Home Amines 3371-85-5
3371-85-5,MFCD30723103
Catalog No.:AA00CIFM

3371-85-5 | methyl 12-methoxy-13-(17-methoxy-17-oxovobasan-3alpha-yl)ibogamine-18-carboxylate

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1mg
≥98%
in stock  
$116.00   $81.00
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5mg
≥98%
in stock  
$313.00   $219.00
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10mg
≥98%
in stock  
$566.00   $396.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00CIFM
Chemical Name:
methyl 12-methoxy-13-(17-methoxy-17-oxovobasan-3alpha-yl)ibogamine-18-carboxylate
CAS Number:
3371-85-5
Molecular Formula:
C43H52N4O5
Molecular Weight:
704.8968
MDL Number:
MFCD30723103
SMILES:
COC(=O)[C@H]1[C@H]2C[C@H](c3cc4[nH]c5c(c4cc3OC)CCN3[C@@H]4[C@]5(C[C@@H](C[C@@H]4CC)C3)C(=O)OC)c3c(C[C@@H]1N(C/C/2=C\C)C)c1ccccc1[nH]3
Properties
Computed Properties
 
Complexity:
1410  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
7  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
52  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
1  
XLogP3:
6.1  

Literature

Title: The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells.

Journal: Autophagy 20081101

Title: Autophagy-mediated chemosensitizing effect of the plant alkaloid voacamine on multidrug resistant cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20070301

Title: Voacamine, an alkaloid extracted from Peschiera fuchsiaefolia, inhibits P-glycoprotein action in multidrug-resistant tumor cells.

Journal: International journal of oncology 20051201

Title: Voacamine, a bisindolic alkaloid from Peschiera fuchsiaefolia, enhances the cytotoxic effect of doxorubicin on multidrug-resistant tumor cells.

Journal: International journal of oncology 20031201

Title: Doubts cast on antimalarial drug.

Journal: The Lancet. Infectious diseases 20030201

Title: Treatment of allergic rhinitis: H1-antihistamines and intranasal steroids.

Journal: Current drug targets. Inflammation and allergy 20020901

Title: Liquid chromatographic/mass spectrometric determination of biologically active alkaloids in extracts of Peschiera fuschiaefolia.

Journal: Journal of mass spectrometry : JMS 20020201

Title: Biological activities of the plant-derived bisindole voacamine with reference to malaria.

Journal: Phytotherapy research : PTR 20010201

Title: Kitajima M, et al. Discovery of indole alkaloids with cannabinoid CB1 receptor antagonistic activity. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1962-4.

Title: Meschini S, et al. Voacamine, an alkaloid extracted from Peschiera fuchsiaefolia, inhibits P-glycoprotein action in multidrug-resistant tumor cells. Int J Oncol. 2005 Dec;27(6):1597-603.

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Tags:3371-85-5 Molecular Formula|3371-85-5 MDL|3371-85-5 SMILES|3371-85-5 methyl 12-methoxy-13-(17-methoxy-17-oxovobasan-3alpha-yl)ibogamine-18-carboxylate