumeitougu oral liquid by response surface methodology].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110201

Title: Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways.

Journal: European journal of pharmacology 20101215

Title: In vitro & in vivo assessment of a herbal formula used topically for bone fracture treatment.

Journal: Journal of ethnopharmacology 20100915

Title: Determination of asperosaponin VI in rat plasma by HPLC-ESI-MS and its application to preliminary pharmacokinetic studies.

Journal: Biomedical chromatography : BMC 20100501

Title: Protective roles of Asperosaponin VI, a triterpene saponin isolated from Dipsacus asper Wall on acute myocardial infarction in rats.

Journal: European journal of pharmacology 20100210

Title: Akebia saponin D, a saponin component from Dipsacus asper Wall, protects PC 12 cells against amyloid-beta induced cytotoxicity.

Journal: Cell biology international 20091001

Title: Niu Y, et al. Asperosaponin VI, a saponin component from Dipsacus asper wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway. Phytother Res. 2011 Nov;25(11):1700-6.

Title: Li C, et al. Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways. Eur J Pharmacol. 2010 Dec 15;649(1-3):100-7.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
Submit
SDS
Related Products of 39524-08-8
102040-03-9

102040-03-9

 129741-57-7

129741-57-7

 115810-12-3

115810-12-3

 106577-39-3

106577-39-3

 148409-20-5

148409-20-5

 27013-91-8

27013-91-8
Building Blocks
More >
Historical Records
815-58-7

815-58-7
Tags:39524-08-8 Molecular Formula|39524-08-8 MDL|39524-08-8 SMILES|39524-08-8 Asperosaponin VI
Catalog No.: AA00C7AH
39524-08-8,MFCD25371916
39524-08-8 | Asperosaponin VI
Pack Size： 1mg
Purity： 98% by HPLC
in stock
$77.00 $54.00
Pack Size： 10mg
Purity： ≥98%
in stock
$98.00 $68.00
Pack Size： 50mg
Purity： ≥98%
in stock
$432.00 $302.00
Pack Size： 100mg
Purity： ≥98%
in stock
$765.00 $535.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00C7AH
Chemical Name: Asperosaponin VI
CAS Number: 39524-08-8
Molecular Formula: C47H76O18
Molecular Weight: 929.0955
MDL Number: MFCD25371916
SMILES: OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](OC(=O)[C@]34CC[C@@]5(C(=CC[C@H]6[C@@]5(C)CC[C@@H]5[C@]6(C)CC[C@@H]([C@@]5(C)CO)O[C@@H]5OC[C@@H]([C@@H]([C@H]5O)O)O)[C@@H]4CC(CC3)(C)C)C)[C@@H]([C@H]([C@@H]2O)O)O)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Complexity: 1770  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 23  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 65  
Hydrogen Bond Acceptor Count: 18  
Hydrogen Bond Donor Count: 11  
Isotope Atom Count: 0  
Rotatable Bond Count: 10  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 0.8  
Upstream Synthesis Route
97240-03-4    39524-08-8 

[1]ChemicalandPharmaceuticalBulletin,1985,vol.33,#8,p.3473-3478

14216-03-6    17184-21-3    39524-08-8    99624-66-5    27013-91-8 

[1]ChemicalandPharmaceuticalBulletin,1985,vol.33,#8,p.3473-3478

12672-45-6    39524-08-8 

[1]Phytochemistry,1993,vol.34,#5,p.1389-1394

Downstream Synthesis Route
14216-03-6    17184-21-3    39524-08-8    99624-66-5    27013-91-8 

[1]ChemicalandPharmaceuticalBulletin,1985,vol.33,p.3473-3478

39524-08-8    536-11-8    17184-21-3 

[1]LiebigsAnnalenderChemie,1992,p.453-460

39524-08-8    17184-21-3 

[1]Phytochemistry,1993,vol.34,p.1389-1394

[2]LiebigsAnnalenderChemie,1986,vol.1986,p.638-646

39524-08-8    17184-21-3    39524-13-5 

[1]ChemicalandPharmaceuticalBulletin,1985,vol.33,p.3473-3478

12672-45-6    39524-08-8 

[1]Phytochemistry,1993,vol.34,p.1389-1394

Literature fold

Title: Long-term oral Asperosaponin VI attenuates cardiac dysfunction, myocardial fibrosis in a rat model of chronic myocardial infarction.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20120501

Title: Akebia saponin D attenuates ibotenic acid-induced cognitive deficits and pro-apoptotic response in rats: involvement of MAPK signal pathway.

