Home Amines 53296-10-9
53296-10-9,MFCD00055119
Catalog No.:AA00D9NW

53296-10-9 | (2R,3R,4S,5R)-2-(6-Amino-2-(phenylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

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5mg
≥98%
in stock  
$65.00   $45.00
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10mg
≥98%
in stock  
$103.00   $72.00
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25mg
≥98%
in stock  
$238.00   $166.00
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50mg
≥98%
in stock  
$440.00   $308.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00D9NW
Chemical Name:
(2R,3R,4S,5R)-2-(6-Amino-2-(phenylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
CAS Number:
53296-10-9
Molecular Formula:
C16H18N6O4
Molecular Weight:
358.3519
MDL Number:
MFCD00055119
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Nc1ccccc1)nc2N
Properties
Computed Properties
 
Complexity:
482  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
4  
XLogP3:
0.8  

Literature

Title: Adenosine A2A receptor as a drug discovery target.

Journal: Journal of medicinal chemistry 20140508

Title: Afferent arteriolar vasodilator effect of adenosine predominantly involves adenosine A2B receptor activation.

Journal: American journal of physiology. Renal physiology 20100801

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Determination of adenosine effects and adenosine receptors in murine corpus cavernosum.

Journal: The Journal of pharmacology and experimental therapeutics 20070801

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors.

Journal: Biochemical pharmacology 19990101

Title: Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261.

Journal: British journal of pharmacology 19970501

Title: Further confirmation of the role of adenyl cyclase and of cAMP-dependent protein kinase in primary afferent hyperalgesia.

Journal: Neuroscience 19910101

Title: Hemodynamic effects of adenosine agonists in the conscious spontaneously hypertensive rat.

Journal: The Journal of pharmacology and experimental therapeutics 19900901

Title: Comparison of the behavioral effects of adenosine agonists and dopamine antagonists in mice.

Journal: Psychopharmacology 19890101

Title: Effect of 2-phenylaminoadenosine (CV-1808) on ischemic ST-segment elevation in anesthetized dogs.

Journal: Journal of cardiovascular pharmacology 19810101

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SDS
Tags:53296-10-9 Molecular Formula|53296-10-9 MDL|53296-10-9 SMILES|53296-10-9 (2R,3R,4S,5R)-2-(6-Amino-2-(phenylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol