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5168-36-5,MFCD00025567
Catalog No.:AA00D9WQ

5168-36-5 | 5-HYDROXY-2'-DEOXYURIDINE

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$102.00   $72.00
- +
2mg
95%
1 week  
$120.00   $84.00
- +
5mg
95%
1 week  
$162.00   $113.00
- +
10mg
95%
1 week  
$210.00   $147.00
- +
25mg
95%
1 week  
$312.00   $219.00
- +
50mg
95%
1 week  
$438.00   $307.00
- +
100mg
95%
1 week  
$627.00   $439.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00D9WQ
Chemical Name:
5-HYDROXY-2'-DEOXYURIDINE
CAS Number:
5168-36-5
Molecular Formula:
C9H12N2O6
Molecular Weight:
244.2014
MDL Number:
MFCD00025567
SMILES:
OC[C@H]1O[C@H](C[C@@H]1O)n1cc(O)c(=O)[nH]c1=O
Properties
Computed Properties
 
Complexity:
382  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
2  
XLogP3:
-1.7  

Literature

Title: 5-Modified-2'-dU and 2'-dC as mutagenic anti HIV-1 proliferation agents: synthesis and activity.

Journal: Journal of medicinal chemistry 20100225

Title: 3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods.

Journal: Bioorganic & medicinal chemistry letters 20060215

Title: Synthesis and in vitro anti-mycobacterial activity of 5-substituted pyrimidine nucleosides.

Journal: Bioorganic & medicinal chemistry 20051215

Title: Oxidation of 5-hydroxypyrimidine nucleosides to 5-hydroxyhydantoin and its alpha-hydroxy-ketone isomer.

Journal: Chemical research in toxicology 20050801

Title: Oxidation of 5-hydroxy-2'-deoxyuridine into isodialuric acid, dialuric acid, and hydantoin products.

Journal: Journal of the American Chemical Society 20040602

Title: Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans.

Journal: Chembiochem : a European journal of chemical biology 20030804

Title: Design of Mycobacterium tuberculosis thymidine monophosphate kinase inhibitors.

Journal: Nucleosides, nucleotides & nucleic acids 20030101

Title: New substrates for old enzymes. 5-Hydroxy-2'-deoxycytidine and 5-hydroxy-2'-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2'-deoxyuridine is a substrate for uracil DNA N-glycosylase.

Journal: The Journal of biological chemistry 19940722

Title: Comparison of susceptibilities of varicella-zoster virus and herpes simplex viruses to nucleoside analogs.

Journal: Antimicrobial agents and chemotherapy 19860301

Title: 5-O-Alkylated derivatives of 5-hydroxy-2'-deoxyuridine as potential antiviral agents. Anti-herpes activity of 5-propynyloxy-2'-deoxyuridine.

Journal: Journal of medicinal chemistry 19780201

Title: Nucleosides. 3. Studies on 5-methylamino-2'-deoxyuridine as a specific antiherpes agent.

Journal: Journal of medicinal chemistry 19660501

Title: Purmal AA, et al. Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro. Nucleic Acids Res. 1994 Jan 11;22(1):72-8.

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SDS
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