Journal: Pharmacology, biochemistry, and behavior20120501

Title: Determination of asperosaponin VI in dog plasma by high-performance liquid chromatography-tandem mass spectrometry and its application to a pilot pharmacokinetic study.

Journal: Biomedical chromatography : BMC20120101

Title: Simultaneous determination of asperosaponin VI and its active metabolite hederagenin in rat plasma by liquid chromatography-tandem mass spectrometry with positive/negative ion-switching electrospray ionization and its application in pharmacokinetic study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20111115

Title: [Studies on optimizing preparation technics of wumeitougu oral liquid by response surface methodology].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20110201

Title: Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways.

Journal: European journal of pharmacology20101215

Title: In vitro & in vivo assessment of a herbal formula used topically for bone fracture treatment.

Journal: Journal of ethnopharmacology20100915

Title: Determination of asperosaponin VI in rat plasma by HPLC-ESI-MS and its application to preliminary pharmacokinetic studies.

Journal: Biomedical chromatography : BMC20100501

Title: Protective roles of Asperosaponin VI, a triterpene saponin isolated from Dipsacus asper Wall on acute myocardial infarction in rats.

Journal: European journal of pharmacology20100210

Title: Akebia saponin D, a saponin component from Dipsacus asper Wall, protects PC 12 cells against amyloid-beta induced cytotoxicity.

Journal: Cell biology international20091001

Title: Niu Y, et al. Asperosaponin VI, a saponin component from Dipsacus asper wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway. Phytother Res. 2011 Nov;25(11):1700-6.

Title: Li C, et al. Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways. Eur J Pharmacol. 2010 Dec 15;649(1-3):100-7.

Related Products of of 39524-08-8
102040-03-9
102040-03-9
129741-57-7
129741-57-7
115810-12-3
115810-12-3
106577-39-3
106577-39-3
148409-20-5
148409-20-5
27013-91-8
27013-91-8
Building Blocks More >
35978-39-3
35978-39-3
5-Phenylthieno[2,3-d]pyrimidin-4-one
AA00C7I8 | MFCD00126441
367453-05-2
367453-05-2
H-Hyp(tbu)-otbu hcl
AA00C7NP | MFCD01862362
369611-58-5
369611-58-5
Z-D-Dab(fmoc)-oh
AA00C7XF | MFCD06796914
3235-68-5
3235-68-5
2-(Piperidin-1-yl)acetic acid, HCl
AA00C838 | MFCD01701566
401892-47-5
401892-47-5
5-Bromo-2-chloro-4-iodopyridine
AA00C877 | MFCD09972189
36292-95-2
36292-95-2
2-chloro-N-[1-(2,5-dimethylphenyl)ethyl]acetamide
AA00C8B3 | MFCD07163590
38778-05-1
38778-05-1
4-Phenoxybenzenethiol
AA00C8F3 | MFCD00460414
39155-38-9
39155-38-9
(4-Methylcyclohex-3-en-1-yl)methanol
AA00C8J1 | MFCD01451643
40359-32-8
40359-32-8
3-(Allyloxy)benzaldehyde
AA00C8O2 | MFCD04227161
38956-80-8
38956-80-8
3-Hydrazino-6-phenylpyridazine
AA00C8RS | MFCD01219682
Historical Records
815-58-7
815-58-7
Submit
© 2017 AA BLOCKS, INC. All rights reserved.